Overview

ID MAG01731
Name HKD1_bin.49
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Rhizobiales
Family Hyphomicrobiaceae
Genus Hyphomicrobium_A
Species Hyphomicrobium_A sp035517115
Assembly information
Completeness (%) 86.63
Contamination (%) 0.36
GC content (%) 66.0
N50 (bp) 10,971
Genome size (bp) 2,433,101

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2299

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1002531_0 Extracellular solute-binding protein K02035,K13893 - - 6.78e-259 810.0
HKD1_k127_1002531_1 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 392.0
HKD1_k127_1002531_2 Invasion associated locus B (IalB) protein - - - 0.0000000000000000000000000000000000000006356 165.0
HKD1_k127_1020122_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 549.0
HKD1_k127_1020122_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 402.0
HKD1_k127_1020122_10 Belongs to the Fur family K09823 - - 0.00000000000000000000000000000000000000000000000000001516 195.0
HKD1_k127_1020122_11 Membrane fusogenic activity K09806 - - 0.00000000000000000000000008397 112.0
HKD1_k127_1020122_2 Putative S-adenosyl-L-methionine-dependent methyltransferase K00574,K18164 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 385.0
HKD1_k127_1020122_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 329.0
HKD1_k127_1020122_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 317.0
HKD1_k127_1020122_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 309.0
HKD1_k127_1020122_6 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 304.0
HKD1_k127_1020122_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 301.0
HKD1_k127_1020122_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001513 250.0
HKD1_k127_1020122_9 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000002196 209.0
HKD1_k127_1041687_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00123 - 1.17.1.9 0.0 1131.0
HKD1_k127_1041687_1 GMC oxidoreductase K03333 - 1.1.3.6 6.362e-248 791.0
HKD1_k127_1041687_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 320.0
HKD1_k127_1041687_3 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000000002788 164.0
HKD1_k127_1041687_4 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.0000000000000000000007656 96.0
HKD1_k127_1048980_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1729.0
HKD1_k127_1048980_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 363.0
HKD1_k127_1048980_2 Glutathione S-transferase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 315.0
HKD1_k127_1048980_3 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000694 228.0
HKD1_k127_1048980_4 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000004633 196.0
HKD1_k127_1048980_5 AAA domain - - - 0.0000000000000000000000000000006098 124.0
HKD1_k127_1049639_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002748 286.0
HKD1_k127_1049639_1 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001006 295.0
HKD1_k127_1049639_2 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001101 216.0
HKD1_k127_1049639_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000005838 143.0
HKD1_k127_1049639_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000002151 86.0
HKD1_k127_1050250_0 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 489.0
HKD1_k127_1050250_1 amidase activity K01448,K02395,K17733 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 404.0
HKD1_k127_1050250_2 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 364.0
HKD1_k127_1050250_3 N-Acetylmuramoyl-L-alanine amidase K01448 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 305.0
HKD1_k127_1050250_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000614 245.0
HKD1_k127_1057196_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 7.94e-285 881.0
HKD1_k127_1057196_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 3.74e-222 699.0
HKD1_k127_1057196_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 508.0
HKD1_k127_1057196_3 amino acid peptide transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 366.0
HKD1_k127_1057196_4 Protein of unknown function (DUF2865) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 364.0
HKD1_k127_1057196_5 PFAM GCN5-related N-acetyltransferase - - - 0.000000000006684 73.0
HKD1_k127_1066410_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 7.179e-239 749.0
HKD1_k127_1066410_1 Major facilitator superfamily K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 598.0
HKD1_k127_1066410_2 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 580.0
HKD1_k127_1066410_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 460.0
HKD1_k127_1066410_5 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 289.0
HKD1_k127_1066410_6 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001152 244.0
HKD1_k127_1066410_7 Pfam:TPM K08988 - - 0.000000000000000000000000000000000000000000000000000000000000001251 224.0
HKD1_k127_1091617_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.0 1076.0
HKD1_k127_1091617_1 Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.0 1054.0
HKD1_k127_1091617_10 Phosphorylase superfamily - - - 0.00000000000000000000000000000000000002922 154.0
HKD1_k127_1091617_2 Hopanoid biosynthesis associated radical SAM protein HpnH - - - 8.453e-223 694.0
HKD1_k127_1091617_3 amine oxidase K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 540.0
HKD1_k127_1091617_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 466.0
HKD1_k127_1091617_5 Hopene-associated glycosyltransferase HpnB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 460.0
HKD1_k127_1091617_6 squalene synthase HpnC K21678,K21679 - 2.5.1.103,4.2.3.156 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 345.0
HKD1_k127_1091617_7 phytoene synthase K21678 - 2.5.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 311.0
HKD1_k127_1091617_8 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004416 273.0
HKD1_k127_1091617_9 YXWGXW repeat (2 copies) - - - 0.000000000000000000000000000000000000000009268 159.0
HKD1_k127_109326_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.2e-228 716.0
HKD1_k127_109326_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 412.0
HKD1_k127_109326_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000697 347.0
HKD1_k127_109326_3 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005852 278.0
HKD1_k127_109326_4 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000002166 178.0
HKD1_k127_109326_5 cell cycle - - - 0.0000000000000000000000000000001717 126.0
HKD1_k127_1096946_0 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 534.0
HKD1_k127_1096946_1 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 439.0
HKD1_k127_1096946_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 405.0
HKD1_k127_1096946_3 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 362.0
HKD1_k127_1096946_4 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 341.0
HKD1_k127_1096946_5 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 336.0
HKD1_k127_1096946_6 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000181 260.0
HKD1_k127_1096946_7 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000001699 154.0
HKD1_k127_1096946_8 Response regulator receiver - - - 0.000000000000000000001716 100.0
HKD1_k127_1096946_9 - - - - 0.00000000000000000002752 92.0
HKD1_k127_1103168_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 2.209e-231 726.0
HKD1_k127_1103168_1 FtsX-like permease family K02004 - - 1.389e-209 662.0
HKD1_k127_1103168_10 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 463.0
HKD1_k127_1103168_11 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 325.0
HKD1_k127_1103168_12 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 305.0
HKD1_k127_1103168_13 Protein of unknown function (DUF3299) K09950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002288 259.0
HKD1_k127_1103168_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001106 241.0
HKD1_k127_1103168_15 Thioredoxin-like - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000004141 234.0
HKD1_k127_1103168_16 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000000000000000000000000005897 215.0
HKD1_k127_1103168_17 Protein of unknown function (DUF2796) - - - 0.000000000000000000000000000000000000000000000005858 188.0
HKD1_k127_1103168_18 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000009226 157.0
HKD1_k127_1103168_19 Cytochrome c K08738 - - 0.000000000000000000000000000000004897 146.0
HKD1_k127_1103168_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 4.738e-207 650.0
HKD1_k127_1103168_21 - - - - 0.00000000000000000004174 92.0
HKD1_k127_1103168_23 small periplasmic lipoprotein - - - 0.000000000001237 73.0
HKD1_k127_1103168_24 - - - - 0.00000003237 57.0
HKD1_k127_1103168_3 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 4.472e-206 648.0
HKD1_k127_1103168_4 acetylornithine K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 582.0
HKD1_k127_1103168_5 Domain of unknown function (DUF4175) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 591.0
HKD1_k127_1103168_6 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 539.0
HKD1_k127_1103168_7 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 526.0
HKD1_k127_1103168_8 2-deoxycytidine 5-triphosphate deaminase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009858 518.0
HKD1_k127_1103168_9 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 507.0
HKD1_k127_1111891_0 MltA specific insert domain K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 417.0
HKD1_k127_1111891_1 import inner membrane translocase subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002694 275.0
HKD1_k127_1111891_2 PFAM FxsA cytoplasmic membrane protein K07113 - - 0.000000000000000000007544 97.0
HKD1_k127_1111891_3 Smr domain - - - 0.000000000000007223 80.0
HKD1_k127_1137863_0 Biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 3.348e-270 833.0
HKD1_k127_1137863_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 347.0
HKD1_k127_1137863_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000002938 222.0
HKD1_k127_1137863_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000009061 212.0
HKD1_k127_1137863_4 Protein of unknown function (DUF3300) - - - 0.00000000000000000000001312 104.0
HKD1_k127_1137863_5 DSBA-like thioredoxin domain - - - 0.00000000000002985 72.0
HKD1_k127_1168503_0 lipid A ABC exporter family, fused ATPase and inner membrane subunits K06147 - - 3.007e-239 754.0
HKD1_k127_1168503_1 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 532.0
HKD1_k127_1168503_10 ribosomal protein L31 K02909 - - 0.000000000000000000000000000000000000206 144.0
HKD1_k127_1168503_11 Protein of unknown function (DUF1192) - - - 0.0000000000000007312 79.0
HKD1_k127_1168503_12 - - - - 0.0000000000000009461 80.0
HKD1_k127_1168503_13 - - - - 0.00001663 51.0
HKD1_k127_1168503_2 MotA TolQ ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 515.0
HKD1_k127_1168503_3 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 477.0
HKD1_k127_1168503_4 inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 397.0
HKD1_k127_1168503_5 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 366.0
HKD1_k127_1168503_6 Protein of unknown function (DUF1465) K13592 - - 0.000000000000000000000000000000000000000000000000000000213 201.0
HKD1_k127_1168503_7 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000000000000000005387 178.0
HKD1_k127_1168503_8 Haem-degrading - - - 0.00000000000000000000000000000000000000000002775 161.0
HKD1_k127_1168503_9 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000008659 168.0
HKD1_k127_1172830_0 glutamine synthetase K01915 - 6.3.1.2 2.075e-269 833.0
HKD1_k127_1172830_1 Tetratricopeptide repeat - - - 8.419e-194 621.0
HKD1_k127_1172830_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 581.0
HKD1_k127_1172830_3 Protein of unknown function (DUF1134) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 362.0
HKD1_k127_1172830_4 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 355.0
HKD1_k127_1172830_5 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000000000000000971 207.0
HKD1_k127_1172830_6 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000006234 167.0
HKD1_k127_1172830_7 Thioesterase superfamily - - - 0.00000000000000000000000000000007343 130.0
HKD1_k127_1262371_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 8.623e-212 674.0
HKD1_k127_1262371_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 567.0
HKD1_k127_1262371_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 392.0
HKD1_k127_1262371_3 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 385.0
HKD1_k127_1262371_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001757 278.0
HKD1_k127_1262371_6 CHAD - - - 0.00000000000000000000000000000000000000000000000000000002266 209.0
HKD1_k127_1262371_7 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000001364 57.0
HKD1_k127_1313630_0 Glycosyl transferase family group 2 K03669 GO:0005575,GO:0016020 - 1.266e-245 781.0
HKD1_k127_1313630_1 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0051273,GO:0051274,GO:0071704,GO:1901576 - 2.399e-202 645.0
HKD1_k127_1313630_2 YcjX-like family, DUF463 K06918 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 557.0
HKD1_k127_1313630_3 Domain of unknown function (DUF697) K08990 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 349.0
HKD1_k127_1313630_4 Gram-negative porin - - - 0.000003214 49.0
HKD1_k127_1347816_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1005.0
HKD1_k127_1347816_1 BolA-like protein - - - 0.000000000000000000000000000000002825 129.0
HKD1_k127_1367112_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1334.0
HKD1_k127_1367112_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 396.0
HKD1_k127_1367112_2 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 313.0
HKD1_k127_1367112_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000009459 244.0
HKD1_k127_1367112_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000003221 226.0
HKD1_k127_1367112_5 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000000000003141 178.0
HKD1_k127_1367112_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000001696 172.0
HKD1_k127_1367112_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000385 102.0
HKD1_k127_139807_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1015.0
HKD1_k127_139807_1 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 451.0
HKD1_k127_139807_2 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 336.0
HKD1_k127_139807_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 299.0
HKD1_k127_139807_4 Putative diguanylate phosphodiesterase K13593 - - 0.00000000000000000000000000000000000000000000000000000000000000002515 235.0
HKD1_k127_139807_5 PFAM Extensin family protein - - - 0.0000000000000000000000000000000000000000000000000000000003946 216.0
HKD1_k127_139807_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000003142 79.0
HKD1_k127_140256_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 534.0
HKD1_k127_140256_2 recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 413.0
HKD1_k127_140256_3 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 399.0
HKD1_k127_140256_4 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 353.0
HKD1_k127_140256_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001014 258.0
HKD1_k127_140256_6 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000001874 217.0
HKD1_k127_1413993_0 Glycosyl transferase family group 2 K22278 - 3.5.1.104 0.0 1358.0
HKD1_k127_1448925_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1304.0
HKD1_k127_1448925_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 2.898e-214 697.0
HKD1_k127_1448925_10 DSBA-like thioredoxin domain - - - 0.000000000001839 74.0
HKD1_k127_1448925_2 Peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 611.0
HKD1_k127_1448925_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 544.0
HKD1_k127_1448925_4 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 463.0
HKD1_k127_1448925_5 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 429.0
HKD1_k127_1448925_6 MafB19-like deaminase - - - 0.000000000000000000000000000000000000000001017 158.0
HKD1_k127_1448925_7 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000006029 115.0
HKD1_k127_1448925_8 Thioredoxin - - - 0.00000000000000000000000008366 111.0
HKD1_k127_1448925_9 LTXXQ motif family protein - - - 0.0000000000000000000000002033 114.0
HKD1_k127_146666_0 Belongs to the HpcH HpaI aldolase family K01644,K08691 GO:0003674,GO:0003824,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872,GO:0047777,GO:0050083 4.1.3.24,4.1.3.25,4.1.3.34 5.735e-208 652.0
HKD1_k127_146666_1 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 455.0
HKD1_k127_146666_10 Hemimethylated DNA-binding protein YccV like K11940 - - 0.000000000000000000000000000000001735 130.0
HKD1_k127_146666_11 epimerase - - - 0.0000000000000000000001468 102.0
HKD1_k127_146666_12 - - - - 0.000000000000000000001535 102.0
HKD1_k127_146666_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 462.0
HKD1_k127_146666_3 FAD binding domain K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008656 429.0
HKD1_k127_146666_4 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 317.0
HKD1_k127_146666_5 AraC-binding-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000001745 230.0
HKD1_k127_146666_6 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.00000000000000000000000000000000000000000000000000000000000907 215.0
HKD1_k127_146666_7 - - - - 0.0000000000000000000000000000000000004515 145.0
HKD1_k127_146666_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000001408 139.0
HKD1_k127_146666_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000007661 150.0
HKD1_k127_148763_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 1.877e-219 697.0
HKD1_k127_148763_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 548.0
HKD1_k127_148763_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 473.0
HKD1_k127_148763_3 peptidyl-prolyl isomerase K01802,K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 293.0
HKD1_k127_148763_4 transcriptional K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000403 126.0
HKD1_k127_1506550_0 ABC transporter transmembrane region K02021,K06147,K11085 - - 4.051e-240 758.0
HKD1_k127_1506550_1 Domain of unknown function (DUF374) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 1.237e-230 733.0
HKD1_k127_1506550_10 Uncharacterized protein conserved in bacteria (DUF2093) - - - 0.0000000000000000000000000000004831 124.0
HKD1_k127_1506550_11 Domain of unknown function (DUF4170) - - - 0.00000000000000000000000000003661 120.0
HKD1_k127_1506550_2 Belongs to the GARS family K01945 - 6.3.4.13 4.813e-205 646.0
HKD1_k127_1506550_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 9.89e-205 648.0
HKD1_k127_1506550_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 357.0
HKD1_k127_1506550_5 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 344.0
HKD1_k127_1506550_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 336.0
HKD1_k127_1506550_7 Protein tyrosine serine phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 298.0
HKD1_k127_1506550_8 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000001706 222.0
HKD1_k127_1506550_9 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan K01233 GO:0003674,GO:0003824,GO:0004553,GO:0016787,GO:0016798,GO:0016977 3.2.1.132 0.00000000000000000000000000000000000000000005099 171.0
HKD1_k127_1520187_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 466.0
HKD1_k127_1520187_1 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 330.0
HKD1_k127_1520187_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000001551 91.0
HKD1_k127_1578351_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1171.0
HKD1_k127_1578351_1 amine oxidase - - - 1.014e-259 809.0
HKD1_k127_1578351_10 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000001492 162.0
HKD1_k127_1578351_11 Protein of unknown function (DUF1761) - - - 0.00000000000000000000000000000000000001693 148.0
HKD1_k127_1578351_12 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000042 135.0
HKD1_k127_1578351_13 GtrA-like protein - - - 0.000000000000000000008461 99.0
HKD1_k127_1578351_2 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 617.0
HKD1_k127_1578351_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 477.0
HKD1_k127_1578351_4 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 456.0
HKD1_k127_1578351_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 368.0
HKD1_k127_1578351_6 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 372.0
HKD1_k127_1578351_7 Ribosomal protein L11 methyltransferase (PrmA) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 304.0
HKD1_k127_1578351_8 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001844 261.0
HKD1_k127_1578351_9 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000001482 219.0
HKD1_k127_1603317_0 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 446.0
HKD1_k127_1603317_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 312.0
HKD1_k127_1603317_2 amino acid peptide transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 297.0
HKD1_k127_1603317_3 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 293.0
HKD1_k127_1603317_4 Bacterial signalling protein N terminal repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000001623 239.0
HKD1_k127_161260_0 chorismate binding enzyme K01665,K03342 - 2.6.1.85,4.1.3.38 9.466e-282 889.0
HKD1_k127_161260_1 - - - - 8.241e-198 633.0
HKD1_k127_161260_11 - - - - 0.0000000000001834 76.0
HKD1_k127_161260_12 Alpha beta hydrolase K03928 - 3.1.1.1 0.0000000003387 64.0
HKD1_k127_161260_13 - - - - 0.00000000088 67.0
HKD1_k127_161260_14 - - - - 0.0000005596 56.0
HKD1_k127_161260_15 Bacteriophage replication gene A protein (GPA) - - - 0.0000006857 53.0
HKD1_k127_161260_16 Domain of unknown function (DUF892) - - - 0.00001274 55.0
HKD1_k127_161260_2 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 578.0
HKD1_k127_161260_3 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 502.0
HKD1_k127_161260_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 340.0
HKD1_k127_161260_5 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 346.0
HKD1_k127_161260_6 Ion channel K10716 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 311.0
HKD1_k127_161260_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000006232 245.0
HKD1_k127_161260_8 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000002588 196.0
HKD1_k127_161260_9 Lipid A Biosynthesis N-terminal domain - - - 0.000000000000000000000000000000000000002716 149.0
HKD1_k127_1618706_0 Binding-protein-dependent transport system inner membrane component K02050 - - 2.378e-225 711.0
HKD1_k127_1618706_1 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 530.0
HKD1_k127_1618706_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 488.0
HKD1_k127_1618706_3 Protein conserved in bacteria K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 471.0
HKD1_k127_1618706_4 GntP family permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 413.0
HKD1_k127_1618706_5 GntP family permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005626 280.0
HKD1_k127_1618706_6 TPR repeat - - - 0.0000000000000000000000000009504 130.0
HKD1_k127_1618706_7 Short repeat of unknown function (DUF308) - - - 0.0000000000000001268 79.0
HKD1_k127_1618706_8 BFD-like [2Fe-2S] binding domain - - - 0.0000000000216 67.0
HKD1_k127_1618706_9 Cytochrome P460 - - - 0.0000000001734 68.0
HKD1_k127_1626330_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1124.0
HKD1_k127_1626330_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 559.0
HKD1_k127_1626330_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 550.0
HKD1_k127_1626330_3 SmpA / OmlA family - - - 0.00000000000000000000000000000000000000000000000000000001129 203.0
HKD1_k127_1626330_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000000000001427 181.0
HKD1_k127_1626330_5 Uncharacterized ACR, COG1399 - - - 0.0000000000000000000000000000000000000000002273 166.0
HKD1_k127_1626330_6 MerR family regulatory protein - - - 0.000000000000000000000000000000000000000001518 159.0
HKD1_k127_1626330_7 Ubiquinol-cytochrome C chaperone K17662 - - 0.00000000000000000000000000000000005322 141.0
HKD1_k127_171173_0 Belongs to the peptidase M16 family K07263 - - 5.098e-208 655.0
HKD1_k127_171173_1 Peptidase M16 inactive domain K07263,K07623 - - 1.34e-196 622.0
HKD1_k127_171173_10 Thioredoxin-like - - - 0.0000000000000000000000000000000003015 138.0
HKD1_k127_171173_11 Protein of unknown function (DUF1150) - - - 0.000000000000000000000000000002643 121.0
HKD1_k127_171173_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 433.0
HKD1_k127_171173_3 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 348.0
HKD1_k127_171173_4 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 338.0
HKD1_k127_171173_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 309.0
HKD1_k127_171173_6 PFAM cytochrome c biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000775 310.0
HKD1_k127_171173_7 methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000003999 246.0
HKD1_k127_171173_8 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.0000000000000000000000000000000000000000000000000000000000000000246 226.0
HKD1_k127_171173_9 Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000000000000000000000000000000000000000000414 207.0
HKD1_k127_181000_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 514.0
HKD1_k127_181000_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 507.0
HKD1_k127_181000_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000002822 230.0
HKD1_k127_181000_3 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000002618 170.0
HKD1_k127_1888963_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 2.056e-229 715.0
HKD1_k127_1888963_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000001477 188.0
HKD1_k127_1888963_4 - - - - 0.00000000000000000008562 90.0
HKD1_k127_192488_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.0 1100.0
HKD1_k127_192488_1 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 368.0
HKD1_k127_192488_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001834 241.0
HKD1_k127_192488_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799,K18990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009879 242.0
HKD1_k127_192488_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.000000000000000000000000000000000000000000000000000000000000000000327 232.0
HKD1_k127_192488_5 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000000000000000000002272 186.0
HKD1_k127_2018426_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.109e-263 827.0
HKD1_k127_2018426_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 499.0
HKD1_k127_2032398_0 exonuclease RecJ K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 1.426e-248 789.0
HKD1_k127_2032398_1 Phosphoesterase family - - - 1.749e-247 779.0
HKD1_k127_2032398_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 471.0
HKD1_k127_2032398_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 403.0
HKD1_k127_2032398_4 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 375.0
HKD1_k127_2047112_0 Inner membrane protein involved in colicin E2 resistance K06143 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 462.0
HKD1_k127_2047112_1 Linear amide C-N hydrolases, choloylglycine hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 404.0
HKD1_k127_2047112_2 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 385.0
HKD1_k127_2047112_3 Domain of unknown function (DUF4166) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003788 245.0
HKD1_k127_2047112_4 Belongs to the GbsR family - - - 0.000000000000000000000000000000000000000000000000000000000000002122 224.0
HKD1_k127_2047112_5 Phage integrase family - - - 0.00000000000000000000000000000000000000000000001648 177.0
HKD1_k127_2047112_6 Recombinase zinc beta ribbon domain - - - 0.00000000009301 63.0
HKD1_k127_2055354_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 469.0
HKD1_k127_2055354_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 422.0
HKD1_k127_2055354_2 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 389.0
HKD1_k127_2055354_3 Chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 351.0
HKD1_k127_2055354_4 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000007956 222.0
HKD1_k127_2055354_5 protein tyrosine kinase activity - - - 0.00000001128 66.0
HKD1_k127_2062183_0 Transglycosylase SLT domain K08309 - - 5.07e-254 806.0
HKD1_k127_2062183_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008840,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0071704 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 459.0
HKD1_k127_2062183_10 Redoxin domain protein - - - 0.000000000000000000000000000000000000000000000002487 186.0
HKD1_k127_2062183_11 DUF218 domain - - - 0.0000000000000000000000000000000000002035 143.0
HKD1_k127_2062183_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 381.0
HKD1_k127_2062183_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 342.0
HKD1_k127_2062183_4 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 317.0
HKD1_k127_2062183_5 Redoxin domain protein K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 252.0
HKD1_k127_2062183_6 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006603 248.0
HKD1_k127_2062183_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000002285 233.0
HKD1_k127_2062183_8 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000002511 214.0
HKD1_k127_2062183_9 Protein of unknown function (DUF3775) - - - 0.000000000000000000000000000000000000000000000000000000000005926 216.0
HKD1_k127_2064387_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 424.0
HKD1_k127_2064387_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 307.0
HKD1_k127_2064387_2 Single cache domain 3 - - - 0.00000000000000000000000000000000000000000000000000001347 193.0
HKD1_k127_2064387_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000006665 142.0
HKD1_k127_2064387_4 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000003639 136.0
HKD1_k127_2064387_5 Protein of unknown function (DUF1674) - - - 0.000000000000006343 76.0
HKD1_k127_2145015_0 cytochrome P450 - - - 1.589e-263 817.0
HKD1_k127_2145015_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 517.0
HKD1_k127_2145015_2 ABC transporter K06158 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 402.0
HKD1_k127_2145015_3 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 402.0
HKD1_k127_2145015_5 Formyl transferase K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000006163 266.0
HKD1_k127_2145015_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000001507 208.0
HKD1_k127_2145015_7 Peptidogalycan biosysnthesis/recognition - - - 0.000000000000000000000000000000000000000000000001416 186.0
HKD1_k127_2145015_8 COG0262 Dihydrofolate reductase - - - 0.000000000000000000000000000000000009511 143.0
HKD1_k127_2145015_9 - - - - 0.000000000000000000000000000002899 129.0
HKD1_k127_2151793_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 411.0
HKD1_k127_2151793_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002208 257.0
HKD1_k127_2151793_2 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000006938 226.0
HKD1_k127_2151793_3 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000006648 127.0
HKD1_k127_2151793_5 transglycosylase - - - 0.00000000000001713 85.0
HKD1_k127_2152162_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000007305 226.0
HKD1_k127_2152162_1 amine oxidase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000004854 199.0
HKD1_k127_2152162_3 Dienelactone hydrolase family - - - 0.0000000000000004516 89.0
HKD1_k127_2152162_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000002183 61.0
HKD1_k127_2156658_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.067e-302 942.0
HKD1_k127_2156658_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 7.383e-236 740.0
HKD1_k127_2156658_10 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 422.0
HKD1_k127_2156658_11 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 409.0
HKD1_k127_2156658_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 371.0
HKD1_k127_2156658_13 Cell division protein FtsQ K03589 - - 0.0000000000000000000000000000000000000000000000000205 194.0
HKD1_k127_2156658_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 595.0
HKD1_k127_2156658_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 604.0
HKD1_k127_2156658_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 553.0
HKD1_k127_2156658_5 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 527.0
HKD1_k127_2156658_6 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 516.0
HKD1_k127_2156658_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 494.0
HKD1_k127_2156658_8 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 488.0
HKD1_k127_2156658_9 Belongs to the D-alanine--D-alanine ligase family K00075,K01921 - 1.3.1.98,6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 491.0
HKD1_k127_215750_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1523.0
HKD1_k127_215750_1 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 0.0 1017.0
HKD1_k127_215750_2 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 583.0
HKD1_k127_215750_3 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 357.0
HKD1_k127_215750_4 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000005765 244.0
HKD1_k127_215750_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000003114 244.0
HKD1_k127_215750_6 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000001719 217.0
HKD1_k127_215750_7 PFAM Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000000004168 153.0
HKD1_k127_215750_8 - - - - 0.000000000000000000004549 101.0
HKD1_k127_215750_9 - K08086,K09991 - - 0.00001888 56.0
HKD1_k127_2161052_0 Domain of unknown function (DUF4159) - - - 0.0 1210.0
HKD1_k127_2161052_1 membrane - - - 0.0 1052.0
HKD1_k127_2161052_10 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002824 275.0
HKD1_k127_2161052_11 protein conserved in bacteria K09986 - - 0.0000000000000000000000000000000000000000000000000000000000009165 215.0
HKD1_k127_2161052_12 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000001123 189.0
HKD1_k127_2161052_13 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000000000000000002467 185.0
HKD1_k127_2161052_14 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0000000000000000000000000000000000000000003078 164.0
HKD1_k127_2161052_15 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000000005615 157.0
HKD1_k127_2161052_16 PFAM Usg family protein - - - 0.000000000000000000000000000000000000967 149.0
HKD1_k127_2161052_17 - - - - 0.0000000000000000000000000007499 118.0
HKD1_k127_2161052_18 FAD dependent oxidoreductase - - - 0.0000000000000000000002206 97.0
HKD1_k127_2161052_2 ATPase AAA K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 564.0
HKD1_k127_2161052_3 metalloendopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 570.0
HKD1_k127_2161052_4 Binding-protein-dependent transport system inner membrane component K09971 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 518.0
HKD1_k127_2161052_5 Belongs to the bacterial solute-binding protein 3 family K09969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 482.0
HKD1_k127_2161052_6 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009172 458.0
HKD1_k127_2161052_7 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 437.0
HKD1_k127_2161052_8 Binding-protein-dependent transport system inner membrane component K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 432.0
HKD1_k127_2161052_9 ABC transporter K02028,K09972 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 372.0
HKD1_k127_2176788_0 glutamate--cysteine ligase K01919 - 6.3.2.2 7.751e-231 721.0
HKD1_k127_2176788_1 Domain of unknown function (DUF3390) K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 586.0
HKD1_k127_2176788_2 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 350.0
HKD1_k127_2176788_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 323.0
HKD1_k127_2176788_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000001026 188.0
HKD1_k127_2176788_5 LUD domain K00782 - - 0.0000000000000000000000000000000000000000014 169.0
HKD1_k127_2176788_6 Cytochrome c2 K08738 - - 0.000000000000000000000000000000001029 135.0
HKD1_k127_2176788_7 transcriptional regulator - - - 0.0000000000000000001457 90.0
HKD1_k127_2187157_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 9.278e-261 807.0
HKD1_k127_2187157_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 466.0
HKD1_k127_2187157_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 465.0
HKD1_k127_2187157_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 396.0
HKD1_k127_2187157_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 331.0
HKD1_k127_2187157_5 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000000000000000000001938 216.0
HKD1_k127_2187157_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000005323 213.0
HKD1_k127_2187157_7 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000006151 196.0
HKD1_k127_2187157_8 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000001419 188.0
HKD1_k127_2187157_9 protein conserved in bacteria - - - 0.0002061 44.0
HKD1_k127_2187407_0 phosphoenolpyruvate carboxylase activity K01595 - 4.1.1.31 0.0 1414.0
HKD1_k127_2187407_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 8.916e-315 972.0
HKD1_k127_2187407_10 Proteasome-type protease K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 376.0
HKD1_k127_2187407_11 Bacterial transglutaminase-like N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 363.0
HKD1_k127_2187407_12 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 330.0
HKD1_k127_2187407_13 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002516 276.0
HKD1_k127_2187407_14 Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000003007 232.0
HKD1_k127_2187407_2 Circularly permuted ATP-grasp type 2 - - - 4.203e-247 768.0
HKD1_k127_2187407_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.404e-226 708.0
HKD1_k127_2187407_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 - 6.2.1.5,6.2.1.9 2.849e-207 655.0
HKD1_k127_2187407_5 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 8.707e-205 644.0
HKD1_k127_2187407_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 - 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 554.0
HKD1_k127_2187407_7 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 530.0
HKD1_k127_2187407_8 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 468.0
HKD1_k127_2187407_9 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 412.0
HKD1_k127_2196523_0 S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase K13622 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 557.0
HKD1_k127_2196523_1 Zinc-binding dehydrogenase K00344 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003960,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016651,GO:0016655,GO:0017091,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:1901363 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 461.0
HKD1_k127_2196523_10 Cold shock protein domain K03704 - - 0.00000000000000000000000000348 119.0
HKD1_k127_2196523_11 Belongs to the 'phage' integrase family - - - 0.0000000000000000000008156 97.0
HKD1_k127_2196523_2 Bacterial signalling protein N terminal repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 321.0
HKD1_k127_2196523_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 299.0
HKD1_k127_2196523_4 Methyltransferase K13623 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001094 284.0
HKD1_k127_2196523_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000009215 213.0
HKD1_k127_2196523_6 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000003916 206.0
HKD1_k127_2196523_7 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000128 192.0
HKD1_k127_2196523_9 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000002684 116.0
HKD1_k127_2209489_0 ABC transporter K15738 - - 5e-324 996.0
HKD1_k127_2209489_1 Patatin phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000306 280.0
HKD1_k127_2209489_3 PFAM PIN domain - - - 0.0000001163 55.0
HKD1_k127_2209489_4 Plasmid stability protein K21495 - - 0.00008969 51.0
HKD1_k127_2214511_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 4.224e-238 743.0
HKD1_k127_2214511_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858,K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 542.0
HKD1_k127_2214511_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000001837 191.0
HKD1_k127_2214511_11 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000007223 70.0
HKD1_k127_2214511_12 cyclic nucleotide binding K01420 - - 0.0000000001368 67.0
HKD1_k127_2214511_13 5-aminolevulinic acid synthase K00643 - 2.3.1.37 0.0000000002481 61.0
HKD1_k127_2214511_14 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00006021 50.0
HKD1_k127_2214511_2 ErfK YbiS YcfS YnhG family protein K21470,K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 521.0
HKD1_k127_2214511_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 393.0
HKD1_k127_2214511_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 349.0
HKD1_k127_2214511_5 Peptidase family M50 K06402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 331.0
HKD1_k127_2214511_6 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 286.0
HKD1_k127_2214511_7 flavin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001869 274.0
HKD1_k127_2214511_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001487 246.0
HKD1_k127_2214511_9 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000004846 203.0
HKD1_k127_2215500_0 Cadherin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000002431 239.0
HKD1_k127_2215500_1 cyclic nucleotide binding K01420 - - 0.0000000000000000000000000000000000000001187 163.0
HKD1_k127_2215500_3 Protein of unknown function (DUF3175) - - - 0.0000000000000000003985 96.0
HKD1_k127_2215500_4 Thioesterase superfamily - - - 0.000000002892 63.0
HKD1_k127_2254489_0 Pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 2.016e-231 733.0
HKD1_k127_2254489_1 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 305.0
HKD1_k127_2254489_11 signal-transduction protein containing cAMP-binding and CBS domains K00384 - 1.8.1.9 0.000000001268 64.0
HKD1_k127_2254489_2 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005541 273.0
HKD1_k127_2254489_3 AraC-binding-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001195 253.0
HKD1_k127_2254489_4 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000002546 231.0
HKD1_k127_2254489_5 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000005994 231.0
HKD1_k127_2254489_6 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000008723 173.0
HKD1_k127_2254489_7 diguanylate cyclase - - - 0.0000000000000000000000000000000000000001739 157.0
HKD1_k127_2254489_8 OmpA-like transmembrane domain K16079 - - 0.000000000000000000000000000000001418 139.0
HKD1_k127_2254489_9 Putative diguanylate phosphodiesterase - - - 0.00000000000000000001199 97.0
HKD1_k127_2261580_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 598.0
HKD1_k127_2261580_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000001086 223.0
HKD1_k127_2261580_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000008514 213.0
HKD1_k127_2261580_3 GYD domain - - - 0.0000000000000000000000000000000000007915 141.0
HKD1_k127_2261580_4 - - - - 0.0000000000000000008226 89.0
HKD1_k127_2261580_5 - - - - 0.000000000000000000948 88.0
HKD1_k127_2261580_6 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000005897 76.0
HKD1_k127_2279133_0 helicase superfamily c-terminal domain K17675 - 3.6.4.13 0.0 1305.0
HKD1_k127_2279133_1 Esterase-like activity of phytase - - - 0.0000000000000000000000000000000000000000000000000000000000000009032 223.0
HKD1_k127_2279133_2 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001169 159.0
HKD1_k127_2279133_3 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000005584 156.0
HKD1_k127_2283951_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 425.0
HKD1_k127_2283951_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000004197 110.0
HKD1_k127_2283951_2 Trypsin K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000001802 84.0
HKD1_k127_2287685_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 593.0
HKD1_k127_2287685_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 477.0
HKD1_k127_2287685_2 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 432.0
HKD1_k127_2287685_3 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 389.0
HKD1_k127_2287685_4 Phosphate transport regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 319.0
HKD1_k127_2304927_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 4.259e-226 704.0
HKD1_k127_2304927_1 Polyphosphate kinase 2 (PPK2) K22468 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0044237 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 484.0
HKD1_k127_2304927_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 328.0
HKD1_k127_2304927_3 MafB19-like deaminase - - - 0.00000000000000000000000000000000000000000000000000000002588 202.0
HKD1_k127_2304927_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000004044 199.0
HKD1_k127_2304927_5 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000000000000000000005113 198.0
HKD1_k127_2320352_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.381e-234 732.0
HKD1_k127_2320352_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 594.0
HKD1_k127_2320352_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000002425 198.0
HKD1_k127_2320352_3 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000008863 181.0
HKD1_k127_2320352_4 - - - - 0.0000000000000000000000002181 112.0
HKD1_k127_2320352_5 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000004551 72.0
HKD1_k127_2350230_0 - - - - 1.054e-240 769.0
HKD1_k127_2350230_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K19707 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 378.0
HKD1_k127_2350230_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 356.0
HKD1_k127_2350230_3 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 316.0
HKD1_k127_2350230_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000000000000995 194.0
HKD1_k127_2350230_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000002124 196.0
HKD1_k127_2350230_6 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000007888 128.0
HKD1_k127_2386299_0 cobalt chelatase K09883 - 6.6.1.2 6.892e-284 883.0
HKD1_k127_2386299_1 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 6.282e-197 616.0
HKD1_k127_2386299_2 Transporter associated domain K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 450.0
HKD1_k127_2386299_3 heat shock protein DnaJ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000959 297.0
HKD1_k127_2386299_4 Belongs to the BolA IbaG family K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.000000000000000000000000000000001617 137.0
HKD1_k127_2386299_5 Esterase-like activity of phytase - - - 0.0000004895 55.0
HKD1_k127_2402317_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1369.0
HKD1_k127_2402317_1 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0 1086.0
HKD1_k127_2402317_10 Domain of Unknown Function (DUF930) - - - 0.000000000000000000000000000000000001085 144.0
HKD1_k127_2402317_11 Phasin protein - - - 0.0000000000000000000006401 101.0
HKD1_k127_2402317_12 sequence-specific DNA binding - - - 0.000000000000000000003727 102.0
HKD1_k127_2402317_13 Tetratricopeptide repeat - - - 0.000005767 57.0
HKD1_k127_2402317_2 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 2.024e-217 680.0
HKD1_k127_2402317_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 543.0
HKD1_k127_2402317_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 317.0
HKD1_k127_2402317_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 300.0
HKD1_k127_2402317_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001412 239.0
HKD1_k127_2402317_7 Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000001918 217.0
HKD1_k127_2402317_8 Domain of unknown function (DUF4167) - - - 0.000000000000000000000000000000000000000000001565 175.0
HKD1_k127_2402317_9 - - - - 0.00000000000000000000000000000000000001442 147.0
HKD1_k127_244825_0 Signal transduction histidine kinase K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 1.018e-288 905.0
HKD1_k127_244825_1 Sigma-54 interaction domain K13599 - - 6.297e-261 810.0
HKD1_k127_244825_2 Sigma-54 interaction domain K07712 - - 2.506e-198 621.0
HKD1_k127_244825_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 595.0
HKD1_k127_244825_4 branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 373.0
HKD1_k127_244825_5 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 367.0
HKD1_k127_244825_6 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000002068 156.0
HKD1_k127_244825_7 EF-hand, calcium binding motif - - - 0.00000000000000000000000000000000000000003411 155.0
HKD1_k127_2477338_0 DEAD/H associated K03724 - - 0.0 1173.0
HKD1_k127_2477338_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 422.0
HKD1_k127_2477338_2 Sel1-like repeats. K07126,K13582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 382.0
HKD1_k127_2477338_3 ICC-like phosphoesterases K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 362.0
HKD1_k127_2477338_4 Putative transmembrane protein (Alph_Pro_TM) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002097 264.0
HKD1_k127_2477338_5 - - - - 0.00000000000000000005722 96.0
HKD1_k127_2477338_6 - - - - 0.000000000002945 68.0
HKD1_k127_2489812_0 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 533.0
HKD1_k127_2489812_1 Domain of unknown function (4846) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 334.0
HKD1_k127_2489812_2 Protein of unknown function (DUF1489) - - - 0.0000000000000000000006317 96.0
HKD1_k127_2513827_0 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 532.0
HKD1_k127_2513827_1 Acetyltransferase (GNAT) domain K22310 - 2.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 460.0
HKD1_k127_2513827_2 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 454.0
HKD1_k127_2513827_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 455.0
HKD1_k127_2513827_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 318.0
HKD1_k127_2513827_5 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000003119 221.0
HKD1_k127_2513827_6 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000006324 136.0
HKD1_k127_2513827_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000001231 59.0
HKD1_k127_2513852_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0 1381.0
HKD1_k127_2513852_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1209.0
HKD1_k127_2513852_10 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 396.0
HKD1_k127_2513852_11 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 320.0
HKD1_k127_2513852_12 Scaffold protein Nfu NifU - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 310.0
HKD1_k127_2513852_13 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 293.0
HKD1_k127_2513852_14 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000116 238.0
HKD1_k127_2513852_15 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000009752 214.0
HKD1_k127_2513852_16 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000001527 206.0
HKD1_k127_2513852_17 chlorophyll binding K03286 - - 0.000000000000000000000000000000000000000000000000000000001582 213.0
HKD1_k127_2513852_18 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000003627 195.0
HKD1_k127_2513852_19 Glycoprotease family K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000000005481 181.0
HKD1_k127_2513852_2 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1186.0
HKD1_k127_2513852_20 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000002696 158.0
HKD1_k127_2513852_21 SPW repeat - - - 0.0000000000000000000000009479 108.0
HKD1_k127_2513852_22 - - - - 0.00000000000000000000005866 102.0
HKD1_k127_2513852_23 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000001058 63.0
HKD1_k127_2513852_24 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000002753 61.0
HKD1_k127_2513852_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 6.317e-223 702.0
HKD1_k127_2513852_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 1.766e-212 665.0
HKD1_k127_2513852_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 608.0
HKD1_k127_2513852_6 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 580.0
HKD1_k127_2513852_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 557.0
HKD1_k127_2513852_8 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 534.0
HKD1_k127_2513852_9 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 414.0
HKD1_k127_2638923_0 glucose-6-phosphate isomerase activity K01810 - 5.3.1.9 3.161e-244 764.0
HKD1_k127_2638923_1 50S ribosome-binding GTPase K06946 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 515.0
HKD1_k127_2638923_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 463.0
HKD1_k127_2638923_3 50S ribosome-binding GTPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 435.0
HKD1_k127_2638923_4 Protein of unknown function (DUF1097) - - - 0.0000000000000000000000000000000000000000000000000747 183.0
HKD1_k127_2638923_5 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.0000000000000002059 82.0
HKD1_k127_2641148_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 581.0
HKD1_k127_2641148_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 571.0
HKD1_k127_2641148_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 567.0
HKD1_k127_2641148_3 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 524.0
HKD1_k127_2641148_4 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 389.0
HKD1_k127_2641148_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000203 202.0
HKD1_k127_2641148_6 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000003977 149.0
HKD1_k127_2641148_7 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000006943 138.0
HKD1_k127_2641148_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000788 116.0
HKD1_k127_2641148_9 Flavin containing amine oxidoreductase - - - 0.0000001802 53.0
HKD1_k127_2642193_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 372.0
HKD1_k127_2642193_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 324.0
HKD1_k127_2642193_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 299.0
HKD1_k127_2642193_3 Chase2 domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003458 282.0
HKD1_k127_2663275_0 Protein of unknown function - - - 1.46e-291 922.0
HKD1_k127_2663275_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 1.284e-203 641.0
HKD1_k127_2663275_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 440.0
HKD1_k127_2663275_3 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 419.0
HKD1_k127_2663275_4 Aminotransferase class-V K04487 GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 416.0
HKD1_k127_2663275_5 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 334.0
HKD1_k127_2663275_6 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000006356 161.0
HKD1_k127_2663275_7 assembly protein K09014 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000003439 84.0
HKD1_k127_2728159_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 548.0
HKD1_k127_2728159_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 507.0
HKD1_k127_2728159_2 OmpW family K07275 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 327.0
HKD1_k127_2728159_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768,K09565 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009191 280.0
HKD1_k127_2728159_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000004802 248.0
HKD1_k127_2728159_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000001068 237.0
HKD1_k127_2728159_6 Putative inner membrane exporter, YdcZ K09936 - - 0.000000000000000000000000000000000000000000000003765 177.0
HKD1_k127_2728159_7 lactoylglutathione lyase activity - - - 0.000000000000000000000002892 107.0
HKD1_k127_2728159_8 Protein of unknown function (DUF423) - - - 0.000000000000000007688 88.0
HKD1_k127_2743928_0 E1 component K00164 - 1.2.4.2 0.0 1163.0
HKD1_k127_2743928_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 567.0
HKD1_k127_2743928_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000905 108.0
HKD1_k127_2751936_0 Glycine cleavage T-protein C-terminal barrel domain K00302,K22086 - 1.5.3.1,1.5.99.5 0.0 1022.0
HKD1_k127_2751936_1 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 358.0
HKD1_k127_2751936_2 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 290.0
HKD1_k127_2751936_3 Sarcosine oxidase, gamma subunit K00305,K22087 - 1.5.3.1,1.5.99.5 0.00000000000000000000000000000000006639 144.0
HKD1_k127_275419_0 Domain of unknown function (DUF1974) K06445 - - 0.0 1232.0
HKD1_k127_275419_1 Belongs to the enoyl-CoA hydratase isomerase family K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 3.184e-304 945.0
HKD1_k127_275419_2 Methylase involved in ubiquinone menaquinone biosynthesis K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000793 149.0
HKD1_k127_275419_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000004954 134.0
HKD1_k127_275419_4 Cytochrome c - - - 0.00000001489 63.0
HKD1_k127_275419_5 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000001283 53.0
HKD1_k127_275419_6 signal peptide protein - - - 0.0001065 50.0
HKD1_k127_280270_0 Tetratricopeptide repeat K03671,K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 424.0
HKD1_k127_280270_1 plasmid maintenance K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 419.0
HKD1_k127_280270_2 peptidase S16 K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 339.0
HKD1_k127_280270_3 YbaK prolyl-tRNA synthetase associated K19055 - - 0.00000000000000000000000000000000000000000000000000000000000000008361 225.0
HKD1_k127_280270_4 LemA family K03744 - - 0.0000000000000000000000000000000000001942 143.0
HKD1_k127_280270_5 Belongs to the UPF0434 family K09791 - - 0.00000000000000000002963 97.0
HKD1_k127_2803844_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 5.786e-276 854.0
HKD1_k127_2803844_1 Peptidase family M3 K01284 GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 4.949e-224 703.0
HKD1_k127_2803844_2 Fic/DOC family N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 441.0
HKD1_k127_2803844_3 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007686 270.0
HKD1_k127_287498_0 Glycosyl hydrolases family 15 - - - 6.231e-282 877.0
HKD1_k127_287498_1 N-terminal domain of (some) glycogen debranching enzymes - - - 1.717e-255 807.0
HKD1_k127_287498_2 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 597.0
HKD1_k127_287498_3 ABC transporter transmembrane region K06147,K18893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 485.0
HKD1_k127_287498_4 TIGRFAM type I secretion membrane fusion protein, HlyD family K02022 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 311.0
HKD1_k127_287498_5 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000004088 247.0
HKD1_k127_287498_6 - - - - 0.0000000004921 60.0
HKD1_k127_287498_7 - - - - 0.000001036 57.0
HKD1_k127_299865_0 B12 binding domain - - - 2.974e-214 677.0
HKD1_k127_299865_1 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 376.0
HKD1_k127_299865_2 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 350.0
HKD1_k127_299865_3 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008059 270.0
HKD1_k127_299865_4 - - - - 0.0003329 49.0
HKD1_k127_3021385_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1781.0
HKD1_k127_3021385_1 Helicase K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.0 1090.0
HKD1_k127_3021385_10 glutamate-ammonia ligase activity - - - 0.000000000000000000000002372 114.0
HKD1_k127_3021385_11 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000009209 103.0
HKD1_k127_3021385_13 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.00000000001355 68.0
HKD1_k127_3021385_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1009.0
HKD1_k127_3021385_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 8.377e-194 613.0
HKD1_k127_3021385_4 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 562.0
HKD1_k127_3021385_5 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 411.0
HKD1_k127_3021385_6 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 353.0
HKD1_k127_3021385_8 cell septum assembly - - - 0.0000000000000000000000000000000000000006405 165.0
HKD1_k127_3021385_9 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000002354 122.0
HKD1_k127_3045400_0 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 1.637e-252 791.0
HKD1_k127_3045400_1 Protein of unknown function (DUF3754) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 600.0
HKD1_k127_3045400_2 ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 322.0
HKD1_k127_3045400_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000002147 243.0
HKD1_k127_3045400_4 Heat shock protein DnaJ domain protein K05516 - - 0.0000000000000000000000000000000000000000001257 177.0
HKD1_k127_3045400_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000001384 87.0
HKD1_k127_3045400_6 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00001248 47.0
HKD1_k127_3058905_0 MMPL family K07003 - - 0.0 1086.0
HKD1_k127_3058905_1 Belongs to the aldehyde dehydrogenase family K00135 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019752,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 316.0
HKD1_k127_3058905_2 Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000003566 256.0
HKD1_k127_306341_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11103 - - 7.291e-196 618.0
HKD1_k127_306341_1 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 344.0
HKD1_k127_306341_2 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000009607 47.0
HKD1_k127_3069792_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1428.0
HKD1_k127_3069792_1 Protein of unknown function, DUF255 K06888 - - 3.176e-292 924.0
HKD1_k127_3069792_10 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 389.0
HKD1_k127_3069792_11 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 338.0
HKD1_k127_3069792_12 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 309.0
HKD1_k127_3069792_13 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000001316 269.0
HKD1_k127_3069792_14 Lipopolysaccharide-assembly K03643 - - 0.000000000000000000000000000000000000000000000001015 181.0
HKD1_k127_3069792_15 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000003983 168.0
HKD1_k127_3069792_16 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000000001252 126.0
HKD1_k127_3069792_17 protein conserved in bacteria - - - 0.000000000000000001775 92.0
HKD1_k127_3069792_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.293e-286 893.0
HKD1_k127_3069792_3 Aminotransferase class I and II K14261,K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 567.0
HKD1_k127_3069792_4 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 539.0
HKD1_k127_3069792_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 514.0
HKD1_k127_3069792_6 Pantothenic acid kinase K00867 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 488.0
HKD1_k127_3069792_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 433.0
HKD1_k127_3069792_8 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 424.0
HKD1_k127_3069792_9 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 386.0
HKD1_k127_3071344_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 6.612e-224 701.0
HKD1_k127_3071344_1 DnaJ-class molecular chaperone K05516 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 451.0
HKD1_k127_3071344_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 426.0
HKD1_k127_3071344_3 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 419.0
HKD1_k127_3071344_4 TraB family K09973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 346.0
HKD1_k127_3071344_5 excinuclease ABC activity - - - 0.00000000000000000000000001062 116.0
HKD1_k127_3071344_6 MerR HTH family regulatory protein K18997 - - 0.000000000000000000003927 96.0
HKD1_k127_3072108_0 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 503.0
HKD1_k127_3072108_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 402.0
HKD1_k127_3072108_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000001888 120.0
HKD1_k127_3072108_3 Domain of unknown function (DUF1476) - - - 0.000000000000002608 76.0
HKD1_k127_3072108_4 - - - - 0.000000000839 68.0
HKD1_k127_3086619_0 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 445.0
HKD1_k127_3086619_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788,K07789 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 341.0
HKD1_k127_3086619_2 Putative DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002439 274.0
HKD1_k127_3086619_3 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000004692 211.0
HKD1_k127_3086619_4 - - - - 0.000000000000000000000000000002587 123.0
HKD1_k127_3086619_5 Protein of unknown function (DUF1109) - - - 0.0000000000000000000003 102.0
HKD1_k127_3129882_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0 1448.0
HKD1_k127_3129882_1 de-polymerase K05973 - 3.1.1.75 1.147e-198 628.0
HKD1_k127_3129882_2 AsmA-like C-terminal region K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 302.0
HKD1_k127_3129882_3 Acyltransferase family - - - 0.0000000000000000000000000000000000000000001418 171.0
HKD1_k127_3129882_4 Phospholipid methyltransferase - - - 0.000000000000000000000000000000008239 132.0
HKD1_k127_3129882_5 cytochrome K08738 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015979,GO:0016020,GO:0044237,GO:0044464,GO:0071944 - 0.00000000000000000000839 93.0
HKD1_k127_3129882_7 cytochrome K08738 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015979,GO:0016020,GO:0044237,GO:0044464,GO:0071944 - 0.0000003463 54.0
HKD1_k127_3129882_9 Acyltransferase family - - - 0.0000058 54.0
HKD1_k127_3142636_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1224.0
HKD1_k127_3142636_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1185.0
HKD1_k127_3142636_10 Pentapeptide repeat protein K15352 - - 0.000000000000000000000000000000000000000000005717 178.0
HKD1_k127_3142636_11 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000001696 151.0
HKD1_k127_3142636_13 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000006632 141.0
HKD1_k127_3142636_14 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000017 111.0
HKD1_k127_3142636_2 Participates in both transcription termination and antitermination K02600 - - 4.811e-194 610.0
HKD1_k127_3142636_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 441.0
HKD1_k127_3142636_4 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 357.0
HKD1_k127_3142636_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 311.0
HKD1_k127_3142636_6 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 307.0
HKD1_k127_3142636_7 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002796 276.0
HKD1_k127_3142636_8 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000000000000000000000000000000000000000000001799 222.0
HKD1_k127_3142636_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000000000004231 196.0
HKD1_k127_3156778_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1143.0
HKD1_k127_3156778_1 Belongs to the beta-ketoacyl-ACP synthases family K00647 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 1.769e-223 696.0
HKD1_k127_3156778_10 Bacterial SH3 domain homologues K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000006034 246.0
HKD1_k127_3156778_11 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000008512 237.0
HKD1_k127_3156778_12 Belongs to the Fur family K09826 - - 0.00000000000000000000000000000000000000000000000000000000000415 212.0
HKD1_k127_3156778_13 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000005715 201.0
HKD1_k127_3156778_14 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000001541 188.0
HKD1_k127_3156778_16 Domain of unknown function (DUF4189) - - - 0.0000002353 59.0
HKD1_k127_3156778_2 D-isomer specific 2-hydroxyacid dehydrogenase K00015 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 598.0
HKD1_k127_3156778_3 Cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 559.0
HKD1_k127_3156778_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038,K21977 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 538.0
HKD1_k127_3156778_5 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 531.0
HKD1_k127_3156778_6 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 476.0
HKD1_k127_3156778_7 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 423.0
HKD1_k127_3156778_8 UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 385.0
HKD1_k127_3156778_9 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 314.0
HKD1_k127_3191776_0 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 424.0
HKD1_k127_3191776_1 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 394.0
HKD1_k127_3191776_2 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 339.0
HKD1_k127_3191776_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 300.0
HKD1_k127_3191776_4 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002344 261.0
HKD1_k127_3191776_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000003504 246.0
HKD1_k127_3191776_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000006834 248.0
HKD1_k127_3191776_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001303 231.0
HKD1_k127_3191776_8 - - - - 0.0000000000000000000000004149 113.0
HKD1_k127_3191776_9 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0007838 48.0
HKD1_k127_3193181_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 5.551e-263 821.0
HKD1_k127_3193181_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 590.0
HKD1_k127_3193181_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000002549 78.0
HKD1_k127_3193181_2 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 527.0
HKD1_k127_3193181_3 Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 432.0
HKD1_k127_3193181_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 334.0
HKD1_k127_3193181_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 326.0
HKD1_k127_3193181_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 303.0
HKD1_k127_3193181_7 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003291 244.0
HKD1_k127_3193181_8 Belongs to the HesB IscA family K13628,K15724 - - 0.0000000000000000000000000000000000000000001592 162.0
HKD1_k127_3193181_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.0000000000000000000281 96.0
HKD1_k127_3196768_0 Carbamoyl-phosphate synthase L chain ATP-binding K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 3.319e-297 917.0
HKD1_k127_3196768_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 346.0
HKD1_k127_3196768_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 316.0
HKD1_k127_3196768_3 - - - - 0.0000000000000000000000000001473 119.0
HKD1_k127_3196768_4 periplasmic protein - - - 0.000000000000000000002295 107.0
HKD1_k127_3196768_5 YARHG - - - 0.0000000000004087 75.0
HKD1_k127_3196768_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000003662 60.0
HKD1_k127_3203422_0 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007197 267.0
HKD1_k127_3212596_0 ABC transporter K06147,K18893 - - 1.65e-245 774.0
HKD1_k127_3212596_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.268e-229 713.0
HKD1_k127_3212596_2 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 563.0
HKD1_k127_3212596_3 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 516.0
HKD1_k127_3212596_4 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 454.0
HKD1_k127_3212596_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 369.0
HKD1_k127_3212596_6 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008048 231.0
HKD1_k127_3212596_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000002262 117.0
HKD1_k127_3212596_8 - - - - 0.0000000000000000001915 100.0
HKD1_k127_3212596_9 Outer membrane protein beta-barrel domain K16079 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000001936 76.0
HKD1_k127_3229637_0 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 0.0 1120.0
HKD1_k127_3229637_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 4.396e-293 914.0
HKD1_k127_3229637_10 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 458.0
HKD1_k127_3229637_11 NLP P60 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 391.0
HKD1_k127_3229637_12 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 379.0
HKD1_k127_3229637_13 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 363.0
HKD1_k127_3229637_14 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 342.0
HKD1_k127_3229637_15 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 293.0
HKD1_k127_3229637_16 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001557 271.0
HKD1_k127_3229637_17 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001804 261.0
HKD1_k127_3229637_18 Glycosyl transferases group 1 K21011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002046 259.0
HKD1_k127_3229637_19 Phosphatidylethanolamine-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004418 255.0
HKD1_k127_3229637_2 Extracellular solute-binding protein K13893 - - 1.141e-283 882.0
HKD1_k127_3229637_20 Protein of unknown function (DUF779) K09959 - - 0.000000000000000000000000000000000000000000000000000000001054 205.0
HKD1_k127_3229637_21 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.000000000000000000000000000000000000000000000000000002908 196.0
HKD1_k127_3229637_22 Cytochrome c K08738 - - 0.000000000000000000000000000000000000000000000002755 179.0
HKD1_k127_3229637_23 - - - - 0.00000000000000000000000000000000000000003474 159.0
HKD1_k127_3229637_24 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000002637 150.0
HKD1_k127_3229637_26 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000002042 53.0
HKD1_k127_3229637_3 belongs to the aldehyde dehydrogenase family K00138 - - 1.429e-271 844.0
HKD1_k127_3229637_4 Belongs to the ABC transporter superfamily K02031,K02032,K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 4.388e-266 827.0
HKD1_k127_3229637_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 5.905e-233 734.0
HKD1_k127_3229637_6 biosynthesis protein - GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192 - 2.574e-226 721.0
HKD1_k127_3229637_7 binding-protein-dependent transport systems inner membrane component K13894 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 601.0
HKD1_k127_3229637_8 Binding-protein-dependent transport system inner membrane component K13895 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 602.0
HKD1_k127_3229637_9 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 574.0
HKD1_k127_3235669_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 1.962e-201 637.0
HKD1_k127_3235669_1 penicillin-binding protein K03587 - 3.4.16.4 2.034e-195 625.0
HKD1_k127_3235669_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 413.0
HKD1_k127_3235669_3 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003983 267.0
HKD1_k127_3235669_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001493 260.0
HKD1_k127_3235669_5 Dihydrofolate reductase K17364 - 1.5.1.47 0.000000000000000000000000000000000000000000000000000000000000302 214.0
HKD1_k127_3235669_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000003671 208.0
HKD1_k127_3235669_7 - - - - 0.0000000000000000000001476 102.0
HKD1_k127_3235669_8 Lipase maturation factor - - - 0.00000000000000000004498 89.0
HKD1_k127_3235669_9 - - - - 0.0000000000000000008793 91.0
HKD1_k127_3431741_0 Cupin K01569 - 4.1.1.2 2.032e-204 644.0
HKD1_k127_3431741_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 538.0
HKD1_k127_3431741_2 two component transcriptional regulator K02483,K13584 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 451.0
HKD1_k127_3431741_3 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 340.0
HKD1_k127_3431741_4 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 327.0
HKD1_k127_3431741_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001153 239.0
HKD1_k127_3431741_6 Protein of unknown function (DUF1153) - - - 0.000000000000000000000000000000000000000000000000000103 187.0
HKD1_k127_3431741_7 flagellar export protein FliJ - - - 0.00000000000000000000000000000000000000001197 157.0
HKD1_k127_343835_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380 - 1.8.1.2 2.62e-288 895.0
HKD1_k127_343835_1 Nitrite and sulphite reductase 4Fe-4S domain K00381,K00392 - 1.8.1.2,1.8.7.1 2.936e-288 899.0
HKD1_k127_343835_10 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 450.0
HKD1_k127_343835_11 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06136,K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 436.0
HKD1_k127_343835_12 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 426.0
HKD1_k127_343835_13 Belongs to the RimK family K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 385.0
HKD1_k127_343835_14 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 391.0
HKD1_k127_343835_15 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 377.0
HKD1_k127_343835_16 TIGRFAM beta-ribofuranosylaminobenzene 5'-phosphate synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 382.0
HKD1_k127_343835_17 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 357.0
HKD1_k127_343835_18 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 351.0
HKD1_k127_343835_19 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 360.0
HKD1_k127_343835_2 biosynthesis protein E K06139 - - 6.844e-204 642.0
HKD1_k127_343835_20 Cold-shock K03704 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008627 339.0
HKD1_k127_343835_21 PFAM Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 331.0
HKD1_k127_343835_22 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 332.0
HKD1_k127_343835_23 ATP-grasp domain K06913 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008531 329.0
HKD1_k127_343835_24 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 310.0
HKD1_k127_343835_25 TIGRFAM H4MPT-linked C1 transfer pathway protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 311.0
HKD1_k127_343835_26 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 309.0
HKD1_k127_343835_27 Protein of unknown function (DUF447) K09154 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 285.0
HKD1_k127_343835_28 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000002118 276.0
HKD1_k127_343835_29 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000003787 244.0
HKD1_k127_343835_3 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 6.983e-204 648.0
HKD1_k127_343835_30 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000008041 243.0
HKD1_k127_343835_31 Pfam:DUF556 - - - 0.00000000000000000000000000000000000000000000000000000000000002709 222.0
HKD1_k127_343835_32 COG0607 Rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000000003104 216.0
HKD1_k127_343835_33 PFAM aspartate glutamate uridylate kinase - - - 0.00000000000000000000000000000000000000000000000000000005543 207.0
HKD1_k127_343835_34 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000000000000002709 184.0
HKD1_k127_343835_35 - - - - 0.0000000000000000000000000000000000000000015 165.0
HKD1_k127_343835_36 Cytochrome c K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000001768 152.0
HKD1_k127_343835_37 Coenzyme PQQ synthesis protein D (PqqD) K06138 - - 0.000000000000000000000000000000000001461 143.0
HKD1_k127_343835_38 Protein of unknown function (DUF2380) - - - 0.000000000000000000000000000000002932 135.0
HKD1_k127_343835_39 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000002637 117.0
HKD1_k127_343835_4 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 578.0
HKD1_k127_343835_41 Uncharacterized ACR, COG1430 K09005 - - 0.00000001819 63.0
HKD1_k127_343835_5 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 524.0
HKD1_k127_343835_6 Sulfate adenylyltransferase K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 515.0
HKD1_k127_343835_7 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 509.0
HKD1_k127_343835_8 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 488.0
HKD1_k127_343835_9 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal K10714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 463.0
HKD1_k127_3497541_0 succinylglutamate desuccinylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 376.0
HKD1_k127_3497541_1 - - - - 0.000000000000000000000000000000000000000009788 160.0
HKD1_k127_3497541_2 AsmA-like C-terminal region K07289 - - 0.0000000000000000001321 104.0
HKD1_k127_3503873_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 612.0
HKD1_k127_3503873_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 369.0
HKD1_k127_3503873_2 probably involved in intracellular septation K06190 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 294.0
HKD1_k127_3503873_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007373 276.0
HKD1_k127_3503873_4 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001105 262.0
HKD1_k127_3503873_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007445 226.0
HKD1_k127_3526392_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.715e-253 793.0
HKD1_k127_3526392_1 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 7.98e-220 686.0
HKD1_k127_3526392_10 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000000000000000000001172 187.0
HKD1_k127_3526392_11 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000001404 164.0
HKD1_k127_3526392_12 Phosphopantetheine attachment site K02078,K14661 - - 0.0000000000000000000000000000000000000006862 150.0
HKD1_k127_3526392_14 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000002037 147.0
HKD1_k127_3526392_15 Rdx family K07401 - - 0.0000000000000000000000000000000004247 134.0
HKD1_k127_3526392_17 Protein of unknown function (DUF1236) - - - 0.00000000000000000005817 102.0
HKD1_k127_3526392_19 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000004449 68.0
HKD1_k127_3526392_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 413.0
HKD1_k127_3526392_3 Chalcone and stilbene synthases, C-terminal domain K16167 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 408.0
HKD1_k127_3526392_4 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 358.0
HKD1_k127_3526392_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 324.0
HKD1_k127_3526392_6 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002132 245.0
HKD1_k127_3526392_7 Isoprenylcysteine carboxyl methyltransferase K16168 - - 0.00000000000000000000000000000000000000000000000000000000000004188 222.0
HKD1_k127_3526392_8 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000004774 223.0
HKD1_k127_3526392_9 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000002045 212.0
HKD1_k127_3528863_0 Thiol oxidoreductase - - - 8.675e-219 690.0
HKD1_k127_3528863_1 Choloylglycine hydrolase K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 440.0
HKD1_k127_3528863_2 Imelysin K07231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 407.0
HKD1_k127_3542686_0 Cellulose synthase K00694 - 2.4.1.12 7.108e-263 824.0
HKD1_k127_3542686_1 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 570.0
HKD1_k127_3542686_2 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 513.0
HKD1_k127_3542686_3 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 470.0
HKD1_k127_3542686_4 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 429.0
HKD1_k127_3542686_5 D-arabinono-1,4-lactone oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 366.0
HKD1_k127_3542686_6 COG0845 membrane-fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 321.0
HKD1_k127_3542686_7 ATP dependent DNA ligase C terminal region K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000003372 254.0
HKD1_k127_3542686_8 PFAM Transglycosylase-associated protein - - - 0.0000000000000000004591 89.0
HKD1_k127_3542686_9 NAD(P)H-binding - - - 0.00000006238 55.0
HKD1_k127_358385_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1828.0
HKD1_k127_358385_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008098 253.0
HKD1_k127_358385_3 - - - - 0.0000000000000000000000004039 109.0
HKD1_k127_3608177_0 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 489.0
HKD1_k127_3608177_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03215 - 2.1.1.190,2.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 451.0
HKD1_k127_3608177_2 PFAM ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000001453 228.0
HKD1_k127_3614128_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 6.029e-235 736.0
HKD1_k127_3614128_1 Cyclic nucleotide-monophosphate binding domain K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 552.0
HKD1_k127_3614128_10 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 334.0
HKD1_k127_3614128_11 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 310.0
HKD1_k127_3614128_12 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 315.0
HKD1_k127_3614128_13 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 310.0
HKD1_k127_3614128_14 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000518 266.0
HKD1_k127_3614128_15 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001166 236.0
HKD1_k127_3614128_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000008288 218.0
HKD1_k127_3614128_17 Pyroglutamyl peptidase K01304 - 3.4.19.3 0.00000000000000000000000000000000000000000000008581 178.0
HKD1_k127_3614128_18 protein tyrosine phosphatase - - - 0.00000000000000000000000000000000000000000183 162.0
HKD1_k127_3614128_19 transcriptional regulator K13771,K13772 - - 0.000000000000000000000000000000000000001367 153.0
HKD1_k127_3614128_2 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 503.0
HKD1_k127_3614128_20 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000000000001461 122.0
HKD1_k127_3614128_21 Transglycosylase associated protein - - - 0.00000000000000000000000003123 113.0
HKD1_k127_3614128_23 - - - - 0.00000000000000000001105 96.0
HKD1_k127_3614128_24 - - - - 0.0000000000000000005438 91.0
HKD1_k127_3614128_28 PFAM Tetratricopeptide repeat - - - 0.00000009081 66.0
HKD1_k127_3614128_29 BA14K-like protein - - - 0.0002984 50.0
HKD1_k127_3614128_3 Major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 505.0
HKD1_k127_3614128_30 Flp Fap pilin component K02651 - - 0.0008573 46.0
HKD1_k127_3614128_4 Protein conserved in bacteria K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 505.0
HKD1_k127_3614128_5 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 481.0
HKD1_k127_3614128_6 ABC transporter permease K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 475.0
HKD1_k127_3614128_7 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 434.0
HKD1_k127_3614128_8 Histidyl-tRNA synthetase K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 415.0
HKD1_k127_3614128_9 Fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 394.0
HKD1_k127_3670707_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase K03606,K20997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008573 606.0
HKD1_k127_3670707_1 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 412.0
HKD1_k127_3670707_2 Protein of unknown function (DUF1513) K09947 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 394.0
HKD1_k127_3670707_3 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 379.0
HKD1_k127_3670707_4 Imelysin K07231 - - 0.000000000000000000000000000000000000000000000000000000000000001175 223.0
HKD1_k127_3670707_5 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000003511 201.0
HKD1_k127_3670707_6 Imelysin K07338 - - 0.000000000000000000000000676 117.0
HKD1_k127_3724932_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 468.0
HKD1_k127_3724932_1 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 384.0
HKD1_k127_3724932_2 Belongs to the Fur family K09823 - - 0.00000000000000000000000000000000000000000000000000000000000000008731 225.0
HKD1_k127_3724932_3 extracellular polysaccharide biosynthetic process K16554 - - 0.0000000000000000000000000000000000000509 147.0
HKD1_k127_3724932_4 ABC-type Mn2 Zn2 transport systems permease components K09816 - - 0.00001578 52.0
HKD1_k127_377243_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 3.06e-223 697.0
HKD1_k127_377243_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 472.0
HKD1_k127_377243_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 418.0
HKD1_k127_377243_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 387.0
HKD1_k127_377243_4 Domain of unknown function (DUF1732) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 321.0
HKD1_k127_377243_5 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000007439 267.0
HKD1_k127_377243_6 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000006821 240.0
HKD1_k127_377243_7 PFAM short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000003565 192.0
HKD1_k127_377243_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000731 153.0
HKD1_k127_377243_9 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000001388 71.0
HKD1_k127_3784260_0 Putative transposase - - - 5.808e-237 735.0
HKD1_k127_3784260_1 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 542.0
HKD1_k127_3784260_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000005223 145.0
HKD1_k127_3814522_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0 1148.0
HKD1_k127_3814522_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 6.646e-248 772.0
HKD1_k127_3814522_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 580.0
HKD1_k127_3814522_3 MAPEG family - - - 0.00000000000000000000000000000000000000000002713 165.0
HKD1_k127_3814522_4 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000006804 157.0
HKD1_k127_3814522_5 Bacterial protein of unknown function (DUF937) - - - 0.000000000000255 71.0
HKD1_k127_3903860_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 318.0
HKD1_k127_3903860_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000001036 213.0
HKD1_k127_3903860_2 AcrB/AcrD/AcrF family - - - 0.0000000002066 65.0
HKD1_k127_4020376_0 FAD binding domain K00480 - 1.14.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 383.0
HKD1_k127_4020376_1 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009875 351.0
HKD1_k127_4020376_2 Extensin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 290.0
HKD1_k127_4020376_3 Zinc-finger domain - - - 0.0000000000000000000000000000000000001338 142.0
HKD1_k127_4020376_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000001817 79.0
HKD1_k127_4020376_5 WHG domain - - - 0.00000174 51.0
HKD1_k127_4024032_0 Participates in both transcription termination and antitermination K02600 - - 1.756e-222 694.0
HKD1_k127_4024032_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 284.0
HKD1_k127_4024032_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000097 257.0
HKD1_k127_4024032_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000001223 118.0
HKD1_k127_4024032_4 - - - - 0.000008248 57.0
HKD1_k127_4028009_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.52e-211 672.0
HKD1_k127_4028009_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 295.0
HKD1_k127_4028009_2 Copper resistance protein D K07245 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 291.0
HKD1_k127_4028009_3 conserved protein UCP033924 - - - 0.000000000000000000000000000000000000000000000008196 179.0
HKD1_k127_4028009_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.000000000000000000000000000000000000000000002062 165.0
HKD1_k127_4028009_6 CopC domain K07156 - - 0.00000000000000000000000000004168 120.0
HKD1_k127_4028009_7 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000006313 96.0
HKD1_k127_4030731_0 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 491.0
HKD1_k127_4030731_1 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001046 247.0
HKD1_k127_4030731_2 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000000000000000000001114 224.0
HKD1_k127_4030731_3 Electron transfer flavoprotein, alpha subunit K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000001179 219.0
HKD1_k127_4030731_4 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000005172 233.0
HKD1_k127_4030731_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000005116 190.0
HKD1_k127_4030731_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000006691 150.0
HKD1_k127_4030731_7 Bacterial protein of unknown function (DUF899) - - - 0.0000000002002 62.0
HKD1_k127_4030731_8 Anti-sigma-K factor rskA - - - 0.0000000006399 61.0
HKD1_k127_4034916_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 519.0
HKD1_k127_4034916_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 469.0
HKD1_k127_4034916_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 375.0
HKD1_k127_4034916_3 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 364.0
HKD1_k127_4034916_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 349.0
HKD1_k127_4034916_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 343.0
HKD1_k127_4034916_6 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 298.0
HKD1_k127_4034916_7 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000002702 146.0
HKD1_k127_4034916_8 asparagine synthase K01953 - 6.3.5.4 0.0000002018 53.0
HKD1_k127_4044643_0 oligoendopeptidase K08602 - - 1.266e-301 934.0
HKD1_k127_4044643_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 4.624e-298 925.0
HKD1_k127_4044643_10 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 340.0
HKD1_k127_4044643_11 Protein of unknown function (DUF1036) - - - 0.00000000000000000000000000000000000000000000000000000000000000002069 227.0
HKD1_k127_4044643_12 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000005837 180.0
HKD1_k127_4044643_13 Belongs to the UPF0335 family - - - 0.000000000000000000000000000000007261 131.0
HKD1_k127_4044643_15 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000003401 75.0
HKD1_k127_4044643_16 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000002768 75.0
HKD1_k127_4044643_17 Protein of unknown function (DUF2892) - - - 0.0000000000006306 71.0
HKD1_k127_4044643_18 membrane protein (DUF2078) K08982 - - 0.00000000002985 66.0
HKD1_k127_4044643_2 Sigma-54 interaction domain - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 3.444e-256 799.0
HKD1_k127_4044643_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 9.445e-233 727.0
HKD1_k127_4044643_4 ErfK YbiS YcfS YnhG family protein K21470 - - 4.201e-206 657.0
HKD1_k127_4044643_5 unusual protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 602.0
HKD1_k127_4044643_6 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 546.0
HKD1_k127_4044643_7 LysR substrate binding domain K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 449.0
HKD1_k127_4044643_8 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 407.0
HKD1_k127_4044643_9 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 404.0
HKD1_k127_4062088_0 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 472.0
HKD1_k127_4062088_1 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 313.0
HKD1_k127_4062088_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000006131 267.0
HKD1_k127_4062088_3 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000003658 142.0
HKD1_k127_4062088_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000136 59.0
HKD1_k127_4062088_5 PRC-barrel domain - - - 0.0000002249 60.0
HKD1_k127_4107469_0 AMP-binding enzyme C-terminal domain K00666,K02182 - 6.2.1.48 8.513e-292 902.0
HKD1_k127_4107469_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 501.0
HKD1_k127_4107469_10 Small protein - - - 0.0000000000000000004187 88.0
HKD1_k127_4107469_2 Protein of unknown function (DUF1013) K09987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 362.0
HKD1_k127_4107469_3 Alpha/beta hydrolase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 328.0
HKD1_k127_4107469_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000009713 234.0
HKD1_k127_4107469_5 dehydratase K17865 GO:0003674,GO:0003824,GO:0003859,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0046487,GO:0071704 4.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000002145 231.0
HKD1_k127_4107469_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000003408 152.0
HKD1_k127_4107469_7 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000001047 126.0
HKD1_k127_4107469_8 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000002162 124.0
HKD1_k127_4107469_9 Protein of unknown function (DUF465) - - - 0.0000000000000000000005214 96.0
HKD1_k127_4109977_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1504.0
HKD1_k127_4109977_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1417.0
HKD1_k127_4109977_10 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 533.0
HKD1_k127_4109977_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 455.0
HKD1_k127_4109977_12 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 443.0
HKD1_k127_4109977_13 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 362.0
HKD1_k127_4109977_14 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 329.0
HKD1_k127_4109977_15 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 317.0
HKD1_k127_4109977_16 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 307.0
HKD1_k127_4109977_17 Domain of unknown function (DUF1849) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 289.0
HKD1_k127_4109977_18 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001323 271.0
HKD1_k127_4109977_19 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003844 240.0
HKD1_k127_4109977_2 Belongs to the ClpA ClpB family K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1362.0
HKD1_k127_4109977_20 Response regulator receiver K11443 - - 0.000000000000000000000000000000000000000000000000000000000000000006009 227.0
HKD1_k127_4109977_21 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000001968 224.0
HKD1_k127_4109977_22 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000000000000000000000000000005425 216.0
HKD1_k127_4109977_23 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000008576 214.0
HKD1_k127_4109977_24 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000000000001233 199.0
HKD1_k127_4109977_25 Belongs to the EutC family K03736 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0009350,GO:0019842,GO:0031419,GO:0032991,GO:0036094,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0097159,GO:1901363,GO:1902494 4.3.1.7 0.0000000000000000000000000000000000000000000000000000006991 196.0
HKD1_k127_4109977_26 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000001906 193.0
HKD1_k127_4109977_27 Protein of unknown function (DUF983) - - - 0.000000000000000000000000000000000000000000000001901 178.0
HKD1_k127_4109977_28 phasin family - - - 0.00000000000000000000000000000000000000008794 154.0
HKD1_k127_4109977_29 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000009389 143.0
HKD1_k127_4109977_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 2.943e-282 886.0
HKD1_k127_4109977_30 Chorismate mutase, type II K04782 - 4.2.99.21 0.000000000000000000000000000000000388 141.0
HKD1_k127_4109977_31 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000006914 108.0
HKD1_k127_4109977_32 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000002609 105.0
HKD1_k127_4109977_33 mRNA binding K07339 - - 0.000000000000000000000003431 104.0
HKD1_k127_4109977_34 Protein of unknown function (DUF3572) - - - 0.00000000000000000008989 91.0
HKD1_k127_4109977_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 9.382e-277 871.0
HKD1_k127_4109977_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 5.553e-276 854.0
HKD1_k127_4109977_6 Amidohydrolase family K01465 - 3.5.2.3 1.535e-231 732.0
HKD1_k127_4109977_7 response regulator K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 6.854e-205 646.0
HKD1_k127_4109977_8 acyl-CoA dehydrogenase K09456 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008470,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016491,GO:0016627,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0033554,GO:0042802,GO:0043565,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 570.0
HKD1_k127_4109977_9 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 543.0
HKD1_k127_412531_0 Alcohol dehydrogenase zinc-binding K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 442.0
HKD1_k127_412531_1 rrna methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 291.0
HKD1_k127_412531_2 invasion associated locus B - - - 0.00000000000000000000000000000000000000000004412 168.0
HKD1_k127_412531_3 Protein of unknown function (DUF2865) - - - 0.000005984 53.0
HKD1_k127_4154107_0 PFAM ABC transporter K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 362.0
HKD1_k127_4154107_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001682 285.0
HKD1_k127_4154107_2 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001329 254.0
HKD1_k127_4154107_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000008752 228.0
HKD1_k127_4154107_4 Molybdenum ABC transporter K02020 - - 0.00000000000000000000000000000000000000000000000000000118 198.0
HKD1_k127_416334_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 1.25e-199 628.0
HKD1_k127_416334_1 - - - - 0.0000000000000000002549 94.0
HKD1_k127_416334_2 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000004003 79.0
HKD1_k127_4166136_0 MotA/TolQ/ExbB proton channel family K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 387.0
HKD1_k127_4166136_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 394.0
HKD1_k127_4166136_10 Thioesterase-like superfamily K07107 - - 0.000000000000003202 77.0
HKD1_k127_4166136_11 Cysteine rich repeat - - - 0.000002217 57.0
HKD1_k127_4166136_12 - - - - 0.000003242 53.0
HKD1_k127_4166136_2 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 380.0
HKD1_k127_4166136_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 356.0
HKD1_k127_4166136_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 343.0
HKD1_k127_4166136_5 Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000000000000000008535 213.0
HKD1_k127_4166136_6 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000000000000000000000000000000008171 149.0
HKD1_k127_4166136_8 - - - - 0.000000000000000004277 95.0
HKD1_k127_4166136_9 TIGRFAM protein TolA K03646 - - 0.0000000000000004603 83.0
HKD1_k127_4183458_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1047.0
HKD1_k127_4183458_1 TIGRFAM hopanoid biosynthesis associated radical SAM protein HpnJ - - - 6.177e-259 804.0
HKD1_k127_4183458_2 Hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 429.0
HKD1_k127_4183458_3 (Lipo)protein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 364.0
HKD1_k127_4183458_4 PFAM toluene tolerance family protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000406 240.0
HKD1_k127_4194858_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1018.0
HKD1_k127_4194858_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 7.824e-243 754.0
HKD1_k127_4194858_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 310.0
HKD1_k127_4218944_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.844e-207 655.0
HKD1_k127_4218944_1 PQQ-like domain K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 565.0
HKD1_k127_4218944_10 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 294.0
HKD1_k127_4218944_11 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 283.0
HKD1_k127_4218944_12 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004498 275.0
HKD1_k127_4218944_13 Uncharacterised protein family (UPF0014) K02069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001942 261.0
HKD1_k127_4218944_14 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000003549 254.0
HKD1_k127_4218944_15 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000007364 232.0
HKD1_k127_4218944_16 DNA polymerase III chi subunit K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000002362 226.0
HKD1_k127_4218944_17 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000009861 215.0
HKD1_k127_4218944_18 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000000000000000000000004653 171.0
HKD1_k127_4218944_19 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000000000000000002347 169.0
HKD1_k127_4218944_2 Nadh flavin oxidoreductase nadh oxidase K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 498.0
HKD1_k127_4218944_20 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000000005089 155.0
HKD1_k127_4218944_21 MOSC domain - - - 0.0000000000000000000000000000000000000008737 156.0
HKD1_k127_4218944_22 - - - - 0.0000000000000000000000000000000000000022 157.0
HKD1_k127_4218944_23 HNH nucleases - - - 0.0000000000000000000000000000000000003793 148.0
HKD1_k127_4218944_24 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000000000003598 136.0
HKD1_k127_4218944_25 Cold shock K03704 - - 0.00000000000000000000000000000000005717 134.0
HKD1_k127_4218944_27 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000008087 123.0
HKD1_k127_4218944_28 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000001443 126.0
HKD1_k127_4218944_29 Cupredoxin-like domain - - - 0.0000000000000000000000000002657 119.0
HKD1_k127_4218944_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 452.0
HKD1_k127_4218944_30 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.000000000000000000000003225 102.0
HKD1_k127_4218944_31 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000402 112.0
HKD1_k127_4218944_33 COG0457 FOG TPR repeat - - - 0.000000000001931 72.0
HKD1_k127_4218944_34 AAA ATPase domain - - - 0.00000000001187 66.0
HKD1_k127_4218944_35 COG0457 FOG TPR repeat - - - 0.0000000001558 63.0
HKD1_k127_4218944_4 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 422.0
HKD1_k127_4218944_5 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 364.0
HKD1_k127_4218944_6 Histidine phosphotransferase C-terminal domain K13588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 327.0
HKD1_k127_4218944_7 Iron permease FTR1 K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 330.0
HKD1_k127_4218944_8 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 321.0
HKD1_k127_4218944_9 Protein of unknown function (DUF1134) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 301.0
HKD1_k127_4264558_0 FAD linked oxidases, C-terminal domain K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 2.523e-225 707.0
HKD1_k127_4264558_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.081e-216 683.0
HKD1_k127_4264558_10 PTS IIA-like nitrogen-regulatory protein PtsN K02806 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 - 0.000000000000000000000000000000000000000000000000000002033 196.0
HKD1_k127_4264558_11 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000001719 155.0
HKD1_k127_4264558_2 Cysteine-rich domain K11473 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - 1.335e-203 642.0
HKD1_k127_4264558_3 FAD linked oxidase K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 533.0
HKD1_k127_4264558_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 466.0
HKD1_k127_4264558_5 Lipopolysaccharide-assembly, LptC-related K09774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 472.0
HKD1_k127_4264558_6 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 429.0
HKD1_k127_4264558_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 364.0
HKD1_k127_4264558_8 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 329.0
HKD1_k127_4264558_9 glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 317.0
HKD1_k127_4270125_0 ABC transporter K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 1.531e-294 916.0
HKD1_k127_4270125_1 Sulfide dehydrogenase K17218,K17229 - 1.8.2.3,1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 517.0
HKD1_k127_4270125_2 - - - - 0.00000000000000000000000000000000000000000000000000000001878 207.0
HKD1_k127_4270125_3 oxidation protein (SoxZ) K17227 - - 0.00000000000000000000000000000000004953 140.0
HKD1_k127_4270125_4 sulfur oxidation protein (SoxY) K17226 - - 0.0000000000000000000000000000148 123.0
HKD1_k127_4277034_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 2.075e-307 955.0
HKD1_k127_4277034_1 Ethanolamine ammonia lyase large subunit (EutB) K03735 - 4.3.1.7 3.755e-235 734.0
HKD1_k127_4277034_10 FeS assembly SUF system protein - - - 0.000000000000000000000000000000000000000000000001541 177.0
HKD1_k127_4277034_11 Belongs to the EutC family K03736 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0009350,GO:0019842,GO:0031419,GO:0032991,GO:0036094,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0097159,GO:1901363,GO:1902494 4.3.1.7 0.00000000000000000000000000000000000000001991 159.0
HKD1_k127_4277034_12 TfoX N-terminal domain K07343 - - 0.000000000000000000000000007609 119.0
HKD1_k127_4277034_2 Belongs to the DEAD box helicase family K03732,K11927 - 3.6.4.13 5.05e-224 704.0
HKD1_k127_4277034_3 Beta-eliminating lyase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 562.0
HKD1_k127_4277034_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 538.0
HKD1_k127_4277034_5 unsaturated fatty acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 524.0
HKD1_k127_4277034_6 FeS assembly protein SufD K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 371.0
HKD1_k127_4277034_7 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000414 249.0
HKD1_k127_4277034_8 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000004144 181.0
HKD1_k127_4277034_9 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000007459 183.0
HKD1_k127_4282057_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 534.0
HKD1_k127_4282057_1 Belongs to the protein N5-glutamine methyltransferase family K07320 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 436.0
HKD1_k127_4282057_2 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 417.0
HKD1_k127_4299917_0 DNA polymerase K02337 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1603.0
HKD1_k127_4299917_1 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 5.922e-307 953.0
HKD1_k127_4299917_10 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003938 261.0
HKD1_k127_4299917_11 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000001325 246.0
HKD1_k127_4299917_12 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000004073 261.0
HKD1_k127_4299917_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000004114 167.0
HKD1_k127_4299917_14 Protein of unknown function (DUF1467) - - - 0.000000000000000007083 88.0
HKD1_k127_4299917_15 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 0.0000000000415 64.0
HKD1_k127_4299917_16 Protein conserved in bacteria - - - 0.000000002293 63.0
HKD1_k127_4299917_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 9.622e-296 916.0
HKD1_k127_4299917_3 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 8.18e-253 791.0
HKD1_k127_4299917_4 NADH-quinone oxidoreductase chain K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 6.007e-235 743.0
HKD1_k127_4299917_5 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 5.668e-198 624.0
HKD1_k127_4299917_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 568.0
HKD1_k127_4299917_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 561.0
HKD1_k127_4299917_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 306.0
HKD1_k127_4299917_9 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 312.0
HKD1_k127_4368609_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 601.0
HKD1_k127_4368609_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 585.0
HKD1_k127_4368609_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 494.0
HKD1_k127_4368609_3 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 466.0
HKD1_k127_4368609_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 388.0
HKD1_k127_4368609_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 362.0
HKD1_k127_4368609_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 362.0
HKD1_k127_4368609_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 289.0
HKD1_k127_4368609_8 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000005713 253.0
HKD1_k127_4368609_9 Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000007913 76.0
HKD1_k127_4424132_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 528.0
HKD1_k127_4424132_1 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 305.0
HKD1_k127_4424132_2 AAA-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 289.0
HKD1_k127_4424132_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004453 278.0
HKD1_k127_4424132_5 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.0000001514 57.0
HKD1_k127_4436609_0 AAA-like domain - - - 0.0 1432.0
HKD1_k127_4436609_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365,K05366 - 2.4.1.129,3.4.16.4 0.0 1097.0
HKD1_k127_4436609_2 Alpha-2-Macroglobulin K06894 - - 1.757e-269 846.0
HKD1_k127_4436609_3 - - - - 6.715e-223 721.0
HKD1_k127_446683_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1104.0
HKD1_k127_446683_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 498.0
HKD1_k127_446683_11 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000000000000000000000000000003446 136.0
HKD1_k127_446683_12 - - - - 0.00000000000000000001332 94.0
HKD1_k127_446683_13 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000007464 88.0
HKD1_k127_446683_14 Zinc-dependent metalloprotease - - - 0.0000000000000000008274 89.0
HKD1_k127_446683_2 AFG1-like ATPase K06916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 456.0
HKD1_k127_446683_3 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 402.0
HKD1_k127_446683_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 313.0
HKD1_k127_446683_5 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 305.0
HKD1_k127_446683_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001338 264.0
HKD1_k127_446683_8 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005879 266.0
HKD1_k127_446683_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000005809 213.0
HKD1_k127_448156_0 cytochrome P450 - - - 2.664e-232 724.0
HKD1_k127_448156_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 429.0
HKD1_k127_448156_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 309.0
HKD1_k127_448156_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001439 280.0
HKD1_k127_448156_4 outer membrane porin, OprD family - - - 0.00000000000000000000000000000000000000000000000000000000000000002131 240.0
HKD1_k127_448156_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000001312 139.0
HKD1_k127_4499604_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 4.249e-273 861.0
HKD1_k127_4499604_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 8.092e-273 845.0
HKD1_k127_4499604_10 Cytochrome c - - - 0.000000000000000000000000008377 113.0
HKD1_k127_4499604_11 Dodecin K09165 - - 0.0000000000000000000001089 99.0
HKD1_k127_4499604_12 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000004521 100.0
HKD1_k127_4499604_13 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.000000536 60.0
HKD1_k127_4499604_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 328.0
HKD1_k127_4499604_3 cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003001 260.0
HKD1_k127_4499604_4 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003027 278.0
HKD1_k127_4499604_5 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007793 250.0
HKD1_k127_4499604_6 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000003423 229.0
HKD1_k127_4499604_7 Chorismate mutase, type II K04782 - 4.2.99.21 0.000000000000000000000000000000000000005589 149.0
HKD1_k127_4499604_9 Polymer-forming cytoskeletal - - - 0.000000000000000000000000005579 116.0
HKD1_k127_4518890_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 484.0
HKD1_k127_4518890_1 Pyrimidine 5'-nucleotidase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 352.0
HKD1_k127_4518890_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000006119 194.0
HKD1_k127_4518890_3 Anti-sigma-K factor rskA - - - 0.000000000000000000000000000000000000000000000258 175.0
HKD1_k127_4518890_4 Clp amino terminal domain, pathogenicity island component - - - 0.0000001186 53.0
HKD1_k127_4530111_0 Protein of unknown function (DUF459) K09795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 322.0
HKD1_k127_4530111_1 AsmA-like C-terminal region K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 301.0
HKD1_k127_4530111_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000000002497 229.0
HKD1_k127_4584138_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1159.0
HKD1_k127_4584138_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 377.0
HKD1_k127_4584138_2 periplasmic solute binding protein K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 356.0
HKD1_k127_4584138_3 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 304.0
HKD1_k127_4584138_4 Protein of unknown function (DUF1007) - - - 0.00000000000000000000000000000000000000000000000000000000000000000276 235.0
HKD1_k127_4584138_5 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000000000000000000000000000002569 143.0
HKD1_k127_4584138_6 COG2143 Thioredoxin-related protein K04084 - 1.8.1.8 0.0000000000000000000008498 99.0
HKD1_k127_4584138_7 SOS response K14160 - - 0.000000000000006312 87.0
HKD1_k127_4585636_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 2.199e-206 655.0
HKD1_k127_4585636_1 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 285.0
HKD1_k127_4585636_2 cyclic nucleotide binding K01420 - - 0.000000000000000000000000000000000000000000000000000144 193.0
HKD1_k127_4585636_3 PRC-barrel domain - - - 0.000000000000000000005532 105.0
HKD1_k127_4585636_4 - - - - 0.000000003827 60.0
HKD1_k127_4606242_0 Glucose / Sorbosone dehydrogenase - - - 1.332e-283 880.0
HKD1_k127_4606242_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000002101 55.0
HKD1_k127_4636540_0 serine threonine protein kinase K08282 - 2.7.11.1 8.017e-284 896.0
HKD1_k127_4636540_1 oxidase subunit I K00425 - 1.10.3.14 3.965e-241 752.0
HKD1_k127_4636540_10 YGGT family K02221 - - 0.0000000000000000000000000000009457 127.0
HKD1_k127_4636540_11 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000001173 113.0
HKD1_k127_4636540_12 23S rRNA-intervening sequence protein - - - 0.000000000000000000000002069 107.0
HKD1_k127_4636540_2 oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 492.0
HKD1_k127_4636540_3 Mg chelatase subunit ChlI K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 474.0
HKD1_k127_4636540_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 430.0
HKD1_k127_4636540_5 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 340.0
HKD1_k127_4636540_6 COG1716 FOG FHA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009649 271.0
HKD1_k127_4636540_7 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003633 261.0
HKD1_k127_4636540_8 COG1525 Micrococcal nuclease (thermonuclease) homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004647 260.0
HKD1_k127_4636540_9 Inner membrane component of T3SS, cytoplasmic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000005091 155.0
HKD1_k127_4661504_0 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 612.0
HKD1_k127_4661504_1 receptor K02014 - - 0.000000000000000000000000000000000000000000000000001781 185.0
HKD1_k127_4703075_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 601.0
HKD1_k127_4703075_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 571.0
HKD1_k127_4703075_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 426.0
HKD1_k127_4703075_3 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 333.0
HKD1_k127_4703075_4 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 306.0
HKD1_k127_4703075_5 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000006036 246.0
HKD1_k127_4703075_6 - - - - 0.000000000001037 70.0
HKD1_k127_473790_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 609.0
HKD1_k127_473790_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 479.0
HKD1_k127_473790_10 DNA integration - - - 0.000002231 52.0
HKD1_k127_473790_2 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 419.0
HKD1_k127_473790_3 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 359.0
HKD1_k127_473790_4 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008368 280.0
HKD1_k127_473790_5 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000000000000000000000000000009668 244.0
HKD1_k127_473790_6 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000001477 235.0
HKD1_k127_473790_7 Transcriptional regulator - - - 0.000000000000000000000000000000000006651 139.0
HKD1_k127_473790_8 - - - - 0.000000000000000000000000000000009319 131.0
HKD1_k127_480860_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1469.0
HKD1_k127_480860_1 PRC-barrel domain - - - 0.000006201 51.0
HKD1_k127_4821029_0 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 501.0
HKD1_k127_4821029_1 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 401.0
HKD1_k127_4821029_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 322.0
HKD1_k127_4821029_3 GMC oxidoreductase K03333 - 1.1.3.6 0.0000000000000000000000000000000000000000000000001378 185.0
HKD1_k127_485132_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 607.0
HKD1_k127_485132_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 381.0
HKD1_k127_485132_2 Dehydrogenase E1 component K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000001068 215.0
HKD1_k127_48979_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 465.0
HKD1_k127_48979_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 472.0
HKD1_k127_48979_2 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 372.0
HKD1_k127_48979_3 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 358.0
HKD1_k127_48979_4 Dienelactone hydrolase family K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001218 266.0
HKD1_k127_48979_5 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000923 243.0
HKD1_k127_48979_6 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000002767 230.0
HKD1_k127_5028346_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1172.0
HKD1_k127_5028346_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 3.509e-236 740.0
HKD1_k127_5028346_10 AraC-binding-like domain - - - 0.0000000000000000000000000000000000000000000005093 176.0
HKD1_k127_5028346_11 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000003328 103.0
HKD1_k127_5028346_12 Belongs to the ompA family K03286 - - 0.000000000000001355 91.0
HKD1_k127_5028346_13 Heat shock protein DnaJ domain protein K05516 - - 0.000000000003039 79.0
HKD1_k127_5028346_2 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 579.0
HKD1_k127_5028346_3 AI-2E family transporter K03548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 449.0
HKD1_k127_5028346_4 DnaJ C terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 406.0
HKD1_k127_5028346_5 Uncharacterized protein conserved in bacteria (DUF2066) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 342.0
HKD1_k127_5028346_6 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 296.0
HKD1_k127_5028346_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000235 274.0
HKD1_k127_5028346_8 Belongs to the DnaA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006428 264.0
HKD1_k127_5028346_9 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000000001187 218.0
HKD1_k127_5042821_0 transporter - - - 6.26e-235 736.0
HKD1_k127_5042821_1 MaoC like domain K14449 GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 582.0
HKD1_k127_5042821_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 494.0
HKD1_k127_5042821_3 Belongs to the HpcH HpaI aldolase family K01644,K14451 - 3.1.2.30,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 456.0
HKD1_k127_5042821_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 366.0
HKD1_k127_5042821_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 355.0
HKD1_k127_5042821_6 Periplasmic protein thiol disulfide oxidoreductase K02199 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007265 266.0
HKD1_k127_5042821_7 Phosphomethylpyrimidine kinase K00868 - 2.7.1.35 0.0000000000000000000000000000000000000000000000000000000000000002565 231.0
HKD1_k127_5042821_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000008566 81.0
HKD1_k127_5042821_9 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000000001094 68.0
HKD1_k127_5051034_1 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 299.0
HKD1_k127_5051034_2 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 257.0
HKD1_k127_5051034_3 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000003825 217.0
HKD1_k127_5051034_5 Protein of unknown function (DUF4239) - - - 0.00000000000005891 75.0
HKD1_k127_5052008_0 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 321.0
HKD1_k127_5052008_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000003815 79.0
HKD1_k127_5082970_0 UTP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000403 211.0
HKD1_k127_5082970_1 LTXXQ motif family protein - - - 0.0000000000000000000000000000000000000000000000002125 194.0
HKD1_k127_5082970_2 Periplasmic binding protein K02016 - - 0.000000000000000000000000000003537 122.0
HKD1_k127_5082970_3 PFAM acyl-CoA dehydrogenase K14448 - 1.3.8.12 0.00000000000000005157 80.0
HKD1_k127_5110444_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 587.0
HKD1_k127_5110444_1 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 481.0
HKD1_k127_5110444_2 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 353.0
HKD1_k127_5110444_3 helicase superfamily c-terminal domain K17675 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 299.0
HKD1_k127_5110444_5 Staphylococcal nuclease homologue - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002837 263.0
HKD1_k127_5110444_6 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000000000001965 221.0
HKD1_k127_5110444_7 S4 domain K04762 - - 0.0000000000000000000000000000001526 135.0
HKD1_k127_5110444_8 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000001501 65.0
HKD1_k127_5116270_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1232.0
HKD1_k127_5116270_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.414e-265 823.0
HKD1_k127_5116270_2 AsmA family K07289 - - 1.808e-259 850.0
HKD1_k127_5116270_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000001415 243.0
HKD1_k127_5116270_4 Ribbon-helix-helix domain - - - 0.000000000000000000002475 95.0
HKD1_k127_5126782_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1092.0
HKD1_k127_5126782_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 6.946e-224 700.0
HKD1_k127_5126782_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 585.0
HKD1_k127_5126782_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000000000001079 243.0
HKD1_k127_5148329_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 4.86e-252 788.0
HKD1_k127_5148329_1 GfdT protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 514.0
HKD1_k127_5148329_10 Glycosyl transferase family 2 - - - 0.0000000000000004903 80.0
HKD1_k127_5148329_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 491.0
HKD1_k127_5148329_3 TIGRFAM drug resistance transporter, Bcr CflA subfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 448.0
HKD1_k127_5148329_4 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 371.0
HKD1_k127_5148329_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003196 279.0
HKD1_k127_5148329_6 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001167 295.0
HKD1_k127_5148329_7 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002564 248.0
HKD1_k127_5148329_8 arsenate reductase K00537 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000001711 224.0
HKD1_k127_5151863_0 Histidine kinase K13587 - 2.7.13.3 4.379e-259 824.0
HKD1_k127_5151863_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 8.705e-200 627.0
HKD1_k127_5151863_2 Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 296.0
HKD1_k127_5151863_3 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006396 268.0
HKD1_k127_5151863_4 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001504 250.0
HKD1_k127_5151863_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000000000000000004488 171.0
HKD1_k127_5151863_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000744 136.0
HKD1_k127_5151863_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000003744 143.0
HKD1_k127_5151863_8 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000005598 106.0
HKD1_k127_5151863_9 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000002471 91.0
HKD1_k127_5167058_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1708.0
HKD1_k127_5167058_1 Circularly permuted ATP-grasp type 2 - - - 1e-323 1011.0
HKD1_k127_5167058_2 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 1.023e-273 859.0
HKD1_k127_5167058_3 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 424.0
HKD1_k127_5167058_4 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 344.0
HKD1_k127_5167058_5 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000192 227.0
HKD1_k127_5167058_6 Methylpurine-DNA glycosylase (MPG) K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000001114 222.0
HKD1_k127_5167058_7 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000001201 119.0
HKD1_k127_5167058_8 PQ loop repeat K15383 - - 0.00000000008849 63.0
HKD1_k127_5167058_9 PQ loop repeat K15383 - - 0.0001267 49.0
HKD1_k127_5168278_0 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000001463 203.0
HKD1_k127_5168278_1 Response regulator receiver - - - 0.00000000000000001098 90.0
HKD1_k127_5176579_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.292e-227 710.0
HKD1_k127_5176579_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 578.0
HKD1_k127_5176579_2 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 373.0
HKD1_k127_5176579_3 imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 363.0
HKD1_k127_5176579_4 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 349.0
HKD1_k127_5176579_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 310.0
HKD1_k127_5176579_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001052 274.0
HKD1_k127_5176579_7 Small multidrug resistance protein K11741 - - 0.000000000000000000000001663 106.0
HKD1_k127_5176579_8 Protein of unknown function (DUF2628) - - - 0.00000000000000000000009994 106.0
HKD1_k127_5181_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 3.092e-278 865.0
HKD1_k127_5181_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 1.187e-225 708.0
HKD1_k127_5181_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 622.0
HKD1_k127_5181_3 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 460.0
HKD1_k127_5181_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 341.0
HKD1_k127_5181_5 KR domain K00038 - 1.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 332.0
HKD1_k127_5181_6 - - - - 0.0000000004093 63.0
HKD1_k127_5184455_0 GMC oxidoreductase - - - 8.527e-248 776.0
HKD1_k127_5184455_1 Catalyzes the NAD( )-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non- methylotrophic organisms K00122 - 1.17.1.9 8.066e-221 692.0
HKD1_k127_5184455_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 339.0
HKD1_k127_5184455_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 306.0
HKD1_k127_5185578_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 1.158e-315 977.0
HKD1_k127_5185578_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 291.0
HKD1_k127_5185578_2 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000005166 216.0
HKD1_k127_5193619_0 Heat shock 70 kDa protein K04043 - - 0.0 1095.0
HKD1_k127_5193619_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 540.0
HKD1_k127_5193619_10 bleomycin resistance protein - - - 0.000000000000000000000000000000000000000000000000002351 190.0
HKD1_k127_5193619_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 531.0
HKD1_k127_5193619_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 436.0
HKD1_k127_5193619_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 320.0
HKD1_k127_5193619_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 312.0
HKD1_k127_5193619_6 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 317.0
HKD1_k127_5193619_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002102 248.0
HKD1_k127_5193619_8 Domain of unknown function (DUF1772) - - - 0.00000000000000000000000000000000000000000000000000000000004062 210.0
HKD1_k127_5193619_9 Disulfide bond formation protein DsbB K03611 - - 0.0000000000000000000000000000000000000000000000000000002937 198.0
HKD1_k127_5223387_0 Tricorn protease homolog K08676 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 444.0
HKD1_k127_5223387_1 Protein of unknown function (DUF1211) - - - 0.00000000000000002039 87.0
HKD1_k127_522364_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 334.0
HKD1_k127_522364_1 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 304.0
HKD1_k127_522364_2 Belongs to the RNase T2 family K01166,K01169 - 3.1.27.1,3.1.27.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000004272 280.0
HKD1_k127_522364_3 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000003944 200.0
HKD1_k127_5227505_0 5-aminolevulinic acid synthase K00643 - 2.3.1.37 3.998e-203 638.0
HKD1_k127_5227505_1 ErfK YbiS YcfS YnhG family protein K21470,K21572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 513.0
HKD1_k127_5227505_2 Enoyl-CoA hydratase/isomerase K01692,K05605 - 3.1.2.4,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 441.0
HKD1_k127_5227505_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 291.0
HKD1_k127_5227505_4 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 282.0
HKD1_k127_5230702_0 CoA binding domain K09181 - - 0.0 1178.0
HKD1_k127_5230702_1 Poly-beta-hydroxybutyrate polymerase N terminal K03821 - - 3.565e-240 758.0
HKD1_k127_5230702_10 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 311.0
HKD1_k127_5230702_11 Transcriptional regulator, Crp Fnr family K01420,K15861 - - 0.0000000000000000000000000000000000000000000000000004755 194.0
HKD1_k127_5230702_12 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000005161 176.0
HKD1_k127_5230702_13 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000003086 175.0
HKD1_k127_5230702_14 - - - - 0.000000000000000000000000000000000000000000009763 172.0
HKD1_k127_5230702_15 Universal stress protein - - - 0.00000000000000000000000000000000000000001637 164.0
HKD1_k127_5230702_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000007271 156.0
HKD1_k127_5230702_17 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0000000000000000000000000000000000000001423 156.0
HKD1_k127_5230702_18 Protein required for attachment to host cells - - - 0.000000000000000000000000000000000000003688 151.0
HKD1_k127_5230702_19 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000001732 123.0
HKD1_k127_5230702_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 612.0
HKD1_k127_5230702_20 - - - - 0.00000000000000000000000005355 109.0
HKD1_k127_5230702_21 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000002139 93.0
HKD1_k127_5230702_3 Zeta toxin K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 513.0
HKD1_k127_5230702_4 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 447.0
HKD1_k127_5230702_5 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 438.0
HKD1_k127_5230702_6 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 417.0
HKD1_k127_5230702_7 ABC-type transport auxiliary lipoprotein component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 376.0
HKD1_k127_5230702_8 ATPases associated with a variety of cellular activities K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 366.0
HKD1_k127_5230702_9 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 348.0
HKD1_k127_5246585_0 Flavin containing amine oxidoreductase - - - 2.135e-244 766.0
HKD1_k127_5246585_1 Cyclic nucleotide-monophosphate binding domain K07001 - - 0.0000000000000000000000000000000000000000000000001616 179.0
HKD1_k127_5246585_2 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000000000000000000000000002299 171.0
HKD1_k127_5246585_3 Small Multidrug Resistance protein K03297 - - 0.00000000000000000000000000000000003884 139.0
HKD1_k127_5247097_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1039.0
HKD1_k127_5247097_1 Staphylococcal nuclease homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000063 276.0
HKD1_k127_5247097_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000000000005108 160.0
HKD1_k127_5247097_3 Peptidase M15 K02395 - - 0.000000000000000000000000000000006695 138.0
HKD1_k127_5247097_4 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000001618 134.0
HKD1_k127_5247097_5 ggdef domain - - - 0.0000000000000000000000000004905 130.0
HKD1_k127_5247097_7 Methyltransferase domain - - - 0.00001857 47.0
HKD1_k127_5270057_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.0 1191.0
HKD1_k127_5270057_1 Cytochrome c-type biogenesis protein K02198 - - 0.0 1014.0
HKD1_k127_5270057_10 Glycine zipper 2TM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003378 228.0
HKD1_k127_5270057_11 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000002768 219.0
HKD1_k127_5270057_12 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000008434 159.0
HKD1_k127_5270057_13 Glycosyl hydrolase 108 - - - 0.000000000000000000000008439 103.0
HKD1_k127_5270057_14 Protein of unknown function (DUF1428) - - - 0.000000000000000000001069 97.0
HKD1_k127_5270057_15 Protein of unknown function (DUF1428) - - - 0.0000000000006109 78.0
HKD1_k127_5270057_16 Heavy-metal resistance - - - 0.000000000004938 72.0
HKD1_k127_5270057_17 - - - - 0.00000000007246 70.0
HKD1_k127_5270057_2 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 593.0
HKD1_k127_5270057_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 539.0
HKD1_k127_5270057_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 505.0
HKD1_k127_5270057_5 Two component transcriptional regulator K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 409.0
HKD1_k127_5270057_6 Transcriptional regulator K02483 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 405.0
HKD1_k127_5270057_7 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 318.0
HKD1_k127_5270057_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000003636 237.0
HKD1_k127_5274776_0 Protein of unknown function DUF262 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 506.0
HKD1_k127_5274776_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 476.0
HKD1_k127_5274776_2 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 422.0
HKD1_k127_5274776_3 Protein of unknown function (DUF952) - - - 0.000000000000000000000000000000132 128.0
HKD1_k127_5274776_4 - - - - 0.0000000000000009582 79.0
HKD1_k127_5278237_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1000.0
HKD1_k127_5278237_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 9.799e-243 758.0
HKD1_k127_5278237_10 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000003727 118.0
HKD1_k127_5278237_11 Transglycosylase associated protein - - - 0.000000000000000002234 89.0
HKD1_k127_5278237_2 SurA N-terminal domain K01802,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 543.0
HKD1_k127_5278237_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 449.0
HKD1_k127_5278237_4 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 395.0
HKD1_k127_5278237_5 Anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 364.0
HKD1_k127_5278237_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 332.0
HKD1_k127_5278237_7 Nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000003301 170.0
HKD1_k127_5278237_8 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000000000000003057 169.0
HKD1_k127_5278237_9 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000001219 140.0
HKD1_k127_5279845_0 penicillin-binding protein K05367 - 2.4.1.129 1.72e-289 908.0
HKD1_k127_5279845_1 depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 468.0
HKD1_k127_5279845_2 Lipid A oxidase K12980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001735 288.0
HKD1_k127_5279845_3 Domain of unknown function (DUF4175) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004955 248.0
HKD1_k127_5279845_4 Alpha-2-Macroglobulin K06894 - - 0.00000000000000000000000000000000006324 136.0
HKD1_k127_5305482_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5,6.2.1.9 4.031e-194 611.0
HKD1_k127_5305482_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 574.0
HKD1_k127_5305482_2 E1 component K00164 - 1.2.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 555.0
HKD1_k127_5305482_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 499.0
HKD1_k127_5305482_4 Zinc-dependent metalloprotease - - - 0.000000000000000000000000000000000000000000000000000000001376 209.0
HKD1_k127_5312590_0 AcrB/AcrD/AcrF family - - - 0.0 1328.0
HKD1_k127_5312590_1 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 596.0
HKD1_k127_5312590_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 291.0
HKD1_k127_534501_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 2.485e-210 659.0
HKD1_k127_534501_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 1.718e-209 657.0
HKD1_k127_534501_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 299.0
HKD1_k127_534501_11 ABC 3 transport family K09816 GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 295.0
HKD1_k127_534501_12 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000005006 266.0
HKD1_k127_534501_13 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000000000000000002499 215.0
HKD1_k127_534501_14 Outer membrane protein beta-barrel domain K16079 - - 0.000000000000000000000000000000000000000000000000000003064 200.0
HKD1_k127_534501_15 Cupin superfamily (DUF985) K09705 - - 0.00000000000000000000000000000000000000000000000000001703 198.0
HKD1_k127_534501_16 EF hand - - - 0.000000000000000000000000000000000000000000000000005247 184.0
HKD1_k127_534501_17 - - - - 0.000000000000000000000000000000000000001721 151.0
HKD1_k127_534501_19 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000006812 107.0
HKD1_k127_534501_2 NYN domain - - - 2.546e-203 648.0
HKD1_k127_534501_3 Belongs to the thiolase family K00626 - 2.3.1.9 5.326e-195 614.0
HKD1_k127_534501_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 531.0
HKD1_k127_534501_5 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 493.0
HKD1_k127_534501_6 KR domain K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 404.0
HKD1_k127_534501_7 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 345.0
HKD1_k127_534501_8 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 336.0
HKD1_k127_534501_9 synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 299.0
HKD1_k127_5349550_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.517e-272 846.0
HKD1_k127_5349550_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 2.154e-271 842.0
HKD1_k127_5349550_10 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000001827 180.0
HKD1_k127_5349550_11 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000001282 115.0
HKD1_k127_5349550_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 8.277e-219 686.0
HKD1_k127_5349550_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 419.0
HKD1_k127_5349550_4 TatD family K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 414.0
HKD1_k127_5349550_5 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 421.0
HKD1_k127_5349550_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 400.0
HKD1_k127_5349550_7 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 377.0
HKD1_k127_5349550_8 Short-chain dehydrogenase reductase SDR - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 353.0
HKD1_k127_5349550_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000005666 226.0
HKD1_k127_5349588_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788,K07789 - - 0.0 1093.0
HKD1_k127_5349588_1 Permease family K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 503.0
HKD1_k127_5349588_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799,K18990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 439.0
HKD1_k127_5349588_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000001559 79.0
HKD1_k127_5397119_0 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 6.735e-206 661.0
HKD1_k127_5397119_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 542.0
HKD1_k127_5397119_10 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 357.0
HKD1_k127_5397119_11 response regulator K15012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 337.0
HKD1_k127_5397119_12 Two component transcriptional regulator PhoB, winged helix family K07657 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 317.0
HKD1_k127_5397119_13 Domain of unknown function (DUF1993) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 300.0
HKD1_k127_5397119_14 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 290.0
HKD1_k127_5397119_15 Protein tyrosine serine phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006479 282.0
HKD1_k127_5397119_16 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001599 263.0
HKD1_k127_5397119_17 protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000009982 218.0
HKD1_k127_5397119_18 Belongs to the TPP enzyme family K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000000007594 212.0
HKD1_k127_5397119_2 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 507.0
HKD1_k127_5397119_20 DNA repair protein MmcB-like - - - 0.0000000000000000000000000000000000000000000000000007538 192.0
HKD1_k127_5397119_21 Domain of unknown function (DUF4112) - - - 0.00000000000000000000000000000000000000000002547 167.0
HKD1_k127_5397119_22 alpha beta - - - 0.000000000000000000000000000002799 134.0
HKD1_k127_5397119_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 475.0
HKD1_k127_5397119_4 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 437.0
HKD1_k127_5397119_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 432.0
HKD1_k127_5397119_6 phosphate transport system permease K02038 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 419.0
HKD1_k127_5397119_7 Polyphosphate kinase 2 (PPK2) K22468 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0042802,GO:0044237 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 421.0
HKD1_k127_5397119_8 Belongs to the peptidase S16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 434.0
HKD1_k127_5397119_9 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 390.0
HKD1_k127_5431980_0 LexA-binding, inner membrane-associated putative hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 331.0
HKD1_k127_5431980_1 tetR family - - - 0.0000000000000000000000000000000000000000000000000000004136 199.0
HKD1_k127_5431980_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000007049 106.0
HKD1_k127_5431980_3 TadE-like protein - - - 0.00000000001454 68.0
HKD1_k127_5442144_0 - - - - 1.856e-259 817.0
HKD1_k127_5442144_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 4.781e-237 740.0
HKD1_k127_5442144_10 Squalene/phytoene synthase K02291,K18163 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000006852 135.0
HKD1_k127_5442144_12 Protein of unknown function (DUF3175) - - - 0.00000000000000000000000000226 121.0
HKD1_k127_5442144_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 553.0
HKD1_k127_5442144_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 435.0
HKD1_k127_5442144_4 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 427.0
HKD1_k127_5442144_5 Lysin motif K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 373.0
HKD1_k127_5442144_6 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 350.0
HKD1_k127_5442144_7 Preprotein translocase K03210 - - 0.0000000000000000000000000000000000000000007337 159.0
HKD1_k127_5442144_8 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000008897 140.0
HKD1_k127_5442144_9 GDYXXLXY protein - - - 0.00000000000000000000000000000000009488 151.0
HKD1_k127_5444727_0 nuclear chromosome segregation - - - 1.002e-253 803.0
HKD1_k127_5444727_1 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 370.0
HKD1_k127_5444727_2 mandelate racemase muconate lactonizing K19802 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 351.0
HKD1_k127_5463465_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.003e-208 667.0
HKD1_k127_5463465_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 506.0
HKD1_k127_5463465_2 secondary thiamine-phosphate synthase - - - 0.0000000000000000000000000000000000000000000000002169 183.0
HKD1_k127_5463465_3 Domain of unknown function (DUF4212) K14393 - - 0.00000000000000000000000000000000000000005144 152.0
HKD1_k127_5463465_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000002073 153.0
HKD1_k127_5492267_0 low-complexity proteins - - - 4.893e-231 734.0
HKD1_k127_5492267_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.000000000000000000000000000000000000000000000000000000000000000001656 228.0
HKD1_k127_5492267_2 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000004478 174.0
HKD1_k127_5499899_0 Signal transduction histidine kinase K07638 - 2.7.13.3 1.259e-224 706.0
HKD1_k127_5499899_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 521.0
HKD1_k127_5499899_2 Two component transcriptional regulator K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 360.0
HKD1_k127_5499899_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002454 228.0
HKD1_k127_5499899_4 transcriptional regulator - - - 0.00000000000000000000000000000000000000000002668 170.0
HKD1_k127_5499899_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.0000000000000000000000000000001348 125.0
HKD1_k127_5511536_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 525.0
HKD1_k127_5511536_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 383.0
HKD1_k127_5511536_2 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000000000000000001514 270.0
HKD1_k127_5511536_3 Tetratricopeptide repeat - - - 0.00000000000000000000000003195 120.0
HKD1_k127_5511536_4 PspC domain protein - - - 0.00000000000002105 76.0
HKD1_k127_5511536_5 Cytochrome c - - - 0.0000000000001185 82.0
HKD1_k127_55891_0 Belongs to the heme-copper respiratory oxidase family K00404 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 8.538e-306 944.0
HKD1_k127_55891_1 copper-translocating P-type ATPase K01533 - 3.6.3.4 5.234e-260 822.0
HKD1_k127_55891_10 Cytochrome oxidase maturation protein - - - 0.000000000000008873 79.0
HKD1_k127_55891_11 Cbb3-type cytochrome oxidase K00407 - - 0.0000000006291 61.0
HKD1_k127_55891_2 Cytochrome C oxidase accessory protein CcoG - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.892e-231 725.0
HKD1_k127_55891_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 442.0
HKD1_k127_55891_4 cytochrome C K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 402.0
HKD1_k127_55891_5 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007491 253.0
HKD1_k127_55891_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000959 162.0
HKD1_k127_55891_7 - - - - 0.000000000000000000000000000000000000009664 150.0
HKD1_k127_55891_8 FixH - - - 0.000000000000000000000000000000000001523 149.0
HKD1_k127_55891_9 - - - - 0.000000000000000000000000007697 114.0
HKD1_k127_5625672_0 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 473.0
HKD1_k127_5625672_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 343.0
HKD1_k127_5625672_2 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 329.0
HKD1_k127_5625672_3 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 304.0
HKD1_k127_5625672_5 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.00000000005508 62.0
HKD1_k127_5626719_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.0 1117.0
HKD1_k127_5626719_1 reductase K00001,K14446 - 1.1.1.1,1.3.1.85 5.998e-261 809.0
HKD1_k127_5626719_2 Ribonuclease, BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 354.0
HKD1_k127_5626719_4 - - - - 0.000000000000000000001004 98.0
HKD1_k127_5654703_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 369.0
HKD1_k127_5654703_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 319.0
HKD1_k127_5654703_2 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 318.0
HKD1_k127_5654703_3 GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002781 242.0
HKD1_k127_5654703_4 Phasin protein - - - 0.0000000000000000000000000000000000000000000141 167.0
HKD1_k127_5656323_0 Nitrite reductase NAD(P)H , large subunit K00362 - 1.7.1.15 0.0 1482.0
HKD1_k127_5656323_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1289.0
HKD1_k127_5656323_10 - - - - 0.0000000000000002178 92.0
HKD1_k127_5656323_11 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000001519 71.0
HKD1_k127_5656323_2 Major Facilitator Superfamily K02575 - - 1.047e-209 661.0
HKD1_k127_5656323_3 NMT1-like family K15576,K22067 - - 7.921e-204 640.0
HKD1_k127_5656323_4 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 511.0
HKD1_k127_5656323_5 ANTAR K07183 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 283.0
HKD1_k127_5656323_6 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000007682 259.0
HKD1_k127_5656323_7 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000000000000000000000000000000000000000000000000000001556 213.0
HKD1_k127_5656323_8 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000361 199.0
HKD1_k127_5656323_9 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000000000000000000000000000000000000000000000001677 190.0
HKD1_k127_565850_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01738,K01740 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47,2.5.1.49 2.187e-240 748.0
HKD1_k127_565850_1 AMP-binding enzyme K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 583.0
HKD1_k127_565850_10 Cytochrome c - - - 0.0000000000000000000000000000000001673 138.0
HKD1_k127_565850_11 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000004279 117.0
HKD1_k127_565850_12 - - - - 0.000000000000000000000006149 109.0
HKD1_k127_565850_13 DJ-1/PfpI family K18199 - 4.2.1.103 0.00000000000000000000008262 104.0
HKD1_k127_565850_2 Prokaryotic glutathione synthetase, ATP-grasp domain K05844,K14940 - 6.3.2.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 461.0
HKD1_k127_565850_3 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 333.0
HKD1_k127_565850_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 317.0
HKD1_k127_565850_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 291.0
HKD1_k127_565850_6 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000001521 207.0
HKD1_k127_565850_7 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000000000000000002697 177.0
HKD1_k127_565850_8 intracellular protease amidase K18199 - 4.2.1.103 0.0000000000000000000000000000000000000000000002571 174.0
HKD1_k127_565850_9 helix_turn_helix, mercury resistance K13639 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000002274 155.0
HKD1_k127_5679842_0 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 589.0
HKD1_k127_5679842_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 451.0
HKD1_k127_5679842_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000001754 170.0
HKD1_k127_5679842_5 response regulator - - - 0.000001139 57.0
HKD1_k127_5679842_6 Golgi to endosome transport K07881 GO:0000166,GO:0000323,GO:0001775,GO:0001845,GO:0001882,GO:0001883,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005768,GO:0005769,GO:0005770,GO:0005773,GO:0005783,GO:0005791,GO:0005794,GO:0005795,GO:0005798,GO:0005802,GO:0005829,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006661,GO:0006793,GO:0006796,GO:0006810,GO:0006873,GO:0006885,GO:0006887,GO:0006892,GO:0006895,GO:0006897,GO:0006909,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007033,GO:0007040,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007264,GO:0007265,GO:0007589,GO:0008092,GO:0008104,GO:0008150,GO:0008152,GO:0008543,GO:0008610,GO:0008654,GO:0009058,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009987,GO:0010008,GO:0010033,GO:0012505,GO:0012506,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0016197,GO:0016324,GO:0016462,GO:0016482,GO:0016787,GO:0016817,GO:0016818,GO:0017022,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019637,GO:0019725,GO:0022607,GO:0023052,GO:0030003,GO:0030004,GO:0030100,GO:0030133,GO:0030135,GO:0030136,GO:0030139,GO:0030140,GO:0030141,GO:0030641,GO:0030659,GO:0030667,GO:0031090,GO:0031410,GO:0031489,GO:0031901,GO:0031982,GO:0031984,GO:0032456,GO:0032482,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032879,GO:0032880,GO:0032940,GO:0033036,GO:0035556,GO:0035639,GO:0036094,GO:0036230,GO:0036477,GO:0042119,GO:0042175,GO:0042221,GO:0042592,GO:0042599,GO:0042742,GO:0043025,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043277,GO:0043299,GO:0043312,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044297,GO:0044344,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045017,GO:0045055,GO:0045176,GO:0045177,GO:0045202,GO:0045321,GO:0045335,GO:0045851,GO:0045995,GO:0046474,GO:0046486,GO:0046488,GO:0046903,GO:0046907,GO:0048193,GO:0048471,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050878,GO:0050896,GO:0051049,GO:0051128,GO:0051179,GO:0051234,GO:0051239,GO:0051452,GO:0051453,GO:0051641,GO:0051649,GO:0051704,GO:0051707,GO:0051716,GO:0055037,GO:0055038,GO:0055067,GO:0055080,GO:0055082,GO:0060627,GO:0065007,GO:0065008,GO:0070820,GO:0070821,GO:0070848,GO:0070887,GO:0070925,GO:0071310,GO:0071363,GO:0071495,GO:0071704,GO:0071774,GO:0071840,GO:0071944,GO:0080171,GO:0090382,GO:0090383,GO:0090386,GO:0090387,GO:0090390,GO:0090407,GO:0097159,GO:0097208,GO:0097367,GO:0097458,GO:0097708,GO:0098542,GO:0098588,GO:0098590,GO:0098657,GO:0098771,GO:0098791,GO:0098805,GO:0099503,GO:1901265,GO:1901363,GO:1901576,GO:2000026 - 0.000004554 52.0
HKD1_k127_5693289_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 9.98e-290 895.0
HKD1_k127_5693289_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335 - 1.6.5.3 3.141e-273 848.0
HKD1_k127_5693289_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 441.0
HKD1_k127_5693289_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00127 - - 0.000000000000000000000000000000000000000000000000000000000000001184 223.0
HKD1_k127_5693289_4 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000004357 213.0
HKD1_k127_5693289_5 Formate dehydrogenase subunit alpha K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000007517 181.0
HKD1_k127_5693289_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000001278 173.0
HKD1_k127_5693289_7 Aromatic acid exporter family member 1 - - - 0.0000000000000001188 92.0
HKD1_k127_5760121_0 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 424.0
HKD1_k127_5760121_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001475 246.0
HKD1_k127_5760121_2 nuclear export factor GLE1 K09796 - - 0.00000000000000000000000000000000000003076 148.0
HKD1_k127_581289_0 Proton-conducting membrane transporter K12141 - - 1.099e-243 759.0
HKD1_k127_581289_1 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 488.0
HKD1_k127_581289_2 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 332.0
HKD1_k127_581289_3 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000006131 209.0
HKD1_k127_581289_4 Proton-conducting membrane transporter - - - 0.00000000000000000000000000000000000000000000004701 171.0
HKD1_k127_5851878_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 3.208e-236 746.0
HKD1_k127_5851878_1 His Kinase A (phosphoacceptor) domain - - - 6.956e-196 624.0
HKD1_k127_5851878_2 pyridine nucleotide-disulfide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 584.0
HKD1_k127_5851878_3 Clp amino terminal domain, pathogenicity island component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 366.0
HKD1_k127_5851878_4 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000001 242.0
HKD1_k127_5851878_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000000002878 113.0
HKD1_k127_5851878_6 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000004047 73.0
HKD1_k127_5990241_0 ABC transporter K06158 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 581.0
HKD1_k127_5990241_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001956 274.0
HKD1_k127_5990241_2 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.00000000000000000000000000000000224 134.0
HKD1_k127_5990241_3 PFAM AIG2 family protein K20757 - 4.3.1.27 0.000000000003718 72.0
HKD1_k127_599059_0 Required for chromosome condensation and partitioning K03529 - - 7.897e-291 921.0
HKD1_k127_599059_1 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 1.961e-194 611.0
HKD1_k127_599059_2 flavoprotein involved in K transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 559.0
HKD1_k127_599059_3 endonuclease III K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 543.0
HKD1_k127_599059_4 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 299.0
HKD1_k127_599059_5 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 301.0
HKD1_k127_599059_6 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000000000001669 156.0
HKD1_k127_599059_7 - - - - 0.00000000000000000000002794 114.0
HKD1_k127_599059_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000004338 87.0
HKD1_k127_600642_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.832e-307 949.0
HKD1_k127_600642_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002675 255.0
HKD1_k127_600642_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000000000000000000000002326 184.0
HKD1_k127_600642_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.000000000000000000008789 98.0
HKD1_k127_600642_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000628 66.0
HKD1_k127_600642_5 Alginate export - - - 0.00001063 51.0
HKD1_k127_600642_6 OmpA-like transmembrane domain K16079 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0005378 48.0
HKD1_k127_6047735_0 Retinal pigment epithelial membrane protein - - - 6.159e-200 633.0
HKD1_k127_6047735_1 serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 398.0
HKD1_k127_6047735_2 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 350.0
HKD1_k127_6047735_3 Molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001412 280.0
HKD1_k127_6047735_4 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000102 237.0
HKD1_k127_6047735_5 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000006326 128.0
HKD1_k127_6056768_0 LuxR family transcriptional regulator K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 604.0
HKD1_k127_6056768_1 Belongs to the FPP GGPP synthase family K00795 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 329.0
HKD1_k127_6056768_2 Protein conserved in bacteria K09778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001753 254.0
HKD1_k127_6056768_3 Nad-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000003206 248.0
HKD1_k127_6056768_4 cyclic nucleotide binding K01420 - - 0.000000000000000000000000000000000000000000346 168.0
HKD1_k127_6062251_0 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 461.0
HKD1_k127_6062251_1 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 306.0
HKD1_k127_6062251_2 molybdopterin biosynthesis MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000009672 113.0
HKD1_k127_6066845_0 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 402.0
HKD1_k127_6066845_1 RNA polymerase sigma factor RpoH K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004744 264.0
HKD1_k127_6079436_0 His Kinase A (phospho-acceptor) domain K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 576.0
HKD1_k127_6079436_1 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 490.0
HKD1_k127_6079436_10 Transglycosylase associated protein - - - 0.0000000000000000000000002814 107.0
HKD1_k127_6079436_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 451.0
HKD1_k127_6079436_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 431.0
HKD1_k127_6079436_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 330.0
HKD1_k127_6079436_5 Sigma-54 interaction domain K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 287.0
HKD1_k127_6079436_6 MarR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002133 269.0
HKD1_k127_6079436_7 PFAM pentapeptide repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003786 263.0
HKD1_k127_6079436_8 oligoketide cyclase lipid transport protein K18588 - - 0.000000000000000000000000000000000000000000000000000104 190.0
HKD1_k127_6079436_9 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000008478 185.0
HKD1_k127_6083170_0 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.0 1236.0
HKD1_k127_6083170_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1e-323 996.0
HKD1_k127_6083170_10 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000004336 183.0
HKD1_k127_6083170_11 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000001262 167.0
HKD1_k127_6083170_12 Pfam:DUF1049 - - - 0.0000000000000000000000000000000000000003389 151.0
HKD1_k127_6083170_13 Protein of unknown function (FYDLN_acid) - - - 0.000000000000000000000000000000000000001659 152.0
HKD1_k127_6083170_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 4.712e-241 749.0
HKD1_k127_6083170_3 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 2.7e-206 649.0
HKD1_k127_6083170_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 2.389e-196 625.0
HKD1_k127_6083170_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 516.0
HKD1_k127_6083170_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 397.0
HKD1_k127_6083170_7 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 398.0
HKD1_k127_6083170_8 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008205 268.0
HKD1_k127_6083170_9 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000005077 242.0
HKD1_k127_6091730_0 Involved in the TonB-independent uptake of proteins K03641 - - 1.839e-227 712.0
HKD1_k127_6091730_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 316.0
HKD1_k127_6091730_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 295.0
HKD1_k127_6091730_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 302.0
HKD1_k127_6091730_4 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003183 241.0
HKD1_k127_6091730_5 TIGRFAM protein TolA K03646 - - 0.0000000000000000000000000000000000000000000000000000000000000000002325 236.0
HKD1_k127_6091730_6 chlorophyll binding K02067,K03286,K03640 - - 0.00000000000000000000000000000000001867 153.0
HKD1_k127_6093540_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.009e-234 732.0
HKD1_k127_6093540_1 lytic murein transglycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 507.0
HKD1_k127_6093540_10 Protein of unknown function (DUF4236) - - - 0.00000000000000000000000000000000000000001434 167.0
HKD1_k127_6093540_11 4Fe-4S double cluster binding domain K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000009486 111.0
HKD1_k127_6093540_2 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 477.0
HKD1_k127_6093540_3 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 431.0
HKD1_k127_6093540_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 351.0
HKD1_k127_6093540_5 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 346.0
HKD1_k127_6093540_6 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 346.0
HKD1_k127_6093540_7 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000001226 209.0
HKD1_k127_6093540_8 Membrane K03646 - - 0.00000000000000000000000000000000000000000000001077 193.0
HKD1_k127_6093540_9 cytokinin biosynthetic process - - - 0.000000000000000000000000000000000000000000008736 168.0
HKD1_k127_6144846_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1386.0
HKD1_k127_6144846_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 6.154e-257 795.0
HKD1_k127_6144846_10 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000001436 229.0
HKD1_k127_6144846_11 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000003115 199.0
HKD1_k127_6144846_12 Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone K03880 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000334 182.0
HKD1_k127_6144846_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000001706 167.0
HKD1_k127_6144846_14 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000002097 151.0
HKD1_k127_6144846_15 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000005125 129.0
HKD1_k127_6144846_16 Thioesterase K18700 - 3.1.2.29 0.0000000000000000002056 96.0
HKD1_k127_6144846_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 3.571e-236 734.0
HKD1_k127_6144846_20 Domain of unknown function (DUF1993) K09983 - - 0.0002916 46.0
HKD1_k127_6144846_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 563.0
HKD1_k127_6144846_4 Pyridoxal-phosphate dependent enzyme K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 513.0
HKD1_k127_6144846_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 462.0
HKD1_k127_6144846_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 390.0
HKD1_k127_6144846_7 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 368.0
HKD1_k127_6144846_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 347.0
HKD1_k127_6144846_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 321.0
HKD1_k127_6155609_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1150.0
HKD1_k127_6155609_1 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000483 222.0
HKD1_k127_6155609_5 SnoaL-like domain K06893 - - 0.000001509 59.0
HKD1_k127_6166474_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.281e-230 718.0
HKD1_k127_6166474_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 1.724e-199 632.0
HKD1_k127_6166474_10 Protein of unknown function (DUF2948) - - - 0.00000000000000000000000000000000000000000000000009948 184.0
HKD1_k127_6166474_11 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000001987 98.0
HKD1_k127_6166474_12 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000001651 79.0
HKD1_k127_6166474_13 Resolvase - - - 0.0000001815 53.0
HKD1_k127_6166474_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 559.0
HKD1_k127_6166474_3 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768,K01769 - 4.6.1.1,4.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 458.0
HKD1_k127_6166474_4 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 357.0
HKD1_k127_6166474_5 GDP-mannose 4,6 dehydratase K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 331.0
HKD1_k127_6166474_6 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 316.0
HKD1_k127_6166474_7 Belongs to the UPF0262 family - - - 0.000000000000000000000000000000000000000000000000000000000000004912 226.0
HKD1_k127_6166474_8 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000001619 218.0
HKD1_k127_6166474_9 Low molecular weight phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.00000000000000000000000000000000000000000000000000000005516 200.0
HKD1_k127_6175488_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1275.0
HKD1_k127_6175488_1 Amidohydrolase family K01465 - 3.5.2.3 6.761e-233 732.0
HKD1_k127_6175488_10 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 347.0
HKD1_k127_6175488_11 Peptidase dimerisation domain K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 325.0
HKD1_k127_6175488_12 Lysine exporter protein LysE YggA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 304.0
HKD1_k127_6175488_13 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 310.0
HKD1_k127_6175488_14 glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007479 279.0
HKD1_k127_6175488_15 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008951 267.0
HKD1_k127_6175488_16 Metal dependent phosphohydrolases with conserved 'HD' motif. K06952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002698 261.0
HKD1_k127_6175488_17 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000004329 227.0
HKD1_k127_6175488_18 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000003413 200.0
HKD1_k127_6175488_19 - - - - 0.000000000000000000000000000000000000000000000000000002258 198.0
HKD1_k127_6175488_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.152e-200 641.0
HKD1_k127_6175488_20 Protein of unknown function (DUF2385) - - - 0.0000000000000000000000000000000000000000000002192 170.0
HKD1_k127_6175488_21 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000000000000000001895 139.0
HKD1_k127_6175488_22 - - - - 0.0000000000000000000000005865 107.0
HKD1_k127_6175488_24 - - - - 0.0000000000000001911 79.0
HKD1_k127_6175488_25 Domain of unknown function (DUF1902) - - - 0.00004968 51.0
HKD1_k127_6175488_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 554.0
HKD1_k127_6175488_4 FAD linked oxidases, C-terminal domain K00102 GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0004458,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006089,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016053,GO:0016491,GO:0016614,GO:0016898,GO:0019249,GO:0019516,GO:0019752,GO:0022900,GO:0022904,GO:0030447,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046394,GO:0048037,GO:0050660,GO:0050662,GO:0051990,GO:0055114,GO:0071704,GO:0071949,GO:0072330,GO:0097159,GO:0099615,GO:1901265,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 554.0
HKD1_k127_6175488_5 belongs to the nudix hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 530.0
HKD1_k127_6175488_6 histone deacetylase K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 480.0
HKD1_k127_6175488_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 469.0
HKD1_k127_6175488_8 Short-chain dehydrogenase reductase SDR K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 426.0
HKD1_k127_6175488_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 382.0
HKD1_k127_6217942_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 5.088e-210 659.0
HKD1_k127_6217942_1 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 2.279e-203 641.0
HKD1_k127_6217942_2 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 568.0
HKD1_k127_6225424_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 0.0 1148.0
HKD1_k127_6225424_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 545.0
HKD1_k127_6225424_10 Bacterial dnaA protein helix-turn-helix domain - - - 0.00000000000000000000000000000000003274 139.0
HKD1_k127_6225424_11 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000004051 138.0
HKD1_k127_6225424_2 PFAM Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 424.0
HKD1_k127_6225424_3 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 330.0
HKD1_k127_6225424_4 Protein of unknown function (DUF1214) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001273 245.0
HKD1_k127_6225424_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000006472 234.0
HKD1_k127_6225424_6 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000000000000004832 210.0
HKD1_k127_6225424_7 Fe-S metabolism associated domain K02426 - - 0.000000000000000000000000000000000000000000000000002245 189.0
HKD1_k127_6225424_8 Protein of unknown function (DUF1491) - - - 0.0000000000000000000000000000000000000002471 152.0
HKD1_k127_6225424_9 integral membrane protein - - - 0.00000000000000000000000000000000000005816 157.0
HKD1_k127_623609_0 Diguanylate cyclase phosphodiesterase with PAS PAC K13245 - 3.1.4.52 0.0 1442.0
HKD1_k127_623609_1 Threonine synthase K01733 GO:0003674,GO:0003824,GO:0004795,GO:0006082,GO:0006520,GO:0006566,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016311,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 2.379e-209 660.0
HKD1_k127_623609_10 Protein of unknown function (DUF983) - - - 0.00000000000000000000000000000000000000003009 160.0
HKD1_k127_623609_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 3.218e-209 652.0
HKD1_k127_623609_3 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 527.0
HKD1_k127_623609_4 Cytochrome c oxidase subunit III K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008678 488.0
HKD1_k127_623609_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 447.0
HKD1_k127_623609_6 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 299.0
HKD1_k127_623609_7 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000000000000000006235 265.0
HKD1_k127_623609_8 SURF1 family K14998 GO:0006996,GO:0007005,GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0033108,GO:0033617,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000003725 245.0
HKD1_k127_623609_9 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.0000000000000000000000000000000000000000000000000000000000001042 218.0
HKD1_k127_6244178_0 NLP P60 protein - - - 8.132e-293 914.0
HKD1_k127_6244178_1 4 iron, 4 sulfur cluster binding. It is involved in the biological process described with RNA modification - - - 0.000000000000000000000000114 108.0
HKD1_k127_6267580_0 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 543.0
HKD1_k127_6267580_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 399.0
HKD1_k127_6267580_2 ferredoxin K04755 - - 0.00000000000000000000000000000000000000000000000001607 182.0
HKD1_k127_6267580_3 Histidine Phosphotransfer domain - - - 0.000000000000000000000001446 110.0
HKD1_k127_63123_0 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000002259 242.0
HKD1_k127_63123_1 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000008623 190.0
HKD1_k127_63123_2 AAA domain - - - 0.0000000000000000000000000000000000000004846 161.0
HKD1_k127_63123_3 Protein of unknown function - - - 0.000000000000000000000000000000006963 133.0
HKD1_k127_6415262_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 1.149e-234 730.0
HKD1_k127_6415262_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 528.0
HKD1_k127_6415262_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 489.0
HKD1_k127_6415262_3 PFAM ABC transporter K01995,K15783 GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 3.5.4.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 401.0
HKD1_k127_6415262_4 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 357.0
HKD1_k127_6415262_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000001322 208.0
HKD1_k127_6415262_6 - - - - 0.000000000000000000000001064 109.0
HKD1_k127_6415262_7 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000002217 114.0
HKD1_k127_6415262_8 Excalibur calcium-binding domain - - - 0.000000000000007223 80.0
HKD1_k127_6458859_0 Multi-copper - - - 4.997e-265 822.0
HKD1_k127_6458859_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 599.0
HKD1_k127_6458859_2 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000000000000000000001403 199.0
HKD1_k127_6458859_3 GYD domain - - - 0.0000000000000000000000000000000001198 135.0
HKD1_k127_6458859_4 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000005965 104.0
HKD1_k127_6458859_5 - - - - 0.000000000000000001724 91.0
HKD1_k127_6458859_7 Protein of unknown function (DUF1059) - - - 0.0000168 51.0
HKD1_k127_6535927_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.195e-242 754.0
HKD1_k127_6535927_1 MgsA AAA+ ATPase C terminal K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 4.497e-216 676.0
HKD1_k127_6535927_10 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 303.0
HKD1_k127_6535927_11 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 291.0
HKD1_k127_6535927_12 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008326 292.0
HKD1_k127_6535927_13 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006814 265.0
HKD1_k127_6535927_14 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003814 247.0
HKD1_k127_6535927_15 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000228 239.0
HKD1_k127_6535927_16 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000116 237.0
HKD1_k127_6535927_17 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000006729 235.0
HKD1_k127_6535927_18 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001089 232.0
HKD1_k127_6535927_19 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001776 218.0
HKD1_k127_6535927_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 2.264e-205 640.0
HKD1_k127_6535927_20 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000377 198.0
HKD1_k127_6535927_21 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001482 186.0
HKD1_k127_6535927_22 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000003183 179.0
HKD1_k127_6535927_23 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000006952 172.0
HKD1_k127_6535927_24 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000003903 171.0
HKD1_k127_6535927_25 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000138 133.0
HKD1_k127_6535927_26 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000009201 131.0
HKD1_k127_6535927_27 Ribosomal protein L30p/L7e K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000006695 91.0
HKD1_k127_6535927_28 Ribosomal L29 protein K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000005552 83.0
HKD1_k127_6535927_3 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 614.0
HKD1_k127_6535927_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 490.0
HKD1_k127_6535927_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 402.0
HKD1_k127_6535927_6 Male sterility protein K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 365.0
HKD1_k127_6535927_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 332.0
HKD1_k127_6535927_8 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 331.0
HKD1_k127_6535927_9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 322.0
HKD1_k127_6564622_0 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 444.0
HKD1_k127_6564622_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 291.0
HKD1_k127_6564622_2 Carbamoyl-phosphate synthase L chain ATP-binding K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000001031 243.0
HKD1_k127_6564622_3 endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000001466 179.0
HKD1_k127_6564622_4 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000001392 102.0
HKD1_k127_6564622_6 - - - - 0.00001857 47.0
HKD1_k127_657579_0 Lytic murein transglycosylase K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 548.0
HKD1_k127_657579_1 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 437.0
HKD1_k127_657579_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000008489 169.0
HKD1_k127_6584876_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1102.0
HKD1_k127_6584876_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 539.0
HKD1_k127_6584876_2 cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 403.0
HKD1_k127_6584876_3 Cell division protein K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 394.0
HKD1_k127_6584876_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 328.0
HKD1_k127_6584876_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002439 271.0
HKD1_k127_6584876_7 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000004458 212.0
HKD1_k127_6584876_8 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000001783 151.0
HKD1_k127_669868_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1729.0
HKD1_k127_669868_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 5.285e-303 935.0
HKD1_k127_669868_10 Methyltransferase small domain K15460 - 2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000000000000000008119 265.0
HKD1_k127_669868_11 May be involved in the biosynthesis of molybdopterin K03638 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000002459 261.0
HKD1_k127_669868_12 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000001683 253.0
HKD1_k127_669868_13 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001327 244.0
HKD1_k127_669868_14 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000543 243.0
HKD1_k127_669868_15 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000007386 232.0
HKD1_k127_669868_16 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000001134 179.0
HKD1_k127_669868_18 Putative prokaryotic signal transducing protein - - - 0.000000000005501 69.0
HKD1_k127_669868_2 Tetratricopeptide repeat - - - 5.245e-218 692.0
HKD1_k127_669868_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 548.0
HKD1_k127_669868_4 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 530.0
HKD1_k127_669868_6 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 446.0
HKD1_k127_669868_7 Peptidase S49 K04773,K04774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 397.0
HKD1_k127_669868_8 Phage SPO1 DNA K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 350.0
HKD1_k127_669868_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006522 266.0
HKD1_k127_6831577_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 362.0
HKD1_k127_6831577_1 receptor K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000001035 239.0
HKD1_k127_6831577_2 ATP-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000009398 219.0
HKD1_k127_6831577_3 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000009725 180.0
HKD1_k127_6831577_4 receptor K16092 - - 0.0000000000000000000000000000003769 129.0
HKD1_k127_6831577_5 receptor K16092 - - 0.000000000000003028 81.0
HKD1_k127_6831577_6 receptor K16092 - - 0.000000000000003992 76.0
HKD1_k127_6864665_0 cystathionine beta-lyase K01760 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 561.0
HKD1_k127_6864665_1 Belongs to the bacterial solute-binding protein 3 family K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 400.0
HKD1_k127_6864665_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 330.0
HKD1_k127_6864665_3 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005552 251.0
HKD1_k127_6864665_4 Sulfate ABC transporter inner membrane subunit CysT K02046 - - 0.000000000000000000000000002936 113.0
HKD1_k127_6874833_0 Elongation factor G, domain IV K02355 - - 1.693e-320 995.0
HKD1_k127_6874833_1 Aminotransferase K00812 - 2.6.1.1 1.168e-216 677.0
HKD1_k127_6874833_10 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000366 109.0
HKD1_k127_6874833_13 Major facilitator Superfamily - - - 0.0000000000003975 76.0
HKD1_k127_6874833_2 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 594.0
HKD1_k127_6874833_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 291.0
HKD1_k127_6874833_4 Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006496 258.0
HKD1_k127_6874833_5 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000005205 236.0
HKD1_k127_6874833_6 4-oxalocrotonate tautomerase - - - 0.00000000000000000000000000000000000000000000000000000000000005244 216.0
HKD1_k127_6874833_7 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000000000000000000522 179.0
HKD1_k127_6874833_8 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000000000008416 182.0
HKD1_k127_6874833_9 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000001008 169.0
HKD1_k127_6950875_0 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 588.0
HKD1_k127_6950875_1 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 551.0
HKD1_k127_6950875_2 Domain of unknown function DUF87 K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 547.0
HKD1_k127_6950875_3 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 452.0
HKD1_k127_6950875_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 389.0
HKD1_k127_6950875_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 335.0
HKD1_k127_6950875_6 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000001525 184.0
HKD1_k127_6950875_7 Protein conserved in bacteria K09937 - - 0.0000000000000002721 81.0
HKD1_k127_7047784_0 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 515.0
HKD1_k127_7047784_1 Type VI secretion system (T6SS), amidase effector protein 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 304.0
HKD1_k127_7047784_2 ATP12 chaperone protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004565 259.0
HKD1_k127_7047784_3 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000009289 259.0
HKD1_k127_7056540_0 Major Facilitator Superfamily - - - 1.623e-280 879.0
HKD1_k127_7056540_1 DinB superfamily - - - 7.713e-217 681.0
HKD1_k127_7056540_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 618.0
HKD1_k127_7056540_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 557.0
HKD1_k127_7056540_4 Patatin phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 516.0
HKD1_k127_7056540_5 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 486.0
HKD1_k127_7056540_6 Terminase RNaseH-like domain - - - 0.0000000000000000000000000000000000000000000000004725 179.0
HKD1_k127_7056540_7 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000008075 162.0
HKD1_k127_7056540_8 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000003018 136.0
HKD1_k127_7056540_9 DNA packaging K07474 - - 0.0000000003441 64.0
HKD1_k127_7064802_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 3.117e-295 919.0
HKD1_k127_7064802_1 Secreted protein K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 311.0
HKD1_k127_7064802_2 Transcription elongation factor - - - 0.000000000000000000000000000000000000000000000002286 179.0
HKD1_k127_7064802_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000001067 175.0
HKD1_k127_7064802_4 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000003401 174.0
HKD1_k127_7064802_5 - - - - 0.00000000000000000000000000000000000006205 148.0
HKD1_k127_7072090_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1501.0
HKD1_k127_7072090_1 Zinc-binding dehydrogenase K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 451.0
HKD1_k127_7072090_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000001863 196.0
HKD1_k127_7072090_11 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000004783 182.0
HKD1_k127_7072090_12 COG0822 NifU homolog involved in Fe-S cluster formation - - - 0.000000000000000000000000000000000000000000000003419 177.0
HKD1_k127_7072090_13 PAS domain - - - 0.0000000000000000000000000000000000000000000000841 177.0
HKD1_k127_7072090_14 Cupin domain - - - 0.0000000000000000000000000000000000000000000004922 171.0
HKD1_k127_7072090_15 PilZ domain - - - 0.000000000000000000000000000000000000000000112 168.0
HKD1_k127_7072090_16 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000000000000002896 158.0
HKD1_k127_7072090_17 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000001474 152.0
HKD1_k127_7072090_18 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000003199 129.0
HKD1_k127_7072090_19 Protein of unknown function (DUF3126) - - - 0.0000000000000000000003361 104.0
HKD1_k127_7072090_2 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 442.0
HKD1_k127_7072090_20 Homocysteine S-methyltransferase K00544,K00548 - 2.1.1.13,2.1.1.5 0.00000000000000000013 88.0
HKD1_k127_7072090_3 serine acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 439.0
HKD1_k127_7072090_4 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 364.0
HKD1_k127_7072090_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 352.0
HKD1_k127_7072090_6 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 314.0
HKD1_k127_7072090_7 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002754 256.0
HKD1_k127_7072090_8 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000004308 242.0
HKD1_k127_7072090_9 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000004722 230.0
HKD1_k127_7079185_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 591.0
HKD1_k127_7079185_1 Orn DAP Arg decarboxylase 2 K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 584.0
HKD1_k127_7079185_10 gag-polyprotein putative aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000000000000000002344 199.0
HKD1_k127_7079185_11 relative of glutathione S-transferase, MAPEG superfamily K07136 - - 0.00000000000000000000000000000000000002287 149.0
HKD1_k127_7079185_13 Protein of unknown function (DUF1289) K06938 - - 0.000000000000004443 81.0
HKD1_k127_7079185_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 554.0
HKD1_k127_7079185_3 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 454.0
HKD1_k127_7079185_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 410.0
HKD1_k127_7079185_5 glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 291.0
HKD1_k127_7079185_6 helix_turn_helix ASNC type K05800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001375 277.0
HKD1_k127_7079185_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001765 276.0
HKD1_k127_7079185_8 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 261.0
HKD1_k127_7079185_9 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000000000000000000000000000000000000000000000000000004267 233.0
HKD1_k127_7095838_0 Putative transposase - - - 1.517e-232 722.0
HKD1_k127_7095838_1 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 534.0
HKD1_k127_7124974_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 558.0
HKD1_k127_7124974_1 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 304.0
HKD1_k127_7124974_2 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000046 271.0
HKD1_k127_7124974_3 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005121 255.0
HKD1_k127_7124974_4 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000002657 244.0
HKD1_k127_7124974_5 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000000000000007649 176.0
HKD1_k127_7124974_6 Universal stress protein - - - 0.00000000000000000000000000000000000000000007109 165.0
HKD1_k127_7124974_7 Cupredoxin-like domain - - - 0.0000000000000000000000016 103.0
HKD1_k127_7148178_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1414.0
HKD1_k127_7148178_1 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 1.316e-241 749.0
HKD1_k127_7148178_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 590.0
HKD1_k127_7148178_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 577.0
HKD1_k127_7148178_4 paraquat-inducible protein A K03808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 421.0
HKD1_k127_7148178_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 362.0
HKD1_k127_7148178_6 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 295.0
HKD1_k127_7148178_7 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006563 241.0
HKD1_k127_7148178_8 - - - - 0.000000000000000000000000000000000000000000000000000000000004487 222.0
HKD1_k127_7148178_9 Protein of unknown function (DUF992) - - - 0.00000000000000000000000000000000000000002151 158.0
HKD1_k127_7152863_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 576.0
HKD1_k127_7152863_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 385.0
HKD1_k127_7152863_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 319.0
HKD1_k127_7152863_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000000000000002792 220.0
HKD1_k127_7152863_4 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000005543 130.0
HKD1_k127_7161704_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 7.424e-201 649.0
HKD1_k127_7161704_1 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 617.0
HKD1_k127_7161704_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000000000000000001714 192.0
HKD1_k127_7161704_11 protein dimerization activity K03746 - - 0.0000000000000000000000000000000000000003821 151.0
HKD1_k127_7161704_12 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000002231 147.0
HKD1_k127_7161704_13 Cytochrome c - - - 0.00000000000000000000000000001312 121.0
HKD1_k127_7161704_2 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 559.0
HKD1_k127_7161704_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 362.0
HKD1_k127_7161704_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 361.0
HKD1_k127_7161704_5 PFAM peptidase U6 penicillin-insensitive murein endopeptidase K07261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 350.0
HKD1_k127_7161704_6 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006224 269.0
HKD1_k127_7161704_7 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000004349 258.0
HKD1_k127_7161704_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000002021 231.0
HKD1_k127_7181787_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 522.0
HKD1_k127_7181787_1 Aminotransferase class I and II K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 501.0
HKD1_k127_7181787_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 320.0
HKD1_k127_7181787_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002056 265.0
HKD1_k127_7181787_4 Transcriptional regulator GntR family K03710 - - 0.0000000000000000000000000000000000000000000000004325 183.0
HKD1_k127_7206449_0 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 361.0
HKD1_k127_7206449_1 COG0491 Zn-dependent hydrolases, including glyoxylases - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 323.0
HKD1_k127_7206449_2 - - - - 0.0000000000000000000000000000000000000000000000000004504 193.0
HKD1_k127_7206449_3 Predicted small integral membrane protein (DUF2165) - - - 0.000000000000000000000000000000000000000000000000000652 188.0
HKD1_k127_7206449_4 - - - - 0.00000000000000000000000000000003097 131.0
HKD1_k127_7206449_6 Belongs to the 'phage' integrase family - - - 0.000000000573 63.0
HKD1_k127_7212633_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1170.0
HKD1_k127_7212633_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 1.526e-229 720.0
HKD1_k127_7212633_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 587.0
HKD1_k127_7212633_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 485.0
HKD1_k127_7212633_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 386.0
HKD1_k127_7212633_5 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 366.0
HKD1_k127_7212633_6 COG0607 Rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000001015 204.0
HKD1_k127_7212633_9 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000004347 92.0
HKD1_k127_7252463_0 ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 595.0
HKD1_k127_7252463_1 FAD binding domain K03185 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 484.0
HKD1_k127_7252463_2 Acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 431.0
HKD1_k127_7252463_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 404.0
HKD1_k127_7252463_4 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000000001175 213.0
HKD1_k127_7252463_5 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000003066 204.0
HKD1_k127_7252463_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000414 176.0
HKD1_k127_7252463_7 Transcriptional regulator, Crp Fnr family - - - 0.0000000000003067 76.0
HKD1_k127_7285454_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0 1218.0
HKD1_k127_7285454_1 Histidine kinase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 3.338e-309 969.0
HKD1_k127_7285454_10 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002455 263.0
HKD1_k127_7285454_11 Glutamine amido-transferase K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000008426 262.0
HKD1_k127_7285454_12 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000009089 250.0
HKD1_k127_7285454_13 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.000000000000000000000000000000000000000000000000000000000005378 210.0
HKD1_k127_7285454_14 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702 - 0.000000000000000000000000000000000000000002846 158.0
HKD1_k127_7285454_15 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000004702 141.0
HKD1_k127_7285454_16 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.00000000000000000003317 92.0
HKD1_k127_7285454_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 2.591e-267 828.0
HKD1_k127_7285454_3 Signal transduction histidine kinase K14980 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 616.0
HKD1_k127_7285454_4 Threonylcarbamoyl adenosine biosynthesis protein TsaE K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 578.0
HKD1_k127_7285454_5 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 504.0
HKD1_k127_7285454_6 Transcriptional regulatory protein, C terminal K14981 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 447.0
HKD1_k127_7285454_7 glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 385.0
HKD1_k127_7285454_8 Nucleotidyl transferase K00966,K00992 - 2.7.7.13,2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 347.0
HKD1_k127_7285454_9 pyridoxamine 5'-phosphate K07226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007403 275.0
HKD1_k127_7386328_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1504.0
HKD1_k127_7386328_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 563.0
HKD1_k127_7386328_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 436.0
HKD1_k127_7386328_3 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 398.0
HKD1_k127_7386328_4 Alpha beta hydrolase K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 378.0
HKD1_k127_7386328_5 HlyD membrane-fusion protein of T1SS K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 345.0
HKD1_k127_7386328_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005665 263.0
HKD1_k127_7386328_7 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000000000009513 175.0
HKD1_k127_7386328_8 Cellulose biosynthesis protein BcsS - - - 0.000000000000000000000000002261 117.0
HKD1_k127_73978_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 470.0
HKD1_k127_73978_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 438.0
HKD1_k127_73978_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 415.0
HKD1_k127_73978_3 Protein of unknown function (DUF1009) K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 348.0
HKD1_k127_73978_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 294.0
HKD1_k127_7398009_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03696 - - 9.329e-200 664.0
HKD1_k127_7398009_1 Gram-negative porin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007388 259.0
HKD1_k127_7405931_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 9.372e-278 856.0
HKD1_k127_7405931_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 456.0
HKD1_k127_7405931_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 379.0
HKD1_k127_7405931_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003929 275.0
HKD1_k127_7405931_4 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001476 270.0
HKD1_k127_7405931_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001697 254.0
HKD1_k127_7405931_6 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000003104 213.0
HKD1_k127_7405931_7 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000004631 203.0
HKD1_k127_7417837_0 GTP-binding protein K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0 1042.0
HKD1_k127_7417837_1 Helicase - - - 5.993e-209 657.0
HKD1_k127_7417837_2 Major facilitator Superfamily K03761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 603.0
HKD1_k127_7417837_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000486 204.0
HKD1_k127_7417837_4 Peptidase propeptide and YPEB domain - - - 0.0000000000000000007561 89.0
HKD1_k127_7451739_0 Glutamate synthase K00265 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 0.0 2615.0
HKD1_k127_7451739_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 1.578e-253 787.0
HKD1_k127_7451739_2 Alpha beta hydrolase fold K01048 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 419.0
HKD1_k127_7451739_3 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 414.0
HKD1_k127_7451739_4 inositol mono-phosphatase K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 332.0
HKD1_k127_7451739_5 Response regulator receiver K13589 - - 0.0000000000000000000000000000000000000000000000000000000000001624 219.0
HKD1_k127_7451739_6 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.0000000000000000000000000000000000000000000000000000000265 203.0
HKD1_k127_7456982_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 1.299e-307 959.0
HKD1_k127_7456982_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K13926 - - 1.836e-238 750.0
HKD1_k127_7456982_10 ChaB K06197 - - 0.000000000000000000000000004188 111.0
HKD1_k127_7456982_11 - - - - 0.0000000000000000000000059 104.0
HKD1_k127_7456982_12 IS1 transposase - - - 0.0000000000000000000005576 97.0
HKD1_k127_7456982_13 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.000000003532 65.0
HKD1_k127_7456982_14 transferase activity, transferring glycosyl groups - - - 0.0002932 45.0
HKD1_k127_7456982_2 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 457.0
HKD1_k127_7456982_3 secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 439.0
HKD1_k127_7456982_4 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 428.0
HKD1_k127_7456982_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K13926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 396.0
HKD1_k127_7456982_6 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000001656 204.0
HKD1_k127_7456982_7 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000000000000000000000000000000000000000002034 196.0
HKD1_k127_7456982_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000005944 172.0
HKD1_k127_7456982_9 COG1544 Ribosome-associated protein Y (PSrp-1) - - - 0.000000000000000000000000000000005533 131.0
HKD1_k127_7483484_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 539.0
HKD1_k127_7483484_1 Sodium:solute symporter family K14393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 309.0
HKD1_k127_7483484_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000001421 104.0
HKD1_k127_7483484_3 Domain of unknown function (DUF4212) - - - 0.0000006295 55.0
HKD1_k127_7485258_0 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 8.311e-219 684.0
HKD1_k127_7485258_1 Cupin - - - 0.0000000000000000000000000000000000000000000003213 173.0
HKD1_k127_7485258_2 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000001052 169.0
HKD1_k127_7487710_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 565.0
HKD1_k127_7487710_1 cytochrome c biogenesis protein K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 364.0
HKD1_k127_7487710_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 296.0
HKD1_k127_7490052_0 poly(R)-hydroxyalkanoic acid synthase K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.281e-298 926.0
HKD1_k127_7490052_1 Aminotransferase K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 3.416e-231 719.0
HKD1_k127_7490052_2 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 599.0
HKD1_k127_7490052_3 fructose-1,6-bisphosphatase K02446,K11532 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 524.0
HKD1_k127_7490052_4 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 521.0
HKD1_k127_7490052_5 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 427.0
HKD1_k127_7490052_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 415.0
HKD1_k127_7490052_7 PFAM helix-turn-helix- domain containing protein AraC type K07506 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 346.0
HKD1_k127_7490052_8 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000006235 221.0
HKD1_k127_7499737_0 phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1224.0
HKD1_k127_7499737_1 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 3.319e-223 707.0
HKD1_k127_7499737_10 MobA-like NTP transferase domain K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000867 185.0
HKD1_k127_7499737_11 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000000004025 154.0
HKD1_k127_7499737_12 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000003656 126.0
HKD1_k127_7499737_13 molybdopterin-guanine dinucleotide biosynthesis protein K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000006068 88.0
HKD1_k127_7499737_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 598.0
HKD1_k127_7499737_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0031317,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0071702,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 560.0
HKD1_k127_7499737_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 470.0
HKD1_k127_7499737_5 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 404.0
HKD1_k127_7499737_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 284.0
HKD1_k127_7499737_7 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002188 246.0
HKD1_k127_7499737_8 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000001703 233.0
HKD1_k127_7499737_9 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000001333 196.0
HKD1_k127_7503165_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 317.0
HKD1_k127_7503165_1 Invasion associated locus B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002877 267.0
HKD1_k127_7503165_2 Cellulose biosynthesis protein BcsS - - - 0.0000000000000000000000000000001483 127.0
HKD1_k127_7503165_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.000000000000000000000000005599 113.0
HKD1_k127_7558680_0 Alkaline phosphatase homologues K01077 - 3.1.3.1 3.68e-230 727.0
HKD1_k127_7558680_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 392.0
HKD1_k127_7558680_2 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002622 278.0
HKD1_k127_7558680_3 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000001979 135.0
HKD1_k127_7558680_4 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000008587 123.0
HKD1_k127_7558680_5 UTRA - - - 0.00001041 48.0
HKD1_k127_7576731_0 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 311.0
HKD1_k127_7576731_1 HWE histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000395 302.0
HKD1_k127_7576731_2 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000005438 226.0
HKD1_k127_7576731_3 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000000000001287 104.0
HKD1_k127_7630144_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 522.0
HKD1_k127_7630144_1 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 361.0
HKD1_k127_7630144_2 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 300.0
HKD1_k127_7630144_4 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00003657 46.0
HKD1_k127_7630144_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0001727 45.0
HKD1_k127_7645612_0 ABC transporter C-terminal domain K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 5.265e-265 828.0
HKD1_k127_7645612_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.779e-208 652.0
HKD1_k127_7817214_0 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 482.0
HKD1_k127_7817214_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 458.0
HKD1_k127_7817214_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000004233 196.0
HKD1_k127_7817214_11 Phage integrase family - - - 0.0000000000000000000000000000000000000000157 158.0
HKD1_k127_7817214_12 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000000000000000000000000000000000009785 143.0
HKD1_k127_7817214_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000002036 132.0
HKD1_k127_7817214_2 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 392.0
HKD1_k127_7817214_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 361.0
HKD1_k127_7817214_4 Disulphide bond corrector protein DsbC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002997 259.0
HKD1_k127_7817214_5 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000008257 248.0
HKD1_k127_7817214_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009883 248.0
HKD1_k127_7817214_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000005993 240.0
HKD1_k127_7817214_8 chitinase - - - 0.000000000000000000000000000000000000000000000000000000000000000002062 254.0
HKD1_k127_7817214_9 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000001963 198.0
HKD1_k127_7990946_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 7.914e-319 987.0
HKD1_k127_7990946_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 5.463e-232 732.0
HKD1_k127_7990946_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 404.0
HKD1_k127_7990946_3 belongs to the carbohydrate kinase PfkB family K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 342.0
HKD1_k127_80047_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 482.0
HKD1_k127_80047_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 458.0
HKD1_k127_80047_2 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 453.0
HKD1_k127_80047_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 359.0
HKD1_k127_80047_4 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 338.0
HKD1_k127_80047_5 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000000002204 180.0
HKD1_k127_80047_6 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 0.00000000000000000000000003261 110.0
HKD1_k127_8033664_0 Acetolactate synthase K01652 - 2.2.1.6 0.0 1084.0
HKD1_k127_8033664_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 7.591e-285 882.0
HKD1_k127_8033664_10 - - - - 0.0001651 44.0
HKD1_k127_8033664_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.275e-196 619.0
HKD1_k127_8033664_3 Rod shape-determining protein (MreB) K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 464.0
HKD1_k127_8033664_4 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 439.0
HKD1_k127_8033664_5 Acetolactate synthase K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 299.0
HKD1_k127_8033664_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000002138 241.0
HKD1_k127_8033664_7 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000007263 187.0
HKD1_k127_8033664_9 PilZ domain - - - 0.0000000001514 63.0
HKD1_k127_821754_0 LppC putative lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 392.0
HKD1_k127_821754_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 368.0
HKD1_k127_821754_2 protein conserved in bacteria K09974 - - 0.000000000000000000000000000000000000000000000000000000000000004883 234.0
HKD1_k127_821754_3 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000001436 147.0
HKD1_k127_821754_4 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000002208 127.0
HKD1_k127_821754_5 O-methyltransferase K09846 - 2.1.1.210 0.00000000000002688 74.0
HKD1_k127_821754_6 Belongs to the pirin family K06911 - - 0.0000000000001015 76.0
HKD1_k127_91550_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 546.0
HKD1_k127_91550_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 540.0
HKD1_k127_91550_11 Acetyltransferase - - - 0.00006221 53.0
HKD1_k127_91550_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 484.0
HKD1_k127_91550_3 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 338.0
HKD1_k127_91550_4 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 299.0
HKD1_k127_91550_5 rRNA binding K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000002088 214.0
HKD1_k127_91550_6 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000001484 196.0
HKD1_k127_91550_7 Domain of unknown function (DUF4287) - - - 0.000000000000000000000000000000000000000000000004377 180.0
HKD1_k127_91550_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000009465 135.0
HKD1_k127_92641_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1300.0
HKD1_k127_92641_1 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 472.0
HKD1_k127_92641_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000009717 223.0
HKD1_k127_92641_3 MAPEG family - - - 0.00000000000000000000000000000000001848 139.0
HKD1_k127_92641_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.00000000000000000000000001349 115.0
HKD1_k127_93263_0 Ligand-gated ion channel K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 434.0
HKD1_k127_93263_1 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 335.0
HKD1_k127_93263_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001536 268.0
HKD1_k127_93263_3 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001178 250.0
HKD1_k127_93263_4 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000001063 234.0
HKD1_k127_93263_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.0000000000000000000000000000000000000000000000000000005321 196.0
HKD1_k127_93263_6 - - - - 0.000000000000000000000000000000000000000000000005114 179.0
HKD1_k127_93263_7 Lytic transglycolase K03642 - - 0.000000000000000000000000003172 115.0