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Overview

ID MAG01737
Name HKD1_bin.54
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Methylomirabilota
Class Methylomirabilia
Order Methylomirabilales
Family 2-02-FULL-66-22
Genus 2-02-FULL-66-22
Species
Assembly information
Completeness (%) 100.0
Contamination (%) 6.87
GC content (%) 64.0
N50 (bp) 17,053
Genome size (bp) 5,604,775

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes5000

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1004362_0 self proteolysis - - - 0.00000000000000000000000000000000000000000000003188 184.0
HKD1_k127_1004362_1 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.000000002076 58.0
HKD1_k127_1004362_2 - - - - 0.000001225 51.0
HKD1_k127_1019236_0 Sulfate permease family - - - 1.387e-235 742.0
HKD1_k127_1019236_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 462.0
HKD1_k127_1019236_2 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 315.0
HKD1_k127_1019236_3 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000001 225.0
HKD1_k127_1019236_4 Cysteine rich repeat - - - 0.00000000005086 69.0
HKD1_k127_1026835_0 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 602.0
HKD1_k127_1026835_1 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 546.0
HKD1_k127_1026835_10 endonuclease III K00558,K01962,K01963,K03575 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.37,2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000001157 236.0
HKD1_k127_1026835_11 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000008685 182.0
HKD1_k127_1026835_12 methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.0000000000000000000000000000000000006454 153.0
HKD1_k127_1026835_13 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000002189 133.0
HKD1_k127_1026835_14 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000501 127.0
HKD1_k127_1026835_15 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000002133 119.0
HKD1_k127_1026835_16 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.0000000000000000000000000002404 113.0
HKD1_k127_1026835_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000005074 117.0
HKD1_k127_1026835_18 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000008691 114.0
HKD1_k127_1026835_19 HD domain K07814 - - 0.0000000000000000000000002503 115.0
HKD1_k127_1026835_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 535.0
HKD1_k127_1026835_21 peroxiredoxin activity K02199 - - 0.00000000000005313 75.0
HKD1_k127_1026835_22 Phage-shock protein K03973 - - 0.0000005374 55.0
HKD1_k127_1026835_23 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K06196 - - 0.000001489 54.0
HKD1_k127_1026835_3 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 514.0
HKD1_k127_1026835_4 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 432.0
HKD1_k127_1026835_5 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 399.0
HKD1_k127_1026835_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 346.0
HKD1_k127_1026835_7 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000003082 262.0
HKD1_k127_1026835_8 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001136 265.0
HKD1_k127_1026835_9 cell wall glycoprotein biosynthetic process K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000009018 242.0
HKD1_k127_103605_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 567.0
HKD1_k127_103605_1 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000002065 215.0
HKD1_k127_1038432_0 Bacterial extracellular solute-binding protein K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 396.0
HKD1_k127_1038432_1 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000003957 152.0
HKD1_k127_1041383_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1012.0
HKD1_k127_1041383_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 6.897e-206 649.0
HKD1_k127_1041383_2 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 360.0
HKD1_k127_1041459_0 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007396 268.0
HKD1_k127_1041459_1 site-specific DNA-methyltransferase (adenine-specific) activity - - - 0.000000000000000000002608 94.0
HKD1_k127_1044773_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0 1050.0
HKD1_k127_1044773_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K12266 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 578.0
HKD1_k127_1044773_10 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000007509 220.0
HKD1_k127_1044773_11 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000000000000000000000000000000005009 213.0
HKD1_k127_1044773_12 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000003256 206.0
HKD1_k127_1044773_13 Uncharacterized conserved protein (DUF2249) K07322 - - 0.000000000000000000000000000000000000000000000000000002168 197.0
HKD1_k127_1044773_14 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000004483 147.0
HKD1_k127_1044773_15 Transcriptional regulator K05799,K07746 - - 0.00000000000000000000000000000000002117 146.0
HKD1_k127_1044773_16 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000003094 117.0
HKD1_k127_1044773_2 Transketolase, central region K11381,K21417 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 406.0
HKD1_k127_1044773_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 394.0
HKD1_k127_1044773_4 conserved protein (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 384.0
HKD1_k127_1044773_5 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 380.0
HKD1_k127_1044773_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 317.0
HKD1_k127_1044773_7 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 315.0
HKD1_k127_1044773_8 major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000566 234.0
HKD1_k127_1044773_9 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000001455 225.0
HKD1_k127_1047301_0 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 607.0
HKD1_k127_1047301_1 Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 409.0
HKD1_k127_1047301_2 ISPsy14, transposition helper protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 300.0
HKD1_k127_1047301_3 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000008602 162.0
HKD1_k127_1047301_4 COG2801 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000001815 137.0
HKD1_k127_1047301_5 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000001544 128.0
HKD1_k127_1047301_6 transmembrane transport K02025,K15771 - - 0.00000000000000000000001878 107.0
HKD1_k127_1047301_7 FCD - - - 0.00000000000000000009126 98.0
HKD1_k127_1047301_8 COG1175 ABC-type sugar transport systems permease components K02025 - - 0.000000000001126 72.0
HKD1_k127_1047301_9 Transcriptional regulator - - - 0.00000128 54.0
HKD1_k127_1049473_0 Tripartite tricarboxylate transporter TctA family K07793 - - 4.665e-195 621.0
HKD1_k127_1049473_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 350.0
HKD1_k127_1049473_2 2-dehydro-3-deoxy-phosphogluconate aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000005631 174.0
HKD1_k127_1049473_3 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000002156 126.0
HKD1_k127_1049473_4 Cytidylate kinase-like family - - - 0.000000000000000000000002997 113.0
HKD1_k127_1049473_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000005031 60.0
HKD1_k127_1059101_0 L-fucose isomerase K01818 - 5.3.1.25,5.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 607.0
HKD1_k127_1059101_1 Tripartite tricarboxylate transporter TctA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 559.0
HKD1_k127_1059101_10 ABC-type sugar transport system periplasmic component K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 350.0
HKD1_k127_1059101_11 amino acid transport K01713,K02030 - 4.2.1.51,4.2.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 340.0
HKD1_k127_1059101_12 ABC-type sugar transport system periplasmic component K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 344.0
HKD1_k127_1059101_13 C4-dicarboxylate ABC transporter permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 332.0
HKD1_k127_1059101_14 Carbohydrate ABC transporter membrane protein 2, CUT1 family K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 306.0
HKD1_k127_1059101_15 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 305.0
HKD1_k127_1059101_16 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001954 274.0
HKD1_k127_1059101_17 helix_turn _helix lactose operon repressor K02525,K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001096 275.0
HKD1_k127_1059101_18 PFAM short-chain dehydrogenase reductase SDR K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 268.0
HKD1_k127_1059101_19 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008727 274.0
HKD1_k127_1059101_2 mannitol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 506.0
HKD1_k127_1059101_20 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000121 265.0
HKD1_k127_1059101_21 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006372 256.0
HKD1_k127_1059101_22 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005566 246.0
HKD1_k127_1059101_23 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000002645 234.0
HKD1_k127_1059101_24 ribonucleoside-diphosphate reductase activity K07735 - - 0.000000000000000000000000000000000000000000000000000000000000003575 227.0
HKD1_k127_1059101_25 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000004966 206.0
HKD1_k127_1059101_26 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000002163 195.0
HKD1_k127_1059101_27 Belongs to the AAA ATPase family K13525 - - 0.000000000000000000000000000000000000000000000003781 185.0
HKD1_k127_1059101_28 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000003155 178.0
HKD1_k127_1059101_29 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000006042 167.0
HKD1_k127_1059101_3 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 483.0
HKD1_k127_1059101_30 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000000008044 159.0
HKD1_k127_1059101_31 - - - - 0.000000000000000000000000000000000001148 141.0
HKD1_k127_1059101_32 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.000000000000000000000000000000001063 131.0
HKD1_k127_1059101_33 - - - - 0.00000000000000000000000000000006776 130.0
HKD1_k127_1059101_34 CoA binding domain K06929 - - 0.0000000000000000000000000000001082 128.0
HKD1_k127_1059101_35 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.000000000000000000000000002664 118.0
HKD1_k127_1059101_36 - - - - 0.0000000000000000000000001099 108.0
HKD1_k127_1059101_37 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000002387 105.0
HKD1_k127_1059101_39 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000002581 99.0
HKD1_k127_1059101_4 Pyrrolo-quinoline quinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 464.0
HKD1_k127_1059101_40 UTRA K03486,K03710 - - 0.0000000000000002518 84.0
HKD1_k127_1059101_41 - - - - 0.0000000000003319 74.0
HKD1_k127_1059101_42 - - - - 0.0000000004357 69.0
HKD1_k127_1059101_43 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000005747 64.0
HKD1_k127_1059101_44 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000008562 66.0
HKD1_k127_1059101_45 - - - - 0.0000001105 59.0
HKD1_k127_1059101_46 PD-(D/E)XK nuclease superfamily K09124 - - 0.000001602 58.0
HKD1_k127_1059101_5 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 441.0
HKD1_k127_1059101_6 carbohydrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 423.0
HKD1_k127_1059101_7 Belongs to the FGGY kinase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 430.0
HKD1_k127_1059101_8 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 369.0
HKD1_k127_1059101_9 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 351.0
HKD1_k127_1077488_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.472e-317 984.0
HKD1_k127_1077488_1 Receptor family ligand binding region - - - 8.831e-212 662.0
HKD1_k127_1077488_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000001078 95.0
HKD1_k127_1077488_3 Mo-molybdopterin cofactor metabolic process - - - 0.000000000000000002875 86.0
HKD1_k127_1077488_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000007257 78.0
HKD1_k127_1083200_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K00344,K00966,K01840,K03431,K15778,K16881 - 1.6.5.5,2.7.7.13,5.4.2.10,5.4.2.2,5.4.2.8 0.0 1135.0
HKD1_k127_1083200_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.45e-248 778.0
HKD1_k127_1083200_10 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002834 274.0
HKD1_k127_1083200_11 Domain of unknown function (DUF1732) - GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000007006 261.0
HKD1_k127_1083200_12 Essential for recycling GMP and indirectly, cGMP K00942,K01591 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000008523 246.0
HKD1_k127_1083200_13 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000001219 248.0
HKD1_k127_1083200_14 Bacterial extracellular solute-binding protein, family 7 K11688 - - 0.00000000000000000000000000000000000000000000000000000005846 210.0
HKD1_k127_1083200_15 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.00000000000000000000000000000000000000004053 159.0
HKD1_k127_1083200_16 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000003206 130.0
HKD1_k127_1083200_17 Putative regulatory protein - - - 0.00000000000000000000000000001725 120.0
HKD1_k127_1083200_18 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.00000000000000000002663 98.0
HKD1_k127_1083200_19 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000001225 95.0
HKD1_k127_1083200_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.998e-195 618.0
HKD1_k127_1083200_20 VanZ like family - - - 0.0000000000000000004217 97.0
HKD1_k127_1083200_21 Ribbon-helix-helix protein, copG family - - - 0.00000000000000009904 81.0
HKD1_k127_1083200_22 cell cycle K05589,K12065,K13052 - - 0.00000000000002999 77.0
HKD1_k127_1083200_23 Malate/L-lactate dehydrogenase - - - 0.0000000000512 65.0
HKD1_k127_1083200_24 Tripartite tricarboxylate transporter TctB family - - - 0.0002029 53.0
HKD1_k127_1083200_3 Tripartite tricarboxylate transporter TctA family K07793 - - 1.151e-194 621.0
HKD1_k127_1083200_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 492.0
HKD1_k127_1083200_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 407.0
HKD1_k127_1083200_6 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 375.0
HKD1_k127_1083200_7 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 336.0
HKD1_k127_1083200_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 327.0
HKD1_k127_1083200_9 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 323.0
HKD1_k127_1084799_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1025.0
HKD1_k127_1084799_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 537.0
HKD1_k127_1084799_10 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000004942 117.0
HKD1_k127_1084799_11 - - - - 0.000000000000000000000375 105.0
HKD1_k127_1084799_12 YMGG-like Gly-zipper - - - 0.0000000000000000000003958 102.0
HKD1_k127_1084799_13 mRNA binding - - - 0.0000000005811 60.0
HKD1_k127_1084799_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 376.0
HKD1_k127_1084799_3 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 333.0
HKD1_k127_1084799_4 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002928 279.0
HKD1_k127_1084799_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006489 252.0
HKD1_k127_1084799_6 succinate dehydrogenase K00241 - - 0.00000000000000000000000000000000000000000000000000000000000008936 222.0
HKD1_k127_1084799_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000003785 212.0
HKD1_k127_1084799_8 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000001552 171.0
HKD1_k127_1084799_9 signal transduction histidine kinase K07716 - 2.7.13.3 0.00000000000000000000000000000000000002109 167.0
HKD1_k127_1098227_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 429.0
HKD1_k127_1098227_1 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000000000000000000000002452 220.0
HKD1_k127_1098227_2 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000000000000000003518 193.0
HKD1_k127_1098227_3 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000008583 160.0
HKD1_k127_1098227_4 Redoxin domain protein - - - 0.0000000000000000000000000000000000734 139.0
HKD1_k127_1098227_5 - K04085 - - 0.000000000000001058 85.0
HKD1_k127_1098227_6 Belongs to the 'phage' integrase family K14059 - - 0.000000000001189 70.0
HKD1_k127_1123002_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.52e-205 650.0
HKD1_k127_1123002_1 Aldo/keto reductase family K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004566 262.0
HKD1_k127_1123002_2 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000003831 238.0
HKD1_k127_1123002_3 - - - - 0.000000000000000000000000000000000000000000000001127 185.0
HKD1_k127_1123002_4 PFAM ABC transporter related K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000003267 167.0
HKD1_k127_1123002_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000004221 140.0
HKD1_k127_1123002_6 PFAM Xylose isomerase - - - 0.0000000000000000000000000000001303 134.0
HKD1_k127_1123002_7 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000002707 70.0
HKD1_k127_1123002_8 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000005478 59.0
HKD1_k127_1134650_0 sptr a7nhu5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 432.0
HKD1_k127_1134650_1 Insertion element 4 transposase N-terminal - - - 0.0000000000000001683 87.0
HKD1_k127_1134650_2 PFAM Rhodopirellula transposase - - - 0.000000000002285 80.0
HKD1_k127_1137029_0 Thiamine pyrophosphate enzyme, central K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 449.0
HKD1_k127_1137029_1 Glycoprotease family K01409,K14742 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000001632 193.0
HKD1_k127_1137307_0 Cytochrome c554 and c-prime - - - 2.389e-246 784.0
HKD1_k127_1137307_1 drug resistance transporter, EmrB QacA subfamily K03446 - - 4.877e-197 627.0
HKD1_k127_1137307_2 D-galactarate dehydratase / Altronate hydrolase, C terminus K16850 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 501.0
HKD1_k127_1137307_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 435.0
HKD1_k127_1137307_4 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 346.0
HKD1_k127_1137307_5 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000356 265.0
HKD1_k127_1137307_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000001113 230.0
HKD1_k127_1137307_7 Protein of unknown function (DUF992) - - - 0.000000000000000000000000002571 120.0
HKD1_k127_1140320_0 PFAM transposase, IS4 family protein - - - 0.00000000000000000000002932 113.0
HKD1_k127_1156973_0 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000003157 180.0
HKD1_k127_1156973_1 COGs COG4293 conserved - - - 0.00000000000000000000000000000000000000000000004954 177.0
HKD1_k127_1156973_2 CbiX K03794 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.4 0.0000000000000000000000000003686 119.0
HKD1_k127_1156973_3 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.00000005049 54.0
HKD1_k127_1156973_4 Probable molybdopterin binding domain - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0008150,GO:0008152,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0055114 - 0.00006612 46.0
HKD1_k127_117831_0 Predicted Permease Membrane Region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 509.0
HKD1_k127_117831_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 374.0
HKD1_k127_117831_2 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000002965 231.0
HKD1_k127_117831_3 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000001302 189.0
HKD1_k127_117831_4 - - - - 0.000000000000000000000000000000000004329 144.0
HKD1_k127_1182715_0 protein conserved in bacteria K07793 - - 4.569e-251 781.0
HKD1_k127_1182715_1 Dehydratase family K01687,K16786 - 4.2.1.9 2.422e-250 784.0
HKD1_k127_1182715_10 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000003892 249.0
HKD1_k127_1182715_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000009644 230.0
HKD1_k127_1182715_12 Vacuole effluxer Atg22 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000241 240.0
HKD1_k127_1182715_13 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000000000000000000001291 218.0
HKD1_k127_1182715_14 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000008726 204.0
HKD1_k127_1182715_15 - - - - 0.000000000000000000000000000000000000000000000001297 181.0
HKD1_k127_1182715_16 PFAM 4Fe-4S K00196 - - 0.000000000000000000000000000000000000001564 154.0
HKD1_k127_1182715_17 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000007387 140.0
HKD1_k127_1182715_18 MazG-like family - - - 0.00000000000000000000000000008355 119.0
HKD1_k127_1182715_19 - - - - 0.0000000000000000000000005632 105.0
HKD1_k127_1182715_2 MmgE/PrpD family - - - 1.967e-210 677.0
HKD1_k127_1182715_20 Tetratricopeptide TPR_2 repeat protein K12600 - - 0.000000000000000000000002768 120.0
HKD1_k127_1182715_21 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000006409 101.0
HKD1_k127_1182715_22 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000009428 78.0
HKD1_k127_1182715_23 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000000000009219 80.0
HKD1_k127_1182715_24 - - - - 0.00000000000007026 82.0
HKD1_k127_1182715_25 Drug exporters of the RND superfamily - - - 0.00001868 49.0
HKD1_k127_1182715_3 Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 603.0
HKD1_k127_1182715_4 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 539.0
HKD1_k127_1182715_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 436.0
HKD1_k127_1182715_6 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 398.0
HKD1_k127_1182715_7 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 303.0
HKD1_k127_1182715_8 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004552 277.0
HKD1_k127_1182715_9 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001027 282.0
HKD1_k127_1223524_0 PFAM N-6 DNA methylase K03427 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 486.0
HKD1_k127_1223524_1 Belongs to the LDH2 MDH2 oxidoreductase family K00073 - 1.1.1.350 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 298.0
HKD1_k127_1223524_2 PIN domain - - - 0.0000000000000000000000000000000000000000000004953 169.0
HKD1_k127_1223524_3 Filamentation induced by cAMP protein fic - - - 0.00000000000000000000000199 105.0
HKD1_k127_1223524_4 SpoVT / AbrB like domain - - - 0.00000000000000000000004537 104.0
HKD1_k127_1228245_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1491.0
HKD1_k127_1234553_0 Proteasomal ATPase OB/ID domain K07184,K07777,K12065,K13525,K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 2.7.13.3 1.46e-255 802.0
HKD1_k127_1234553_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 9.945e-219 684.0
HKD1_k127_1234553_10 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000004873 193.0
HKD1_k127_1234553_11 NUDIX domain - - - 0.0000000000000000000000000000000000000001956 156.0
HKD1_k127_1234553_12 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000002076 130.0
HKD1_k127_1234553_13 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000006781 126.0
HKD1_k127_1234553_14 von Willebrand factor, type A - - - 0.00000000000000000000000000006411 127.0
HKD1_k127_1234553_15 Pup-like protein K13570 - - 0.00000000000001106 76.0
HKD1_k127_1234553_16 Regulatory protein, FmdB family - - - 0.00000000000004836 73.0
HKD1_k127_1234553_2 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 591.0
HKD1_k127_1234553_3 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 399.0
HKD1_k127_1234553_4 conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 345.0
HKD1_k127_1234553_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 309.0
HKD1_k127_1234553_6 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000004255 264.0
HKD1_k127_1234553_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009716 259.0
HKD1_k127_1234553_8 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002985 228.0
HKD1_k127_1234553_9 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.00000000000000000000000000000000000000000000000000000000000864 214.0
HKD1_k127_1265550_0 dipeptide transport K02035 - - 1.95e-216 684.0
HKD1_k127_1265550_1 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 428.0
HKD1_k127_1265550_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 413.0
HKD1_k127_1265550_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 357.0
HKD1_k127_1266046_0 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 330.0
HKD1_k127_1266046_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000881 224.0
HKD1_k127_1266046_2 regulatory protein, gntR - - - 0.000000000000000000000000000000000000000000000000002893 194.0
HKD1_k127_1266046_3 PFAM regulatory protein ArsR K03892 - - 0.0000003193 53.0
HKD1_k127_1285233_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 598.0
HKD1_k127_1285233_1 Cytochrome c bacterial - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 550.0
HKD1_k127_1285233_10 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 320.0
HKD1_k127_1285233_11 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000001237 258.0
HKD1_k127_1285233_12 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001783 259.0
HKD1_k127_1285233_13 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000001547 180.0
HKD1_k127_1285233_14 Prolyl-tRNA synthetase K03976 - - 0.000000000000000000000000000000000000000000000004068 177.0
HKD1_k127_1285233_15 Putative zinc-finger K03088 - - 0.000000000000000000000000000000000000000003562 162.0
HKD1_k127_1285233_16 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000005975 151.0
HKD1_k127_1285233_17 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000001874 136.0
HKD1_k127_1285233_18 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000143 120.0
HKD1_k127_1285233_19 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000005521 132.0
HKD1_k127_1285233_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 518.0
HKD1_k127_1285233_20 Ribosomal L32p protein family K02911 - - 0.0000000000000000001733 89.0
HKD1_k127_1285233_21 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.00000000000003245 86.0
HKD1_k127_1285233_22 domain, Protein - - - 0.0000000000002317 84.0
HKD1_k127_1285233_23 Putative zinc-finger - - - 0.0000000000002376 73.0
HKD1_k127_1285233_25 YwiC-like protein - - - 0.000000007937 66.0
HKD1_k127_1285233_26 Putative regulatory protein - - - 0.00000001246 60.0
HKD1_k127_1285233_27 Psort location CytoplasmicMembrane, score - - - 0.0001806 52.0
HKD1_k127_1285233_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 471.0
HKD1_k127_1285233_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 432.0
HKD1_k127_1285233_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K02381 GO:0001539,GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0016874,GO:0016877,GO:0016878,GO:0019538,GO:0031974,GO:0032991,GO:0036211,GO:0040011,GO:0042709,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0046777,GO:0048870,GO:0051179,GO:0051674,GO:0070013,GO:0071704,GO:0071973,GO:0097588,GO:1901564,GO:1902494 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 430.0
HKD1_k127_1285233_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 422.0
HKD1_k127_1285233_7 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 399.0
HKD1_k127_1285233_8 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 378.0
HKD1_k127_1285233_9 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 327.0
HKD1_k127_1292164_0 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000586 242.0
HKD1_k127_1292164_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000354 97.0
HKD1_k127_1296205_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 429.0
HKD1_k127_1296205_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000001018 221.0
HKD1_k127_1313_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1184.0
HKD1_k127_1313_1 transport systems, ATPase components K02056 - 3.6.3.17 1.423e-203 647.0
HKD1_k127_1313_10 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 385.0
HKD1_k127_1313_11 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 376.0
HKD1_k127_1313_12 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 379.0
HKD1_k127_1313_13 Dihydroorotate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 365.0
HKD1_k127_1313_14 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 319.0
HKD1_k127_1313_15 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 318.0
HKD1_k127_1313_16 Sodium:solute symporter family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 314.0
HKD1_k127_1313_17 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 298.0
HKD1_k127_1313_18 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 302.0
HKD1_k127_1313_19 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001132 291.0
HKD1_k127_1313_2 Peptidase family M1 domain - - - 3.258e-195 636.0
HKD1_k127_1313_20 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000002114 226.0
HKD1_k127_1313_21 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000002726 109.0
HKD1_k127_1313_22 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000004409 93.0
HKD1_k127_1313_23 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 - - 0.00000000000004175 73.0
HKD1_k127_1313_24 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000001046 78.0
HKD1_k127_1313_25 Trypsin-like peptidase domain K08372 - - 0.000638 51.0
HKD1_k127_1313_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 539.0
HKD1_k127_1313_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 520.0
HKD1_k127_1313_5 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 516.0
HKD1_k127_1313_6 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 488.0
HKD1_k127_1313_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 446.0
HKD1_k127_1313_8 NADH flavin oxidoreductase NADH oxidase K00354 - 1.6.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 432.0
HKD1_k127_1313_9 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 392.0
HKD1_k127_1315_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1336.0
HKD1_k127_1315_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.248e-241 759.0
HKD1_k127_1315_10 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 314.0
HKD1_k127_1315_11 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00018 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.26,1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 300.0
HKD1_k127_1315_12 Transglycosylase SLT domain K08307,K12204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001247 284.0
HKD1_k127_1315_13 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000007775 211.0
HKD1_k127_1315_14 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000007856 166.0
HKD1_k127_1315_15 Phage integrase family - - - 0.000000000002034 72.0
HKD1_k127_1315_16 protein homooligomerization - - - 0.00000000001591 71.0
HKD1_k127_1315_17 TPR repeat - - - 0.0000000001175 72.0
HKD1_k127_1315_18 - - - - 0.000000049 60.0
HKD1_k127_1315_2 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 546.0
HKD1_k127_1315_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 437.0
HKD1_k127_1315_4 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 413.0
HKD1_k127_1315_5 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 400.0
HKD1_k127_1315_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 370.0
HKD1_k127_1315_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 359.0
HKD1_k127_1315_8 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 343.0
HKD1_k127_1315_9 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 333.0
HKD1_k127_1318711_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 1.069e-273 849.0
HKD1_k127_1318711_1 STAS domain - - - 1.693e-217 690.0
HKD1_k127_1318711_10 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000009437 206.0
HKD1_k127_1318711_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000001868 178.0
HKD1_k127_1318711_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000003717 166.0
HKD1_k127_1318711_13 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.00000000000000000000000000000000000000001732 163.0
HKD1_k127_1318711_14 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000004277 154.0
HKD1_k127_1318711_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000002931 153.0
HKD1_k127_1318711_16 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000116 122.0
HKD1_k127_1318711_17 heme a metabolic process K02259 - - 0.00000000000000000000000009948 120.0
HKD1_k127_1318711_18 PFAM Response regulator receiver domain - - - 0.00000000000000000000006577 105.0
HKD1_k127_1318711_19 ADP-ribosylglycohydrolase - - - 0.0000000000008386 76.0
HKD1_k127_1318711_2 PFAM Major Facilitator Superfamily - - - 2.861e-208 658.0
HKD1_k127_1318711_20 ADP-ribosylglycohydrolase - - - 0.00000000001881 66.0
HKD1_k127_1318711_21 HMGL-like - - - 0.00000005854 55.0
HKD1_k127_1318711_22 SPW repeat - - - 0.00002824 51.0
HKD1_k127_1318711_3 carbon starvation protein CstA K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 528.0
HKD1_k127_1318711_4 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 434.0
HKD1_k127_1318711_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 365.0
HKD1_k127_1318711_6 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 319.0
HKD1_k127_1318711_7 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 309.0
HKD1_k127_1318711_8 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005932 276.0
HKD1_k127_1318711_9 ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000009605 221.0
HKD1_k127_1350889_0 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 9.485e-209 655.0
HKD1_k127_1350889_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 5.268e-204 644.0
HKD1_k127_1350889_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000008801 244.0
HKD1_k127_1350889_11 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.00000000000000000000000000000000000000000000000001509 190.0
HKD1_k127_1350889_12 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000003214 172.0
HKD1_k127_1350889_13 Amidohydrolase family - - - 0.000000000000000000000003229 111.0
HKD1_k127_1350889_2 argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 601.0
HKD1_k127_1350889_3 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 557.0
HKD1_k127_1350889_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 529.0
HKD1_k127_1350889_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 420.0
HKD1_k127_1350889_6 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 376.0
HKD1_k127_1350889_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 341.0
HKD1_k127_1350889_8 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 336.0
HKD1_k127_1350889_9 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004811 267.0
HKD1_k127_1364522_1 Protein of unknown function (DUF2847) - - - 0.000000000000002484 78.0
HKD1_k127_1364522_2 protein homooligomerization K07114 - - 0.0000000000001029 73.0
HKD1_k127_1413504_0 PFAM binding-protein-dependent transport systems inner membrane component K10233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 382.0
HKD1_k127_1413504_1 PFAM binding-protein-dependent transport systems inner membrane component K10234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 347.0
HKD1_k127_1413504_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.00000000000000000000003226 100.0
HKD1_k127_1413504_3 RND efflux system, outer membrane lipoprotein, NodT family - - - 0.000001347 53.0
HKD1_k127_1424597_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 412.0
HKD1_k127_1424597_1 Transglycosylase K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 0.0000000000000007121 82.0
HKD1_k127_1424597_2 - - - - 0.000000009225 57.0
HKD1_k127_1442422_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 434.0
HKD1_k127_1442422_1 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000007528 231.0
HKD1_k127_1442422_10 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000007512 61.0
HKD1_k127_1442422_11 PFAM Transposase K07491 - - 0.00000002666 55.0
HKD1_k127_1442422_12 Belongs to the Nudix hydrolase family - - - 0.000001604 55.0
HKD1_k127_1442422_2 TRAP-type C4-dicarboxylate transport system, periplasmic K11688 - - 0.0000000000000000000000000000000000000000000000000000000000001701 224.0
HKD1_k127_1442422_3 - - - - 0.00000000000000000000000000000000000000000000000000075 188.0
HKD1_k127_1442422_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000001493 152.0
HKD1_k127_1442422_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000002843 143.0
HKD1_k127_1442422_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000005536 98.0
HKD1_k127_1442422_7 Belongs to the 'phage' integrase family - - - 0.0000000000000011 83.0
HKD1_k127_1449339_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 517.0
HKD1_k127_1449339_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 406.0
HKD1_k127_1449339_2 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 364.0
HKD1_k127_1449339_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 336.0
HKD1_k127_1449339_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814,K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002434 272.0
HKD1_k127_1449339_5 4Fe-4S dicluster domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007827 269.0
HKD1_k127_1449339_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000001886 106.0
HKD1_k127_145360_0 Belongs to the peptidase M16 family K07263 - - 0.0 1015.0
HKD1_k127_145360_1 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 2.985e-282 880.0
HKD1_k127_145360_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330,K05574 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000000000000000501 188.0
HKD1_k127_145360_11 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000000000000000000000000001522 187.0
HKD1_k127_145360_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000005995 188.0
HKD1_k127_145360_13 - - - - 0.00000000000000000000000000000000000000000000005182 177.0
HKD1_k127_145360_14 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.000000000000000000000000000000000000000000001345 170.0
HKD1_k127_145360_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000001223 160.0
HKD1_k127_145360_16 HEPN domain - - - 0.0000000000000000000000000000000000004707 144.0
HKD1_k127_145360_17 nucleotidyltransferase activity K07075 - - 0.0000000000000000000000000000009116 124.0
HKD1_k127_145360_18 - - - - 0.00000000006122 74.0
HKD1_k127_145360_19 Nucleotidyltransferase domain - - - 0.000002707 61.0
HKD1_k127_145360_2 Type III restriction enzyme, res subunit - - - 4.446e-273 875.0
HKD1_k127_145360_3 PFAM DNA methylase K07319 - 2.1.1.72 5.987e-218 697.0
HKD1_k127_145360_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 601.0
HKD1_k127_145360_5 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 549.0
HKD1_k127_145360_6 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 478.0
HKD1_k127_145360_7 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 444.0
HKD1_k127_145360_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 413.0
HKD1_k127_145360_9 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001846 290.0
HKD1_k127_1457513_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.637e-277 871.0
HKD1_k127_1457513_1 peptidase S16 K01338,K04076,K04770,K16012,K16014 - 3.4.21.53 8.317e-224 705.0
HKD1_k127_1457513_2 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000002215 228.0
HKD1_k127_1457513_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000006508 223.0
HKD1_k127_1457513_4 2Fe-2S -binding domain protein K18029 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016725,GO:0019439,GO:0044237,GO:0044248,GO:0055114 1.17.2.1 0.000000000000000000000000000000000000000000000000000000000002209 213.0
HKD1_k127_1457513_5 adenosine deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000666 200.0
HKD1_k127_1461928_0 Pfam Sulfatase K01130 - 3.1.6.1 0.0 1188.0
HKD1_k127_1461928_1 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 572.0
HKD1_k127_1461928_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 499.0
HKD1_k127_1461928_3 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 350.0
HKD1_k127_1461928_4 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001582 279.0
HKD1_k127_1461928_5 Lipocalin-like domain - - - 0.00000000000000000000000000000000000007517 146.0
HKD1_k127_1461928_6 Histidine kinase K07711 - 2.7.13.3 0.000000000000000000000002671 104.0
HKD1_k127_1461928_7 PFAM Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.00000000000000000000002082 100.0
HKD1_k127_148000_0 tagaturonate epimerase K21619 - 5.1.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 543.0
HKD1_k127_148000_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000001001 241.0
HKD1_k127_148000_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000002404 131.0
HKD1_k127_148000_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000038 135.0
HKD1_k127_1510855_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0 1093.0
HKD1_k127_1510855_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.532e-311 969.0
HKD1_k127_1510855_2 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000325 132.0
HKD1_k127_1510855_3 phosphorelay signal transduction system K07315 - 3.1.3.3 0.00000000000000000000000005263 118.0
HKD1_k127_1510855_4 His Kinase A (phosphoacceptor) domain - - - 0.00002207 51.0
HKD1_k127_1529041_0 Belongs to the DEAD box helicase family K03732,K05592,K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 550.0
HKD1_k127_1529041_1 RNA pseudouridylate synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002356 281.0
HKD1_k127_1529041_2 RNA recognition motif - - - 0.0000000000000000000000000000000000000000222 154.0
HKD1_k127_1529041_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001877 94.0
HKD1_k127_1529041_4 Cold shock K03704 - - 0.000000000000005799 78.0
HKD1_k127_1534742_0 Conserved carboxylase domain K01571,K01960 - 4.1.1.3,6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 569.0
HKD1_k127_1534742_1 coproporphyrinogen oxidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 323.0
HKD1_k127_1534742_2 DinB superfamily - - - 0.0000000000000000000000000003684 120.0
HKD1_k127_1534742_3 glutaconyl-CoA decarboxylase subunit gamma K01615 - 4.1.1.70 0.00000000000001251 84.0
HKD1_k127_1538915_0 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 512.0
HKD1_k127_1538915_1 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000006426 154.0
HKD1_k127_1538915_2 - - - - 0.0000000000001786 78.0
HKD1_k127_1538915_3 Predicted membrane protein (DUF2231) - - - 0.0000000001291 68.0
HKD1_k127_154992_0 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 409.0
HKD1_k127_154992_1 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 317.0
HKD1_k127_154992_2 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000001025 214.0
HKD1_k127_154992_3 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000000000000000000000000000000000000000001296 212.0
HKD1_k127_154992_4 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000009867 146.0
HKD1_k127_154992_5 Helix-hairpin-helix motif - - - 0.0000000000000000000000000000000001846 141.0
HKD1_k127_154992_6 - - - - 0.00000000000000000000000005738 117.0
HKD1_k127_154992_7 mRNA catabolic process - - - 0.000000000000000000002793 99.0
HKD1_k127_154992_8 Transposase and inactivated derivatives K07497 - - 0.000000000000000000005826 93.0
HKD1_k127_1557139_0 PFAM FAD linked oxidase - - - 9.969e-253 784.0
HKD1_k127_1557139_1 Berberine and berberine like - - - 1.119e-245 766.0
HKD1_k127_1557139_2 amine dehydrogenase activity K17285 - - 1.487e-237 741.0
HKD1_k127_1557139_3 ATPase associated with various cellular activities, AAA_5 K02584 - - 4.642e-216 692.0
HKD1_k127_1557139_4 PFAM ThiJ PfpI domain protein K18199 - 4.2.1.103 0.000000000000000000000000000000000000000000000000000000000000000008717 231.0
HKD1_k127_1557139_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004139 236.0
HKD1_k127_1557139_6 Major Facilitator Superfamily - - - 0.00002073 48.0
HKD1_k127_1560928_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.164e-229 728.0
HKD1_k127_1560928_1 O-methyltransferase activity - - - 5.214e-208 671.0
HKD1_k127_1560928_10 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001425 261.0
HKD1_k127_1560928_11 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001762 254.0
HKD1_k127_1560928_12 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000008039 259.0
HKD1_k127_1560928_13 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000005107 233.0
HKD1_k127_1560928_14 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000003721 214.0
HKD1_k127_1560928_15 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000003683 209.0
HKD1_k127_1560928_16 TonB dependent receptor K02014 - - 0.0000000000000000000000000002593 124.0
HKD1_k127_1560928_17 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000002924 79.0
HKD1_k127_1560928_18 - - - - 0.000000001237 66.0
HKD1_k127_1560928_19 Protein of unknown function (DUF1059) - - - 0.00000009069 57.0
HKD1_k127_1560928_2 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 506.0
HKD1_k127_1560928_3 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 510.0
HKD1_k127_1560928_4 PFAM ABC transporter related K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 468.0
HKD1_k127_1560928_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 449.0
HKD1_k127_1560928_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 357.0
HKD1_k127_1560928_7 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 328.0
HKD1_k127_1560928_8 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 324.0
HKD1_k127_1560928_9 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 319.0
HKD1_k127_1575252_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K14189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 361.0
HKD1_k127_1575252_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004379 270.0
HKD1_k127_1575252_2 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.00000000000000000000000000000000000000000000000000000000000002799 235.0
HKD1_k127_1575252_3 OsmC-like protein - - - 0.0000000000000000000000000000000000000001039 156.0
HKD1_k127_1575252_4 - - - - 0.00000000000000000000000000000005362 139.0
HKD1_k127_1575252_5 - - - - 0.00000000000000000002623 94.0
HKD1_k127_1575252_6 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000007992 100.0
HKD1_k127_1575252_7 Uncharacterized protein conserved in archaea (DUF2096) - - - 0.0001577 50.0
HKD1_k127_1575252_8 TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B K03753,K13818 - 2.7.7.77 0.0008042 51.0
HKD1_k127_1576761_0 - - - - 0.0000000000000000000000000000000000000000000000000000001957 205.0
HKD1_k127_1576761_1 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000001979 99.0
HKD1_k127_1576761_2 Major Facilitator Superfamily K08224 - - 0.000000000000000004696 85.0
HKD1_k127_1608433_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000002433 241.0
HKD1_k127_1608433_1 - - - - 0.000000000007268 72.0
HKD1_k127_1608433_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000003635 64.0
HKD1_k127_1608433_3 Acetyltransferase (GNAT) domain - - - 0.000000006912 59.0
HKD1_k127_1631983_0 penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000004706 163.0
HKD1_k127_1631983_1 GHKL domain - - - 0.000000000003041 78.0
HKD1_k127_1649402_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000009022 210.0
HKD1_k127_1661516_0 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.0 1242.0
HKD1_k127_1661516_1 Glycyl-tRNA synthetase beta subunit K01879,K14164 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 2.183e-251 795.0
HKD1_k127_1661516_10 mRNA binding - - - 0.00000000000000000000000000002454 119.0
HKD1_k127_1661516_11 Uncharacterized protein family UPF0054 K07042 - - 0.0000000000000000000000000001822 121.0
HKD1_k127_1661516_12 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000001144 112.0
HKD1_k127_1661516_13 Tetratricopeptide repeat - - - 0.00000000000000000000003503 106.0
HKD1_k127_1661516_14 response regulator K07714 - - 0.000002107 52.0
HKD1_k127_1661516_2 Glycyl-tRNA synthetase, alpha subunit K01878,K14164 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 501.0
HKD1_k127_1661516_3 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 477.0
HKD1_k127_1661516_4 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 438.0
HKD1_k127_1661516_5 KH domain K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 289.0
HKD1_k127_1661516_6 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001316 276.0
HKD1_k127_1661516_7 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000001349 215.0
HKD1_k127_1661516_8 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000002105 183.0
HKD1_k127_1661516_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000002623 186.0
HKD1_k127_1666952_0 PFAM Mu transposase, C-terminal K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 516.0
HKD1_k127_1666952_1 AAA domain K07132 - 3.6.1.3 0.0000000000000000000000000000000000000000000000000001392 197.0
HKD1_k127_1680518_0 YHS domain K17686 - 3.6.3.54 0.0 1067.0
HKD1_k127_1680518_1 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 541.0
HKD1_k127_1680518_10 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000000004889 152.0
HKD1_k127_1680518_11 Cytochrome c K02275 - 1.9.3.1 0.0000000000000000000000000000000000008618 146.0
HKD1_k127_1680518_12 Cytochrome c K02275 - 1.9.3.1 0.00000000000000000000000000000000636 142.0
HKD1_k127_1680518_13 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000005865 114.0
HKD1_k127_1680518_14 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000004366 103.0
HKD1_k127_1680518_15 membrane protein (DUF2078) K08982 - - 0.000000000000518 72.0
HKD1_k127_1680518_16 P-type ATPase K17686 - 3.6.3.54 0.0000000000005997 70.0
HKD1_k127_1680518_2 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 469.0
HKD1_k127_1680518_3 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 453.0
HKD1_k127_1680518_4 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000000000000000006172 207.0
HKD1_k127_1680518_5 HAMP domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001391 218.0
HKD1_k127_1680518_6 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000000000000000004088 196.0
HKD1_k127_1680518_7 Thioredoxin-like K02199,K03671 - - 0.000000000000000000000000000000000000000000000000114 184.0
HKD1_k127_1680518_8 - - - - 0.0000000000000000000000000000000000000000003739 163.0
HKD1_k127_1680518_9 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000244 162.0
HKD1_k127_1690176_0 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 355.0
HKD1_k127_1690176_1 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 296.0
HKD1_k127_1690176_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 256.0
HKD1_k127_1690176_3 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000859 191.0
HKD1_k127_1690176_4 tagaturonate epimerase - - - 0.000000000000000000000000000002858 138.0
HKD1_k127_1690176_5 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000004573 115.0
HKD1_k127_1690176_6 TIGRFAM geranylgeranyl reductase family - - - 0.000000000000000000000004226 109.0
HKD1_k127_1690176_7 Putative transposase - - - 0.0000000000000000000001166 100.0
HKD1_k127_1690176_8 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00004328 51.0
HKD1_k127_1693911_0 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 344.0
HKD1_k127_1693911_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 326.0
HKD1_k127_1693911_2 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 315.0
HKD1_k127_1693911_3 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005379 284.0
HKD1_k127_1693911_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001396 286.0
HKD1_k127_1693911_5 Fructose-1,6-bisphosphate aldolase, class II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000008733 201.0
HKD1_k127_1693911_6 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000003186 171.0
HKD1_k127_1693911_7 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000009522 114.0
HKD1_k127_1693911_8 addiction module antidote protein HigA K21498 - - 0.000000000000001461 82.0
HKD1_k127_1716059_0 conserved protein (DUF2075) K09384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 414.0
HKD1_k127_1716059_1 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002876 248.0
HKD1_k127_1716059_2 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000008104 238.0
HKD1_k127_1716059_3 phosphate-selective porin O and P - - - 0.0000000000000131 86.0
HKD1_k127_178576_0 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 374.0
HKD1_k127_178576_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 344.0
HKD1_k127_1793573_0 GTP-binding protein TypA K06207 - - 9.626e-271 845.0
HKD1_k127_1793573_1 Helix-hairpin-helix containing domain K03581 - 3.1.11.5 6.097e-258 815.0
HKD1_k127_1793573_10 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K07106,K09001 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170,4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 401.0
HKD1_k127_1793573_11 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 328.0
HKD1_k127_1793573_12 SIS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 301.0
HKD1_k127_1793573_13 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 299.0
HKD1_k127_1793573_14 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001906 262.0
HKD1_k127_1793573_15 methyltransferase activity K17462 - - 0.00000000000000000000000000000000000000000000000000000000000000000004965 239.0
HKD1_k127_1793573_16 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.000000000000000000000000000000000000000000000000000000000000000009166 228.0
HKD1_k127_1793573_17 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000005412 231.0
HKD1_k127_1793573_18 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000000000435 120.0
HKD1_k127_1793573_19 haloacid dehalogenase-like hydrolase K06019 - 3.6.1.1 0.00000000000000000000001368 109.0
HKD1_k127_1793573_2 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 586.0
HKD1_k127_1793573_20 - - - - 0.00000000000000000002906 93.0
HKD1_k127_1793573_21 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.000000000000002736 85.0
HKD1_k127_1793573_22 Pilus assembly protein PilX - - - 0.0000000000001119 84.0
HKD1_k127_1793573_23 Type IV Pilus-assembly protein W K02672 - - 0.0000004103 60.0
HKD1_k127_1793573_3 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 562.0
HKD1_k127_1793573_4 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 570.0
HKD1_k127_1793573_5 PFAM Cys Met metabolism PLP-dependent enzyme K01739,K01758 - 2.5.1.48,4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 526.0
HKD1_k127_1793573_6 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 528.0
HKD1_k127_1793573_7 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 449.0
HKD1_k127_1793573_8 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 431.0
HKD1_k127_1793573_9 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 426.0
HKD1_k127_1803860_0 FAD dependent oxidoreductase - - - 3.173e-205 655.0
HKD1_k127_1803860_1 Thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 423.0
HKD1_k127_1803860_2 Cupin 2, conserved barrel domain protein - - - 0.0004827 43.0
HKD1_k127_1812438_0 Belongs to the DegT DnrJ EryC1 family K16016 - 4.2.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 384.0
HKD1_k127_1812438_1 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000000000003507 219.0
HKD1_k127_1812438_2 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000001694 175.0
HKD1_k127_1812438_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000007557 105.0
HKD1_k127_190416_0 ABC transporter transmembrane region K06147,K18889 - - 9.398e-208 663.0
HKD1_k127_190416_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975,K20427 - 2.7.7.27,2.7.7.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 438.0
HKD1_k127_190416_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975,K20427 - 2.7.7.27,2.7.7.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 383.0
HKD1_k127_190416_3 cellular manganese ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 363.0
HKD1_k127_190416_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 355.0
HKD1_k127_190416_5 ABC transporter K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 328.0
HKD1_k127_190416_6 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000001435 181.0
HKD1_k127_190416_7 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000000000001978 149.0
HKD1_k127_1916060_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1147.0
HKD1_k127_1916060_1 PFAM Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 359.0
HKD1_k127_1916060_2 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000148 287.0
HKD1_k127_1916060_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000003947 202.0
HKD1_k127_1916060_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000004083 156.0
HKD1_k127_1920005_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007971 512.0
HKD1_k127_1920005_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 451.0
HKD1_k127_1920005_2 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 375.0
HKD1_k127_1920005_3 Antitoxin component of a toxin-antitoxin (TA) module K19159 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.0000000001987 65.0
HKD1_k127_1920005_4 cytotoxic translational repressor of toxin-antitoxin K06218 - - 0.000002145 53.0
HKD1_k127_1926532_0 2-Keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 327.0
HKD1_k127_1926532_1 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008454 280.0
HKD1_k127_1926532_10 Lipocalin-like domain - - - 0.00000000000000000000000000000009712 135.0
HKD1_k127_1926532_11 Membrane - - - 0.00000000000000000000000005336 115.0
HKD1_k127_1926532_12 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.0000000000000000000000003163 105.0
HKD1_k127_1926532_13 Lipocalin-like domain - - - 0.0000000000000001068 89.0
HKD1_k127_1926532_14 Helix-turn-helix domain K07497 - - 0.00000000000000012 85.0
HKD1_k127_1926532_15 Resolvase, N terminal domain - - - 0.000000000000000416 91.0
HKD1_k127_1926532_16 acetyltransferase K03826 - - 0.0000000000000004211 88.0
HKD1_k127_1926532_19 Resolvase, N terminal domain - - - 0.00000000248 62.0
HKD1_k127_1926532_2 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000007535 224.0
HKD1_k127_1926532_21 Cupin 2 conserved barrel domain protein - - - 0.0000004819 59.0
HKD1_k127_1926532_22 - - - - 0.0000008675 60.0
HKD1_k127_1926532_23 PFAM TPR repeat-containing protein - - - 0.00001661 47.0
HKD1_k127_1926532_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000401 226.0
HKD1_k127_1926532_6 B3 4 domain protein - - - 0.0000000000000000000000000000000000000000000000000008807 192.0
HKD1_k127_1926532_7 SMART Chromosomal replication initiator DnaA domain - - - 0.000000000000000000000000000000000000000002908 164.0
HKD1_k127_1926532_8 Hep Hag repeat protein - - - 0.0000000000000000000000000000000001195 150.0
HKD1_k127_1926532_9 - - - - 0.0000000000000000000000000000000008365 149.0
HKD1_k127_1988920_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.478e-236 748.0
HKD1_k127_1988920_1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 359.0
HKD1_k127_1988920_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000003024 222.0
HKD1_k127_1988920_3 TPM domain K06872 - - 0.00000000000000000000000000000000004727 148.0
HKD1_k127_1988920_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.0000000000000000000000000000002156 126.0
HKD1_k127_1988920_5 nucleotidyltransferase activity - - - 0.00000000000000000000000001285 118.0
HKD1_k127_2017897_0 lipopolysaccharide transport K22110 - - 0.0 1315.0
HKD1_k127_2017897_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.64e-288 899.0
HKD1_k127_2017897_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 334.0
HKD1_k127_2017897_11 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 330.0
HKD1_k127_2017897_12 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 314.0
HKD1_k127_2017897_13 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 309.0
HKD1_k127_2017897_14 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001191 282.0
HKD1_k127_2017897_15 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006318 285.0
HKD1_k127_2017897_16 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009968 277.0
HKD1_k127_2017897_17 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009926 253.0
HKD1_k127_2017897_18 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000002016 241.0
HKD1_k127_2017897_19 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006788 237.0
HKD1_k127_2017897_2 choline dehydrogenase activity - - - 5.796e-253 794.0
HKD1_k127_2017897_20 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000001721 201.0
HKD1_k127_2017897_21 Guanylyl transferase CofC like K09931 - - 0.00000000000000000000000000000000000000000000001386 180.0
HKD1_k127_2017897_22 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000889 174.0
HKD1_k127_2017897_23 - K16937 - 1.8.5.2 0.000000000000000000000000000000000000000001439 162.0
HKD1_k127_2017897_24 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000001314 143.0
HKD1_k127_2017897_25 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000005882 132.0
HKD1_k127_2017897_26 cheY-homologous receiver domain - - - 0.0000000000000926 79.0
HKD1_k127_2017897_27 Tetratricopeptide repeat - - - 0.00000002914 65.0
HKD1_k127_2017897_3 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 5.405e-232 730.0
HKD1_k127_2017897_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 438.0
HKD1_k127_2017897_5 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 411.0
HKD1_k127_2017897_6 with different specificities (related to short-chain alcohol K00034 - 1.1.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 374.0
HKD1_k127_2017897_7 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008093 364.0
HKD1_k127_2017897_8 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 342.0
HKD1_k127_2017897_9 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 336.0
HKD1_k127_2021757_0 unfolded protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 505.0
HKD1_k127_2021757_1 Catalyzes the dehydration of D-mannonate K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 437.0
HKD1_k127_2021757_2 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 433.0
HKD1_k127_2021757_3 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 361.0
HKD1_k127_2021757_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 299.0
HKD1_k127_2021757_5 Carbon-nitrogen hydrolase K01459 - 3.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000255 261.0
HKD1_k127_2021757_6 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000108 246.0
HKD1_k127_2021757_7 CBS domain - - - 0.000000000000000000000000000000000008751 143.0
HKD1_k127_2021757_8 PIN domain - - - 0.00000000000004039 76.0
HKD1_k127_2035488_0 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 499.0
HKD1_k127_2035488_1 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 411.0
HKD1_k127_2035488_10 BON domain K04065 - - 0.000000000000001142 85.0
HKD1_k127_2035488_11 aspartic-type endopeptidase activity - - - 0.000000000000004696 84.0
HKD1_k127_2035488_12 - - - - 0.000000009953 65.0
HKD1_k127_2035488_13 - - - - 0.0000007448 53.0
HKD1_k127_2035488_14 Heavy metal transport detoxification protein K07213 - - 0.0002896 45.0
HKD1_k127_2035488_2 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 393.0
HKD1_k127_2035488_3 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 293.0
HKD1_k127_2035488_4 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006906 290.0
HKD1_k127_2035488_5 Metalloenzyme superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001358 260.0
HKD1_k127_2035488_6 Pterin binding enzyme K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000003343 246.0
HKD1_k127_2035488_7 methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000003141 247.0
HKD1_k127_2035488_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000003059 226.0
HKD1_k127_2035488_9 CS domain K13993 - - 0.000000000000000000000000000000001431 135.0
HKD1_k127_2036739_0 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 309.0
HKD1_k127_2036739_1 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000003694 229.0
HKD1_k127_2045368_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 8.761e-203 658.0
HKD1_k127_2045368_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 426.0
HKD1_k127_2045368_2 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 361.0
HKD1_k127_2064382_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 359.0
HKD1_k127_2064382_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 302.0
HKD1_k127_2072649_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 470.0
HKD1_k127_2072649_1 mannitol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 433.0
HKD1_k127_2072649_10 thiamine-phosphate kinase activity K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000368 160.0
HKD1_k127_2072649_11 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000008088 166.0
HKD1_k127_2072649_12 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000023 150.0
HKD1_k127_2072649_13 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000002925 142.0
HKD1_k127_2072649_14 ketosteroid isomerase - - - 0.00000000000000000000000000000002401 130.0
HKD1_k127_2072649_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000001458 124.0
HKD1_k127_2072649_16 PFAM GGDEF domain containing protein - - - 0.00000000000000000000007357 106.0
HKD1_k127_2072649_17 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.00000000000006562 78.0
HKD1_k127_2072649_18 - - - - 0.0000000004588 66.0
HKD1_k127_2072649_19 Protein of unknown function (DUF1328) - - - 0.000000002223 60.0
HKD1_k127_2072649_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 316.0
HKD1_k127_2072649_20 Protein of unknown function (DUF3096) - - - 0.00000001568 56.0
HKD1_k127_2072649_21 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.0000002842 63.0
HKD1_k127_2072649_22 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0002787 48.0
HKD1_k127_2072649_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002705 274.0
HKD1_k127_2072649_4 carbohydrate transport K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001677 272.0
HKD1_k127_2072649_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000003181 267.0
HKD1_k127_2072649_6 Belongs to the alpha-IPM synthase homocitrate synthase family - - - 0.00000000000000000000000000000000000000000000000000000008177 211.0
HKD1_k127_2072649_7 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.0000000000000000000000000000000000000000000000005883 190.0
HKD1_k127_2072649_8 Phosphoesterase K07095 - - 0.00000000000000000000000000000000000000000000002408 180.0
HKD1_k127_2072649_9 PFAM 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000001212 166.0
HKD1_k127_2074390_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 423.0
HKD1_k127_2074390_1 RmlD substrate binding domain K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 378.0
HKD1_k127_2074390_10 Protein of unknown function (DUF1009) K00748,K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000008793 263.0
HKD1_k127_2074390_11 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006004 254.0
HKD1_k127_2074390_12 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000003484 263.0
HKD1_k127_2074390_13 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000002636 255.0
HKD1_k127_2074390_14 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000001971 228.0
HKD1_k127_2074390_15 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372,K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000002598 218.0
HKD1_k127_2074390_16 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000003323 204.0
HKD1_k127_2074390_17 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000002244 158.0
HKD1_k127_2074390_18 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000002316 161.0
HKD1_k127_2074390_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 379.0
HKD1_k127_2074390_20 FAD dependent oxidoreductase K05898 - 1.3.99.4 0.0000000000000000000000000004787 118.0
HKD1_k127_2074390_21 - - - - 0.0000000000000000849 89.0
HKD1_k127_2074390_22 Glycine-zipper domain - - - 0.0000471 53.0
HKD1_k127_2074390_3 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 368.0
HKD1_k127_2074390_4 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02841,K02843,K02849,K12982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 344.0
HKD1_k127_2074390_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 338.0
HKD1_k127_2074390_6 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 318.0
HKD1_k127_2074390_7 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 294.0
HKD1_k127_2074390_8 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007948 274.0
HKD1_k127_2074390_9 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000002893 273.0
HKD1_k127_2089871_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 373.0
HKD1_k127_2089871_1 PFAM EamA-like transporter family - - - 0.0000004864 61.0
HKD1_k127_2091183_0 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 1.662e-220 689.0
HKD1_k127_2092978_0 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 362.0
HKD1_k127_2092978_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 328.0
HKD1_k127_2094030_0 ABC transporter, solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007869 273.0
HKD1_k127_2094030_1 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000988 135.0
HKD1_k127_2103936_0 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001026 261.0
HKD1_k127_2132203_0 NTPase - - - 0.000000000000000000000000000000000000000002489 162.0
HKD1_k127_2132203_1 alpha beta - - - 0.0000000000000000000000000000000000001163 158.0
HKD1_k127_2132203_2 Nuclease-related domain - - - 0.000000000000000000000001781 109.0
HKD1_k127_2138974_0 Pup-ligase protein K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 528.0
HKD1_k127_2138974_1 Proteasome subunit K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 346.0
HKD1_k127_2138974_2 Proteasome subunit K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 315.0
HKD1_k127_2138974_3 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.00000000000000000000000000000000000000000000000000000000000001069 218.0
HKD1_k127_2141182_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 297.0
HKD1_k127_2141182_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000001963 98.0
HKD1_k127_2141764_0 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 434.0
HKD1_k127_2141764_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 428.0
HKD1_k127_2141764_2 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 385.0
HKD1_k127_2141764_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000001078 231.0
HKD1_k127_2141764_4 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000002684 214.0
HKD1_k127_2141764_5 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000001036 199.0
HKD1_k127_2141764_6 Metal dependent phosphohydrolases with conserved 'HD' motif. K06951 - - 0.0000000000000000000000000000000000000000000000000008403 190.0
HKD1_k127_2141764_7 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00000000000000000000000000000000000000000004768 168.0
HKD1_k127_2141764_8 - - - - 0.0000000000000000000000000007006 115.0
HKD1_k127_2159024_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.273e-203 642.0
HKD1_k127_2159024_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 396.0
HKD1_k127_2159024_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 378.0
HKD1_k127_2159024_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 367.0
HKD1_k127_2159024_4 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 316.0
HKD1_k127_2159024_5 ABC transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002602 264.0
HKD1_k127_216137_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 569.0
HKD1_k127_216137_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 287.0
HKD1_k127_216137_2 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005187 243.0
HKD1_k127_216137_3 PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000011 267.0
HKD1_k127_216137_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000002108 198.0
HKD1_k127_216137_5 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000298 170.0
HKD1_k127_216137_6 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000002499 118.0
HKD1_k127_216137_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0001515 55.0
HKD1_k127_2164258_0 PFAM MULE transposase, conserved domain - - - 0.0000000000000000000000000000000000000000001547 174.0
HKD1_k127_2164258_1 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000004344 159.0
HKD1_k127_2164258_2 PFAM Rhodopirellula transposase family protein - - - 0.00000000000000001128 86.0
HKD1_k127_2164258_3 Rhodopirellula transposase DDE domain - - - 0.0000008603 53.0
HKD1_k127_2173731_0 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000000000000251 211.0
HKD1_k127_2179573_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 461.0
HKD1_k127_2179573_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 329.0
HKD1_k127_2181938_0 PFAM RNA polymerase sigma factor 54, interaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 428.0
HKD1_k127_2181938_1 17 kDa outer membrane surface antigen - - - 0.00000000000000000000000000000000002387 142.0
HKD1_k127_2181938_2 Antibiotic biosynthesis monooxygenase K01056 GO:0003674,GO:0003824 3.1.1.29 0.0000000000000000001272 92.0
HKD1_k127_2181938_3 EF hand - - - 0.0001678 53.0
HKD1_k127_2188386_0 glycogen phosphorylase activity K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 364.0
HKD1_k127_2188386_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006979 262.0
HKD1_k127_2188386_2 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001144 256.0
HKD1_k127_2188386_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000003197 123.0
HKD1_k127_2194479_0 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 577.0
HKD1_k127_2194479_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02407,K02492,K10714 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 454.0
HKD1_k127_2194479_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 318.0
HKD1_k127_2194479_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000089 244.0
HKD1_k127_2194479_4 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000001026 226.0
HKD1_k127_2194479_5 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000004738 176.0
HKD1_k127_2194479_6 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000151 114.0
HKD1_k127_2198757_0 PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 488.0
HKD1_k127_2198757_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 356.0
HKD1_k127_2198757_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 325.0
HKD1_k127_2198757_3 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000005329 198.0
HKD1_k127_2198757_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000009659 161.0
HKD1_k127_2198757_5 glutaconyl-CoA decarboxylase subunit gamma K01615 - 4.1.1.70 0.00000000000000001032 88.0
HKD1_k127_2214435_0 KR domain K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000001169 211.0
HKD1_k127_2214435_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000005424 203.0
HKD1_k127_2214435_2 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000006184 184.0
HKD1_k127_2214435_3 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000001751 152.0
HKD1_k127_2214435_4 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000005159 147.0
HKD1_k127_2214435_5 EamA-like transporter family - - - 0.00000000000000002324 93.0
HKD1_k127_2214435_6 Outer membrane lipoprotein - - - 0.00000000000000004114 93.0
HKD1_k127_2217854_0 Domain of unknown function (DUF4440) - - - 0.00000000003358 73.0
HKD1_k127_2238201_0 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 387.0
HKD1_k127_2238201_1 Transporter anaerobic C4-dicarboxylate uptake C K03326 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 351.0
HKD1_k127_2238201_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000001588 149.0
HKD1_k127_2238201_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 0.000000000000000000000000000001019 126.0
HKD1_k127_2262436_0 Sulfatase K01130 - 3.1.6.1 0.0 1363.0
HKD1_k127_2262436_1 Sulfatase K01130 - 3.1.6.1 0.0 1343.0
HKD1_k127_2262436_10 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 392.0
HKD1_k127_2262436_11 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 374.0
HKD1_k127_2262436_12 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 359.0
HKD1_k127_2262436_13 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 353.0
HKD1_k127_2262436_14 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 349.0
HKD1_k127_2262436_15 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 307.0
HKD1_k127_2262436_16 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 303.0
HKD1_k127_2262436_17 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 291.0
HKD1_k127_2262436_18 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 288.0
HKD1_k127_2262436_19 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000007116 237.0
HKD1_k127_2262436_2 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 573.0
HKD1_k127_2262436_20 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000007853 229.0
HKD1_k127_2262436_21 Metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000126 217.0
HKD1_k127_2262436_22 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000001327 223.0
HKD1_k127_2262436_23 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000001645 183.0
HKD1_k127_2262436_24 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000001391 169.0
HKD1_k127_2262436_25 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000002209 163.0
HKD1_k127_2262436_26 transcriptional K03710 - - 0.00000000000000000000000000000000000000003218 161.0
HKD1_k127_2262436_27 Protein of unknown function (DUF1349) K09702 - - 0.000000000000000000000000000000000000001017 154.0
HKD1_k127_2262436_28 Protein of unknown function (DUF971) K03593 - - 0.000000000000000000000000000000005694 133.0
HKD1_k127_2262436_29 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000001541 138.0
HKD1_k127_2262436_3 Belongs to the 3-oxoacid CoA-transferase family K01026 - 2.8.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 556.0
HKD1_k127_2262436_30 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000003559 109.0
HKD1_k127_2262436_31 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000000000000000000518 101.0
HKD1_k127_2262436_32 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.00000000000000000001278 98.0
HKD1_k127_2262436_33 photosystem II stabilization K02237,K02238 - - 0.00000003453 64.0
HKD1_k127_2262436_34 Ribbon-helix-helix protein, copG family - - - 0.0000001917 56.0
HKD1_k127_2262436_35 peptidyl-tyrosine sulfation - - - 0.00003995 50.0
HKD1_k127_2262436_37 Enoyl-(Acyl carrier protein) reductase - - - 0.0001028 45.0
HKD1_k127_2262436_4 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 507.0
HKD1_k127_2262436_5 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 490.0
HKD1_k127_2262436_6 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 459.0
HKD1_k127_2262436_7 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 411.0
HKD1_k127_2262436_8 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 397.0
HKD1_k127_2262436_9 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 407.0
HKD1_k127_2265361_0 SWIM zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 517.0
HKD1_k127_2265361_1 type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 345.0
HKD1_k127_2265361_2 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002888 282.0
HKD1_k127_2265361_3 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004346 253.0
HKD1_k127_2265361_4 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000003194 200.0
HKD1_k127_2265361_5 - - - - 0.0000000000000000000000000000005591 123.0
HKD1_k127_2265361_6 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000003684 115.0
HKD1_k127_2265361_7 Protein of unknown function (DUF433) - - - 0.00000000000000005312 83.0
HKD1_k127_2265361_8 - - - - 0.000000000003517 69.0
HKD1_k127_2265361_9 - - - - 0.000000008634 58.0
HKD1_k127_2272196_0 COG2801 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 446.0
HKD1_k127_2272196_1 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000009545 250.0
HKD1_k127_2272196_2 Tannase and feruloyl esterase - - - 0.000000000001289 81.0
HKD1_k127_2278373_0 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.0 1107.0
HKD1_k127_2278373_1 oxidoreductase K00311,K00313 - 1.5.5.1 4.457e-295 919.0
HKD1_k127_2278373_2 electron transfer activity K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 415.0
HKD1_k127_2278373_3 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000002724 240.0
HKD1_k127_2278373_4 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.00000000000000007291 82.0
HKD1_k127_2306878_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1219.0
HKD1_k127_2306878_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008678 466.0
HKD1_k127_2306878_2 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 444.0
HKD1_k127_2306878_3 SMART ATPase, AAA type, core K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 375.0
HKD1_k127_2306878_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 360.0
HKD1_k127_2306878_5 ABC-type sugar K02025,K10237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 355.0
HKD1_k127_2306878_6 daunorubicin resistance ABC transporter membrane protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 343.0
HKD1_k127_2306878_7 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 324.0
HKD1_k127_2306878_8 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000001625 144.0
HKD1_k127_2313442_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 399.0
HKD1_k127_2313442_1 - - - - 0.000000000000000000000000000000000000000000000000000006179 199.0
HKD1_k127_2316578_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1362.0
HKD1_k127_2316578_1 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 484.0
HKD1_k127_2316578_10 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.0001781 50.0
HKD1_k127_2316578_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 406.0
HKD1_k127_2316578_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 365.0
HKD1_k127_2316578_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 343.0
HKD1_k127_2316578_5 'glutamate synthase K00123,K00317,K00528,K09835 - 1.17.1.9,1.18.1.2,1.19.1.1,1.5.8.1,1.5.8.2,5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 342.0
HKD1_k127_2316578_6 OmpA family K03640 - - 0.000000000000000000000000000000000001295 149.0
HKD1_k127_2316578_7 PFAM Peptidase S24 S26A S26B, conserved region K03100 - 3.4.21.89 0.00000000000000000000000000000005039 133.0
HKD1_k127_2316578_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000004503 95.0
HKD1_k127_2316578_9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669 - - 0.00000000000000000121 91.0
HKD1_k127_2326656_0 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 449.0
HKD1_k127_2326656_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 391.0
HKD1_k127_2326656_2 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 397.0
HKD1_k127_2326656_3 homoserine dehydrogenase - - - 0.00000000000000000000000000000000000000000000002403 173.0
HKD1_k127_2327997_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1315.0
HKD1_k127_2336661_0 Belongs to the glycosyl hydrolase 43 family K01198 - 3.2.1.37 8.935e-229 711.0
HKD1_k127_2336661_1 PFAM Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 550.0
HKD1_k127_2338339_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000001468 261.0
HKD1_k127_2338339_1 MacB-like periplasmic core domain K02004,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000112 210.0
HKD1_k127_2338339_2 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000001409 159.0
HKD1_k127_2338339_3 PFAM LmbE family protein - - - 0.0000000000000000000000000002574 125.0
HKD1_k127_2338339_4 Glycosyl transferase, family 2 - - - 0.000000000000000000000007601 102.0
HKD1_k127_2344845_0 ABC transporter transmembrane region K06147,K18893 - - 6.749e-276 861.0
HKD1_k127_2344845_1 regulation of DNA-templated transcription, elongation - - - 7.824e-273 864.0
HKD1_k127_2344845_2 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 367.0
HKD1_k127_2344845_3 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 376.0
HKD1_k127_2344845_4 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 317.0
HKD1_k127_2344845_5 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002904 266.0
HKD1_k127_2345601_0 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 423.0
HKD1_k127_2345601_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 369.0
HKD1_k127_2345601_10 PFAM Transposase IS66 family K07484 - - 0.00000000000001223 76.0
HKD1_k127_2345601_11 PFAM Helix-turn-helix - - - 0.00000000003254 69.0
HKD1_k127_2345601_12 - - - - 0.00000002687 58.0
HKD1_k127_2345601_13 iron dependent repressor - - - 0.00003641 51.0
HKD1_k127_2345601_3 protein, Hemolysin III K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 283.0
HKD1_k127_2345601_4 Penicillin-insensitive murein endopeptidase K07261 - - 0.00000000000000000000000000000000000000000000000000000000000000000001085 247.0
HKD1_k127_2345601_5 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000005709 188.0
HKD1_k127_2345601_6 response regulator K02481,K07713 - - 0.000000000000000000000000000000000000000000003184 171.0
HKD1_k127_2345601_7 ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000266 154.0
HKD1_k127_2345601_8 methylamine metabolic process K15977 - - 0.0000000000000000000000000000003015 136.0
HKD1_k127_2345601_9 Diguanylate cyclase - - - 0.0000000000000000008602 93.0
HKD1_k127_2365460_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 4.435e-299 944.0
HKD1_k127_2365460_1 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 1.661e-277 861.0
HKD1_k127_2365460_2 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 7.154e-248 781.0
HKD1_k127_2365460_3 glycogen (starch) synthase activity K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 476.0
HKD1_k127_2370186_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02049,K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 462.0
HKD1_k127_2370186_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 417.0
HKD1_k127_2370186_10 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000001916 229.0
HKD1_k127_2370186_11 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000002008 226.0
HKD1_k127_2370186_12 6-phosphogluconate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000008204 199.0
HKD1_k127_2370186_13 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000003755 188.0
HKD1_k127_2370186_14 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000002608 174.0
HKD1_k127_2370186_15 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000019 145.0
HKD1_k127_2370186_16 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000003313 152.0
HKD1_k127_2370186_17 - - - - 0.000000000000000000000000084 114.0
HKD1_k127_2370186_18 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000001879 113.0
HKD1_k127_2370186_19 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000000209 106.0
HKD1_k127_2370186_2 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 411.0
HKD1_k127_2370186_20 Regulatory protein, FmdB family - - - 0.00000000000000007085 84.0
HKD1_k127_2370186_21 Peptidase family S58 K01266 - 3.4.11.19 0.000000000009349 72.0
HKD1_k127_2370186_22 - - - - 0.0000000002601 70.0
HKD1_k127_2370186_23 - - - - 0.000000001507 63.0
HKD1_k127_2370186_25 - - - - 0.0002575 49.0
HKD1_k127_2370186_3 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 404.0
HKD1_k127_2370186_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 364.0
HKD1_k127_2370186_5 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 387.0
HKD1_k127_2370186_6 Mandelate racemase muconate lactonizing enzyme, N-terminal domain K01683,K01684 - 4.2.1.5,4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 346.0
HKD1_k127_2370186_7 peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 346.0
HKD1_k127_2370186_8 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004728 274.0
HKD1_k127_2370186_9 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002515 256.0
HKD1_k127_2384524_0 N-acetyl-gamma-glutamyl-phosphate reductase activity K00145,K05829 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 455.0
HKD1_k127_2384524_1 PFAM ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp K05827 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 428.0
HKD1_k127_2384524_2 Belongs to the acetylglutamate kinase family. LysZ subfamily K05828 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 334.0
HKD1_k127_2384524_3 acetylornithine and succinylornithine aminotransferase K00821,K05830 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 304.0
HKD1_k127_2384524_4 hydrolase (HAD superfamily) K07025 - - 0.000000000000000000000000000000000002226 148.0
HKD1_k127_2384524_5 TIGRFAM lysine biosynthesis protein LysW K05826 - - 0.00000000000002253 74.0
HKD1_k127_23883_0 Iron-sulfur cluster-binding domain K06871 - - 1.229e-231 723.0
HKD1_k127_23883_1 arylsulfatase activity K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000002083 192.0
HKD1_k127_2411517_0 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 319.0
HKD1_k127_2416037_0 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 361.0
HKD1_k127_2416037_1 PFAM 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 305.0
HKD1_k127_2416037_2 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002204 298.0
HKD1_k127_2416037_3 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.000005019 51.0
HKD1_k127_2416037_4 Beta-lactamase superfamily domain - - - 0.000958 45.0
HKD1_k127_2419783_0 PFAM Peptidase M11 gametolysin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 428.0
HKD1_k127_2429666_0 4Fe-4S binding domain K02572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 519.0
HKD1_k127_2429666_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 311.0
HKD1_k127_2429666_2 ACT domain K09707 - - 0.0000000000000000000000000001902 120.0
HKD1_k127_2429666_3 Aldo/keto reductase family K07079 - - 0.0000000000000000000001619 104.0
HKD1_k127_2429666_4 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.00000002622 60.0
HKD1_k127_2429666_5 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.00002409 48.0
HKD1_k127_2433873_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.065e-317 979.0
HKD1_k127_2433873_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 1.483e-197 625.0
HKD1_k127_2433873_10 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000003366 177.0
HKD1_k127_2433873_11 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000006701 184.0
HKD1_k127_2433873_12 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000000002862 152.0
HKD1_k127_2433873_13 PFAM transport-associated - - - 0.00000000000000000000000000000004151 142.0
HKD1_k127_2433873_14 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997,K01207 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7,3.2.1.52 0.00000000000000000000000001117 116.0
HKD1_k127_2433873_15 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000001582 115.0
HKD1_k127_2433873_16 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000004227 97.0
HKD1_k127_2433873_17 Trm112p-like protein K09791 - - 0.000000000000000006561 85.0
HKD1_k127_2433873_2 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 536.0
HKD1_k127_2433873_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 539.0
HKD1_k127_2433873_4 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 396.0
HKD1_k127_2433873_5 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 388.0
HKD1_k127_2433873_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 302.0
HKD1_k127_2433873_7 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000009865 271.0
HKD1_k127_2433873_8 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000003145 234.0
HKD1_k127_2433873_9 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000004098 198.0
HKD1_k127_2436829_0 Hydantoinase/oxoprolinase - - - 5.183e-261 822.0
HKD1_k127_2436829_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 548.0
HKD1_k127_2436829_10 Transketolase, central region K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004314 265.0
HKD1_k127_2436829_11 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000003363 248.0
HKD1_k127_2436829_12 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000006337 243.0
HKD1_k127_2436829_13 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000009267 216.0
HKD1_k127_2436829_14 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000000000000000000000000000000448 194.0
HKD1_k127_2436829_15 KR domain - - - 0.00000000000000000000000000000000000000000000002644 182.0
HKD1_k127_2436829_16 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000000000006161 160.0
HKD1_k127_2436829_17 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000001522 76.0
HKD1_k127_2436829_18 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000001773 74.0
HKD1_k127_2436829_19 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000002474 62.0
HKD1_k127_2436829_2 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 524.0
HKD1_k127_2436829_3 CoA-transferase family III K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 506.0
HKD1_k127_2436829_4 C4-dicarboxylate transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 473.0
HKD1_k127_2436829_5 homoserine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 416.0
HKD1_k127_2436829_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 390.0
HKD1_k127_2436829_7 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 334.0
HKD1_k127_2436829_8 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 307.0
HKD1_k127_2436829_9 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005433 282.0
HKD1_k127_2457394_0 TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1189.0
HKD1_k127_2457394_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 449.0
HKD1_k127_2457394_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000009066 194.0
HKD1_k127_2471395_0 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 440.0
HKD1_k127_2471395_1 KR domain - - - 0.0000000000000000000000000000000006925 134.0
HKD1_k127_2474229_0 COG3209 Rhs family protein - - - 0.000000000000000000000001496 118.0
HKD1_k127_2474229_1 response regulator K02481 - - 0.0000001555 59.0
HKD1_k127_2494235_0 Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 360.0
HKD1_k127_2494235_1 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 339.0
HKD1_k127_2494235_2 transposase activity - - - 0.000000000000000000000000000000000002576 140.0
HKD1_k127_2495449_0 Phosphotransferase system HPr (HPr) family protein K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0 1024.0
HKD1_k127_2495449_1 Phosphotransferase System K02749,K02750,K02778,K02779,K02790,K02791,K02803,K02804 - 2.7.1.193,2.7.1.199,2.7.1.208 2.585e-232 734.0
HKD1_k127_2495449_10 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 535.0
HKD1_k127_2495449_11 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 426.0
HKD1_k127_2495449_12 SMART Chromosomal replication initiator DnaA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 397.0
HKD1_k127_2495449_13 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 358.0
HKD1_k127_2495449_14 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 334.0
HKD1_k127_2495449_15 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002021 284.0
HKD1_k127_2495449_16 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000003867 264.0
HKD1_k127_2495449_17 proteolysis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005748 244.0
HKD1_k127_2495449_18 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000006321 227.0
HKD1_k127_2495449_19 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000005634 226.0
HKD1_k127_2495449_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 3.416e-222 701.0
HKD1_k127_2495449_20 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000003298 222.0
HKD1_k127_2495449_21 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000002481 221.0
HKD1_k127_2495449_22 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.0000000000000000000000000000000000000000000000000000006291 204.0
HKD1_k127_2495449_23 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000000000000000000001532 199.0
HKD1_k127_2495449_24 - K00003,K00058,K01754,K04517,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,1.3.1.12,4.3.1.19 0.0000000000000000000000000000000000000000000116 169.0
HKD1_k127_2495449_25 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000001861 169.0
HKD1_k127_2495449_26 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000005795 155.0
HKD1_k127_2495449_27 transcriptional K03710 - - 0.000000000000000000000000000000001692 138.0
HKD1_k127_2495449_28 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000004056 131.0
HKD1_k127_2495449_29 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000000004195 129.0
HKD1_k127_2495449_3 ATP-dependent DNA helicase K03657 - 3.6.4.12 7.292e-217 698.0
HKD1_k127_2495449_30 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000003724 111.0
HKD1_k127_2495449_31 PFAM AsmA family protein K07289 - - 0.0000000000000000000000001051 124.0
HKD1_k127_2495449_33 PFAM Methyltransferase type - - - 0.00000000000000000001169 102.0
HKD1_k127_2495449_35 Methyltransferase domain - - - 0.00000000000001322 82.0
HKD1_k127_2495449_36 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000003129 67.0
HKD1_k127_2495449_37 homoserine transmembrane transporter activity K06600,K06895 - - 0.000000001158 67.0
HKD1_k127_2495449_4 cadmium-exporting ATPase K01534 - 3.6.3.3,3.6.3.5 1.073e-216 692.0
HKD1_k127_2495449_5 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 9.841e-212 676.0
HKD1_k127_2495449_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 1.12e-202 640.0
HKD1_k127_2495449_7 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 617.0
HKD1_k127_2495449_8 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 588.0
HKD1_k127_2495449_9 PFAM Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 580.0
HKD1_k127_249985_0 Threonine synthase K01733 - 4.2.3.1 6.039e-292 906.0
HKD1_k127_249985_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 439.0
HKD1_k127_249985_10 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000198 250.0
HKD1_k127_249985_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000002544 240.0
HKD1_k127_249985_12 (Rhomboid) family - - - 0.0000000000000000000000000000000000000000000000000000000000000004722 241.0
HKD1_k127_249985_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000006655 186.0
HKD1_k127_249985_14 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000009888 142.0
HKD1_k127_249985_15 Psort location Cytoplasmic, score - - - 0.0000000000000000000006257 108.0
HKD1_k127_249985_16 Domain of unknown function (DUF1844) - - - 0.000000000000000007272 87.0
HKD1_k127_249985_17 peptidyl-tyrosine sulfation K00525,K01768 - 1.17.4.1,4.6.1.1 0.00000003341 65.0
HKD1_k127_249985_2 PFAM SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 413.0
HKD1_k127_249985_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 409.0
HKD1_k127_249985_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 367.0
HKD1_k127_249985_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 335.0
HKD1_k127_249985_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 321.0
HKD1_k127_249985_7 Nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000091 282.0
HKD1_k127_249985_8 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001204 274.0
HKD1_k127_249985_9 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002507 254.0
HKD1_k127_2506219_0 PFAM 4Fe-4S K00184,K21308 - - 0.0 1179.0
HKD1_k127_2506219_1 aldehyde ferredoxin oxidoreductase activity K03738,K11389 - 1.2.7.5,1.2.7.6 3.523e-318 987.0
HKD1_k127_2506219_10 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 355.0
HKD1_k127_2506219_11 ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 346.0
HKD1_k127_2506219_12 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 332.0
HKD1_k127_2506219_13 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 322.0
HKD1_k127_2506219_14 PFAM aminotransferase, class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 312.0
HKD1_k127_2506219_15 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 303.0
HKD1_k127_2506219_16 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003171 286.0
HKD1_k127_2506219_17 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001984 282.0
HKD1_k127_2506219_18 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006222 237.0
HKD1_k127_2506219_19 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000002898 246.0
HKD1_k127_2506219_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 5.941e-295 925.0
HKD1_k127_2506219_20 Acetamidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000003962 231.0
HKD1_k127_2506219_21 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000009072 224.0
HKD1_k127_2506219_22 spore germination - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000001258 220.0
HKD1_k127_2506219_23 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.00000000000000000000000000000000000000000000000000000001905 205.0
HKD1_k127_2506219_24 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.0000000000000000000000000001674 119.0
HKD1_k127_2506219_25 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000002798 91.0
HKD1_k127_2506219_26 GIY-YIG catalytic domain protein K07461 - - 0.00000000000000001635 85.0
HKD1_k127_2506219_27 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000005571 81.0
HKD1_k127_2506219_28 - - - - 0.00000000000008506 77.0
HKD1_k127_2506219_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 7.771e-269 845.0
HKD1_k127_2506219_4 TIGRFAM glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 3.106e-250 790.0
HKD1_k127_2506219_5 Polysulphide reductase, NrfD K00185 - - 6.686e-218 685.0
HKD1_k127_2506219_6 (ABC) transporter K15738 - - 1.079e-209 672.0
HKD1_k127_2506219_7 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 408.0
HKD1_k127_2506219_8 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 381.0
HKD1_k127_2506219_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 366.0
HKD1_k127_2508837_0 sptr a7nhu5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 419.0
HKD1_k127_2508837_1 COG4422 Bacteriophage protein gp37 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003461 262.0
HKD1_k127_2509309_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 5.68e-286 906.0
HKD1_k127_2509309_1 TRAP transporter, 4TM 12TM fusion protein - - - 1.019e-279 874.0
HKD1_k127_2509309_2 Ammonium Transporter Family K03320 - - 1.707e-200 636.0
HKD1_k127_2509309_3 General secretory system II, protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 387.0
HKD1_k127_2509309_4 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000001213 250.0
HKD1_k127_2509309_5 Domain of unknown function (DUF1850) - - - 0.0000000000000000000000004633 105.0
HKD1_k127_2516533_0 Cysteine-rich domain K11473,K21834 - - 1.95e-247 779.0
HKD1_k127_2516533_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 374.0
HKD1_k127_2516533_2 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 336.0
HKD1_k127_2516533_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 305.0
HKD1_k127_2516533_4 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000811 282.0
HKD1_k127_2516533_5 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004931 279.0
HKD1_k127_2516533_6 PFAM short chain dehydrogenase K00046,K00065,K18009 - 1.1.1.127,1.1.1.304,1.1.1.69,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000001722 212.0
HKD1_k127_2516533_7 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000003889 201.0
HKD1_k127_2516533_8 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.00000000000000000000000000000000872 132.0
HKD1_k127_2528404_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 2.149e-214 670.0
HKD1_k127_2528404_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 601.0
HKD1_k127_2528404_10 Permease YjgP YjgQ family protein K07091,K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001376 276.0
HKD1_k127_2528404_11 transferase activity, transferring glycosyl groups K02844 - - 0.000000000000000000000000000000000000000000000000000000000008345 222.0
HKD1_k127_2528404_12 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000000000000000000002465 199.0
HKD1_k127_2528404_13 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000919 153.0
HKD1_k127_2528404_14 methyltransferase - - - 0.000000000000000000000001879 113.0
HKD1_k127_2528404_16 Binding-protein-dependent transport system inner membrane component K02025,K02026,K17239,K17331 - - 0.0003855 43.0
HKD1_k127_2528404_2 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 622.0
HKD1_k127_2528404_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 576.0
HKD1_k127_2528404_4 PFAM Extracellular ligand-binding receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 508.0
HKD1_k127_2528404_5 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 407.0
HKD1_k127_2528404_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 353.0
HKD1_k127_2528404_7 Permease YjgP YjgQ K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 322.0
HKD1_k127_2528404_8 COG0410 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001941 286.0
HKD1_k127_2528404_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009199 285.0
HKD1_k127_2548323_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 9.415e-198 625.0
HKD1_k127_2548323_1 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 368.0
HKD1_k127_2548323_2 Allophanate hydrolase subunit 1 K06351 - - 0.00002439 47.0
HKD1_k127_2551080_0 PFAM alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 2.204e-251 786.0
HKD1_k127_2551080_1 PFAM Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 553.0
HKD1_k127_2551080_10 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 325.0
HKD1_k127_2551080_11 binding-protein-dependent transport systems inner membrane component K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009893 252.0
HKD1_k127_2551080_12 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004541 251.0
HKD1_k127_2551080_13 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000001681 227.0
HKD1_k127_2551080_14 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000006933 224.0
HKD1_k127_2551080_15 Belongs to the UPF0403 family - - - 0.0000000000000000000000000000000000000000000000000000000008036 205.0
HKD1_k127_2551080_16 Cytochrome c mono- and diheme variants - - - 0.000000000000000000000000000000000000000000000000000000002051 205.0
HKD1_k127_2551080_17 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000008892 173.0
HKD1_k127_2551080_18 Predicted permease K07089 - - 0.000000000000000000000000000000000000021 148.0
HKD1_k127_2551080_19 GntR family - - - 0.0000000000000000000000000000000000005362 152.0
HKD1_k127_2551080_2 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 550.0
HKD1_k127_2551080_20 haloacid dehalogenase-like hydrolase - - - 0.00000002056 62.0
HKD1_k127_2551080_21 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 0.0000002606 56.0
HKD1_k127_2551080_3 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 495.0
HKD1_k127_2551080_4 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 492.0
HKD1_k127_2551080_5 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 484.0
HKD1_k127_2551080_6 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 487.0
HKD1_k127_2551080_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 456.0
HKD1_k127_2551080_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 384.0
HKD1_k127_2551080_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 382.0
HKD1_k127_2561029_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 306.0
HKD1_k127_2561029_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000149 289.0
HKD1_k127_2562968_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 9.658e-289 897.0
HKD1_k127_2562968_1 SMART Nucleotide binding protein, PINc K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 303.0
HKD1_k127_2579183_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 8.453e-275 862.0
HKD1_k127_258204_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833,K03851,K12256,K15372 - 2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 435.0
HKD1_k127_258204_1 ABC-type polar amino acid transport system ATPase component K09972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 329.0
HKD1_k127_258204_10 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000008723 59.0
HKD1_k127_258204_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 314.0
HKD1_k127_258204_3 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009921 304.0
HKD1_k127_258204_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001895 251.0
HKD1_k127_258204_5 belongs to the bacterial solute-binding protein 3 family K02030 - - 0.00000000000000000000000000000000000000000000001229 182.0
HKD1_k127_258204_6 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000002459 178.0
HKD1_k127_258204_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000007104 169.0
HKD1_k127_258204_8 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000001761 158.0
HKD1_k127_258204_9 FCD - - - 0.0000000000000000000000000000154 129.0
HKD1_k127_2601161_0 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 338.0
HKD1_k127_2601161_1 Aminotransferase, class I - - - 0.000000000000000000000000000000000006431 143.0
HKD1_k127_2601161_2 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00059 - 1.1.1.100 0.0000000000000000000000000001121 119.0
HKD1_k127_2611357_0 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 387.0
HKD1_k127_2611357_1 membrane protein of uknown function UCP014873 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001524 233.0
HKD1_k127_2611357_2 Protein of unknown function (DUF1269) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003278 232.0
HKD1_k127_2611357_3 OmpA family K03640 - - 0.000000000000000000000000000000000000000004523 162.0
HKD1_k127_2611357_4 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000000000001183 131.0
HKD1_k127_2611357_5 PFAM transport-associated K04065 - - 0.000000001118 66.0
HKD1_k127_2618170_0 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000001015 213.0
HKD1_k127_2618170_1 - - - - 0.00000000000000000000000000000000000000000000000001421 185.0
HKD1_k127_2618170_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000005109 149.0
HKD1_k127_2618170_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000006451 144.0
HKD1_k127_2618170_4 YCII-related domain K09780 - - 0.000000000000000000000000000000000008527 138.0
HKD1_k127_2635294_0 DNA polymerase X family K02347,K04477 - - 5.338e-225 711.0
HKD1_k127_2635294_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 569.0
HKD1_k127_2635294_10 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000004981 230.0
HKD1_k127_2635294_11 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000004374 191.0
HKD1_k127_2635294_12 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.00000000000000000000000000000000000000002284 161.0
HKD1_k127_2635294_13 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000001586 148.0
HKD1_k127_2635294_14 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.00000000000000000000000000000000000002069 152.0
HKD1_k127_2635294_15 Glycoprotease family - - - 0.000000000000000000000000000000000005978 145.0
HKD1_k127_2635294_16 PIN domain - - - 0.0000000000000000000000000000000001337 137.0
HKD1_k127_2635294_17 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000007104 122.0
HKD1_k127_2635294_18 positive regulation of growth - - - 0.00000000000000000005144 93.0
HKD1_k127_2635294_19 Protein of unknown function (DUF721) - - - 0.000000000001737 74.0
HKD1_k127_2635294_2 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 552.0
HKD1_k127_2635294_20 DUF72 domain containing protein - - - 0.0004207 45.0
HKD1_k127_2635294_3 histidine kinase, HAMP K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 567.0
HKD1_k127_2635294_4 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 547.0
HKD1_k127_2635294_5 Radical SAM superfamily K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 372.0
HKD1_k127_2635294_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K16363 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 369.0
HKD1_k127_2635294_7 O-methyltransferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 325.0
HKD1_k127_2635294_8 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 320.0
HKD1_k127_2635294_9 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000008584 230.0
HKD1_k127_2639733_0 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 400.0
HKD1_k127_2639733_1 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 398.0
HKD1_k127_2639733_2 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000000118 205.0
HKD1_k127_2639733_3 PFAM Uncharacterised BCR, COG1937 K21600 - - 0.0000000000000000000001108 103.0
HKD1_k127_2639733_4 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000002035 94.0
HKD1_k127_2639733_5 E1-E2 ATPase K01534 - 3.6.3.3,3.6.3.5 0.000000000009296 70.0
HKD1_k127_2639733_6 Phage integrase family - - - 0.000000001268 64.0
HKD1_k127_2658226_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009362 526.0
HKD1_k127_2658226_1 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001232 266.0
HKD1_k127_2658226_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001255 274.0
HKD1_k127_2702714_0 transmembrane transporter activity K03296 - - 0.0 1039.0
HKD1_k127_2702714_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 352.0
HKD1_k127_2702714_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001232 252.0
HKD1_k127_2702714_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000001184 258.0
HKD1_k127_2702714_4 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000009907 120.0
HKD1_k127_2702714_5 PFAM response regulator receiver - - - 0.000000000000000000000001844 110.0
HKD1_k127_2702714_6 Tim44 K15539 - - 0.00000000000002013 76.0
HKD1_k127_2702714_7 PFAM Outer membrane efflux protein - - - 0.0000000000001542 83.0
HKD1_k127_2702714_8 FOG TPR repeat - - - 0.000000004782 63.0
HKD1_k127_2722589_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 455.0
HKD1_k127_2722589_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000008187 244.0
HKD1_k127_2722589_2 PFAM alpha beta hydrolase - - - 0.0000000000000006805 82.0
HKD1_k127_2722589_3 Belongs to the thioredoxin family K03671 - - 0.0000003332 62.0
HKD1_k127_2746764_0 regulation of DNA-templated transcription, elongation - - - 3.781e-194 635.0
HKD1_k127_2746764_1 Phospholipase D. Active site motifs. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001594 281.0
HKD1_k127_2746764_2 - - - - 0.0000000000000000000000000000001417 130.0
HKD1_k127_2749670_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K18331 - 1.12.1.3 0.0 1064.0
HKD1_k127_2749670_1 FMN binding - - - 9.813e-244 762.0
HKD1_k127_2749670_10 KR domain - - - 0.00000008984 57.0
HKD1_k127_2749670_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 444.0
HKD1_k127_2749670_3 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 372.0
HKD1_k127_2749670_4 ABC transporter (Periplasmic binding protein) K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 369.0
HKD1_k127_2749670_5 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 356.0
HKD1_k127_2749670_6 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000256 259.0
HKD1_k127_2749670_7 with different specificities (related to short-chain alcohol - - - 0.0000000000000000000000000000000000000000003223 168.0
HKD1_k127_2777086_0 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 375.0
HKD1_k127_2777086_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 319.0
HKD1_k127_2777086_2 acyl-coa dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000002578 122.0
HKD1_k127_2777086_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000004425 67.0
HKD1_k127_2800589_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 600.0
HKD1_k127_2800589_1 Methyltransferase FkbM domain - - - 0.00000000000000000000000000006681 118.0
HKD1_k127_2800589_2 - - - - 0.00000000000000000000007175 108.0
HKD1_k127_2800589_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000001565 98.0
HKD1_k127_2818186_0 Trap dicarboxylate transporter, dctm subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 508.0
HKD1_k127_2818186_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 497.0
HKD1_k127_2818186_10 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000000000000000000000001195 226.0
HKD1_k127_2818186_11 Methyltransferase MtaA K14080 - 2.1.1.246 0.00000000000000000000000000000000000000000000000000000000000006447 226.0
HKD1_k127_2818186_12 with different specificities (related to short-chain alcohol - - - 0.000000000000000000000000000000000000000000000000000000000003338 218.0
HKD1_k127_2818186_13 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000393 196.0
HKD1_k127_2818186_14 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000389 182.0
HKD1_k127_2818186_15 Tripartite ATP-independent periplasmic transporter, DctQ - - - 0.0000000000000000000000000000000000000003882 154.0
HKD1_k127_2818186_16 Aldolase/RraA - - - 0.0000000000000000000000000000000000000004028 157.0
HKD1_k127_2818186_17 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000001 157.0
HKD1_k127_2818186_18 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000001096 148.0
HKD1_k127_2818186_19 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.00000000000000000000000001507 115.0
HKD1_k127_2818186_2 xylulokinase activity K00851,K00854 - 2.7.1.12,2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 469.0
HKD1_k127_2818186_20 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000002598 78.0
HKD1_k127_2818186_21 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000001299 75.0
HKD1_k127_2818186_3 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component K21393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 374.0
HKD1_k127_2818186_4 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 307.0
HKD1_k127_2818186_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005214 283.0
HKD1_k127_2818186_6 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004013 281.0
HKD1_k127_2818186_7 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000499 272.0
HKD1_k127_2818186_8 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.00000000000000000000000000000000000000000000000000000000000000000000000000002346 267.0
HKD1_k127_2818186_9 RpiR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000001878 243.0
HKD1_k127_2826826_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.99e-271 854.0
HKD1_k127_2826826_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 464.0
HKD1_k127_2826826_10 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003542 251.0
HKD1_k127_2826826_11 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000001021 227.0
HKD1_k127_2826826_12 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000001798 226.0
HKD1_k127_2826826_13 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000002217 218.0
HKD1_k127_2826826_14 Protein of unknown function DUF47 K02039,K07220 - - 0.000000000000000000000000000000000000000000000000000000000005406 213.0
HKD1_k127_2826826_15 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000507 204.0
HKD1_k127_2826826_16 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000001565 192.0
HKD1_k127_2826826_17 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000000000000000000000003566 158.0
HKD1_k127_2826826_19 PBP superfamily domain K05772 - - 0.00000000000000000000000000006991 119.0
HKD1_k127_2826826_2 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 426.0
HKD1_k127_2826826_20 Phosphoglycerate mutase family K08296 - - 0.00000000000000000002159 97.0
HKD1_k127_2826826_21 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000002744 89.0
HKD1_k127_2826826_22 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000006673 76.0
HKD1_k127_2826826_3 phosphate ion binding K02040 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 410.0
HKD1_k127_2826826_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 354.0
HKD1_k127_2826826_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 340.0
HKD1_k127_2826826_6 Male sterility protein K01710,K01784 - 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 339.0
HKD1_k127_2826826_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001865 290.0
HKD1_k127_2826826_8 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003135 256.0
HKD1_k127_2826826_9 response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002381 252.0
HKD1_k127_2848826_1 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 343.0
HKD1_k127_2848826_2 intracellular protease amidase K18199 - 4.2.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003555 283.0
HKD1_k127_2848826_3 - - - - 0.00000000000000000001357 100.0
HKD1_k127_2848826_4 Sugar (and other) transporter K08195 - - 0.000000049 60.0
HKD1_k127_2867166_0 Radical SAM K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 554.0
HKD1_k127_2867166_1 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000000000000001014 186.0
HKD1_k127_2867166_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000124 69.0
HKD1_k127_2867166_3 radical SAM domain protein - - - 0.00000001899 57.0
HKD1_k127_2869787_0 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 350.0
HKD1_k127_2869787_1 - K07497 - - 0.000000000000000000000000000000003941 132.0
HKD1_k127_2869787_2 Putative transposase of IS4/5 family (DUF4096) K07492 - - 0.000000000000255 71.0
HKD1_k127_2877526_0 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 1.902e-201 634.0
HKD1_k127_2877526_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006961 319.0
HKD1_k127_2877526_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000004743 189.0
HKD1_k127_2882528_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 496.0
HKD1_k127_2882528_1 Aminotransferase class-V - - - 0.000000005835 61.0
HKD1_k127_2882528_2 Protein tyrosine kinase - - - 0.000004884 52.0
HKD1_k127_2924382_0 DinB family - - - 0.000000000000000000000000000000000008657 143.0
HKD1_k127_2924382_1 YCII-related domain K09780 - - 0.000000000000000000000000000009202 124.0
HKD1_k127_2924382_2 - - - - 0.0000000005405 62.0
HKD1_k127_2924382_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01259 - 3.4.11.5 0.000000007675 68.0
HKD1_k127_2930498_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.136e-208 658.0
HKD1_k127_2930498_1 PFAM RNA polymerase sigma factor 54, interaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 563.0
HKD1_k127_2930498_10 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000001066 228.0
HKD1_k127_2930498_13 Peptidase S46 - - - 0.0000000000000000000000000001204 130.0
HKD1_k127_2930498_14 rRNA (guanine-N2-)-methyltransferase activity - - - 0.000000000000000000000002477 113.0
HKD1_k127_2930498_15 META domain - - - 0.000000000000000000000002485 109.0
HKD1_k127_2930498_16 Na -dependent transporter K03453 - - 0.00000000000005521 82.0
HKD1_k127_2930498_17 - - - - 0.00000000003415 66.0
HKD1_k127_2930498_18 - - - - 0.000000003114 61.0
HKD1_k127_2930498_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 530.0
HKD1_k127_2930498_3 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 497.0
HKD1_k127_2930498_4 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 418.0
HKD1_k127_2930498_5 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 335.0
HKD1_k127_2930498_6 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 323.0
HKD1_k127_2930498_7 acetylesterase activity K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 298.0
HKD1_k127_2930498_8 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000002169 264.0
HKD1_k127_2930498_9 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000001354 249.0
HKD1_k127_2932881_0 L-seryl-tRNA selenium transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 396.0
HKD1_k127_2932881_1 - - - - 0.0000000000000000001997 94.0
HKD1_k127_2932881_2 carboxymuconolactone decarboxylase - - - 0.0000000003685 64.0
HKD1_k127_2932881_3 Copper binding proteins, plastocyanin/azurin family - - - 0.000005413 55.0
HKD1_k127_2932881_4 Peptidase M50 - - - 0.0002896 45.0
HKD1_k127_294700_0 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 463.0
HKD1_k127_294700_1 Glycosyl transferase 4-like domain K00786 - - 0.000000000000000000000000000000000000000000000000042 192.0
HKD1_k127_294700_2 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000000121 171.0
HKD1_k127_294700_3 PAP2 superfamily C-terminal - - - 0.0000000000000000000000000000000000000000001105 170.0
HKD1_k127_294700_4 PFAM zinc finger, DksA TraR C4-type - - - 0.00000000001615 72.0
HKD1_k127_294700_5 Multicopper oxidase K00368,K18683,K22348 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.16.3.3,1.7.2.1 0.00000003742 61.0
HKD1_k127_3015181_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 524.0
HKD1_k127_3015181_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000001905 160.0
HKD1_k127_3015181_2 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000152 82.0
HKD1_k127_3015181_3 ABC transporter substrate binding protein K01989 - - 0.00000000000009111 71.0
HKD1_k127_3015181_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000006705 57.0
HKD1_k127_3015181_5 AhpC Tsa family - - - 0.00000001156 60.0
HKD1_k127_3015181_6 Belongs to the 'phage' integrase family - - - 0.00002251 52.0
HKD1_k127_3015639_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1351.0
HKD1_k127_3015639_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain K06445 - - 2.375e-320 1000.0
HKD1_k127_3015639_10 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 420.0
HKD1_k127_3015639_11 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 411.0
HKD1_k127_3015639_12 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 408.0
HKD1_k127_3015639_13 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 374.0
HKD1_k127_3015639_14 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 353.0
HKD1_k127_3015639_15 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 368.0
HKD1_k127_3015639_16 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 338.0
HKD1_k127_3015639_17 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 353.0
HKD1_k127_3015639_18 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 335.0
HKD1_k127_3015639_19 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009238 320.0
HKD1_k127_3015639_2 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 2.25e-240 760.0
HKD1_k127_3015639_20 Aldose 1-epimerase K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 314.0
HKD1_k127_3015639_21 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 317.0
HKD1_k127_3015639_22 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 316.0
HKD1_k127_3015639_23 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 295.0
HKD1_k127_3015639_24 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000144 299.0
HKD1_k127_3015639_25 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007543 278.0
HKD1_k127_3015639_26 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01003,K01841 - 4.1.1.3,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 267.0
HKD1_k127_3015639_27 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000001361 167.0
HKD1_k127_3015639_28 AsmA-like C-terminal region - - - 0.00000000000000000000000000000000000001173 169.0
HKD1_k127_3015639_29 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000001212 118.0
HKD1_k127_3015639_3 2-methylcitrate dehydratase K01720 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0047547,GO:0071704 4.2.1.79 1.395e-208 664.0
HKD1_k127_3015639_30 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000004851 113.0
HKD1_k127_3015639_31 TOBE domain - - - 0.00000000000000000001411 96.0
HKD1_k127_3015639_32 DUF218 domain - - - 0.000000000000002254 85.0
HKD1_k127_3015639_33 Phosphorylase superfamily K01243 - 3.2.2.9 0.0000000000001835 78.0
HKD1_k127_3015639_34 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 4.2.1.17 0.0004192 48.0
HKD1_k127_3015639_4 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 552.0
HKD1_k127_3015639_5 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 521.0
HKD1_k127_3015639_6 Citrate synthase, C-terminal domain K01659 - 2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 482.0
HKD1_k127_3015639_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 469.0
HKD1_k127_3015639_8 Transporter associated domain K03699,K06189 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 470.0
HKD1_k127_3015639_9 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 445.0
HKD1_k127_3016341_0 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 496.0
HKD1_k127_3016341_1 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 344.0
HKD1_k127_3016341_10 Transposase IS200 like - - - 0.00003713 54.0
HKD1_k127_3016341_11 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0003764 51.0
HKD1_k127_3016341_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 295.0
HKD1_k127_3016341_3 NMT1/THI5 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001392 291.0
HKD1_k127_3016341_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000002981 235.0
HKD1_k127_3016341_5 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000001987 226.0
HKD1_k127_3016341_6 transcriptional K03710 - - 0.000000000000000000000000000000000000000749 158.0
HKD1_k127_3016341_7 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000005248 114.0
HKD1_k127_3016341_8 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000004311 96.0
HKD1_k127_3016341_9 - - - - 0.00000000004628 72.0
HKD1_k127_3016557_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000004466 239.0
HKD1_k127_3016557_1 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000000002657 187.0
HKD1_k127_3016557_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000008935 154.0
HKD1_k127_3016557_3 RNA recognition motif - - - 0.000000000000000000000000000000000000001893 150.0
HKD1_k127_3016557_4 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001603 93.0
HKD1_k127_3016557_5 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000004868 95.0
HKD1_k127_3016557_7 Lrp/AsnC ligand binding domain - - - 0.00001211 54.0
HKD1_k127_3016557_8 EF hand - - - 0.0008996 43.0
HKD1_k127_3024580_0 Domain of unknown function (DUF3459) K00700,K01236 - 2.4.1.18,3.2.1.141 2.166e-199 642.0
HKD1_k127_3024580_1 Response regulator receiver K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 432.0
HKD1_k127_3024580_10 COG1555 DNA uptake protein and related DNA-binding proteins K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00003664 51.0
HKD1_k127_3024580_11 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00007828 46.0
HKD1_k127_3024580_2 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 364.0
HKD1_k127_3024580_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006764 284.0
HKD1_k127_3024580_4 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000001948 254.0
HKD1_k127_3024580_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000002672 221.0
HKD1_k127_3024580_6 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000008001 111.0
HKD1_k127_3024580_7 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000007142 101.0
HKD1_k127_3024580_8 NADPH-dependent FMN reductase - - - 0.000000000009608 75.0
HKD1_k127_3024580_9 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000005003 58.0
HKD1_k127_3027780_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 2.537e-205 651.0
HKD1_k127_3027780_1 mannitol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 599.0
HKD1_k127_3027780_10 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000000000000000000000000000000008367 183.0
HKD1_k127_3027780_11 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000002308 87.0
HKD1_k127_3027780_2 carbohydrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 507.0
HKD1_k127_3027780_3 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 395.0
HKD1_k127_3027780_4 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 348.0
HKD1_k127_3027780_5 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 346.0
HKD1_k127_3027780_6 KduI/IolB family K03337 - 5.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 343.0
HKD1_k127_3027780_7 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 346.0
HKD1_k127_3027780_8 PFAM oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009377 264.0
HKD1_k127_3027780_9 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000006562 227.0
HKD1_k127_3036967_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000008973 226.0
HKD1_k127_3036967_1 - - - - 0.00000000000000000000000001614 114.0
HKD1_k127_3037373_0 Required for chromosome condensation and partitioning K03529 - - 1.362e-243 795.0
HKD1_k127_3037373_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 596.0
HKD1_k127_3037373_10 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 422.0
HKD1_k127_3037373_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 329.0
HKD1_k127_3037373_12 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 308.0
HKD1_k127_3037373_13 PFAM glutamine amidotransferase class-I K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 285.0
HKD1_k127_3037373_14 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000004105 267.0
HKD1_k127_3037373_15 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000007169 252.0
HKD1_k127_3037373_16 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000001986 232.0
HKD1_k127_3037373_17 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000002247 205.0
HKD1_k127_3037373_18 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000001039 210.0
HKD1_k127_3037373_19 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000104 205.0
HKD1_k127_3037373_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K01497,K02858,K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 580.0
HKD1_k127_3037373_20 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000002213 209.0
HKD1_k127_3037373_21 translation initiation factor activity - - - 0.00000000000000000000000000000000000000000000000003476 199.0
HKD1_k127_3037373_22 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000007679 151.0
HKD1_k127_3037373_23 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000002527 133.0
HKD1_k127_3037373_24 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000001828 132.0
HKD1_k127_3037373_25 translation initiation factor activity - - - 0.000000000000000000000000000001032 130.0
HKD1_k127_3037373_26 PFAM phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000001592 129.0
HKD1_k127_3037373_27 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000161 121.0
HKD1_k127_3037373_28 PFAM Fimbrial assembly family protein K02662,K02663 - - 0.0000000000000000000001563 104.0
HKD1_k127_3037373_29 protein transport across the cell outer membrane K02246,K08084 - - 0.00000000004941 71.0
HKD1_k127_3037373_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 562.0
HKD1_k127_3037373_30 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000312 59.0
HKD1_k127_3037373_31 AMP-binding enzyme C-terminal domain - - - 0.000000579 59.0
HKD1_k127_3037373_32 pilus assembly protein PilW - - - 0.000005733 56.0
HKD1_k127_3037373_33 type IV pilus modification protein PilV K02459,K02671 - - 0.0005764 50.0
HKD1_k127_3037373_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 520.0
HKD1_k127_3037373_5 polysaccharide export K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 509.0
HKD1_k127_3037373_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 434.0
HKD1_k127_3037373_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 414.0
HKD1_k127_3037373_8 PFAM NAD binding domain of 6-phosphogluconate dehydrogenase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 410.0
HKD1_k127_3037373_9 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 402.0
HKD1_k127_3042349_0 Insecticidal toxin complex protein TcaC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 394.0
HKD1_k127_3042349_1 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 321.0
HKD1_k127_3048589_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 574.0
HKD1_k127_3048589_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 517.0
HKD1_k127_3048589_10 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 290.0
HKD1_k127_3048589_11 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001872 256.0
HKD1_k127_3048589_12 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000001859 246.0
HKD1_k127_3048589_13 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000001368 218.0
HKD1_k127_3048589_14 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000006365 198.0
HKD1_k127_3048589_15 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000409 193.0
HKD1_k127_3048589_16 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05796 - - 0.00000000000000000000000000000000000000000000000003628 183.0
HKD1_k127_3048589_17 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000008965 190.0
HKD1_k127_3048589_18 DnaJ molecular chaperone homology domain K05516 - - 0.000000000000000000000000000000000000000000001298 179.0
HKD1_k127_3048589_19 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000003359 149.0
HKD1_k127_3048589_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 470.0
HKD1_k127_3048589_20 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000003612 149.0
HKD1_k127_3048589_21 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000003305 139.0
HKD1_k127_3048589_22 CBS domain - - - 0.00000000000000000000000000000005625 133.0
HKD1_k127_3048589_23 Smr domain - - - 0.0000000000000000000000000000818 122.0
HKD1_k127_3048589_24 Evidence 5 No homology to any previously reported sequences K08303 - - 0.000000000000000000000002587 106.0
HKD1_k127_3048589_25 Putative regulatory protein - - - 0.0000000004272 63.0
HKD1_k127_3048589_26 PFAM peptidase M48 Ste24p - - - 0.00001992 49.0
HKD1_k127_3048589_3 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 446.0
HKD1_k127_3048589_4 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 422.0
HKD1_k127_3048589_5 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 391.0
HKD1_k127_3048589_6 Zn-dependent hydrolase, glyoxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 354.0
HKD1_k127_3048589_7 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 341.0
HKD1_k127_3048589_8 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 307.0
HKD1_k127_3048589_9 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 307.0
HKD1_k127_3053974_0 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 465.0
HKD1_k127_3053974_1 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 385.0
HKD1_k127_3053974_2 Binding-protein-dependent transport system inner membrane component K10229 - - 0.0000000000000000000000000000002421 124.0
HKD1_k127_3053974_3 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.0000005297 56.0
HKD1_k127_3055558_0 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 563.0
HKD1_k127_3055558_1 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 565.0
HKD1_k127_3058656_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 304.0
HKD1_k127_3058656_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000001086 123.0
HKD1_k127_3068816_0 PFAM Aminotransferase class I and II K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 428.0
HKD1_k127_3068816_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000104 190.0
HKD1_k127_3068816_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000006301 81.0
HKD1_k127_3077747_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002309 279.0
HKD1_k127_3077747_1 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000006179 217.0
HKD1_k127_3077747_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000004311 205.0
HKD1_k127_3077747_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000001147 113.0
HKD1_k127_3079204_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 502.0
HKD1_k127_3079204_1 - - - - 0.00000000000001006 76.0
HKD1_k127_3084860_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 613.0
HKD1_k127_3084860_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 578.0
HKD1_k127_3084860_10 GGDEF domain - - - 0.000000000000000000008431 97.0
HKD1_k127_3084860_2 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008885 424.0
HKD1_k127_3084860_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 419.0
HKD1_k127_3084860_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 350.0
HKD1_k127_3084860_5 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 303.0
HKD1_k127_3084860_6 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000001728 220.0
HKD1_k127_3084860_7 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000001629 205.0
HKD1_k127_3084860_8 PFAM Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.00000000000000000000000000000000000000000000324 170.0
HKD1_k127_3084860_9 Protein of unknown function (DUF1232) - - - 0.00000000000000000000003734 105.0
HKD1_k127_3122671_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 2.943e-205 646.0
HKD1_k127_3122671_1 oxaloacetate decarboxylase activity K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 538.0
HKD1_k127_3122671_2 PFAM carboxyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 478.0
HKD1_k127_3122671_3 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 327.0
HKD1_k127_3122671_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003167 277.0
HKD1_k127_3122671_5 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001275 212.0
HKD1_k127_3122671_6 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000004861 190.0
HKD1_k127_3122671_7 CoA carboxylase activity K01965 - 6.4.1.3 0.0000000000000000000000000003253 120.0
HKD1_k127_3122671_8 sodium ion export across plasma membrane K01573 GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234 4.1.1.3 0.0000000000000000000002363 101.0
HKD1_k127_3126408_0 Belongs to the ompA family K03286 - - 0.0007604 49.0
HKD1_k127_3141041_0 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001422 245.0
HKD1_k127_3141041_1 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000003529 244.0
HKD1_k127_3141041_2 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000000000000000000000000000000000000001642 152.0
HKD1_k127_3141041_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000002986 147.0
HKD1_k127_3141041_4 HicB family K18843 - - 0.000000000000000000000000000000000000003399 149.0
HKD1_k127_3141041_5 Transposase IS200 like - - - 0.00000000000000000000000000000001529 133.0
HKD1_k127_3141041_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000008103 91.0
HKD1_k127_3141041_7 SMART Chromosomal replication initiator DnaA domain - - - 0.0005876 47.0
HKD1_k127_3155734_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 4.551e-247 767.0
HKD1_k127_3155734_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 565.0
HKD1_k127_3155734_10 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 299.0
HKD1_k127_3155734_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003515 280.0
HKD1_k127_3155734_12 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000002545 269.0
HKD1_k127_3155734_13 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000001404 277.0
HKD1_k127_3155734_14 Phosphoribosyl-AMP cyclohydrolase K01496,K01497,K01523,K01814,K11755 GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000001021 261.0
HKD1_k127_3155734_15 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002556 248.0
HKD1_k127_3155734_16 Imidazoleglycerol-phosphate dehydratase K00013,K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000001998 240.0
HKD1_k127_3155734_17 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000001241 229.0
HKD1_k127_3155734_18 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000007638 225.0
HKD1_k127_3155734_19 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000044 220.0
HKD1_k127_3155734_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 535.0
HKD1_k127_3155734_20 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859,K07566 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.87 0.0000000000000000000000000000000000000000000000007467 182.0
HKD1_k127_3155734_21 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000003032 179.0
HKD1_k127_3155734_22 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000002457 177.0
HKD1_k127_3155734_23 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000003225 142.0
HKD1_k127_3155734_24 - - - - 0.0000000000000000000000000001383 121.0
HKD1_k127_3155734_25 Binds the 23S rRNA K02909 GO:0008150,GO:0040007 - 0.000000000000000000000000003845 112.0
HKD1_k127_3155734_26 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000005434 94.0
HKD1_k127_3155734_27 Domain of unknown function (DUF4382) - - - 0.000003379 60.0
HKD1_k127_3155734_28 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.0000323 55.0
HKD1_k127_3155734_29 - - - - 0.000408 43.0
HKD1_k127_3155734_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 496.0
HKD1_k127_3155734_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 484.0
HKD1_k127_3155734_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 462.0
HKD1_k127_3155734_6 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 462.0
HKD1_k127_3155734_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500,K11755 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 380.0
HKD1_k127_3155734_8 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 362.0
HKD1_k127_3155734_9 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 344.0
HKD1_k127_3155855_0 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 6.898e-194 616.0
HKD1_k127_3155855_1 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002933 267.0
HKD1_k127_3155855_2 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000001399 226.0
HKD1_k127_3155855_3 Surface antigen - - - 0.000000000000002187 81.0
HKD1_k127_3155855_4 - - - - 0.0000395 46.0
HKD1_k127_3165933_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 8.937e-243 768.0
HKD1_k127_3165933_1 Domain of unknown function (DUF3463) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 448.0
HKD1_k127_3165933_2 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000002598 218.0
HKD1_k127_3172060_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 535.0
HKD1_k127_3173040_0 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 1.503e-269 839.0
HKD1_k127_3173040_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 2.067e-194 621.0
HKD1_k127_3173040_10 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000000000000001055 116.0
HKD1_k127_3173040_11 CAAX protease self-immunity K07052 - - 0.00000032 61.0
HKD1_k127_3173040_12 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000002418 57.0
HKD1_k127_3173040_2 Tripartite tricarboxylate transporter TctA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 561.0
HKD1_k127_3173040_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 514.0
HKD1_k127_3173040_4 protein conserved in bacteria K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 486.0
HKD1_k127_3173040_5 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000915 286.0
HKD1_k127_3173040_6 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001372 286.0
HKD1_k127_3173040_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001637 248.0
HKD1_k127_3173040_8 PFAM AzlC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002355 244.0
HKD1_k127_3173040_9 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000002911 121.0
HKD1_k127_3173730_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 553.0
HKD1_k127_3173730_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000002238 53.0
HKD1_k127_3187676_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 1.36e-237 751.0
HKD1_k127_3187676_1 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 6.275e-218 695.0
HKD1_k127_3187676_10 PFAM Haloacid dehalogenase domain protein hydrolase K02566 - - 0.0000000000000000000000000000000000000000000000000000002621 203.0
HKD1_k127_3187676_11 - - - - 0.0000000000000000000000000000000000000000000000000000009547 198.0
HKD1_k127_3187676_12 peptidyl-prolyl cis-trans isomerase activity K03770,K07533 - 5.2.1.8 0.000000000000000000000000000000000000000000000000001345 195.0
HKD1_k127_3187676_13 - - - - 0.00000000000000000000000000000000001854 141.0
HKD1_k127_3187676_15 ABC transporter permease - - - 0.0000000000000000000000000007984 113.0
HKD1_k127_3187676_16 rod shape-determining protein MreD K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00000000000000000000000001432 115.0
HKD1_k127_3187676_17 cheY-homologous receiver domain K11443 - - 0.00000000000000000001586 98.0
HKD1_k127_3187676_18 Nodulation protein S (NodS) - - - 0.000002045 57.0
HKD1_k127_3187676_19 E3 ubiquitin-protein ligase CBL K04707 GO:0000003,GO:0000209,GO:0001654,GO:0001667,GO:0001745,GO:0001751,GO:0001752,GO:0001754,GO:0001784,GO:0001894,GO:0001932,GO:0001933,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0003002,GO:0003006,GO:0003674,GO:0003700,GO:0003824,GO:0004842,GO:0005102,GO:0005154,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005912,GO:0005924,GO:0005925,GO:0005938,GO:0006109,GO:0006355,GO:0006464,GO:0006468,GO:0006469,GO:0006508,GO:0006511,GO:0006513,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006897,GO:0006928,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007173,GO:0007175,GO:0007176,GO:0007178,GO:0007179,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007389,GO:0007399,GO:0007423,GO:0007444,GO:0007465,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0008069,GO:0008150,GO:0008152,GO:0008270,GO:0008283,GO:0008543,GO:0009056,GO:0009057,GO:0009653,GO:0009719,GO:0009791,GO:0009798,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009950,GO:0009953,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010469,GO:0010556,GO:0010563,GO:0010605,GO:0010631,GO:0010646,GO:0010647,GO:0010648,GO:0010817,GO:0010941,GO:0014066,GO:0014068,GO:0016020,GO:0016043,GO:0016192,GO:0016310,GO:0016333,GO:0016334,GO:0016477,GO:0016567,GO:0016740,GO:0017124,GO:0019219,GO:0019220,GO:0019221,GO:0019222,GO:0019538,GO:0019787,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0019941,GO:0019953,GO:0022008,GO:0022412,GO:0022414,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030054,GO:0030055,GO:0030100,GO:0030154,GO:0030163,GO:0030182,GO:0030260,GO:0030424,GO:0030426,GO:0030427,GO:0030707,GO:0030855,GO:0030971,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0032350,GO:0032351,GO:0032353,GO:0032446,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0033267,GO:0033673,GO:0034097,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0035635,GO:0036211,GO:0036312,GO:0038127,GO:0040011,GO:0040027,GO:0040028,GO:0042058,GO:0042059,GO:0042127,GO:0042221,GO:0042325,GO:0042326,GO:0042592,GO:0042706,GO:0042981,GO:0042995,GO:0043005,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043548,GO:0043549,GO:0043632,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044344,GO:0044403,GO:0044409,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044463,GO:0044464,GO:0044703,GO:0045121,GO:0045165,GO:0045309,GO:0045453,GO:0045466,GO:0045742,GO:0045807,GO:0045859,GO:0045936,GO:0046530,GO:0046552,GO:0046677,GO:0046849,GO:0046872,GO:0046875,GO:0046885,GO:0046914,GO:0048134,GO:0048259,GO:0048260,GO:0048468,GO:0048471,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048563,GO:0048569,GO:0048580,GO:0048581,GO:0048583,GO:0048584,GO:0048585,GO:0048592,GO:0048609,GO:0048663,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048749,GO:0048771,GO:0048856,GO:0048869,GO:0048870,GO:0048871,GO:0050730,GO:0050732,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051093,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051219,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051338,GO:0051348,GO:0051603,GO:0051674,GO:0051701,GO:0051704,GO:0051716,GO:0051806,GO:0051828,GO:0060249,GO:0060255,GO:0060429,GO:0060548,GO:0060562,GO:0060627,GO:0061024,GO:0061062,GO:0061064,GO:0061097,GO:0061099,GO:0061630,GO:0061659,GO:0065007,GO:0065008,GO:0065009,GO:0070102,GO:0070161,GO:0070647,GO:0070741,GO:0070848,GO:0070849,GO:0070851,GO:0070887,GO:0071310,GO:0071345,GO:0071354,GO:0071363,GO:0071364,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071774,GO:0071840,GO:0071944,GO:0080090,GO:0090130,GO:0090132,GO:0090596,GO:0097458,GO:0098589,GO:0098657,GO:0098805,GO:0098857,GO:0099568,GO:0120025,GO:0120038,GO:0140096,GO:0140110,GO:0150034,GO:1901184,GO:1901185,GO:1901186,GO:1901214,GO:1901215,GO:1901564,GO:1901565,GO:1901575,GO:1902531,GO:1902533,GO:1903506,GO:1990782,GO:2000026,GO:2000112,GO:2000272,GO:2001141 2.3.2.27 0.0008175 45.0
HKD1_k127_3187676_2 MreB/Mbl protein K03569 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 595.0
HKD1_k127_3187676_3 TOBE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 437.0
HKD1_k127_3187676_4 PFAM extracellular solute-binding protein family 1 K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 403.0
HKD1_k127_3187676_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 392.0
HKD1_k127_3187676_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K11072 - 3.6.3.30,3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 385.0
HKD1_k127_3187676_7 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001795 272.0
HKD1_k127_3187676_8 Cell shape-determining protein MreC K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - 0.0000000000000000000000000000000000000000000000000000000000000000003736 240.0
HKD1_k127_3187676_9 PFAM Short-chain dehydrogenase reductase SDR K00046,K00065 - 1.1.1.127,1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000003698 229.0
HKD1_k127_3194053_0 Glycosyl hydrolases family 15 - - - 2.912e-266 833.0
HKD1_k127_3194053_1 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 412.0
HKD1_k127_3194053_2 Phosphotransferase enzyme family K00700,K05343,K16146 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,2.7.1.175,3.2.1.1,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 308.0
HKD1_k127_3194053_3 Glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000003958 244.0
HKD1_k127_3194053_4 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000001644 207.0
HKD1_k127_3194053_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000117 121.0
HKD1_k127_3200268_0 Sulfatase K01130 - 3.1.6.1 7.242e-303 936.0
HKD1_k127_3200268_1 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 405.0
HKD1_k127_3200268_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000004689 213.0
HKD1_k127_3200268_3 Protein of unknown function (DUF992) - - - 0.000000000000000000000000000006807 126.0
HKD1_k127_3203902_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 498.0
HKD1_k127_3203902_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 299.0
HKD1_k127_3203902_2 Putative transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 292.0
HKD1_k127_3203902_3 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.00000000496 60.0
HKD1_k127_3216293_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 5.675e-204 643.0
HKD1_k127_3216293_1 Acetamidase formamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 552.0
HKD1_k127_3216293_10 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 339.0
HKD1_k127_3216293_11 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 316.0
HKD1_k127_3216293_12 DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006473 261.0
HKD1_k127_3216293_13 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000002043 247.0
HKD1_k127_3216293_14 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000001711 203.0
HKD1_k127_3216293_15 response regulator, receiver - - - 0.0000000000000000000000001537 112.0
HKD1_k127_3216293_16 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000002341 121.0
HKD1_k127_3216293_17 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.00000000000000009813 85.0
HKD1_k127_3216293_19 Tetratricopeptide repeat protein - - - 0.0001991 51.0
HKD1_k127_3216293_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 506.0
HKD1_k127_3216293_20 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway - - - 0.0004646 47.0
HKD1_k127_3216293_3 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 505.0
HKD1_k127_3216293_4 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 513.0
HKD1_k127_3216293_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 443.0
HKD1_k127_3216293_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 400.0
HKD1_k127_3216293_7 PFAM ABC transporter related K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 372.0
HKD1_k127_3216293_8 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 374.0
HKD1_k127_3216293_9 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 349.0
HKD1_k127_3229372_0 Protein of unknown function, DUF255 K06888 - - 0.0 1409.0
HKD1_k127_3229372_1 CHAT domain - - - 1.001e-205 670.0
HKD1_k127_3229372_10 photosynthesis - - - 0.00000000000000000000000000000000000000000000000008005 185.0
HKD1_k127_3229372_12 DoxX K03885,K16937 - 1.6.99.3,1.8.5.2 0.000000000000000000000007357 107.0
HKD1_k127_3229372_13 (Rhomboid) family - - - 0.00000000005589 75.0
HKD1_k127_3229372_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 437.0
HKD1_k127_3229372_3 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 394.0
HKD1_k127_3229372_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 382.0
HKD1_k127_3229372_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 358.0
HKD1_k127_3229372_6 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 317.0
HKD1_k127_3229372_7 PFAM Xylose isomerase domain protein TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 301.0
HKD1_k127_3229372_8 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007734 246.0
HKD1_k127_3229372_9 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000118 205.0
HKD1_k127_3244261_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 615.0
HKD1_k127_3244261_1 alpha beta K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001241 259.0
HKD1_k127_3244261_2 - - - - 0.00000000000000000000000000007835 119.0
HKD1_k127_3244261_3 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000005482 104.0
HKD1_k127_3244261_4 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000002779 93.0
HKD1_k127_3244261_5 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000008227 85.0
HKD1_k127_3244261_6 - - - - 0.000001617 57.0
HKD1_k127_3251007_0 Chitobiase/beta-hexosaminidase C-terminal domain - - - 1.1e-208 670.0
HKD1_k127_3251007_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 613.0
HKD1_k127_3251007_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 525.0
HKD1_k127_3251007_3 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 463.0
HKD1_k127_3251007_4 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 412.0
HKD1_k127_3251007_5 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 GO:0003674,GO:0003824,GO:0008808,GO:0016740,GO:0016772,GO:0016780,GO:0030572 - 0.00000000000000000008105 95.0
HKD1_k127_3258660_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 5.978e-320 1003.0
HKD1_k127_3258660_1 Type II/IV secretion system protein K02454,K02652 - - 3.182e-273 865.0
HKD1_k127_3258660_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.417e-218 693.0
HKD1_k127_3258660_3 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 534.0
HKD1_k127_3258660_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000004045 244.0
HKD1_k127_3258660_5 Type III restriction K01153 - 3.1.21.3 0.0000000000000000000000000000000000000000163 161.0
HKD1_k127_3273353_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 412.0
HKD1_k127_3273353_1 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002843 277.0
HKD1_k127_3279306_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.241e-204 649.0
HKD1_k127_3279306_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 487.0
HKD1_k127_3279306_2 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K12137 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 390.0
HKD1_k127_3279306_3 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 304.0
HKD1_k127_3279306_4 ACT domain - - - 0.00000000000000000000000000000000000000000000000000003226 191.0
HKD1_k127_3279306_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000001742 80.0
HKD1_k127_3280499_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 1.887e-225 713.0
HKD1_k127_3280499_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005587 279.0
HKD1_k127_3280499_2 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000412 175.0
HKD1_k127_3280499_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000229 127.0
HKD1_k127_3280499_4 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000004179 108.0
HKD1_k127_3280499_5 Protein of unknown function (DUF3300) - - - 0.0000000000008425 72.0
HKD1_k127_3280499_6 Cupin 2, conserved barrel domain protein K14673 - - 0.00001965 48.0
HKD1_k127_3283083_0 COG5433 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 358.0
HKD1_k127_3283083_1 Transposase - - - 0.000000000000000000000000000000000000000000006124 165.0
HKD1_k127_3283083_2 COG NOG11635 non supervised orthologous group - - - 0.00000003508 60.0
HKD1_k127_3289734_0 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 539.0
HKD1_k127_3289734_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 462.0
HKD1_k127_3289734_2 Pyruvate flavodoxin ferredoxin K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 325.0
HKD1_k127_3289734_3 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000002919 249.0
HKD1_k127_3315602_0 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000781 632.0
HKD1_k127_3315602_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 308.0
HKD1_k127_3315602_2 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001593 255.0
HKD1_k127_3315602_3 Periplasmic binding protein K01999 - - 0.0000001389 53.0
HKD1_k127_3315602_4 Periplasmic binding protein K01999 - - 0.0001024 46.0
HKD1_k127_3333505_0 DEAD DEAH box K03724 - - 0.0 1492.0
HKD1_k127_3333505_1 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 488.0
HKD1_k127_3333505_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 317.0
HKD1_k127_3333505_3 Belongs to the FPG family K05522 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000003098 224.0
HKD1_k127_3333505_4 Protein conserved in bacteria - - - 0.00000000002502 71.0
HKD1_k127_3345801_0 SAF K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 454.0
HKD1_k127_3345801_1 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 426.0
HKD1_k127_3345801_2 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 388.0
HKD1_k127_3345801_3 FCD - - - 0.00000000000000000000000000000000000000000000006672 179.0
HKD1_k127_3345801_4 transporter, DctM subunit - - - 0.00001963 47.0
HKD1_k127_3349417_0 radical SAM domain protein K04034 - 1.21.98.3 1.161e-256 801.0
HKD1_k127_3349417_1 FAD binding domain K00278,K03388 - 1.4.3.16,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 617.0
HKD1_k127_3349417_10 ATPases associated with a variety of cellular activities K02028,K09972 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 344.0
HKD1_k127_3349417_11 PFAM short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 320.0
HKD1_k127_3349417_12 ABC transporter (Permease) K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 314.0
HKD1_k127_3349417_13 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001605 267.0
HKD1_k127_3349417_14 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003603 271.0
HKD1_k127_3349417_15 Beta-lactamase superfamily domain K03476 - - 0.00000000000000000000000000000000000000000000000000000000000000504 227.0
HKD1_k127_3349417_16 2-keto-3-deoxy-L-rhamnonate aldolase activity K01630,K02510 - 4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000121 225.0
HKD1_k127_3349417_17 L-seryl-tRNA selenium transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000306 218.0
HKD1_k127_3349417_18 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.0000000000000000000000000000000000000000000000000000000001027 213.0
HKD1_k127_3349417_19 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000004292 218.0
HKD1_k127_3349417_2 C oxidoreductase subunit A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 448.0
HKD1_k127_3349417_20 ABC transporter K02029,K10037 - - 0.0000000000000000000000000000000000000000000000000000001702 202.0
HKD1_k127_3349417_21 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000003327 179.0
HKD1_k127_3349417_22 COGs COG4087 Soluble P-type ATPase - - - 0.0000000000000000000000000000000000000975 147.0
HKD1_k127_3349417_23 methyltransferase - - - 0.000000000000000000000000000000000001064 147.0
HKD1_k127_3349417_24 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000005328 125.0
HKD1_k127_3349417_25 Pfam Secreted repeat of K19519 - - 0.0000000000000000000000000006517 120.0
HKD1_k127_3349417_26 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000006259 88.0
HKD1_k127_3349417_27 TIGRFAM Protein of - - - 0.000000000000000005052 86.0
HKD1_k127_3349417_28 - - - - 0.0000000000000002433 85.0
HKD1_k127_3349417_29 Cytochrome c - - - 0.0000000000000004921 81.0
HKD1_k127_3349417_3 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000678 422.0
HKD1_k127_3349417_30 sodium-dependent phosphate transmembrane transporter activity - - - 0.0000002782 62.0
HKD1_k127_3349417_4 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 418.0
HKD1_k127_3349417_5 Belongs to the bacterial solute-binding protein 3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 399.0
HKD1_k127_3349417_6 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 387.0
HKD1_k127_3349417_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 379.0
HKD1_k127_3349417_8 PFAM LOR SDH bifunctional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 393.0
HKD1_k127_3349417_9 ABC transporter, ATP-binding protein K02028,K09972 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 351.0
HKD1_k127_3367990_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 4.743e-234 743.0
HKD1_k127_3367990_1 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 506.0
HKD1_k127_3367990_2 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 458.0
HKD1_k127_3367990_3 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000001311 224.0
HKD1_k127_3369754_0 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.0 1108.0
HKD1_k127_3369754_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 1.261e-281 873.0
HKD1_k127_3369754_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000001983 156.0
HKD1_k127_3369754_11 Iron-sulfur cluster-binding domain K06871 - - 0.00000000000000000000000000000000005692 135.0
HKD1_k127_3369754_12 Antibiotic biosynthesis monooxygenase K01056 GO:0003674,GO:0003824 3.1.1.29 0.000000000000000000003429 98.0
HKD1_k127_3369754_13 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000004549 63.0
HKD1_k127_3369754_14 - - - - 0.000000001053 61.0
HKD1_k127_3369754_15 Iron-sulfur cluster-binding domain K06871 - - 0.0000002489 60.0
HKD1_k127_3369754_16 Protein of unknown function (DUF433) - - - 0.000006587 48.0
HKD1_k127_3369754_17 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0002171 48.0
HKD1_k127_3369754_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 506.0
HKD1_k127_3369754_3 nitrogen compound transport K02033 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 392.0
HKD1_k127_3369754_4 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 362.0
HKD1_k127_3369754_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 352.0
HKD1_k127_3369754_6 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 348.0
HKD1_k127_3369754_7 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 359.0
HKD1_k127_3369754_8 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000008599 234.0
HKD1_k127_3369754_9 - - - - 0.0000000000000000000000000000000000000000000000007497 178.0
HKD1_k127_3401464_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 608.0
HKD1_k127_3401464_1 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 490.0
HKD1_k127_3401464_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000006209 253.0
HKD1_k127_3401464_3 Putative nucleotide-binding of sugar-metabolising enzyme K22129 - 2.7.1.219,2.7.1.220 0.000000000000000000000000000000000000000000000000000000000002636 228.0
HKD1_k127_3401464_4 VKc - - - 0.0000000000000008089 83.0
HKD1_k127_3401464_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000002638 81.0
HKD1_k127_3410016_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000334 293.0
HKD1_k127_3422984_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 407.0
HKD1_k127_3422984_1 Protein export membrane protein K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 380.0
HKD1_k127_3422984_2 Iron-containing alcohol dehydrogenase K13954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 349.0
HKD1_k127_3422984_3 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 315.0
HKD1_k127_3422984_4 alcohol dehydrogenase K00004 - 1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000002506 203.0
HKD1_k127_3422984_5 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000003526 117.0
HKD1_k127_3422984_6 membrane - - - 0.000000000008919 76.0
HKD1_k127_3422984_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000001952 55.0
HKD1_k127_3422984_8 Enoyl-(Acyl carrier protein) reductase - - - 0.000008012 50.0
HKD1_k127_342712_0 thiamine pyrophosphate protein TPP binding domain protein K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 1.427e-278 867.0
HKD1_k127_342712_1 Ribosomal protein S1 K02945,K03527,K07571 - 1.17.7.4 4.378e-272 850.0
HKD1_k127_342712_10 Kinase/pyrophosphorylase K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000604 273.0
HKD1_k127_342712_11 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000002074 250.0
HKD1_k127_342712_12 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000891 211.0
HKD1_k127_342712_13 Belongs to the cytidylate kinase family. Type 1 subfamily K00800,K00945,K03977 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.19,2.7.4.25 0.000000000000000000000000000000000000000000000000000000003298 209.0
HKD1_k127_342712_14 Hit family K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000002837 196.0
HKD1_k127_342712_15 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000001545 181.0
HKD1_k127_342712_16 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K05788 - - 0.0000000000000000000000000000000000004086 141.0
HKD1_k127_342712_17 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000003907 145.0
HKD1_k127_342712_18 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000001363 152.0
HKD1_k127_342712_19 sequence-specific DNA binding - - - 0.0000000000001215 82.0
HKD1_k127_342712_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 541.0
HKD1_k127_342712_20 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000005586 67.0
HKD1_k127_342712_23 Domain of unknown function (DUF4845) - - - 0.000308 49.0
HKD1_k127_342712_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 435.0
HKD1_k127_342712_4 PFAM Na Picotransporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 421.0
HKD1_k127_342712_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 377.0
HKD1_k127_342712_6 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 363.0
HKD1_k127_342712_7 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 297.0
HKD1_k127_342712_8 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 286.0
HKD1_k127_342712_9 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008322 289.0
HKD1_k127_3454260_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000007031 223.0
HKD1_k127_3454260_1 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000004809 71.0
HKD1_k127_3454260_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000004146 64.0
HKD1_k127_3456094_0 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 449.0
HKD1_k127_3456094_1 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 383.0
HKD1_k127_3456094_2 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 301.0
HKD1_k127_3456094_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000364 82.0
HKD1_k127_3458691_0 UDP-glucoronosyl and UDP-glucosyl transferase K16444 - 2.4.1.310 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 469.0
HKD1_k127_3458691_1 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 316.0
HKD1_k127_3458691_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000003407 165.0
HKD1_k127_3477181_0 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 319.0
HKD1_k127_3477181_1 COG5659 FOG Transposase - - - 0.000000000000000000000000000000000000000000000000000233 190.0
HKD1_k127_3485928_0 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 468.0
HKD1_k127_3485928_1 ABC 3 transport family K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001001 274.0
HKD1_k127_3485928_2 AAA domain, putative AbiEii toxin, Type IV TA system K09820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001138 263.0
HKD1_k127_3485928_3 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.000000000000000000000000000000000000000000000000000000000000004671 229.0
HKD1_k127_3485928_4 PFAM Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000001433 193.0
HKD1_k127_3485928_5 Ferric uptake regulator family K03711 - - 0.00000000000000000000001763 105.0
HKD1_k127_349436_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 420.0
HKD1_k127_349436_1 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000005317 244.0
HKD1_k127_349436_2 Hsp20/alpha crystallin family - - - 0.000000000000000000000000000006856 123.0
HKD1_k127_349436_3 KR domain K00059 - 1.1.1.100 0.0000000000001108 72.0
HKD1_k127_350449_0 Non-ribosomal peptide synthetase modules and related - - - 1.647e-240 773.0
HKD1_k127_350449_1 amino acid activation for nonribosomal peptide biosynthetic process K00574,K02364,K04780,K19103 - 2.1.1.79,6.3.2.14 7.626e-219 709.0
HKD1_k127_350449_10 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00002568 49.0
HKD1_k127_350449_2 PFAM type III restriction protein res subunit - - - 6.447e-213 679.0
HKD1_k127_350449_3 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 358.0
HKD1_k127_350449_4 Multicopper K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 361.0
HKD1_k127_350449_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000001787 196.0
HKD1_k127_350449_6 Protein involved in initiation of plasmid replication - - - 0.00000000000000000000000000005473 120.0
HKD1_k127_350449_7 Nitroreductase family - - - 0.0000000000001854 73.0
HKD1_k127_350449_8 - - - - 0.0000000003628 68.0
HKD1_k127_350449_9 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000002465 49.0
HKD1_k127_350812_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 9.574e-215 673.0
HKD1_k127_350812_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 605.0
HKD1_k127_350812_10 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000002257 166.0
HKD1_k127_350812_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000005234 159.0
HKD1_k127_350812_12 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000001674 163.0
HKD1_k127_350812_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000006226 144.0
HKD1_k127_350812_14 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000008956 130.0
HKD1_k127_350812_15 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000005024 99.0
HKD1_k127_350812_16 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000000001592 79.0
HKD1_k127_350812_2 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 579.0
HKD1_k127_350812_3 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 400.0
HKD1_k127_350812_4 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 393.0
HKD1_k127_350812_5 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 376.0
HKD1_k127_350812_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 360.0
HKD1_k127_350812_7 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 322.0
HKD1_k127_350812_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000009656 231.0
HKD1_k127_3517253_0 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 0.0 1077.0
HKD1_k127_3517253_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 7.624e-265 844.0
HKD1_k127_3517253_10 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 407.0
HKD1_k127_3517253_11 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 346.0
HKD1_k127_3517253_12 Catalyzes the release of L-lysine from LysW -gamma-L- lysine K05831 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 344.0
HKD1_k127_3517253_13 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 326.0
HKD1_k127_3517253_14 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 292.0
HKD1_k127_3517253_15 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007799 264.0
HKD1_k127_3517253_16 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000001937 238.0
HKD1_k127_3517253_17 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000002159 244.0
HKD1_k127_3517253_18 NAD binding K00058,K04496 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000001966 241.0
HKD1_k127_3517253_19 Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine K05830 - - 0.00000000000000000000000000000000000000000000000000000000000000001228 229.0
HKD1_k127_3517253_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 2.909e-240 752.0
HKD1_k127_3517253_20 coenzyme F420-1:gamma-L-glutamate ligase activity K19286 - 1.5.1.39 0.0000000000000000000000000000000000000000000000000000000002455 211.0
HKD1_k127_3517253_21 nucleotidyl transferase K07281 - 2.7.7.74 0.00000000000000000000000000000000000000000000000000009949 196.0
HKD1_k127_3517253_22 Transcriptional regulator K03724 - - 0.00000000000000000000000000000000000000000000000000567 185.0
HKD1_k127_3517253_23 Flavin reductase-like protein - - - 0.0000000000000000000000000000000000000000000001494 175.0
HKD1_k127_3517253_24 phosphatase activity K05967 - - 0.000000000000000000000000000000000000000009527 161.0
HKD1_k127_3517253_25 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000002645 155.0
HKD1_k127_3517253_26 Bacterial transcriptional repressor C-terminal K16137 - - 0.000000000000000000000000000000001612 136.0
HKD1_k127_3517253_27 regulation of translation K03530 - - 0.0000000000000000000000000000009888 123.0
HKD1_k127_3517253_28 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.000000000000000000000000007638 115.0
HKD1_k127_3517253_29 Glycine cleavage H-protein - - - 0.000000000000000000000001152 112.0
HKD1_k127_3517253_3 PFAM natural resistance-associated macrophage protein K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 596.0
HKD1_k127_3517253_30 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000001286 103.0
HKD1_k127_3517253_31 peroxiredoxin activity K02199 - - 0.0000000000000003878 81.0
HKD1_k127_3517253_32 Cytochrome c7 and related cytochrome c - - - 0.0000000000001293 75.0
HKD1_k127_3517253_34 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.0000000000009054 71.0
HKD1_k127_3517253_36 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.00000002256 58.0
HKD1_k127_3517253_37 PFAM transposase, IS4 family protein - - - 0.000003728 54.0
HKD1_k127_3517253_38 Tripartite tricarboxylate transporter TctB family - - - 0.00000837 55.0
HKD1_k127_3517253_4 MlrC C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 598.0
HKD1_k127_3517253_5 PFAM response regulator receiver K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 571.0
HKD1_k127_3517253_6 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 569.0
HKD1_k127_3517253_7 HAMP domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 477.0
HKD1_k127_3517253_8 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 465.0
HKD1_k127_3517253_9 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 464.0
HKD1_k127_3528209_0 Gram-negative-bacterium-type cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000004086 231.0
HKD1_k127_3528209_1 TPM domain - - - 0.00000000000000000000000000000000000004345 155.0
HKD1_k127_3528209_2 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000006891 147.0
HKD1_k127_3528209_3 Histidine kinase K17292 - - 0.00000000000000000000000001135 119.0
HKD1_k127_3528209_4 Diguanylate cyclase - - - 0.00000000000000000000003043 106.0
HKD1_k127_3529456_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0 1104.0
HKD1_k127_3529456_1 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 418.0
HKD1_k127_3529456_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 398.0
HKD1_k127_3529456_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 377.0
HKD1_k127_3529456_4 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 382.0
HKD1_k127_3529456_5 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 354.0
HKD1_k127_3529456_6 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000003095 150.0
HKD1_k127_3529456_7 Cupin - - - 0.000000000000183 77.0
HKD1_k127_3529456_8 Domain present in phytochromes and cGMP-specific phosphodiesterases. K12266 - - 0.000000000119 63.0
HKD1_k127_3529832_0 Type III restriction enzyme res subunit - - - 4.091e-282 889.0
HKD1_k127_3529832_1 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007664 428.0
HKD1_k127_3529832_2 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000068 274.0
HKD1_k127_3529832_3 HicB family - - - 0.00000000000000000000000000000000000001356 151.0
HKD1_k127_3529832_4 PFAM Patatin - - - 0.000000000000000000000000000001943 130.0
HKD1_k127_3529832_5 HicB family - - - 0.00000000000000000214 87.0
HKD1_k127_3555642_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000001709 239.0
HKD1_k127_3555642_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000004001 193.0
HKD1_k127_3555642_2 - - - - 0.000000000000009319 84.0
HKD1_k127_3555889_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000001771 134.0
HKD1_k127_3562319_0 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 417.0
HKD1_k127_3562319_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 365.0
HKD1_k127_3562319_2 MlaD protein K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 342.0
HKD1_k127_3562319_3 ABC-type transport auxiliary lipoprotein component - - - 0.000000000000000000000000000000000000000000000000000000002074 207.0
HKD1_k127_3562319_4 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.00000000008108 62.0
HKD1_k127_3562620_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 609.0
HKD1_k127_3562620_1 Belongs to the D-glutamate cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 382.0
HKD1_k127_3562620_10 ABC-type branched-chain amino acid transport K01999 - - 0.000000000000000000000000000000000000000000207 164.0
HKD1_k127_3562620_11 Regulatory protein GntR HTH - - - 0.000000000000000000000000000000001635 138.0
HKD1_k127_3562620_12 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000007879 72.0
HKD1_k127_3562620_13 ThiS family K03636 - - 0.00006939 52.0
HKD1_k127_3562620_2 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 374.0
HKD1_k127_3562620_3 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 374.0
HKD1_k127_3562620_4 Protein of unknown function DUF111 K06898,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 353.0
HKD1_k127_3562620_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 324.0
HKD1_k127_3562620_6 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 328.0
HKD1_k127_3562620_7 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 294.0
HKD1_k127_3562620_8 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 298.0
HKD1_k127_3562620_9 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000003423 198.0
HKD1_k127_3577484_0 Transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 576.0
HKD1_k127_3577484_1 DNA invertase Pin - - - 0.0000000000000000000000000001601 119.0
HKD1_k127_3577484_2 PFAM Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000152 50.0
HKD1_k127_3593080_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 440.0
HKD1_k127_3593080_1 Zn_pept - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 334.0
HKD1_k127_3599270_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 1.454e-194 618.0
HKD1_k127_3599270_1 PFAM Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 411.0
HKD1_k127_3599270_2 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 383.0
HKD1_k127_3599270_3 Malate/L-lactate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
HKD1_k127_3599270_4 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002073 240.0
HKD1_k127_3599270_5 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000003439 183.0
HKD1_k127_3615071_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001526 256.0
HKD1_k127_3615071_1 alcohol dehydrogenase K00001,K00008 - 1.1.1.1,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000002769 252.0
HKD1_k127_3615071_2 Psort location CytoplasmicMembrane, score 10.00 K07793 - - 0.000000000000000000000000000000000000000000000000000000000009153 213.0
HKD1_k127_3615071_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000003317 86.0
HKD1_k127_3615071_4 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000004836 67.0
HKD1_k127_3682226_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0 1038.0
HKD1_k127_3682226_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.051e-218 708.0
HKD1_k127_3682226_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 372.0
HKD1_k127_3682226_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 347.0
HKD1_k127_3682226_4 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 334.0
HKD1_k127_3682226_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000005807 141.0
HKD1_k127_3682226_6 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000002345 85.0
HKD1_k127_3682226_7 Transposase IS200 like K07491 - - 0.000000001941 58.0
HKD1_k127_3689872_0 spore coat K01790 - 5.1.3.13 0.000000000000000000006683 96.0
HKD1_k127_3689872_1 PFAM Na dependent nucleoside transporter K03317 - - 0.00000000000000000006856 89.0
HKD1_k127_3726848_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1287.0
HKD1_k127_3726848_1 - - - - 2.988e-233 744.0
HKD1_k127_3726848_10 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 336.0
HKD1_k127_3726848_11 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 333.0
HKD1_k127_3726848_12 Ferric uptake regulator family K03711,K09825 - - 0.00000000000000000000000000000000001114 142.0
HKD1_k127_3726848_13 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000002706 122.0
HKD1_k127_3726848_14 PFAM regulatory protein ArsR K03892 - - 0.0000003625 52.0
HKD1_k127_3726848_2 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 599.0
HKD1_k127_3726848_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 441.0
HKD1_k127_3726848_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 455.0
HKD1_k127_3726848_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 439.0
HKD1_k127_3726848_6 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 429.0
HKD1_k127_3726848_7 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 379.0
HKD1_k127_3726848_8 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 378.0
HKD1_k127_3726848_9 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 366.0
HKD1_k127_3736813_0 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 2.407e-257 812.0
HKD1_k127_3736813_1 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 452.0
HKD1_k127_3736813_2 PFAM ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 457.0
HKD1_k127_3736813_3 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000002477 220.0
HKD1_k127_3736813_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000007711 219.0
HKD1_k127_3736813_5 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000246 164.0
HKD1_k127_3736813_6 Gram-negative-bacterium-type cell wall biogenesis - - - 0.000000000000000000000000000000000000006599 156.0
HKD1_k127_3736813_7 mechanosensitive ion channel - - - 0.0001659 51.0
HKD1_k127_374091_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 581.0
HKD1_k127_374091_1 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 414.0
HKD1_k127_374091_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 316.0
HKD1_k127_374091_3 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000001151 240.0
HKD1_k127_374091_4 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000001037 187.0
HKD1_k127_375385_0 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000002869 230.0
HKD1_k127_375385_1 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000005868 236.0
HKD1_k127_375385_2 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.0000000000000000000000000000000000000000007361 173.0
HKD1_k127_3755072_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 2.122e-237 741.0
HKD1_k127_3755072_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.37e-196 621.0
HKD1_k127_3755072_2 PFAM Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 454.0
HKD1_k127_3755072_3 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 367.0
HKD1_k127_3755072_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 354.0
HKD1_k127_3755072_5 Alcohol dehydrogenase GroES-like domain K00004,K00060 - 1.1.1.103,1.1.1.303,1.1.1.4 0.000000000000000000000000000002415 121.0
HKD1_k127_378626_0 LuxR family transcriptional regulator K03556 - - 1.62e-253 810.0
HKD1_k127_378626_1 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000001898 186.0
HKD1_k127_3797671_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 456.0
HKD1_k127_3797671_1 Putative methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 288.0
HKD1_k127_3797671_2 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004606 266.0
HKD1_k127_3797671_3 Putative methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002335 245.0
HKD1_k127_3797671_4 DinB family - - - 0.0000000000000000000000000000000000000000000000000000003103 197.0
HKD1_k127_3797671_5 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000000000000000001243 188.0
HKD1_k127_3797671_6 - - - - 0.0000000000000000000000000000000000000000000000001623 188.0
HKD1_k127_3797671_7 GAF domain - - - 0.0000000000000000000000000000000000004632 147.0
HKD1_k127_3797671_8 - - - - 0.0000000000000000000000000000128 130.0
HKD1_k127_3797671_9 - - - - 0.00000000000000000004888 95.0
HKD1_k127_3844504_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 8.933e-234 754.0
HKD1_k127_3844504_1 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 463.0
HKD1_k127_3844504_2 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 308.0
HKD1_k127_3844504_3 PFAM transport-associated - - - 0.00000000000000000000000000000000000000000000000000000000003835 220.0
HKD1_k127_3844504_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000003089 219.0
HKD1_k127_3844504_5 Competence-damaged protein - - - 0.0000000000000000000000000000000000000000000000000000007485 197.0
HKD1_k127_3844504_6 protein homooligomerization - - - 0.000000000000000000003624 100.0
HKD1_k127_3844504_7 regulation of response to stimulus K01406,K13730 - 3.4.24.40 0.00000000000000006028 95.0
HKD1_k127_3844504_8 Cupin domain - - - 0.0000000000003606 74.0
HKD1_k127_3897018_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 385.0
HKD1_k127_3897018_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 289.0
HKD1_k127_3897018_2 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.000000000000000000000000000000000000000000000000001388 188.0
HKD1_k127_3897018_3 - - - - 0.0000000000000004758 79.0
HKD1_k127_3897018_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000005352 53.0
HKD1_k127_3913541_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 1.169e-196 638.0
HKD1_k127_3913541_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 421.0
HKD1_k127_3913541_10 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000000001627 124.0
HKD1_k127_3913541_12 Psort location Cytoplasmic, score - - - 0.000952 47.0
HKD1_k127_3913541_2 'Xanthine and CO dehydrogenases maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 356.0
HKD1_k127_3913541_3 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 321.0
HKD1_k127_3913541_4 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003044 285.0
HKD1_k127_3913541_5 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020,K19711 - 1.1.1.31,1.1.1.387 0.00000000000000000000000000000000000000000000000000000000004316 216.0
HKD1_k127_3913541_6 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000000000121 212.0
HKD1_k127_3913541_7 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000002684 196.0
HKD1_k127_3913541_8 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000335 183.0
HKD1_k127_3913541_9 cellulose binding - - - 0.0000000000000000000000000000000000000001102 162.0
HKD1_k127_3913843_0 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005743 278.0
HKD1_k127_3913843_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000001871 157.0
HKD1_k127_3913843_2 regulation of DNA-templated transcription, elongation - - - 0.0000000009147 65.0
HKD1_k127_3915602_0 Transglycosylase K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 3.344e-277 873.0
HKD1_k127_3915602_1 Endoribonuclease that initiates mRNA decay K05802,K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 550.0
HKD1_k127_3915602_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 482.0
HKD1_k127_3915602_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 445.0
HKD1_k127_3915602_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 329.0
HKD1_k127_3915602_5 YmdB-like protein K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 321.0
HKD1_k127_3915602_6 O-methyltransferase - - - 0.0000000000000000000000000000002057 132.0
HKD1_k127_3915602_7 - - - - 0.000000000001281 69.0
HKD1_k127_3950751_0 mannitol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 552.0
HKD1_k127_3950751_1 carbohydrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 474.0
HKD1_k127_3950751_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000006638 194.0
HKD1_k127_3950751_11 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.000000000000000000000000000000000000000000267 165.0
HKD1_k127_3950751_12 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit - - - 0.000000000000000000000000000000000000001247 149.0
HKD1_k127_3950751_13 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.00000000000000000000000000001665 123.0
HKD1_k127_3950751_14 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000009311 117.0
HKD1_k127_3950751_15 SPTR CopG domain protein DNA-binding domain protein - - - 0.000000000001521 71.0
HKD1_k127_3950751_16 - - - - 0.000000000006596 71.0
HKD1_k127_3950751_17 Membrane - - - 0.000002715 56.0
HKD1_k127_3950751_19 - - - - 0.0008146 43.0
HKD1_k127_3950751_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 469.0
HKD1_k127_3950751_3 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 437.0
HKD1_k127_3950751_4 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 414.0
HKD1_k127_3950751_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 406.0
HKD1_k127_3950751_6 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 408.0
HKD1_k127_3950751_7 N-acyl-D-amino acid deacylase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 368.0
HKD1_k127_3950751_8 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 328.0
HKD1_k127_3950751_9 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 307.0
HKD1_k127_3960396_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652,K03852 - 2.2.1.6,2.3.3.15 1.04e-241 770.0
HKD1_k127_3960396_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 471.0
HKD1_k127_3960396_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 408.0
HKD1_k127_3960396_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 379.0
HKD1_k127_3960396_4 TIGRFAM tripartite ATP-independent periplasmic transporter solute receptor, DctP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 343.0
HKD1_k127_3960396_5 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 325.0
HKD1_k127_3960396_6 serine-type endopeptidase activity K08372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001235 257.0
HKD1_k127_3960396_7 KR domain - - - 0.000000002665 65.0
HKD1_k127_3960396_8 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component K21394 - - 0.00009212 50.0
HKD1_k127_3983017_0 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 299.0
HKD1_k127_3983017_1 Yqey-like protein K09117 - - 0.00000000000000000000000000000000005287 139.0
HKD1_k127_3983017_2 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000006143 100.0
HKD1_k127_4018370_0 Aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 473.0
HKD1_k127_4018370_1 PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 292.0
HKD1_k127_4018370_2 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000001363 217.0
HKD1_k127_4018370_4 epimerase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000009422 78.0
HKD1_k127_4020389_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 451.0
HKD1_k127_4020389_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 381.0
HKD1_k127_4020389_2 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.0000000000000000000000000000000000000000000000007828 180.0
HKD1_k127_4020389_3 Fusaric acid resistance protein-like - - - 0.000000000000000000000000000000000000000000004544 181.0
HKD1_k127_4031170_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.234e-311 976.0
HKD1_k127_4031170_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 531.0
HKD1_k127_4031170_10 Leucine-rich repeats, typical (most populated) subfamily K19613 - - 0.0003371 47.0
HKD1_k127_4031170_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 525.0
HKD1_k127_4031170_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 305.0
HKD1_k127_4031170_4 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004544 274.0
HKD1_k127_4031170_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000004467 217.0
HKD1_k127_4031170_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000006948 209.0
HKD1_k127_4031170_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000319 173.0
HKD1_k127_4031170_8 RecX family K03565 - - 0.0000000000000000002549 94.0
HKD1_k127_4031170_9 family 5 K15580 - - 0.0000000000000001453 92.0
HKD1_k127_4040791_0 TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1312.0
HKD1_k127_4040791_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 515.0
HKD1_k127_4040791_2 Domain of unknown function (DUF1956) - - - 0.000000000000000000000000000000000000000000000000000000000000000006098 231.0
HKD1_k127_4060991_0 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 399.0
HKD1_k127_4060991_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 316.0
HKD1_k127_4060991_2 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 239.0
HKD1_k127_4060991_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000005333 170.0
HKD1_k127_4063904_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.743e-232 736.0
HKD1_k127_4063904_1 Cytidylyltransferase K00983 - 2.7.7.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 365.0
HKD1_k127_4063904_2 Belongs to the aldehyde dehydrogenase family K00128,K00135,K22187 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000197 198.0
HKD1_k127_4070765_0 Heavy metal translocating P-type atpase K01533,K01534,K17686 - 3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 387.0
HKD1_k127_4070765_1 DinB superfamily - - - 0.00000000000000000516 91.0
HKD1_k127_4070765_2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000009681 74.0
HKD1_k127_4074560_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 385.0
HKD1_k127_4074560_1 catalyzes the formation of indole and pyruvate from tryptophan K01667 - 4.1.99.1 0.0000000000000000000000000446 108.0
HKD1_k127_4074560_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000481 102.0
HKD1_k127_4081181_0 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000001102 194.0
HKD1_k127_4081181_1 phosphinothricin N-acetyltransferase activity K03823,K03892,K05793 - 2.3.1.183 0.000000000000000000000000000000000000000000000000005013 184.0
HKD1_k127_4081181_2 chelatase, subunit ChlI K07391 - - 0.000001435 54.0
HKD1_k127_4087770_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1196.0
HKD1_k127_4087770_1 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0 1165.0
HKD1_k127_4087770_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 417.0
HKD1_k127_4087770_3 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 415.0
HKD1_k127_4087770_4 - - - - 0.0000000000000000003791 90.0
HKD1_k127_4087770_5 Protein of unknown function (DUF2283) - - - 0.00000000000000004837 83.0
HKD1_k127_4094428_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 469.0
HKD1_k127_4094428_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000006367 194.0
HKD1_k127_4094428_3 histidine kinase, HAMP - - - 0.000000000000000000000000000000000000000000001337 186.0
HKD1_k127_4094428_4 Mechanosensitive ion channel - - - 0.000000000006971 75.0
HKD1_k127_4121480_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 546.0
HKD1_k127_4121480_1 Phosphonate ABC transporter K02044 - - 0.0000000000000000000000000000000000000000000000003011 191.0
HKD1_k127_4121480_2 ParB-like nuclease domain K03497 - - 0.000000000000000000000000006285 115.0
HKD1_k127_4121480_3 Glutaredoxin-like domain (DUF836) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000002002 70.0
HKD1_k127_4124314_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 493.0
HKD1_k127_4124314_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000007876 122.0
HKD1_k127_4134972_0 Elongator protein 3, MiaB family, Radical SAM - - - 2.4e-322 1007.0
HKD1_k127_4134972_1 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 3.174e-211 676.0
HKD1_k127_4134972_10 PUA domain K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 422.0
HKD1_k127_4134972_11 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 398.0
HKD1_k127_4134972_12 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 387.0
HKD1_k127_4134972_13 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 343.0
HKD1_k127_4134972_14 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 291.0
HKD1_k127_4134972_15 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000009147 212.0
HKD1_k127_4134972_16 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000006702 185.0
HKD1_k127_4134972_17 Competence protein - - - 0.0000000000000000000000000000000000005434 149.0
HKD1_k127_4134972_18 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K00969,K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 0.000000000000000000000000000000000000659 146.0
HKD1_k127_4134972_19 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000004786 135.0
HKD1_k127_4134972_2 Aldehyde dehydrogenase family K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 553.0
HKD1_k127_4134972_20 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000000000000001148 125.0
HKD1_k127_4134972_21 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000004745 127.0
HKD1_k127_4134972_22 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000006594 118.0
HKD1_k127_4134972_23 Two component regulator propeller - - - 0.00000000000000001358 96.0
HKD1_k127_4134972_24 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.00000000007775 68.0
HKD1_k127_4134972_26 COG2885 Outer membrane protein and related peptidoglycan-associated - - - 0.00001562 55.0
HKD1_k127_4134972_3 phosphorelay signal transduction system K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 546.0
HKD1_k127_4134972_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 533.0
HKD1_k127_4134972_5 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 501.0
HKD1_k127_4134972_6 PFAM Aminotransferase class I and II K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 474.0
HKD1_k127_4134972_7 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 473.0
HKD1_k127_4134972_8 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 477.0
HKD1_k127_4134972_9 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 434.0
HKD1_k127_4160158_0 AcrB/AcrD/AcrF family K03296,K19594 - - 0.0 1471.0
HKD1_k127_4160158_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K19595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 354.0
HKD1_k127_4160158_2 phosphinothricin N-acetyltransferase activity K03823,K18816 - 2.3.1.183,2.3.1.82 0.0003134 46.0
HKD1_k127_4168501_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 1.23e-292 906.0
HKD1_k127_4168501_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.857e-215 682.0
HKD1_k127_4168501_10 Binding-protein-dependent transport system inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 426.0
HKD1_k127_4168501_11 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 413.0
HKD1_k127_4168501_12 Transglycosylase SLT domain K07114,K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 425.0
HKD1_k127_4168501_13 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 388.0
HKD1_k127_4168501_14 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 404.0
HKD1_k127_4168501_15 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 394.0
HKD1_k127_4168501_16 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 354.0
HKD1_k127_4168501_17 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 345.0
HKD1_k127_4168501_18 Queuosine biosynthesis protein K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 352.0
HKD1_k127_4168501_19 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 293.0
HKD1_k127_4168501_2 cellulose binding - - - 5.733e-213 666.0
HKD1_k127_4168501_20 Phosphomethylpyrimidine kinase K00868,K00941,K03147,K21219 GO:0008150,GO:0040007 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7,4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009668 273.0
HKD1_k127_4168501_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006014 254.0
HKD1_k127_4168501_22 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000002983 228.0
HKD1_k127_4168501_23 PFAM Stage II sporulation K06381 - - 0.00000000000000000000000000000000000000000000000000000000000117 227.0
HKD1_k127_4168501_24 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000002314 176.0
HKD1_k127_4168501_25 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000001267 186.0
HKD1_k127_4168501_26 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000001105 173.0
HKD1_k127_4168501_27 YCII-related domain - - - 0.00000000000000000000000000000000000000000005365 161.0
HKD1_k127_4168501_28 Glycerol-3-phosphate responsive antiterminator K02443 - - 0.00000000000000000000000000000000000000000008943 167.0
HKD1_k127_4168501_29 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000001334 149.0
HKD1_k127_4168501_3 Bacterial extracellular solute-binding protein K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 605.0
HKD1_k127_4168501_30 - - - - 0.00000000000000000000000000000000000409 142.0
HKD1_k127_4168501_31 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000001151 139.0
HKD1_k127_4168501_32 protein SCO1 SenC K07152 - - 0.000000000000000000000000001619 123.0
HKD1_k127_4168501_33 Preprotein translocase subunit K03210 - - 0.000000000000000000000000002475 118.0
HKD1_k127_4168501_34 Protein of unknown function (DUF2905) - - - 0.000000000000000000000009275 103.0
HKD1_k127_4168501_35 - - - - 0.0000000000001493 74.0
HKD1_k127_4168501_36 methyltransferase - - - 0.0000000000004664 78.0
HKD1_k127_4168501_37 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000001249 57.0
HKD1_k127_4168501_38 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 0.000877 44.0
HKD1_k127_4168501_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 601.0
HKD1_k127_4168501_5 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 524.0
HKD1_k127_4168501_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 512.0
HKD1_k127_4168501_7 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 467.0
HKD1_k127_4168501_8 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 473.0
HKD1_k127_4168501_9 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 441.0
HKD1_k127_4177429_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K18331 - 1.12.1.3 0.0 1142.0
HKD1_k127_4177429_1 FMN binding - - - 1.245e-240 753.0
HKD1_k127_4177429_2 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003974 262.0
HKD1_k127_4182309_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 305.0
HKD1_k127_4182309_1 methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000008342 277.0
HKD1_k127_4182309_2 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000003537 216.0
HKD1_k127_4182309_3 Winged helix DNA-binding domain - - - 0.00000000000000000000000005274 114.0
HKD1_k127_4182309_4 PFAM Radical SAM domain protein - - - 0.0002224 46.0
HKD1_k127_4188983_0 Uncharacterized protein family (UPF0051) K09014 - - 1.54e-274 849.0
HKD1_k127_4188983_1 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 593.0
HKD1_k127_4188983_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000006349 178.0
HKD1_k127_4188983_11 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000003038 112.0
HKD1_k127_4188983_12 phosphorelay signal transduction system - - - 0.0000000000000000000002543 101.0
HKD1_k127_4188983_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 588.0
HKD1_k127_4188983_3 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 501.0
HKD1_k127_4188983_4 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 455.0
HKD1_k127_4188983_5 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 374.0
HKD1_k127_4188983_6 COGs COG2912 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005041 261.0
HKD1_k127_4188983_7 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000004869 257.0
HKD1_k127_4188983_8 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000002379 223.0
HKD1_k127_4188983_9 KR domain K12420 - - 0.0000000000000000000000000000000000000000000000000001086 195.0
HKD1_k127_4192197_0 Thiamine pyrophosphate enzyme, central domain K01608 - 4.1.1.47 3.1e-225 712.0
HKD1_k127_4192197_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 614.0
HKD1_k127_4192197_10 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004289 274.0
HKD1_k127_4192197_11 transporter solute receptor, DctP family - - - 0.0000000000000000000000000000000000000000000000000000000000000001097 230.0
HKD1_k127_4192197_12 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000004907 210.0
HKD1_k127_4192197_13 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000001266 196.0
HKD1_k127_4192197_14 ABC-type sugar transport system periplasmic component K02027 - - 0.000000000001485 72.0
HKD1_k127_4192197_15 ThiS family K03636 - - 0.00000000004264 67.0
HKD1_k127_4192197_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 395.0
HKD1_k127_4192197_3 Belongs to the PdxA family K22024 - 1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 413.0
HKD1_k127_4192197_4 H( )-stimulated, divalent metal cation uptake system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 352.0
HKD1_k127_4192197_5 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 315.0
HKD1_k127_4192197_6 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 300.0
HKD1_k127_4192197_7 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009457 292.0
HKD1_k127_4192197_8 Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation K01305 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008270,GO:0008798,GO:0016787,GO:0019538,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004028 288.0
HKD1_k127_4192197_9 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001084 285.0
HKD1_k127_419692_0 PFAM Transketolase K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 395.0
HKD1_k127_419692_1 Alcohol dehydrogenase zinc-binding domain protein K13953,K18382 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 357.0
HKD1_k127_419692_10 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001782 280.0
HKD1_k127_419692_11 Coenzyme A transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001158 278.0
HKD1_k127_419692_12 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000007685 279.0
HKD1_k127_419692_13 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000207 271.0
HKD1_k127_419692_14 ABC-type sugar transport system, permease component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000224 267.0
HKD1_k127_419692_15 Coenzyme A transferase K01039 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000004529 266.0
HKD1_k127_419692_16 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005253 265.0
HKD1_k127_419692_17 mandelate racemase muconate lactonizing K01684,K08323 - 4.2.1.6,4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000392 263.0
HKD1_k127_419692_18 Branched-chain amino acid transport system / permease component K02057,K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002098 257.0
HKD1_k127_419692_19 ATPases associated with a variety of cellular activities K10545 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000007853 254.0
HKD1_k127_419692_2 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 345.0
HKD1_k127_419692_20 Periplasmic binding protein-like domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002347 249.0
HKD1_k127_419692_21 Coenzyme A transferase K01039,K01040 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000001097 238.0
HKD1_k127_419692_22 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.000000000000000000000000000000000000000000000000000000000000001528 230.0
HKD1_k127_419692_23 Binding-protein-dependent transport system inner membrane component K02025,K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000328 228.0
HKD1_k127_419692_24 dehydratase - - - 0.00000000000000000000000000000000000000000000000000001161 202.0
HKD1_k127_419692_25 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000004088 195.0
HKD1_k127_419692_26 - - - - 0.0000000000000000000000001756 110.0
HKD1_k127_419692_27 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000004677 99.0
HKD1_k127_419692_28 Helix-turn-helix domain, rpiR family - - - 0.000000000000000001075 87.0
HKD1_k127_419692_29 Tripartite ATP-independent periplasmic transporter, DctQ - - - 0.0000000000000000642 89.0
HKD1_k127_419692_3 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 349.0
HKD1_k127_419692_30 Bacterial extracellular solute-binding protein K02027,K17329 - - 0.00000000000009377 84.0
HKD1_k127_419692_31 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000004274 76.0
HKD1_k127_419692_32 CoA-transferase family III - - - 0.0000000001456 72.0
HKD1_k127_419692_33 Uncharacterised protein family UPF0066 - - - 0.000000214 55.0
HKD1_k127_419692_34 Uncharacterised protein family UPF0066 - - - 0.00005047 47.0
HKD1_k127_419692_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 336.0
HKD1_k127_419692_5 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 324.0
HKD1_k127_419692_6 Acyl-protein synthetase, LuxE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 321.0
HKD1_k127_419692_7 CoA-transferase family III K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 320.0
HKD1_k127_419692_8 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 329.0
HKD1_k127_419692_9 Coenzyme A transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007007 289.0
HKD1_k127_4222085_0 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 458.0
HKD1_k127_4222085_1 isomerase activity K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000007692 248.0
HKD1_k127_4222085_2 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000001008 205.0
HKD1_k127_4222085_3 serine-type endopeptidase activity K04772,K08372 - - 0.0000000000000000000000000000001253 136.0
HKD1_k127_4222085_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.0000000000000000005197 94.0
HKD1_k127_4231183_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 613.0
HKD1_k127_4231183_1 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 509.0
HKD1_k127_4231183_2 COG0520 Selenocysteine lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 461.0
HKD1_k127_4231183_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 343.0
HKD1_k127_4231183_4 (ABC) transporter, permease K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006118 271.0
HKD1_k127_4231183_5 MgtE intracellular N domain K02000,K05847 - 3.6.3.32 0.0000000000000000000000000000002438 133.0
HKD1_k127_4237691_0 elongation factor G K02355 - - 3.005e-276 870.0
HKD1_k127_4237691_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 537.0
HKD1_k127_4237691_10 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 286.0
HKD1_k127_4237691_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003421 274.0
HKD1_k127_4237691_12 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000008595 238.0
HKD1_k127_4237691_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001471 240.0
HKD1_k127_4237691_14 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002812 224.0
HKD1_k127_4237691_15 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000006665 203.0
HKD1_k127_4237691_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000004127 200.0
HKD1_k127_4237691_17 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000003508 203.0
HKD1_k127_4237691_18 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000009918 196.0
HKD1_k127_4237691_19 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000006872 195.0
HKD1_k127_4237691_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 520.0
HKD1_k127_4237691_20 Ribosomal protein L17 K02879,K16193 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001627 179.0
HKD1_k127_4237691_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000008927 177.0
HKD1_k127_4237691_22 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000841 177.0
HKD1_k127_4237691_23 Involved in the binding of tRNA to the ribosomes K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000003007 169.0
HKD1_k127_4237691_24 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000007893 158.0
HKD1_k127_4237691_25 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000005905 165.0
HKD1_k127_4237691_26 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000000000338 146.0
HKD1_k127_4237691_27 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000004632 140.0
HKD1_k127_4237691_28 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000006604 137.0
HKD1_k127_4237691_29 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000003991 127.0
HKD1_k127_4237691_3 Participates in both transcription termination and antitermination K02600 GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 525.0
HKD1_k127_4237691_30 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000002632 114.0
HKD1_k127_4237691_31 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000008838 103.0
HKD1_k127_4237691_32 Ribosomal protein L36 K02919 - - 0.000000000000002312 76.0
HKD1_k127_4237691_33 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000003702 66.0
HKD1_k127_4237691_34 Protein of unknown function (DUF448) K07742 - - 0.00000000006168 72.0
HKD1_k127_4237691_35 Ribosomal protein L30 K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000001319 71.0
HKD1_k127_4237691_36 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000007837 63.0
HKD1_k127_4237691_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008663 421.0
HKD1_k127_4237691_5 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 422.0
HKD1_k127_4237691_6 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 335.0
HKD1_k127_4237691_7 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 331.0
HKD1_k127_4237691_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 309.0
HKD1_k127_4237691_9 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 296.0
HKD1_k127_4240272_0 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000006897 89.0
HKD1_k127_424282_0 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000000000000002119 201.0
HKD1_k127_424282_1 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000003522 144.0
HKD1_k127_424282_2 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000276 130.0
HKD1_k127_4254292_0 - - - - 0.00000000000000000000000000000000000000004929 164.0
HKD1_k127_4254292_1 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000884 158.0
HKD1_k127_4254292_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000001771 94.0
HKD1_k127_4258541_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 504.0
HKD1_k127_4258541_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 409.0
HKD1_k127_4258541_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 376.0
HKD1_k127_4258541_3 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004273 253.0
HKD1_k127_4258541_4 cheY-homologous receiver domain K07658 - - 0.0000000000000000000000003578 109.0
HKD1_k127_4271040_0 ATPase (P-type) K01535 - 3.6.3.6 2.088e-250 800.0
HKD1_k127_4271040_1 Thiamine pyrophosphate enzyme, central domain - - - 2.083e-219 693.0
HKD1_k127_4271040_10 Belongs to the BI1 family K06890,K19416 - - 0.0000000000000000000000000000000000000000000000000000000001301 213.0
HKD1_k127_4271040_11 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000007743 173.0
HKD1_k127_4271040_12 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000002971 166.0
HKD1_k127_4271040_13 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000006379 139.0
HKD1_k127_4271040_15 Predicted membrane protein (DUF2231) - - - 0.000000000000009918 79.0
HKD1_k127_4271040_17 - - - - 0.000000001879 64.0
HKD1_k127_4271040_2 4Fe-4S dicluster domain K00184 - - 5.03e-219 694.0
HKD1_k127_4271040_3 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 597.0
HKD1_k127_4271040_4 PFAM ABC transporter K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 585.0
HKD1_k127_4271040_5 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 503.0
HKD1_k127_4271040_6 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 406.0
HKD1_k127_4271040_7 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008798 386.0
HKD1_k127_4271040_8 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 398.0
HKD1_k127_4271040_9 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 306.0
HKD1_k127_4278899_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000006134 162.0
HKD1_k127_4278899_1 Tetratricopeptide repeat - - - 0.0000000001117 73.0
HKD1_k127_4280072_0 major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 492.0
HKD1_k127_4280072_1 MmgE PrpD family protein - - - 0.0000000000000000000001715 100.0
HKD1_k127_4280072_2 PAP2 superfamily C-terminal - - - 0.000000000000009145 76.0
HKD1_k127_4283340_0 Orn/Lys/Arg decarboxylase, N-terminal domain K01581 - 4.1.1.17 1.392e-309 956.0
HKD1_k127_4283340_1 Amino acid permease K03756,K03759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 376.0
HKD1_k127_4284343_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 505.0
HKD1_k127_4312757_0 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 2.55e-263 833.0
HKD1_k127_4312757_1 PFAM ABC transporter related K01995,K01998 - - 1.861e-199 638.0
HKD1_k127_4312757_10 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 415.0
HKD1_k127_4312757_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 374.0
HKD1_k127_4312757_12 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 317.0
HKD1_k127_4312757_13 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007752 269.0
HKD1_k127_4312757_14 GAF domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004596 284.0
HKD1_k127_4312757_15 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000001107 265.0
HKD1_k127_4312757_16 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006057 277.0
HKD1_k127_4312757_17 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000001471 258.0
HKD1_k127_4312757_18 Binding-protein-dependent transport system inner membrane component K02026,K10190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007914 265.0
HKD1_k127_4312757_19 ATPases associated with a variety of cellular activities K01995,K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000001148 235.0
HKD1_k127_4312757_2 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 569.0
HKD1_k127_4312757_20 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0034641,GO:0043170,GO:0043737,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000001346 239.0
HKD1_k127_4312757_21 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000007548 226.0
HKD1_k127_4312757_22 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000001205 197.0
HKD1_k127_4312757_23 Methyltransferase domain K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000004634 195.0
HKD1_k127_4312757_24 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000000007281 186.0
HKD1_k127_4312757_25 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000001305 181.0
HKD1_k127_4312757_26 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000001334 177.0
HKD1_k127_4312757_27 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000001514 177.0
HKD1_k127_4312757_28 Histidine kinase - - - 0.0000000000000000000000000000000000000000000008008 186.0
HKD1_k127_4312757_29 Histidine kinase - - - 0.000000000000000000000000000000000000004142 161.0
HKD1_k127_4312757_3 PFAM Radical SAM K22226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009717 492.0
HKD1_k127_4312757_30 heme binding - - - 0.0000000000000000000000000000000000004554 151.0
HKD1_k127_4312757_31 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000006571 152.0
HKD1_k127_4312757_32 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000008012 118.0
HKD1_k127_4312757_34 PFAM Rhodanese domain protein - - - 0.000000000000000000006024 96.0
HKD1_k127_4312757_36 Sec-independent protein translocase protein TatA K03116 - - 0.000000000000000002704 88.0
HKD1_k127_4312757_37 regulation of response to stimulus K01406,K13730 - 3.4.24.40 0.00000000000000003904 92.0
HKD1_k127_4312757_38 DinB superfamily - - - 0.0000000000000001645 88.0
HKD1_k127_4312757_39 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.0000000000000002242 89.0
HKD1_k127_4312757_4 PFAM beta-lactamase domain protein K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 489.0
HKD1_k127_4312757_40 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000001072 77.0
HKD1_k127_4312757_41 Type II secretion system protein B - - - 0.0000000002287 70.0
HKD1_k127_4312757_42 Rhodanese Homology Domain - - - 0.000000291 52.0
HKD1_k127_4312757_43 Fibronectin, type III domain - - - 0.0009931 50.0
HKD1_k127_4312757_5 Amidase, hydantoinase carbamoylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 475.0
HKD1_k127_4312757_6 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 467.0
HKD1_k127_4312757_7 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 421.0
HKD1_k127_4312757_8 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 425.0
HKD1_k127_4312757_9 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671,K22345 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 413.0
HKD1_k127_4322959_1 Hemerythrin HHE cation binding domain K16276 - - 0.00000000000009099 80.0
HKD1_k127_4323193_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 1.063e-255 799.0
HKD1_k127_4323193_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 454.0
HKD1_k127_4323193_10 PFAM Glycosyl transferase, group 1 - - - 0.0009201 45.0
HKD1_k127_4323193_2 Evidence 2b Function of strongly homologous gene K02446,K11532 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 414.0
HKD1_k127_4323193_3 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 338.0
HKD1_k127_4323193_4 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 310.0
HKD1_k127_4323193_5 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000111 268.0
HKD1_k127_4323193_6 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000000000000001539 226.0
HKD1_k127_4323193_7 Two component transcriptional regulator, winged helix family K07658,K07668 - - 0.0000000000000000000005569 104.0
HKD1_k127_4323193_8 response regulator receiver - - - 0.000000000000001059 87.0
HKD1_k127_4323193_9 PFAM Pentapeptide repeats (8 copies) - - - 0.0000004717 55.0
HKD1_k127_4356390_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1216.0
HKD1_k127_4356390_1 ATPase BadF BadG BcrA BcrD type - - - 0.0 1025.0
HKD1_k127_4356390_10 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 421.0
HKD1_k127_4356390_11 Ferrous iron transport B domain protein K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 424.0
HKD1_k127_4356390_12 Chalcone and stilbene synthases, C-terminal domain K16424 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 405.0
HKD1_k127_4356390_13 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 403.0
HKD1_k127_4356390_14 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 355.0
HKD1_k127_4356390_15 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 349.0
HKD1_k127_4356390_16 Hydrogenase expression formation protein (HypE) K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 331.0
HKD1_k127_4356390_17 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 340.0
HKD1_k127_4356390_18 drug transmembrane transporter activity K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 318.0
HKD1_k127_4356390_19 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 314.0
HKD1_k127_4356390_2 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 3.953e-295 927.0
HKD1_k127_4356390_20 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 298.0
HKD1_k127_4356390_21 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000148 287.0
HKD1_k127_4356390_22 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005087 263.0
HKD1_k127_4356390_23 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003718 261.0
HKD1_k127_4356390_24 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004803 259.0
HKD1_k127_4356390_25 TIGRFAM geranylgeranyl reductase K21401 - 1.3.99.38 0.000000000000000000000000000000000000000000000000000000000000000000002674 255.0
HKD1_k127_4356390_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000001957 236.0
HKD1_k127_4356390_27 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000003593 240.0
HKD1_k127_4356390_28 geranylgeranyl reductase activity - - - 0.000000000000000000000000000000000000000000000000000000002916 214.0
HKD1_k127_4356390_29 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000009581 195.0
HKD1_k127_4356390_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 606.0
HKD1_k127_4356390_30 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000003285 196.0
HKD1_k127_4356390_31 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000004183 181.0
HKD1_k127_4356390_32 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000165 178.0
HKD1_k127_4356390_33 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000003115 158.0
HKD1_k127_4356390_34 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000001542 147.0
HKD1_k127_4356390_35 Thioredoxin-like - - - 0.000000000000000000000000000000000001204 147.0
HKD1_k127_4356390_36 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000003661 151.0
HKD1_k127_4356390_37 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000155 141.0
HKD1_k127_4356390_38 Peptidase S46 - - - 0.000000000000000000000000000000001694 147.0
HKD1_k127_4356390_39 PFAM Iron permease FTR1 - - - 0.000000000000000000000000000000009199 147.0
HKD1_k127_4356390_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 597.0
HKD1_k127_4356390_40 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000000008915 130.0
HKD1_k127_4356390_41 SMART Signal transduction response regulator, receiver domain - - - 0.000000000000000000000000000000272 134.0
HKD1_k127_4356390_42 Evidence 5 No homology to any previously reported sequences K09005 - - 0.000000000000000000001735 108.0
HKD1_k127_4356390_43 TonB C terminal K03832 - - 0.000000000000000000004304 105.0
HKD1_k127_4356390_44 peptidyl-tyrosine sulfation - - - 0.0000000000000000005476 95.0
HKD1_k127_4356390_45 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - GO:0000003,GO:0000226,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005802,GO:0005829,GO:0006950,GO:0006970,GO:0006996,GO:0007010,GO:0007017,GO:0007275,GO:0008150,GO:0008360,GO:0009628,GO:0009651,GO:0009653,GO:0009791,GO:0009826,GO:0009888,GO:0009908,GO:0009965,GO:0009987,GO:0010016,GO:0010026,GO:0010090,GO:0010091,GO:0010154,GO:0010482,GO:0010494,GO:0010769,GO:0012505,GO:0016043,GO:0016049,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022613,GO:0022618,GO:0030154,GO:0030856,GO:0031128,GO:0031129,GO:0031984,GO:0032501,GO:0032502,GO:0032989,GO:0032991,GO:0034063,GO:0034622,GO:0035770,GO:0036464,GO:0040007,GO:0042802,GO:0042803,GO:0042814,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045604,GO:0045682,GO:0046983,GO:0048366,GO:0048367,GO:0048437,GO:0048444,GO:0048468,GO:0048530,GO:0048589,GO:0048608,GO:0048731,GO:0048827,GO:0048831,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051239,GO:0051302,GO:0060284,GO:0060560,GO:0061458,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071826,GO:0071840,GO:0090558,GO:0090567,GO:0090626,GO:0090696,GO:0090697,GO:0090698,GO:0098791,GO:0099402,GO:1905392,GO:1990904,GO:2000024,GO:2000026,GO:2000039 - 0.000000000428 68.0
HKD1_k127_4356390_46 PFAM Xylose isomerase domain-containing protein TIM barrel - - - 0.000002004 59.0
HKD1_k127_4356390_47 TIGRFAM TonB K03832 - - 0.00001215 56.0
HKD1_k127_4356390_5 Trypsin K08070,K08372 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 488.0
HKD1_k127_4356390_6 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 490.0
HKD1_k127_4356390_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 444.0
HKD1_k127_4356390_8 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 449.0
HKD1_k127_4356390_9 Glycosyl transferases group 1 K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 422.0
HKD1_k127_4362541_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 530.0
HKD1_k127_4362541_1 Belongs to the 3-oxoacid CoA-transferase family K01026 - 2.8.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 469.0
HKD1_k127_4362541_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 416.0
HKD1_k127_4362541_3 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 343.0
HKD1_k127_4362541_4 proline dipeptidase activity K18829 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 334.0
HKD1_k127_4362541_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000429 144.0
HKD1_k127_4362541_6 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.0000000000005245 71.0
HKD1_k127_4376302_0 Mannitol dehydrogenase K00009,K00041 - 1.1.1.17,1.1.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 312.0
HKD1_k127_4376302_1 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000004404 236.0
HKD1_k127_4376302_2 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000001182 138.0
HKD1_k127_4376302_3 DNA polymerase beta domain protein region K07075 - - 0.00000000000000000000001557 109.0
HKD1_k127_4376302_4 Protein of unknown function (DUF2442) - - - 0.000000007863 62.0
HKD1_k127_4376302_5 Putative addiction module component - - - 0.000000008631 57.0
HKD1_k127_437635_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.852e-221 694.0
HKD1_k127_437635_1 thiamine transport K02011 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 601.0
HKD1_k127_437635_10 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.000000000000000000000000000000000001147 142.0
HKD1_k127_437635_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 489.0
HKD1_k127_437635_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 438.0
HKD1_k127_437635_4 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 394.0
HKD1_k127_437635_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 379.0
HKD1_k127_437635_6 iron ion homeostasis K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 355.0
HKD1_k127_437635_7 Oxidoreductase family, NAD-binding Rossmann fold K18106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 328.0
HKD1_k127_437635_8 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 315.0
HKD1_k127_437635_9 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000237 205.0
HKD1_k127_4382411_0 Heat shock 70 kDa protein K04043 - - 0.0 1029.0
HKD1_k127_4382411_1 transferase activity, transferring glycosyl groups - - - 2.627e-217 689.0
HKD1_k127_4382411_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000006505 210.0
HKD1_k127_4382411_11 Histidine kinase K02668,K07709,K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000499 219.0
HKD1_k127_4382411_12 response regulator receiver K07714,K10943 - - 0.00000000000000000000000000000000000000000000000000003235 193.0
HKD1_k127_4382411_13 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000001133 174.0
HKD1_k127_4382411_14 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000002148 160.0
HKD1_k127_4382411_15 YGGT family K02221 - - 0.000000000000000000000000000000001146 133.0
HKD1_k127_4382411_16 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000001199 132.0
HKD1_k127_4382411_18 PFAM DivIVA family protein K04074 - - 0.000000000000000000001057 101.0
HKD1_k127_4382411_19 Belongs to the UPF0235 family K09131 - - 0.00000000000000009141 89.0
HKD1_k127_4382411_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 454.0
HKD1_k127_4382411_3 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 447.0
HKD1_k127_4382411_4 Transglycosylase SLT domain K08307,K12204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 402.0
HKD1_k127_4382411_5 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 378.0
HKD1_k127_4382411_6 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 371.0
HKD1_k127_4382411_7 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 309.0
HKD1_k127_4382411_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001817 281.0
HKD1_k127_4382411_9 Glycosyltransferase Family 4 K19002 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 0.0000000000000000000000000000000000000000000000000000000000000000000000000002696 270.0
HKD1_k127_4385393_0 MacB-like periplasmic core domain K02004 - - 1.618e-201 656.0
HKD1_k127_4385393_1 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 608.0
HKD1_k127_4385393_2 PrpF protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 520.0
HKD1_k127_4385393_3 Alpha amylase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 460.0
HKD1_k127_4385393_4 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 420.0
HKD1_k127_4385393_5 ABC transporter K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003212 261.0
HKD1_k127_4385393_6 Glycogen debranching enzyme - - - 0.00000000000000000184 98.0
HKD1_k127_4385393_7 protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000004218 84.0
HKD1_k127_4399404_0 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000005426 231.0
HKD1_k127_4399404_1 - - - - 0.0000000000000000000000000000000000000001733 153.0
HKD1_k127_4399404_2 response to heat K03668 - - 0.000000000000000000009217 99.0
HKD1_k127_4399404_3 Malate/L-lactate dehydrogenase - - - 0.00000000002173 66.0
HKD1_k127_4417514_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 533.0
HKD1_k127_4417514_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 496.0
HKD1_k127_4417514_2 Domains HisKA, HATPase_c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000358 287.0
HKD1_k127_4417514_3 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002742 232.0
HKD1_k127_4417514_4 response regulator receiver - - - 0.0000000000000000000000000309 114.0
HKD1_k127_4417514_5 PFAM EamA-like transporter family - - - 0.00000000000000003835 92.0
HKD1_k127_4417514_6 GGDEF domain K01768,K02488,K07676,K10715,K20976 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3,2.7.7.65,4.6.1.1 0.00000000000000206 81.0
HKD1_k127_4417514_7 Cartilage oligomeric matrix protein K04659,K16857 GO:0001501,GO:0001968,GO:0002020,GO:0003416,GO:0003417,GO:0003674,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005912,GO:0005924,GO:0005927,GO:0006950,GO:0007155,GO:0007275,GO:0007517,GO:0007610,GO:0008150,GO:0008201,GO:0008289,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010941,GO:0012505,GO:0016043,GO:0016203,GO:0016528,GO:0016529,GO:0019842,GO:0019899,GO:0022610,GO:0030054,GO:0030055,GO:0030198,GO:0031012,GO:0032501,GO:0032502,GO:0032991,GO:0033554,GO:0033555,GO:0033627,GO:0034103,GO:0034976,GO:0035265,GO:0036094,GO:0040007,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043394,GO:0043395,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046872,GO:0048265,GO:0048266,GO:0048513,GO:0048519,GO:0048523,GO:0048589,GO:0048705,GO:0048731,GO:0048736,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051216,GO:0051239,GO:0051716,GO:0060173,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060538,GO:0060548,GO:0061061,GO:0061448,GO:0062023,GO:0065007,GO:0070161,GO:0071840,GO:0097159,GO:0097367,GO:0098868,GO:1901681 - 0.000000308 53.0
HKD1_k127_4418597_0 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 400.0
HKD1_k127_4418597_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 336.0
HKD1_k127_4418597_10 Dystroglycan-type cadherin-like domains. - - - 0.0000000000009024 79.0
HKD1_k127_4418597_11 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K00057 - 1.1.1.94 0.0000002493 54.0
HKD1_k127_4418597_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002393 287.0
HKD1_k127_4418597_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000189 258.0
HKD1_k127_4418597_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000007454 246.0
HKD1_k127_4418597_5 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000003683 228.0
HKD1_k127_4418597_6 PIN domain - - - 0.000000000000000000000000007834 114.0
HKD1_k127_4418597_7 cheY-homologous receiver domain - - - 0.000000000000000000000005166 109.0
HKD1_k127_4418597_8 Mycolic acid cyclopropane synthetase - - - 0.000000000000000006168 83.0
HKD1_k127_4418597_9 Amidohydrolase K07045 - - 0.0000000000000001725 90.0
HKD1_k127_4432643_0 PFAM transposase, mutator K07493 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 346.0
HKD1_k127_4432643_1 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000007866 224.0
HKD1_k127_4476572_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 458.0
HKD1_k127_4476572_1 Glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001425 285.0
HKD1_k127_4476572_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000002513 193.0
HKD1_k127_4476572_3 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000001189 198.0
HKD1_k127_4482805_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 486.0
HKD1_k127_4482805_1 lactate/malate dehydrogenase, alpha/beta C-terminal domain K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000002079 209.0
HKD1_k127_4489034_0 Coenzyme A transferase K01026 - 2.8.3.1 3.403e-194 618.0
HKD1_k127_4489034_1 Evidence 4 Homologs of previously reported genes of K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 301.0
HKD1_k127_4489034_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000007179 228.0
HKD1_k127_4489034_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000001507 222.0
HKD1_k127_4489034_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000004076 175.0
HKD1_k127_4489034_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000001343 92.0
HKD1_k127_4491032_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 458.0
HKD1_k127_4491032_1 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000006773 190.0
HKD1_k127_4491032_2 energy transducer activity K03646,K03832 - - 0.0008517 51.0
HKD1_k127_4499297_0 transmembrane transporter activity - - - 0.0 1668.0
HKD1_k127_4499297_1 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 387.0
HKD1_k127_4499297_2 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 334.0
HKD1_k127_4499297_3 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001288 261.0
HKD1_k127_4499297_4 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000008403 237.0
HKD1_k127_4499297_5 WHG domain - - - 0.00000006802 61.0
HKD1_k127_4499297_6 - - - - 0.0000001062 60.0
HKD1_k127_4502759_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381 - 1.2.4.1,1.2.4.4 0.0 1016.0
HKD1_k127_4502759_1 P-loop ATPase protein family K06958,K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 5.133e-196 623.0
HKD1_k127_4502759_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 586.0
HKD1_k127_4502759_3 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 355.0
HKD1_k127_4502759_4 Peptidase dimerisation domain K01439,K05831 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 329.0
HKD1_k127_4502759_5 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001483 241.0
HKD1_k127_4502759_6 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000005055 217.0
HKD1_k127_4502759_7 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000003154 98.0
HKD1_k127_4502759_8 CopG antitoxin of type II toxin-antitoxin system - - - 0.00000001109 64.0
HKD1_k127_4516597_0 XFP C-terminal domain K01621 - 4.1.2.22,4.1.2.9 0.0 1471.0
HKD1_k127_4516597_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1339.0
HKD1_k127_4516597_10 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.00000000008108 62.0
HKD1_k127_4516597_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 1.432e-263 821.0
HKD1_k127_4516597_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 5.229e-229 720.0
HKD1_k127_4516597_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 567.0
HKD1_k127_4516597_5 Belongs to the transketolase family K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 531.0
HKD1_k127_4516597_6 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008966 268.0
HKD1_k127_4516597_7 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000003132 203.0
HKD1_k127_4516597_8 Phasin protein - - - 0.000000000000000000000000000000000001525 143.0
HKD1_k127_4516597_9 fructose-bisphosphate aldolase K01623 - 4.1.2.13 0.0000000000003085 70.0
HKD1_k127_452238_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 466.0
HKD1_k127_452238_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 414.0
HKD1_k127_452238_10 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000004905 70.0
HKD1_k127_452238_11 Domain of unknown function (DUF4160) - - - 0.00000000007954 71.0
HKD1_k127_452238_12 Protein of unknown function (DUF2442) - - - 0.0000001468 62.0
HKD1_k127_452238_2 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 399.0
HKD1_k127_452238_3 restriction endonuclease K07448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 386.0
HKD1_k127_452238_4 transcription activator K03707 - 3.5.99.2 0.000000000000000000000000000000000000000000000000000000000000002621 226.0
HKD1_k127_452238_5 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000000000000000000000000000000000000005262 225.0
HKD1_k127_452238_6 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000004823 220.0
HKD1_k127_452238_7 addiction module antidote protein HigA K21498 - - 0.0000000000000000000000000000000000000000000000004125 176.0
HKD1_k127_452238_8 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000000000000000001188 171.0
HKD1_k127_452238_9 2Fe-2S -binding domain protein K18029 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016725,GO:0019439,GO:0044237,GO:0044248,GO:0055114 1.17.2.1 0.000000000000000000000000000000000000000000002064 169.0
HKD1_k127_4527304_0 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000000003638 225.0
HKD1_k127_4527304_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000004055 140.0
HKD1_k127_4527304_2 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000004407 133.0
HKD1_k127_4527314_0 Oxidoreductase molybdopterin binding domain K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 486.0
HKD1_k127_4527314_1 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 481.0
HKD1_k127_4527314_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000001224 214.0
HKD1_k127_4527314_3 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000000000000000000003132 217.0
HKD1_k127_4527314_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000141 134.0
HKD1_k127_4527314_5 DGC domain - - - 0.00000001307 60.0
HKD1_k127_453763_0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 593.0
HKD1_k127_453763_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007131 564.0
HKD1_k127_453763_10 Belongs to the cysteine synthase cystathionine beta- synthase family K01738,K01912 - 2.5.1.47,6.2.1.30 0.0000000000000000000000000001987 115.0
HKD1_k127_453763_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000006773 123.0
HKD1_k127_453763_12 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000005095 98.0
HKD1_k127_453763_13 heme-binding sites - - - 0.0000000000000001991 94.0
HKD1_k127_453763_14 cyclopropane-fatty-acyl-phospholipid synthase K00574,K03466 - 2.1.1.79 0.0000000000000008731 88.0
HKD1_k127_453763_15 Major facilitator Superfamily - - - 0.000885 46.0
HKD1_k127_453763_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 471.0
HKD1_k127_453763_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 360.0
HKD1_k127_453763_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 359.0
HKD1_k127_453763_5 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 273.0
HKD1_k127_453763_6 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000000008147 207.0
HKD1_k127_453763_7 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000000000000000000000000000000000003595 176.0
HKD1_k127_453763_8 DoxX K15977 - - 0.00000000000000000000000000000000000516 142.0
HKD1_k127_453763_9 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000005428 126.0
HKD1_k127_4543201_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 3.717e-203 658.0
HKD1_k127_4543201_1 ABC transporter substrate-binding protein K02027,K10232 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 448.0
HKD1_k127_4543201_2 Major Facilitator Superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 424.0
HKD1_k127_4543201_3 formate C-acetyltransferase glycine radical K00656,K20038 - 2.3.1.54,4.3.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 392.0
HKD1_k127_4543201_4 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 300.0
HKD1_k127_4543201_5 transport systems K02025,K10233 - - 0.00000000000000000000000000000000000000003222 156.0
HKD1_k127_4544600_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 335.0
HKD1_k127_4544600_1 Domain of unknown function DUF11 - - - 0.0000000000000000000000000001613 133.0
HKD1_k127_4544600_2 Domain of unknown function DUF11 - - - 0.0000000000000000000000002199 123.0
HKD1_k127_4544600_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.00000000000000000007025 90.0
HKD1_k127_4544600_4 Lactonase, 7-bladed beta-propeller K08884,K12132 - 2.7.11.1 0.000001061 62.0
HKD1_k127_4561495_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006529 264.0
HKD1_k127_4561495_1 cell redox homeostasis - - - 0.000000000000000007667 87.0
HKD1_k127_4562624_0 Prolyl oligopeptidase family K01303 - 3.4.19.1 2.136e-257 809.0
HKD1_k127_4567815_0 Acyl-CoA synthetase (NDP forming) K09181 - - 3.485e-244 772.0
HKD1_k127_4567815_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 472.0
HKD1_k127_4567815_10 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000001954 181.0
HKD1_k127_4567815_11 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000002016 192.0
HKD1_k127_4567815_12 Universal stress protein family - - - 0.000000000000000000000000000000000000008364 150.0
HKD1_k127_4567815_13 protein tyrosine kinase activity - - - 0.0000000000000000000000000000000000001337 152.0
HKD1_k127_4567815_14 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000001163 133.0
HKD1_k127_4567815_15 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000006352 106.0
HKD1_k127_4567815_16 PFAM sigma-54 factor interaction domain-containing protein K07714 - - 0.000000000000000000007544 97.0
HKD1_k127_4567815_17 - K00176,K07138 - 1.2.7.3 0.0000000000000006994 80.0
HKD1_k127_4567815_2 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 460.0
HKD1_k127_4567815_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 421.0
HKD1_k127_4567815_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 362.0
HKD1_k127_4567815_5 PFAM thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 349.0
HKD1_k127_4567815_6 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 319.0
HKD1_k127_4567815_7 thiosulfate sulfurtransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 295.0
HKD1_k127_4567815_8 DRTGG domain K13788 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001543 279.0
HKD1_k127_4567815_9 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000007144 208.0
HKD1_k127_4593334_0 C4-dicarboxylate ABC transporter permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 473.0
HKD1_k127_4593334_1 transporter solute receptor, DctP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 308.0
HKD1_k127_4593334_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000003037 242.0
HKD1_k127_4593334_3 Domain of unknown function (DUF4178) - - - 0.00000000000000001205 98.0
HKD1_k127_4593334_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000008378 87.0
HKD1_k127_4593334_5 FemAB family - - - 0.000000000000001349 87.0
HKD1_k127_461075_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.065e-299 932.0
HKD1_k127_461075_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 1.433e-266 827.0
HKD1_k127_461075_10 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001238 273.0
HKD1_k127_461075_11 succinyl-diaminopimelate desuccinylase activity - - - 0.00000000000000000000000000000000000000000000000000000003186 220.0
HKD1_k127_461075_12 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000003422 183.0
HKD1_k127_461075_13 Putative regulatory protein - - - 0.0000000000000000000000000000000000000000003128 168.0
HKD1_k127_461075_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000004047 156.0
HKD1_k127_461075_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000006002 139.0
HKD1_k127_461075_16 Polymer-forming cytoskeletal - - - 0.0000000000000000000000007973 113.0
HKD1_k127_461075_17 tetratricopeptide repeat - - - 0.00000000000000000000004412 117.0
HKD1_k127_461075_18 DinB superfamily - - - 0.000000000000000000002688 100.0
HKD1_k127_461075_19 SMART Chromosomal replication initiator DnaA domain - - - 0.0000000000000000008888 93.0
HKD1_k127_461075_2 proton-transporting ATP synthase activity, rotational mechanism K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 9.605e-221 692.0
HKD1_k127_461075_20 Transcriptional regulator - - - 0.000000000002472 78.0
HKD1_k127_461075_22 hmm pf04305 - - - 0.00002461 49.0
HKD1_k127_461075_23 - - - - 0.0008041 47.0
HKD1_k127_461075_3 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 509.0
HKD1_k127_461075_4 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 527.0
HKD1_k127_461075_5 ATPase associated with K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 389.0
HKD1_k127_461075_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 348.0
HKD1_k127_461075_7 oligoendopeptidase F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 305.0
HKD1_k127_461075_8 oxidoreductase activity K07114,K16257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001174 307.0
HKD1_k127_461075_9 Von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001431 269.0
HKD1_k127_4626009_0 PFAM aminotransferase class-III K01845,K21585 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006083,GO:0006091,GO:0006113,GO:0006520,GO:0006553,GO:0006554,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0015980,GO:0016054,GO:0016740,GO:0016769,GO:0016999,GO:0017144,GO:0019475,GO:0019477,GO:0019665,GO:0019666,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0036094,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046440,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.111,5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 460.0
HKD1_k127_4626009_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 422.0
HKD1_k127_4626009_2 Acetohydroxy acid isomeroreductase, NADPH-binding domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000001518 215.0
HKD1_k127_4626009_3 Endoribonuclease L-PSP K09021 - - 0.00000000000000000000000002258 115.0
HKD1_k127_4626009_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000003583 63.0
HKD1_k127_4630903_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1679.0
HKD1_k127_4630903_1 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 589.0
HKD1_k127_4630903_10 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000005084 265.0
HKD1_k127_4630903_11 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000007942 222.0
HKD1_k127_4630903_12 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000000000008672 193.0
HKD1_k127_4630903_13 Uridine 5-monophosphate K13421 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0016036,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0050896,GO:0051716,GO:0071496 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000002947 185.0
HKD1_k127_4630903_14 Nitroreductase family - - - 0.00000000000000000000000000000000001719 145.0
HKD1_k127_4630903_15 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K04764 - - 0.0000000000000000000000000000001634 127.0
HKD1_k127_4630903_16 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000006561 111.0
HKD1_k127_4630903_17 - - - - 0.000000000000000000006683 96.0
HKD1_k127_4630903_19 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000004447 82.0
HKD1_k127_4630903_2 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 567.0
HKD1_k127_4630903_20 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000001926 94.0
HKD1_k127_4630903_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 572.0
HKD1_k127_4630903_4 protein histidine kinase activity K07315,K07641,K10819,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 522.0
HKD1_k127_4630903_5 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 473.0
HKD1_k127_4630903_6 Catalyzes the conversion of dihydroorotate to orotate K00226,K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2,1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 430.0
HKD1_k127_4630903_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 385.0
HKD1_k127_4630903_8 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 302.0
HKD1_k127_4630903_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003507 284.0
HKD1_k127_4650897_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 348.0
HKD1_k127_4650897_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000004619 127.0
HKD1_k127_4686496_0 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000007013 256.0
HKD1_k127_4686496_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000707 236.0
HKD1_k127_4686496_2 - - - - 0.000000000000000001319 97.0
HKD1_k127_4694922_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.925e-214 676.0
HKD1_k127_4694922_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009213 268.0
HKD1_k127_471297_0 TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1043.0
HKD1_k127_471297_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000005345 151.0
HKD1_k127_471297_2 - - - - 0.000000002846 68.0
HKD1_k127_4734119_0 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 308.0
HKD1_k127_4734119_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000001046 153.0
HKD1_k127_4734119_2 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000001984 119.0
HKD1_k127_4734119_3 spore germination K00442,K03605,K04656,K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.00000000000000000000004061 108.0
HKD1_k127_4734119_4 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436,K14126 - 1.12.1.2,1.8.98.5 0.0000000000000007307 77.0
HKD1_k127_4739862_0 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 499.0
HKD1_k127_4740603_0 extracellular alpha-helical protein K06894 - - 0.0 1284.0
HKD1_k127_4740603_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 1.742e-201 659.0
HKD1_k127_4740603_2 KR domain K00059,K21883 - 1.1.1.100,1.1.1.401 0.0000000000000000000000000000000000000000000000000001508 199.0
HKD1_k127_4740603_3 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000003069 110.0
HKD1_k127_47409_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1330.0
HKD1_k127_47409_1 Pfam:DUF162 - - - 7.999e-211 668.0
HKD1_k127_47409_10 SEC-C Motif Domain Protein - - - 0.000000000000000000000000007887 128.0
HKD1_k127_47409_11 deoxyhypusine monooxygenase activity K03070,K05385 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000001082 95.0
HKD1_k127_47409_12 - - - - 0.0000000000000001258 84.0
HKD1_k127_47409_13 methyltransferase activity - - - 0.000000003583 63.0
HKD1_k127_47409_14 Tripartite tricarboxylate transporter TctB family - - - 0.00004449 52.0
HKD1_k127_47409_2 Psort location CytoplasmicMembrane, score K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 608.0
HKD1_k127_47409_3 H( )-stimulated, divalent metal cation uptake system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 493.0
HKD1_k127_47409_4 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 370.0
HKD1_k127_47409_5 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 359.0
HKD1_k127_47409_6 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 298.0
HKD1_k127_47409_7 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000019 247.0
HKD1_k127_47409_8 - - - - 0.0000000000000000000000000000000006592 132.0
HKD1_k127_47409_9 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000003919 116.0
HKD1_k127_4752112_0 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 1.787e-259 811.0
HKD1_k127_4752112_1 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 303.0
HKD1_k127_4752112_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000005044 240.0
HKD1_k127_4752112_3 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000005668 111.0
HKD1_k127_4752112_4 - - - - 0.0000000000000000002434 93.0
HKD1_k127_4752112_5 ABC transporter K02068 - - 0.0000000000000001281 85.0
HKD1_k127_4752112_6 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0001568 48.0
HKD1_k127_4755979_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006043 258.0
HKD1_k127_4755979_1 metal-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000258 213.0
HKD1_k127_4755979_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000002533 176.0
HKD1_k127_4755979_3 DinB superfamily K07552 - - 0.00000000000000000000000000000000000000000000006548 174.0
HKD1_k127_4755979_4 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000002949 167.0
HKD1_k127_4755979_5 Membrane - - - 0.00000000000000000154 91.0
HKD1_k127_4770743_0 PFAM transposase IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 331.0
HKD1_k127_4770743_1 sptr a7nhu5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 296.0
HKD1_k127_4798383_0 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 426.0
HKD1_k127_4798383_1 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 428.0
HKD1_k127_4798383_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 326.0
HKD1_k127_4798383_3 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 308.0
HKD1_k127_4798383_4 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004336 283.0
HKD1_k127_4798383_5 protein containing SIS (Sugar ISomerase) phosphosugar binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
HKD1_k127_4798383_6 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000003855 151.0
HKD1_k127_4798383_7 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000027 147.0
HKD1_k127_4798383_8 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000002129 83.0
HKD1_k127_482443_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000004165 220.0
HKD1_k127_482443_1 Protein of unknown function (DUF418) K07148 - - 0.000000000000000000000000000000000008338 143.0
HKD1_k127_482443_2 GYD domain - - - 0.00000000000000000000000000004869 119.0
HKD1_k127_4928913_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 364.0
HKD1_k127_4928913_1 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 316.0
HKD1_k127_4928913_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000006305 244.0
HKD1_k127_4928913_3 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001041 220.0
HKD1_k127_4928913_4 PIN domain - - - 0.00000000000000000000000002374 113.0
HKD1_k127_4928913_5 toxin-antitoxin pair type II binding - - - 0.000001136 53.0
HKD1_k127_4933780_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.012e-275 857.0
HKD1_k127_4933780_1 carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 554.0
HKD1_k127_4933780_2 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000009355 181.0
HKD1_k127_4933780_3 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000000001881 132.0
HKD1_k127_4933780_4 - - - - 0.000000000000000000000000001557 122.0
HKD1_k127_4933780_5 Sodium/hydrogen exchanger family - - - 0.0000000002287 63.0
HKD1_k127_4956482_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 357.0
HKD1_k127_4956482_1 peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 365.0
HKD1_k127_4963203_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 4.571e-222 706.0
HKD1_k127_4963203_1 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 494.0
HKD1_k127_4963203_10 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000002515 180.0
HKD1_k127_4963203_11 PFAM Peptidase family M28 - - - 0.000000000000000000000000000000000003102 154.0
HKD1_k127_4963203_12 Domain of unknown function (DUF4203) - - - 0.00000000000000000008105 95.0
HKD1_k127_4963203_13 diguanylate cyclase - - - 0.00000000000000001039 94.0
HKD1_k127_4963203_2 Phosphoadenosine phosphosulfate reductase K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 422.0
HKD1_k127_4963203_3 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 359.0
HKD1_k127_4963203_4 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 358.0
HKD1_k127_4963203_5 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 295.0
HKD1_k127_4963203_6 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 290.0
HKD1_k127_4963203_7 Function Code 14.4 Transport and Binding Proteins Carbohydrates, organic alcohols, and acids K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006772 253.0
HKD1_k127_4963203_8 CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000007533 239.0
HKD1_k127_4963203_9 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000007918 217.0
HKD1_k127_4980246_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 2.584e-196 619.0
HKD1_k127_4980246_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, His Kinase A (phosphoacceptor) domain, Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 462.0
HKD1_k127_4980246_2 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 392.0
HKD1_k127_4980246_3 response regulator K07774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000193 275.0
HKD1_k127_4980246_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000406 211.0
HKD1_k127_4982848_0 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 475.0
HKD1_k127_4982848_1 Transposase K07483 - - 0.000000000000000000000000000000000000002075 148.0
HKD1_k127_4982848_2 IS66 Orf2 like protein K07484 - - 0.000000000002031 69.0
HKD1_k127_4986369_0 iron dependent repressor K02003,K02565,K15545 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 418.0
HKD1_k127_5017209_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.141e-229 719.0
HKD1_k127_5017209_1 PFAM IstB-like ATP binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 317.0
HKD1_k127_5017209_2 Integrase core domain - - - 0.000000000000000000000000000000000000000002244 160.0
HKD1_k127_5030809_0 DEAD DEAH box K06877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 535.0
HKD1_k127_5030809_1 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 428.0
HKD1_k127_5030809_10 PFAM Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000002543 227.0
HKD1_k127_5030809_11 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000002871 212.0
HKD1_k127_5030809_12 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000001369 192.0
HKD1_k127_5030809_13 COG0500 SAM-dependent methyltransferases K17462 - - 0.00000000000000000000000000000000000000000000000003823 192.0
HKD1_k127_5030809_14 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000006029 160.0
HKD1_k127_5030809_15 COG1943 Transposase and inactivated derivatives K07491 - - 0.000000000000000000000000000000000002137 149.0
HKD1_k127_5030809_16 PFAM methyltransferase - - - 0.00000000000000000000000000000526 131.0
HKD1_k127_5030809_17 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000003918 94.0
HKD1_k127_5030809_18 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000399 85.0
HKD1_k127_5030809_19 Psort location Cytoplasmic, score - - - 0.0000000000002312 73.0
HKD1_k127_5030809_2 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 409.0
HKD1_k127_5030809_20 nucleotidyltransferase activity - - - 0.000000000001211 78.0
HKD1_k127_5030809_21 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000001507 74.0
HKD1_k127_5030809_22 - - - - 0.00000000003386 68.0
HKD1_k127_5030809_3 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 364.0
HKD1_k127_5030809_4 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004632 289.0
HKD1_k127_5030809_5 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000543 284.0
HKD1_k127_5030809_6 Sugar ABC transporter permease K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008583 247.0
HKD1_k127_5030809_7 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000003525 240.0
HKD1_k127_5030809_8 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000004654 228.0
HKD1_k127_5030809_9 Alginate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000002605 237.0
HKD1_k127_5032625_0 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 435.0
HKD1_k127_5032625_1 methylenetetrahydrofolate reductase (NAD(P)H) activity K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 423.0
HKD1_k127_5032625_10 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 316.0
HKD1_k127_5032625_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 312.0
HKD1_k127_5032625_12 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001241 301.0
HKD1_k127_5032625_13 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 254.0
HKD1_k127_5032625_14 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001889 230.0
HKD1_k127_5032625_15 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000009375 228.0
HKD1_k127_5032625_16 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000001446 218.0
HKD1_k127_5032625_17 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000004692 199.0
HKD1_k127_5032625_18 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000009825 181.0
HKD1_k127_5032625_19 Lysine exporter LysO - - - 0.00000000000000000000000000000000000000000000000483 179.0
HKD1_k127_5032625_2 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 419.0
HKD1_k127_5032625_20 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000000000000009248 160.0
HKD1_k127_5032625_21 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657,K07658,K18941 - - 0.0000000000000000001308 102.0
HKD1_k127_5032625_22 ATP-dependent Clp protease adaptor protein ClpS - - - 0.00000000000008637 76.0
HKD1_k127_5032625_23 Lysine exporter LysO - - - 0.0000001996 56.0
HKD1_k127_5032625_3 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 391.0
HKD1_k127_5032625_4 cell adhesion involved in biofilm formation K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 376.0
HKD1_k127_5032625_5 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 364.0
HKD1_k127_5032625_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 369.0
HKD1_k127_5032625_7 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 352.0
HKD1_k127_5032625_8 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 341.0
HKD1_k127_5032625_9 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 315.0
HKD1_k127_5038871_0 Belongs to the glutaminase family K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002503 261.0
HKD1_k127_5038871_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001945 256.0
HKD1_k127_5038871_2 PFAM Bile acid sodium symporter K03453 - - 0.0000000000000000000000000000000000000000004344 169.0
HKD1_k127_5038871_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0002478 46.0
HKD1_k127_5043958_0 Pyruvate phosphate dikinase PEP K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 580.0
HKD1_k127_5046311_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006527 338.0
HKD1_k127_5046311_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000005106 239.0
HKD1_k127_5046311_2 tryptophanase activity K01667 - 4.1.99.1 0.00000000000000000000000000000000005596 135.0
HKD1_k127_5046311_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.00000000000000004523 85.0
HKD1_k127_5046311_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000439 46.0
HKD1_k127_5054033_0 PFAM Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000002179 151.0
HKD1_k127_5054033_1 Phage capsid family - - - 0.00000000000000000000006363 112.0
HKD1_k127_5054033_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000004533 100.0
HKD1_k127_5054033_3 Helix-turn-helix domain - - - 0.00000004277 57.0
HKD1_k127_5054033_4 Belongs to the 'phage' integrase family - - - 0.0000005783 57.0
HKD1_k127_5057000_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 579.0
HKD1_k127_5057000_1 Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 542.0
HKD1_k127_5057000_10 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000007798 136.0
HKD1_k127_5057000_11 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000002381 119.0
HKD1_k127_5057000_12 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000001942 83.0
HKD1_k127_5057000_13 STAS domain - - - 0.00007285 51.0
HKD1_k127_5057000_2 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928,K03587,K15792 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.4.16.4,6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 543.0
HKD1_k127_5057000_3 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 459.0
HKD1_k127_5057000_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 309.0
HKD1_k127_5057000_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 304.0
HKD1_k127_5057000_6 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 296.0
HKD1_k127_5057000_7 Alpha/beta hydrolase family K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001991 263.0
HKD1_k127_5057000_8 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215,K03546 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000001086 208.0
HKD1_k127_5057000_9 MraZ protein, putative antitoxin-like K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000005529 132.0
HKD1_k127_5065325_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 576.0
HKD1_k127_5065325_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 461.0
HKD1_k127_5065325_2 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 435.0
HKD1_k127_5065325_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000002383 133.0
HKD1_k127_5065325_4 PFAM Tripartite tricarboxylate transporter TctB family K07794 - - 0.000001127 58.0
HKD1_k127_5065815_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 2.116e-204 651.0
HKD1_k127_5065815_1 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000004117 226.0
HKD1_k127_5065815_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000001433 192.0
HKD1_k127_5065815_3 Major Facilitator - - - 0.00000000000000000000002266 101.0
HKD1_k127_5070917_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 505.0
HKD1_k127_5070917_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 430.0
HKD1_k127_5082897_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 2.5e-323 1004.0
HKD1_k127_5082897_1 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 528.0
HKD1_k127_5082897_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 491.0
HKD1_k127_5082897_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001517 282.0
HKD1_k127_508754_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 338.0
HKD1_k127_508754_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003142 241.0
HKD1_k127_508754_2 molybdenum cofactor K03638,K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000007121 185.0
HKD1_k127_508754_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000001172 151.0
HKD1_k127_508754_4 PFAM asparagine synthase K06864 - - 0.0000000000000000007539 88.0
HKD1_k127_5113175_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1162.0
HKD1_k127_5113175_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 539.0
HKD1_k127_5113175_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 475.0
HKD1_k127_5113175_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001898 259.0
HKD1_k127_5113175_4 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0000000000000005025 91.0
HKD1_k127_5113322_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 556.0
HKD1_k127_5113322_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 432.0
HKD1_k127_5113322_2 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 387.0
HKD1_k127_5113322_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 332.0
HKD1_k127_5113322_4 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 325.0
HKD1_k127_5113322_5 S1/P1 Nuclease K05986 - 3.1.30.1 0.000000000000000000000702 99.0
HKD1_k127_5113322_6 S1 P1 nuclease - - - 0.000000000001544 71.0
HKD1_k127_5119803_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 524.0
HKD1_k127_5119803_1 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.00000000000000000000000000000000000000000000003448 173.0
HKD1_k127_5123032_0 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000615 178.0
HKD1_k127_5123032_1 Response regulator receiver domain - - - 0.000000000000000000001387 99.0
HKD1_k127_512503_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K14090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 549.0
HKD1_k127_512503_1 quinone binding K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 390.0
HKD1_k127_512503_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008193 248.0
HKD1_k127_512503_3 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000001564 205.0
HKD1_k127_512503_4 4Fe-4S binding domain K14091 - - 0.00000000000000000000000000000000000000000000007789 186.0
HKD1_k127_512503_5 Transcriptional modulator of MazE toxin, MazF K07171,K18841 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000141 169.0
HKD1_k127_512503_6 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000975 147.0
HKD1_k127_512503_7 PFAM SpoVT AbrB K07172 - - 0.000000000000000000000000002579 113.0
HKD1_k127_512503_8 spore germination K00442,K08315 - 3.4.23.51 0.000000000000000000000003784 109.0
HKD1_k127_5131147_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K02342,K04096,K12472 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 2.7.7.7,6.5.1.2 2.155e-300 933.0
HKD1_k127_5131147_1 Pyridoxal-phosphate dependent enzyme - - - 5.949e-208 654.0
HKD1_k127_5131147_10 Carbohydrate ABC transporter membrane protein 2, CUT1 family K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 324.0
HKD1_k127_5131147_11 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 289.0
HKD1_k127_5131147_12 alcohol dehydrogenase K00004,K00008 - 1.1.1.14,1.1.1.303,1.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000259 282.0
HKD1_k127_5131147_13 ABC-type sugar transport system periplasmic component K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000154 250.0
HKD1_k127_5131147_14 PFAM Alcohol dehydrogenase GroES-like K00004,K00008,K00060 - 1.1.1.103,1.1.1.14,1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000006135 234.0
HKD1_k127_5131147_15 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000003354 223.0
HKD1_k127_5131147_16 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000014 214.0
HKD1_k127_5131147_17 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.000000000000000000000000000000000000000000000000002304 191.0
HKD1_k127_5131147_18 Trap-type c4-dicarboxylate transport system, small permease component - - - 0.000000000000000000000000000000000000000000000112 175.0
HKD1_k127_5131147_19 HAD-hyrolase-like - - - 0.000000000000000000000000000000001185 140.0
HKD1_k127_5131147_2 M20 DapE family protein YgeY - - - 1.137e-199 629.0
HKD1_k127_5131147_20 PFAM Forkhead-associated protein - - - 0.0000000000000000000000008082 120.0
HKD1_k127_5131147_21 Hexapeptide repeat of succinyl-transferase - - - 0.000000007001 67.0
HKD1_k127_5131147_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 572.0
HKD1_k127_5131147_4 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 482.0
HKD1_k127_5131147_5 threonine synthase activity K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 450.0
HKD1_k127_5131147_6 PFAM carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 448.0
HKD1_k127_5131147_7 ABC-type sugar transport system periplasmic component K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 353.0
HKD1_k127_5131147_8 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 343.0
HKD1_k127_5131147_9 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 339.0
HKD1_k127_5138820_0 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.0 1041.0
HKD1_k127_5138820_1 COG0286 Type I restriction-modification system K03427 - 2.1.1.72 1.156e-258 805.0
HKD1_k127_5138820_2 Restriction endonuclease S K01154 - 3.1.21.3 0.000000000000000000000000000000001697 138.0
HKD1_k127_5138820_3 Protein of unknown function (DUF433) - - - 0.0000000000000000000007301 96.0
HKD1_k127_5138820_4 - - - - 0.0000000000000001981 84.0
HKD1_k127_5140957_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1292.0
HKD1_k127_5140957_1 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 352.0
HKD1_k127_5140957_2 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 344.0
HKD1_k127_5140957_3 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001206 253.0
HKD1_k127_5140957_4 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004561 250.0
HKD1_k127_5140957_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000001245 176.0
HKD1_k127_5140957_6 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000001151 163.0
HKD1_k127_5140957_7 Acyl-protein synthetase, LuxE - - - 0.00005644 45.0
HKD1_k127_5155601_0 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 400.0
HKD1_k127_5155601_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001988 280.0
HKD1_k127_5155601_2 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002222 230.0
HKD1_k127_5155601_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000001279 101.0
HKD1_k127_5158460_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 556.0
HKD1_k127_5161291_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 341.0
HKD1_k127_5161291_1 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 328.0
HKD1_k127_5161291_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000001876 197.0
HKD1_k127_5161291_3 carbohydrate transport - - - 0.000000000000000000000000000000000000000000000001242 191.0
HKD1_k127_5161291_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000001097 166.0
HKD1_k127_5161291_5 Transcriptional regulator IclR K13641 - - 0.000000000000000000000001506 105.0
HKD1_k127_5161291_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000004812 83.0
HKD1_k127_5185214_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1246.0
HKD1_k127_5185214_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.0 1234.0
HKD1_k127_5185214_10 Binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002721 279.0
HKD1_k127_5185214_11 Thiamine pyrophosphate enzyme, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001157 256.0
HKD1_k127_5185214_12 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000235 124.0
HKD1_k127_5185214_13 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000000000000005288 108.0
HKD1_k127_5185214_14 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000005706 64.0
HKD1_k127_5185214_15 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0000209 51.0
HKD1_k127_5185214_16 Protein of unknown function (DUF4013) - - - 0.000955 49.0
HKD1_k127_5185214_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.243e-228 720.0
HKD1_k127_5185214_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 603.0
HKD1_k127_5185214_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 509.0
HKD1_k127_5185214_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 391.0
HKD1_k127_5185214_6 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 365.0
HKD1_k127_5185214_7 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 311.0
HKD1_k127_5185214_8 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 291.0
HKD1_k127_5185214_9 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001522 268.0
HKD1_k127_519727_0 Glycogen debranching enzyme - - - 0.0 1355.0
HKD1_k127_519727_1 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 535.0
HKD1_k127_519727_2 Uncharacterized protein conserved in bacteria (DUF2090) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 427.0
HKD1_k127_519727_3 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 340.0
HKD1_k127_519727_4 - - - - 0.00000000000000000000000000000000000002827 148.0
HKD1_k127_5198991_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1353.0
HKD1_k127_5198991_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1255.0
HKD1_k127_5198991_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 397.0
HKD1_k127_5198991_11 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 399.0
HKD1_k127_5198991_12 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 378.0
HKD1_k127_5198991_13 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 364.0
HKD1_k127_5198991_14 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 327.0
HKD1_k127_5198991_15 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000683 286.0
HKD1_k127_5198991_16 Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000137 289.0
HKD1_k127_5198991_17 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002776 287.0
HKD1_k127_5198991_18 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000813 280.0
HKD1_k127_5198991_19 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001148 272.0
HKD1_k127_5198991_2 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0 1148.0
HKD1_k127_5198991_20 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000002681 239.0
HKD1_k127_5198991_21 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.000000000000000000000000000000000000000000000000000000000000000002205 239.0
HKD1_k127_5198991_22 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000184 231.0
HKD1_k127_5198991_23 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000006071 223.0
HKD1_k127_5198991_24 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000004038 236.0
HKD1_k127_5198991_25 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000006749 240.0
HKD1_k127_5198991_26 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000002601 181.0
HKD1_k127_5198991_27 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000000000000000004606 177.0
HKD1_k127_5198991_28 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000000000000008221 157.0
HKD1_k127_5198991_29 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000001373 139.0
HKD1_k127_5198991_3 3-isopropylmalate dehydratase activity K01681,K01703,K17749,K20452 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0030312,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.3,4.2.1.33,4.2.1.35,4.2.1.85 2.242e-219 688.0
HKD1_k127_5198991_30 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000003103 119.0
HKD1_k127_5198991_31 Glyoxalase-like domain K01759 - 4.4.1.5 0.000000000000000000000000374 110.0
HKD1_k127_5198991_32 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000782 117.0
HKD1_k127_5198991_33 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000001291 89.0
HKD1_k127_5198991_34 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000005533 69.0
HKD1_k127_5198991_35 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00007279 50.0
HKD1_k127_5198991_4 Ftsk_gamma K03466 GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 4.876e-219 705.0
HKD1_k127_5198991_5 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - 2.534e-218 690.0
HKD1_k127_5198991_6 B12 binding domain - - - 1.274e-196 633.0
HKD1_k127_5198991_7 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009798 610.0
HKD1_k127_5198991_8 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 499.0
HKD1_k127_5198991_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 438.0
HKD1_k127_5222180_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008315 584.0
HKD1_k127_5222180_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 519.0
HKD1_k127_5222180_2 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 432.0
HKD1_k127_5222180_3 - - - - 0.0000000000000000000000000000000000000000000000000000001895 199.0
HKD1_k127_5222180_4 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.0000000000000000000000001005 113.0
HKD1_k127_5222180_5 - K02275,K17686 - 1.9.3.1,3.6.3.54 0.000000000000000000000006309 115.0
HKD1_k127_5222180_6 Cytochrome c - - - 0.00000000000001074 86.0
HKD1_k127_5222180_7 uridine phosphorylase activity K00757 - 2.4.2.3 0.0000000000000856 73.0
HKD1_k127_5222180_8 Protein of unknown function with PCYCGC motif - - - 0.00000008619 54.0
HKD1_k127_5222180_9 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0001857 44.0
HKD1_k127_5232907_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1289.0
HKD1_k127_5232907_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 400.0
HKD1_k127_5232907_2 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000003632 211.0
HKD1_k127_523324_0 RES - - - 0.0000000000000000000000000000000000000000000000000000000000000000004423 233.0
HKD1_k127_523324_1 Protein of unknown function (DUF2384) - - - 0.000000000000000000000000000000001051 134.0
HKD1_k127_523324_2 N-terminal half of MaoC dehydratase - - - 0.000000000000003439 80.0
HKD1_k127_523324_3 MaoC like domain - - - 0.0000000004698 64.0
HKD1_k127_523324_4 - - - - 0.000000007295 58.0
HKD1_k127_5245889_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 395.0
HKD1_k127_5245889_1 Molybdate transporter of MFS superfamily - - - 0.000000000000000000000000000000000000000000000002899 176.0
HKD1_k127_5245889_2 - - - - 0.0000000000000000000000000000000001078 137.0
HKD1_k127_5252524_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 415.0
HKD1_k127_5252524_1 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000005422 221.0
HKD1_k127_5252524_2 Elements of external origin - - - 0.00000000000000000000000000000007551 128.0
HKD1_k127_5253176_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 415.0
HKD1_k127_5253176_1 ZU5 domain K10380,K21440 GO:0000902,GO:0000904,GO:0001508,GO:0002027,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003205,GO:0003230,GO:0003279,GO:0003283,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005911,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006888,GO:0006928,GO:0006935,GO:0006936,GO:0006937,GO:0006941,GO:0006942,GO:0007009,GO:0007154,GO:0007165,GO:0007267,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007507,GO:0008015,GO:0008016,GO:0008092,GO:0008104,GO:0008150,GO:0009605,GO:0009653,GO:0009893,GO:0009987,GO:0010171,GO:0010256,GO:0010468,GO:0010522,GO:0010604,GO:0010628,GO:0010646,GO:0010880,GO:0010881,GO:0010882,GO:0010959,GO:0014069,GO:0014704,GO:0015459,GO:0016020,GO:0016021,GO:0016043,GO:0016192,GO:0016247,GO:0016323,GO:0016328,GO:0019222,GO:0019722,GO:0019725,GO:0019899,GO:0019900,GO:0019901,GO:0019932,GO:0022008,GO:0022898,GO:0023051,GO:0023052,GO:0030001,GO:0030003,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030030,GO:0030048,GO:0030054,GO:0030154,GO:0030182,GO:0030315,GO:0030507,GO:0030674,GO:0031175,GO:0031224,GO:0031226,GO:0031430,GO:0031647,GO:0031672,GO:0031674,GO:0032279,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032501,GO:0032502,GO:0032879,GO:0032970,GO:0032989,GO:0032990,GO:0033036,GO:0033292,GO:0033365,GO:0033563,GO:0034394,GO:0034613,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0035556,GO:0035637,GO:0036309,GO:0036371,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042330,GO:0042383,GO:0042391,GO:0042592,GO:0042692,GO:0043034,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043266,GO:0043268,GO:0043269,GO:0043270,GO:0043292,GO:0044057,GO:0044093,GO:0044291,GO:0044325,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044449,GO:0044456,GO:0044459,GO:0044464,GO:0045202,GO:0045927,GO:0046907,GO:0048193,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048522,GO:0048638,GO:0048639,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050821,GO:0050839,GO:0050896,GO:0051049,GO:0051050,GO:0051094,GO:0051117,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051270,GO:0051279,GO:0051282,GO:0051641,GO:0051649,GO:0051716,GO:0051899,GO:0051924,GO:0051928,GO:0055001,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055117,GO:0060047,GO:0060048,GO:0060090,GO:0060255,GO:0060306,GO:0060307,GO:0060341,GO:0061024,GO:0061061,GO:0061337,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070252,GO:0070296,GO:0070727,GO:0070838,GO:0070972,GO:0071840,GO:0071944,GO:0072359,GO:0072503,GO:0072507,GO:0072511,GO:0072657,GO:0072659,GO:0086001,GO:0086002,GO:0086003,GO:0086004,GO:0086005,GO:0086010,GO:0086012,GO:0086014,GO:0086015,GO:0086018,GO:0086019,GO:0086026,GO:0086036,GO:0086046,GO:0086065,GO:0086066,GO:0086070,GO:0086091,GO:0090257,GO:0097458,GO:0097485,GO:0098590,GO:0098771,GO:0098772,GO:0098794,GO:0098900,GO:0098901,GO:0098904,GO:0098907,GO:0098910,GO:0098984,GO:0099080,GO:0099081,GO:0099106,GO:0099512,GO:0099572,GO:0099623,GO:0120036,GO:0120039,GO:1901016,GO:1901018,GO:1901019,GO:1901021,GO:1901379,GO:1901381,GO:1903115,GO:1903169,GO:1903522,GO:1903779,GO:1904062,GO:1904064,GO:1904427,GO:1990778,GO:2001257,GO:2001259 - 0.0002115 47.0
HKD1_k127_5253176_2 Nitroreductase family - - - 0.0003338 46.0
HKD1_k127_5275313_0 Cytochrome c K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 344.0
HKD1_k127_5275313_1 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 308.0
HKD1_k127_5275313_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000003084 156.0
HKD1_k127_5275313_3 COG1484 DNA replication protein - - - 0.000000000000000003385 93.0
HKD1_k127_5275313_4 PFAM Integrase - - - 0.00006366 55.0
HKD1_k127_5275313_5 COG1484 DNA replication protein - - - 0.0008996 43.0
HKD1_k127_5286781_0 PFAM Pyridine nucleotide-disulphide oxidoreductase - - - 1.185e-212 673.0
HKD1_k127_5286781_1 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007595 275.0
HKD1_k127_5286781_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.00000005275 54.0
HKD1_k127_5291004_0 COG2414 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 412.0
HKD1_k127_5291004_1 transcriptional regulator - - - 0.0000000000000000000000000003083 118.0
HKD1_k127_5302266_0 Spermine/spermidine synthase domain - - - 1.471e-278 880.0
HKD1_k127_5302266_1 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 6.146e-215 677.0
HKD1_k127_5302266_2 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000004146 223.0
HKD1_k127_5302266_3 Type II secretory pathway, pseudopilin - - - 0.000000000000000001971 89.0
HKD1_k127_5302609_0 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 551.0
HKD1_k127_5302609_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 393.0
HKD1_k127_5302609_2 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000002691 257.0
HKD1_k127_5302609_3 Histidine kinase HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000001573 251.0
HKD1_k127_5302609_4 Protein of unknown function (DUF2283) - - - 0.00000000000001498 77.0
HKD1_k127_5302922_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 559.0
HKD1_k127_5302922_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 436.0
HKD1_k127_5338674_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1307.0
HKD1_k127_5338674_1 NADH ubiquinone oxidoreductase NADH-binding (51 kD) subunit K05587 - 1.6.5.3 8.799e-268 832.0
HKD1_k127_5338674_10 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 439.0
HKD1_k127_5338674_11 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily K00145,K05829 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 422.0
HKD1_k127_5338674_12 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 430.0
HKD1_k127_5338674_13 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 399.0
HKD1_k127_5338674_14 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K05588 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 388.0
HKD1_k127_5338674_15 ArgJ family K00620,K00930 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 390.0
HKD1_k127_5338674_16 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 378.0
HKD1_k127_5338674_17 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 358.0
HKD1_k127_5338674_18 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 357.0
HKD1_k127_5338674_19 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 333.0
HKD1_k127_5338674_2 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K12142,K15830 GO:0003674,GO:0005488,GO:0016151,GO:0043167,GO:0043169,GO:0046872,GO:0046914 1.6.5.3 1.136e-256 817.0
HKD1_k127_5338674_20 Belongs to the complex I 20 kDa subunit family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 305.0
HKD1_k127_5338674_21 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005215 279.0
HKD1_k127_5338674_22 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003991 267.0
HKD1_k127_5338674_23 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12143,K15831 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
HKD1_k127_5338674_24 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000001557 245.0
HKD1_k127_5338674_25 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001154 250.0
HKD1_k127_5338674_26 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000008441 231.0
HKD1_k127_5338674_27 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000001978 223.0
HKD1_k127_5338674_28 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000002968 212.0
HKD1_k127_5338674_29 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000002076 193.0
HKD1_k127_5338674_3 Nickel-dependent hydrogenase K00436 - 1.12.1.2 2.778e-246 767.0
HKD1_k127_5338674_30 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001616 179.0
HKD1_k127_5338674_31 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000001752 179.0
HKD1_k127_5338674_32 spore germination K00442,K08315 - 3.4.23.51 0.000000000000000000000000000000000002442 154.0
HKD1_k127_5338674_33 TIGRFAM hydrogenase maturation protease - - - 0.00000000000000000000000000002833 126.0
HKD1_k127_5338674_34 - - - - 0.0000000000000000000000001871 109.0
HKD1_k127_5338674_35 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000007846 94.0
HKD1_k127_5338674_36 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000007957 85.0
HKD1_k127_5338674_37 - - - - 0.00000000002616 72.0
HKD1_k127_5338674_38 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000005507 66.0
HKD1_k127_5338674_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 1.222e-244 774.0
HKD1_k127_5338674_5 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 1.259e-220 708.0
HKD1_k127_5338674_6 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 1.603e-200 637.0
HKD1_k127_5338674_7 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 580.0
HKD1_k127_5338674_8 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 551.0
HKD1_k127_5338674_9 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 491.0
HKD1_k127_5355053_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 479.0
HKD1_k127_5355053_1 SAM-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 407.0
HKD1_k127_5355053_2 ABC transporter K06147,K18890 - - 0.00000000000000000000000000002446 118.0
HKD1_k127_5379905_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000236 211.0
HKD1_k127_5379905_1 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.00000000000000000000000003642 111.0
HKD1_k127_5381168_0 coagulation factor 5 8 type - - - 0.0 1140.0
HKD1_k127_5381168_1 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 4.219e-219 687.0
HKD1_k127_5381168_2 Protein conserved in bacteria - - - 3.176e-198 630.0
HKD1_k127_5381168_3 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 556.0
HKD1_k127_5381168_4 ABC-type sugar transport systems, permease components K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 444.0
HKD1_k127_5381168_5 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002168 287.0
HKD1_k127_5381168_6 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002073 261.0
HKD1_k127_5381168_7 alcohol dehydrogenase K13954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000002624 232.0
HKD1_k127_5381168_8 Binding-protein-dependent transport system inner membrane component K02026,K10119 - - 0.000000000000000000000000000000000000000000000000000000000136 213.0
HKD1_k127_5381168_9 Fibrillar collagens C-terminal domain K19721 GO:0002244,GO:0002376,GO:0002520,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0007275,GO:0008150,GO:0009987,GO:0012505,GO:0030097,GO:0030154,GO:0031974,GO:0032501,GO:0032502,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048513,GO:0048534,GO:0048731,GO:0048856,GO:0048869,GO:0070013 - 0.00000004669 66.0
HKD1_k127_5385534_0 AcrB/AcrD/AcrF family K21134 - - 0.0 1412.0
HKD1_k127_5385534_1 recombinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 580.0
HKD1_k127_5385534_2 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 397.0
HKD1_k127_5385534_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001377 237.0
HKD1_k127_5385534_4 Recombinase - - - 0.000000000000000000000000000000000000000000000006814 183.0
HKD1_k127_5385534_5 - - - - 0.0000000000000000008978 89.0
HKD1_k127_5385534_6 Alpha/beta hydrolase family - - - 0.0000002632 52.0
HKD1_k127_5385534_7 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0001254 46.0
HKD1_k127_5394465_0 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 4.157e-197 623.0
HKD1_k127_5394465_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 480.0
HKD1_k127_5394465_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 468.0
HKD1_k127_5394465_3 Belongs to the D-alanine--D-alanine ligase family K01921,K01924 - 6.3.2.4,6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 451.0
HKD1_k127_5394465_4 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 373.0
HKD1_k127_5394465_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 342.0
HKD1_k127_5394465_6 Cell wall formation K00075,K01921 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0022603,GO:0022604,GO:0030203,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0055114,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.98,6.3.2.4 0.000000000000000000000000000000000000000002395 163.0
HKD1_k127_5394645_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 546.0
HKD1_k127_5394645_1 mannitol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 526.0
HKD1_k127_5394645_10 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 351.0
HKD1_k127_5394645_11 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 341.0
HKD1_k127_5394645_12 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K21395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 321.0
HKD1_k127_5394645_13 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 319.0
HKD1_k127_5394645_14 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 309.0
HKD1_k127_5394645_15 Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001151 267.0
HKD1_k127_5394645_16 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000002732 222.0
HKD1_k127_5394645_17 TRAP transporter, solute receptor (TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000007285 204.0
HKD1_k127_5394645_18 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000001016 195.0
HKD1_k127_5394645_19 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000000000000000000000000000000006521 179.0
HKD1_k127_5394645_2 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 496.0
HKD1_k127_5394645_20 Transcriptional regulator IclR - - - 0.0000000000000000000000000000000000000000000001569 177.0
HKD1_k127_5394645_21 Transcriptional regulator IclR K13641 - - 0.000000000000000000000000000000000000000000001003 178.0
HKD1_k127_5394645_22 Transcriptional regulator IclR K13641 - - 0.000000000000000000000000000000000000000001487 166.0
HKD1_k127_5394645_23 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000005453 154.0
HKD1_k127_5394645_24 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000005575 110.0
HKD1_k127_5394645_25 PFAM NIPSNAP family containing protein - - - 0.00000000000001011 88.0
HKD1_k127_5394645_26 Tripartite tricarboxylate transporter TctB family - - - 0.000000000004473 75.0
HKD1_k127_5394645_27 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000001055 65.0
HKD1_k127_5394645_28 membrane K07794 - - 0.000003768 55.0
HKD1_k127_5394645_3 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 474.0
HKD1_k127_5394645_4 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 481.0
HKD1_k127_5394645_5 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 464.0
HKD1_k127_5394645_6 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 460.0
HKD1_k127_5394645_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 391.0
HKD1_k127_5394645_8 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 364.0
HKD1_k127_5394645_9 MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 373.0
HKD1_k127_5404058_0 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000000000000000000000003121 223.0
HKD1_k127_5404058_2 - - - - 0.00001422 53.0
HKD1_k127_5410414_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 411.0
HKD1_k127_5410414_1 Protein conserved in bacteria K07465 - - 0.0000000000000000000006935 105.0
HKD1_k127_5410414_2 Recombinase zinc beta ribbon domain K06400 - - 0.00001443 53.0
HKD1_k127_5411476_0 COG COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007716 290.0
HKD1_k127_5411476_1 creatinase - - - 0.0000000000000000000000000000000000000128 152.0
HKD1_k127_5439605_0 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 600.0
HKD1_k127_5439605_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 366.0
HKD1_k127_5439605_2 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 338.0
HKD1_k127_5439605_3 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000001165 86.0
HKD1_k127_5439605_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000001309 65.0
HKD1_k127_5439605_5 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0001071 44.0
HKD1_k127_5440644_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 4399.0
HKD1_k127_5440644_1 protein with a C-terminal OMP (outer membrane protein) domain - - - 0.0000000000000000000000008771 115.0
HKD1_k127_5440671_0 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 310.0
HKD1_k127_5440671_1 PFAM ABC transporter related K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000006441 259.0
HKD1_k127_5440671_2 spermidine putrescine K02054 - - 0.0000000000000000000000000000000000000000002071 162.0
HKD1_k127_5446438_0 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 400.0
HKD1_k127_5446438_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 352.0
HKD1_k127_5446438_2 Belongs to the ABC transporter superfamily K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001098 300.0
HKD1_k127_5446438_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000357 243.0
HKD1_k127_5446438_4 molybdate ABC transporter, permease protein K02017,K02018 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000003653 229.0
HKD1_k127_5446438_5 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000008861 222.0
HKD1_k127_5446438_6 glycolate biosynthetic process K01091,K06019 - 3.1.3.18,3.6.1.1 0.00000000000000000000000000000000000000000000000000000000143 209.0
HKD1_k127_5446438_7 RNA recognition motif - - - 0.0000000000000000000000000000000000000000009979 162.0
HKD1_k127_5446438_8 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000008746 130.0
HKD1_k127_5446438_9 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.0000000002202 69.0
HKD1_k127_5458377_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 551.0
HKD1_k127_5458377_1 transcriptional regulator, AsnC family - - - 0.00000000000001659 74.0
HKD1_k127_5509616_0 Tripartite tricarboxylate transporter TctA family K07793 - - 2.072e-216 682.0
HKD1_k127_5509616_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 515.0
HKD1_k127_5509616_10 Catalyzes a trans-dehydration via an enolate intermediate K01271,K03785,K03786,K16021 GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 3.4.13.9,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000003638 225.0
HKD1_k127_5509616_11 Pfam:Methyltransf_6 K10218 - 4.1.3.17 0.0000000000000000000000000000000000000000000000000000001957 205.0
HKD1_k127_5509616_12 alcohol dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000000000000000000000000000000000000000000000000000158 205.0
HKD1_k127_5509616_13 NIPSNAP - - - 0.0000000000000000000000000000000000005081 143.0
HKD1_k127_5509616_14 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000006864 144.0
HKD1_k127_5509616_15 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000000000009426 112.0
HKD1_k127_5509616_16 regulatory protein GntR HTH - - - 0.000000000000000000000000844 113.0
HKD1_k127_5509616_17 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.00000000000000000000001816 107.0
HKD1_k127_5509616_18 TIGRFAM MoaD family protein K03636 - - 0.00000000000001597 79.0
HKD1_k127_5509616_19 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000002895 78.0
HKD1_k127_5509616_2 mannitol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 441.0
HKD1_k127_5509616_20 Domain of unknown function (DUF309) K09763 - - 0.00000000000003227 80.0
HKD1_k127_5509616_21 Protein of unknown function (DUF861) - - - 0.0000000002549 66.0
HKD1_k127_5509616_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 428.0
HKD1_k127_5509616_4 Creatinine amidohydrolase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 409.0
HKD1_k127_5509616_5 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 347.0
HKD1_k127_5509616_6 carbohydrate transport K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 347.0
HKD1_k127_5509616_7 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 301.0
HKD1_k127_5509616_8 proline dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 299.0
HKD1_k127_5509616_9 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006351 277.0
HKD1_k127_5519588_0 Belongs to the glycosyl hydrolase 13 family - - - 1.45e-321 1005.0
HKD1_k127_5519588_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 2.858e-217 682.0
HKD1_k127_5519588_2 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 432.0
HKD1_k127_5519588_3 - - - - 0.0000000000000000001267 95.0
HKD1_k127_5522122_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.02e-236 740.0
HKD1_k127_5522122_1 Sulfate permease family - - - 1.413e-232 733.0
HKD1_k127_5522122_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000008152 239.0
HKD1_k127_5522122_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000001875 222.0
HKD1_k127_5522122_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000001391 111.0
HKD1_k127_5547180_0 helicase superfamily c-terminal domain K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 1.082e-294 925.0
HKD1_k127_5547180_1 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 595.0
HKD1_k127_5547180_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 342.0
HKD1_k127_5547180_11 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000003295 107.0
HKD1_k127_5547180_12 response regulator receiver K02481,K07714 - - 0.000000000000000000002749 99.0
HKD1_k127_5547180_13 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000004999 92.0
HKD1_k127_5547180_14 PFAM nuclease (SNase domain protein) - - - 0.000000000000002903 83.0
HKD1_k127_5547180_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 561.0
HKD1_k127_5547180_3 PFAM aminotransferase class-III K01845,K21585 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006083,GO:0006091,GO:0006113,GO:0006520,GO:0006553,GO:0006554,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0015980,GO:0016020,GO:0016054,GO:0016740,GO:0016769,GO:0016853,GO:0016866,GO:0016869,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019475,GO:0019477,GO:0019665,GO:0019666,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044464,GO:0046148,GO:0046395,GO:0046440,GO:0046483,GO:0046501,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 2.6.1.111,5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 555.0
HKD1_k127_5547180_4 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 513.0
HKD1_k127_5547180_5 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 531.0
HKD1_k127_5547180_6 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 498.0
HKD1_k127_5547180_7 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 455.0
HKD1_k127_5547180_8 Alanine dehydrogenase/PNT, C-terminal domain K00324 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 383.0
HKD1_k127_5547180_9 SMART Elongator protein 3 MiaB NifB K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 349.0
HKD1_k127_5549262_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001673 291.0
HKD1_k127_5549262_1 COG3385 FOG Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000007241 212.0
HKD1_k127_5549262_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000018 76.0
HKD1_k127_5563241_0 PFAM peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 362.0
HKD1_k127_5563241_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 355.0
HKD1_k127_5563241_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 337.0
HKD1_k127_5563241_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 334.0
HKD1_k127_5563241_4 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 336.0
HKD1_k127_5563241_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000001885 228.0
HKD1_k127_5563241_6 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000000000000000005172 124.0
HKD1_k127_5564343_0 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 413.0
HKD1_k127_5564343_1 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003157 263.0
HKD1_k127_5564343_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000003214 231.0
HKD1_k127_5564343_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000003609 237.0
HKD1_k127_5566108_0 Alpha-L-fucosidase K01206 - 3.2.1.51 2.73e-263 818.0
HKD1_k127_55665_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 564.0
HKD1_k127_55665_1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases K18369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 546.0
HKD1_k127_55665_2 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 438.0
HKD1_k127_55665_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 418.0
HKD1_k127_55665_4 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000000000000000000000000000000000000003356 198.0
HKD1_k127_55665_5 Essential cell division protein K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000000000000003426 173.0
HKD1_k127_55665_6 Cell wall formation K00075,K01921 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0022603,GO:0022604,GO:0030203,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0055114,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.98,6.3.2.4 0.0000000000000000000000000000008289 123.0
HKD1_k127_5567682_0 COG3385 FOG Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 501.0
HKD1_k127_5575894_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1273.0
HKD1_k127_5575894_1 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 359.0
HKD1_k127_5575894_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 337.0
HKD1_k127_5575894_3 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 303.0
HKD1_k127_5575894_4 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000108 241.0
HKD1_k127_5575894_5 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000005545 234.0
HKD1_k127_5575894_6 2-keto-3-deoxy-L-rhamnonate aldolase activity K01630,K02510 - 4.1.2.20,4.1.2.52 0.00000000000000000000000000000000000000000000000000000000002858 218.0
HKD1_k127_5575894_7 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000000001652 167.0
HKD1_k127_5575894_8 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000218 88.0
HKD1_k127_56091_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 319.0
HKD1_k127_56091_1 inositol 2-dehydrogenase activity K00010,K03810 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004425 287.0
HKD1_k127_56091_10 Dak1 domain K00863,K05878 - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 0.000005826 57.0
HKD1_k127_56091_2 COG1175 ABC-type sugar transport systems permease components K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005195 252.0
HKD1_k127_56091_3 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003885 238.0
HKD1_k127_56091_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005088 227.0
HKD1_k127_56091_5 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000005561 206.0
HKD1_k127_56091_6 Binding-protein-dependent transport system inner membrane component K02026,K10229 - - 0.00000000000000000000000000000000000000000000000000237 201.0
HKD1_k127_56091_7 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000002267 152.0
HKD1_k127_56091_8 FCD - - - 0.00000000000000000000000006742 115.0
HKD1_k127_56091_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000002133 94.0
HKD1_k127_5609397_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 523.0
HKD1_k127_5609397_1 ABC-type sugar transport system periplasmic component K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 475.0
HKD1_k127_5609397_10 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 302.0
HKD1_k127_5609397_11 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 297.0
HKD1_k127_5609397_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 295.0
HKD1_k127_5609397_13 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002566 284.0
HKD1_k127_5609397_14 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000004431 233.0
HKD1_k127_5609397_15 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000001745 229.0
HKD1_k127_5609397_16 COG1175 ABC-type sugar transport systems, permease components K02025 - - 0.000000000000000000000000000000000000000000000000000001762 202.0
HKD1_k127_5609397_17 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000779 206.0
HKD1_k127_5609397_18 dehydratase - - - 0.00000000000000000000000000000000000000000000000001126 193.0
HKD1_k127_5609397_19 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000001149 180.0
HKD1_k127_5609397_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 449.0
HKD1_k127_5609397_20 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases K00008 - 1.1.1.14 0.0000000000000000000000000000000000002847 145.0
HKD1_k127_5609397_21 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000001074 155.0
HKD1_k127_5609397_22 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000345 149.0
HKD1_k127_5609397_23 FCD domain - - - 0.000000000000000000000000102 116.0
HKD1_k127_5609397_24 Transcriptional regulator GntR family - - - 0.0000000000000000000004834 105.0
HKD1_k127_5609397_3 Phosphotriesterase K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 440.0
HKD1_k127_5609397_4 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 438.0
HKD1_k127_5609397_5 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 424.0
HKD1_k127_5609397_6 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 356.0
HKD1_k127_5609397_7 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 346.0
HKD1_k127_5609397_8 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 312.0
HKD1_k127_5609397_9 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 331.0
HKD1_k127_5626899_0 PFAM Integrase, catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 599.0
HKD1_k127_5626899_1 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002538 272.0
HKD1_k127_5642836_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528,K16203 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 333.0
HKD1_k127_5642836_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000003455 241.0
HKD1_k127_5642836_2 Aldo/keto reductase family - - - 0.00007463 45.0
HKD1_k127_5649199_0 AsmA family K07289,K07290 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 423.0
HKD1_k127_5649199_1 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000008018 228.0
HKD1_k127_5649199_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002513 216.0
HKD1_k127_5649199_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000001493 141.0
HKD1_k127_5649199_4 - - - - 0.0000000000000000000000002797 109.0
HKD1_k127_5654407_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 373.0
HKD1_k127_5654407_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 334.0
HKD1_k127_5654407_2 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 301.0
HKD1_k127_5654407_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001499 291.0
HKD1_k127_5654407_4 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000406 274.0
HKD1_k127_5654407_5 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000527 230.0
HKD1_k127_5654407_6 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000000001775 183.0
HKD1_k127_5654407_7 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000001061 186.0
HKD1_k127_5654407_8 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00176 - 1.2.7.3 0.000007971 50.0
HKD1_k127_5654407_9 Bacterial extracellular solute-binding protein K02027 - - 0.0006171 45.0
HKD1_k127_5687528_0 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 324.0
HKD1_k127_5687528_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 302.0
HKD1_k127_5687528_2 Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.00000000000000000008562 90.0
HKD1_k127_5707045_0 Trap dicarboxylate transporter, dctm subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 305.0
HKD1_k127_5707045_1 PFAM Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000001531 214.0
HKD1_k127_5707045_2 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000401 203.0
HKD1_k127_5707045_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000001185 194.0
HKD1_k127_5707045_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000006426 97.0
HKD1_k127_5707045_5 DNA topological change - - - 0.00000000000000000001328 93.0
HKD1_k127_5707045_6 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000005238 58.0
HKD1_k127_5726241_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 1.137e-199 629.0
HKD1_k127_5726241_1 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 570.0
HKD1_k127_5726241_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 377.0
HKD1_k127_5726241_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 357.0
HKD1_k127_5726241_4 Iron-containing alcohol dehydrogenase K19954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 325.0
HKD1_k127_5726241_5 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 301.0
HKD1_k127_5726241_6 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000001067 217.0
HKD1_k127_5726241_7 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain K02030 - - 0.000000000000000000000000000000000000000000000003591 186.0
HKD1_k127_5726241_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000408 63.0
HKD1_k127_5726241_9 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000001766 57.0
HKD1_k127_572885_0 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 389.0
HKD1_k127_572885_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 347.0
HKD1_k127_572885_2 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 331.0
HKD1_k127_572885_3 amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000001694 240.0
HKD1_k127_572885_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000002931 117.0
HKD1_k127_5740601_0 COG4166 ABC-type oligopeptide transport system, periplasmic component K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 493.0
HKD1_k127_5740601_1 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 488.0
HKD1_k127_5740601_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 497.0
HKD1_k127_5740601_3 'ABC-type dipeptide oligopeptide nickel transport K02033,K15581,K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 393.0
HKD1_k127_5740601_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 351.0
HKD1_k127_5740601_5 Binding-protein-dependent transport system inner membrane component K15582 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 320.0
HKD1_k127_5740601_6 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 310.0
HKD1_k127_5740601_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000004803 196.0
HKD1_k127_5740601_8 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000007407 151.0
HKD1_k127_5740601_9 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000003385 94.0
HKD1_k127_5759769_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 292.0
HKD1_k127_5759769_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000006282 163.0
HKD1_k127_5806761_0 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 407.0
HKD1_k127_5806761_1 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001298 271.0
HKD1_k127_5806761_2 Belongs to the SfsA family K06206 - - 0.0000000001013 64.0
HKD1_k127_582445_0 electron transfer activity K02660 - - 0.000000000000000000000000000000000000000005065 162.0
HKD1_k127_582445_1 Glycosyl hydrolases family 38 C-terminal domain - - - 0.000000000009607 78.0
HKD1_k127_5842797_0 FAD linked oxidase domain protein - - - 0.0 1031.0
HKD1_k127_5842797_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 323.0
HKD1_k127_5842797_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001972 263.0
HKD1_k127_5842797_3 - - - - 0.00000000000000000000000227 104.0
HKD1_k127_5849655_0 transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 313.0
HKD1_k127_5849655_1 DinB superfamily - - - 0.000000000000000000000000005858 113.0
HKD1_k127_5863285_2 - - - - 0.00000002527 58.0
HKD1_k127_5863366_0 Glycosyl transferase family 21 K03669 - - 4.958e-304 955.0
HKD1_k127_5863366_1 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009628,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0050896,GO:0051273,GO:0051274,GO:0071704,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 523.0
HKD1_k127_5863366_2 GYD domain - - - 0.0000000000000000000000000000000006751 135.0
HKD1_k127_5863366_3 Lipocalin-like domain - - - 0.000000000000000000000000000000001936 141.0
HKD1_k127_5874954_0 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 415.0
HKD1_k127_5874954_1 best DB hits BLAST gb AAD45539.1 - - - 0.00000000000000000000005491 105.0
HKD1_k127_5874954_2 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.000000000000003527 89.0
HKD1_k127_5882337_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000003364 220.0
HKD1_k127_5882337_1 Pyridine nucleotide-disulphide oxidoreductase K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000047 206.0
HKD1_k127_5882337_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000006188 166.0
HKD1_k127_5918303_0 ErfK YbiS YcfS YnhG family protein K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 316.0
HKD1_k127_5918303_1 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.000000000000000000006385 96.0
HKD1_k127_5943789_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 378.0
HKD1_k127_5943789_1 Zinc-binding dehydrogenase K00008,K00060 - 1.1.1.103,1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 369.0
HKD1_k127_5943789_2 Transketolase, thiamine diphosphate binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 364.0
HKD1_k127_5943789_3 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007633 361.0
HKD1_k127_5943789_4 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000005892 258.0
HKD1_k127_5943789_5 Asp/Glu/Hydantoin racemase - - - 0.00000000000000000000000000000000000000000000000000000000000001004 222.0
HKD1_k127_5943789_6 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000007166 178.0
HKD1_k127_5943789_7 Putative nucleotide-binding of sugar-metabolising enzyme K22129 - 2.7.1.219,2.7.1.220 0.0000002247 53.0
HKD1_k127_5970513_0 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 462.0
HKD1_k127_5970513_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000373 284.0
HKD1_k127_5970513_2 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000003217 247.0
HKD1_k127_5970767_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 348.0
HKD1_k127_5970767_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 294.0
HKD1_k127_5970767_2 metal-dependent enzyme of the double-stranded beta helix superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001981 217.0
HKD1_k127_5970767_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000001902 188.0
HKD1_k127_5970767_4 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000001057 125.0
HKD1_k127_5970767_5 GYD domain - - - 0.0007204 44.0
HKD1_k127_598195_0 COG1982 Arginine lysine ornithine decarboxylases K01584 - 4.1.1.19 5.349e-289 898.0
HKD1_k127_598195_1 potassium ion transport K07085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 336.0
HKD1_k127_5982441_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 1.381e-196 628.0
HKD1_k127_5982441_1 Major facilitator Superfamily K03446,K07786 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 444.0
HKD1_k127_5982441_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) - - - 0.00000003294 55.0
HKD1_k127_5982441_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00001142 51.0
HKD1_k127_6009127_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 1.802e-274 872.0
HKD1_k127_6009127_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 5.406e-210 666.0
HKD1_k127_6009127_11 - - - - 0.0000000000000000000001423 112.0
HKD1_k127_6009127_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 479.0
HKD1_k127_6009127_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 361.0
HKD1_k127_6009127_4 PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005497 237.0
HKD1_k127_6009127_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000003759 220.0
HKD1_k127_6009127_6 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000003573 214.0
HKD1_k127_6009127_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.000000000000000000000000000000000000000000000000000000002623 205.0
HKD1_k127_6009127_8 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272,K21345 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000006209 181.0
HKD1_k127_6009127_9 Probable zinc-ribbon domain K03704 - - 0.000000000000000000000000000000000003192 139.0
HKD1_k127_6015768_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1178.0
HKD1_k127_6015768_1 Succinyl-CoA ligase like flavodoxin domain K18594 - - 0.0 1079.0
HKD1_k127_6015768_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 567.0
HKD1_k127_6015768_11 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 556.0
HKD1_k127_6015768_12 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 552.0
HKD1_k127_6015768_13 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 515.0
HKD1_k127_6015768_14 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 518.0
HKD1_k127_6015768_15 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 499.0
HKD1_k127_6015768_16 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 502.0
HKD1_k127_6015768_17 oxidative phosphorylation K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 494.0
HKD1_k127_6015768_18 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 485.0
HKD1_k127_6015768_19 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 463.0
HKD1_k127_6015768_2 Protein involved in outer membrane biogenesis - - - 8.67e-267 872.0
HKD1_k127_6015768_20 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 462.0
HKD1_k127_6015768_21 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 457.0
HKD1_k127_6015768_22 Methanol-cobalamin methyltransferase B subunit K04480 - 2.1.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 456.0
HKD1_k127_6015768_23 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0040007,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 411.0
HKD1_k127_6015768_24 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 409.0
HKD1_k127_6015768_25 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 353.0
HKD1_k127_6015768_26 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 359.0
HKD1_k127_6015768_27 L-phenylalanine transmembrane transporter activity K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 347.0
HKD1_k127_6015768_28 Glutamate formiminotransferase K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 332.0
HKD1_k127_6015768_29 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 318.0
HKD1_k127_6015768_3 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.412e-264 828.0
HKD1_k127_6015768_30 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001508 288.0
HKD1_k127_6015768_31 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002956 285.0
HKD1_k127_6015768_32 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007258 263.0
HKD1_k127_6015768_33 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000007629 222.0
HKD1_k127_6015768_34 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000006668 215.0
HKD1_k127_6015768_35 domain protein K06929 - - 0.000000000000000000000000000000000000000000000000000005502 204.0
HKD1_k127_6015768_36 Permeases of the drug metabolite transporter (DMT) K03298 - - 0.00000000000000000000000000000000000000000163 167.0
HKD1_k127_6015768_37 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000002489 162.0
HKD1_k127_6015768_38 GtrA-like protein - - - 0.00000000000000000000000000000000000000001232 178.0
HKD1_k127_6015768_39 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000149 156.0
HKD1_k127_6015768_4 PFAM Cys Met metabolism pyridoxal-phosphate- dependent protein K01740,K10764 - 2.5.1.49 2.007e-226 706.0
HKD1_k127_6015768_40 - - - - 0.0000000000000000000000000000000000008297 148.0
HKD1_k127_6015768_41 Membrane - - - 0.0000000000000000008224 93.0
HKD1_k127_6015768_43 - - - - 0.000000003551 61.0
HKD1_k127_6015768_44 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.000000983 56.0
HKD1_k127_6015768_45 Homocysteine S-methyltransferase - - - 0.000001428 55.0
HKD1_k127_6015768_47 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0001884 47.0
HKD1_k127_6015768_5 PFAM glycosyl transferase family 39 - - - 2.327e-219 720.0
HKD1_k127_6015768_6 PFAM Asparagine synthase K01953 - 6.3.5.4 1.357e-213 689.0
HKD1_k127_6015768_7 PFAM Cys Met metabolism K01740 - 2.5.1.49 1.795e-209 657.0
HKD1_k127_6015768_8 PFAM Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 580.0
HKD1_k127_6015768_9 aerobic electron transport chain K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 580.0
HKD1_k127_6027976_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 534.0
HKD1_k127_6027976_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 511.0
HKD1_k127_6027976_2 SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 260.0
HKD1_k127_6027976_3 - - - - 0.0000000000315 68.0
HKD1_k127_603682_0 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000007054 167.0
HKD1_k127_603682_1 - - - - 0.000002163 59.0
HKD1_k127_6042143_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 554.0
HKD1_k127_6042143_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 537.0
HKD1_k127_6042143_10 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 392.0
HKD1_k127_6042143_11 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 381.0
HKD1_k127_6042143_12 Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 378.0
HKD1_k127_6042143_13 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 359.0
HKD1_k127_6042143_14 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 335.0
HKD1_k127_6042143_15 NAD binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 291.0
HKD1_k127_6042143_16 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000001306 263.0
HKD1_k127_6042143_17 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000003559 266.0
HKD1_k127_6042143_18 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004715 251.0
HKD1_k127_6042143_19 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000008577 224.0
HKD1_k127_6042143_2 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 517.0
HKD1_k127_6042143_20 Pfam:Methyltransf_6 K10218 - 4.1.3.17 0.0000000000000000000000000000000000001617 150.0
HKD1_k127_6042143_21 Putative cyclase - - - 0.0000000000000000000000000000000001514 142.0
HKD1_k127_6042143_22 gas vesicle protein - - - 0.00000000000000000000000000003846 121.0
HKD1_k127_6042143_24 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000002683 114.0
HKD1_k127_6042143_25 PFAM transport-associated - - - 0.000000000000000000000005767 113.0
HKD1_k127_6042143_26 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000003534 91.0
HKD1_k127_6042143_27 DsrE/DsrF-like family - - - 0.00000000000000006219 91.0
HKD1_k127_6042143_28 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000003396 74.0
HKD1_k127_6042143_29 Transposase - - - 0.000006696 52.0
HKD1_k127_6042143_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 462.0
HKD1_k127_6042143_4 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 442.0
HKD1_k127_6042143_5 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 424.0
HKD1_k127_6042143_6 COG0001 Glutamate-1-semialdehyde aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 424.0
HKD1_k127_6042143_7 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 427.0
HKD1_k127_6042143_8 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 414.0
HKD1_k127_6042143_9 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 388.0
HKD1_k127_6054863_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 7.791e-252 788.0
HKD1_k127_6054863_1 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 482.0
HKD1_k127_6054863_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 396.0
HKD1_k127_6054863_3 DNA recombination-mediator protein A K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 315.0
HKD1_k127_6054863_4 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001096 275.0
HKD1_k127_6054863_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000002904 204.0
HKD1_k127_6054863_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000007667 204.0
HKD1_k127_6054863_7 Lysin motif - - - 0.000000000000000000000000000008252 136.0
HKD1_k127_6054866_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01582,K01585 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.18,4.1.1.19 1.627e-199 634.0
HKD1_k127_6054866_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 479.0
HKD1_k127_6064434_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 604.0
HKD1_k127_6064434_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 469.0
HKD1_k127_6064434_2 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000001373 195.0
HKD1_k127_6064434_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000002303 185.0
HKD1_k127_6064434_4 Protein of unknown function (DUF4019) - - - 0.00000000000000000000000000000000005898 139.0
HKD1_k127_6064434_5 PFAM CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000002674 138.0
HKD1_k127_6064434_6 - - - - 0.000000000000000000000001192 107.0
HKD1_k127_6064434_7 - - - - 0.000000000000000009116 85.0
HKD1_k127_6064434_8 Isochorismatase family - - - 0.0000000000000001915 87.0
HKD1_k127_6064434_9 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K20444 - 2.1.1.222,2.1.1.64 0.000000001245 67.0
HKD1_k127_6089864_0 transposase activity - - - 0.0000000000000000113 91.0
HKD1_k127_6089864_1 transposase activity - - - 0.0000000000000000237 89.0
HKD1_k127_6104047_0 PFAM peptidase K21471 - - 0.000000000000000000000000000000000000000007905 172.0
HKD1_k127_6104047_1 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000009292 126.0
HKD1_k127_6104047_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000005121 64.0
HKD1_k127_6106318_0 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 533.0
HKD1_k127_6106318_1 PFAM Mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 396.0
HKD1_k127_6106318_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 394.0
HKD1_k127_6106318_3 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 368.0
HKD1_k127_6106318_4 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 345.0
HKD1_k127_6106318_5 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002084 277.0
HKD1_k127_6106318_6 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000001599 199.0
HKD1_k127_6106318_7 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000109 195.0
HKD1_k127_6106318_8 PFAM Glycoside hydrolase, family 13 - - - 0.00000000000000000000000000000000112 137.0
HKD1_k127_6106318_9 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000007859 57.0
HKD1_k127_6115185_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 351.0
HKD1_k127_6124377_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1323.0
HKD1_k127_6124377_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 358.0
HKD1_k127_6127113_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 3.867e-312 968.0
HKD1_k127_6127113_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.393e-275 857.0
HKD1_k127_6127113_10 ATP synthesis coupled electron transport K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 327.0
HKD1_k127_6127113_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 317.0
HKD1_k127_6127113_12 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003571 265.0
HKD1_k127_6127113_13 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000002623 205.0
HKD1_k127_6127113_14 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000001979 197.0
HKD1_k127_6127113_15 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000006537 196.0
HKD1_k127_6127113_16 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000024 167.0
HKD1_k127_6127113_17 Serine aminopeptidase, S33 K09023 - - 0.000000000000000000000000000000005963 139.0
HKD1_k127_6127113_18 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000002261 132.0
HKD1_k127_6127113_19 - - - - 0.00000000000000000000000002718 112.0
HKD1_k127_6127113_2 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05559,K05565 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 619.0
HKD1_k127_6127113_20 4Fe-4S binding domain - - - 0.00000000000000000000005491 105.0
HKD1_k127_6127113_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000268 90.0
HKD1_k127_6127113_22 Mo-molybdopterin cofactor metabolic process K03636 - - 0.0000000000000001257 82.0
HKD1_k127_6127113_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 490.0
HKD1_k127_6127113_4 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 471.0
HKD1_k127_6127113_5 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 426.0
HKD1_k127_6127113_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 419.0
HKD1_k127_6127113_7 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K01782 GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 429.0
HKD1_k127_6127113_8 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 423.0
HKD1_k127_6127113_9 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 374.0
HKD1_k127_6132842_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 455.0
HKD1_k127_6132842_1 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 373.0
HKD1_k127_6132842_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 356.0
HKD1_k127_6132842_3 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 332.0
HKD1_k127_6132842_4 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 326.0
HKD1_k127_6132842_5 Dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.00000000000000000000000000000000000000000000000000000000000000000000000000209 263.0
HKD1_k127_6132842_6 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000003827 179.0
HKD1_k127_6141720_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 589.0
HKD1_k127_6141720_1 Tetratricopeptide repeat K11935 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 544.0
HKD1_k127_6141720_10 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 417.0
HKD1_k127_6141720_11 Large family of predicted nucleotide-binding domains - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 389.0
HKD1_k127_6141720_12 ABC transporter permease K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 346.0
HKD1_k127_6141720_13 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 342.0
HKD1_k127_6141720_14 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 339.0
HKD1_k127_6141720_15 ABC transporter permease K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 328.0
HKD1_k127_6141720_16 ABC-type dipeptide oligopeptide nickel transport K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 326.0
HKD1_k127_6141720_17 PFAM Xylose isomerase domain-containing protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 315.0
HKD1_k127_6141720_18 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004433 280.0
HKD1_k127_6141720_19 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007425 278.0
HKD1_k127_6141720_2 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 522.0
HKD1_k127_6141720_20 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007753 268.0
HKD1_k127_6141720_21 PFAM NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001099 253.0
HKD1_k127_6141720_22 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004762 254.0
HKD1_k127_6141720_23 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000001837 238.0
HKD1_k127_6141720_24 CarD-like/TRCF domain K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.0000000000000000000000000000000000000000000000000000000000007951 215.0
HKD1_k127_6141720_25 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000003075 214.0
HKD1_k127_6141720_26 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001127 209.0
HKD1_k127_6141720_27 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000093 205.0
HKD1_k127_6141720_28 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000007808 205.0
HKD1_k127_6141720_29 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000001785 200.0
HKD1_k127_6141720_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 490.0
HKD1_k127_6141720_30 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000003059 190.0
HKD1_k127_6141720_31 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000307 185.0
HKD1_k127_6141720_32 Predicted membrane protein (DUF2232) K16785,K16786,K16787 - - 0.000000000000000000000000000000000001338 157.0
HKD1_k127_6141720_33 Peptidase MA superfamily - - - 0.0000000000000000000000000000000002471 149.0
HKD1_k127_6141720_34 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000272 135.0
HKD1_k127_6141720_35 Thioesterase superfamily - - - 0.00000000000000000000000000000003469 131.0
HKD1_k127_6141720_36 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000003961 118.0
HKD1_k127_6141720_37 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000000000000000000965 109.0
HKD1_k127_6141720_38 Binds together with S18 to 16S ribosomal RNA K01754,K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 4.3.1.19 0.0000000000000000000000004827 108.0
HKD1_k127_6141720_39 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000004234 85.0
HKD1_k127_6141720_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 458.0
HKD1_k127_6141720_40 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000009105 70.0
HKD1_k127_6141720_41 - - - - 0.000009358 57.0
HKD1_k127_6141720_5 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 453.0
HKD1_k127_6141720_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 454.0
HKD1_k127_6141720_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 444.0
HKD1_k127_6141720_8 Family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 430.0
HKD1_k127_6141720_9 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 415.0
HKD1_k127_6148453_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 357.0
HKD1_k127_6148453_1 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000002331 241.0
HKD1_k127_6148453_2 LVIVD repeat - - - 0.0000000000000000000000000000000000000817 149.0
HKD1_k127_6157803_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 2166.0
HKD1_k127_6157803_1 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1615.0
HKD1_k127_6157803_10 Ribosomal protein L33 K02913 - - 0.0000000000000000002418 88.0
HKD1_k127_6157803_11 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000003521 77.0
HKD1_k127_6157803_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000006303 70.0
HKD1_k127_6157803_13 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000003702 66.0
HKD1_k127_6157803_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0 1019.0
HKD1_k127_6157803_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 361.0
HKD1_k127_6157803_4 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 301.0
HKD1_k127_6157803_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000009427 243.0
HKD1_k127_6157803_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001864 234.0
HKD1_k127_6157803_7 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000003606 216.0
HKD1_k127_6157803_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000004564 179.0
HKD1_k127_6157803_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000001449 156.0
HKD1_k127_6169783_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.145e-304 952.0
HKD1_k127_6169783_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.83e-222 702.0
HKD1_k127_6169783_10 - - - - 0.00000005374 61.0
HKD1_k127_6169783_11 Belongs to the 'phage' integrase family - - - 0.000003938 55.0
HKD1_k127_6169783_2 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 533.0
HKD1_k127_6169783_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 385.0
HKD1_k127_6169783_4 Belongs to the ribF family K07011,K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002361 275.0
HKD1_k127_6169783_5 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000002355 241.0
HKD1_k127_6169783_6 InterPro IPR014922 - - - 0.00000000000000000000000000000000000000000000000000000000009313 207.0
HKD1_k127_6169783_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000988 135.0
HKD1_k127_6169783_8 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000000001255 131.0
HKD1_k127_6169783_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000003876 104.0
HKD1_k127_6182451_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 582.0
HKD1_k127_6182451_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 357.0
HKD1_k127_6182451_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000557 233.0
HKD1_k127_6182451_3 Histidine kinase K13040 - 2.7.13.3 0.0000000000000000000000000000000000000006438 154.0
HKD1_k127_6182451_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000614 112.0
HKD1_k127_6182451_5 signal transduction histidine kinase - - - 0.000000000000000002491 90.0
HKD1_k127_6182451_6 response regulator K07714 - - 0.0000009189 52.0
HKD1_k127_6199877_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 548.0
HKD1_k127_6199877_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 516.0
HKD1_k127_6199877_10 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000001236 149.0
HKD1_k127_6199877_11 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000003739 121.0
HKD1_k127_6199877_2 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 424.0
HKD1_k127_6199877_3 PFAM Iron-containing alcohol dehydrogenase K13954,K19954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 353.0
HKD1_k127_6199877_4 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 325.0
HKD1_k127_6199877_5 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003294 284.0
HKD1_k127_6199877_6 amino acid aldolase or racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008874 254.0
HKD1_k127_6199877_7 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000001885 209.0
HKD1_k127_6199877_8 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000002568 206.0
HKD1_k127_6199877_9 CHAD domain containing protein - - - 0.00000000000000000000000000000000000002155 163.0
HKD1_k127_6207835_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 7.271e-201 644.0
HKD1_k127_6207835_1 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 395.0
HKD1_k127_6207835_10 carbohydrate transport K02025,K02027,K10118 - - 0.000000000000000000000000001158 128.0
HKD1_k127_6207835_11 L-seryl-tRNA selenium transferase - - - 0.00000004477 57.0
HKD1_k127_6207835_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 303.0
HKD1_k127_6207835_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 301.0
HKD1_k127_6207835_4 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 289.0
HKD1_k127_6207835_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001092 282.0
HKD1_k127_6207835_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001924 272.0
HKD1_k127_6207835_7 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000006893 243.0
HKD1_k127_6207835_8 Sugar ABC transporter permease K02026,K05815 - - 0.00000000000000000000000000000000000000000000000000000000000001525 225.0
HKD1_k127_6207835_9 Short-chain dehydrogenase reductase Sdr K00034,K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.47,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000003783 215.0
HKD1_k127_6220971_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001067 271.0
HKD1_k127_6220971_1 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000002908 255.0
HKD1_k127_6220971_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000005806 196.0
HKD1_k127_6221714_0 Protein of unknown function (DUF3141) - - - 0.0 1025.0
HKD1_k127_6221714_1 phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 323.0
HKD1_k127_6221714_2 DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 316.0
HKD1_k127_6221714_3 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000701 146.0
HKD1_k127_6221714_5 outer membrane efflux protein - - - 0.0000143 51.0
HKD1_k127_6223034_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 601.0
HKD1_k127_6223034_1 PFAM SAICAR synthetase K01756,K01923 - 4.3.2.2,6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000002971 252.0
HKD1_k127_6223034_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000007739 66.0
HKD1_k127_6234176_0 COG2183 Transcriptional accessory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 564.0
HKD1_k127_6242163_0 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 304.0
HKD1_k127_6242163_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002569 247.0
HKD1_k127_6242163_2 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000003226 235.0
HKD1_k127_6242163_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000001762 232.0
HKD1_k127_6242163_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000008567 58.0
HKD1_k127_6243101_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 612.0
HKD1_k127_6243101_1 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 526.0
HKD1_k127_6243101_10 Xylose isomerase-like TIM barrel K00010,K03335 - 1.1.1.18,1.1.1.369,4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000003726 270.0
HKD1_k127_6243101_11 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000001211 178.0
HKD1_k127_6243101_12 Dak2 K05879 - 2.7.1.121 0.0000000000000000000000000000000000000000009147 176.0
HKD1_k127_6243101_13 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000001384 173.0
HKD1_k127_6243101_14 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000627 153.0
HKD1_k127_6243101_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000255 132.0
HKD1_k127_6243101_16 Putative zinc-finger - - - 0.00000000000000000000000000007349 128.0
HKD1_k127_6243101_17 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000009743 111.0
HKD1_k127_6243101_18 Transporter, major facilitator family protein K08161 - - 0.0000000000000008632 90.0
HKD1_k127_6243101_2 creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 512.0
HKD1_k127_6243101_3 glucuronate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 479.0
HKD1_k127_6243101_4 Dihydroxyacetone kinase K05878 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 445.0
HKD1_k127_6243101_5 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 447.0
HKD1_k127_6243101_6 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 406.0
HKD1_k127_6243101_7 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 364.0
HKD1_k127_6243101_8 COG3959 Transketolase, N-terminal subunit K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 338.0
HKD1_k127_6243101_9 May be involved in the transport of PQQ or its precursor to the periplasm K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000001376 274.0
HKD1_k127_6254719_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 572.0
HKD1_k127_6254719_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004155 241.0
HKD1_k127_6254719_2 - - - - 0.00000000000000000000000000000000000000000001011 168.0
HKD1_k127_6254719_3 NfeD-like C-terminal, partner-binding K07403 - - 0.00000001136 67.0
HKD1_k127_6254719_4 STAS domain K03321 - - 0.0009015 46.0
HKD1_k127_6258832_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 338.0
HKD1_k127_6258832_1 Pkd domain containing protein - - - 0.00000000000002237 76.0
HKD1_k127_6258832_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000004107 57.0
HKD1_k127_6258832_3 - - - - 0.00000005855 57.0
HKD1_k127_6266864_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1278.0
HKD1_k127_6266864_1 D-galactarate dehydratase Altronate hydrolase K01685,K16850 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 524.0
HKD1_k127_6266864_10 Ion channel - - - 0.0000000000000000000000000000005972 134.0
HKD1_k127_6266864_11 SAF domain K16849 - 4.2.1.7 0.000000000000000000000000000323 117.0
HKD1_k127_6266864_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 506.0
HKD1_k127_6266864_3 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 441.0
HKD1_k127_6266864_4 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 411.0
HKD1_k127_6266864_5 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 419.0
HKD1_k127_6266864_6 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 314.0
HKD1_k127_6266864_7 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001076 284.0
HKD1_k127_6266864_8 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000002644 256.0
HKD1_k127_6271072_0 TIGRFAM Ammonium transporter K03320 - - 1.739e-221 706.0
HKD1_k127_6271072_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 591.0
HKD1_k127_6271072_2 PFAM Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 383.0
HKD1_k127_6271072_3 Signal transduction histidine kinase, nitrogen specific, NtrB K07708,K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 374.0
HKD1_k127_6271072_4 Male sterility protein K01710,K01784 - 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 323.0
HKD1_k127_6271072_5 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 315.0
HKD1_k127_6271072_6 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000004185 233.0
HKD1_k127_6271072_7 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000000000000000000000003819 159.0
HKD1_k127_6271485_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 583.0
HKD1_k127_6271485_1 Family of unknown function (DUF438) K09155 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 550.0
HKD1_k127_6271485_10 L-malate dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000008895 230.0
HKD1_k127_6271485_11 Belongs to the metal hydrolase YfiT family - - - 0.00000000000000000000000000000000000000000000000000000000000004102 219.0
HKD1_k127_6271485_12 SUF system FeS assembly protein K04488 - - 0.0000000000000000000000000000000000000000000144 164.0
HKD1_k127_6271485_13 Asp Glu hydantoin racemase - - - 0.00000000000000000000000000000000000000025 159.0
HKD1_k127_6271485_14 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000000000003372 148.0
HKD1_k127_6271485_15 Transcriptional regulator K02624,K13641 - - 0.00000000000000000000000000000000000001851 159.0
HKD1_k127_6271485_16 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000009233 146.0
HKD1_k127_6271485_17 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000001175 137.0
HKD1_k127_6271485_18 Domain of unknown function (DUF1858) - - - 0.00000000000000000000000000008728 132.0
HKD1_k127_6271485_19 membrane K07794 - - 0.000000000000000000001385 100.0
HKD1_k127_6271485_2 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 471.0
HKD1_k127_6271485_20 PFAM 4Fe-4S K14108 - - 0.0002199 50.0
HKD1_k127_6271485_21 Protein of unknown function (DUF1344) - - - 0.0004156 47.0
HKD1_k127_6271485_3 Isocitrate isopropylmalate dehydrogenase K00030,K00031,K00052 - 1.1.1.41,1.1.1.42,1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 443.0
HKD1_k127_6271485_4 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 376.0
HKD1_k127_6271485_5 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 357.0
HKD1_k127_6271485_6 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 348.0
HKD1_k127_6271485_7 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 306.0
HKD1_k127_6271485_8 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 304.0
HKD1_k127_6271485_9 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001814 271.0
HKD1_k127_6283438_0 DEAD DEAH box helicase K06877 - - 1.587e-290 928.0
HKD1_k127_6283438_1 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 538.0
HKD1_k127_6283438_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000003337 89.0
HKD1_k127_6283438_12 - - - - 0.0005583 51.0
HKD1_k127_6283438_2 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 439.0
HKD1_k127_6283438_3 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 470.0
HKD1_k127_6283438_4 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 303.0
HKD1_k127_6283438_5 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000003027 136.0
HKD1_k127_6283438_6 PFAM Uncharacterised ACR, COG1259 K08999 - - 0.000000000000000000000000000000005099 134.0
HKD1_k127_6283438_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000006864 126.0
HKD1_k127_6283438_8 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000001072 102.0
HKD1_k127_6283438_9 Molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000006246 104.0
HKD1_k127_6293776_0 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000005753 122.0
HKD1_k127_6293776_1 Receptor family ligand binding region K01999 - - 0.000000000000000000101 92.0
HKD1_k127_6293776_2 COG0782 Transcription elongation factor - - - 0.0000000000008139 75.0
HKD1_k127_6293776_3 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000001728 79.0
HKD1_k127_6306331_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1393.0
HKD1_k127_6306331_1 thiamine transport K02011 - - 6.368e-247 775.0
HKD1_k127_6306331_10 iron ion homeostasis K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 291.0
HKD1_k127_6306331_11 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 301.0
HKD1_k127_6306331_12 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001036 288.0
HKD1_k127_6306331_13 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005542 277.0
HKD1_k127_6306331_14 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000001643 212.0
HKD1_k127_6306331_15 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000001679 203.0
HKD1_k127_6306331_16 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000005756 184.0
HKD1_k127_6306331_17 Domain of unknown function (DUF4388) K03413 - - 0.00000000000000000000000000000000000000006339 168.0
HKD1_k127_6306331_18 Domain of unknown function (DUF4388) K03413 - - 0.0000000000000000000000000000000000000001697 166.0
HKD1_k127_6306331_19 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.00000000000000000000000000000000000001992 155.0
HKD1_k127_6306331_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 579.0
HKD1_k127_6306331_20 cell septum assembly - - - 0.00000000000003361 81.0
HKD1_k127_6306331_23 Chemotaxis protein CheY - - - 0.000006202 54.0
HKD1_k127_6306331_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 546.0
HKD1_k127_6306331_4 pfkB family carbohydrate kinase K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 457.0
HKD1_k127_6306331_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 441.0
HKD1_k127_6306331_6 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 421.0
HKD1_k127_6306331_7 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 377.0
HKD1_k127_6306331_8 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 373.0
HKD1_k127_6306331_9 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 346.0
HKD1_k127_6315169_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 510.0
HKD1_k127_6315169_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002356 290.0
HKD1_k127_6315169_2 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000003429 146.0
HKD1_k127_6322611_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 1.051e-207 654.0
HKD1_k127_6322611_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 490.0
HKD1_k127_6323109_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 1.408e-318 989.0
HKD1_k127_6323109_1 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 574.0
HKD1_k127_6323109_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 355.0
HKD1_k127_6323109_11 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 359.0
HKD1_k127_6323109_12 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 356.0
HKD1_k127_6323109_13 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 336.0
HKD1_k127_6323109_14 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 326.0
HKD1_k127_6323109_15 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 307.0
HKD1_k127_6323109_16 PFAM ABC transporter related K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 301.0
HKD1_k127_6323109_17 Abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 300.0
HKD1_k127_6323109_18 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 299.0
HKD1_k127_6323109_19 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002246 272.0
HKD1_k127_6323109_2 creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 506.0
HKD1_k127_6323109_20 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K08319 - 1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003068 283.0
HKD1_k127_6323109_21 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000001919 252.0
HKD1_k127_6323109_22 family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002836 263.0
HKD1_k127_6323109_23 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788,K14153 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000002123 216.0
HKD1_k127_6323109_24 Xylose isomerase-like TIM barrel K22233 - - 0.0000000000000000000000000000000000000000000000000000001746 206.0
HKD1_k127_6323109_25 Belongs to the SUA5 family K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000009684 175.0
HKD1_k127_6323109_26 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000006464 144.0
HKD1_k127_6323109_27 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000157 136.0
HKD1_k127_6323109_28 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000002631 85.0
HKD1_k127_6323109_29 oxidoreductase - - - 0.0001212 48.0
HKD1_k127_6323109_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 473.0
HKD1_k127_6323109_4 branched-chain amino acid transport system, permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 440.0
HKD1_k127_6323109_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 433.0
HKD1_k127_6323109_6 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 425.0
HKD1_k127_6323109_7 Oligopeptide/dipeptide transporter, C-terminal region K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 418.0
HKD1_k127_6323109_8 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 411.0
HKD1_k127_6323109_9 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 359.0
HKD1_k127_6332624_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 4.598e-194 610.0
HKD1_k127_6332624_1 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 398.0
HKD1_k127_6332624_2 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 371.0
HKD1_k127_6332624_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000001336 158.0
HKD1_k127_6332763_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 397.0
HKD1_k127_6332763_1 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 341.0
HKD1_k127_6332763_2 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.0000000000000000000000000000002482 129.0
HKD1_k127_6339582_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 1.815e-295 912.0
HKD1_k127_6339582_1 Amino acid permease - - - 1.636e-195 626.0
HKD1_k127_6339582_10 - - - - 0.000000000000000000006024 96.0
HKD1_k127_6339582_2 TIGRFAM Potassium uptake protein TrkH K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 511.0
HKD1_k127_6339582_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 348.0
HKD1_k127_6339582_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000006129 239.0
HKD1_k127_6339582_5 TrkA-N domain K03499,K10716 - - 0.0000000000000000000000000000000000000000000000000000001184 202.0
HKD1_k127_6339582_6 Putative NAD(P)-binding K03499 - - 0.0000000000000000000000000000000000000000000000000007504 191.0
HKD1_k127_6339582_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000003329 156.0
HKD1_k127_6339582_8 SAF K16849 - 4.2.1.7 0.00000000000000000000001372 104.0
HKD1_k127_6339582_9 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846,K16850 - 4.2.1.7,4.4.1.24 0.0000000000000000000001563 104.0
HKD1_k127_6347256_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 542.0
HKD1_k127_6347256_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 516.0
HKD1_k127_6347256_10 ABC transporter permease - - - 0.0000000000000000000000000000000000000000000000000000000000001202 226.0
HKD1_k127_6347256_11 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000000000000000000000008714 194.0
HKD1_k127_6347256_12 dna polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000001161 174.0
HKD1_k127_6347256_13 - - - - 0.00000000000000000000005898 101.0
HKD1_k127_6347256_14 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000468 97.0
HKD1_k127_6347256_15 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000004029 64.0
HKD1_k127_6347256_16 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0001686 48.0
HKD1_k127_6347256_2 GAF domain K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 502.0
HKD1_k127_6347256_3 ABC transporter substrate-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 410.0
HKD1_k127_6347256_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 304.0
HKD1_k127_6347256_5 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000817 301.0
HKD1_k127_6347256_6 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 292.0
HKD1_k127_6347256_7 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001201 290.0
HKD1_k127_6347256_8 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006424 255.0
HKD1_k127_6347256_9 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000004242 236.0
HKD1_k127_6347770_0 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 517.0
HKD1_k127_6347770_1 Pup-ligase protein K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.0000000000000000000000000000000000000000000000000000000007239 203.0
HKD1_k127_6347770_2 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000001043 194.0
HKD1_k127_6354377_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1106.0
HKD1_k127_6354377_1 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 607.0
HKD1_k127_6354377_10 PFAM NAD binding domain of 6-phosphogluconate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000004864 236.0
HKD1_k127_6354377_11 KR domain - - - 0.000000000000000000000000000000000000000000000000000002767 199.0
HKD1_k127_6354377_12 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000008126 164.0
HKD1_k127_6354377_13 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.00000000000000000000000000000005447 142.0
HKD1_k127_6354377_15 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000005779 75.0
HKD1_k127_6354377_16 EXOIII K02342 - 2.7.7.7 0.0000000001942 68.0
HKD1_k127_6354377_17 Kinase, PfkB family - - - 0.000123 48.0
HKD1_k127_6354377_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 593.0
HKD1_k127_6354377_3 ABC transporter permease K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 501.0
HKD1_k127_6354377_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 437.0
HKD1_k127_6354377_5 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 353.0
HKD1_k127_6354377_6 CBS domain containing protein K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 332.0
HKD1_k127_6354377_7 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 324.0
HKD1_k127_6354377_8 Iron ABC transporter substrate-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001392 291.0
HKD1_k127_6354377_9 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003586 266.0
HKD1_k127_6355832_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 2.548e-211 683.0
HKD1_k127_6355832_1 Alanine dehydrogenase/PNT, C-terminal domain K00259 GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009653,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030435,GO:0032502,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 499.0
HKD1_k127_6355832_10 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000441 127.0
HKD1_k127_6355832_11 - - - - 0.00000000000000000000001175 116.0
HKD1_k127_6355832_2 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 446.0
HKD1_k127_6355832_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 421.0
HKD1_k127_6355832_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 412.0
HKD1_k127_6355832_5 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 394.0
HKD1_k127_6355832_6 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 361.0
HKD1_k127_6355832_7 Carbon-nitrogen hydrolase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 355.0
HKD1_k127_6355832_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 331.0
HKD1_k127_6355832_9 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000269 225.0
HKD1_k127_635714_0 Pfam:KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 452.0
HKD1_k127_635714_1 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000001395 143.0
HKD1_k127_635714_2 FAD linked oxidase domain protein - - - 0.000000000000000000000000000006406 124.0
HKD1_k127_635714_3 Function of strongly homologous gene K08481 - - 0.0000000000001768 75.0
HKD1_k127_6367332_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 392.0
HKD1_k127_6367332_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K16049 - 1.13.11.25 0.000000000000000000000000000000000000000000000000000000000000000000003008 250.0
HKD1_k127_6367332_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000001864 172.0
HKD1_k127_6372217_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 554.0
HKD1_k127_6372217_1 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 292.0
HKD1_k127_6372217_2 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000004989 196.0
HKD1_k127_6372217_3 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000008123 132.0
HKD1_k127_6372217_5 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.000000000000135 73.0
HKD1_k127_6381867_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0006970,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009268,GO:0009409,GO:0009628,GO:0009651,GO:0009987,GO:0010467,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043021,GO:0043023,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 3.31e-289 897.0
HKD1_k127_6381867_1 Belongs to the FPP GGPP synthase family K00805,K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 321.0
HKD1_k127_6382700_0 Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 319.0
HKD1_k127_6382700_1 cytochrome complex assembly K02200,K04018,K19225,K20543,K21007 - 3.4.21.105 0.00000000000003003 81.0
HKD1_k127_6382700_2 Belongs to the 'phage' integrase family - - - 0.000000000002035 70.0
HKD1_k127_6382700_3 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000001824 64.0
HKD1_k127_6382700_4 methyltransferase K03183,K15256 - 2.1.1.163,2.1.1.201 0.0000000002075 66.0
HKD1_k127_6401007_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0 1180.0
HKD1_k127_6401007_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1008.0
HKD1_k127_6401007_10 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 339.0
HKD1_k127_6401007_11 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001155 255.0
HKD1_k127_6401007_12 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003181 242.0
HKD1_k127_6401007_13 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000003304 239.0
HKD1_k127_6401007_14 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000004176 248.0
HKD1_k127_6401007_15 phosphorelay signal transduction system K02490 - - 0.0000000000000000000000000000000000000005923 158.0
HKD1_k127_6401007_16 PLD-like domain K17717 - 3.1.4.4 0.000000000000000000000000000009462 125.0
HKD1_k127_6401007_17 NADH ubiquinone oxidoreductase subunit 5 (Chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05559 - 1.6.5.3 0.00000000000000000000002915 112.0
HKD1_k127_6401007_18 COG1320 Multisubunit Na H antiporter, MnhG subunit K05571 - - 0.000000000000000000004848 99.0
HKD1_k127_6401007_19 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000005795 92.0
HKD1_k127_6401007_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 1.001e-281 877.0
HKD1_k127_6401007_20 Na H antiporter K05567 - - 0.000000000000001156 84.0
HKD1_k127_6401007_21 multisubunit Na H antiporter MnhE subunit K05569 - - 0.0000000000001211 85.0
HKD1_k127_6401007_22 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05563 - - 0.000000000003843 70.0
HKD1_k127_6401007_23 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00000000006088 72.0
HKD1_k127_6401007_3 Amino acid permease - - - 6.958e-199 637.0
HKD1_k127_6401007_4 Potassium uptake protein, TrkH family K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 509.0
HKD1_k127_6401007_5 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05559,K05565 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 469.0
HKD1_k127_6401007_6 protein histidine kinase activity K11383 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 447.0
HKD1_k127_6401007_7 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 418.0
HKD1_k127_6401007_8 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 394.0
HKD1_k127_6401007_9 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 364.0
HKD1_k127_6401280_0 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 547.0
HKD1_k127_6401280_1 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000001041 119.0
HKD1_k127_6401280_2 Alpha amylase catalytic - - - 0.0000000000000000000000004305 106.0
HKD1_k127_6432580_0 Transposase IS66 family K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 315.0
HKD1_k127_6432580_1 L COG3436 Transposase and inactivated derivatives K07484 - - 0.00000000000000000000000000000000000000001212 169.0
HKD1_k127_6432580_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0008326 44.0
HKD1_k127_6441833_0 MULE transposase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004991 278.0
HKD1_k127_6441833_1 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000002602 189.0
HKD1_k127_6441833_2 - - - - 0.0000000000000000000000000000000000000000000000003701 183.0
HKD1_k127_6441833_3 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000000000000000000000001238 117.0
HKD1_k127_6459633_0 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 339.0
HKD1_k127_6480005_0 AAA family ATPase, CDC48 subfamily - - - 3.222e-234 747.0
HKD1_k127_6480005_1 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 580.0
HKD1_k127_6480005_10 COGs COG1144 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase delta subunit K00171,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000003387 205.0
HKD1_k127_6480005_11 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000000000003154 216.0
HKD1_k127_6480005_12 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000001985 188.0
HKD1_k127_6480005_13 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000001108 166.0
HKD1_k127_6480005_14 Transcriptional regulator K05799 - - 0.0000000000000000000000000000000000000006635 160.0
HKD1_k127_6480005_15 COGs COG1144 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase delta subunit K00171,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000001385 109.0
HKD1_k127_6480005_16 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000003774 103.0
HKD1_k127_6480005_17 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000004484 100.0
HKD1_k127_6480005_18 Thioredoxin domain - - - 0.00000000000000000003827 91.0
HKD1_k127_6480005_19 - - - - 0.00000000004751 73.0
HKD1_k127_6480005_2 protein conserved in bacteria K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 577.0
HKD1_k127_6480005_20 protein maturation K13628,K15724,K22063 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0007322 46.0
HKD1_k127_6480005_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 475.0
HKD1_k127_6480005_4 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 477.0
HKD1_k127_6480005_5 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 385.0
HKD1_k127_6480005_6 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 365.0
HKD1_k127_6480005_7 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005712 276.0
HKD1_k127_6480005_8 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004469 252.0
HKD1_k127_6480005_9 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000004494 216.0
HKD1_k127_6480563_0 B12 binding domain - - - 3.801e-236 740.0
HKD1_k127_6480563_1 membrane - - - 0.000000000000000000000000000000000000000009528 160.0
HKD1_k127_6480563_2 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.000002366 53.0
HKD1_k127_649441_0 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 484.0
HKD1_k127_6501087_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 1.506e-230 717.0
HKD1_k127_6501087_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 463.0
HKD1_k127_6501087_10 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001205 269.0
HKD1_k127_6501087_11 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946,K07123 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000006952 254.0
HKD1_k127_6501087_12 Male sterility protein K22025 - 1.1.1.410 0.0000000000000000000000000000000000000000000000000000000000000000000001208 253.0
HKD1_k127_6501087_13 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000001963 236.0
HKD1_k127_6501087_14 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000002621 238.0
HKD1_k127_6501087_15 Outer membrane lipoprotein K05807,K08309 - - 0.00000000000000000000000000000000000000000000000000000000000006626 225.0
HKD1_k127_6501087_16 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000003507 218.0
HKD1_k127_6501087_17 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000006871 218.0
HKD1_k127_6501087_18 - - - - 0.000000000000000000000000000000000000000000000000000005668 216.0
HKD1_k127_6501087_19 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000001285 193.0
HKD1_k127_6501087_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 432.0
HKD1_k127_6501087_20 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000008851 185.0
HKD1_k127_6501087_21 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000998 165.0
HKD1_k127_6501087_22 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000006523 169.0
HKD1_k127_6501087_23 response regulator, receiver K03413 - - 0.0000000000000000000000000000000000000001003 163.0
HKD1_k127_6501087_24 Haem-degrading - - - 0.0000000000000000000000000005773 120.0
HKD1_k127_6501087_27 chemotaxis K02659,K03408 - - 0.00000000000687 73.0
HKD1_k127_6501087_28 CheC-like family K03410 - - 0.000000003212 66.0
HKD1_k127_6501087_29 Sporulation and spore germination - - - 0.00000007365 63.0
HKD1_k127_6501087_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 347.0
HKD1_k127_6501087_30 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0000002415 57.0
HKD1_k127_6501087_33 - - - - 0.0003638 46.0
HKD1_k127_6501087_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 347.0
HKD1_k127_6501087_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 331.0
HKD1_k127_6501087_6 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 320.0
HKD1_k127_6501087_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 295.0
HKD1_k127_6501087_8 PFAM asparagine synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 301.0
HKD1_k127_6501087_9 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 300.0
HKD1_k127_6522139_0 Aldo/keto reductase family K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 504.0
HKD1_k127_6522139_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000009234 256.0
HKD1_k127_6522139_2 - K04517 - 1.3.1.12 0.00000000000000000000000000002788 121.0
HKD1_k127_6523095_0 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 522.0
HKD1_k127_6523095_1 Domain of unknown function (DUF4070) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 498.0
HKD1_k127_6523095_2 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 342.0
HKD1_k127_6523095_3 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001563 271.0
HKD1_k127_6523095_4 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000002271 156.0
HKD1_k127_6523095_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000007405 74.0
HKD1_k127_6523095_6 - - - - 0.0005282 52.0
HKD1_k127_6525776_0 fructose-bisphosphate aldolase K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 436.0
HKD1_k127_6525776_1 PFAM Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000003052 252.0
HKD1_k127_6525776_2 Belongs to the transketolase family K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000001171 204.0
HKD1_k127_6525776_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000003887 143.0
HKD1_k127_6525776_4 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000005137 107.0
HKD1_k127_6525776_5 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000003154 98.0
HKD1_k127_6544485_0 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 452.0
HKD1_k127_6544485_1 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 428.0
HKD1_k127_6544485_11 - - - - 0.000003837 53.0
HKD1_k127_6544485_13 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03749 - - 0.0002169 53.0
HKD1_k127_6544485_14 Belongs to the 'phage' integrase family - - - 0.0006972 44.0
HKD1_k127_6544485_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 400.0
HKD1_k127_6544485_3 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 373.0
HKD1_k127_6544485_4 Permease for cytosine/purines, uracil, thiamine, allantoin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 374.0
HKD1_k127_6544485_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 303.0
HKD1_k127_6544485_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005859 273.0
HKD1_k127_6544485_7 bacterial (prokaryotic) histone like domain K03530,K04764 - - 0.00000000000000000000000000000000000000211 148.0
HKD1_k127_6544485_8 N-terminal TM domain of oligopeptide transport permease C K15582 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000001675 115.0
HKD1_k127_6544485_9 Regulatory protein - - - 0.0000000000000000000000001043 111.0
HKD1_k127_6555366_0 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily K18983 - 5.5.1.27 0.00000000000000000000000000000000000000000000000000000000000000006186 236.0
HKD1_k127_6555366_1 conserved protein (DUF2088) - - - 0.00000000000000000000000000000000000000000000002096 177.0
HKD1_k127_6555366_2 dehydratase - - - 0.0000299 48.0
HKD1_k127_6555545_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 7.499e-256 799.0
HKD1_k127_6555545_1 PFAM Iron-containing alcohol dehydrogenase K00005,K08317 - 1.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008879 287.0
HKD1_k127_6555545_10 Thioesterase superfamily K02614 - - 0.00000000001174 71.0
HKD1_k127_6555545_11 Putative zinc-finger - - - 0.000000001104 70.0
HKD1_k127_6555545_2 binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005144 278.0
HKD1_k127_6555545_3 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000002778 255.0
HKD1_k127_6555545_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000005207 186.0
HKD1_k127_6555545_5 cyclic nucleotide binding K01420 - - 0.0000000000000000000000000000000000000000000000142 179.0
HKD1_k127_6555545_6 RNA polymerase sigma factor, sigma-70 family K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000001913 150.0
HKD1_k127_6555545_7 Major Facilitator Superfamily - - - 0.00000000000000000000000331 109.0
HKD1_k127_6555545_8 Cupin domain - - - 0.0000000000000000000003776 104.0
HKD1_k127_6555545_9 DNA polymerase alpha chain like domain - - - 0.000000000002197 78.0
HKD1_k127_6580967_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 505.0
HKD1_k127_6580967_1 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 484.0
HKD1_k127_6580967_10 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000009984 233.0
HKD1_k127_6580967_11 4Fe-4S dicluster domain K00338,K05580 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000002911 215.0
HKD1_k127_6580967_12 Carbohydrate ABC transporter membrane protein 1, CUT1 family K02025 - - 0.0000000000000000000000000000000000000000000000000000000000644 216.0
HKD1_k127_6580967_13 myo-inosose-2 dehydratase activity K06606 - 5.3.99.11 0.000000000000000000000000000000000000000000000000000000006892 209.0
HKD1_k127_6580967_14 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000024 168.0
HKD1_k127_6580967_15 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000002947 145.0
HKD1_k127_6580967_16 Rhodanese Homology Domain - - - 0.0000000000000000000000000000435 120.0
HKD1_k127_6580967_17 Extracellular solute-binding protein K02027 - - 0.0000000003381 69.0
HKD1_k127_6580967_18 H( )-stimulated, divalent metal cation uptake system - - - 0.0000000006804 72.0
HKD1_k127_6580967_2 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 358.0
HKD1_k127_6580967_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 359.0
HKD1_k127_6580967_4 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 347.0
HKD1_k127_6580967_5 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 335.0
HKD1_k127_6580967_6 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 322.0
HKD1_k127_6580967_7 4-hydroxy-2-oxoglutarate aldolase K18123 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006081,GO:0006082,GO:0006090,GO:0006520,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008700,GO:0009056,GO:0009058,GO:0009063,GO:0009436,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0016833,GO:0019470,GO:0019471,GO:0019752,GO:0031974,GO:0032787,GO:0033609,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046185,GO:0046394,GO:0046395,GO:0046487,GO:0046983,GO:0070013,GO:0071704,GO:0072329,GO:0072330,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 307.0
HKD1_k127_6580967_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001092 273.0
HKD1_k127_6580967_9 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001054 267.0
HKD1_k127_6588655_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2.844e-259 814.0
HKD1_k127_6593195_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.601e-215 678.0
HKD1_k127_6593195_1 D-galactarate dehydratase altronate hydrolase domain protein K16850 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002083 268.0
HKD1_k127_6593195_2 Enoyl-(Acyl carrier protein) reductase K00059,K18009,K19548 - 1.1.1.100,1.1.1.304,1.1.1.385,1.1.1.76 0.000000000000000000000000000000009641 137.0
HKD1_k127_6632711_0 TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001284 280.0
HKD1_k127_6632711_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000002133 218.0
HKD1_k127_6632711_2 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000002756 164.0
HKD1_k127_6632711_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000001718 57.0
HKD1_k127_6649600_0 Transposase mutator type - - - 8.65e-197 622.0
HKD1_k127_6649600_1 Transposase K01152 - - 0.00000000000000000000000001307 121.0
HKD1_k127_6649600_2 Transposase and inactivated - - - 0.000002353 55.0
HKD1_k127_6651639_0 protein conserved in bacteria K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 477.0
HKD1_k127_6651639_1 Chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 418.0
HKD1_k127_6651639_2 PFAM Alcohol dehydrogenase GroES-like K00004,K00008 - 1.1.1.14,1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 346.0
HKD1_k127_6651639_3 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 316.0
HKD1_k127_6651639_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000009131 246.0
HKD1_k127_6651639_5 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000005959 190.0
HKD1_k127_6651639_6 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000541 166.0
HKD1_k127_6651639_7 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000000000000000108 121.0
HKD1_k127_6651639_8 Tripartite tricarboxylate transporter TctB family - - - 0.00000000008043 72.0
HKD1_k127_6651639_9 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00004309 55.0
HKD1_k127_6662599_0 PFAM RNA polymerase sigma factor 54, interaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 400.0
HKD1_k127_6662599_1 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 309.0
HKD1_k127_6662599_2 - - - - 0.00000000000000000000000000000000000000000000000000000000006278 219.0
HKD1_k127_6662599_4 Protein of unknown function (DUF3604) - - - 0.00000000000000000000000000000000000000000005376 163.0
HKD1_k127_6662599_5 - - - - 0.00000000000000000000000001199 111.0
HKD1_k127_6662599_6 - - - - 0.00000000000000004044 90.0
HKD1_k127_6662599_7 Antibiotic biosynthesis monooxygenase - - - 0.000000003482 64.0
HKD1_k127_6662599_8 sigma54 specific, transcriptional regulator, Fis family - - - 0.000007822 48.0
HKD1_k127_6709115_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 404.0
HKD1_k127_6709115_1 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 325.0
HKD1_k127_6709115_2 DNA polymerase III subunit chi K02339 - 2.7.7.7 0.00000000000000008766 85.0
HKD1_k127_6710543_0 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 472.0
HKD1_k127_6710543_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 423.0
HKD1_k127_6710543_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001484 259.0
HKD1_k127_6710543_3 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000003824 94.0
HKD1_k127_6719907_0 COG3385 FOG Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 379.0
HKD1_k127_6719907_1 PFAM Rhodopirellula transposase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001358 277.0
HKD1_k127_6719907_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000009988 124.0
HKD1_k127_6719907_3 Nuclease-related domain - - - 0.00000000000000000003191 102.0
HKD1_k127_6719907_4 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 0.0000006437 54.0
HKD1_k127_68002_0 toxin-antitoxin pair type II binding - - - 0.00000000000000000000000000000001558 130.0
HKD1_k127_68002_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000003021 115.0
HKD1_k127_68002_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000003435 89.0
HKD1_k127_68002_3 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000001096 68.0
HKD1_k127_6816608_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 475.0
HKD1_k127_6816608_1 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000000000000000000001673 217.0
HKD1_k127_6816608_2 Ribosomal L32p protein family K02911 - - 0.00000000000000000000000001395 109.0
HKD1_k127_6816608_3 BlaR1 peptidase M56 - - - 0.000000000000005146 88.0
HKD1_k127_6816608_4 PAS fold - - - 0.00000000003091 76.0
HKD1_k127_6816608_5 malonyl CoA-acyl carrier protein transacylase K00645,K15327 - 2.3.1.39 0.0000000001177 62.0
HKD1_k127_6821120_0 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 393.0
HKD1_k127_6821120_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 368.0
HKD1_k127_6821120_3 response regulator K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.000000000000000000000000000000000000000000203 165.0
HKD1_k127_6821120_4 Histidine kinase - - - 0.00000000000000000000000000000000001034 158.0
HKD1_k127_6821120_5 PFAM GPR1 FUN34 yaaH family K07034 - - 0.00000001864 59.0
HKD1_k127_6821120_6 PFAM GPR1 FUN34 yaaH family K07034 - - 0.00001094 49.0
HKD1_k127_6840925_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 576.0
HKD1_k127_6840925_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001258 275.0
HKD1_k127_6847802_0 Major facilitator superfamily - - - 0.00000000000000000000000006705 113.0
HKD1_k127_6847802_1 GtrA-like protein - - - 0.0000000000000000000004255 102.0
HKD1_k127_6847802_2 ABC transporter, ATP-binding protein K01990 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0022857,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000001357 52.0
HKD1_k127_6860614_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 4.738e-217 683.0
HKD1_k127_6860614_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 574.0
HKD1_k127_6860614_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 433.0
HKD1_k127_6860614_3 Ni2 binding GTPase involved in regulation of expression and maturation of urease and hydrogenase K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 336.0
HKD1_k127_6860614_4 PFAM NADH ubiquinone oxidoreductase, 20 K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 342.0
HKD1_k127_6860614_5 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000004796 191.0
HKD1_k127_6860614_6 - - - - 0.00000007631 61.0
HKD1_k127_6862552_0 methyltransferase K20421 - 2.1.1.303 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 527.0
HKD1_k127_6905809_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000006876 181.0
HKD1_k127_6905809_1 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000005574 146.0
HKD1_k127_6905809_2 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000000000000000001787 102.0
HKD1_k127_6905809_3 Rubrerythrin - - - 0.0000000004504 70.0
HKD1_k127_6911788_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 588.0
HKD1_k127_6911788_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K02805 GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 531.0
HKD1_k127_6911788_10 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000402 209.0
HKD1_k127_6911788_11 PFAM Glycosyl transferase family 4 K02851,K13007 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000005608 201.0
HKD1_k127_6911788_12 acetyltransferase - - - 0.0000000000000000000000000000000000000002699 161.0
HKD1_k127_6911788_13 Methyltransferase domain - - - 0.0000000000001899 76.0
HKD1_k127_6911788_14 Nodulation protein S (NodS) - - - 0.0000000004093 63.0
HKD1_k127_6911788_15 - - - - 0.00001458 57.0
HKD1_k127_6911788_16 Methyltransferase domain - - - 0.0001298 51.0
HKD1_k127_6911788_17 Involved in the TonB-independent uptake of proteins K03641 - - 0.0001728 53.0
HKD1_k127_6911788_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007658 421.0
HKD1_k127_6911788_3 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 415.0
HKD1_k127_6911788_4 PFAM Glycosyl transferase, group 1 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 391.0
HKD1_k127_6911788_5 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 366.0
HKD1_k127_6911788_6 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 337.0
HKD1_k127_6911788_7 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007136 281.0
HKD1_k127_6911788_8 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001682 283.0
HKD1_k127_6911788_9 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000115 226.0
HKD1_k127_6990691_0 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 471.0
HKD1_k127_6990691_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000624 243.0
HKD1_k127_6990691_2 FemAB family - - - 0.000000000000000000000000000000000000000000000000000000000000008676 228.0
HKD1_k127_6990691_3 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000002002 179.0
HKD1_k127_6990691_4 Domain of Unknown Function (DUF350) - - - 0.0000000000000000000000000001518 126.0
HKD1_k127_6992558_0 ABC transporter permease K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 517.0
HKD1_k127_6992558_1 ATPases associated with a variety of cellular activities K02010,K11072 - 3.6.3.30,3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 336.0
HKD1_k127_6992558_2 ABC transporter permease K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004505 276.0
HKD1_k127_6992558_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000004981 230.0
HKD1_k127_6992558_4 glycerophosphodiester transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000006321 220.0
HKD1_k127_7020791_0 PFAM Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 377.0
HKD1_k127_7020791_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 297.0
HKD1_k127_7020791_3 Aminotransferase class I and II - - - 0.000000000000000000000007615 108.0
HKD1_k127_7034320_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 2.534e-210 664.0
HKD1_k127_7034320_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 556.0
HKD1_k127_7034320_10 DinB family - - - 0.000000000000000000000000000000000000000000311 168.0
HKD1_k127_7034320_11 - - - - 0.00000000000000000000000000000000000002069 147.0
HKD1_k127_7034320_12 Ferredoxin - - - 0.00000000000000000000000000004242 128.0
HKD1_k127_7034320_13 Lecithin:cholesterol acyltransferase - - - 0.00000000000000000000004663 113.0
HKD1_k127_7034320_2 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 449.0
HKD1_k127_7034320_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 310.0
HKD1_k127_7034320_4 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005852 287.0
HKD1_k127_7034320_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006643 284.0
HKD1_k127_7034320_6 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001249 272.0
HKD1_k127_7034320_7 COG0559 Branched-chain amino acid ABC-type transport system, permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007255 265.0
HKD1_k127_7034320_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001267 261.0
HKD1_k127_7034320_9 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000002371 227.0
HKD1_k127_7042984_0 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006384 266.0
HKD1_k127_7042984_1 Protein of unknown function (DUF1810) - - - 0.0000009881 50.0
HKD1_k127_70470_0 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 340.0
HKD1_k127_70470_1 His Kinase A (phosphoacceptor) domain K02484,K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000601 211.0
HKD1_k127_7068447_0 Tripartite tricarboxylate transporter TctA family - - - 2.078e-228 717.0
HKD1_k127_7068447_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 380.0
HKD1_k127_7068447_2 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000003342 117.0
HKD1_k127_7068655_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1399.0
HKD1_k127_7068655_1 Large extracellular alpha-helical protein K06894 - - 8.122e-216 699.0
HKD1_k127_7068655_10 17 kDa outer membrane surface antigen - - - 0.000000000000000000000000000000000006339 142.0
HKD1_k127_7068655_11 THIoesterase K18700 - 3.1.2.29 0.000000000000000000000002592 110.0
HKD1_k127_7068655_12 Protein of unknown function (DUF2892) - - - 0.000000000000000002741 86.0
HKD1_k127_7068655_13 EF-hand domain pair - - - 0.0000000000002137 77.0
HKD1_k127_7068655_2 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 393.0
HKD1_k127_7068655_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 372.0
HKD1_k127_7068655_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002114 282.0
HKD1_k127_7068655_5 beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000004782 260.0
HKD1_k127_7068655_6 MlaD protein K06192 - - 0.000000000000000000000000000000000000000000000000000006237 204.0
HKD1_k127_7068655_7 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000000000006931 162.0
HKD1_k127_7068655_8 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0000000000000000000000000000000000006924 148.0
HKD1_k127_7068655_9 Outer membrane efflux protein - - - 0.000000000000000000000000000000000001461 143.0
HKD1_k127_7089558_0 Dienelactone hydrolase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 351.0
HKD1_k127_7089558_1 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000001624 221.0
HKD1_k127_7089558_2 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000002149 107.0
HKD1_k127_7097510_0 exo-alpha-(2->6)-sialidase activity - - - 5.603e-208 697.0
HKD1_k127_7097510_1 Resolvase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 557.0
HKD1_k127_7097510_10 Family of unknown function (DUF5372) - - - 0.0000000000000000000001677 104.0
HKD1_k127_7097510_11 transposition K07497 - - 0.00000000000000000001129 93.0
HKD1_k127_7097510_12 Resolvase domain - - - 0.00000000000000002147 85.0
HKD1_k127_7097510_13 Belongs to the glycosyl hydrolase 31 family K01187,K18820 GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758,GO:0033825,GO:0046527 2.4.1.161,3.2.1.20 0.0000001034 66.0
HKD1_k127_7097510_14 COG3316 Transposase and inactivated derivatives - - - 0.0000001066 53.0
HKD1_k127_7097510_2 recombinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 475.0
HKD1_k127_7097510_3 Thermolysin metallopeptidase, alpha-helical domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 388.0
HKD1_k127_7097510_4 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000339 256.0
HKD1_k127_7097510_5 Resolvase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004408 222.0
HKD1_k127_7097510_6 Winged helix-turn helix K13771 - - 0.0000000000000000000000000000000054 133.0
HKD1_k127_7097510_7 ATPase involved in DNA repair - - - 0.00000000000000000000000000000001432 149.0
HKD1_k127_7097510_8 PFAM transposase IS3 IS911 family protein - - - 0.0000000000000000000000007696 106.0
HKD1_k127_7097510_9 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000000000000000000000001781 107.0
HKD1_k127_7101711_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 443.0
HKD1_k127_7101711_1 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000004582 185.0
HKD1_k127_7107254_0 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000006371 229.0
HKD1_k127_7107254_1 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000001361 208.0
HKD1_k127_7107254_2 DGC domain - - - 0.00000000000000000000000000000000000000000469 162.0
HKD1_k127_7107254_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000005728 132.0
HKD1_k127_7107254_4 Cupin domain - - - 0.00000000000000000121 91.0
HKD1_k127_7107254_5 ABC transporter substrate binding protein K01989 - - 0.000000001158 67.0
HKD1_k127_7107258_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007278 278.0
HKD1_k127_7107258_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007477 265.0
HKD1_k127_7107258_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001682 257.0
HKD1_k127_7107258_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000002083 160.0
HKD1_k127_7107258_4 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000005728 132.0
HKD1_k127_7118183_0 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 334.0
HKD1_k127_7118183_1 - - - - 0.000000000000000000000000000000000000000000000000000006244 199.0
HKD1_k127_7118183_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000002371 168.0
HKD1_k127_7118183_3 ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000177 117.0
HKD1_k127_7118183_4 SnoaL-like polyketide cyclase - - - 0.0000000000000007912 82.0
HKD1_k127_7118183_5 SnoaL-like polyketide cyclase - - - 0.00000000000005671 79.0
HKD1_k127_7118183_7 ATPase (AAA superfamily K07133 - - 0.0000355 51.0
HKD1_k127_7124917_0 Acetyl-CoA hydrolase/transferase N-terminal domain K01067,K18118 - 2.8.3.18,3.1.2.1 1.226e-255 796.0
HKD1_k127_7124917_1 mannitol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 516.0
HKD1_k127_7124917_2 carbohydrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 310.0
HKD1_k127_7124917_3 Amidohydrolase family - - - 0.000000000000000000000000072 115.0
HKD1_k127_7124917_4 - - - - 0.000000000000122 77.0
HKD1_k127_7124917_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000003 73.0
HKD1_k127_7125950_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00928,K12524 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 622.0
HKD1_k127_7125950_1 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 539.0
HKD1_k127_7125950_10 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 319.0
HKD1_k127_7125950_11 RNA pseudouridylate synthase K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000002415 244.0
HKD1_k127_7125950_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000001534 242.0
HKD1_k127_7125950_13 Prephenate dehydrogenase K00210,K00220,K00800,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43,2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000003099 236.0
HKD1_k127_7125950_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000001224 214.0
HKD1_k127_7125950_15 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000000001486 209.0
HKD1_k127_7125950_16 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000001687 207.0
HKD1_k127_7125950_17 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000002236 198.0
HKD1_k127_7125950_18 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K01007,K03977,K08591,K22278 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15,2.7.9.2,3.5.1.104 0.0000000000000000000000000000000000000000000000000002984 191.0
HKD1_k127_7125950_19 HEPN domain - - - 0.00000000000000000000000000000000000000000000000002533 183.0
HKD1_k127_7125950_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 444.0
HKD1_k127_7125950_20 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000000001309 177.0
HKD1_k127_7125950_21 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000006597 172.0
HKD1_k127_7125950_22 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000116 166.0
HKD1_k127_7125950_23 lipopolysaccharide binding K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.000000000000000000000000000000000000004305 152.0
HKD1_k127_7125950_24 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000001415 136.0
HKD1_k127_7125950_25 Phosphotransferase System K11189 - - 0.0000000000000000000001334 100.0
HKD1_k127_7125950_26 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.000000000001018 78.0
HKD1_k127_7125950_27 transcriptional - - - 0.0000001994 57.0
HKD1_k127_7125950_28 Lipopolysaccharide-assembly, LptC-related - - - 0.0000003273 61.0
HKD1_k127_7125950_3 Prephenate dehydratase K00661,K01713,K04092,K04093,K04516,K04518,K14170,K14187 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,2.3.1.79,4.2.1.51,4.2.1.91,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 438.0
HKD1_k127_7125950_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 402.0
HKD1_k127_7125950_5 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 359.0
HKD1_k127_7125950_6 PFAM Alcohol dehydrogenase, zinc-binding K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 360.0
HKD1_k127_7125950_7 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 361.0
HKD1_k127_7125950_8 P-loop ATPase protein family K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 346.0
HKD1_k127_7125950_9 Fe-S oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 340.0
HKD1_k127_7149518_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 422.0
HKD1_k127_7149518_1 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000001863 187.0
HKD1_k127_7149518_2 spermidine putrescine K02054 - - 0.000000000000000000000000000000000000000007532 161.0
HKD1_k127_7149518_3 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000002089 76.0
HKD1_k127_7149518_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000005512 79.0
HKD1_k127_7150817_0 peptidyl-tyrosine sulfation - - - 0.000000011 65.0
HKD1_k127_7150817_1 His Kinase A (phosphoacceptor) domain - - - 0.00000001159 64.0
HKD1_k127_7153363_0 General secretory system II, protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 583.0
HKD1_k127_7153363_1 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 298.0
HKD1_k127_7153363_10 Type II secretory pathway, pseudopilin - - - 0.0001112 51.0
HKD1_k127_7153363_2 type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 306.0
HKD1_k127_7153363_3 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000006665 142.0
HKD1_k127_7153363_4 General secretion pathway K02456 - - 0.00000000000000000000000000003912 126.0
HKD1_k127_7153363_5 Pilus assembly protein, PilO K02664 - - 0.000000000008137 74.0
HKD1_k127_7153363_6 Pilus assembly protein - - - 0.00000000001509 77.0
HKD1_k127_7153363_7 PFAM Fimbrial assembly family protein K02663 - - 0.00000000003517 74.0
HKD1_k127_7153363_9 Type II secretory pathway, pseudopilin - - - 0.000001164 51.0
HKD1_k127_7154220_0 Protein of unknown function (DUF1254) - - - 2.286e-268 831.0
HKD1_k127_7154220_1 PFAM peptidase U34 dipeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 329.0
HKD1_k127_7157112_0 Transglycosylase - - - 2.789e-231 752.0
HKD1_k127_7157112_1 Pirin C-terminal cupin domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 542.0
HKD1_k127_7157112_10 Tripartite tricarboxylate transporter TctB family - - - 0.0003352 48.0
HKD1_k127_7157112_2 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002799 294.0
HKD1_k127_7157112_3 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000007436 214.0
HKD1_k127_7157112_4 Protein of unknown function (DUF4239) - - - 0.00000000000000000000000000000000000000000000000000000001494 207.0
HKD1_k127_7157112_5 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000008204 205.0
HKD1_k127_7157112_6 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000062 176.0
HKD1_k127_7157112_7 DinB superfamily - - - 0.000000000000000000000000000002516 125.0
HKD1_k127_7157112_8 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000023 129.0
HKD1_k127_7157112_9 - - - - 0.0000000000000000009852 92.0
HKD1_k127_7175286_0 Glycogen debranching enzyme - - - 0.0 1356.0
HKD1_k127_7175286_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000005015 220.0
HKD1_k127_7182409_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 465.0
HKD1_k127_7182409_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 405.0
HKD1_k127_7182409_2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 360.0
HKD1_k127_7182409_3 TIGRFAM RHS repeat-associated core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 317.0
HKD1_k127_7182409_4 Enoyl-CoA hydratase/isomerase K13767 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000355 262.0
HKD1_k127_7182409_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000001141 218.0
HKD1_k127_7182409_6 cellulose binding K01179 - 3.2.1.4 0.0000000000000000009884 101.0
HKD1_k127_7182409_8 Amidohydrolase K07045 - - 0.000638 51.0
HKD1_k127_7191065_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1079.0
HKD1_k127_7191065_1 Belongs to the carbamoyltransferase HypF family K04656 - - 1.979e-287 912.0
HKD1_k127_7191065_10 Nickel-dependent hydrogenase K15830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 302.0
HKD1_k127_7191065_11 solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000178 268.0
HKD1_k127_7191065_12 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001874 260.0
HKD1_k127_7191065_13 PFAM Silent information regulator protein Sir2 K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005998 250.0
HKD1_k127_7191065_14 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000404 223.0
HKD1_k127_7191065_15 Zinc-binding dehydrogenase K13979 - - 0.00000000000000000000000000000000000000000000000000000000001002 207.0
HKD1_k127_7191065_16 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000008013 211.0
HKD1_k127_7191065_17 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000005246 202.0
HKD1_k127_7191065_18 response regulator - - - 0.00000000000000000000000000000000002194 154.0
HKD1_k127_7191065_19 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000002609 142.0
HKD1_k127_7191065_2 PFAM Glu Leu Phe Val dehydrogenase K15371 - 1.4.1.2 3.967e-250 782.0
HKD1_k127_7191065_20 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.0000000000000000000000000000001004 136.0
HKD1_k127_7191065_21 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000002374 114.0
HKD1_k127_7191065_22 PFAM CheW domain protein K03408 - - 0.000000000000000000749 93.0
HKD1_k127_7191065_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000008568 70.0
HKD1_k127_7191065_24 Two component signalling adaptor domain K03408 - - 0.0000000294 63.0
HKD1_k127_7191065_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 6.179e-222 702.0
HKD1_k127_7191065_4 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 4.37e-213 666.0
HKD1_k127_7191065_5 hydrogenase expression formation protein K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 578.0
HKD1_k127_7191065_6 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 480.0
HKD1_k127_7191065_7 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 427.0
HKD1_k127_7191065_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 368.0
HKD1_k127_7191065_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 329.0
HKD1_k127_7202074_0 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001926 263.0
HKD1_k127_7202074_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003708 243.0
HKD1_k127_7202074_2 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000001212 199.0
HKD1_k127_7203645_0 Transposase IS66 family K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 334.0
HKD1_k127_7203645_1 COG3335 Transposase and inactivated derivatives K07494 - - 0.00000000000000000000000000000000000000000000000000000000006175 209.0
HKD1_k127_7203645_2 COG3335 Transposase and inactivated derivatives K07494 - - 0.0000000000000000000000000000000000009947 153.0
HKD1_k127_7205211_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 339.0
HKD1_k127_7205211_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 302.0
HKD1_k127_7205211_2 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000004481 219.0
HKD1_k127_7205211_3 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000004123 209.0
HKD1_k127_7205211_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000000000000000000000000000000000000000001169 201.0
HKD1_k127_7205211_5 COG4520 Surface antigen - - - 0.00000000000000000000000000000000000004049 149.0
HKD1_k127_7205211_6 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.0008077 46.0
HKD1_k127_7206887_0 L-lactate permease K02550,K03303 - - 2.471e-219 696.0
HKD1_k127_7206887_1 lactate/malate dehydrogenase, alpha/beta C-terminal domain K00016 - 1.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 364.0
HKD1_k127_7206887_10 PAS fold - - - 0.0000000001042 70.0
HKD1_k127_7206887_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 340.0
HKD1_k127_7206887_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001129 267.0
HKD1_k127_7206887_4 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000009599 229.0
HKD1_k127_7206887_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000726 214.0
HKD1_k127_7206887_6 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000000000000000000000003315 183.0
HKD1_k127_7206887_7 Haem-binding domain - - - 0.00000000000000000000000000000000000001414 149.0
HKD1_k127_7206887_8 PFAM response regulator receiver K22010 - - 0.00000000000000000000000001227 119.0
HKD1_k127_7206887_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286,K12976,K16079 - - 0.00000000000001473 82.0
HKD1_k127_720935_0 Phage Terminase - - - 0.000000000007201 69.0
HKD1_k127_7210437_0 CBS domain containing protein K00974 - 2.7.7.72 1.807e-246 789.0
HKD1_k127_7210437_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 494.0
HKD1_k127_7210437_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 393.0
HKD1_k127_7210437_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 367.0
HKD1_k127_7210437_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 318.0
HKD1_k127_7210437_5 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000006171 211.0
HKD1_k127_7210437_6 Virulence factor BrkB K07058 - - 0.0000000000001107 81.0
HKD1_k127_7210437_7 Lipopolysaccharide assembly protein A domain - - - 0.000001856 54.0
HKD1_k127_7211844_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 599.0
HKD1_k127_7211844_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 462.0
HKD1_k127_7211844_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0002615 48.0
HKD1_k127_7253193_0 - K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 374.0
HKD1_k127_7253193_1 Phage integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 286.0
HKD1_k127_7253193_2 Plasmid pRiA4b ORF-3-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004034 261.0
HKD1_k127_7276751_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 8.465e-260 835.0
HKD1_k127_7276751_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 3.763e-247 808.0
HKD1_k127_7276751_10 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 352.0
HKD1_k127_7276751_11 3-oxoacyl-[acyl-carrier-protein] synthase activity K05551,K09458,K14667 - 2.3.1.179,2.3.1.235,2.3.1.260 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 351.0
HKD1_k127_7276751_12 4Fe-4S dicluster domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 333.0
HKD1_k127_7276751_13 PFAM FAD linked oxidase domain protein K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003181 295.0
HKD1_k127_7276751_14 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003307 283.0
HKD1_k127_7276751_15 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001185 278.0
HKD1_k127_7276751_17 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000324 239.0
HKD1_k127_7276751_18 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000158 228.0
HKD1_k127_7276751_2 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 569.0
HKD1_k127_7276751_20 conserved protein UCP033924 - - - 0.00000000000000000000000000000000000000000002618 170.0
HKD1_k127_7276751_21 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03574 - 3.6.1.55 0.000000000000000000000000000000001545 139.0
HKD1_k127_7276751_22 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000001438 120.0
HKD1_k127_7276751_23 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000007597 86.0
HKD1_k127_7276751_24 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 0.000000000000003359 87.0
HKD1_k127_7276751_25 Beta-ketoacyl synthase, N-terminal domain K09458 - 2.3.1.179 0.0000000003266 72.0
HKD1_k127_7276751_3 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 533.0
HKD1_k127_7276751_4 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 523.0
HKD1_k127_7276751_5 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 444.0
HKD1_k127_7276751_6 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 439.0
HKD1_k127_7276751_7 radical SAM domain protein K07011,K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 417.0
HKD1_k127_7276751_8 COG1233 Phytoene dehydrogenase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 378.0
HKD1_k127_7276751_9 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 357.0
HKD1_k127_7299846_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 6.801e-283 884.0
HKD1_k127_7299846_1 Histidine kinase-like ATPases - - - 1.021e-274 884.0
HKD1_k127_7299846_10 Thioredoxin-like K02199,K03671 - - 0.000000000000000000000000000000000000000000000000000000000000000009775 230.0
HKD1_k127_7299846_11 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000126 241.0
HKD1_k127_7299846_12 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.0000000000000000000000000000000000000000000000000000000006605 207.0
HKD1_k127_7299846_13 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000002467 199.0
HKD1_k127_7299846_14 PFAM Cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000008055 173.0
HKD1_k127_7299846_15 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000004401 149.0
HKD1_k127_7299846_16 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000002895 162.0
HKD1_k127_7299846_17 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000009735 136.0
HKD1_k127_7299846_18 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000000000000000000000005784 140.0
HKD1_k127_7299846_19 subunit of a heme lyase K02198,K02200 - - 0.00000000000000000000000000001032 124.0
HKD1_k127_7299846_2 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 569.0
HKD1_k127_7299846_20 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000122 135.0
HKD1_k127_7299846_21 HWE histidine kinase - - - 0.000000000000000000001302 111.0
HKD1_k127_7299846_22 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000002096 68.0
HKD1_k127_7299846_24 peroxiredoxin activity K03564 - 1.11.1.15 0.0005221 45.0
HKD1_k127_7299846_3 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006759 434.0
HKD1_k127_7299846_4 Transcriptional regulator (AsnC family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 381.0
HKD1_k127_7299846_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 352.0
HKD1_k127_7299846_6 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 310.0
HKD1_k127_7299846_7 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001239 304.0
HKD1_k127_7299846_8 HpcH/HpaI aldolase/citrate lyase family K02510,K12660 - 4.1.2.52,4.1.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001814 273.0
HKD1_k127_7299846_9 metal-dependent phosphoesterases (PHP family) K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000004741 240.0
HKD1_k127_7309079_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 8.231e-284 878.0
HKD1_k127_7309079_1 ABC transporter K02021,K06147,K11085 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 3.652e-210 667.0
HKD1_k127_7309079_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 488.0
HKD1_k127_7309079_3 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 363.0
HKD1_k127_7309079_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000004396 265.0
HKD1_k127_7309079_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000003474 83.0
HKD1_k127_7317135_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 301.0
HKD1_k127_7318035_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 586.0
HKD1_k127_7318035_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000004871 92.0
HKD1_k127_7318111_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001358 264.0
HKD1_k127_7318111_1 toxin-antitoxin pair type II binding - - - 0.000000000000000000000000000000009444 131.0
HKD1_k127_7318111_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000001256 83.0
HKD1_k127_7318111_3 Addiction module toxin, RelE StbE family - - - 0.0000000002407 64.0
HKD1_k127_7330135_0 isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 481.0
HKD1_k127_7330135_1 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006756 266.0
HKD1_k127_7330135_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500,K11392,K21970 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,2.1.1.178 0.00000000000000000000000000000000000000000000000000000000000000000003703 241.0
HKD1_k127_7330135_3 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000001954 159.0
HKD1_k127_7330135_4 PASTA K08884,K12132 - 2.7.11.1 0.00000000000000004394 92.0
HKD1_k127_7337619_0 COG0666 FOG Ankyrin repeat - - - 0.000000000000000000000000000000000000397 153.0
HKD1_k127_7337619_1 PFAM Nitroreductase - - - 0.000000000000000000000000001223 121.0
HKD1_k127_7337619_2 Major Facilitator Superfamily - - - 0.0000000000000000003673 100.0
HKD1_k127_7337619_3 ankyrin repeat K21440 - - 0.0000004265 61.0
HKD1_k127_7337619_4 S1/P1 Nuclease - - - 0.00004106 56.0
HKD1_k127_7355842_0 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 407.0
HKD1_k127_7355842_1 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000001012 215.0
HKD1_k127_7355842_2 methyltransferase activity - - - 0.0000000000000000000000000000000000000005034 164.0
HKD1_k127_7355842_3 Protein of unknown function (DUF429) K03574 - 3.6.1.55 0.000000000000000000000000000000000000004244 161.0
HKD1_k127_7355842_4 Protein of unknown function (DUF1328) - - - 0.00000000000001774 74.0
HKD1_k127_7355842_5 Integrase core domain - - - 0.0000003984 57.0
HKD1_k127_7355842_6 BON domain K04065 - - 0.00003115 53.0
HKD1_k127_7355842_7 FCD - - - 0.000194 46.0
HKD1_k127_735846_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 1.77e-311 985.0
HKD1_k127_735846_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 5.859e-244 760.0
HKD1_k127_735846_10 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 326.0
HKD1_k127_735846_11 LamB/YcsF family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 316.0
HKD1_k127_735846_12 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008812 331.0
HKD1_k127_735846_13 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 314.0
HKD1_k127_735846_14 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 297.0
HKD1_k127_735846_15 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001407 295.0
HKD1_k127_735846_16 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003811 283.0
HKD1_k127_735846_17 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006708 276.0
HKD1_k127_735846_18 pfam abc K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001079 268.0
HKD1_k127_735846_19 PFAM major facilitator superfamily MFS_1 K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001573 261.0
HKD1_k127_735846_2 Protein tyrosine kinase - - - 3.367e-206 668.0
HKD1_k127_735846_20 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004616 252.0
HKD1_k127_735846_21 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000004289 244.0
HKD1_k127_735846_22 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000005457 241.0
HKD1_k127_735846_23 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000001068 220.0
HKD1_k127_735846_24 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000007226 214.0
HKD1_k127_735846_25 Nitrogen regulatory protein P-II K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000002737 201.0
HKD1_k127_735846_26 transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000334 182.0
HKD1_k127_735846_28 Domain of unknown function (DUF4392) K22210 - 4.2.1.48 0.0000000000000000000000000000000000000008467 161.0
HKD1_k127_735846_29 Response regulator receiver domain - - - 0.0000000000000000000000000000005599 127.0
HKD1_k127_735846_3 PFAM Type II secretion system protein E - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 519.0
HKD1_k127_735846_30 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000000000008426 128.0
HKD1_k127_735846_31 4Fe-4S dicluster domain K03522,K05337 - - 0.000000000000000000000000001917 119.0
HKD1_k127_735846_32 Rhodanese Homology Domain - - - 0.000000000000000000000002283 105.0
HKD1_k127_735846_33 Protein of unknown function (DUF1232) - - - 0.000000000000000000000004391 109.0
HKD1_k127_735846_34 nucleotidyltransferase activity K07075 - - 0.000000000000000000002087 97.0
HKD1_k127_735846_35 Domain of unknown function (DUF296) K06934 - - 0.0000000000000000008303 93.0
HKD1_k127_735846_36 cobalt ion transport K02009 - - 0.0000000000000000009234 97.0
HKD1_k127_735846_38 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000003601 87.0
HKD1_k127_735846_4 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 519.0
HKD1_k127_735846_40 Pfam SEC-C motif - - - 0.000000000001263 80.0
HKD1_k127_735846_41 PFAM nitrogen-fixing NifU - - - 0.000000002875 59.0
HKD1_k127_735846_5 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 465.0
HKD1_k127_735846_6 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 425.0
HKD1_k127_735846_7 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 384.0
HKD1_k127_735846_8 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 397.0
HKD1_k127_735846_9 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 327.0
HKD1_k127_7367721_0 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 538.0
HKD1_k127_7367721_1 Transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 501.0
HKD1_k127_7367721_2 Chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 431.0
HKD1_k127_7367721_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 407.0
HKD1_k127_7367721_4 PFAM Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008969 243.0
HKD1_k127_7367721_5 - - - - 0.0000000000000000000000001922 109.0
HKD1_k127_7367721_6 SNARE associated Golgi protein - - - 0.00000000000000004523 85.0
HKD1_k127_7367721_7 Mechanosensitive ion channel - - - 0.000000000002248 69.0
HKD1_k127_7386575_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 366.0
HKD1_k127_7386575_1 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000000000000000000000000003241 122.0
HKD1_k127_7386575_3 - - - - 0.0000006047 52.0
HKD1_k127_7413599_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 548.0
HKD1_k127_7413599_1 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 471.0
HKD1_k127_7413599_10 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000008127 236.0
HKD1_k127_7413599_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000003063 201.0
HKD1_k127_7413599_12 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000009755 174.0
HKD1_k127_7413599_13 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000004251 168.0
HKD1_k127_7413599_14 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000002713 162.0
HKD1_k127_7413599_15 Cupin - - - 0.000000000000000000000000000000004971 133.0
HKD1_k127_7413599_16 Chromate transporter K07240 - - 0.0000000000000000000000000000002132 130.0
HKD1_k127_7413599_17 Nuclease-related domain K07460 - - 0.000000000000000000000000000002514 127.0
HKD1_k127_7413599_18 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000002793 119.0
HKD1_k127_7413599_19 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.00000000000000000000004721 101.0
HKD1_k127_7413599_2 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 413.0
HKD1_k127_7413599_20 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000001395 101.0
HKD1_k127_7413599_21 Trap-type c4-dicarboxylate transport system, small permease component K11689,K21394 - - 0.00000000000003811 78.0
HKD1_k127_7413599_22 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000003064 60.0
HKD1_k127_7413599_23 SNARE associated Golgi protein - - - 0.000001888 50.0
HKD1_k127_7413599_3 Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 382.0
HKD1_k127_7413599_4 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 363.0
HKD1_k127_7413599_5 Molybdate transporter of MFS superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 327.0
HKD1_k127_7413599_6 Belongs to the RNA methyltransferase TrmD family K00554,K01770 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 286.0
HKD1_k127_7413599_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001783 296.0
HKD1_k127_7413599_8 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007329 273.0
HKD1_k127_7413599_9 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002556 265.0
HKD1_k127_7416000_0 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 370.0
HKD1_k127_7416000_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000001378 89.0
HKD1_k127_7417060_0 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 458.0
HKD1_k127_7417060_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 405.0
HKD1_k127_7417060_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 357.0
HKD1_k127_7417060_3 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 295.0
HKD1_k127_7417060_4 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000005767 173.0
HKD1_k127_7417060_5 ThiS family K03636 - - 0.00006766 51.0
HKD1_k127_7419872_0 Belongs to the aldehyde dehydrogenase family K13821 - 1.2.1.88,1.5.5.2 2.948e-279 893.0
HKD1_k127_7419872_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 9.987e-249 786.0
HKD1_k127_7419872_10 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000221 232.0
HKD1_k127_7419872_11 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000002069 222.0
HKD1_k127_7419872_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K03336 - 3.7.1.22 1.555e-248 784.0
HKD1_k127_7419872_3 Aminotransferase class-III K00833,K03851,K12256,K15372 - 2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 578.0
HKD1_k127_7419872_4 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 503.0
HKD1_k127_7419872_5 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 388.0
HKD1_k127_7419872_6 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 389.0
HKD1_k127_7419872_7 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 379.0
HKD1_k127_7419872_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 362.0
HKD1_k127_7419872_9 Ribosomal RNA adenine dimethylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002197 254.0
HKD1_k127_7456271_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 571.0
HKD1_k127_7459601_0 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 310.0
HKD1_k127_7459601_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 300.0
HKD1_k127_7469050_0 C-terminal region of aryl-sulfatase - - - 0.0 1028.0
HKD1_k127_7469050_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 514.0
HKD1_k127_7469050_10 Transposase K07486 - - 0.000001105 51.0
HKD1_k127_7469050_11 helix_turn_helix, Lux Regulon - - - 0.00002134 54.0
HKD1_k127_7469050_2 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 484.0
HKD1_k127_7469050_3 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 321.0
HKD1_k127_7469050_4 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008888 252.0
HKD1_k127_7469050_5 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000004495 227.0
HKD1_k127_7469050_6 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000000000000000000000000002621 160.0
HKD1_k127_7469050_7 Transposase - - - 0.0000000000000000002023 93.0
HKD1_k127_7469050_9 - - - - 0.000000005472 61.0
HKD1_k127_7475186_0 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 395.0
HKD1_k127_7475186_1 Beta-lactamase enzyme family K01286,K07258,K07262 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001125 276.0
HKD1_k127_7475186_2 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000001488 115.0
HKD1_k127_7475186_3 copG family - - - 0.0000000000000000000000001341 112.0
HKD1_k127_7475186_4 Protein of unknown function (DUF2283) - - - 0.000000000002635 73.0
HKD1_k127_7483886_0 GPR1/FUN34/yaaH family K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002668 269.0
HKD1_k127_7483886_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000005873 187.0
HKD1_k127_7483886_2 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000002372 175.0
HKD1_k127_7495103_0 Ornithine cyclodeaminase/mu-crystallin family K19244 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 421.0
HKD1_k127_7495103_1 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 360.0
HKD1_k127_7495103_2 Protein conserved in bacteria - - - 0.00000000000000000003022 92.0
HKD1_k127_7495956_0 Membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 325.0
HKD1_k127_7495956_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 331.0
HKD1_k127_7495956_2 COG0668 Small-conductance mechanosensitive channel K03442 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022607,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055082,GO:0055085,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000000000000000004225 247.0
HKD1_k127_7495956_3 amino acid - - - 0.0000000000000000008747 85.0
HKD1_k127_7506680_0 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008116 293.0
HKD1_k127_7506680_1 Copper chaperone PCu(A)C K03619,K07152,K09796 GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - 0.00000000000000000000000000000000000000000006741 168.0
HKD1_k127_7506680_2 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.0000000000000000000000000000000000000001737 162.0
HKD1_k127_7509391_0 sptr a7nhu5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 421.0
HKD1_k127_7509391_1 Transposase K07491 - - 0.000000000000000000000000002125 115.0
HKD1_k127_7509391_2 PFAM Transposase DDE domain - - - 0.00000000000000002255 88.0
HKD1_k127_7509391_3 Transposase, IS605 OrfB family K07496 - - 0.000000000001824 73.0
HKD1_k127_7518809_0 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002781 279.0
HKD1_k127_7518809_1 Belongs to the 'phage' integrase family - - - 0.00002358 49.0
HKD1_k127_7529900_0 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000000000000000000003183 158.0
HKD1_k127_7529900_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000001438 123.0
HKD1_k127_7529900_2 - - - - 0.0000000000000000000000000008647 121.0
HKD1_k127_7529900_3 cheY-homologous receiver domain - - - 0.0000000000000000004482 98.0
HKD1_k127_7532065_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 506.0
HKD1_k127_7532065_1 - - - - 0.0000004534 57.0
HKD1_k127_7555122_0 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.0 1177.0
HKD1_k127_7555122_1 Dehydrogenase E1 component K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.0 1043.0
HKD1_k127_7555122_10 Polysulphide reductase, NrfD K00185 - - 6.692e-194 615.0
HKD1_k127_7555122_11 PFAM 4Fe-4S K00184,K21308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 594.0
HKD1_k127_7555122_12 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 524.0
HKD1_k127_7555122_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 497.0
HKD1_k127_7555122_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 469.0
HKD1_k127_7555122_15 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 424.0
HKD1_k127_7555122_16 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 402.0
HKD1_k127_7555122_17 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 403.0
HKD1_k127_7555122_18 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 385.0
HKD1_k127_7555122_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 369.0
HKD1_k127_7555122_2 Glucodextranase, domain N K01178 - 3.2.1.3 0.0 1028.0
HKD1_k127_7555122_20 PFAM Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 340.0
HKD1_k127_7555122_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 310.0
HKD1_k127_7555122_22 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 301.0
HKD1_k127_7555122_23 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001721 276.0
HKD1_k127_7555122_24 Oxidoreductase NAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004674 269.0
HKD1_k127_7555122_25 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000129 255.0
HKD1_k127_7555122_26 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001383 238.0
HKD1_k127_7555122_27 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000006332 239.0
HKD1_k127_7555122_28 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000009074 234.0
HKD1_k127_7555122_29 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001846 235.0
HKD1_k127_7555122_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 1.008e-304 942.0
HKD1_k127_7555122_30 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000002485 231.0
HKD1_k127_7555122_31 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000002697 224.0
HKD1_k127_7555122_32 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000002938 236.0
HKD1_k127_7555122_33 Belongs to the complex I subunit 6 family K00339 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000008253 194.0
HKD1_k127_7555122_34 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000002277 186.0
HKD1_k127_7555122_35 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000002477 171.0
HKD1_k127_7555122_36 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000003608 149.0
HKD1_k127_7555122_37 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000001035 123.0
HKD1_k127_7555122_38 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000000005315 96.0
HKD1_k127_7555122_39 - - - - 0.000000000000000003598 89.0
HKD1_k127_7555122_4 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.659e-277 863.0
HKD1_k127_7555122_40 CAAX protease self-immunity - - - 0.000007965 58.0
HKD1_k127_7555122_41 Cytochrome C oxidase, cbb3-type, subunit III K00368 - 1.7.2.1 0.00001434 48.0
HKD1_k127_7555122_5 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.875e-253 796.0
HKD1_k127_7555122_6 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 2.238e-215 681.0
HKD1_k127_7555122_7 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 4.939e-212 671.0
HKD1_k127_7555122_8 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 4.489e-207 651.0
HKD1_k127_7555122_9 Proton-conducting membrane transporter K00342 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 5.097e-200 637.0
HKD1_k127_7555756_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 6.939e-205 676.0
HKD1_k127_7555756_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 418.0
HKD1_k127_7555756_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000005876 171.0
HKD1_k127_7555756_3 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000004189 71.0
HKD1_k127_7557608_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1239.0
HKD1_k127_7557608_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1028.0
HKD1_k127_7557608_10 Ppx/GppA phosphatase family K01524 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0040007,GO:0044237,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002319 289.0
HKD1_k127_7557608_11 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001321 255.0
HKD1_k127_7557608_12 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000004125 225.0
HKD1_k127_7557608_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000002271 198.0
HKD1_k127_7557608_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000005748 196.0
HKD1_k127_7557608_15 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000009319 177.0
HKD1_k127_7557608_16 NUDIX domain - - - 0.0000000000000000000000000000000003774 139.0
HKD1_k127_7557608_17 Regulatory protein GntR HTH K05799 - - 0.000000000000000000000000000004484 129.0
HKD1_k127_7557608_18 YacP-like NYN domain K06962 - - 0.00000000000000000000000000004243 128.0
HKD1_k127_7557608_19 Cold shock K03704 - - 0.0000000000000000000001482 101.0
HKD1_k127_7557608_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.367e-208 662.0
HKD1_k127_7557608_20 Bacterial Ig-like domain 2 - - - 0.00000000000000001997 98.0
HKD1_k127_7557608_21 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000006905 92.0
HKD1_k127_7557608_22 thiamine diphosphate biosynthetic process K03154 - - 0.0000000001194 70.0
HKD1_k127_7557608_24 Lamin Tail Domain - - - 0.00000003439 67.0
HKD1_k127_7557608_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 587.0
HKD1_k127_7557608_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 488.0
HKD1_k127_7557608_5 Histidyl-tRNA synthetase K00765,K01892,K02502 - 2.4.2.17,6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 482.0
HKD1_k127_7557608_6 Aminotransferase class-V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 461.0
HKD1_k127_7557608_7 Thiazole biosynthesis protein ThiG K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 406.0
HKD1_k127_7557608_8 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 408.0
HKD1_k127_7557608_9 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 349.0
HKD1_k127_7559226_0 Elongation factor SelB, winged helix K03833 - - 4.691e-248 781.0
HKD1_k127_7559226_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 3.359e-235 736.0
HKD1_k127_7559226_10 Glycosyltransferase like family 2 K00721 GO:0000271,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0030258,GO:0030259,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 426.0
HKD1_k127_7559226_11 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 413.0
HKD1_k127_7559226_12 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 406.0
HKD1_k127_7559226_13 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 410.0
HKD1_k127_7559226_14 Transketolase, central region K11381,K21417 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 396.0
HKD1_k127_7559226_15 TRAP transporter solute receptor, TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 389.0
HKD1_k127_7559226_16 E1 component K21416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 372.0
HKD1_k127_7559226_17 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 364.0
HKD1_k127_7559226_18 Alcohol dehydrogenase GroES-like domain K00001,K00008 - 1.1.1.1,1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 363.0
HKD1_k127_7559226_19 PFAM Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 355.0
HKD1_k127_7559226_2 TRAP transporter, 4TM 12TM fusion protein - - - 3.788e-203 650.0
HKD1_k127_7559226_20 PFAM iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 353.0
HKD1_k127_7559226_21 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 344.0
HKD1_k127_7559226_22 E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 344.0
HKD1_k127_7559226_23 Binding-protein-dependent transport system inner membrane component K02026,K17323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 332.0
HKD1_k127_7559226_24 Evidence 4 Homologs of previously reported genes of K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 314.0
HKD1_k127_7559226_25 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 308.0
HKD1_k127_7559226_26 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 307.0
HKD1_k127_7559226_27 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 307.0
HKD1_k127_7559226_28 acetyl coenzyme A synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 308.0
HKD1_k127_7559226_29 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057,K02564 - 3.1.1.31,3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 294.0
HKD1_k127_7559226_3 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 592.0
HKD1_k127_7559226_30 PFAM extracellular solute-binding protein family 1 K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009728 289.0
HKD1_k127_7559226_31 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004718 277.0
HKD1_k127_7559226_32 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002118 273.0
HKD1_k127_7559226_33 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000003916 276.0
HKD1_k127_7559226_34 Mmge prpd family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008594 271.0
HKD1_k127_7559226_35 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002016 269.0
HKD1_k127_7559226_36 Amino acid amide ABC transporter ATP-binding protein 2, HAAT family K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001071 256.0
HKD1_k127_7559226_37 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000191 263.0
HKD1_k127_7559226_38 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000001013 253.0
HKD1_k127_7559226_39 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000003536 230.0
HKD1_k127_7559226_4 Belongs to the GARS family K01945,K01952,K13713 - 6.3.2.6,6.3.4.13,6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 580.0
HKD1_k127_7559226_40 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000001161 225.0
HKD1_k127_7559226_41 - - - - 0.000000000000000000000000000000000000000000000000000000000002234 219.0
HKD1_k127_7559226_42 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000004651 216.0
HKD1_k127_7559226_43 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000008227 209.0
HKD1_k127_7559226_44 PFAM ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000005694 200.0
HKD1_k127_7559226_45 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000207 196.0
HKD1_k127_7559226_46 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000002147 199.0
HKD1_k127_7559226_47 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000002167 198.0
HKD1_k127_7559226_48 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000004137 186.0
HKD1_k127_7559226_49 mRNA catabolic process K06950,K09163 - - 0.00000000000000000000000000000000000000000000000002209 185.0
HKD1_k127_7559226_5 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 561.0
HKD1_k127_7559226_50 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000007938 175.0
HKD1_k127_7559226_51 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000002858 164.0
HKD1_k127_7559226_52 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000001316 169.0
HKD1_k127_7559226_53 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000002247 164.0
HKD1_k127_7559226_54 - - - - 0.0000000000000000000000000000000000000000002273 161.0
HKD1_k127_7559226_55 PFAM conserved - - - 0.000000000000000000000000000000000000000001043 172.0
HKD1_k127_7559226_56 beta-fructofuranosidase activity - - - 0.000000000000000000000000000000000000003248 159.0
HKD1_k127_7559226_57 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000000006081 129.0
HKD1_k127_7559226_58 Molybdopterin converting factor, small subunit K03636 - - 0.00000000000000000000000000002161 120.0
HKD1_k127_7559226_59 Cytidylate kinase-like family - - - 0.00000000000000000000000000009496 128.0
HKD1_k127_7559226_6 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 487.0
HKD1_k127_7559226_60 Cupin 2, conserved barrel domain protein K11312 - - 0.000000000000000000000000002273 115.0
HKD1_k127_7559226_62 Phosphoesterase, PA-phosphatase related K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000000000000000001591 116.0
HKD1_k127_7559226_63 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000002477 110.0
HKD1_k127_7559226_64 PFAM Tripartite ATP-independent periplasmic K11689 - - 0.00000000000000000000001749 106.0
HKD1_k127_7559226_65 DUF35 OB-fold domain, acyl-CoA-associated K07549 - - 0.000000000000000000001445 101.0
HKD1_k127_7559226_66 protein secretion K03116 - - 0.000000000000000002428 85.0
HKD1_k127_7559226_67 Cytochrome C' - - - 0.0000000000000008222 84.0
HKD1_k127_7559226_68 PilZ domain K02676 - - 0.000000000005337 72.0
HKD1_k127_7559226_69 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000001033 75.0
HKD1_k127_7559226_7 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 458.0
HKD1_k127_7559226_70 phosphorelay signal transduction system - - - 0.0000002051 59.0
HKD1_k127_7559226_71 Protein of unknown function (DUF2846) - - - 0.000002413 56.0
HKD1_k127_7559226_72 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00003851 51.0
HKD1_k127_7559226_73 Protein of unknown function (DUF664) - - - 0.0001409 46.0
HKD1_k127_7559226_74 Trap-type c4-dicarboxylate transport system, small permease component K11689,K21394 - - 0.0003695 46.0
HKD1_k127_7559226_8 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 443.0
HKD1_k127_7559226_9 ThiF family K03148,K03636,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 430.0
HKD1_k127_7563708_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 434.0
HKD1_k127_7563708_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 334.0
HKD1_k127_7563708_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 297.0
HKD1_k127_7563708_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 291.0
HKD1_k127_7563708_4 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000002711 223.0
HKD1_k127_7563708_5 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000006785 181.0
HKD1_k127_7563708_6 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000201 166.0
HKD1_k127_7563708_7 ABC transporter substrate binding protein K01989 - - 0.00000000000000005929 81.0
HKD1_k127_7563708_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000001293 75.0
HKD1_k127_7563708_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000004857 57.0
HKD1_k127_7577663_0 recombinase activity - - - 1.473e-259 816.0
HKD1_k127_7577663_1 DNA replication protein - - - 0.00000000001096 68.0
HKD1_k127_7584265_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 396.0
HKD1_k127_7584265_1 Integrase core domain - - - 0.00000000000000000000000004901 114.0
HKD1_k127_7609947_0 HTH-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 377.0
HKD1_k127_7609947_1 - - - - 0.0000000000000000003503 91.0
HKD1_k127_7609947_2 - - - - 0.000004204 52.0
HKD1_k127_7611569_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 313.0
HKD1_k127_7612168_0 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 594.0
HKD1_k127_7612168_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 320.0
HKD1_k127_7615153_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 2.081e-255 796.0
HKD1_k127_7615153_1 carboxylase, biotin carboxylase K01961,K01965,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 465.0
HKD1_k127_7615153_2 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 403.0
HKD1_k127_7615153_3 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000262 270.0
HKD1_k127_7615153_4 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000003887 118.0
HKD1_k127_7615153_5 Biotin-requiring enzyme - - - 0.0009538 45.0
HKD1_k127_7620674_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1022.0
HKD1_k127_7620674_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 456.0
HKD1_k127_7620674_10 4 iron, 4 sulfur cluster binding K00176,K05524 - 1.2.7.3 0.000000000000006868 78.0
HKD1_k127_7620674_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 387.0
HKD1_k127_7620674_3 ATP-grasp domain K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 382.0
HKD1_k127_7620674_4 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 362.0
HKD1_k127_7620674_5 CoA-ligase K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 338.0
HKD1_k127_7620674_6 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 323.0
HKD1_k127_7620674_7 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000006765 202.0
HKD1_k127_7620674_8 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000004774 178.0
HKD1_k127_7620674_9 PFAM Pyruvate K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000007523 166.0
HKD1_k127_7667857_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 378.0
HKD1_k127_7667857_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000002999 130.0
HKD1_k127_7667857_2 SPFH Band 7 PHB domain protein - - - 0.0000000007791 61.0
HKD1_k127_7678489_0 PFAM ABC transporter related K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000987 511.0
HKD1_k127_7678489_1 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 445.0
HKD1_k127_7678489_10 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000000000000000000000000000009745 185.0
HKD1_k127_7678489_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000002891 180.0
HKD1_k127_7678489_12 HIT domain K02503 - - 0.00000000000000000000000000000144 126.0
HKD1_k127_7678489_13 - - - - 0.00000000000000000000000000000214 125.0
HKD1_k127_7678489_14 Nucleoside 2-deoxyribosyltransferase like K08728 - 2.4.2.6 0.00000000000000003174 87.0
HKD1_k127_7678489_15 - - - - 0.000000000005629 73.0
HKD1_k127_7678489_16 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000001394 66.0
HKD1_k127_7678489_17 Thioredoxin-like - - - 0.0000000007311 63.0
HKD1_k127_7678489_18 Thioredoxin-like - - - 0.000000006327 59.0
HKD1_k127_7678489_19 COG1225 Peroxiredoxin - - - 0.00004955 49.0
HKD1_k127_7678489_2 ABC transporter K17215 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 437.0
HKD1_k127_7678489_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 417.0
HKD1_k127_7678489_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 349.0
HKD1_k127_7678489_5 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 317.0
HKD1_k127_7678489_6 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 302.0
HKD1_k127_7678489_7 QueT transporter K16928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005699 280.0
HKD1_k127_7678489_8 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000000000000000000000000000000005112 237.0
HKD1_k127_7678489_9 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000001498 232.0
HKD1_k127_7678663_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 529.0
HKD1_k127_7678663_1 Belongs to the proline racemase family K01777 - 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 426.0
HKD1_k127_7678663_10 Divergent AAA domain K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000003834 235.0
HKD1_k127_7678663_11 Oxidoreductase family, C-terminal alpha beta domain K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000005311 211.0
HKD1_k127_7678663_12 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000224 183.0
HKD1_k127_7678663_13 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000002278 185.0
HKD1_k127_7678663_14 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000008102 177.0
HKD1_k127_7678663_15 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000004388 135.0
HKD1_k127_7678663_16 C2H2-type zinc finger K07376 - 2.7.11.12 0.00009637 49.0
HKD1_k127_7678663_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 343.0
HKD1_k127_7678663_3 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 341.0
HKD1_k127_7678663_4 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 300.0
HKD1_k127_7678663_5 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 294.0
HKD1_k127_7678663_6 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000008061 267.0
HKD1_k127_7678663_7 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000005438 248.0
HKD1_k127_7678663_8 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000005536 238.0
HKD1_k127_7678663_9 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000001662 232.0
HKD1_k127_7700831_0 Arginase family K01479 - 3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 287.0
HKD1_k127_7700831_1 Hydrophobic amino acid ABC transporter (HAAT) family, permease protein K01997 - - 0.00000000000000000000000000000000000000000000000000000000000006025 223.0
HKD1_k127_7700831_2 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000005605 93.0
HKD1_k127_7712346_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 9.76e-242 751.0
HKD1_k127_7712346_1 PFAM isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 2.683e-228 713.0
HKD1_k127_7716914_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 565.0
HKD1_k127_7716914_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 387.0
HKD1_k127_7716914_2 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 348.0
HKD1_k127_7716914_3 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 316.0
HKD1_k127_7716914_4 ATPases associated with a variety of cellular activities K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 304.0
HKD1_k127_7716914_5 - K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 302.0
HKD1_k127_7716914_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000001366 186.0
HKD1_k127_7716914_7 PFAM Polysaccharide deacetylase - - - 0.0000000001346 70.0
HKD1_k127_7721767_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 314.0
HKD1_k127_7721767_1 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000001089 194.0
HKD1_k127_7721767_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000001358 142.0
HKD1_k127_7721767_3 nuclease activity K06218 - - 0.000000000000000247 85.0
HKD1_k127_7744086_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 571.0
HKD1_k127_7744086_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 387.0
HKD1_k127_7744086_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000143 120.0
HKD1_k127_7766797_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 480.0
HKD1_k127_7766797_1 Integrase core domain - - - 0.0000000000000000000000000000000000007547 143.0
HKD1_k127_7783945_0 Bacterial extracellular solute-binding protein K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 588.0
HKD1_k127_7783945_1 PFAM binding-protein-dependent transport systems inner membrane component K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 439.0
HKD1_k127_7783945_2 transmembrane transport K02025,K05814,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 385.0
HKD1_k127_7783945_3 SNARE associated Golgi protein K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000001263 194.0
HKD1_k127_7783945_4 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000001725 173.0
HKD1_k127_7783945_5 OmpA family K03640 - - 0.00000000000000000000000000000000000000009414 159.0
HKD1_k127_7823775_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 536.0
HKD1_k127_7823775_1 transcription factor binding K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 530.0
HKD1_k127_7823775_10 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000002102 248.0
HKD1_k127_7823775_11 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000008711 239.0
HKD1_k127_7823775_12 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01995,K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000001659 236.0
HKD1_k127_7823775_13 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000169 207.0
HKD1_k127_7823775_14 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000002217 189.0
HKD1_k127_7823775_15 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000001668 164.0
HKD1_k127_7823775_16 Cytochrome c - - - 0.0000000000000000002224 93.0
HKD1_k127_7823775_17 Major facilitator Superfamily K08168 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000007453 89.0
HKD1_k127_7823775_19 - - - - 0.00000007717 57.0
HKD1_k127_7823775_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 448.0
HKD1_k127_7823775_21 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 - - 0.000801 49.0
HKD1_k127_7823775_3 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 371.0
HKD1_k127_7823775_4 transport system permease K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 352.0
HKD1_k127_7823775_5 1-aminocyclopropane-1-carboxylate deaminase K01505,K05396 - 3.5.99.7,4.4.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 327.0
HKD1_k127_7823775_6 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 324.0
HKD1_k127_7823775_7 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 304.0
HKD1_k127_7823775_8 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 295.0
HKD1_k127_7823775_9 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003132 262.0
HKD1_k127_7868807_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 458.0
HKD1_k127_7868807_1 transport systems K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 312.0
HKD1_k127_7868807_2 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 307.0
HKD1_k127_7868807_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001634 278.0
HKD1_k127_7868807_4 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000001353 190.0
HKD1_k127_7892180_0 IMG reference gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 359.0
HKD1_k127_7892180_1 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001218 252.0
HKD1_k127_7892180_2 IMG reference gene - - - 0.00000000000000000000000000000000001291 139.0
HKD1_k127_7892180_3 SPTR B2JC10 Transposase IS4 family protein - - - 0.000000000001642 75.0
HKD1_k127_7892180_4 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000003092 62.0
HKD1_k127_7953663_0 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000007595 183.0
HKD1_k127_7999520_0 recombinase activity K03601,K13582 - 3.1.11.6 6.981e-195 631.0
HKD1_k127_8010867_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 467.0
HKD1_k127_8010867_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 378.0
HKD1_k127_8010867_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 366.0
HKD1_k127_8010867_3 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000002861 143.0
HKD1_k127_801772_0 - - - - 0.0000000000000000000000000000000000000000000000003153 183.0
HKD1_k127_801772_1 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000001942 107.0
HKD1_k127_801772_2 - - - - 0.0000000000000000005476 95.0
HKD1_k127_801772_3 Polymer-forming cytoskeletal - - - 0.00000000000003985 79.0
HKD1_k127_801772_4 peptidyl-tyrosine sulfation - - - 0.000000003165 68.0
HKD1_k127_801772_5 - - - - 0.0003077 52.0
HKD1_k127_822671_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000001035 143.0
HKD1_k127_822671_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000001721 80.0
HKD1_k127_822671_2 Diguanylate cyclase - - - 0.00000000000004866 77.0
HKD1_k127_822671_3 helix_turn_helix, Lux Regulon - - - 0.00000000000007904 79.0
HKD1_k127_869371_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1696.0
HKD1_k127_869371_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 544.0
HKD1_k127_869371_2 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.0000000000000000000000008172 109.0
HKD1_k127_869371_3 Rhodopirellula transposase DDE domain - - - 0.000000002817 64.0
HKD1_k127_870969_0 oligoendopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 580.0
HKD1_k127_870969_1 TOBE domain K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 464.0
HKD1_k127_870969_10 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000009273 180.0
HKD1_k127_870969_11 bleomycin resistance protein - - - 0.000000000000000000000000000000000000001799 151.0
HKD1_k127_870969_12 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000000000001134 139.0
HKD1_k127_870969_13 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000004805 117.0
HKD1_k127_870969_14 Protein of unknown function (DUF1571) - - - 0.00000000000000000000005907 106.0
HKD1_k127_870969_15 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000001796 104.0
HKD1_k127_870969_16 Phosphopantetheine attachment site - - - 0.00000002052 66.0
HKD1_k127_870969_17 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 0.0002068 51.0
HKD1_k127_870969_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 443.0
HKD1_k127_870969_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 386.0
HKD1_k127_870969_4 Squalene/phytoene synthase K00801,K02291,K10208 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 371.0
HKD1_k127_870969_5 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006949 267.0
HKD1_k127_870969_6 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000003844 265.0
HKD1_k127_870969_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005826 253.0
HKD1_k127_870969_8 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000904 243.0
HKD1_k127_870969_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000002111 208.0
HKD1_k127_875950_0 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 556.0
HKD1_k127_875950_1 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 329.0
HKD1_k127_875950_2 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002113 249.0
HKD1_k127_875950_3 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000003672 138.0
HKD1_k127_886467_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 375.0
HKD1_k127_886467_1 ATPase (AAA superfamily - - - 0.0000000001528 64.0
HKD1_k127_886685_0 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 407.0
HKD1_k127_886685_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 288.0
HKD1_k127_886685_2 Cysteine rich repeat - - - 0.000000002332 64.0
HKD1_k127_906767_0 FAD dependent oxidoreductase K13796 - - 3.047e-205 649.0
HKD1_k127_906767_1 PFAM Pyridoxal-dependent decarboxylase K01580 - 4.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 599.0
HKD1_k127_906767_2 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 509.0
HKD1_k127_906767_3 Thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 468.0
HKD1_k127_906767_4 TIGRFAM CitB domain protein K13795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 417.0
HKD1_k127_906767_5 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 310.0
HKD1_k127_906767_6 Universal stress protein UspA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 287.0
HKD1_k127_906767_7 of the drug metabolite transporter (DMT) superfamily - GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015318,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000004102 214.0
HKD1_k127_928880_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 389.0
HKD1_k127_928880_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 335.0
HKD1_k127_928880_2 Protein of unknown function (DUF1275) - - - 0.000000000000000000000000000005532 129.0
HKD1_k127_93303_0 PFAM Transposase IS66 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 521.0
HKD1_k127_93303_1 Plasmid pRiA4b ORF-3-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 381.0
HKD1_k127_93303_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000246 221.0
HKD1_k127_93303_3 - - - - 0.000000000000000000000000000000000000000004399 169.0
HKD1_k127_93303_4 PFAM IS66 Orf2 like protein K07484 - - 0.000000000000000000000000000006986 125.0
HKD1_k127_93303_5 - - - - 0.0000000006516 68.0
HKD1_k127_97709_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 3.026e-209 668.0
HKD1_k127_97709_1 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 567.0
HKD1_k127_97709_10 Spermidine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003707 282.0
HKD1_k127_97709_11 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000001865 272.0
HKD1_k127_97709_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000004371 243.0
HKD1_k127_97709_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005583 250.0
HKD1_k127_97709_14 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000002086 254.0
HKD1_k127_97709_15 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000004469 193.0
HKD1_k127_97709_16 chain release factor K15034 - - 0.0000000000000000000000000000000000000001475 154.0
HKD1_k127_97709_17 SMART Water Stress and Hypersensitive response - - - 0.0000000000000000000000000000002379 130.0
HKD1_k127_97709_2 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 450.0
HKD1_k127_97709_3 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 432.0
HKD1_k127_97709_4 SIS domain K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 402.0
HKD1_k127_97709_5 mevalonate kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 383.0
HKD1_k127_97709_6 Protein of unknown function (DUF1116) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 368.0
HKD1_k127_97709_7 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 331.0
HKD1_k127_97709_8 MobA-like NTP transferase domain K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 326.0
HKD1_k127_97709_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 304.0
HKD1_k127_995451_0 MgtE intracellular - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 388.0
HKD1_k127_995451_1 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000001756 171.0