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Overview

ID MAG01738
Name HKD1_bin.55
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Verrucomicrobiota
Class Verrucomicrobiia
Order Chthoniobacterales
Family UBA10450
Genus Udaeobacter
Species
Assembly information
Completeness (%) 93.08
Contamination (%) 0.79
GC content (%) 55.0
N50 (bp) 22,664
Genome size (bp) 2,619,457

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2289

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1014383_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 408.0
HKD1_k127_1014383_1 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 344.0
HKD1_k127_1014383_2 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005147 286.0
HKD1_k127_1014383_3 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000001591 214.0
HKD1_k127_1014383_4 response to heat K07090 - - 0.000000000000000000000000000000007785 137.0
HKD1_k127_1014383_5 Cation transport ATPase K17686 - 3.6.3.54 0.00000057 53.0
HKD1_k127_1014383_6 - - - - 0.000000725 55.0
HKD1_k127_1014383_7 - - - - 0.000002182 57.0
HKD1_k127_10189_0 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 309.0
HKD1_k127_10189_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000001766 133.0
HKD1_k127_10189_2 Oxidoreductase FAD-binding domain protein - - - 0.000000000000000000001374 106.0
HKD1_k127_10189_3 general secretion pathway protein K02456,K02679 - - 0.00003753 54.0
HKD1_k127_1053652_0 Cytochrome C oxidase subunit I K02274 - 1.9.3.1 8.093e-206 654.0
HKD1_k127_1053652_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 486.0
HKD1_k127_1053652_10 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000002568 146.0
HKD1_k127_1053652_11 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000008806 138.0
HKD1_k127_1053652_12 AMP binding - - - 0.0000000000000000000000006036 112.0
HKD1_k127_1053652_13 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000001014 89.0
HKD1_k127_1053652_14 Trypsin-like peptidase domain - - - 0.00000000000000001188 95.0
HKD1_k127_1053652_15 signal sequence binding K07152 - - 0.00000000000000004143 90.0
HKD1_k127_1053652_16 Cytochrome c K02275,K17223 - 1.9.3.1 0.000000000000001515 87.0
HKD1_k127_1053652_17 Cytochrome c - - - 0.00000008052 64.0
HKD1_k127_1053652_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 479.0
HKD1_k127_1053652_3 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 361.0
HKD1_k127_1053652_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 315.0
HKD1_k127_1053652_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 301.0
HKD1_k127_1053652_6 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 289.0
HKD1_k127_1053652_7 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001437 265.0
HKD1_k127_1053652_8 Cytochrome c K02305 - - 0.0000000000000000000000000000000000000000000000000000000000105 224.0
HKD1_k127_1053652_9 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000000000000007959 179.0
HKD1_k127_1054411_0 DNA recombination protein RmuC K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 389.0
HKD1_k127_1054411_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008712,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901576,GO:1903509 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 346.0
HKD1_k127_1054411_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 339.0
HKD1_k127_1054411_3 TonB dependent receptor K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 334.0
HKD1_k127_1054411_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001424 265.0
HKD1_k127_1054411_5 metallo-beta-lactamase - - - 0.0000000000000000000000000000001963 124.0
HKD1_k127_1061579_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 306.0
HKD1_k127_1061579_1 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000000000000000000000000001939 148.0
HKD1_k127_1061579_2 - - - - 0.000000000000000000000000000000009114 128.0
HKD1_k127_1061579_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000005509 119.0
HKD1_k127_1061579_4 Belongs to the universal stress protein A family - - - 0.0000000000000000000000008869 113.0
HKD1_k127_1061579_5 Protein required for attachment to host cells - - - 0.000008166 53.0
HKD1_k127_1085077_0 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 619.0
HKD1_k127_1085077_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 548.0
HKD1_k127_1085077_10 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.000000000000000000000000000000000000000000000000004199 184.0
HKD1_k127_1085077_11 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000004098 175.0
HKD1_k127_1085077_12 PIN domain - - - 0.000000000000000000000000000000000009293 141.0
HKD1_k127_1085077_13 - - - - 0.0000000000000000000000000000000000762 140.0
HKD1_k127_1085077_14 cAMP biosynthetic process - - - 0.00000000000000000002961 101.0
HKD1_k127_1085077_15 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.00000001018 59.0
HKD1_k127_1085077_16 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000005633 53.0
HKD1_k127_1085077_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 431.0
HKD1_k127_1085077_3 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 435.0
HKD1_k127_1085077_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 432.0
HKD1_k127_1085077_5 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 399.0
HKD1_k127_1085077_6 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 394.0
HKD1_k127_1085077_7 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 364.0
HKD1_k127_1085077_8 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 349.0
HKD1_k127_1085077_9 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000002193 260.0
HKD1_k127_1091135_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 454.0
HKD1_k127_1091135_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 405.0
HKD1_k127_1091135_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 310.0
HKD1_k127_1091135_3 DNA-templated transcription, initiation - - - 0.0000000000000006435 80.0
HKD1_k127_1096930_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1035.0
HKD1_k127_1096930_1 Flavin containing amine oxidoreductase - - - 1.195e-226 711.0
HKD1_k127_1096930_2 PFAM deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 523.0
HKD1_k127_1096930_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 520.0
HKD1_k127_1096930_4 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 426.0
HKD1_k127_1096930_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 311.0
HKD1_k127_1096930_6 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000193 272.0
HKD1_k127_1156630_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.74e-201 634.0
HKD1_k127_1156630_1 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 561.0
HKD1_k127_1156630_10 Major Facilitator Superfamily - - - 0.000000001164 63.0
HKD1_k127_1156630_12 Protein of unknown function (DUF1360) - - - 0.000001062 55.0
HKD1_k127_1156630_2 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002069 258.0
HKD1_k127_1156630_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000001941 225.0
HKD1_k127_1156630_4 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000622 220.0
HKD1_k127_1156630_5 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000007951 214.0
HKD1_k127_1156630_6 inorganic diphosphatase activity K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000002668 195.0
HKD1_k127_1156630_7 Histidine kinase - - - 0.000000000000000000000000000000000000003365 161.0
HKD1_k127_1156630_8 Low affinity iron permease - - - 0.00000000000000000000000000000000004435 142.0
HKD1_k127_1156630_9 aminopeptidase activity K01266 - 3.4.11.19 0.0000000000000000000001665 99.0
HKD1_k127_1168544_0 glycosyl transferase family 2 - - - 2.742e-216 683.0
HKD1_k127_1168544_1 SMART metal-dependent phosphohydrolase HD region K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 473.0
HKD1_k127_1168544_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 315.0
HKD1_k127_1168544_11 Flavoprotein K01598 - 4.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000003771 252.0
HKD1_k127_1168544_12 Guanylate kinase K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000001437 247.0
HKD1_k127_1168544_13 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000002144 194.0
HKD1_k127_1168544_14 - - - - 0.00000000000000000000000000000000000000001758 161.0
HKD1_k127_1168544_15 Type I 3-dehydroquinase K03785 - 4.2.1.10 0.000000000000000000000000000000000000002446 154.0
HKD1_k127_1168544_16 Belongs to the bacterial histone-like protein family K03530,K04764 - - 0.000000000000000000000000000000000000003095 150.0
HKD1_k127_1168544_17 PFAM peptidase S16 lon domain protein K01338 - 3.4.21.53 0.000000000000000000000000000000000000325 150.0
HKD1_k127_1168544_18 e3 binding domain - - - 0.000000000000000000005388 96.0
HKD1_k127_1168544_19 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000006016 86.0
HKD1_k127_1168544_2 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 404.0
HKD1_k127_1168544_20 Protein of unknown function (DUF1232) - - - 0.00000000002168 71.0
HKD1_k127_1168544_21 Binds directly to 16S ribosomal RNA K02968 - - 0.000002722 53.0
HKD1_k127_1168544_3 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 399.0
HKD1_k127_1168544_4 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 384.0
HKD1_k127_1168544_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03471 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 374.0
HKD1_k127_1168544_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 350.0
HKD1_k127_1168544_7 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 355.0
HKD1_k127_1168544_8 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 339.0
HKD1_k127_1168544_9 endonuclease III K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 330.0
HKD1_k127_1198903_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 403.0
HKD1_k127_1198903_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 336.0
HKD1_k127_1198903_2 PFAM Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001522 278.0
HKD1_k127_1198903_3 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000004741 230.0
HKD1_k127_1198903_4 Protein of unknown function (DUF721) - - - 0.00000000000000000000000000000001471 133.0
HKD1_k127_1198903_5 rieske 2fe-2s - - - 0.0000000000000000000001108 103.0
HKD1_k127_1198903_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000003621 69.0
HKD1_k127_1198903_7 Animal haem peroxidase - - - 0.00000000000138 74.0
HKD1_k127_1198903_8 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K20202 - 1.8.1.19 0.000000000005706 67.0
HKD1_k127_1204864_0 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 449.0
HKD1_k127_1204864_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 432.0
HKD1_k127_1204864_2 Conserved repeat domain - - - 0.000000000000000000000000005886 117.0
HKD1_k127_1204864_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.0000000000002489 71.0
HKD1_k127_1204864_4 PHP domain protein K07053 - 3.1.3.97 0.00003477 54.0
HKD1_k127_1216074_0 Belongs to the succinate malate CoA ligase beta subunit family K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 405.0
HKD1_k127_1216074_1 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 385.0
HKD1_k127_1216074_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 366.0
HKD1_k127_1216074_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 328.0
HKD1_k127_1216074_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000009856 265.0
HKD1_k127_1216074_5 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.0000000000000000000000000000000000006909 156.0
HKD1_k127_1216074_6 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000001994 54.0
HKD1_k127_1256733_0 DNA topoisomerase III K03169 - 5.99.1.2 7.442e-288 912.0
HKD1_k127_1256733_1 MacB-like periplasmic core domain - - - 1.353e-283 894.0
HKD1_k127_1256733_10 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 417.0
HKD1_k127_1256733_11 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 333.0
HKD1_k127_1256733_12 helix_turn_helix, Lux Regulon K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008636 269.0
HKD1_k127_1256733_13 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004513 263.0
HKD1_k127_1256733_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004034 261.0
HKD1_k127_1256733_15 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004921 265.0
HKD1_k127_1256733_16 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007872 247.0
HKD1_k127_1256733_17 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002231 244.0
HKD1_k127_1256733_18 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003154 243.0
HKD1_k127_1256733_19 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000005577 223.0
HKD1_k127_1256733_2 aminopeptidase N K01256 - 3.4.11.2 3.964e-272 864.0
HKD1_k127_1256733_20 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000206 194.0
HKD1_k127_1256733_21 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000002262 193.0
HKD1_k127_1256733_22 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000001178 186.0
HKD1_k127_1256733_23 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000002531 180.0
HKD1_k127_1256733_24 Domain of unknown function (DUF5069) - - - 0.000000000000000000000000000000000000000000000003299 177.0
HKD1_k127_1256733_25 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000399 172.0
HKD1_k127_1256733_26 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.0000000000000000000000000000000000000001076 155.0
HKD1_k127_1256733_28 - - - - 0.000000000000000000000000000002458 123.0
HKD1_k127_1256733_29 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000668 121.0
HKD1_k127_1256733_3 ABC transporter - - - 1.15e-214 683.0
HKD1_k127_1256733_30 EamA-like transporter family - - - 0.000000000000000000000000006336 123.0
HKD1_k127_1256733_31 - - - - 0.000000000000000000001014 100.0
HKD1_k127_1256733_32 PAS fold K02491 - 2.7.13.3 0.00000000000000000005193 106.0
HKD1_k127_1256733_33 - - - - 0.0000000000000000001167 92.0
HKD1_k127_1256733_34 Ribosomal protein L34 K02914 - - 0.0000000000000000001204 90.0
HKD1_k127_1256733_35 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000002553 92.0
HKD1_k127_1256733_36 - - - - 0.00000000000000006106 84.0
HKD1_k127_1256733_37 Ribosomal protein L35 K02916 - - 0.0000000000000906 76.0
HKD1_k127_1256733_4 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 1.632e-200 632.0
HKD1_k127_1256733_40 Sulfatase-modifying factor enzyme 1 - - - 0.000001301 50.0
HKD1_k127_1256733_41 Sulfatase-modifying factor enzyme 1 - - - 0.000002832 49.0
HKD1_k127_1256733_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 501.0
HKD1_k127_1256733_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 498.0
HKD1_k127_1256733_7 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 467.0
HKD1_k127_1256733_8 unsaturated fatty acid biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 435.0
HKD1_k127_1256733_9 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 411.0
HKD1_k127_1320957_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.384e-296 922.0
HKD1_k127_1320957_1 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 423.0
HKD1_k127_1320957_10 - - - - 0.0000000001415 69.0
HKD1_k127_1320957_2 Chlorite dismutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 342.0
HKD1_k127_1320957_3 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 299.0
HKD1_k127_1320957_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000005868 157.0
HKD1_k127_1320957_5 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000003705 131.0
HKD1_k127_1320957_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000002762 96.0
HKD1_k127_1320957_7 chlorophyll binding - - - 0.0000000000000000000029 99.0
HKD1_k127_1320957_8 - - - - 0.00000000000000002187 93.0
HKD1_k127_1320957_9 O-methyltransferase activity - - - 0.0000000000000002587 88.0
HKD1_k127_1343469_0 RecF/RecN/SMC N terminal domain K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 566.0
HKD1_k127_1343469_1 Fumarylacetoacetase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 508.0
HKD1_k127_1343469_10 - - - - 0.000000000000000000001336 100.0
HKD1_k127_1343469_11 - - - - 0.0003797 46.0
HKD1_k127_1343469_2 Pyridine nucleotide-disulphide oxidoreductase K00362,K07001 - 1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 451.0
HKD1_k127_1343469_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 365.0
HKD1_k127_1343469_4 PFAM Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 306.0
HKD1_k127_1343469_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 287.0
HKD1_k127_1343469_6 PFAM GPR1 FUN34 yaaH family protein K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001869 271.0
HKD1_k127_1343469_7 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000001563 230.0
HKD1_k127_1343469_8 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000001377 172.0
HKD1_k127_1343469_9 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000006196 166.0
HKD1_k127_134799_0 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 556.0
HKD1_k127_134799_1 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 479.0
HKD1_k127_134799_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000001872 62.0
HKD1_k127_1350150_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1190.0
HKD1_k127_1350150_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 9.14e-264 842.0
HKD1_k127_1350150_10 Belongs to the universal stress protein A family - - - 0.000000000000000001235 94.0
HKD1_k127_1350150_11 CoA binding domain K09181 - - 0.0000000001154 64.0
HKD1_k127_1350150_12 NlpC/P60 family - - - 0.0000000002496 72.0
HKD1_k127_1350150_2 FtsX-like permease family K02004 - - 2.556e-235 752.0
HKD1_k127_1350150_3 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 554.0
HKD1_k127_1350150_4 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 359.0
HKD1_k127_1350150_5 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 359.0
HKD1_k127_1350150_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 344.0
HKD1_k127_1350150_7 - - - - 0.000000000000000000000000000000000000001634 151.0
HKD1_k127_1350150_8 Haem-binding domain - - - 0.000000000000000000000000000000000000002372 151.0
HKD1_k127_1350150_9 Universal stress protein family - - - 0.000000000000000000000000000000000000004364 157.0
HKD1_k127_1360977_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 2.432e-283 886.0
HKD1_k127_1360977_1 peptidase activity K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 597.0
HKD1_k127_1360977_2 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 342.0
HKD1_k127_1407082_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.258e-306 955.0
HKD1_k127_1407082_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.341e-276 864.0
HKD1_k127_1407082_10 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 439.0
HKD1_k127_1407082_11 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 422.0
HKD1_k127_1407082_12 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 412.0
HKD1_k127_1407082_13 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 402.0
HKD1_k127_1407082_14 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 389.0
HKD1_k127_1407082_15 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 366.0
HKD1_k127_1407082_16 Proteasome subunit K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 359.0
HKD1_k127_1407082_17 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 364.0
HKD1_k127_1407082_18 Proteasome subunit K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 308.0
HKD1_k127_1407082_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 307.0
HKD1_k127_1407082_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 3.59e-255 801.0
HKD1_k127_1407082_20 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.000000000000000000000000000000000000000000000000000000000000000000000000000000181 278.0
HKD1_k127_1407082_21 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000003504 248.0
HKD1_k127_1407082_22 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000006143 240.0
HKD1_k127_1407082_23 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000169 230.0
HKD1_k127_1407082_24 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000006318 227.0
HKD1_k127_1407082_25 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000001404 215.0
HKD1_k127_1407082_26 nUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000001761 207.0
HKD1_k127_1407082_27 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000000000000000000000000001671 198.0
HKD1_k127_1407082_28 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000002709 184.0
HKD1_k127_1407082_29 Ami_3 - - - 0.00000000000000000000000000000000000000000000004835 179.0
HKD1_k127_1407082_3 ABC transporter transmembrane region K06147 - - 1.281e-242 765.0
HKD1_k127_1407082_30 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000009925 173.0
HKD1_k127_1407082_31 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000001002 175.0
HKD1_k127_1407082_32 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000000000000000000000000001718 176.0
HKD1_k127_1407082_33 - - - - 0.0000000000000000000000000000000000000000008463 162.0
HKD1_k127_1407082_34 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.0000000000000000000000000000000001647 138.0
HKD1_k127_1407082_35 ACT domain - - - 0.000000000000000000000000000000004329 134.0
HKD1_k127_1407082_36 - - - - 0.00000000000000000000000000000002975 131.0
HKD1_k127_1407082_37 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000008415 122.0
HKD1_k127_1407082_38 May function as a protein modifier covalently attached to lysine residues of substrate proteins. This may serve to target the modified proteins for degradation by proteasomes - - - 0.0000000000000000000000001401 107.0
HKD1_k127_1407082_39 Belongs to the UPF0761 family K07058 - - 0.0000000000000000000000003597 116.0
HKD1_k127_1407082_4 Outer membrane protein assembly complex, YaeT protein K07277 - - 9.863e-195 632.0
HKD1_k127_1407082_40 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000004287 107.0
HKD1_k127_1407082_42 Aspartyl protease - - - 0.0000000001294 74.0
HKD1_k127_1407082_43 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000141 66.0
HKD1_k127_1407082_45 Domain of unknown function (DUF4912) K09942 - - 0.0000001274 62.0
HKD1_k127_1407082_5 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 595.0
HKD1_k127_1407082_6 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 546.0
HKD1_k127_1407082_7 - K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 535.0
HKD1_k127_1407082_8 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 485.0
HKD1_k127_1407082_9 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 462.0
HKD1_k127_1439320_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1334.0
HKD1_k127_1439320_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.318e-234 736.0
HKD1_k127_1439320_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 397.0
HKD1_k127_1439515_0 transporter - - - 8.186e-283 884.0
HKD1_k127_1439515_1 Urocanase Rossmann-like domain K01712 - 4.2.1.49 9.563e-268 833.0
HKD1_k127_1439515_10 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 359.0
HKD1_k127_1439515_11 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 329.0
HKD1_k127_1439515_12 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 307.0
HKD1_k127_1439515_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 291.0
HKD1_k127_1439515_14 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001168 252.0
HKD1_k127_1439515_15 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000329 226.0
HKD1_k127_1439515_16 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000000000000000000003465 215.0
HKD1_k127_1439515_17 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000002847 199.0
HKD1_k127_1439515_18 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000004205 167.0
HKD1_k127_1439515_19 response to oxidative stress - - - 0.000000000000000000000000000000000000001944 151.0
HKD1_k127_1439515_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 3.773e-226 706.0
HKD1_k127_1439515_20 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000004468 137.0
HKD1_k127_1439515_21 - - - - 0.000000000000000000000000000000005962 134.0
HKD1_k127_1439515_23 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000001 63.0
HKD1_k127_1439515_24 hydrolase K01048 - 3.1.1.5 0.000009944 49.0
HKD1_k127_1439515_25 YXWGXW repeat (2 copies) - - - 0.0002075 48.0
HKD1_k127_1439515_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 1.197e-214 673.0
HKD1_k127_1439515_4 Glutamate formimidoyltransferase K00603,K13990 - 2.1.2.5,4.3.1.4 3.22e-207 658.0
HKD1_k127_1439515_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 538.0
HKD1_k127_1439515_6 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 506.0
HKD1_k127_1439515_7 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 494.0
HKD1_k127_1439515_8 Competence-damaged protein K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 430.0
HKD1_k127_1439515_9 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 381.0
HKD1_k127_1457237_0 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 407.0
HKD1_k127_1457237_1 selenide, water dikinase activity K01008,K04487 - 2.7.9.3,2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 302.0
HKD1_k127_1457237_2 Elongation factor SelB, winged helix K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.00000000000000000000000000000000000003944 154.0
HKD1_k127_1457237_3 Rdx family K07401 - - 0.0000000000003868 70.0
HKD1_k127_1472251_0 Predicted membrane protein (DUF2339) - - - 1.556e-249 802.0
HKD1_k127_1472251_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 375.0
HKD1_k127_1472251_10 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006804 247.0
HKD1_k127_1472251_11 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000004418 180.0
HKD1_k127_1472251_12 Small integral membrane protein - - - 0.0000000000000000000000000000000000000009418 153.0
HKD1_k127_1472251_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000005968 123.0
HKD1_k127_1472251_14 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000005813 115.0
HKD1_k127_1472251_16 Protein of unknown function (DUF1059) - - - 0.000000000000000002238 87.0
HKD1_k127_1472251_18 - - - - 0.000000000000005853 82.0
HKD1_k127_1472251_19 Kelch motif - - - 0.00000000000001307 87.0
HKD1_k127_1472251_2 Transglycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 382.0
HKD1_k127_1472251_20 surface antigen - - - 0.00000000001304 76.0
HKD1_k127_1472251_21 PFAM Protein kinase domain - - - 0.000000002171 70.0
HKD1_k127_1472251_22 COG3794 Plastocyanin - - - 0.000000003833 69.0
HKD1_k127_1472251_3 Peptidogalycan biosysnthesis/recognition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 361.0
HKD1_k127_1472251_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 324.0
HKD1_k127_1472251_5 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 298.0
HKD1_k127_1472251_6 Alpha-2-Macroglobulin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 320.0
HKD1_k127_1472251_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002748 283.0
HKD1_k127_1472251_8 Small-conductance mechanosensitive channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002554 257.0
HKD1_k127_1472251_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008238 258.0
HKD1_k127_1515324_0 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 363.0
HKD1_k127_1515324_1 COG1796 DNA polymerase IV (family X) K02347 - - 0.00000000000000000000000000000000000000000000005525 183.0
HKD1_k127_1515324_2 UPF0391 membrane protein - - - 0.000000000000002197 76.0
HKD1_k127_1600897_0 alpha amylase catalytic K01182,K05343 - 3.2.1.1,3.2.1.10,5.4.99.16 2.013e-282 889.0
HKD1_k127_1600897_1 RecG wedge domain K03655 - 3.6.4.12 7.124e-244 781.0
HKD1_k127_1600897_10 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000002424 196.0
HKD1_k127_1600897_11 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000001896 93.0
HKD1_k127_1600897_12 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000004374 66.0
HKD1_k127_1600897_2 DHHA1 domain K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 519.0
HKD1_k127_1600897_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 490.0
HKD1_k127_1600897_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 330.0
HKD1_k127_1600897_5 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 280.0
HKD1_k127_1600897_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002491 284.0
HKD1_k127_1600897_7 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000002131 226.0
HKD1_k127_1600897_8 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000004289 220.0
HKD1_k127_1600897_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000007208 213.0
HKD1_k127_1656899_0 Major facilitator Superfamily K03446,K07786 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 1.211e-264 826.0
HKD1_k127_1656899_1 PFAM secretion protein HlyD family protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 567.0
HKD1_k127_1656899_2 COG0346 Lactoylglutathione lyase and related lyases K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 362.0
HKD1_k127_1656899_3 - - - - 0.0000000000000000000000000000000000000000000003827 172.0
HKD1_k127_16613_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1015.0
HKD1_k127_16613_1 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.939e-287 899.0
HKD1_k127_16613_10 ATPases associated with a variety of cellular activities K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 375.0
HKD1_k127_16613_11 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 316.0
HKD1_k127_16613_12 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 303.0
HKD1_k127_16613_13 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 306.0
HKD1_k127_16613_14 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001131 256.0
HKD1_k127_16613_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002778 255.0
HKD1_k127_16613_16 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000002372 232.0
HKD1_k127_16613_17 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000001677 246.0
HKD1_k127_16613_18 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000007781 227.0
HKD1_k127_16613_19 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000001562 222.0
HKD1_k127_16613_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.811e-222 698.0
HKD1_k127_16613_20 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000009786 210.0
HKD1_k127_16613_21 negative regulation of translational initiation - - - 0.0000000000000000000000000000000000000000000000000000000002937 210.0
HKD1_k127_16613_22 Segregation and condensation complex subunit ScpB - - - 0.000000000000000000000000000000000000000000000000000000005379 206.0
HKD1_k127_16613_23 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000001723 178.0
HKD1_k127_16613_24 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000006473 180.0
HKD1_k127_16613_25 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000003611 159.0
HKD1_k127_16613_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.000000000000000000000000000000000000002971 149.0
HKD1_k127_16613_28 TPM domain - - - 0.0000000000000000000000000000000000003384 147.0
HKD1_k127_16613_29 membrane - - - 0.00000000000000000000000000000038 135.0
HKD1_k127_16613_3 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 600.0
HKD1_k127_16613_30 - - - - 0.0000000000000000000000000008555 128.0
HKD1_k127_16613_31 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000007325 110.0
HKD1_k127_16613_32 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000006175 114.0
HKD1_k127_16613_33 Peptidase family M48 - - - 0.0000000000000000001965 104.0
HKD1_k127_16613_34 Domain of unknown function (DUF4440) - - - 0.00000000007473 69.0
HKD1_k127_16613_35 - - - - 0.000001308 57.0
HKD1_k127_16613_4 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 580.0
HKD1_k127_16613_5 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 506.0
HKD1_k127_16613_6 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 507.0
HKD1_k127_16613_7 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 496.0
HKD1_k127_16613_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 486.0
HKD1_k127_16613_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 479.0
HKD1_k127_16983_0 Peptidase dimerisation domain - - - 2.032e-199 629.0
HKD1_k127_16983_1 DNA polymerase type-B family K02336 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 427.0
HKD1_k127_1729483_0 phosphoesterase, PA-phosphatase related - - - 4.174e-223 706.0
HKD1_k127_1729483_1 Belongs to the aldehyde dehydrogenase family K00128,K10217 - 1.2.1.3,1.2.1.32,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 614.0
HKD1_k127_1729483_2 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 532.0
HKD1_k127_1729483_3 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 474.0
HKD1_k127_1729483_4 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 349.0
HKD1_k127_1729483_5 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000000000003528 216.0
HKD1_k127_1729483_6 Translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.000000000000000000000000000000000000000000000000000000008729 200.0
HKD1_k127_1729483_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000002447 160.0
HKD1_k127_1729483_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000003151 154.0
HKD1_k127_1729483_9 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000005478 132.0
HKD1_k127_183688_0 AcrB/AcrD/AcrF family - - - 0.0 1326.0
HKD1_k127_183688_1 Thi4 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 581.0
HKD1_k127_183688_10 outer membrane efflux protein K03287 - - 0.0000000000003419 82.0
HKD1_k127_183688_2 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 345.0
HKD1_k127_183688_3 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 315.0
HKD1_k127_183688_4 ornithine cyclodeaminase activity K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 308.0
HKD1_k127_183688_5 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004981 265.0
HKD1_k127_183688_6 Alpha-aspartyl dipeptidase-like K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.00000000000000000000000000000000000000000000000000000000000000000000001055 249.0
HKD1_k127_183688_7 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000225 223.0
HKD1_k127_183688_8 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000005722 220.0
HKD1_k127_183688_9 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000007601 145.0
HKD1_k127_2067_0 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 563.0
HKD1_k127_2067_1 Protein of unknown function (DUF3302) - - - 0.0000000000000000000000000000000000000000000000000000003709 197.0
HKD1_k127_2067_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000158 178.0
HKD1_k127_2067_3 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000005149 144.0
HKD1_k127_2099149_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 9.098e-254 803.0
HKD1_k127_2099149_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 366.0
HKD1_k127_2099149_2 PhoU domain K02039 - - 0.0000000000000000000000000000000000000000000000000000000002266 212.0
HKD1_k127_2099149_3 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.0000000000000000000000000000000000000005858 151.0
HKD1_k127_2099149_4 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000202 139.0
HKD1_k127_2100153_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1269.0
HKD1_k127_2100153_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 503.0
HKD1_k127_2100153_10 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009707 271.0
HKD1_k127_2100153_11 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001196 275.0
HKD1_k127_2100153_12 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003694 230.0
HKD1_k127_2100153_13 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000004532 236.0
HKD1_k127_2100153_14 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000002431 214.0
HKD1_k127_2100153_15 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000003494 182.0
HKD1_k127_2100153_16 S1/P1 Nuclease - - - 0.00000000000000000000000000003972 130.0
HKD1_k127_2100153_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 469.0
HKD1_k127_2100153_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 464.0
HKD1_k127_2100153_4 C-terminal domain of 1-Cys peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 391.0
HKD1_k127_2100153_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 405.0
HKD1_k127_2100153_6 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 361.0
HKD1_k127_2100153_7 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 329.0
HKD1_k127_2100153_8 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 323.0
HKD1_k127_2100153_9 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008719 283.0
HKD1_k127_2106691_0 TamB, inner membrane protein subunit of TAM complex - - - 0.0000000000000000000000000000000003243 144.0
HKD1_k127_2106691_1 PFAM purine or other phosphorylase family 1 K01243 - 3.2.2.9 0.00000000003232 72.0
HKD1_k127_211342_0 Selenium-binding protein K17285 - - 4.364e-232 725.0
HKD1_k127_211342_1 Glycosyltransferase family 9 (heptosyltransferase) K02517,K02843 - 2.3.1.241 3.025e-206 661.0
HKD1_k127_211342_2 Methyltransferase type 11 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 460.0
HKD1_k127_211342_3 Glycoside-hydrolase family GH114 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 374.0
HKD1_k127_211342_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 296.0
HKD1_k127_211342_5 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003973 273.0
HKD1_k127_211342_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000008261 266.0
HKD1_k127_211342_7 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002557 261.0
HKD1_k127_211342_8 DNA methylase - - - 0.00000000000000000000000000000000000000000000000000000000000004573 216.0
HKD1_k127_211342_9 - - - - 0.000000000000000000000000000000000000000000000000000000004091 207.0
HKD1_k127_2127862_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 9.455e-227 712.0
HKD1_k127_2127862_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 421.0
HKD1_k127_2127862_10 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000001782 202.0
HKD1_k127_2127862_11 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000003085 194.0
HKD1_k127_2127862_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000003213 188.0
HKD1_k127_2127862_13 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000007362 176.0
HKD1_k127_2127862_14 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000004426 163.0
HKD1_k127_2127862_15 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000001436 157.0
HKD1_k127_2127862_16 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000001754 135.0
HKD1_k127_2127862_17 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000458 127.0
HKD1_k127_2127862_18 - - - - 0.00000000000000000000000000001527 128.0
HKD1_k127_2127862_19 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000001434 114.0
HKD1_k127_2127862_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 391.0
HKD1_k127_2127862_20 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000001901 113.0
HKD1_k127_2127862_21 Ribosomal L29 protein K02904 - - 0.000000000000004721 77.0
HKD1_k127_2127862_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 357.0
HKD1_k127_2127862_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004561 265.0
HKD1_k127_2127862_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004879 253.0
HKD1_k127_2127862_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000583 250.0
HKD1_k127_2127862_7 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009281 248.0
HKD1_k127_2127862_8 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002221 246.0
HKD1_k127_2127862_9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000003724 230.0
HKD1_k127_2157911_0 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 450.0
HKD1_k127_2157911_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 432.0
HKD1_k127_2157911_2 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 348.0
HKD1_k127_2157911_3 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 340.0
HKD1_k127_2157911_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004146 238.0
HKD1_k127_2157911_5 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000003622 239.0
HKD1_k127_2157911_6 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000008373 236.0
HKD1_k127_2166535_0 Glycosyl transferase family 21 - - - 0.0 1127.0
HKD1_k127_2166535_1 arginine decarboxylase K01585 - 4.1.1.19 2.19e-300 932.0
HKD1_k127_2166535_10 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 426.0
HKD1_k127_2166535_11 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 426.0
HKD1_k127_2166535_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 431.0
HKD1_k127_2166535_13 organic acid phosphorylation K00865 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 324.0
HKD1_k127_2166535_14 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001495 226.0
HKD1_k127_2166535_15 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000009918 219.0
HKD1_k127_2166535_16 Necessary for normal cell division and for the maintenance of normal septation - - - 0.0000000000000000000000000000000000000000000000004036 192.0
HKD1_k127_2166535_17 cell redox homeostasis - - - 0.000000000000000000000000000000000000001498 153.0
HKD1_k127_2166535_18 TIGRFAM phosphocarrier, HPr family K11189 - - 0.00000000000000000000000000000000003519 136.0
HKD1_k127_2166535_19 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000001149 149.0
HKD1_k127_2166535_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 7.3e-295 913.0
HKD1_k127_2166535_20 Hydrolases of the alpha beta superfamily K06889 - - 0.0000003765 61.0
HKD1_k127_2166535_3 Asparaginyl-tRNA synthetase K01893 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 5.699e-246 765.0
HKD1_k127_2166535_4 cysteine synthase K01697 - 4.2.1.22 8.298e-204 644.0
HKD1_k127_2166535_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 613.0
HKD1_k127_2166535_6 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 604.0
HKD1_k127_2166535_7 cystathionine K01739,K01758 - 2.5.1.48,4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 580.0
HKD1_k127_2166535_8 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 562.0
HKD1_k127_2166535_9 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 520.0
HKD1_k127_2239668_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01535 - 3.6.3.2,3.6.3.6 0.0 1132.0
HKD1_k127_2239668_1 TIGRFAM ATP-dependent DNA helicase, RecQ family K03654 - 3.6.4.12 1.108e-279 872.0
HKD1_k127_2239668_10 MmgE/PrpD family K01720 - 4.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 380.0
HKD1_k127_2239668_11 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 350.0
HKD1_k127_2239668_12 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 324.0
HKD1_k127_2239668_13 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003314 286.0
HKD1_k127_2239668_14 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
HKD1_k127_2239668_15 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000005536 214.0
HKD1_k127_2239668_16 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000929 197.0
HKD1_k127_2239668_17 - - - - 0.000000000000000000000000000000000000005639 155.0
HKD1_k127_2239668_18 - - - - 0.0000000000000000000000000000000002766 142.0
HKD1_k127_2239668_19 HlyD family secretion protein K01993 - - 0.000000000000000000000000000008939 130.0
HKD1_k127_2239668_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.477e-233 739.0
HKD1_k127_2239668_20 Belongs to the UPF0312 family - - - 0.00000000000000000000000000006018 127.0
HKD1_k127_2239668_21 Peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000004994 119.0
HKD1_k127_2239668_22 - - - - 0.00000000000000001204 90.0
HKD1_k127_2239668_23 NMT1-like family K07080 - - 0.000000000000001101 87.0
HKD1_k127_2239668_24 Protein of unknwon function (DUF3008) - - - 0.000000000000935 71.0
HKD1_k127_2239668_25 - - - - 0.000006082 55.0
HKD1_k127_2239668_3 Aldehyde dehydrogenase family - - - 8.059e-213 673.0
HKD1_k127_2239668_4 Amino acid permease K03294 - - 4.573e-200 634.0
HKD1_k127_2239668_5 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 597.0
HKD1_k127_2239668_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K03918,K07250,K13524 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 565.0
HKD1_k127_2239668_7 Allophanate hydrolase subunit 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 428.0
HKD1_k127_2239668_8 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 380.0
HKD1_k127_2239668_9 PFAM Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 381.0
HKD1_k127_2244253_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006475 278.0
HKD1_k127_2244253_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000006669 175.0
HKD1_k127_2244253_2 - - - - 0.0000000000000000000000000000000000002756 148.0
HKD1_k127_2244253_3 - - - - 0.00000001291 61.0
HKD1_k127_2244253_4 - - - - 0.0003282 49.0
HKD1_k127_2289443_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 4.126e-291 909.0
HKD1_k127_2289443_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 612.0
HKD1_k127_2289443_2 Acetokinase family K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 456.0
HKD1_k127_2289443_3 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 340.0
HKD1_k127_2289443_4 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 309.0
HKD1_k127_2289443_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 304.0
HKD1_k127_2289443_6 phosphoglycolate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007779 275.0
HKD1_k127_2289443_7 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000271 254.0
HKD1_k127_2289443_8 - - - - 0.0000000000000000000000000000000000000000000001223 171.0
HKD1_k127_2289443_9 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000001261 162.0
HKD1_k127_2312441_0 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 474.0
HKD1_k127_2312441_1 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000000000000000000000000002161 196.0
HKD1_k127_2312441_2 PFAM Diacylglycerol kinase, catalytic - - - 0.00000000000007962 77.0
HKD1_k127_2335388_0 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 505.0
HKD1_k127_2335388_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 432.0
HKD1_k127_2335388_2 PFAM glutamine amidotransferase class-I K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005847 276.0
HKD1_k127_2335388_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000001001 139.0
HKD1_k127_2349633_0 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003457 278.0
HKD1_k127_2349633_1 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001363 246.0
HKD1_k127_2349633_2 PFAM outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000001069 221.0
HKD1_k127_2349633_3 Protein of unknown function (DUF520) - - - 0.000000000000000000000000000000000000000000000000000000001161 204.0
HKD1_k127_2349633_4 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000006938 169.0
HKD1_k127_2349633_5 magnesium chelatase K07391 - - 0.0000000000000000000000004049 106.0
HKD1_k127_2372295_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1680.0
HKD1_k127_2372295_1 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 1.061e-296 919.0
HKD1_k127_2372295_10 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 323.0
HKD1_k127_2372295_11 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 320.0
HKD1_k127_2372295_12 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 316.0
HKD1_k127_2372295_13 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 301.0
HKD1_k127_2372295_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005576 286.0
HKD1_k127_2372295_15 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001333 230.0
HKD1_k127_2372295_16 - - - - 0.000000000000000000000000000000000000000001806 161.0
HKD1_k127_2372295_17 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000004488 159.0
HKD1_k127_2372295_18 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.000000000000000000000000000000000003856 141.0
HKD1_k127_2372295_19 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000000000001044 127.0
HKD1_k127_2372295_2 Amidohydrolase family - - - 9.942e-265 830.0
HKD1_k127_2372295_20 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000003107 128.0
HKD1_k127_2372295_21 response to copper ion K07156,K14166 - - 0.00000000000000000000000003426 112.0
HKD1_k127_2372295_22 Methyltransferase FkbM domain - - - 0.000000000000000009449 94.0
HKD1_k127_2372295_23 Cupin - - - 0.0000000000000008844 82.0
HKD1_k127_2372295_24 Putative peptidoglycan binding domain - - - 0.000000000004861 68.0
HKD1_k127_2372295_3 Rhodanese domain protein K01069 - 3.1.2.6 1.384e-216 680.0
HKD1_k127_2372295_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 475.0
HKD1_k127_2372295_5 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 441.0
HKD1_k127_2372295_6 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 399.0
HKD1_k127_2372295_7 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 392.0
HKD1_k127_2372295_8 PFAM Mo-co oxidoreductase dimerisation domain K17225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 384.0
HKD1_k127_2372295_9 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 370.0
HKD1_k127_2376389_0 amino acid - - - 3.483e-237 749.0
HKD1_k127_2376389_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 1.08e-228 719.0
HKD1_k127_2376389_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 347.0
HKD1_k127_2376389_11 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002976 271.0
HKD1_k127_2376389_12 Transglycosylase associated protein - - - 0.00000000000000000000007326 100.0
HKD1_k127_2376389_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 578.0
HKD1_k127_2376389_3 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 570.0
HKD1_k127_2376389_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 510.0
HKD1_k127_2376389_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 499.0
HKD1_k127_2376389_6 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 447.0
HKD1_k127_2376389_7 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 414.0
HKD1_k127_2376389_8 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 389.0
HKD1_k127_2376389_9 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 363.0
HKD1_k127_2421313_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 576.0
HKD1_k127_2421313_1 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000272 251.0
HKD1_k127_2421313_2 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000007698 141.0
HKD1_k127_2640821_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 6.632e-242 757.0
HKD1_k127_2640821_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 340.0
HKD1_k127_2640821_10 TIGRFAM Glutaredoxin-like protein, YruB-family - - - 0.000000003175 61.0
HKD1_k127_2640821_12 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.0002758 45.0
HKD1_k127_2640821_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000005563 239.0
HKD1_k127_2640821_3 LexA DNA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000009276 221.0
HKD1_k127_2640821_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000004574 182.0
HKD1_k127_2640821_5 protein trimerization - - - 0.000000000000000000000000000000000000003981 155.0
HKD1_k127_2640821_6 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000000000000000508 134.0
HKD1_k127_2640821_7 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00000000000000000000000000000002443 134.0
HKD1_k127_2640821_8 membrane - - - 0.000000000000000000000000000001148 135.0
HKD1_k127_2640821_9 impB/mucB/samB family K14161 - - 0.0000000000000000502 88.0
HKD1_k127_2659251_0 Calcineurin-like phosphoesterase K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 382.0
HKD1_k127_2659251_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001671 255.0
HKD1_k127_2659251_2 Methylpurine-DNA glycosylase (MPG) - - - 0.0000000000000000000000000000000000000000000000000000000005919 207.0
HKD1_k127_2659251_3 Berberine and berberine like - - - 0.0000000000000000000000001005 109.0
HKD1_k127_2659251_4 energy transducer activity - - - 0.00006702 53.0
HKD1_k127_2757311_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1102.0
HKD1_k127_2757311_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000314 248.0
HKD1_k127_2838863_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1048.0
HKD1_k127_2838863_1 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 328.0
HKD1_k127_2838863_2 formate dehydrogenase (NAD+) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001511 255.0
HKD1_k127_2838863_3 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000004655 217.0
HKD1_k127_2838863_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000238 218.0
HKD1_k127_2838863_5 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000005407 138.0
HKD1_k127_2900889_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 504.0
HKD1_k127_2900889_1 PFAM glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 487.0
HKD1_k127_2900889_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 371.0
HKD1_k127_2900889_3 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 332.0
HKD1_k127_3024834_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1159.0
HKD1_k127_3024834_1 TIGRFAM 2-oxoglutarate dehydrogenase, E1 subunit K00164 - 1.2.4.2 0.0 1149.0
HKD1_k127_3024834_10 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 462.0
HKD1_k127_3024834_11 SMART helicase c2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 451.0
HKD1_k127_3024834_12 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 441.0
HKD1_k127_3024834_13 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 437.0
HKD1_k127_3024834_14 Penicillin binding protein transpeptidase domain K03587,K08384 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 441.0
HKD1_k127_3024834_15 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 421.0
HKD1_k127_3024834_16 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 405.0
HKD1_k127_3024834_17 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 382.0
HKD1_k127_3024834_18 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 363.0
HKD1_k127_3024834_19 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 360.0
HKD1_k127_3024834_2 Cell wall formation - - - 2.803e-297 932.0
HKD1_k127_3024834_20 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 332.0
HKD1_k127_3024834_21 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 325.0
HKD1_k127_3024834_22 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 327.0
HKD1_k127_3024834_23 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 322.0
HKD1_k127_3024834_24 PFAM permease YjgP YjgQ family protein K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006359 288.0
HKD1_k127_3024834_25 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003257 277.0
HKD1_k127_3024834_26 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001131 263.0
HKD1_k127_3024834_27 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001693 243.0
HKD1_k127_3024834_28 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000006206 213.0
HKD1_k127_3024834_29 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000886 182.0
HKD1_k127_3024834_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 4.255e-195 619.0
HKD1_k127_3024834_30 - - - - 0.00000000000000000000000000000000000000000000001124 176.0
HKD1_k127_3024834_31 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000007626 164.0
HKD1_k127_3024834_32 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000007883 152.0
HKD1_k127_3024834_33 DNA polymerase type-B family K02336 - 2.7.7.7 0.00000000000000000000000000000009769 133.0
HKD1_k127_3024834_34 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000005474 118.0
HKD1_k127_3024834_35 Belongs to the MraZ family K03925 - - 0.0000000000000005093 84.0
HKD1_k127_3024834_36 - - - - 0.00000000000002637 75.0
HKD1_k127_3024834_38 Lysin motif - - - 0.000000000001903 76.0
HKD1_k127_3024834_39 COG3209 Rhs family protein - - - 0.000002413 56.0
HKD1_k127_3024834_4 Poly A polymerase head domain K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 595.0
HKD1_k127_3024834_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 584.0
HKD1_k127_3024834_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 547.0
HKD1_k127_3024834_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 497.0
HKD1_k127_3024834_8 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 501.0
HKD1_k127_3024834_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 471.0
HKD1_k127_3047173_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 596.0
HKD1_k127_3047173_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 580.0
HKD1_k127_3047173_10 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 389.0
HKD1_k127_3047173_11 geranylgeranyl reductase activity K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 346.0
HKD1_k127_3047173_12 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 334.0
HKD1_k127_3047173_13 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 289.0
HKD1_k127_3047173_14 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000233 292.0
HKD1_k127_3047173_15 Peptidase family S41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001383 279.0
HKD1_k127_3047173_16 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001622 271.0
HKD1_k127_3047173_17 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000003954 245.0
HKD1_k127_3047173_18 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000006621 209.0
HKD1_k127_3047173_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000003385 199.0
HKD1_k127_3047173_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 498.0
HKD1_k127_3047173_20 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000001325 179.0
HKD1_k127_3047173_21 Acyl-ACP thioesterase K07107 - - 0.000000000000000000000000000000000000000000005651 166.0
HKD1_k127_3047173_22 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000001542 164.0
HKD1_k127_3047173_23 Transcriptional regulator - - - 0.000000000000000000000000000000000000000002216 160.0
HKD1_k127_3047173_24 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000000000000000000000000000003082 145.0
HKD1_k127_3047173_25 Sulfotransferase domain - - - 0.00000000000000000000000000000004962 138.0
HKD1_k127_3047173_26 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000001181 120.0
HKD1_k127_3047173_27 AMP binding - - - 0.0000000000000000000000003572 118.0
HKD1_k127_3047173_28 - - - - 0.0000000000000000000003252 98.0
HKD1_k127_3047173_29 Large extracellular alpha-helical protein - - - 0.00000000000000000003194 96.0
HKD1_k127_3047173_3 glutamate-cysteine ligase activity K06048 GO:0003674,GO:0003824,GO:0016874,GO:0016879 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 491.0
HKD1_k127_3047173_31 Cytochrome oxidase complex assembly protein 1 - - - 0.0000005352 53.0
HKD1_k127_3047173_32 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00002196 55.0
HKD1_k127_3047173_4 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 477.0
HKD1_k127_3047173_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 481.0
HKD1_k127_3047173_6 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 473.0
HKD1_k127_3047173_7 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 460.0
HKD1_k127_3047173_8 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 416.0
HKD1_k127_3047173_9 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 403.0
HKD1_k127_3063493_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.908e-204 648.0
HKD1_k127_3063493_1 Bacterial protein of unknown function (DUF853) - - - 2.377e-202 642.0
HKD1_k127_3063493_10 general secretion pathway protein - - - 0.00007105 46.0
HKD1_k127_3063493_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000002191 259.0
HKD1_k127_3063493_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000004195 168.0
HKD1_k127_3063493_4 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000001081 138.0
HKD1_k127_3063493_5 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000001582 123.0
HKD1_k127_3063493_6 - - - - 0.0000000000000000000000001146 109.0
HKD1_k127_3063493_7 Protein of unknown function (DUF1761) - - - 0.000000000000000005225 90.0
HKD1_k127_3066472_0 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 599.0
HKD1_k127_3066472_1 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 309.0
HKD1_k127_3066472_2 transporter - - - 0.000000000000000000000000131 115.0
HKD1_k127_3066472_3 Amidohydrolase family - - - 0.000000000000002767 77.0
HKD1_k127_3120293_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2258.0
HKD1_k127_3120293_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2186.0
HKD1_k127_3120293_10 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 538.0
HKD1_k127_3120293_11 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 523.0
HKD1_k127_3120293_12 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 497.0
HKD1_k127_3120293_13 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 487.0
HKD1_k127_3120293_14 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 489.0
HKD1_k127_3120293_15 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 438.0
HKD1_k127_3120293_16 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 431.0
HKD1_k127_3120293_17 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 423.0
HKD1_k127_3120293_18 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 414.0
HKD1_k127_3120293_19 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 388.0
HKD1_k127_3120293_2 ABC-2 type transporter - - - 0.0 1112.0
HKD1_k127_3120293_20 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 396.0
HKD1_k127_3120293_21 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 379.0
HKD1_k127_3120293_22 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 376.0
HKD1_k127_3120293_23 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 373.0
HKD1_k127_3120293_24 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 358.0
HKD1_k127_3120293_25 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 353.0
HKD1_k127_3120293_26 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 340.0
HKD1_k127_3120293_27 Predicted integral membrane protein (DUF2270) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 331.0
HKD1_k127_3120293_28 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 329.0
HKD1_k127_3120293_29 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 317.0
HKD1_k127_3120293_3 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 1.067e-282 885.0
HKD1_k127_3120293_30 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 310.0
HKD1_k127_3120293_31 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 302.0
HKD1_k127_3120293_32 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009161 304.0
HKD1_k127_3120293_33 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 297.0
HKD1_k127_3120293_34 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 286.0
HKD1_k127_3120293_35 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 294.0
HKD1_k127_3120293_36 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001303 259.0
HKD1_k127_3120293_37 Ankyrin repeats (3 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004585 271.0
HKD1_k127_3120293_39 PFAM Inward rectifier potassium channel K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000000001821 243.0
HKD1_k127_3120293_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.892e-227 725.0
HKD1_k127_3120293_40 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000003664 240.0
HKD1_k127_3120293_41 Alpha/beta hydrolase family K07020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000976 236.0
HKD1_k127_3120293_42 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000001476 231.0
HKD1_k127_3120293_43 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000003067 239.0
HKD1_k127_3120293_44 4-amino-4-deoxy-L-arabinose transferase activity K13687 - - 0.000000000000000000000000000000000000000000000000000000000000000004728 250.0
HKD1_k127_3120293_45 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000001543 229.0
HKD1_k127_3120293_46 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000001414 216.0
HKD1_k127_3120293_47 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000871 216.0
HKD1_k127_3120293_48 Glycine D-amino acid oxidases (deaminating) K00273 - 1.4.3.3 0.00000000000000000000000000000000000000000000000000000000002958 218.0
HKD1_k127_3120293_49 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000003573 211.0
HKD1_k127_3120293_5 Peptidase family M28 - - - 7.245e-221 704.0
HKD1_k127_3120293_50 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000001368 208.0
HKD1_k127_3120293_51 Cobalamin adenosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000004994 199.0
HKD1_k127_3120293_52 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000000000002638 186.0
HKD1_k127_3120293_53 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000024 168.0
HKD1_k127_3120293_54 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000007473 162.0
HKD1_k127_3120293_55 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000143 166.0
HKD1_k127_3120293_56 PFAM GYD family protein - - - 0.000000000000000000000000001879 113.0
HKD1_k127_3120293_57 GDYXXLXY protein - - - 0.000000000000000000000000008503 117.0
HKD1_k127_3120293_58 Dodecin K09165 - - 0.00000000000000000000000001007 112.0
HKD1_k127_3120293_59 - - - - 0.00000000000000000000001051 101.0
HKD1_k127_3120293_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.538e-218 681.0
HKD1_k127_3120293_60 - - - - 0.00000000000000000000001434 111.0
HKD1_k127_3120293_61 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000005397 101.0
HKD1_k127_3120293_62 SecE/Sec61-gamma subunits of protein translocation complex K03073 - - 0.000000000000000000002762 96.0
HKD1_k127_3120293_63 Predicted membrane protein (DUF2157) - - - 0.000000000000000000003436 102.0
HKD1_k127_3120293_64 - - - - 0.000000000000000000004511 94.0
HKD1_k127_3120293_65 Serine Threonine protein kinase K08884 - 2.7.11.1 0.00000000000000000001818 103.0
HKD1_k127_3120293_66 - - - - 0.00000000000000000001837 96.0
HKD1_k127_3120293_67 - - - - 0.0000000000000003375 84.0
HKD1_k127_3120293_7 Bacterial protein of unknown function (DUF885) - - - 6.625e-195 625.0
HKD1_k127_3120293_72 photosystem II stabilization - - - 0.0000000000001643 76.0
HKD1_k127_3120293_73 Transposase IS200 like K07491 - - 0.0000000000002273 76.0
HKD1_k127_3120293_74 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 2.7.1.202 0.000000000002571 73.0
HKD1_k127_3120293_77 - - - - 0.0000000203 56.0
HKD1_k127_3120293_78 Transporter - - - 0.00000002306 66.0
HKD1_k127_3120293_8 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 580.0
HKD1_k127_3120293_80 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases K03641 - - 0.000478 52.0
HKD1_k127_3120293_81 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0005003 45.0
HKD1_k127_3120293_82 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.0008714 46.0
HKD1_k127_3120293_9 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 539.0
HKD1_k127_3124641_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 532.0
HKD1_k127_3124641_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739 - 2.5.1.48 0.00000000000000000000000000000000000000003542 154.0
HKD1_k127_3124641_3 Transposase IS200 like K07491 - - 0.00000000000000000000006372 102.0
HKD1_k127_3170732_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.881e-211 672.0
HKD1_k127_3170732_1 PFAM Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 452.0
HKD1_k127_3170732_2 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000001944 125.0
HKD1_k127_3170732_3 - - - - 0.00000000001722 76.0
HKD1_k127_3170732_4 Peptidase family M54 - - - 0.0000007778 53.0
HKD1_k127_3178519_0 MacB-like periplasmic core domain - - - 2.491e-230 735.0
HKD1_k127_3178519_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 312.0
HKD1_k127_3178519_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003226 235.0
HKD1_k127_3178519_3 - - - - 0.000000000000000003905 91.0
HKD1_k127_3209819_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1250.0
HKD1_k127_3209819_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 5.628e-199 630.0
HKD1_k127_3209819_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000001916 122.0
HKD1_k127_3209819_11 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000005496 121.0
HKD1_k127_3209819_12 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000008182 120.0
HKD1_k127_3209819_13 Predicted membrane protein (DUF2127) - - - 0.00000000002168 71.0
HKD1_k127_3209819_14 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000002034 58.0
HKD1_k127_3209819_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 501.0
HKD1_k127_3209819_3 Phosphorylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 428.0
HKD1_k127_3209819_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 320.0
HKD1_k127_3209819_5 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000001371 241.0
HKD1_k127_3209819_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000002857 205.0
HKD1_k127_3209819_7 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000002581 175.0
HKD1_k127_3209819_8 - - - - 0.0000000000000000000000000000000000000000127 159.0
HKD1_k127_3209819_9 3D domain protein K21471 - - 0.0000000000000000000000000000000001222 139.0
HKD1_k127_3227655_0 Glycosyl transferase family 21 - - - 0.0 1047.0
HKD1_k127_3227655_1 Sortilin, neurotensin receptor 3, - - - 0.0 1038.0
HKD1_k127_3227655_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 442.0
HKD1_k127_3227655_11 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 410.0
HKD1_k127_3227655_12 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 403.0
HKD1_k127_3227655_13 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 403.0
HKD1_k127_3227655_14 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 376.0
HKD1_k127_3227655_15 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 333.0
HKD1_k127_3227655_16 Part of the ABC transporter complex LolCDE involved in the translocation of K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 324.0
HKD1_k127_3227655_17 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 309.0
HKD1_k127_3227655_18 Type II secretion system (T2SS), protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005304 267.0
HKD1_k127_3227655_19 PFAM UvrB UvrC protein K19411 - - 0.000000000000000000000000000000000000000000000000000000000000000007324 228.0
HKD1_k127_3227655_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1029.0
HKD1_k127_3227655_20 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000009288 209.0
HKD1_k127_3227655_22 - K06039 - - 0.00000000000000000000000000000000000000000000000000001877 191.0
HKD1_k127_3227655_24 - - - - 0.0000000000000000000000000000000000000000002989 164.0
HKD1_k127_3227655_25 Type II secretion system (T2SS), protein K - - - 0.0000000000000000000000000000000000000005178 160.0
HKD1_k127_3227655_26 Type II secretion system (T2SS), protein G K02456 - - 0.00000000000000000000000000000000005323 138.0
HKD1_k127_3227655_27 - - - - 0.000000000000000000000000000000001181 135.0
HKD1_k127_3227655_28 Methyltransferase domain - - - 0.000000000000000000000000000000004605 140.0
HKD1_k127_3227655_29 - - - - 0.000000000000000000000000000002337 127.0
HKD1_k127_3227655_3 with chaperone activity ATP-binding K03696 - - 6.9e-322 1004.0
HKD1_k127_3227655_30 Protein of unknown function (DUF2834) - - - 0.00000000000000000000000000000567 123.0
HKD1_k127_3227655_31 YjbR - - - 0.0000000000000000000000000002706 116.0
HKD1_k127_3227655_33 - - - - 0.000000000000000000000000237 113.0
HKD1_k127_3227655_34 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000282 103.0
HKD1_k127_3227655_35 SnoaL-like domain - - - 0.000000000000000006006 89.0
HKD1_k127_3227655_36 DUF167 K09131 - - 0.0000000000000001971 82.0
HKD1_k127_3227655_37 Virulence factor Mce family protein K02067 - - 0.000000000000002445 87.0
HKD1_k127_3227655_39 Cupin 2, conserved barrel domain protein - - - 0.000000000000611 76.0
HKD1_k127_3227655_4 Aminotransferase class-III K00819 - 2.6.1.13 1.975e-206 653.0
HKD1_k127_3227655_40 Pfam:UPF0118 - - - 0.000000000001654 78.0
HKD1_k127_3227655_42 Putative peptidoglycan binding domain - - - 0.000000009311 66.0
HKD1_k127_3227655_43 General secretion pathway protein K02459 - - 0.0000003097 60.0
HKD1_k127_3227655_44 - - - - 0.0000007653 56.0
HKD1_k127_3227655_5 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 610.0
HKD1_k127_3227655_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 532.0
HKD1_k127_3227655_7 Protein-arginine kinase K19405 - 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 524.0
HKD1_k127_3227655_8 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 490.0
HKD1_k127_3227655_9 GDP-mannose 4,6 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 488.0
HKD1_k127_3233947_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 1.369e-302 953.0
HKD1_k127_3271733_0 TLC ATP/ADP transporter K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000009903 231.0
HKD1_k127_3271733_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000002943 203.0
HKD1_k127_3271733_2 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000000001223 171.0
HKD1_k127_3271733_3 Cupin - - - 0.0000000000000000000000000004787 118.0
HKD1_k127_3271733_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000003816 102.0
HKD1_k127_3413089_0 KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 538.0
HKD1_k127_3413089_1 transferase activity, transferring glycosyl groups K00713,K06338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 444.0
HKD1_k127_3413089_11 - - - - 0.00000000005533 64.0
HKD1_k127_3413089_12 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000007917 63.0
HKD1_k127_3413089_2 PFAM ATP dependent DNA ligase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 436.0
HKD1_k127_3413089_3 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 421.0
HKD1_k127_3413089_4 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 419.0
HKD1_k127_3413089_5 PFAM Ribonuclease BN-like family K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009417 283.0
HKD1_k127_3413089_6 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000000002751 182.0
HKD1_k127_3413089_7 Domain of unknown function (DUF2383) - - - 0.0000000000000000000000000000000000000003575 154.0
HKD1_k127_3413089_8 - - - - 0.000000000000000000000000000000000000004305 152.0
HKD1_k127_3413089_9 - - - - 0.000000000000000000000001604 108.0
HKD1_k127_3421141_0 DNA ligase N terminus K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 5e-324 1014.0
HKD1_k127_3421141_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 571.0
HKD1_k127_3421141_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000007131 175.0
HKD1_k127_3421141_11 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000000000000000000000000000000007238 175.0
HKD1_k127_3421141_12 - - - - 0.0000000000000000000000000000000003975 135.0
HKD1_k127_3421141_13 - - - - 0.00000000000000000000000000000003709 134.0
HKD1_k127_3421141_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 519.0
HKD1_k127_3421141_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 463.0
HKD1_k127_3421141_4 Putative citrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009435 393.0
HKD1_k127_3421141_5 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 338.0
HKD1_k127_3421141_6 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 306.0
HKD1_k127_3421141_7 Integral membrane protein TerC family K05794 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 300.0
HKD1_k127_3421141_8 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000003142 240.0
HKD1_k127_3421141_9 tRNA (Uracil-5-)-methyltransferase K03215,K15331 - 2.1.1.190,2.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000006016 240.0
HKD1_k127_350042_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 499.0
HKD1_k127_3536020_0 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 435.0
HKD1_k127_3536020_1 Zinc-uptake complex component A periplasmic K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003104 286.0
HKD1_k127_3536020_2 ABC 3 transport family K02075,K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001594 260.0
HKD1_k127_3536020_3 major outer membrane lipoprotein - - - 0.0000000000000000000000003781 113.0
HKD1_k127_3623140_0 Glycosyltransferase Family 4 - - - 1.763e-222 715.0
HKD1_k127_3623140_1 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 6.551e-205 651.0
HKD1_k127_3623140_2 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 486.0
HKD1_k127_3623140_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 372.0
HKD1_k127_3623140_4 Ornithine cyclodeaminase/mu-crystallin family K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 326.0
HKD1_k127_3623140_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008991 259.0
HKD1_k127_3623140_6 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.00000000000000000000000000000000000000000000000000000000000000005237 233.0
HKD1_k127_3623140_7 EVE domain - - - 0.00000000000000000000000000000000000000000000001075 178.0
HKD1_k127_3623140_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000001362 88.0
HKD1_k127_3631192_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 384.0
HKD1_k127_3631192_1 tRNA (Guanine-1)-methyltransferase K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 312.0
HKD1_k127_3631192_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000005743 144.0
HKD1_k127_3631192_3 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000008369 121.0
HKD1_k127_3631192_4 Belongs to the UPF0109 family K06960 - - 0.000000000000000000009778 94.0
HKD1_k127_3634690_0 Glycoside hydrolase - - - 1.29e-232 734.0
HKD1_k127_3634690_1 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 440.0
HKD1_k127_3634690_2 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008495 278.0
HKD1_k127_3634690_3 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004613 274.0
HKD1_k127_3634690_4 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000000005368 206.0
HKD1_k127_3634690_6 HemY domain protein - - - 0.0000000000000000000000000000000000235 154.0
HKD1_k127_3634690_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000002298 141.0
HKD1_k127_3634690_8 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000326 144.0
HKD1_k127_3662398_0 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 473.0
HKD1_k127_3662398_1 Domain of unknown function (DUF4071) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 376.0
HKD1_k127_3662398_10 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000004054 145.0
HKD1_k127_3662398_11 Ribosomal protein S18 K02963 - - 0.00000000000000000000000000000000007694 134.0
HKD1_k127_3662398_12 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000000000002953 135.0
HKD1_k127_3662398_13 Ribosomal protein L33 K02913 - - 0.000000000000000001245 86.0
HKD1_k127_3662398_15 CAAX protease self-immunity - - - 0.000001591 59.0
HKD1_k127_3662398_16 Bacterial Ig-like domain - - - 0.000001796 54.0
HKD1_k127_3662398_2 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 345.0
HKD1_k127_3662398_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 331.0
HKD1_k127_3662398_4 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 291.0
HKD1_k127_3662398_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002212 284.0
HKD1_k127_3662398_6 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000000000008044 229.0
HKD1_k127_3662398_7 Addiction module toxin, RelE StbE family - - - 0.00000000000000000000000000000000000000000000000001257 181.0
HKD1_k127_3662398_8 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000008305 169.0
HKD1_k127_3662398_9 Glycoprotease family - - - 0.0000000000000000000000000000000000000000003818 165.0
HKD1_k127_3664487_0 Erythromycin esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 578.0
HKD1_k127_3664487_1 - - - - 0.000000000000000000000000000000000000000000000002126 180.0
HKD1_k127_3664487_2 SMART ATP-binding region, ATPase-like - - - 0.0000000000006306 71.0
HKD1_k127_3664487_3 Universal stress protein - - - 0.000000000005988 67.0
HKD1_k127_3664487_4 S-layer homology domain - - - 0.00001476 52.0
HKD1_k127_3671125_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 454.0
HKD1_k127_3671125_1 - - - - 0.000000000000000000000000000000000000000000000000000001353 194.0
HKD1_k127_3671125_2 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000000000005464 127.0
HKD1_k127_3671125_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000005943 63.0
HKD1_k127_3726044_0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 373.0
HKD1_k127_3726044_1 PFAM glutathione-dependent formaldehyde-activating GFA - - - 0.000000000000000000000000000000000000000000000009755 174.0
HKD1_k127_3726044_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000336 151.0
HKD1_k127_3726044_3 - - - - 0.0000000000000000000000001616 113.0
HKD1_k127_391965_0 transferase K01027 - 2.8.3.5 1.309e-233 729.0
HKD1_k127_391965_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 389.0
HKD1_k127_391965_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000001604 125.0
HKD1_k127_393111_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 367.0
HKD1_k127_393111_1 CbiX K03795 - 4.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 332.0
HKD1_k127_393111_2 Cobalamin (vitamin B12) biosynthesis CbiX protein - - - 0.00000000000000000000000000000000000000000000000002377 187.0
HKD1_k127_393111_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000007201 135.0
HKD1_k127_393111_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.0000000000000000000187 97.0
HKD1_k127_40334_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1132.0
HKD1_k127_40334_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1108.0
HKD1_k127_40334_10 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003391 253.0
HKD1_k127_40334_11 - - - - 0.0000000000000000000000000000000000000000000000000000004072 196.0
HKD1_k127_40334_12 PFAM Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000001779 201.0
HKD1_k127_40334_13 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000000000000000000000000000005251 147.0
HKD1_k127_40334_14 major outer membrane lipoprotein - - - 0.000000000000000000000000004993 119.0
HKD1_k127_40334_15 SAM-dependent methyltransferase - - - 0.00000000000000000000000006885 113.0
HKD1_k127_40334_17 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000003206 80.0
HKD1_k127_40334_18 Putative auto-transporter adhesin, head GIN domain - - - 0.00000003409 63.0
HKD1_k127_40334_19 - - - - 0.0001239 53.0
HKD1_k127_40334_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 9.165e-220 688.0
HKD1_k127_40334_20 (SAM)-dependent - - - 0.0006046 45.0
HKD1_k127_40334_3 AI-2E family transporter - - - 1.666e-194 634.0
HKD1_k127_40334_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 517.0
HKD1_k127_40334_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 436.0
HKD1_k127_40334_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 430.0
HKD1_k127_40334_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 440.0
HKD1_k127_40334_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 345.0
HKD1_k127_40334_9 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009297 301.0
HKD1_k127_4039075_0 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 546.0
HKD1_k127_4039075_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 490.0
HKD1_k127_4039075_10 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000745 123.0
HKD1_k127_4039075_11 exo-alpha-(2->6)-sialidase activity - - - 0.000000009995 68.0
HKD1_k127_4039075_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 344.0
HKD1_k127_4039075_3 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 299.0
HKD1_k127_4039075_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002768 266.0
HKD1_k127_4039075_5 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000307 228.0
HKD1_k127_4039075_6 Domain of unknown function (DUF5069) - - - 0.000000000000000000000000000000000000000000000001012 179.0
HKD1_k127_4039075_7 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000009061 187.0
HKD1_k127_4039075_8 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000512 153.0
HKD1_k127_4039075_9 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000004119 148.0
HKD1_k127_4042262_0 Pup-ligase protein K13571 - 6.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 577.0
HKD1_k127_4063501_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 8.706e-200 629.0
HKD1_k127_4063501_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 572.0
HKD1_k127_4063501_10 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000005315 265.0
HKD1_k127_4063501_11 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000004887 260.0
HKD1_k127_4063501_12 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008822 264.0
HKD1_k127_4063501_13 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009081 244.0
HKD1_k127_4063501_14 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000005963 225.0
HKD1_k127_4063501_15 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000001574 213.0
HKD1_k127_4063501_16 ROK family K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000006195 169.0
HKD1_k127_4063501_17 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000436 167.0
HKD1_k127_4063501_18 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000004246 145.0
HKD1_k127_4063501_2 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 561.0
HKD1_k127_4063501_20 Response regulator, receiver K02657,K20972 - - 0.00000000000000000000000000000009827 137.0
HKD1_k127_4063501_21 ribosomal protein L31 K02909 - - 0.0000000000000000000000000000005866 122.0
HKD1_k127_4063501_22 Domain of unknown function (DUF4870) K09940 - - 0.0000000000000000000000000005474 118.0
HKD1_k127_4063501_24 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000166 101.0
HKD1_k127_4063501_25 Phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000009281 95.0
HKD1_k127_4063501_27 geranylgeranyl reductase activity K21401 - 1.3.99.38 0.0000000001598 64.0
HKD1_k127_4063501_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 475.0
HKD1_k127_4063501_4 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 465.0
HKD1_k127_4063501_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 428.0
HKD1_k127_4063501_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 412.0
HKD1_k127_4063501_7 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 388.0
HKD1_k127_4063501_8 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 290.0
HKD1_k127_4063501_9 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001278 283.0
HKD1_k127_4090776_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.152e-283 889.0
HKD1_k127_4090776_1 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 489.0
HKD1_k127_4090776_2 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 376.0
HKD1_k127_4090776_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000008344 240.0
HKD1_k127_4095324_0 PFAM peptidase M16 domain protein K07263 - - 5.931e-229 737.0
HKD1_k127_4095324_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 492.0
HKD1_k127_4095324_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 451.0
HKD1_k127_4095324_3 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006836 265.0
HKD1_k127_4095324_4 - - - - 0.000000000000000000000000000000000002061 144.0
HKD1_k127_4095324_5 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000001081 139.0
HKD1_k127_4108200_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 5.443e-198 624.0
HKD1_k127_4108200_1 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 518.0
HKD1_k127_4108200_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000006939 149.0
HKD1_k127_4108200_11 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000002698 127.0
HKD1_k127_4108200_12 - - - - 0.00000000000000000004652 96.0
HKD1_k127_4108200_2 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 492.0
HKD1_k127_4108200_3 Protein of unknown function (DUF2851) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 485.0
HKD1_k127_4108200_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 465.0
HKD1_k127_4108200_5 aminopeptidase activity K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 398.0
HKD1_k127_4108200_6 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009161 318.0
HKD1_k127_4108200_7 SRP54-type protein, GTPase domain K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 316.0
HKD1_k127_4108200_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000569 222.0
HKD1_k127_4108200_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000171 160.0
HKD1_k127_4117101_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1019.0
HKD1_k127_4117101_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 4.357e-203 649.0
HKD1_k127_4117101_10 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 309.0
HKD1_k127_4117101_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009472 295.0
HKD1_k127_4117101_12 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 283.0
HKD1_k127_4117101_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002598 274.0
HKD1_k127_4117101_14 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001184 258.0
HKD1_k127_4117101_16 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000000000000000000000000000000000000000000000000000008923 237.0
HKD1_k127_4117101_17 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000258 221.0
HKD1_k127_4117101_19 - - - - 0.0000000000000000000000000000000000000000000000000009799 199.0
HKD1_k127_4117101_2 Transglycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 567.0
HKD1_k127_4117101_20 integral membrane protein - - - 0.000000000000000000000000000000000000000000000005673 184.0
HKD1_k127_4117101_21 RNA recognition motif - - - 0.0000000000000000000000000000000000000000002787 166.0
HKD1_k127_4117101_22 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000007415 159.0
HKD1_k127_4117101_23 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000001373 157.0
HKD1_k127_4117101_24 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000001016 154.0
HKD1_k127_4117101_25 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000003444 116.0
HKD1_k127_4117101_27 - - - - 0.0000000000005049 80.0
HKD1_k127_4117101_28 Hydroxysteroid dehydrogenase like 2 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.000000000003184 72.0
HKD1_k127_4117101_29 Sulfotransferase domain - - - 0.000000009561 66.0
HKD1_k127_4117101_3 Major facilitator Superfamily K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 452.0
HKD1_k127_4117101_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 435.0
HKD1_k127_4117101_5 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007215 427.0
HKD1_k127_4117101_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 436.0
HKD1_k127_4117101_7 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 413.0
HKD1_k127_4117101_8 PFAM ABC-2 type transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 415.0
HKD1_k127_4117101_9 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 335.0
HKD1_k127_4142348_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 513.0
HKD1_k127_4142348_1 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 316.0
HKD1_k127_4142348_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 313.0
HKD1_k127_4142348_3 PFAM secretion protein HlyD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 301.0
HKD1_k127_4142348_4 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 286.0
HKD1_k127_4142348_5 PFAM Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 256.0
HKD1_k127_4142348_6 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000002733 150.0
HKD1_k127_4142348_7 COG0589 Universal stress protein UspA and related K14055 - - 0.00000000000000000000000000000007237 139.0
HKD1_k127_4142348_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000047 126.0
HKD1_k127_4211253_0 Tricorn protease C1 domain K08676 - - 0.0 1225.0
HKD1_k127_4211253_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 495.0
HKD1_k127_4211253_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004083 258.0
HKD1_k127_4211253_3 chromosome segregation - - - 0.000002514 57.0
HKD1_k127_4211253_4 excinuclease ABC - - - 0.0001919 44.0
HKD1_k127_4223412_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 6.573e-282 880.0
HKD1_k127_4223412_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 4.376e-263 829.0
HKD1_k127_4223412_10 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 446.0
HKD1_k127_4223412_11 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 432.0
HKD1_k127_4223412_12 oxidoreductase FAD NAD(P)-binding domain protein K00380 - 1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 427.0
HKD1_k127_4223412_13 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 418.0
HKD1_k127_4223412_14 Belongs to the amidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 374.0
HKD1_k127_4223412_15 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 337.0
HKD1_k127_4223412_16 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 310.0
HKD1_k127_4223412_17 Glycosyl hydrolases family 25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 296.0
HKD1_k127_4223412_18 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 293.0
HKD1_k127_4223412_19 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003399 285.0
HKD1_k127_4223412_2 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 7.117e-239 754.0
HKD1_k127_4223412_20 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003704 273.0
HKD1_k127_4223412_21 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009982 261.0
HKD1_k127_4223412_22 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004512 254.0
HKD1_k127_4223412_23 protein domain associated with K03595,K06883,K06946 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003665 252.0
HKD1_k127_4223412_24 Pfam:DUF59 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001162 234.0
HKD1_k127_4223412_25 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000001335 231.0
HKD1_k127_4223412_26 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000298 221.0
HKD1_k127_4223412_27 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000009081 206.0
HKD1_k127_4223412_28 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000001419 202.0
HKD1_k127_4223412_29 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000008932 189.0
HKD1_k127_4223412_3 Lysine-2,3-aminomutase - - - 3.155e-198 627.0
HKD1_k127_4223412_30 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000004141 179.0
HKD1_k127_4223412_31 Belongs to the amidase family - - - 0.0000000000000000000000000000000000000000000006979 175.0
HKD1_k127_4223412_32 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000005032 138.0
HKD1_k127_4223412_33 MobA-like NTP transferase domain - - - 0.0000000000000000000000000000000009645 137.0
HKD1_k127_4223412_34 Sugar (and other) transporter - - - 0.00000000000000000000005389 100.0
HKD1_k127_4223412_35 Protein of unknown function (DUF1016) - - - 0.0004742 44.0
HKD1_k127_4223412_36 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0006472 48.0
HKD1_k127_4223412_4 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 563.0
HKD1_k127_4223412_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 509.0
HKD1_k127_4223412_6 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 486.0
HKD1_k127_4223412_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 508.0
HKD1_k127_4223412_8 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 473.0
HKD1_k127_4223412_9 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 467.0
HKD1_k127_4303825_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 2.904e-307 969.0
HKD1_k127_4303825_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.865e-246 786.0
HKD1_k127_4303825_10 Protein kinase domain K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001335 279.0
HKD1_k127_4303825_11 SMART ATP-binding region, ATPase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001571 268.0
HKD1_k127_4303825_12 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006867 248.0
HKD1_k127_4303825_13 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000001686 224.0
HKD1_k127_4303825_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000009789 226.0
HKD1_k127_4303825_15 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000001227 226.0
HKD1_k127_4303825_16 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000000002203 218.0
HKD1_k127_4303825_17 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000005675 187.0
HKD1_k127_4303825_18 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000004324 179.0
HKD1_k127_4303825_19 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000001601 181.0
HKD1_k127_4303825_2 Belongs to the precorrin methyltransferase family K02303,K13542 - 2.1.1.107,4.2.1.75 3.753e-213 672.0
HKD1_k127_4303825_20 HTTM domain protein - - - 0.00000000000000000000000000000000000000000002917 173.0
HKD1_k127_4303825_21 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000009351 165.0
HKD1_k127_4303825_22 Ribosomal protein S21 - - - 0.000000000000000000000002731 102.0
HKD1_k127_4303825_23 Domain of unknown function (DUF5069) - - - 0.0000000000000000000002363 101.0
HKD1_k127_4303825_24 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00006493 48.0
HKD1_k127_4303825_25 - - - - 0.000666 50.0
HKD1_k127_4303825_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 494.0
HKD1_k127_4303825_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 436.0
HKD1_k127_4303825_6 Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 384.0
HKD1_k127_4303825_7 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 320.0
HKD1_k127_4303825_8 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 315.0
HKD1_k127_4303825_9 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001773 287.0
HKD1_k127_4313024_0 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 441.0
HKD1_k127_4313024_1 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 343.0
HKD1_k127_4313024_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005296 296.0
HKD1_k127_4313024_3 Adenylate cyclase - - - 0.00000000000000000000005162 101.0
HKD1_k127_4313024_4 - - - - 0.000000001319 68.0
HKD1_k127_4313024_5 Transcriptional regulatory protein, C terminal - - - 0.00000006736 56.0
HKD1_k127_431877_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 530.0
HKD1_k127_431877_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 514.0
HKD1_k127_431877_2 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 484.0
HKD1_k127_431877_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000677 270.0
HKD1_k127_431877_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00001213 51.0
HKD1_k127_4328143_0 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 1.426e-224 713.0
HKD1_k127_4328143_1 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 1.432e-207 663.0
HKD1_k127_4328143_10 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000001078 243.0
HKD1_k127_4328143_11 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000001594 235.0
HKD1_k127_4328143_12 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000006865 217.0
HKD1_k127_4328143_13 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000006131 195.0
HKD1_k127_4328143_14 HTH domain - - - 0.0000000000000000000000000000000001499 135.0
HKD1_k127_4328143_16 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000001327 126.0
HKD1_k127_4328143_17 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000002398 130.0
HKD1_k127_4328143_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000004964 102.0
HKD1_k127_4328143_19 23S rRNA-intervening sequence protein - - - 0.00000000000000000008984 103.0
HKD1_k127_4328143_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 546.0
HKD1_k127_4328143_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000009833 93.0
HKD1_k127_4328143_21 Domain of unknown function (DUF4349) - - - 0.000000000000001364 91.0
HKD1_k127_4328143_22 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.0000000008905 65.0
HKD1_k127_4328143_23 - - - - 0.00000008147 61.0
HKD1_k127_4328143_3 serine threonine protein kinase K00870,K12132 - 2.7.1.37,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 516.0
HKD1_k127_4328143_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 339.0
HKD1_k127_4328143_5 Methyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 325.0
HKD1_k127_4328143_6 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 324.0
HKD1_k127_4328143_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 301.0
HKD1_k127_4328143_8 40-residue YVTN family beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001858 299.0
HKD1_k127_4328143_9 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001487 253.0
HKD1_k127_4333277_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.886e-253 786.0
HKD1_k127_4333277_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.998e-250 782.0
HKD1_k127_4333277_10 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 474.0
HKD1_k127_4333277_11 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 446.0
HKD1_k127_4333277_12 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 428.0
HKD1_k127_4333277_13 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 402.0
HKD1_k127_4333277_14 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 392.0
HKD1_k127_4333277_15 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 342.0
HKD1_k127_4333277_16 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 325.0
HKD1_k127_4333277_17 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 326.0
HKD1_k127_4333277_18 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 319.0
HKD1_k127_4333277_19 pfam abc K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 303.0
HKD1_k127_4333277_2 PUA-like domain K00958 - 2.7.7.4 1.692e-248 781.0
HKD1_k127_4333277_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 297.0
HKD1_k127_4333277_21 Ku70/Ku80 beta-barrel domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 295.0
HKD1_k127_4333277_22 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001577 287.0
HKD1_k127_4333277_23 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001793 287.0
HKD1_k127_4333277_24 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004498 281.0
HKD1_k127_4333277_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002296 240.0
HKD1_k127_4333277_26 Helix-turn-helix diphteria tox regulatory element - - - 0.000000000000000000000000000000000000000000000000000000000219 206.0
HKD1_k127_4333277_27 - - - - 0.00000000000000000000000000000000000000000000000000075 188.0
HKD1_k127_4333277_28 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000001421 185.0
HKD1_k127_4333277_29 - - - - 0.0000000000000000000000000000000000000000000000001042 187.0
HKD1_k127_4333277_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.736e-246 767.0
HKD1_k127_4333277_30 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000000000000000000000000000003197 179.0
HKD1_k127_4333277_31 Universal stress protein family - - - 0.000000000000000000000000000000000000000002489 162.0
HKD1_k127_4333277_32 ATP synthase delta (OSCP) subunit K02113 - - 0.000000000000000000000000000000000000008629 149.0
HKD1_k127_4333277_33 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000002938 141.0
HKD1_k127_4333277_34 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000001345 134.0
HKD1_k127_4333277_35 Phosphopantetheine attachment site - - - 0.0000000000000000000000000007803 119.0
HKD1_k127_4333277_36 - - - - 0.000000000000000002544 92.0
HKD1_k127_4333277_37 ATP synthase subunit C K02110 - - 0.000000000000000005008 85.0
HKD1_k127_4333277_38 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000005271 83.0
HKD1_k127_4333277_4 H( )-stimulated, divalent metal cation uptake system K03322 - - 4.283e-230 719.0
HKD1_k127_4333277_5 7TM receptor with intracellular HD hydrolase K07037 - - 8.419e-201 640.0
HKD1_k127_4333277_6 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 567.0
HKD1_k127_4333277_7 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 556.0
HKD1_k127_4333277_8 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 524.0
HKD1_k127_4333277_9 glycine betaine transport K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 528.0
HKD1_k127_4481310_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 5.789e-280 873.0
HKD1_k127_4481310_1 Peptidase family M13 K07386 - - 1.237e-237 753.0
HKD1_k127_4481310_2 TamB, inner membrane protein subunit of TAM complex - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 580.0
HKD1_k127_4481310_3 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 510.0
HKD1_k127_4481310_4 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 449.0
HKD1_k127_4481310_5 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000003522 235.0
HKD1_k127_4481310_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000001959 166.0
HKD1_k127_4481310_7 protein conserved in bacteria K09973 - - 0.000000000000000000000000000006848 133.0
HKD1_k127_4481310_8 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000005305 75.0
HKD1_k127_4532235_0 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 384.0
HKD1_k127_4532235_1 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 321.0
HKD1_k127_4532235_2 protein disulfide oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003208 258.0
HKD1_k127_4532235_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003181 245.0
HKD1_k127_4532235_4 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000000000002028 156.0
HKD1_k127_4532235_5 (Rhomboid) family K19225 - 3.4.21.105 0.0000000000000000000000000000000002137 145.0
HKD1_k127_4532235_6 Tetratricopeptide repeat - - - 0.000003359 57.0
HKD1_k127_4575021_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 6.852e-248 778.0
HKD1_k127_4575021_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 4.977e-239 756.0
HKD1_k127_4575021_10 Domain of unknown function (DUF5069) - - - 0.0000000000000000000000000000000000000000001415 164.0
HKD1_k127_4575021_11 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000005819 144.0
HKD1_k127_4575021_14 - - - - 0.0000008996 57.0
HKD1_k127_4575021_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.815e-203 646.0
HKD1_k127_4575021_3 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 568.0
HKD1_k127_4575021_4 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 441.0
HKD1_k127_4575021_6 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 301.0
HKD1_k127_4575021_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 302.0
HKD1_k127_4575021_8 Methyltransferase fkbm family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 302.0
HKD1_k127_4575021_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002987 274.0
HKD1_k127_4608507_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1497.0
HKD1_k127_4608507_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 488.0
HKD1_k127_4608507_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002798 239.0
HKD1_k127_4608507_3 Fe-S metabolism associated domain K02426 - - 0.0000000000000000000000000000000000000000000000000000000000008936 213.0
HKD1_k127_4608507_4 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000006803 208.0
HKD1_k127_4608507_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000009765 145.0
HKD1_k127_4608507_6 HemY domain protein - - - 0.0000000000000000000000000000001078 135.0
HKD1_k127_4608507_7 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000008799 69.0
HKD1_k127_4608507_8 Copper binding proteins, plastocyanin/azurin family - - - 0.00005102 52.0
HKD1_k127_4823118_0 carbohydrate binding K13688 - - 0.0 2788.0
HKD1_k127_4823118_1 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001012 106.0
HKD1_k127_4908373_0 Cytochrome c - - - 9.622e-236 750.0
HKD1_k127_4908373_1 catalase activity - - - 6.255e-198 623.0
HKD1_k127_4908373_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 536.0
HKD1_k127_4908373_3 iron assimilation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 427.0
HKD1_k127_4908373_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 295.0
HKD1_k127_4908373_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005475 222.0
HKD1_k127_4918294_0 Sortilin, neurotensin receptor 3, - - - 0.0 1300.0
HKD1_k127_4918294_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.244e-276 860.0
HKD1_k127_4918294_10 PHP-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 347.0
HKD1_k127_4918294_11 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 341.0
HKD1_k127_4918294_12 Glycosyltransferase Family 4 K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 336.0
HKD1_k127_4918294_13 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 326.0
HKD1_k127_4918294_14 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 315.0
HKD1_k127_4918294_15 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 310.0
HKD1_k127_4918294_16 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 298.0
HKD1_k127_4918294_17 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001121 289.0
HKD1_k127_4918294_18 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007371 278.0
HKD1_k127_4918294_19 Histidinol phosphatase and related hydrolases of the PHP family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003713 277.0
HKD1_k127_4918294_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 5.293e-205 647.0
HKD1_k127_4918294_20 acetyltransferase, isoleucine patch superfamily K03818 GO:0003674,GO:0003824,GO:0008374,GO:0016740,GO:0016746,GO:0016747 - 0.000000000000000000000000000000000000000000000000000000000000000000000000009622 254.0
HKD1_k127_4918294_21 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000001578 257.0
HKD1_k127_4918294_22 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003641 241.0
HKD1_k127_4918294_24 Tetratricopeptide TPR_2 repeat protein K05807 - - 0.00000000000000000000000000000000000000000000000000000000001017 222.0
HKD1_k127_4918294_25 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000611 217.0
HKD1_k127_4918294_26 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000006569 196.0
HKD1_k127_4918294_27 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000003453 170.0
HKD1_k127_4918294_28 MoaC family - - - 0.00000000000000000000000000000000000000000002196 167.0
HKD1_k127_4918294_29 Lipopolysaccharide-assembly - - - 0.0000000000000000000000000000000000000000001594 165.0
HKD1_k127_4918294_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 620.0
HKD1_k127_4918294_30 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000004191 160.0
HKD1_k127_4918294_31 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000004971 138.0
HKD1_k127_4918294_32 Tetratricopeptide repeat - - - 0.00000000000000000000000000000009997 135.0
HKD1_k127_4918294_33 antisigma factor binding K04749 - - 0.000000000000000000000000000007288 122.0
HKD1_k127_4918294_34 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000005813 115.0
HKD1_k127_4918294_35 Intracellular proteinase inhibitor - - - 0.0000000000000000000000004601 112.0
HKD1_k127_4918294_37 23S rRNA-intervening sequence protein - - - 0.0000000000000000009532 86.0
HKD1_k127_4918294_38 MacB-like periplasmic core domain - - - 0.0000000000000008844 82.0
HKD1_k127_4918294_39 - - - - 0.00000000000003457 78.0
HKD1_k127_4918294_4 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 557.0
HKD1_k127_4918294_40 23S rRNA-intervening sequence protein - - - 0.0000000000002331 74.0
HKD1_k127_4918294_41 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000002848 78.0
HKD1_k127_4918294_42 - - - - 0.0000000002711 66.0
HKD1_k127_4918294_43 efflux transmembrane transporter activity - - - 0.000001109 56.0
HKD1_k127_4918294_44 Glycine-zipper domain - - - 0.000001522 55.0
HKD1_k127_4918294_45 efflux transmembrane transporter activity - - - 0.000006558 49.0
HKD1_k127_4918294_5 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 542.0
HKD1_k127_4918294_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 461.0
HKD1_k127_4918294_7 lipid A export permease ATP-binding protein MsbA K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 436.0
HKD1_k127_4918294_8 Molybdenum Cofactor Synthesis C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 381.0
HKD1_k127_4918294_9 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 363.0
HKD1_k127_494723_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 606.0
HKD1_k127_494723_1 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 321.0
HKD1_k127_494723_2 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004192 278.0
HKD1_k127_494723_3 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009178 276.0
HKD1_k127_494723_4 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000001695 98.0
HKD1_k127_505041_0 DEAD/H associated K03724 - - 0.0 1602.0
HKD1_k127_505041_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 5.963e-274 863.0
HKD1_k127_505041_10 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 458.0
HKD1_k127_505041_11 CHASE2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 388.0
HKD1_k127_505041_12 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 373.0
HKD1_k127_505041_13 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 321.0
HKD1_k127_505041_14 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 299.0
HKD1_k127_505041_15 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005124 275.0
HKD1_k127_505041_16 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000143 251.0
HKD1_k127_505041_17 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000004826 207.0
HKD1_k127_505041_18 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000004326 173.0
HKD1_k127_505041_19 - - - - 0.00000000000000000000000000000000000000000008149 168.0
HKD1_k127_505041_2 TIGRFAM ribonuclease, Rne Rng family K08301 - - 2.346e-257 801.0
HKD1_k127_505041_20 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000001769 140.0
HKD1_k127_505041_21 - - - - 0.0000000000000000000002763 102.0
HKD1_k127_505041_24 ClpP class K07403 - - 0.000000000002142 68.0
HKD1_k127_505041_25 Mammalian cell entry related domain protein K02067 - - 0.00000000444 68.0
HKD1_k127_505041_26 Putative peptidoglycan binding domain - - - 0.00001386 53.0
HKD1_k127_505041_27 thiamine biosynthesis protein ThiS K03154 - - 0.0001461 47.0
HKD1_k127_505041_3 Type II/IV secretion system protein - - - 8.698e-233 733.0
HKD1_k127_505041_4 Mur ligase middle domain protein K02558 - 6.3.2.45 2.179e-204 645.0
HKD1_k127_505041_5 B3/4 domain K01890 - 6.1.1.20 4.159e-203 658.0
HKD1_k127_505041_6 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 560.0
HKD1_k127_505041_7 Bacterial type II/III secretion system short domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 576.0
HKD1_k127_505041_8 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 546.0
HKD1_k127_505041_9 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 495.0
HKD1_k127_5063385_0 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 528.0
HKD1_k127_5063385_1 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 317.0
HKD1_k127_5063385_2 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003082 271.0
HKD1_k127_5063385_3 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002059 259.0
HKD1_k127_5063385_4 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000005417 212.0
HKD1_k127_5063385_5 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000001754 155.0
HKD1_k127_5063385_6 NUDIX hydrolase - - - 0.000000000000000739 78.0
HKD1_k127_5063385_7 Integral membrane protein TerC family - - - 0.00000000000001123 78.0
HKD1_k127_5071979_0 SMART Elongator protein 3 MiaB NifB K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 470.0
HKD1_k127_5071979_1 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 346.0
HKD1_k127_5071979_2 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003967 282.0
HKD1_k127_5071979_3 radical SAM domain protein K06138 - - 0.00000000000002026 78.0
HKD1_k127_5077317_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 358.0
HKD1_k127_5077317_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 327.0
HKD1_k127_5077317_2 Dihydrodipicolinate reductase, N-terminus K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000002738 235.0
HKD1_k127_5077317_3 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000001923 169.0
HKD1_k127_5077317_4 OmpA family - - - 0.00000000000000000000000001213 122.0
HKD1_k127_5077317_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000001681 59.0
HKD1_k127_5077317_6 Prokaryotic N-terminal methylation motif - - - 0.00001043 51.0
HKD1_k127_5091439_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 421.0
HKD1_k127_5091439_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 366.0
HKD1_k127_5091439_2 Family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009618 357.0
HKD1_k127_5091439_3 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 313.0
HKD1_k127_5091439_4 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000002907 251.0
HKD1_k127_5091439_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000003906 236.0
HKD1_k127_5091439_6 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000004567 174.0
HKD1_k127_5091439_7 Stress responsive A/B Barrel Domain - - - 0.000000000000000000000000000000000003548 140.0
HKD1_k127_5091439_8 methyltransferase - - - 0.000000000000000000000000003172 121.0
HKD1_k127_5117824_0 beta-galactosidase activity - - - 9.249e-201 641.0
HKD1_k127_5117824_1 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 331.0
HKD1_k127_5117824_2 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000004451 135.0
HKD1_k127_5117824_3 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000006041 131.0
HKD1_k127_5125552_0 PFAM Asparagine synthase K01953 - 6.3.5.4 4.18e-219 697.0
HKD1_k127_5125552_1 Permease family K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 570.0
HKD1_k127_5125552_2 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 366.0
HKD1_k127_5125552_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001347 297.0
HKD1_k127_5125552_4 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000000001681 151.0
HKD1_k127_51294_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.216e-291 917.0
HKD1_k127_51294_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 5.333e-226 708.0
HKD1_k127_51294_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000003438 173.0
HKD1_k127_51294_11 Domain of unknown function (DUF4203) - - - 0.00000000000000000000000009866 113.0
HKD1_k127_51294_13 TPR repeat - - - 0.000000000000000000001763 100.0
HKD1_k127_51294_14 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000005085 96.0
HKD1_k127_51294_15 - - - - 0.000000002143 63.0
HKD1_k127_51294_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.213e-221 695.0
HKD1_k127_51294_3 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 9.055e-204 644.0
HKD1_k127_51294_4 L-lactate dehydrogenase K00101,K16422 - 1.1.2.3,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 497.0
HKD1_k127_51294_5 MOSC domain containing protein K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 334.0
HKD1_k127_51294_6 Fungal family of unknown function (DUF1776) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 314.0
HKD1_k127_51294_7 Carbonic anhydrase - - - 0.000000000000000000000000000000000000000000000000000000000000000009925 233.0
HKD1_k127_51294_8 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000186 205.0
HKD1_k127_51294_9 Belongs to the P(II) protein family - - - 0.00000000000000000000000000000000000000000000000000009232 188.0
HKD1_k127_5153630_0 ATP-dependent DNA helicase activity K16898 - 3.6.4.12 1.175e-270 868.0
HKD1_k127_5153630_10 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000000000000004621 166.0
HKD1_k127_5153630_11 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000008679 136.0
HKD1_k127_5153630_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000002042 133.0
HKD1_k127_5153630_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000001641 86.0
HKD1_k127_5153630_14 Major Facilitator - - - 0.00002409 48.0
HKD1_k127_5153630_15 Outer membrane efflux protein - - - 0.00008276 55.0
HKD1_k127_5153630_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 538.0
HKD1_k127_5153630_3 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 400.0
HKD1_k127_5153630_4 selenocysteine insertion sequence binding K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 351.0
HKD1_k127_5153630_5 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 301.0
HKD1_k127_5153630_6 ATPases associated with a variety of cellular activities K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003931 268.0
HKD1_k127_5153630_7 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.000000000000000000000000000000000000000000000000000000000000000000000002102 258.0
HKD1_k127_5153630_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005889 257.0
HKD1_k127_5153630_9 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000001012 176.0
HKD1_k127_5199937_0 cellulose binding - - - 1.364e-252 809.0
HKD1_k127_5199937_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 3.378e-209 662.0
HKD1_k127_5199937_10 Lysin motif - - - 0.000000000000000000000000000000000000000000002395 173.0
HKD1_k127_5199937_11 - - - - 0.000000000000000000000000000000000000000001036 161.0
HKD1_k127_5199937_12 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000001737 162.0
HKD1_k127_5199937_13 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000003692 150.0
HKD1_k127_5199937_14 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000003652 130.0
HKD1_k127_5199937_15 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000001822 105.0
HKD1_k127_5199937_16 Putative peptidoglycan binding domain - - - 0.0000000000000000000001072 108.0
HKD1_k127_5199937_17 cell redox homeostasis - - - 0.0000000000003078 78.0
HKD1_k127_5199937_18 Domain of unknown function (DUF4404) - - - 0.000000000001608 74.0
HKD1_k127_5199937_19 DoxX family K15977 - - 0.000001858 54.0
HKD1_k127_5199937_2 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 551.0
HKD1_k127_5199937_20 methylamine metabolic process K03885,K16937 - 1.6.99.3,1.8.5.2 0.00001405 51.0
HKD1_k127_5199937_21 PFAM YHS domain - - - 0.0004779 51.0
HKD1_k127_5199937_3 UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 526.0
HKD1_k127_5199937_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 484.0
HKD1_k127_5199937_5 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 443.0
HKD1_k127_5199937_6 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K17736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 377.0
HKD1_k127_5199937_7 Glycoside-hydrolase family GH114 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 322.0
HKD1_k127_5199937_8 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 321.0
HKD1_k127_5199937_9 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 299.0
HKD1_k127_5204263_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2427.0
HKD1_k127_5204263_1 TIGRFAM FeS assembly protein SufB K09014 - - 5.776e-268 828.0
HKD1_k127_5204263_10 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 358.0
HKD1_k127_5204263_11 PFAM LOR SDH bifunctional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 352.0
HKD1_k127_5204263_12 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 338.0
HKD1_k127_5204263_13 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 344.0
HKD1_k127_5204263_14 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 343.0
HKD1_k127_5204263_15 Fungal chitosanase of glycosyl hydrolase group 75 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 338.0
HKD1_k127_5204263_16 Amidinotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 306.0
HKD1_k127_5204263_17 Oxidoreductase molybdopterin binding domain K00387,K07147 - 1.8.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 307.0
HKD1_k127_5204263_18 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001113 274.0
HKD1_k127_5204263_19 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004755 246.0
HKD1_k127_5204263_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.977e-264 825.0
HKD1_k127_5204263_20 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000004506 237.0
HKD1_k127_5204263_21 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000000000000006841 231.0
HKD1_k127_5204263_22 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000001931 214.0
HKD1_k127_5204263_23 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02841,K02843,K02849,K12982 - - 0.0000000000000000000000000000000000000000000000000000000001357 218.0
HKD1_k127_5204263_24 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000002809 162.0
HKD1_k127_5204263_25 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000001005 151.0
HKD1_k127_5204263_26 Rhomboid family - - - 0.0000000000000000000000000000000000001856 152.0
HKD1_k127_5204263_27 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000001001 136.0
HKD1_k127_5204263_28 - - - - 0.000000000000000000000000000000000468 151.0
HKD1_k127_5204263_29 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000001159 134.0
HKD1_k127_5204263_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.933e-242 772.0
HKD1_k127_5204263_32 Transmembrane proteins 14C - - - 0.0000000007199 64.0
HKD1_k127_5204263_33 Evidence 5 No homology to any previously reported sequences K14194,K21449 - - 0.00000005551 66.0
HKD1_k127_5204263_4 DNA polymerase X family K02347 - - 2.093e-227 721.0
HKD1_k127_5204263_5 Fumarase C C-terminus - - - 2.152e-199 634.0
HKD1_k127_5204263_6 PFAM NAD-dependent epimerase dehydratase K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 550.0
HKD1_k127_5204263_7 FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 502.0
HKD1_k127_5204263_8 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 418.0
HKD1_k127_5204263_9 ATPases associated with a variety of cellular activities K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 381.0
HKD1_k127_5217626_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 1.137e-209 659.0
HKD1_k127_5217626_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 571.0
HKD1_k127_5217626_10 3D domain - - - 0.000000000000000000000000000000000000000000000003123 182.0
HKD1_k127_5217626_11 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000004274 149.0
HKD1_k127_5217626_12 O-methyltransferase K00588 - 2.1.1.104 0.00000002457 66.0
HKD1_k127_5217626_2 glutamate-cysteine ligase activity K06048 GO:0003674,GO:0003824,GO:0016874,GO:0016879 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 475.0
HKD1_k127_5217626_3 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 413.0
HKD1_k127_5217626_4 glutamate-cysteine ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 396.0
HKD1_k127_5217626_5 Dihydroorotate dehydrogenase K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 383.0
HKD1_k127_5217626_6 Multicopper oxidase K06324 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 387.0
HKD1_k127_5217626_7 TIGRFAM SUF system FeS assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005907 239.0
HKD1_k127_5217626_8 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000000000000000000000000008185 225.0
HKD1_k127_5217626_9 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000001732 207.0
HKD1_k127_5225142_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 450.0
HKD1_k127_5225142_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 351.0
HKD1_k127_5225142_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 314.0
HKD1_k127_5225142_3 general secretion pathway protein K02456 - - 0.000000001565 68.0
HKD1_k127_5244633_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1178.0
HKD1_k127_5244633_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 1.022e-230 728.0
HKD1_k127_5244633_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 430.0
HKD1_k127_5244633_11 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 412.0
HKD1_k127_5244633_12 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 449.0
HKD1_k127_5244633_13 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 381.0
HKD1_k127_5244633_14 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 372.0
HKD1_k127_5244633_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 381.0
HKD1_k127_5244633_16 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 346.0
HKD1_k127_5244633_17 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009786 328.0
HKD1_k127_5244633_18 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 329.0
HKD1_k127_5244633_19 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 332.0
HKD1_k127_5244633_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.778e-211 677.0
HKD1_k127_5244633_20 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 327.0
HKD1_k127_5244633_21 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 330.0
HKD1_k127_5244633_22 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 299.0
HKD1_k127_5244633_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001392 281.0
HKD1_k127_5244633_24 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001364 275.0
HKD1_k127_5244633_25 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004795 304.0
HKD1_k127_5244633_26 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006289 275.0
HKD1_k127_5244633_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008478 248.0
HKD1_k127_5244633_28 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000002596 237.0
HKD1_k127_5244633_29 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000001262 233.0
HKD1_k127_5244633_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 4.028e-209 657.0
HKD1_k127_5244633_30 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000006122 229.0
HKD1_k127_5244633_31 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000008089 191.0
HKD1_k127_5244633_32 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000000000004536 187.0
HKD1_k127_5244633_33 Domain of unknown function (DUF4347) - - - 0.0000000000000000000000000000000000000000000000007799 201.0
HKD1_k127_5244633_34 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000001159 186.0
HKD1_k127_5244633_35 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000003625 182.0
HKD1_k127_5244633_36 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000002325 175.0
HKD1_k127_5244633_37 YacP-like NYN domain K06962 - - 0.000000000000000000000000000000000000000003104 159.0
HKD1_k127_5244633_39 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000001053 143.0
HKD1_k127_5244633_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 585.0
HKD1_k127_5244633_40 Yqey-like protein K09117 - - 0.000000000000000000000000000003966 124.0
HKD1_k127_5244633_41 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000005115 123.0
HKD1_k127_5244633_42 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000003124 126.0
HKD1_k127_5244633_43 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000001546 101.0
HKD1_k127_5244633_44 Conserved repeat domain - - - 0.00000000000000000001288 109.0
HKD1_k127_5244633_45 nuclear chromosome segregation - - - 0.0000000000000000004298 98.0
HKD1_k127_5244633_46 SPW repeat - - - 0.00000000000000003305 87.0
HKD1_k127_5244633_48 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000526 64.0
HKD1_k127_5244633_49 G8 - - - 0.000002926 61.0
HKD1_k127_5244633_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 544.0
HKD1_k127_5244633_50 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00002902 50.0
HKD1_k127_5244633_51 Glutathione S-transferase, N-terminal domain K07393 - 1.8.5.7 0.00008419 48.0
HKD1_k127_5244633_6 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 552.0
HKD1_k127_5244633_7 NADH Ubiquinone plastoquinone (complex I) K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 552.0
HKD1_k127_5244633_8 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 452.0
HKD1_k127_5244633_9 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 438.0
HKD1_k127_5248655_0 Sortilin, neurotensin receptor 3, - - - 2.028e-308 966.0
HKD1_k127_5248655_1 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.000000000000000000000000000000000000000000000000000000000000000000003214 248.0
HKD1_k127_5248655_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000003049 171.0
HKD1_k127_5248655_3 SMART metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000002475 160.0
HKD1_k127_5253094_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 462.0
HKD1_k127_5253094_1 - - - - 0.000000000000000000000000000000000006878 150.0
HKD1_k127_5253094_2 Cytochrome c - - - 0.0000000000000006298 81.0
HKD1_k127_5253094_3 Cytochrome c - - - 0.000000000000004097 80.0
HKD1_k127_5291132_0 Bacterial capsule synthesis protein PGA_cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 335.0
HKD1_k127_5291132_1 Nicotine adenine dinucleotide glycohydrolase (NADase) - - - 0.000000000000000000000000000000000000000000000000000008235 207.0
HKD1_k127_5298043_0 PFAM magnesium chelatase ChlI subunit K07391 - - 7.857e-235 737.0
HKD1_k127_5298043_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000003105 77.0
HKD1_k127_5311340_0 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 580.0
HKD1_k127_5311340_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 476.0
HKD1_k127_5311340_10 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000000000001025 174.0
HKD1_k127_5311340_11 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000007078 169.0
HKD1_k127_5311340_12 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000000002592 150.0
HKD1_k127_5311340_13 Integral membrane protein (intg_mem_TP0381) - - - 0.000000000000000000000000000000000002708 148.0
HKD1_k127_5311340_14 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.00000000000000000000000000000000004891 138.0
HKD1_k127_5311340_15 Universal stress protein family - - - 0.0000000000000000000000000000000001646 145.0
HKD1_k127_5311340_16 Ribosomal L32p protein family K02911 - - 0.000000000000000000002363 94.0
HKD1_k127_5311340_17 - - - - 0.00000000000000007174 89.0
HKD1_k127_5311340_19 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000006976 58.0
HKD1_k127_5311340_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 444.0
HKD1_k127_5311340_3 2-dehydro-3-deoxyphosphooctonate aldolase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 400.0
HKD1_k127_5311340_4 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 374.0
HKD1_k127_5311340_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 373.0
HKD1_k127_5311340_6 PFAM Mg2 transporter protein CorA family protein K16074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 319.0
HKD1_k127_5311340_7 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 307.0
HKD1_k127_5311340_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000001677 236.0
HKD1_k127_5311340_9 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000009783 208.0
HKD1_k127_5337324_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1045.0
HKD1_k127_5337324_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 539.0
HKD1_k127_5337324_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000001249 169.0
HKD1_k127_5337324_11 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000001414 167.0
HKD1_k127_5337324_13 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000009566 139.0
HKD1_k127_5337324_14 Protein of unknown function (DUF3667) - - - 0.00000000000000000000000000001176 132.0
HKD1_k127_5337324_15 Mitochondrial biogenesis AIM24 - - - 0.0005435 52.0
HKD1_k127_5337324_2 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 449.0
HKD1_k127_5337324_3 5'-3' exonuclease K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 364.0
HKD1_k127_5337324_4 Involved in the tonB-independent uptake of proteins K03641,K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 343.0
HKD1_k127_5337324_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 312.0
HKD1_k127_5337324_6 serine-type peptidase activity K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001285 288.0
HKD1_k127_5337324_8 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000007818 181.0
HKD1_k127_5337324_9 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000005896 170.0
HKD1_k127_5379987_0 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 433.0
HKD1_k127_5379987_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 299.0
HKD1_k127_5379987_2 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000001026 236.0
HKD1_k127_5379987_3 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000001363 236.0
HKD1_k127_5379987_4 PFAM transposase IS116 IS110 IS902 family protein K07486 - - 0.000000000000000000000001483 108.0
HKD1_k127_5379987_5 - - - - 0.000000000000000000003002 106.0
HKD1_k127_5388066_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.366e-209 668.0
HKD1_k127_5388066_1 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 600.0
HKD1_k127_5388066_10 - - - - 0.000000000000000001022 90.0
HKD1_k127_5388066_11 Methylamine utilisation protein MauE - - - 0.0000000000000003139 85.0
HKD1_k127_5388066_12 Protein of unknown function (DUF3309) - - - 0.000000000001516 68.0
HKD1_k127_5388066_13 Trypsin - - - 0.00001349 57.0
HKD1_k127_5388066_2 Male sterility protein K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 417.0
HKD1_k127_5388066_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 310.0
HKD1_k127_5388066_4 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003883 245.0
HKD1_k127_5388066_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000754 175.0
HKD1_k127_5388066_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - 0.0000000000000000000000000000000000003238 147.0
HKD1_k127_5388066_7 Protein of unknown function (DUF1573) - - - 0.000000000000000000000000000005457 127.0
HKD1_k127_5388066_8 Rhodanese Homology Domain - - - 0.0000000000000000000000008212 109.0
HKD1_k127_5388066_9 CsbD-like - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000008778 98.0
HKD1_k127_5447190_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1405.0
HKD1_k127_5447190_1 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 6.002e-261 822.0
HKD1_k127_5447190_10 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 322.0
HKD1_k127_5447190_11 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 310.0
HKD1_k127_5447190_12 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 294.0
HKD1_k127_5447190_13 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004975 286.0
HKD1_k127_5447190_14 Squalene phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004856 279.0
HKD1_k127_5447190_15 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001736 268.0
HKD1_k127_5447190_16 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002376 254.0
HKD1_k127_5447190_17 DNA integration K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000001665 248.0
HKD1_k127_5447190_18 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000002178 258.0
HKD1_k127_5447190_19 Sh3 type 3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001635 239.0
HKD1_k127_5447190_2 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 2.661e-197 629.0
HKD1_k127_5447190_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000002627 222.0
HKD1_k127_5447190_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000001209 226.0
HKD1_k127_5447190_22 self proteolysis - - - 0.0000000000000000000000000000000000000000000000000000000000125 213.0
HKD1_k127_5447190_24 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000002117 210.0
HKD1_k127_5447190_25 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000001018 205.0
HKD1_k127_5447190_26 - - - - 0.000000000000000000000000000000000000000000000000003425 197.0
HKD1_k127_5447190_27 ACT domain protein - - - 0.0000000000000000000000000000000000000002834 155.0
HKD1_k127_5447190_28 Ami_3 - - - 0.00000000000000000000000000000000000001371 155.0
HKD1_k127_5447190_29 EamA-like transporter family K07790 - - 0.000000000000000000000000000000000003791 150.0
HKD1_k127_5447190_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 540.0
HKD1_k127_5447190_30 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001272 138.0
HKD1_k127_5447190_31 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000002727 116.0
HKD1_k127_5447190_32 Carbohydrate-selective porin, OprB family K16080 - - 0.000000000000000000001045 99.0
HKD1_k127_5447190_33 BetI-type transcriptional repressor, C-terminal - - - 0.000000000000000000007952 100.0
HKD1_k127_5447190_35 - - - - 0.000000000001886 72.0
HKD1_k127_5447190_36 - - - - 0.000000000004315 72.0
HKD1_k127_5447190_37 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' K03556 - - 0.000001799 60.0
HKD1_k127_5447190_38 Carbohydrate-selective porin, OprB family K16079,K16080 - - 0.00001179 52.0
HKD1_k127_5447190_4 Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 471.0
HKD1_k127_5447190_40 FecR protein - - - 0.0005313 51.0
HKD1_k127_5447190_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 467.0
HKD1_k127_5447190_6 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 - 1.14.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 438.0
HKD1_k127_5447190_7 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 426.0
HKD1_k127_5447190_8 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 424.0
HKD1_k127_5447190_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 360.0
HKD1_k127_5595292_0 type II secretion system protein E K02652 - - 3.776e-262 817.0
HKD1_k127_5595292_1 Proteasomal ATPase OB/ID domain K13527 - - 1.351e-251 787.0
HKD1_k127_5595292_2 Type II/IV secretion system protein K02652 - - 5.669e-204 649.0
HKD1_k127_5595292_3 type II secretion K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 531.0
HKD1_k127_5595292_4 general secretion pathway protein - - - 0.0000000000000000000000000000001047 132.0
HKD1_k127_5595292_5 Beta-lactamase superfamily domain - - - 0.00003175 51.0
HKD1_k127_5615878_0 PFAM cytochrome c assembly protein - - - 6.444e-198 636.0
HKD1_k127_5615878_1 ResB-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 342.0
HKD1_k127_5615878_2 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000003834 138.0
HKD1_k127_5636099_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 519.0
HKD1_k127_5636099_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 392.0
HKD1_k127_5636099_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000008844 237.0
HKD1_k127_5636099_3 NLP P60 protein - - - 0.0000000000000000000000000000000000000000000000004817 180.0
HKD1_k127_5636099_4 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000001122 150.0
HKD1_k127_5636099_5 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000001671 92.0
HKD1_k127_5636099_6 Endonuclease containing a URI domain K07461 - - 0.000000000000000003075 87.0
HKD1_k127_5636099_7 Belongs to the 'phage' integrase family - - - 0.000000000000005006 78.0
HKD1_k127_5673744_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 443.0
HKD1_k127_5673744_1 ABC transporter, substrate-binding protein, aliphatic sulfonates family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 409.0
HKD1_k127_5673744_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 385.0
HKD1_k127_5673744_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 383.0
HKD1_k127_5673744_4 Protein of unknown function (DUF1460) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 379.0
HKD1_k127_5673744_5 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000002009 176.0
HKD1_k127_5673744_6 - - - - 0.0000000000000000000000000000000000007916 156.0
HKD1_k127_5673744_7 Transcriptional regulator - - - 0.0000000000000000009793 89.0
HKD1_k127_5673744_8 GYD domain - - - 0.000000000000000004077 89.0
HKD1_k127_5673744_9 polysaccharide biosynthetic process - - - 0.00000000000000006959 88.0
HKD1_k127_5773996_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 461.0
HKD1_k127_5773996_1 negative regulation of quinolinate biosynthetic process K03392 GO:0001760,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006140,GO:0006520,GO:0006521,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009820,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016043,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019439,GO:0019752,GO:0022607,GO:0030808,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0033238,GO:0034641,GO:0042402,GO:0042430,GO:0042436,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043648,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046874,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051186,GO:0051193,GO:0051196,GO:0051259,GO:0062012,GO:0062014,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0072330,GO:0072524,GO:0072525,GO:0080090,GO:0090357,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902688,GO:1904984,GO:1904985,GO:1905003,GO:1905004,GO:1905012 4.1.1.45 0.0000000000000000000000006156 107.0
HKD1_k127_58278_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 563.0
HKD1_k127_58278_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 515.0
HKD1_k127_58278_10 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000001578 241.0
HKD1_k127_58278_11 Protein involved in outer membrane biogenesis K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000003159 248.0
HKD1_k127_58278_12 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000005791 228.0
HKD1_k127_58278_13 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000000001799 165.0
HKD1_k127_58278_14 Nucleotidyl transferase K07281 - 2.7.7.74 0.0000000000000000000000000000000000000000002249 170.0
HKD1_k127_58278_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000005158 165.0
HKD1_k127_58278_16 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000002539 141.0
HKD1_k127_58278_17 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000001498 141.0
HKD1_k127_58278_18 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000236 123.0
HKD1_k127_58278_19 CDP-alcohol phosphatidyltransferase - - - 0.000000000000007035 83.0
HKD1_k127_58278_2 Beta-eliminating lyase K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 462.0
HKD1_k127_58278_20 Protein of unknown function (DUF2723) - - - 0.0000000000001305 84.0
HKD1_k127_58278_21 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000003495 79.0
HKD1_k127_58278_22 - - - - 0.00006125 48.0
HKD1_k127_58278_3 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 414.0
HKD1_k127_58278_4 PFAM Three-deoxy-D-manno-octulosonic-acid transferase domain protein K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 380.0
HKD1_k127_58278_5 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 376.0
HKD1_k127_58278_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 328.0
HKD1_k127_58278_7 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 321.0
HKD1_k127_58278_8 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 306.0
HKD1_k127_58278_9 Diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 299.0
HKD1_k127_5862165_0 PA domain - - - 0.0 1371.0
HKD1_k127_5862165_1 Domain of unknown function K03737 - 1.2.7.1 0.0 1126.0
HKD1_k127_5862165_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 475.0
HKD1_k127_5862165_3 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 436.0
HKD1_k127_5862165_4 Belongs to the TPP enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 351.0
HKD1_k127_5863763_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1598.0
HKD1_k127_5873725_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1452.0
HKD1_k127_5873725_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.418e-260 810.0
HKD1_k127_5873725_2 FAD binding domain - - - 1.062e-231 721.0
HKD1_k127_5873725_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000001929 243.0
HKD1_k127_5873725_4 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005857 236.0
HKD1_k127_5873725_5 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000006546 243.0
HKD1_k127_5873725_7 lactoylglutathione lyase activity K11210 - - 0.0000000000000000000000001636 111.0
HKD1_k127_5998710_0 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 456.0
HKD1_k127_5998710_1 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000006096 271.0
HKD1_k127_5998710_2 PFAM Transketolase K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000008509 237.0
HKD1_k127_5998710_3 Phosphopantetheine attachment site - - - 0.0000000000000000000344 93.0
HKD1_k127_6039754_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 379.0
HKD1_k127_6039754_1 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 297.0
HKD1_k127_6039754_2 palmitoyl-(protein) hydrolase activity K06999,K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002513 243.0
HKD1_k127_6039754_3 Dodecin K09165 - - 0.000000000000000000000002748 103.0
HKD1_k127_6039754_4 nitroreductase - - - 0.000000004152 58.0
HKD1_k127_6063372_0 Peptidase S46 - - - 8.004e-257 810.0
HKD1_k127_6063372_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 603.0
HKD1_k127_6063372_10 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000001641 227.0
HKD1_k127_6063372_11 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000001433 211.0
HKD1_k127_6063372_12 membrane - - - 0.0000000000000000000000000000000000000000000000000000001184 202.0
HKD1_k127_6063372_13 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000001994 190.0
HKD1_k127_6063372_14 - - - - 0.000000000000000000000000000000000005969 146.0
HKD1_k127_6063372_15 DoxX - - - 0.0000000000000000000000000000000199 130.0
HKD1_k127_6063372_17 - - - - 0.0000000000000003183 90.0
HKD1_k127_6063372_18 COG0671 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.00000000004249 72.0
HKD1_k127_6063372_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 544.0
HKD1_k127_6063372_3 Ku70/Ku80 beta-barrel domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 352.0
HKD1_k127_6063372_4 PFAM beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 348.0
HKD1_k127_6063372_5 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002396 274.0
HKD1_k127_6063372_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000118 267.0
HKD1_k127_6063372_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001487 249.0
HKD1_k127_6063372_8 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000001744 238.0
HKD1_k127_6063372_9 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001696 231.0
HKD1_k127_6077678_0 Glycosyl hydrolase family 65, C-terminal domain - - - 0.0 1518.0
HKD1_k127_6077678_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 515.0
HKD1_k127_6077678_2 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 456.0
HKD1_k127_6077678_3 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 452.0
HKD1_k127_6077678_4 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000002485 167.0
HKD1_k127_6077678_5 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000002825 129.0
HKD1_k127_6077678_6 Alcohol dehydrogenase GroES domain protein K13953,K18382 - 1.1.1.1 0.0000000000000000000000000000008862 123.0
HKD1_k127_6077678_7 Short repeat of unknown function (DUF308) - - - 0.0000000000000000001117 98.0
HKD1_k127_6077678_8 SnoaL-like domain - - - 0.00000007387 59.0
HKD1_k127_6148657_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.127e-196 621.0
HKD1_k127_6148657_1 Male sterility protein K12454 - 5.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 530.0
HKD1_k127_6148657_10 dehydratase - - - 0.000000000000000000000000000000002383 133.0
HKD1_k127_6148657_12 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) - - - 0.0000000000000007507 81.0
HKD1_k127_6148657_13 Aspartyl protease - - - 0.000001752 61.0
HKD1_k127_6148657_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 361.0
HKD1_k127_6148657_3 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 316.0
HKD1_k127_6148657_4 Bacterial lipid A biosynthesis acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 310.0
HKD1_k127_6148657_5 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 299.0
HKD1_k127_6148657_6 Belongs to the GTP cyclohydrolase I type 2 NIF3 family K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009015 283.0
HKD1_k127_6148657_7 peptide-methionine (S)-S-oxide reductase activity K07304,K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000027 263.0
HKD1_k127_6148657_8 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000006567 244.0
HKD1_k127_6148657_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000004449 191.0
HKD1_k127_6155797_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 2.359e-231 725.0
HKD1_k127_6155797_1 Amidohydrolase family - - - 3.214e-230 725.0
HKD1_k127_6155797_10 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 302.0
HKD1_k127_6155797_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001814 293.0
HKD1_k127_6155797_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001232 261.0
HKD1_k127_6155797_13 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000006715 177.0
HKD1_k127_6155797_14 MatE - - - 0.00000000000000000000000000000000000000009158 156.0
HKD1_k127_6155797_15 GCN5 family acetyltransferase K22477 - 2.3.1.1 0.000000000000000000000000000000002875 133.0
HKD1_k127_6155797_16 - - - - 0.000000000000000000000000000005369 129.0
HKD1_k127_6155797_18 Belongs to the ompA family K03286 - - 0.000000000000000000004278 98.0
HKD1_k127_6155797_2 Beta-Casp domain K07576 - - 5.947e-197 623.0
HKD1_k127_6155797_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 465.0
HKD1_k127_6155797_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 445.0
HKD1_k127_6155797_5 aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 422.0
HKD1_k127_6155797_6 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 404.0
HKD1_k127_6155797_7 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 391.0
HKD1_k127_6155797_8 Possible lysine decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 377.0
HKD1_k127_6158733_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 2.37e-274 854.0
HKD1_k127_6158733_1 phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 478.0
HKD1_k127_6158733_2 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 334.0
HKD1_k127_6158733_3 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004869 273.0
HKD1_k127_6158733_4 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000006104 217.0
HKD1_k127_6158733_6 Putative peptidoglycan binding domain - - - 0.000003191 59.0
HKD1_k127_6203645_0 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 427.0
HKD1_k127_6203645_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 415.0
HKD1_k127_6203645_10 O-antigen ligase like membrane protein - - - 0.00000000000000000000001506 115.0
HKD1_k127_6203645_11 Protein conserved in bacteria K20920 - - 0.00000003136 59.0
HKD1_k127_6203645_2 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 345.0
HKD1_k127_6203645_3 sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 306.0
HKD1_k127_6203645_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 295.0
HKD1_k127_6203645_5 ATP ADP translocase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001051 239.0
HKD1_k127_6203645_6 Chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000002083 233.0
HKD1_k127_6203645_7 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000111 211.0
HKD1_k127_6203645_8 - - - - 0.000000000000000000000000000000000001759 144.0
HKD1_k127_6203645_9 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000006429 120.0
HKD1_k127_6211626_0 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 513.0
HKD1_k127_6211626_1 - - - - 0.0000000000000000000000000000000000000000000000000228 186.0
HKD1_k127_6254865_0 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 557.0
HKD1_k127_6254865_1 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 462.0
HKD1_k127_6254865_2 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 420.0
HKD1_k127_6254865_3 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 402.0
HKD1_k127_6254865_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 381.0
HKD1_k127_6254865_5 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003988 256.0
HKD1_k127_6254865_6 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 0.000000000000000005796 89.0
HKD1_k127_6254865_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000007055 76.0
HKD1_k127_6254865_8 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000000748 62.0
HKD1_k127_6324710_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.572e-252 785.0
HKD1_k127_6324710_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 614.0
HKD1_k127_6324710_10 Phosphodiester glycosidase - - - 0.000000000000000000000000005951 121.0
HKD1_k127_6324710_11 - - - - 0.000000007211 60.0
HKD1_k127_6324710_12 Multicopper oxidase - - - 0.00000001576 67.0
HKD1_k127_6324710_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 423.0
HKD1_k127_6324710_3 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 415.0
HKD1_k127_6324710_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 403.0
HKD1_k127_6324710_5 copper resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 395.0
HKD1_k127_6324710_6 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.000000000000000000000000000000000000000000000000000000001356 210.0
HKD1_k127_6324710_7 Cysteine-rich motif following a subset of SET domains K07117 - - 0.000000000000000000000000000000000000000000000002465 178.0
HKD1_k127_6324710_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000001266 170.0
HKD1_k127_6324710_9 - - - - 0.0000000000000000000000000000001374 126.0
HKD1_k127_6381630_0 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 5.154e-217 681.0
HKD1_k127_6381630_1 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 530.0
HKD1_k127_6381630_10 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000004587 79.0
HKD1_k127_6381630_11 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000001651 66.0
HKD1_k127_6381630_12 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000002778 52.0
HKD1_k127_6381630_2 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 373.0
HKD1_k127_6381630_3 Pseudouridine synthase K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 296.0
HKD1_k127_6381630_4 Glycosyl transferase family 2 K00721 GO:0000271,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0030258,GO:0030259,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000184 283.0
HKD1_k127_6381630_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002057 261.0
HKD1_k127_6381630_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000002786 160.0
HKD1_k127_6381630_7 Oxidoreductase family, C-terminal alpha/beta domain K18855 - 1.1.1.374 0.00000000000000000000000000000000000000479 158.0
HKD1_k127_6381630_8 Lipid A Biosynthesis N-terminal domain - - - 0.0000000000000000000000001686 110.0
HKD1_k127_6381630_9 - - - - 0.0000000000002158 74.0
HKD1_k127_640454_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1359.0
HKD1_k127_640454_1 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000001352 216.0
HKD1_k127_640454_2 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000000000005772 154.0
HKD1_k127_640454_3 - - - - 0.000000000000000000000000000000000001687 142.0
HKD1_k127_640454_4 - - - - 0.0007057 48.0
HKD1_k127_6435991_0 PFAM membrane bound O-acyl transferase MBOAT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 415.0
HKD1_k127_6435991_1 PFAM mannose-6-phosphate isomerase type I K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 334.0
HKD1_k127_6435991_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002521 283.0
HKD1_k127_6435991_3 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001147 269.0
HKD1_k127_6435991_4 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003416 246.0
HKD1_k127_6435991_5 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000000000000000000000000007016 161.0
HKD1_k127_6435991_7 - - - - 0.000000000000000000000003706 105.0
HKD1_k127_6435991_8 VanZ like family - - - 0.0000000000000000000182 97.0
HKD1_k127_6435991_9 - - - - 0.000000001916 66.0
HKD1_k127_6453973_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.068e-285 887.0
HKD1_k127_6453973_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.133e-282 885.0
HKD1_k127_6453973_10 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 386.0
HKD1_k127_6453973_11 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 344.0
HKD1_k127_6453973_12 Phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 337.0
HKD1_k127_6453973_13 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000001171 262.0
HKD1_k127_6453973_14 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000002632 249.0
HKD1_k127_6453973_15 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000779 228.0
HKD1_k127_6453973_16 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000004446 122.0
HKD1_k127_6453973_17 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000001716 117.0
HKD1_k127_6453973_18 glutamine-fructose-6-phosphate transaminase (isomerizing) activity - - - 0.0000000000000000000003573 98.0
HKD1_k127_6453973_19 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.000000000000000001319 87.0
HKD1_k127_6453973_2 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 611.0
HKD1_k127_6453973_20 cdp-diacylglycerol--glycerol-3-phosphate - - - 0.000000000000001003 80.0
HKD1_k127_6453973_21 ORF6N domain - - - 0.00000000000005628 76.0
HKD1_k127_6453973_3 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 503.0
HKD1_k127_6453973_4 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 504.0
HKD1_k127_6453973_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 469.0
HKD1_k127_6453973_6 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 463.0
HKD1_k127_6453973_7 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 451.0
HKD1_k127_6453973_8 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 441.0
HKD1_k127_6453973_9 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 425.0
HKD1_k127_6520014_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.123e-302 940.0
HKD1_k127_6520014_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.39e-233 731.0
HKD1_k127_6520014_10 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000002153 123.0
HKD1_k127_6520014_11 - - - - 0.00000000000000001452 90.0
HKD1_k127_6520014_2 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 430.0
HKD1_k127_6520014_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 427.0
HKD1_k127_6520014_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 421.0
HKD1_k127_6520014_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 291.0
HKD1_k127_6520014_6 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000001046 227.0
HKD1_k127_6520014_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000001888 211.0
HKD1_k127_6520014_8 - - - - 0.000000000000000000000000000000000000000004176 162.0
HKD1_k127_6520014_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000018 129.0
HKD1_k127_6522085_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 580.0
HKD1_k127_6522085_1 PFAM ABC transporter, transmembrane region K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 449.0
HKD1_k127_6522085_2 6-phosphogluconolactonase activity K20952 - - 0.00000000000003016 79.0
HKD1_k127_654961_0 Fumarylacetoacetase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 301.0
HKD1_k127_654961_1 histidyl-tRNA synthetase - - - 0.0000000000000000000000000000000000000000000000000000000002244 214.0
HKD1_k127_654961_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K00587 - 2.1.1.100 0.0000000000000000000000000000000000000002677 156.0
HKD1_k127_654961_3 Aldose 1-epimerase K01785 - 5.1.3.3 0.000000000000000005492 94.0
HKD1_k127_6563788_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.015e-254 810.0
HKD1_k127_6563788_1 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 329.0
HKD1_k127_6563788_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000005612 100.0
HKD1_k127_6563788_3 - - - - 0.000000000006101 72.0
HKD1_k127_6580940_0 Cupredoxin-like domain K00376 - 1.7.2.4 1.022e-315 976.0
HKD1_k127_6580940_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.111e-254 808.0
HKD1_k127_6580940_10 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000306 237.0
HKD1_k127_6580940_11 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000004932 238.0
HKD1_k127_6580940_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000001152 216.0
HKD1_k127_6580940_13 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000000000000000001631 196.0
HKD1_k127_6580940_14 Protein of unknown function (DUF1698) - - - 0.000000000000000000000000000000000000000000000001456 181.0
HKD1_k127_6580940_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000002417 168.0
HKD1_k127_6580940_16 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000004904 145.0
HKD1_k127_6580940_17 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000000002621 134.0
HKD1_k127_6580940_18 - K01992,K19341 - - 0.0000000000000000000000000000002677 133.0
HKD1_k127_6580940_19 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000001209 102.0
HKD1_k127_6580940_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 488.0
HKD1_k127_6580940_20 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000004003 79.0
HKD1_k127_6580940_22 PFAM Universal stress protein family - - - 0.000001741 53.0
HKD1_k127_6580940_3 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 385.0
HKD1_k127_6580940_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 382.0
HKD1_k127_6580940_5 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 342.0
HKD1_k127_6580940_6 COG0515 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009941 307.0
HKD1_k127_6580940_7 Crp Fnr family K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001978 274.0
HKD1_k127_6580940_8 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002191 259.0
HKD1_k127_6580940_9 NnrS protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000523 253.0
HKD1_k127_658508_0 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 400.0
HKD1_k127_658508_1 PFAM ATP-binding region ATPase domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 324.0
HKD1_k127_658508_2 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 325.0
HKD1_k127_658508_3 Two component transcriptional regulator, winged helix family K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 295.0
HKD1_k127_658508_6 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.0000000294 56.0
HKD1_k127_6616622_0 Bacterial protein of unknown function (DUF885) - - - 1.046e-209 663.0
HKD1_k127_6616622_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 503.0
HKD1_k127_6616622_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 462.0
HKD1_k127_6616622_3 - - - - 0.00000000000000000000007424 100.0
HKD1_k127_6616622_4 - - - - 0.0000001116 53.0
HKD1_k127_6806172_0 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 604.0
HKD1_k127_6806172_1 Alpha-amylase C-terminal beta-sheet domain K01176 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 572.0
HKD1_k127_6806172_10 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000000000000001673 219.0
HKD1_k127_6806172_11 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000001535 228.0
HKD1_k127_6806172_12 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000002576 201.0
HKD1_k127_6806172_13 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000002989 187.0
HKD1_k127_6806172_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000001512 176.0
HKD1_k127_6806172_15 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000004326 173.0
HKD1_k127_6806172_16 ChrR Cupin-like domain - - - 0.000000000000000000000000000000000000171 147.0
HKD1_k127_6806172_17 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000001724 144.0
HKD1_k127_6806172_18 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000001066 143.0
HKD1_k127_6806172_19 Cache domain - - - 0.00000000000000000000000000000000002251 149.0
HKD1_k127_6806172_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 550.0
HKD1_k127_6806172_20 NLI interacting factor-like phosphatase - - - 0.00000000000000000000000000000000005252 142.0
HKD1_k127_6806172_21 Glyoxalase - - - 0.00000000000000000000000000000002607 131.0
HKD1_k127_6806172_22 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000001589 128.0
HKD1_k127_6806172_23 - - - - 0.0000000000000000000000000000002126 129.0
HKD1_k127_6806172_25 HD domain - - - 0.000000000000000000000000001338 117.0
HKD1_k127_6806172_26 Phosphoglycerate mutase family - - - 0.000000000000000000000004078 108.0
HKD1_k127_6806172_27 SnoaL-like domain - - - 0.000000000000000000000009413 104.0
HKD1_k127_6806172_28 gluconolactonase activity - - - 0.0000000000000000002326 95.0
HKD1_k127_6806172_3 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 456.0
HKD1_k127_6806172_30 Domain of unknown function (DUF4440) - - - 0.000000000006092 72.0
HKD1_k127_6806172_31 - - - - 0.0000000003456 68.0
HKD1_k127_6806172_32 Protein of unknown function (DUF1697) - - - 0.000001192 57.0
HKD1_k127_6806172_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 413.0
HKD1_k127_6806172_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 382.0
HKD1_k127_6806172_6 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 316.0
HKD1_k127_6806172_8 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000011 238.0
HKD1_k127_6806172_9 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000004397 226.0
HKD1_k127_6942971_0 PFAM GlcNAc-PI de-N-acetylase - - - 2.83e-269 855.0
HKD1_k127_6942971_1 Sodium:solute symporter family - - - 3.28e-205 654.0
HKD1_k127_6942971_10 CAAX protease self-immunity - - - 0.000000000000000000000000000000001692 138.0
HKD1_k127_6942971_11 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000001644 126.0
HKD1_k127_6942971_12 Protein of unknown function (DUF423) - - - 0.000000000000000000000000001047 115.0
HKD1_k127_6942971_13 protein histidine kinase activity - - - 0.00000000000000000000000005882 114.0
HKD1_k127_6942971_14 CAAX protease self-immunity - - - 0.00000000000000000000009534 107.0
HKD1_k127_6942971_2 spermatogenesis - GO:0000003,GO:0007276,GO:0007283,GO:0008150,GO:0019953,GO:0022414,GO:0032501,GO:0032504,GO:0044703,GO:0048232,GO:0048609,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 479.0
HKD1_k127_6942971_3 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 419.0
HKD1_k127_6942971_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 394.0
HKD1_k127_6942971_5 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 367.0
HKD1_k127_6942971_6 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 349.0
HKD1_k127_6942971_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 315.0
HKD1_k127_6942971_8 RES - - - 0.0000000000000000000000000000000000005325 145.0
HKD1_k127_6942971_9 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000000000003975 135.0
HKD1_k127_6944891_0 Heat shock 70 kDa protein K04043 - - 0.0 1079.0
HKD1_k127_6944891_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.606e-287 888.0
HKD1_k127_6944891_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000001271 158.0
HKD1_k127_6944891_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000003921 153.0
HKD1_k127_6944891_12 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000009592 124.0
HKD1_k127_6944891_13 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000049 110.0
HKD1_k127_6944891_15 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000004188 89.0
HKD1_k127_6944891_16 Glutathione-dependent formaldehyde-activating - - - 0.00002358 49.0
HKD1_k127_6944891_17 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00073 44.0
HKD1_k127_6944891_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 9.726e-246 779.0
HKD1_k127_6944891_3 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 520.0
HKD1_k127_6944891_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 429.0
HKD1_k127_6944891_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 414.0
HKD1_k127_6944891_6 8-oxoguanine DNA glycosylase, N-terminal domain K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 355.0
HKD1_k127_6944891_7 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000001182 225.0
HKD1_k127_6944891_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000002205 208.0
HKD1_k127_6944891_9 DNA methylase - - - 0.0000000000000000000000000000000000000000000000000003387 190.0
HKD1_k127_69479_0 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 370.0
HKD1_k127_69479_1 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000000000000025 165.0
HKD1_k127_69479_2 - - - - 0.000000000000000000000000000000000000000001159 162.0
HKD1_k127_6955513_0 Nucleotidyl transferase K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 335.0
HKD1_k127_6955513_1 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 335.0
HKD1_k127_6963563_0 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 494.0
HKD1_k127_6963563_1 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000003372 254.0
HKD1_k127_6963563_2 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.0000000000000000000000000000000000000000000000000000000001591 211.0
HKD1_k127_6963563_3 HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000001916 209.0
HKD1_k127_6963563_4 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000001437 189.0
HKD1_k127_6963563_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000001987 162.0
HKD1_k127_6963563_6 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000003057 157.0
HKD1_k127_6963563_7 - - - - 0.00000000000000000000000000000000000001669 149.0
HKD1_k127_6963563_8 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000006019 100.0
HKD1_k127_7080165_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 3.528e-316 992.0
HKD1_k127_7080165_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.472e-288 920.0
HKD1_k127_7080165_10 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 387.0
HKD1_k127_7080165_11 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 331.0
HKD1_k127_7080165_12 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000001756 242.0
HKD1_k127_7080165_13 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.000000000000000000000000000000000000000000000000125 187.0
HKD1_k127_7080165_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000003663 156.0
HKD1_k127_7080165_15 - - - - 0.00000000000000000000000000000000000002654 149.0
HKD1_k127_7080165_16 - - - - 0.0000000000000000000000000000000000008618 146.0
HKD1_k127_7080165_17 - - - - 0.00000000000000000000002939 108.0
HKD1_k127_7080165_18 - - - - 0.0000000000000000000008331 105.0
HKD1_k127_7080165_19 - - - - 0.0000000002296 68.0
HKD1_k127_7080165_2 PFAM carbon starvation protein CstA K06200 - - 1.296e-261 822.0
HKD1_k127_7080165_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 541.0
HKD1_k127_7080165_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 520.0
HKD1_k127_7080165_5 Amino acid kinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 510.0
HKD1_k127_7080165_6 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009629 475.0
HKD1_k127_7080165_7 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 488.0
HKD1_k127_7080165_8 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 412.0
HKD1_k127_7080165_9 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 403.0
HKD1_k127_7083266_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 4.213e-203 641.0
HKD1_k127_7083266_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 314.0
HKD1_k127_7083266_2 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001399 267.0
HKD1_k127_7083266_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000004703 239.0
HKD1_k127_7083266_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000006467 205.0
HKD1_k127_7083266_5 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000000008299 207.0
HKD1_k127_7083266_6 Transposase - - - 0.00000000000000000000000000000000000000000000000001389 186.0
HKD1_k127_7084287_0 NADPH:quinone reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 368.0
HKD1_k127_7084287_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 367.0
HKD1_k127_7084287_2 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 314.0
HKD1_k127_7084287_3 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000002848 111.0
HKD1_k127_7117252_0 TRCF - - - 2.234e-297 945.0
HKD1_k127_7117252_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 539.0
HKD1_k127_7117252_2 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 445.0
HKD1_k127_7117252_3 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001683 229.0
HKD1_k127_7132796_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1244.0
HKD1_k127_7132796_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1106.0
HKD1_k127_7132796_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 482.0
HKD1_k127_7132796_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 364.0
HKD1_k127_7132796_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000001496 256.0
HKD1_k127_7132796_5 RF-1 domain - - - 0.000000000000000000000000000001147 127.0
HKD1_k127_7132796_6 Stf0 sulphotransferase K21014 - 2.8.2.37 0.000000000000000000000001797 113.0
HKD1_k127_7156898_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 9.532e-302 955.0
HKD1_k127_7156898_1 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 3.097e-285 889.0
HKD1_k127_7156898_10 Metal dependent phosphohydrolases with conserved 'HD' motif. K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 401.0
HKD1_k127_7156898_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 407.0
HKD1_k127_7156898_12 metalloendopeptidase activity K01392,K01414 - 3.4.24.15,3.4.24.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 409.0
HKD1_k127_7156898_13 radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 319.0
HKD1_k127_7156898_14 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 312.0
HKD1_k127_7156898_15 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 308.0
HKD1_k127_7156898_16 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002157 281.0
HKD1_k127_7156898_18 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000002874 240.0
HKD1_k127_7156898_19 HemY protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001271 248.0
HKD1_k127_7156898_2 Lipase maturation factor - - - 3.492e-222 698.0
HKD1_k127_7156898_20 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000003118 229.0
HKD1_k127_7156898_21 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004761 218.0
HKD1_k127_7156898_22 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.0000000000000000000000000000000000000000000000000000000000001127 222.0
HKD1_k127_7156898_23 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000002304 209.0
HKD1_k127_7156898_24 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000003528 225.0
HKD1_k127_7156898_25 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000001709 219.0
HKD1_k127_7156898_26 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000123 196.0
HKD1_k127_7156898_27 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000009066 190.0
HKD1_k127_7156898_28 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000000000008552 178.0
HKD1_k127_7156898_29 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000001996 176.0
HKD1_k127_7156898_3 Domain of unknown function (DUF3463) - - - 1.558e-214 674.0
HKD1_k127_7156898_30 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000000000000003275 174.0
HKD1_k127_7156898_31 Putative molybdenum carrier - - - 0.000000000000000000000000000000000002303 146.0
HKD1_k127_7156898_32 CHAD - - - 0.00000000000000000000000000000000006563 146.0
HKD1_k127_7156898_33 triphosphatase activity - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0050355 - 0.000000000000000000000000000000001215 135.0
HKD1_k127_7156898_34 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000003302 140.0
HKD1_k127_7156898_35 Cyclic phosphodiesterase-like - - - 0.00000000000000000000000003903 115.0
HKD1_k127_7156898_36 - - - - 0.0000000000000000000000006239 109.0
HKD1_k127_7156898_37 protein conserved in bacteria - - - 0.00000000000000000004149 92.0
HKD1_k127_7156898_39 - - - - 0.0000000000000000001944 90.0
HKD1_k127_7156898_4 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 1.958e-199 628.0
HKD1_k127_7156898_40 - - - - 0.00000000000000005309 83.0
HKD1_k127_7156898_41 - - - - 0.00000000008063 70.0
HKD1_k127_7156898_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 475.0
HKD1_k127_7156898_6 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 460.0
HKD1_k127_7156898_7 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 447.0
HKD1_k127_7156898_8 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 449.0
HKD1_k127_7156898_9 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 457.0
HKD1_k127_7158523_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 597.0
HKD1_k127_7158523_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 498.0
HKD1_k127_7158523_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 400.0
HKD1_k127_7158523_3 conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 288.0
HKD1_k127_7158523_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001147 291.0
HKD1_k127_7158523_5 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005988 268.0
HKD1_k127_7158523_6 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000003834 220.0
HKD1_k127_7168952_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.823e-231 727.0
HKD1_k127_7168952_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 3.418e-207 664.0
HKD1_k127_7168952_10 Alkaline phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 414.0
HKD1_k127_7168952_11 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 422.0
HKD1_k127_7168952_12 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 391.0
HKD1_k127_7168952_13 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 396.0
HKD1_k127_7168952_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 384.0
HKD1_k127_7168952_15 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000002395 243.0
HKD1_k127_7168952_16 - - - - 0.000000000000000000000000000000000000000000000001394 183.0
HKD1_k127_7168952_17 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000434 184.0
HKD1_k127_7168952_18 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000122 168.0
HKD1_k127_7168952_19 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.00000000000000000000000000005189 122.0
HKD1_k127_7168952_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 9.103e-205 644.0
HKD1_k127_7168952_20 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000005103 122.0
HKD1_k127_7168952_21 - - - - 0.00000000000002392 85.0
HKD1_k127_7168952_22 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000009469 71.0
HKD1_k127_7168952_23 Tetratricopeptide TPR_2 repeat protein - - - 0.00007702 57.0
HKD1_k127_7168952_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 4.496e-201 652.0
HKD1_k127_7168952_4 PFAM peptidase M29 aminopeptidase II K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 539.0
HKD1_k127_7168952_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 486.0
HKD1_k127_7168952_6 NADH dehydrogenase K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 461.0
HKD1_k127_7168952_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 473.0
HKD1_k127_7168952_8 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 456.0
HKD1_k127_7168952_9 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 441.0
HKD1_k127_7183701_0 AcrB/AcrD/AcrF family - - - 0.0 1374.0
HKD1_k127_7183701_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 492.0
HKD1_k127_7183701_2 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000001289 206.0
HKD1_k127_7183701_3 Protein of unknown function (DUF2892) - - - 0.0000000000000000009233 89.0
HKD1_k127_7183701_4 Xylose isomerase-like TIM barrel - - - 0.00000000000000002434 92.0
HKD1_k127_7183701_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K01406 - 3.4.24.40 0.0002383 48.0
HKD1_k127_7184381_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 4.692e-260 837.0
HKD1_k127_7184381_1 Pyruvate:ferredoxin oxidoreductase core domain II - - - 3.042e-250 788.0
HKD1_k127_7184381_10 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000002062 132.0
HKD1_k127_7184381_11 Protein of unknown function (DUF2723) - - - 0.000000000000000000000004653 111.0
HKD1_k127_7184381_12 CAAX protease self-immunity K07052 - - 0.0000000175 65.0
HKD1_k127_7184381_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 527.0
HKD1_k127_7184381_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 448.0
HKD1_k127_7184381_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 426.0
HKD1_k127_7184381_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 331.0
HKD1_k127_7184381_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 300.0
HKD1_k127_7184381_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007469 278.0
HKD1_k127_7184381_8 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000001272 250.0
HKD1_k127_7184381_9 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000001901 164.0
HKD1_k127_7223490_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000894 411.0
HKD1_k127_7223490_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 328.0
HKD1_k127_7223490_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 323.0
HKD1_k127_7223490_3 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 286.0
HKD1_k127_7223490_4 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000002454 227.0
HKD1_k127_7223490_5 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000000000000000000116 206.0
HKD1_k127_7223490_6 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000008018 159.0
HKD1_k127_7223490_7 transcriptional regulator K13771 - - 0.0000000000000000000000000000000003107 136.0
HKD1_k127_7223490_8 PFAM Hemolysin-type calcium-binding region - - - 0.000000000000000003291 94.0
HKD1_k127_7266772_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 1.4e-322 996.0
HKD1_k127_7266772_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 9.481e-242 760.0
HKD1_k127_7266772_10 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 347.0
HKD1_k127_7266772_11 Competence protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 368.0
HKD1_k127_7266772_12 DnaJ molecular chaperone homology domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 345.0
HKD1_k127_7266772_13 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 321.0
HKD1_k127_7266772_14 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 308.0
HKD1_k127_7266772_15 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001909 285.0
HKD1_k127_7266772_16 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006847 282.0
HKD1_k127_7266772_17 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000006053 246.0
HKD1_k127_7266772_18 PFAM Uracil-DNA glycosylase superfamily K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000002075 242.0
HKD1_k127_7266772_19 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000438 222.0
HKD1_k127_7266772_2 Belongs to the GPI family K01810 - 5.3.1.9 7.683e-204 656.0
HKD1_k127_7266772_20 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000135 216.0
HKD1_k127_7266772_21 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000406 213.0
HKD1_k127_7266772_22 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000009958 213.0
HKD1_k127_7266772_23 6-pyruvoyl tetrahydropterin synthase - - - 0.000000000000000000000000000000000000000000000000000000001077 202.0
HKD1_k127_7266772_24 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000008698 205.0
HKD1_k127_7266772_25 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000006411 199.0
HKD1_k127_7266772_26 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000152 164.0
HKD1_k127_7266772_27 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000127 165.0
HKD1_k127_7266772_28 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.00000000000000000000000000000000000000003239 162.0
HKD1_k127_7266772_29 phosphorelay sensor kinase activity K03406,K07675,K13598 - 2.7.13.3 0.000000000000000000000000000000000000763 151.0
HKD1_k127_7266772_3 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 615.0
HKD1_k127_7266772_30 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000003549 144.0
HKD1_k127_7266772_31 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000009426 112.0
HKD1_k127_7266772_32 AMP binding K06149 - - 0.0000000000000000000002056 104.0
HKD1_k127_7266772_34 Protein of unknown function (DUF2905) - - - 0.000000000000007102 77.0
HKD1_k127_7266772_35 ThiS family K03636 - - 0.000000000001521 71.0
HKD1_k127_7266772_36 Putative beta-barrel porin 2 K20920 - - 0.00000000001873 77.0
HKD1_k127_7266772_37 - - - - 0.00002439 51.0
HKD1_k127_7266772_38 - - - - 0.00002507 46.0
HKD1_k127_7266772_4 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 582.0
HKD1_k127_7266772_5 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 571.0
HKD1_k127_7266772_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 527.0
HKD1_k127_7266772_7 AAA ATPase central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 465.0
HKD1_k127_7266772_8 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 357.0
HKD1_k127_7266772_9 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 354.0
HKD1_k127_7284390_0 Anticodon binding domain K01880 - 6.1.1.14 1.499e-194 616.0
HKD1_k127_7284390_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000005517 265.0
HKD1_k127_7284390_2 OsmC-like protein - - - 0.0000000000000000000000004102 106.0
HKD1_k127_7284390_3 - - - - 0.00000000000008288 82.0
HKD1_k127_7398687_0 PFAM Polysulphide reductase NrfD K00185 - - 5.038e-216 679.0
HKD1_k127_7398687_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 618.0
HKD1_k127_7398687_2 COGs COG3278 Cbb3-type cytochrome oxidase subunit 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 482.0
HKD1_k127_7398687_3 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 365.0
HKD1_k127_7398687_4 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004059 257.0
HKD1_k127_7398687_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000005189 229.0
HKD1_k127_7398687_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000007053 177.0
HKD1_k127_7398687_7 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000003081 170.0
HKD1_k127_7398687_8 4Fe-4S dicluster domain - - - 0.0000004986 51.0
HKD1_k127_744429_0 Required for chromosome condensation and partitioning K03529 - - 5.302e-289 928.0
HKD1_k127_744429_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 3.535e-255 814.0
HKD1_k127_744429_10 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 362.0
HKD1_k127_744429_11 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 353.0
HKD1_k127_744429_12 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 332.0
HKD1_k127_744429_13 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000286 263.0
HKD1_k127_744429_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003315 258.0
HKD1_k127_744429_15 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000188 241.0
HKD1_k127_744429_16 gamma-glutamyl-gamma-aminobutyrate hydrolase activity K01658,K07010 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000001886 237.0
HKD1_k127_744429_17 Cupin superfamily (DUF985) - - - 0.00000000000000000000000000000000000000000000000000000000000000001794 226.0
HKD1_k127_744429_18 QueF-like protein K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000139 176.0
HKD1_k127_744429_2 Bacterial protein of unknown function (DUF885) - - - 3.148e-203 647.0
HKD1_k127_744429_20 Domain of unknown function (DUF4115) K15539 - - 0.00000003465 61.0
HKD1_k127_744429_22 Cupin superfamily (DUF985) K09705 - - 0.0002274 44.0
HKD1_k127_744429_3 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 597.0
HKD1_k127_744429_4 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 514.0
HKD1_k127_744429_5 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 499.0
HKD1_k127_744429_6 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 441.0
HKD1_k127_744429_7 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 413.0
HKD1_k127_744429_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 396.0
HKD1_k127_744429_9 transmembrane transporter activity K13021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 398.0
HKD1_k127_7444671_0 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 2.344e-236 747.0
HKD1_k127_7444671_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 548.0
HKD1_k127_7444671_10 - - - - 0.0000000000001834 76.0
HKD1_k127_7444671_11 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000002438 49.0
HKD1_k127_7444671_2 response regulator, receiver K07315,K20977 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 312.0
HKD1_k127_7444671_3 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000002794 248.0
HKD1_k127_7444671_4 belongs to the cytidylate kinase family. Type 1 subfamily K00800,K00945,K02945,K03527,K03977,K11753,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000002831 230.0
HKD1_k127_7444671_5 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000000000007686 159.0
HKD1_k127_7444671_6 mRNA catabolic process K06950,K09163 - - 0.0000000000000000000000000000000000003812 147.0
HKD1_k127_7444671_7 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000002202 124.0
HKD1_k127_7444671_8 Putative regulatory protein - - - 0.0000000000000000000000000000009519 126.0
HKD1_k127_7444671_9 DNA ligase N terminus K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000003089 94.0
HKD1_k127_7598163_0 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 459.0
HKD1_k127_7598163_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 350.0
HKD1_k127_7681550_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 372.0
HKD1_k127_7681550_1 FRG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002381 261.0
HKD1_k127_7681550_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000004081 162.0
HKD1_k127_7681550_3 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000003546 149.0
HKD1_k127_7681550_4 - - - - 0.00000000000000000000000000000000006458 143.0
HKD1_k127_7717246_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.511e-240 752.0
HKD1_k127_7717246_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 9.282e-206 656.0
HKD1_k127_7717246_10 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000000000002264 216.0
HKD1_k127_7717246_11 Ami_3 - - - 0.00000000000000000000000000000000000000000000000006085 185.0
HKD1_k127_7717246_12 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000002233 154.0
HKD1_k127_7717246_13 cellulase activity - - - 0.000000000000000000000000000000000000001062 161.0
HKD1_k127_7717246_14 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000004186 145.0
HKD1_k127_7717246_2 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 478.0
HKD1_k127_7717246_3 Sugar (and other) transporter K08178 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 445.0
HKD1_k127_7717246_4 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 433.0
HKD1_k127_7717246_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 401.0
HKD1_k127_7717246_6 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 347.0
HKD1_k127_7717246_7 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 346.0
HKD1_k127_7717246_8 Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005137 266.0
HKD1_k127_7717246_9 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005666 251.0
HKD1_k127_7732192_0 Alpha amylase catalytic K05343 - 3.2.1.1,5.4.99.16 1.536e-297 921.0
HKD1_k127_7732192_1 Secretory lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 420.0
HKD1_k127_7732192_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - 0.000000000000000000000000000000000000000000000000000005386 198.0
HKD1_k127_7732192_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000002686 183.0
HKD1_k127_7732192_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000004865 137.0
HKD1_k127_7732192_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000006734 115.0
HKD1_k127_7732192_7 KTSC domain - - - 0.00000000007094 67.0
HKD1_k127_7741424_0 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 545.0
HKD1_k127_7741424_1 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 360.0
HKD1_k127_7741424_2 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 340.0
HKD1_k127_7741424_3 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 295.0
HKD1_k127_7741424_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009978 264.0
HKD1_k127_7741424_5 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000008285 232.0
HKD1_k127_7741424_6 Chaperone of endosialidase - - - 0.000000000000000002433 98.0
HKD1_k127_7741424_7 Hep Hag repeat protein K07278,K21449 - - 0.0000000000005257 81.0
HKD1_k127_7877750_0 D-arabinono-1,4-lactone oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 468.0
HKD1_k127_7877750_1 Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 436.0
HKD1_k127_7877750_2 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 409.0
HKD1_k127_7877750_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 400.0
HKD1_k127_7877750_4 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 381.0
HKD1_k127_7877750_5 R3H domain - - - 0.00000000000000000000000000000000000000000000000000004125 192.0
HKD1_k127_7877750_6 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000002623 166.0
HKD1_k127_7877750_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000007349 109.0
HKD1_k127_7877750_8 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000227 81.0
HKD1_k127_789757_0 MmgE/PrpD family K01720 - 4.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 552.0
HKD1_k127_789757_1 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 526.0
HKD1_k127_789757_10 Protein of unknown function (DUF1203) - - - 0.000000000000000000001048 100.0
HKD1_k127_789757_11 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000001117 92.0
HKD1_k127_789757_12 tail collar domain protein K01406,K21449 - 3.4.24.40 0.0000000000000005238 85.0
HKD1_k127_789757_13 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000000005396 93.0
HKD1_k127_789757_14 - - - - 0.00000000001309 66.0
HKD1_k127_789757_15 Protein of unknown function (DUF3761) - - - 0.0000006412 57.0
HKD1_k127_789757_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 359.0
HKD1_k127_789757_3 methylisocitrate lyase activity K03417 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 351.0
HKD1_k127_789757_4 Sodium:dicarboxylate symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 342.0
HKD1_k127_789757_5 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 303.0
HKD1_k127_789757_6 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002137 231.0
HKD1_k127_789757_7 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000001112 203.0
HKD1_k127_789757_8 cellulase activity - - - 0.00000000000000000000000000000000000000000034 173.0
HKD1_k127_789757_9 HemY domain protein - - - 0.000000000000000000000000000000003805 150.0
HKD1_k127_8004211_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 2.218e-250 792.0
HKD1_k127_8004211_1 Alanine dehydrogenase/PNT, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 525.0
HKD1_k127_8004211_2 Uncharacterized ACR, COG1678 K07735 - - 0.000000000000000000000000000000000000000000000002214 180.0
HKD1_k127_8004211_4 Protein of unknown function (DUF4230) - - - 0.00000000000004372 81.0
HKD1_k127_8004211_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000009965 56.0
HKD1_k127_8019673_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1179.0
HKD1_k127_8019673_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.307e-271 854.0
HKD1_k127_8019673_10 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 469.0
HKD1_k127_8019673_11 Beta-Casp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 441.0
HKD1_k127_8019673_12 PFAM phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 374.0
HKD1_k127_8019673_13 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 342.0
HKD1_k127_8019673_14 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 335.0
HKD1_k127_8019673_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 310.0
HKD1_k127_8019673_16 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 300.0
HKD1_k127_8019673_17 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 300.0
HKD1_k127_8019673_18 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000231 262.0
HKD1_k127_8019673_19 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001879 254.0
HKD1_k127_8019673_2 Belongs to the glycosyl hydrolase 57 family K03406,K16149 - 2.4.1.18 7.487e-203 644.0
HKD1_k127_8019673_20 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000007349 226.0
HKD1_k127_8019673_21 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000004257 217.0
HKD1_k127_8019673_22 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000007222 166.0
HKD1_k127_8019673_23 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000006182 144.0
HKD1_k127_8019673_24 Transcriptional regulator, MarR K06075 - - 0.00000000000000000000000000000000001651 141.0
HKD1_k127_8019673_25 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000403 120.0
HKD1_k127_8019673_26 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000009103 117.0
HKD1_k127_8019673_28 Bacterial protein of unknown function (DUF883) - - - 0.00000000000001358 78.0
HKD1_k127_8019673_29 Psort location CytoplasmicMembrane, score - - - 0.0000000000003874 78.0
HKD1_k127_8019673_3 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 603.0
HKD1_k127_8019673_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 569.0
HKD1_k127_8019673_5 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 561.0
HKD1_k127_8019673_6 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 507.0
HKD1_k127_8019673_7 PFAM type II secretion system protein E - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 511.0
HKD1_k127_8019673_8 Nucleoside diphosphate kinase K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 495.0
HKD1_k127_8019673_9 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 467.0
HKD1_k127_845171_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 463.0
HKD1_k127_845171_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000752 224.0
HKD1_k127_845171_2 - - - - 0.0000000007689 67.0
HKD1_k127_845171_3 - - - - 0.000001756 53.0
HKD1_k127_855924_0 PFAM AMP-dependent synthetase and ligase K05939 - 2.3.1.40,6.2.1.20 5.257e-282 884.0
HKD1_k127_855924_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 404.0
HKD1_k127_855924_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 327.0
HKD1_k127_855924_3 Domain of unknown function (DUF697) - - - 0.000000000000000000000000000000000000000000000000002674 194.0
HKD1_k127_855924_4 YCII-related domain K09780 - - 0.00000000000000004417 84.0
HKD1_k127_855924_5 Cupin 2, conserved barrel domain protein - - - 0.00003569 48.0
HKD1_k127_882345_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 2.785e-285 885.0
HKD1_k127_882345_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 463.0
HKD1_k127_882345_2 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001768 252.0
HKD1_k127_882345_3 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000007608 223.0
HKD1_k127_882345_4 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.00000000000000000000000000007684 117.0
HKD1_k127_882345_5 Universal stress protein family - - - 0.0000000000000000003857 94.0
HKD1_k127_882372_0 PFAM Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000004632 233.0
HKD1_k127_882372_1 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000001616 143.0
HKD1_k127_882372_2 Universal stress protein - - - 0.0007497 46.0
HKD1_k127_97479_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 537.0
HKD1_k127_97479_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 509.0
HKD1_k127_97479_10 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate - - - 0.0000000000000000000000000000000000005642 146.0
HKD1_k127_97479_11 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000001696 107.0
HKD1_k127_97479_12 PFAM S23 ribosomal protein - - - 0.00000000000006612 76.0
HKD1_k127_97479_2 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 468.0
HKD1_k127_97479_3 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 451.0
HKD1_k127_97479_4 Transglutaminase-like superfamily K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 458.0
HKD1_k127_97479_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 428.0
HKD1_k127_97479_6 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 355.0
HKD1_k127_97479_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 324.0
HKD1_k127_97479_8 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000001601 210.0
HKD1_k127_97479_9 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000001101 206.0