Overview

ID MAG01754
Name HKD1_bin.74
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Competibacterales
Family Competibacteraceae
Genus CAIMUS01
Species
Assembly information
Completeness (%) 95.52
Contamination (%) 2.32
GC content (%) 57.0
N50 (bp) 10,916
Genome size (bp) 3,477,419

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3435

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1017316_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 4.928e-274 852.0
HKD1_k127_1017316_1 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 405.0
HKD1_k127_1017316_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 356.0
HKD1_k127_1017316_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000004219 212.0
HKD1_k127_1017316_4 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000001602 167.0
HKD1_k127_1017316_5 GYD domain - - - 0.0000000000000000000000000000001463 128.0
HKD1_k127_1017316_6 Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000000000000000007701 100.0
HKD1_k127_1017316_7 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000801 83.0
HKD1_k127_1017316_8 - - - - 0.0000000004605 66.0
HKD1_k127_105387_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.718e-218 694.0
HKD1_k127_105387_1 WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000678 617.0
HKD1_k127_105387_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 327.0
HKD1_k127_105387_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000001669 211.0
HKD1_k127_105387_4 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000000000000832 138.0
HKD1_k127_105387_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000002151 86.0
HKD1_k127_1067767_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 4.659e-305 951.0
HKD1_k127_1067767_1 Double sensory domain of two-component sensor kinase - - - 1.007e-257 827.0
HKD1_k127_1067767_10 S23 ribosomal protein - - - 0.00000000000000000000000008007 108.0
HKD1_k127_1067767_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.529e-232 734.0
HKD1_k127_1067767_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 386.0
HKD1_k127_1067767_4 PFAM ThiJ PfpI domain protein K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 313.0
HKD1_k127_1067767_5 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001549 274.0
HKD1_k127_1067767_6 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000001464 206.0
HKD1_k127_1067767_7 Thioesterase superfamily K19222 - 3.1.2.28 0.000000000000000000000000000000000000000000000000001626 185.0
HKD1_k127_1067767_8 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000004071 173.0
HKD1_k127_1067767_9 May be involved in recombination K03554 GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009295,GO:0019219,GO:0019222,GO:0031323,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363 - 0.00000000000000000000000001051 111.0
HKD1_k127_1076598_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1062.0
HKD1_k127_1076598_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 7.451e-254 805.0
HKD1_k127_1076598_10 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 367.0
HKD1_k127_1076598_11 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 361.0
HKD1_k127_1076598_12 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 361.0
HKD1_k127_1076598_13 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 336.0
HKD1_k127_1076598_14 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 336.0
HKD1_k127_1076598_15 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003954 261.0
HKD1_k127_1076598_16 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000000000002176 207.0
HKD1_k127_1076598_17 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000001203 198.0
HKD1_k127_1076598_18 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000303 189.0
HKD1_k127_1076598_19 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000000000000000000000000006932 166.0
HKD1_k127_1076598_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 505.0
HKD1_k127_1076598_20 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000002986 143.0
HKD1_k127_1076598_21 Domain of unknown function DUF29 - - - 0.00000000000000000000000000000000008231 140.0
HKD1_k127_1076598_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 457.0
HKD1_k127_1076598_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 427.0
HKD1_k127_1076598_5 zinc metalloprotease K11749 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 430.0
HKD1_k127_1076598_6 serine-type peptidase activity K04773,K21511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 402.0
HKD1_k127_1076598_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 398.0
HKD1_k127_1076598_8 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 374.0
HKD1_k127_1076598_9 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 364.0
HKD1_k127_1087002_0 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 567.0
HKD1_k127_1087002_1 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 520.0
HKD1_k127_1087002_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 398.0
HKD1_k127_1087002_3 response regulator - - - 0.00000000000000000000000000000000001256 138.0
HKD1_k127_1087002_4 response regulator receiver - - - 0.000000000000000000000000002636 124.0
HKD1_k127_1103301_0 UPF0313 protein - - - 0.0 1159.0
HKD1_k127_1103301_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 6.201e-303 941.0
HKD1_k127_1103301_10 Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 327.0
HKD1_k127_1103301_11 Pfam Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000504 276.0
HKD1_k127_1103301_12 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000002687 255.0
HKD1_k127_1103301_13 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000000000000374 166.0
HKD1_k127_1103301_14 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.0000000000000000000000000000000000000000004106 161.0
HKD1_k127_1103301_15 succinate dehydrogenase K00242 - - 0.000000000000000000000000000000000000001893 150.0
HKD1_k127_1103301_16 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000001463 132.0
HKD1_k127_1103301_17 - - - - 0.000000000000000000000000005975 116.0
HKD1_k127_1103301_18 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 0.00000000000000000004094 94.0
HKD1_k127_1103301_19 ORF located using Glimmer RBSfinder - - - 0.0000000000000000000441 94.0
HKD1_k127_1103301_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 8.149e-299 927.0
HKD1_k127_1103301_20 - - - - 0.000000000000000007597 86.0
HKD1_k127_1103301_21 Protein of unknown function (DUF1674) - - - 0.00000000001376 66.0
HKD1_k127_1103301_3 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 4.18e-271 843.0
HKD1_k127_1103301_4 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 1.532e-235 730.0
HKD1_k127_1103301_5 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 507.0
HKD1_k127_1103301_6 PFAM Thermolysin metallopeptidase, alpha-helical domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 492.0
HKD1_k127_1103301_7 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 381.0
HKD1_k127_1103301_8 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 366.0
HKD1_k127_1103301_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 344.0
HKD1_k127_1173545_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1741.0
HKD1_k127_1173545_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0 1020.0
HKD1_k127_1173545_2 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002234 273.0
HKD1_k127_1173545_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000524 168.0
HKD1_k127_1197511_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 582.0
HKD1_k127_1197511_1 Type III restriction enzyme, res subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 579.0
HKD1_k127_1197511_10 PFAM YcfA-like protein - - - 0.000000000000000000000000005668 110.0
HKD1_k127_1197511_11 deoxyhypusine monooxygenase activity K06921 - - 0.0000000000000000000000000547 114.0
HKD1_k127_1197511_12 Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase K07740 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.000000000000000000000001104 109.0
HKD1_k127_1197511_13 deoxyhypusine monooxygenase activity - - - 0.00000005323 65.0
HKD1_k127_1197511_2 Protein of unknown function (DUF790) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 471.0
HKD1_k127_1197511_3 DnaJ-class molecular chaperone K05516 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 411.0
HKD1_k127_1197511_4 PFAM Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000000000000000000000000000000000000000000006072 223.0
HKD1_k127_1197511_5 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000002476 208.0
HKD1_k127_1197511_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000008944 201.0
HKD1_k127_1197511_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000002336 185.0
HKD1_k127_1197511_8 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000001677 111.0
HKD1_k127_1197511_9 MerR HTH family regulatory protein K18997 - - 0.000000000000000000000000002168 114.0
HKD1_k127_1200195_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1734.0
HKD1_k127_1200195_1 Mandelate racemase muconate lactonizing enzyme K02549,K19802 - 4.2.1.113,5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 460.0
HKD1_k127_1200195_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 450.0
HKD1_k127_1200195_3 - - - - 0.0000000000385 71.0
HKD1_k127_1200195_4 Protein of unknown function (DUF433) - - - 0.00001897 49.0
HKD1_k127_1204766_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1098.0
HKD1_k127_1204766_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 600.0
HKD1_k127_1204766_10 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000002156 107.0
HKD1_k127_1204766_11 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000001616 78.0
HKD1_k127_1204766_12 NAD(P)H-binding - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000007684 73.0
HKD1_k127_1204766_13 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.0000004084 53.0
HKD1_k127_1204766_14 aspartyl protease K06985 - - 0.00001529 58.0
HKD1_k127_1204766_15 Tetratricopeptide repeat - - - 0.00003513 57.0
HKD1_k127_1204766_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 571.0
HKD1_k127_1204766_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 510.0
HKD1_k127_1204766_4 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 375.0
HKD1_k127_1204766_5 of the drug metabolite transporter (DMT) superfamily K15268 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 331.0
HKD1_k127_1204766_6 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000002703 254.0
HKD1_k127_1204766_7 Belongs to the RNase T2 family K01166 - 3.1.27.1 0.00000000000000000000000000000000000000000000000000005125 196.0
HKD1_k127_1204766_8 Protein of unknown function (DUF2505) - - - 0.000000000000000000000000000000000000002003 152.0
HKD1_k127_1204766_9 - - - - 0.00000000000000000000000000000739 120.0
HKD1_k127_1209078_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 8.131e-297 912.0
HKD1_k127_1209078_1 PFAM AMP-dependent synthetase and ligase K00666 - - 5.344e-273 848.0
HKD1_k127_1209078_2 Involved in the processing of the 5'end of 16S rRNA K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 608.0
HKD1_k127_1209078_3 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 468.0
HKD1_k127_1209078_4 Transposase and inactivated derivatives K07494 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004831 253.0
HKD1_k127_1209078_5 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000288 225.0
HKD1_k127_1209078_6 Hydrolase - - - 0.0000000000000000000000000000000001493 141.0
HKD1_k127_1209078_7 Transposase IS4 family - - - 0.00000000000000000007515 91.0
HKD1_k127_1212584_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 360.0
HKD1_k127_1212584_1 ATP synthase (C/AC39) subunit K02119 - - 0.000000000000000000000000000000000000000005705 161.0
HKD1_k127_1212584_2 - - - - 0.00000000000000000000000000000006966 128.0
HKD1_k127_1212584_3 - - - - 0.00000000000000000009906 93.0
HKD1_k127_1212584_4 - - - - 0.00000000000000001785 85.0
HKD1_k127_1246561_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1026.0
HKD1_k127_1246561_1 malic enzyme K00029 - 1.1.1.40 2.8e-322 1002.0
HKD1_k127_1246561_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.46e-271 840.0
HKD1_k127_1246561_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 445.0
HKD1_k127_1246561_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 327.0
HKD1_k127_1246561_5 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005155 234.0
HKD1_k127_1246561_6 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000000000003933 175.0
HKD1_k127_1251305_0 Aldehyde K07303 - 1.3.99.16 7.757e-243 766.0
HKD1_k127_1251305_1 transcription factor binding K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 532.0
HKD1_k127_1251305_2 Bacterial transglutaminase-like N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 424.0
HKD1_k127_1251305_3 PFAM Sulphatase-modifying factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 300.0
HKD1_k127_1251305_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001455 233.0
HKD1_k127_1251305_5 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000002507 210.0
HKD1_k127_1251305_6 Rhodanese Homology Domain - - - 0.0000000000000000000000000000004831 128.0
HKD1_k127_1251305_7 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000002009 126.0
HKD1_k127_1251305_8 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K15520 - 2.3.1.189 0.000000000000000000000005333 111.0
HKD1_k127_1257981_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 391.0
HKD1_k127_1257981_1 PFAM CBS domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 330.0
HKD1_k127_1257981_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000003593 172.0
HKD1_k127_1257981_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000002642 66.0
HKD1_k127_1273104_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 3.325e-210 662.0
HKD1_k127_1273104_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 9.169e-208 661.0
HKD1_k127_1273104_10 GAF domain K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000281 183.0
HKD1_k127_1273104_11 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000004579 105.0
HKD1_k127_1273104_12 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000001192 57.0
HKD1_k127_1273104_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 570.0
HKD1_k127_1273104_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 527.0
HKD1_k127_1273104_4 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 494.0
HKD1_k127_1273104_5 PFAM Surface antigen K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 486.0
HKD1_k127_1273104_6 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 447.0
HKD1_k127_1273104_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 414.0
HKD1_k127_1273104_8 Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003603 278.0
HKD1_k127_1273104_9 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006836 267.0
HKD1_k127_1278305_0 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 466.0
HKD1_k127_1278305_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001921 279.0
HKD1_k127_1278305_2 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000002143 237.0
HKD1_k127_1278305_3 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000006739 222.0
HKD1_k127_1278305_4 Hydrolase K20862 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0022611,GO:0032502,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104 0.00000000000000000000000000000000000000000000000000000000002421 214.0
HKD1_k127_1278305_5 - - - - 0.0000000000000008445 79.0
HKD1_k127_1278305_6 - - - - 0.00000002747 58.0
HKD1_k127_1278786_0 exonuclease recJ K07462 - - 3.692e-203 648.0
HKD1_k127_1278786_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 323.0
HKD1_k127_1278786_2 Diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000007381 120.0
HKD1_k127_1303659_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 2.521e-277 872.0
HKD1_k127_1303659_1 Glycosyl hydrolase family 57 - - - 2.366e-229 717.0
HKD1_k127_1303659_10 Trypsin-like peptidase domain - - - 0.0000000000000000000001808 108.0
HKD1_k127_1303659_11 Transcriptional regulator - - - 0.000000000000000008223 86.0
HKD1_k127_1303659_12 Glycosyl hydrolase family 57 - - - 0.000000000003539 69.0
HKD1_k127_1303659_13 belongs to the thioredoxin family K20444,K20543 - - 0.00000000001784 75.0
HKD1_k127_1303659_14 - - - - 0.0000000003237 61.0
HKD1_k127_1303659_15 Putative addiction module component - - - 0.00000002837 57.0
HKD1_k127_1303659_2 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 421.0
HKD1_k127_1303659_3 type I secretion outer membrane protein, TolC K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 360.0
HKD1_k127_1303659_4 Transcriptional regulator K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 301.0
HKD1_k127_1303659_5 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003821 261.0
HKD1_k127_1303659_6 belongs to the thioredoxin family K20444,K20543 - - 0.000000000000000000000000000000000000000000000000000002252 210.0
HKD1_k127_1303659_7 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000003835 156.0
HKD1_k127_1303659_8 Protein of unknown function (DUF2283) - - - 0.0000000000000000000000000000000004134 132.0
HKD1_k127_1303659_9 RES - - - 0.000000000000000000000000000000001691 136.0
HKD1_k127_1304991_0 OpgC protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 394.0
HKD1_k127_1304991_1 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000244 278.0
HKD1_k127_1304991_2 Transposase - - - 0.00000000000000001088 88.0
HKD1_k127_1304991_3 Protein of unknown function (DUF502) - - - 0.00000000003235 68.0
HKD1_k127_1305026_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 352.0
HKD1_k127_1305026_1 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000001488 221.0
HKD1_k127_1305026_2 - - - - 0.000000000002717 76.0
HKD1_k127_1331144_0 Cytochrome d1, heme K15864 - 1.7.2.1,1.7.99.1 1.579e-199 623.0
HKD1_k127_1331144_1 cytochrome d1, heme region K19345 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 556.0
HKD1_k127_1331144_2 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 353.0
HKD1_k127_1331144_3 transcriptional regulator AsnC family - - - 0.000000000000000000000000000000000000000000000000000000001269 203.0
HKD1_k127_1331144_4 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000003791 179.0
HKD1_k127_1331144_5 PFAM cytochrome c, class I K08738 - - 0.00000000000000000000000000000000009968 135.0
HKD1_k127_1331144_6 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.0000000000000000000000000000000001654 137.0
HKD1_k127_1344016_0 Starch synthase catalytic domain - - - 2.61e-201 641.0
HKD1_k127_1344016_1 PFAM ATP adenylyltransferase K00988 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 404.0
HKD1_k127_1344016_10 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - 0.0000000000002445 80.0
HKD1_k127_1344016_11 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.00000000000959 67.0
HKD1_k127_1344016_2 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000989 280.0
HKD1_k127_1344016_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004671 296.0
HKD1_k127_1344016_4 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000003147 241.0
HKD1_k127_1344016_5 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000001535 184.0
HKD1_k127_1344016_6 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000004162 141.0
HKD1_k127_1344016_7 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000001571 132.0
HKD1_k127_1344016_8 PFAM Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000000001698 128.0
HKD1_k127_1344016_9 positive regulation of growth K07746 - - 0.000000000000000000000000008302 113.0
HKD1_k127_1348334_0 Belongs to the group II decarboxylase family K01580 GO:0003674,GO:0003824,GO:0004351,GO:0006873,GO:0006885,GO:0008150,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019725,GO:0030003,GO:0030004,GO:0030641,GO:0042592,GO:0045852,GO:0048878,GO:0050801,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 4.1.1.15 2.324e-256 795.0
HKD1_k127_1348334_1 STAS domain - - - 0.0000000000000000000000000000000000000000000000009368 177.0
HKD1_k127_1348334_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000002806 153.0
HKD1_k127_1348334_3 Polyphosphate kinase 2 (PPK2) - - - 0.000003815 50.0
HKD1_k127_1348334_4 Domain of unknown function (DUF4160) - - - 0.00006046 46.0
HKD1_k127_1379316_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 511.0
HKD1_k127_1379316_1 Belongs to the agmatine deiminase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 440.0
HKD1_k127_1379316_10 May be involved in the biosynthesis of molybdopterin K03638,K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002561 273.0
HKD1_k127_1379316_11 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000551 271.0
HKD1_k127_1379316_12 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003424 266.0
HKD1_k127_1379316_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000003122 226.0
HKD1_k127_1379316_14 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000005425 216.0
HKD1_k127_1379316_15 PFAM Enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000009432 216.0
HKD1_k127_1379316_16 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000005273 191.0
HKD1_k127_1379316_17 PFAM toluene tolerance K07323 - - 0.0000000000000000000000000000000000000000000001615 175.0
HKD1_k127_1379316_18 General secretion pathway protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0000000000000000000000000000000000000000001808 168.0
HKD1_k127_1379316_19 - - - - 0.0000000000000000000000000000000000000001391 155.0
HKD1_k127_1379316_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 415.0
HKD1_k127_1379316_20 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000001415 161.0
HKD1_k127_1379316_21 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000003154 145.0
HKD1_k127_1379316_22 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000000000001802 138.0
HKD1_k127_1379316_23 PIN domain - - - 0.00000000000000000000000000001624 122.0
HKD1_k127_1379316_24 Nucleotidyltransferase domain K07075 - - 0.0000000000000000001504 94.0
HKD1_k127_1379316_25 Type II secretion system (T2SS), protein I K02458 - - 0.0000000000000000007644 92.0
HKD1_k127_1379316_26 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000001497 85.0
HKD1_k127_1379316_27 STAS domain K07122 - - 0.00000000000000002559 85.0
HKD1_k127_1379316_28 general secretion pathway protein K02457 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000001688 75.0
HKD1_k127_1379316_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 396.0
HKD1_k127_1379316_4 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 383.0
HKD1_k127_1379316_5 heat shock protein DnaJ K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 378.0
HKD1_k127_1379316_6 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 346.0
HKD1_k127_1379316_7 serine threonine protein kinase K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 349.0
HKD1_k127_1379316_8 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 302.0
HKD1_k127_1379316_9 ADP-glyceromanno-heptose 6-epimerase activity K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007179 280.0
HKD1_k127_1403576_0 endonuclease exonuclease phosphatase K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 404.0
HKD1_k127_1403576_1 reverse transcriptase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 366.0
HKD1_k127_1403576_2 NERD domain protein - - - 0.00000000000000000000000000000000000000000000001535 179.0
HKD1_k127_1403576_3 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000009888 123.0
HKD1_k127_1403576_4 - - - - 0.000000000000000000002203 106.0
HKD1_k127_1403576_5 PFAM Sulphatase-modifying factor - - - 0.00000000096 67.0
HKD1_k127_140368_0 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 - - 1.574e-267 828.0
HKD1_k127_140368_1 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 587.0
HKD1_k127_140368_10 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000000001788 139.0
HKD1_k127_140368_2 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 548.0
HKD1_k127_140368_3 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 374.0
HKD1_k127_140368_4 iron-sulfur cluster assembly K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 318.0
HKD1_k127_140368_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 282.0
HKD1_k127_140368_6 adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000001527 244.0
HKD1_k127_140368_7 SUF system FeS assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000000000000000000000002123 215.0
HKD1_k127_140368_8 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000004191 142.0
HKD1_k127_140368_9 other phosphorylase family 1 K01243 - 3.2.2.9 0.000000000000000000000000000000000009452 147.0
HKD1_k127_1419730_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 4.326e-219 696.0
HKD1_k127_1419730_2 type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000000000000000000000000000502 120.0
HKD1_k127_1419730_3 - - - - 0.00000000000000006333 83.0
HKD1_k127_1419730_4 PFAM aminotransferase, class I and II K14155 - 4.4.1.8 0.00000000001837 64.0
HKD1_k127_1444100_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 6.474e-297 923.0
HKD1_k127_1444100_1 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 488.0
HKD1_k127_1444100_2 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 426.0
HKD1_k127_1444100_3 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 398.0
HKD1_k127_1444100_4 PFAM Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000004125 235.0
HKD1_k127_1444100_5 Mut7-C RNAse domain - - - 0.00000000000000000000000000000000004575 140.0
HKD1_k127_1444100_6 Protein of unknown function (DUF433) - - - 0.000000000000000000000000000008528 120.0
HKD1_k127_1444100_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000000000000000003135 95.0
HKD1_k127_1455805_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 533.0
HKD1_k127_1455805_1 PFAM ErfK YbiS YcfS YnhG family protein K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 338.0
HKD1_k127_1455805_10 - - - - 0.00000000000000006242 89.0
HKD1_k127_1455805_11 Site-specific recombinases, DNA invertase Pin homologs K14060 - - 0.00000000000000251 80.0
HKD1_k127_1455805_12 - - - - 0.000000000000104 76.0
HKD1_k127_1455805_13 Transposase IS200 like - - - 0.000000000666 66.0
HKD1_k127_1455805_14 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000005936 57.0
HKD1_k127_1455805_15 sequence-specific DNA binding - - - 0.0005064 46.0
HKD1_k127_1455805_2 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 334.0
HKD1_k127_1455805_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 308.0
HKD1_k127_1455805_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000002503 205.0
HKD1_k127_1455805_5 epimerase - - - 0.0000000000000000000000000000000000000000000000000000009719 199.0
HKD1_k127_1455805_6 Zinc-binding dehydrogenase K13979 - - 0.000000000000000000000000000000000007988 139.0
HKD1_k127_1455805_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000001366 136.0
HKD1_k127_1455805_8 domain protein - - - 0.0000000000000000000000000000007633 124.0
HKD1_k127_1455805_9 LysE type translocator - - - 0.0000000000000000000000006241 112.0
HKD1_k127_1457615_0 Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003654 282.0
HKD1_k127_1457615_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004539 278.0
HKD1_k127_1457615_10 Thiol disulfide interchange protein K02199 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:0140096 - 0.0000000000000000000000003374 106.0
HKD1_k127_1457615_11 Phosphoribosyl transferase domain - - - 0.0000000000000001237 80.0
HKD1_k127_1457615_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001562 252.0
HKD1_k127_1457615_3 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000001523 233.0
HKD1_k127_1457615_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015232,GO:0015886,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019897,GO:0019898,GO:0022857,GO:0031224,GO:0031234,GO:0032991,GO:0042623,GO:0043190,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:1901678,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000002352 220.0
HKD1_k127_1457615_5 TIGRFAM Cytochrome c-type biogenesis protein CcmI K02200 - - 0.00000000000000000000000000000000000000000000000000000008337 211.0
HKD1_k127_1457615_6 COG0526 Thiol-disulfide isomerase and thioredoxins K03673 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000002235 180.0
HKD1_k127_1457615_7 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.00000000000000000000000000000000000000000007959 162.0
HKD1_k127_1457615_8 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000491 168.0
HKD1_k127_1457615_9 subunit of a heme lyase K02200,K04017 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.0000000000000000000000000000000000000838 150.0
HKD1_k127_1463273_0 PFAM Carbamoyltransferase K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 396.0
HKD1_k127_1463273_1 succinylglutamate desuccinylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 390.0
HKD1_k127_1463273_2 Desuccinylase aspartoacylase K06987 - - 0.000000000000000000000000000000000000000000000000000000000000004607 220.0
HKD1_k127_1463273_3 - - - - 0.000000000000000000000000000000267 126.0
HKD1_k127_1463273_4 - - - - 0.000000000000000000257 89.0
HKD1_k127_1463273_5 Phasin protein - - - 0.00000000000001883 80.0
HKD1_k127_147456_0 ABC transporter transmembrane region K06147 - - 1.014e-246 777.0
HKD1_k127_147456_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.69e-238 748.0
HKD1_k127_147456_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000003268 174.0
HKD1_k127_147456_11 Sterol-binding domain protein K03690 - - 0.0000000000000000000000000000000000000000006331 165.0
HKD1_k127_147456_12 Recombinase zinc beta ribbon domain - - - 0.00000000000000000000000000002178 127.0
HKD1_k127_147456_13 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00000000000000000001614 94.0
HKD1_k127_147456_14 lipolytic protein G-D-S-L family - - - 0.0000007393 61.0
HKD1_k127_147456_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.104e-211 665.0
HKD1_k127_147456_3 ATPase (AAA K07478 - - 1.422e-196 621.0
HKD1_k127_147456_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 378.0
HKD1_k127_147456_5 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 365.0
HKD1_k127_147456_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009223 279.0
HKD1_k127_147456_7 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004776 235.0
HKD1_k127_147456_8 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000001517 203.0
HKD1_k127_147456_9 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000001987 192.0
HKD1_k127_1538764_0 Adenylate and Guanylate cyclase catalytic domain - - - 3.092e-286 917.0
HKD1_k127_1538764_1 FAD linked oxidase K00104 - 1.1.3.15 1.819e-231 724.0
HKD1_k127_1538764_10 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000001393 141.0
HKD1_k127_1538764_11 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000001955 86.0
HKD1_k127_1538764_2 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 GO:0003674,GO:0003824,GO:0004793,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008732,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050179,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 469.0
HKD1_k127_1538764_3 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 453.0
HKD1_k127_1538764_4 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 472.0
HKD1_k127_1538764_5 TfuA-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 332.0
HKD1_k127_1538764_6 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001111 188.0
HKD1_k127_1538764_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000007151 177.0
HKD1_k127_1538764_8 membrane - - - 0.0000000000000000000000000000000000000000000006493 177.0
HKD1_k127_1538764_9 peptidase - - - 0.000000000000000000000000000000000000002213 151.0
HKD1_k127_1545368_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 3.01e-279 867.0
HKD1_k127_1545368_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.379e-244 767.0
HKD1_k127_1545368_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 346.0
HKD1_k127_1545368_11 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000396 194.0
HKD1_k127_1545368_12 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000000000000000000000000000000000001453 195.0
HKD1_k127_1545368_13 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000002018 180.0
HKD1_k127_1545368_14 electron transfer activity K02660 - - 0.0000000000000000004699 91.0
HKD1_k127_1545368_2 NADH:flavin oxidoreductase / NADH oxidase family - - - 1.741e-231 724.0
HKD1_k127_1545368_3 Capsular exopolysaccharide family K16554,K16692 - - 9.732e-209 673.0
HKD1_k127_1545368_4 Cytochrome c - - - 8.504e-198 629.0
HKD1_k127_1545368_5 COG2303 Choline dehydrogenase and related flavoproteins K03333 - 1.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 601.0
HKD1_k127_1545368_6 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 487.0
HKD1_k127_1545368_7 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 430.0
HKD1_k127_1545368_8 O-antigen ligase like membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 432.0
HKD1_k127_1545368_9 NmrA-like family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 417.0
HKD1_k127_1547338_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000003146 231.0
HKD1_k127_1551660_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 309.0
HKD1_k127_1551870_0 SMART HNH nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 585.0
HKD1_k127_1551870_1 crispr-associated protein K19076 - - 0.000000000000000000000000000000000000000000008112 171.0
HKD1_k127_1551870_2 ATPase involved in DNA repair - - - 0.00000000000000000000000000000000000915 143.0
HKD1_k127_1551870_3 SIR2-like domain - - - 0.00007543 51.0
HKD1_k127_1552054_0 Ketoacyl-synthetase C-terminal extension - - - 0.0 1768.0
HKD1_k127_1552054_1 filamentation induced by cAMP protein Fic - - - 1.262e-205 644.0
HKD1_k127_1552054_10 Methyltransferase domain - - - 0.000000000000000003521 96.0
HKD1_k127_1552054_11 Domain of unknown function (DUF4351) - - - 0.00000000000000001548 85.0
HKD1_k127_1552054_12 TIR domain - - - 0.0000008127 56.0
HKD1_k127_1552054_2 PIN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 354.0
HKD1_k127_1552054_3 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001729 275.0
HKD1_k127_1552054_4 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001224 273.0
HKD1_k127_1552054_5 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003732 273.0
HKD1_k127_1552054_6 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003034 269.0
HKD1_k127_1552054_7 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003369 267.0
HKD1_k127_1552054_8 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001628 268.0
HKD1_k127_1552054_9 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000927 247.0
HKD1_k127_1552606_0 AAA domain K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 463.0
HKD1_k127_1552606_1 - - - - 0.000000000000000000000000000001951 122.0
HKD1_k127_1552606_2 membrane K02451,K03832 - - 0.000000000000000000138 98.0
HKD1_k127_1552606_3 Transposase and inactivated derivatives K07494 - - 0.00000000000000002255 84.0
HKD1_k127_1552606_4 Homeodomain-like domain - - - 0.000000000000001992 79.0
HKD1_k127_1552606_5 PFAM IS1 transposase - - - 0.000000000003174 66.0
HKD1_k127_1552606_6 Transcriptional regulator - - - 0.0000000002389 66.0
HKD1_k127_1558706_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005889 247.0
HKD1_k127_1558706_1 Protein of unknown function (DUF4231) - - - 0.00000000000000000000000000000000000000676 157.0
HKD1_k127_1558706_2 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000001195 126.0
HKD1_k127_1558706_3 COG1024 Enoyl-CoA hydratase carnithine racemase K13766 - 4.2.1.18 0.000000000000001066 78.0
HKD1_k127_1561987_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 612.0
HKD1_k127_1561987_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 537.0
HKD1_k127_1561987_10 - - - - 0.000000000000000000000002013 107.0
HKD1_k127_1561987_11 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000008497 70.0
HKD1_k127_1561987_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 486.0
HKD1_k127_1561987_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 434.0
HKD1_k127_1561987_4 TIGRFAM ATP phosphoribosyltransferase, C-terminal domain K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 421.0
HKD1_k127_1561987_5 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 418.0
HKD1_k127_1561987_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 398.0
HKD1_k127_1561987_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 358.0
HKD1_k127_1561987_8 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 322.0
HKD1_k127_1561987_9 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000000000000168 212.0
HKD1_k127_1594164_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.313e-265 825.0
HKD1_k127_1594164_1 exporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 504.0
HKD1_k127_1594164_10 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.00000000000000000000000000000000000000008242 153.0
HKD1_k127_1594164_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000008565 158.0
HKD1_k127_1594164_12 dehydratase - - - 0.00000000000000000000000000000001105 131.0
HKD1_k127_1594164_13 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000007187 125.0
HKD1_k127_1594164_14 reverse transcriptase K00986 - 2.7.7.49 0.00003284 48.0
HKD1_k127_1594164_2 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 449.0
HKD1_k127_1594164_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 435.0
HKD1_k127_1594164_4 ATPase (AAA superfamily) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 391.0
HKD1_k127_1594164_5 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 354.0
HKD1_k127_1594164_6 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003412 247.0
HKD1_k127_1594164_7 Helix-turn-helix XRE-family like proteins K18831 - - 0.000000000000000000000000000000000000000000001462 168.0
HKD1_k127_1594164_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000002152 160.0
HKD1_k127_1594164_9 Gram-negative-bacterium-type cell wall biogenesis - - - 0.0000000000000000000000000000000000000000089 163.0
HKD1_k127_1610438_0 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 313.0
HKD1_k127_1610438_1 Belongs to the heat shock protein 70 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 293.0
HKD1_k127_1610438_10 GrpE K03687 - - 0.0000386 51.0
HKD1_k127_1610438_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000001549 241.0
HKD1_k127_1610438_3 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04068 - 1.97.1.4 0.00000000000000000000000000000000000000000000003355 175.0
HKD1_k127_1610438_4 type I restriction modification DNA specificity domain - - - 0.0000000000000000000000000000000000003098 145.0
HKD1_k127_1610438_5 PFAM Plasmid stabilisation system protein K06218 - - 0.000000000000000000000000000002724 121.0
HKD1_k127_1610438_6 Belongs to the heat shock protein 70 family - - - 0.000000000000000000000005373 108.0
HKD1_k127_1610438_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.000000000000000000000007231 111.0
HKD1_k127_1610438_8 toxin-antitoxin pair type II binding - - - 0.0000000001675 64.0
HKD1_k127_1610438_9 Belongs to the heat shock protein 70 family - - - 0.00000363 55.0
HKD1_k127_162013_0 oxidoreductase K14257 - 1.14.19.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 509.0
HKD1_k127_162013_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 324.0
HKD1_k127_162013_2 pteridine-dependent deoxygenase K18240 - 4.1.3.40,4.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000008519 252.0
HKD1_k127_162013_3 Methyltransferase domain - - - 0.0000000000000000000000000000001525 128.0
HKD1_k127_162013_4 pteridine-dependent deoxygenase K18240 - 4.1.3.40,4.1.3.45 0.0000000004356 64.0
HKD1_k127_1636715_0 aminotransferase class I and II K14261 - - 2.453e-219 685.0
HKD1_k127_1636715_1 homoserine dehydrogenase K00003 - 1.1.1.3 2.501e-197 622.0
HKD1_k127_1636715_2 COG0568 DNA-directed RNA polymerase, sigma subunit K03087 GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 392.0
HKD1_k127_1636715_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 383.0
HKD1_k127_1636715_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000005977 253.0
HKD1_k127_1636715_5 Smr protein - - - 0.0000000000000000000000000000000000000000000000000000002909 198.0
HKD1_k127_1636715_6 COG0739 Membrane proteins related to metalloendopeptidases K06194,K12943 GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944 - 0.0000000000000000000000000000000000003605 149.0
HKD1_k127_1636715_7 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000003226 135.0
HKD1_k127_1636715_8 Diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000001393 139.0
HKD1_k127_1637509_0 PFAM glycosyl transferase family 39 - - - 1.296e-228 730.0
HKD1_k127_1637509_1 PFAM Asparagine synthase K01953 - 6.3.5.4 2.114e-219 699.0
HKD1_k127_1637509_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 579.0
HKD1_k127_1637509_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 538.0
HKD1_k127_1637509_4 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 470.0
HKD1_k127_1637509_5 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 459.0
HKD1_k127_1637509_6 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001445 283.0
HKD1_k127_1637509_7 GtrA-like protein - - - 0.0000000000000000000000000000000000000001421 172.0
HKD1_k127_1637509_8 - - - - 0.000000000000000000000897 105.0
HKD1_k127_1637556_0 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 552.0
HKD1_k127_1637556_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 317.0
HKD1_k127_1637556_2 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 316.0
HKD1_k127_1637556_3 synthesis repressor, PhaR - - - 0.000000000000000000000000000000000000000000000000706 180.0
HKD1_k127_1644544_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 362.0
HKD1_k127_1644544_1 Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000007802 242.0
HKD1_k127_1644544_2 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.0000000000000000000000000000000000000000000000000009464 187.0
HKD1_k127_1652589_0 Molecular chaperone. Has ATPase activity K04079 - - 1.819e-294 914.0
HKD1_k127_1652589_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 475.0
HKD1_k127_1652589_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 409.0
HKD1_k127_1652589_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 400.0
HKD1_k127_1652589_4 TIGRFAM 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 323.0
HKD1_k127_1652589_5 - - - - 0.0000003045 59.0
HKD1_k127_1657612_0 ABC transporter K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 342.0
HKD1_k127_1657612_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 321.0
HKD1_k127_1657612_2 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002118 284.0
HKD1_k127_1657612_3 PFAM cytochrome B561 K12262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003372 273.0
HKD1_k127_1657612_4 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002373 249.0
HKD1_k127_1657612_5 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000009388 213.0
HKD1_k127_1657612_6 - - - - 0.000000000000000005976 90.0
HKD1_k127_1657612_7 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000006439 76.0
HKD1_k127_1657612_8 protein conserved in cyanobacteria - - - 0.000000007071 57.0
HKD1_k127_1657612_9 Transcriptional regulator - - - 0.00008879 48.0
HKD1_k127_1684246_0 Belongs to the heat shock protein 70 family - - - 0.0 1188.0
HKD1_k127_1684246_1 Belongs to the heat shock protein 70 family - - - 3.863e-292 907.0
HKD1_k127_1684246_2 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001902 258.0
HKD1_k127_1684246_3 Domain of unknown function (DUF2760) - - - 0.0000000000000000000000000000000000000000000000000000003206 198.0
HKD1_k127_1684246_4 PFAM ApaG domain protein K06195 - - 0.000000000000000000000000000000000000000000000000000008728 192.0
HKD1_k127_1684246_5 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 0.0000000000000000000000000000004147 124.0
HKD1_k127_1694787_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 422.0
HKD1_k127_1694787_1 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000002899 231.0
HKD1_k127_1694787_2 AAA domain K03496 - - 0.00000000000000000000000000000000000000000000000000001336 204.0
HKD1_k127_1694787_3 EamA-like transporter family - - - 0.000000000000000000000000000000005247 132.0
HKD1_k127_1694787_4 - - - - 0.0000000005866 63.0
HKD1_k127_1694787_5 Protein required for attachment to host cells - - - 0.0003547 46.0
HKD1_k127_1749527_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0 1361.0
HKD1_k127_1749527_1 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 362.0
HKD1_k127_1749527_2 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 317.0
HKD1_k127_1749527_3 TIGRFAM TIGR00268 family protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 287.0
HKD1_k127_1749527_4 4 iron, 4 sulfur cluster binding K02573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001302 275.0
HKD1_k127_1749527_5 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000002223 229.0
HKD1_k127_1749527_6 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000002281 213.0
HKD1_k127_1749527_7 TPR repeat - - - 0.000000000000000000000000000000000000000000000000008963 186.0
HKD1_k127_1749527_8 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000005839 145.0
HKD1_k127_1795050_0 Acyl-CoA synthetase (NDP forming) K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 557.0
HKD1_k127_1795050_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001205 271.0
HKD1_k127_1795050_2 - - - - 0.00000000000000000000000000000000000003902 156.0
HKD1_k127_1795050_3 phosphorelay signal transduction system - - - 0.0000000000000000000001078 102.0
HKD1_k127_1796260_0 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 327.0
HKD1_k127_1796260_1 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000008951 199.0
HKD1_k127_1796260_2 DNA mediated transformation K04096 - - 0.000000000000000000000000000000000000000000000000004922 191.0
HKD1_k127_1796260_3 IMG reference gene - - - 0.0000000000000000000000000000005077 123.0
HKD1_k127_1796260_4 Pfam:Methyltransf_26 - - - 0.000000000000000000000000000281 121.0
HKD1_k127_1812651_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 4.451e-247 786.0
HKD1_k127_1812651_1 Helicase K03722 - 3.6.4.12 2.205e-239 756.0
HKD1_k127_1812651_10 Surface antigen variable number K07278 - - 0.0000000000000000000000000000000000000000000000000000000008699 216.0
HKD1_k127_1812651_11 acetyltransferase K18815 - 2.3.1.82 0.000000000000000000000000000000000000000000000000003018 186.0
HKD1_k127_1812651_12 cell adhesion - - - 0.00000000000000000000000000000000000000000000553 175.0
HKD1_k127_1812651_13 - - - - 0.0000000000000000000007711 105.0
HKD1_k127_1812651_14 COG0729 Outer membrane protein K07278 - - 0.00000000000000000004888 95.0
HKD1_k127_1812651_15 Uncharacterized protein conserved in bacteria (DUF2058) K09912 - - 0.000000000000000004304 91.0
HKD1_k127_1812651_16 peptidyl-tyrosine sulfation - - - 0.0000000000008094 77.0
HKD1_k127_1812651_2 Fad linked oxidase K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 593.0
HKD1_k127_1812651_3 lysine 2,3-aminomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 574.0
HKD1_k127_1812651_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 566.0
HKD1_k127_1812651_5 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 498.0
HKD1_k127_1812651_6 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 397.0
HKD1_k127_1812651_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 362.0
HKD1_k127_1812651_8 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 315.0
HKD1_k127_1812651_9 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 310.0
HKD1_k127_1815136_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1383.0
HKD1_k127_1815136_1 Neisseria PilC beta-propeller domain K02674 - - 2.438e-252 825.0
HKD1_k127_1815136_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003438 235.0
HKD1_k127_1815136_11 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000007551 216.0
HKD1_k127_1815136_12 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000000001606 210.0
HKD1_k127_1815136_13 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000001623 183.0
HKD1_k127_1815136_14 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000001841 174.0
HKD1_k127_1815136_15 Type II transport protein GspH K08084 - - 0.00000000000000000000000000000000000000000006978 165.0
HKD1_k127_1815136_16 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000000000001251 155.0
HKD1_k127_1815136_17 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000000003706 121.0
HKD1_k127_1815136_18 type IV pilus modification protein PilV K02671 - - 0.00000000000000000000000009866 113.0
HKD1_k127_1815136_19 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.0000000000000000000001029 102.0
HKD1_k127_1815136_2 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 1.678e-248 779.0
HKD1_k127_1815136_20 Type IV pilus assembly protein PilX C-term K02673 - - 0.0000000001797 69.0
HKD1_k127_1815136_21 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0000009651 52.0
HKD1_k127_1815136_3 G-rich domain on putative tyrosine kinase K16692 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 634.0
HKD1_k127_1815136_4 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 593.0
HKD1_k127_1815136_5 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 496.0
HKD1_k127_1815136_6 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 476.0
HKD1_k127_1815136_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 466.0
HKD1_k127_1815136_8 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 348.0
HKD1_k127_1815136_9 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 304.0
HKD1_k127_1820752_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 455.0
HKD1_k127_1820752_1 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 404.0
HKD1_k127_1820752_2 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000002454 227.0
HKD1_k127_1820752_3 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000355 194.0
HKD1_k127_1820752_4 XamI restriction endonuclease - - - 0.00000000000000000000000000000000005762 136.0
HKD1_k127_1820752_5 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000000000001363 119.0
HKD1_k127_1820752_6 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000003129 113.0
HKD1_k127_1820752_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000003607 70.0
HKD1_k127_1846192_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 7.991e-211 677.0
HKD1_k127_1846192_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 2.18e-201 634.0
HKD1_k127_1846192_10 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000009973 132.0
HKD1_k127_1846192_11 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000001168 76.0
HKD1_k127_1846192_12 Glyoxalase-like domain K01759 - 4.4.1.5 0.00000008033 55.0
HKD1_k127_1846192_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 589.0
HKD1_k127_1846192_3 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 546.0
HKD1_k127_1846192_4 Sigma-54 interaction domain K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 551.0
HKD1_k127_1846192_5 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 429.0
HKD1_k127_1846192_6 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 361.0
HKD1_k127_1846192_7 carbohydrate binding K00702 - 2.4.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 323.0
HKD1_k127_1846192_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 289.0
HKD1_k127_1846192_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000009735 212.0
HKD1_k127_186432_0 PFAM Glycosyl hydrolases family 15 K07190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 395.0
HKD1_k127_186432_1 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.000000000000000000000000000000000000000000000000000000000000003073 226.0
HKD1_k127_186432_2 serine-type aminopeptidase activity K02030,K14475 - - 0.00000000000000000000001056 106.0
HKD1_k127_186432_3 Protein of unknown function (DUF2905) - - - 0.000000000000000000001316 95.0
HKD1_k127_1867446_0 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001292 246.0
HKD1_k127_1867446_1 NMT1-like family - - - 0.0000000000000000000000000000000000000000001631 177.0
HKD1_k127_1867446_2 - K07498 - - 0.000000000000000000000000000000000000000000238 162.0
HKD1_k127_1867446_3 PFAM Transposase - - - 0.0000000000000000000000000000000000000009568 151.0
HKD1_k127_1867446_4 - - - - 0.0000000002884 63.0
HKD1_k127_1869097_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 7.469e-237 740.0
HKD1_k127_1869097_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.047e-199 625.0
HKD1_k127_1869097_2 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 528.0
HKD1_k127_1869097_3 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006019 262.0
HKD1_k127_1869097_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000007282 128.0
HKD1_k127_1869097_5 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.000000000000000009525 85.0
HKD1_k127_1874902_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.661e-244 760.0
HKD1_k127_1874902_1 Polysaccharide biosynthesis protein - - - 1.218e-227 720.0
HKD1_k127_1874902_10 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 493.0
HKD1_k127_1874902_11 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 472.0
HKD1_k127_1874902_12 Zn-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 457.0
HKD1_k127_1874902_13 Kef-type K transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 455.0
HKD1_k127_1874902_14 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 423.0
HKD1_k127_1874902_15 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 421.0
HKD1_k127_1874902_16 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 405.0
HKD1_k127_1874902_17 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 358.0
HKD1_k127_1874902_18 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 353.0
HKD1_k127_1874902_19 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 351.0
HKD1_k127_1874902_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.148e-212 666.0
HKD1_k127_1874902_20 Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) K13007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 344.0
HKD1_k127_1874902_21 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 339.0
HKD1_k127_1874902_22 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 317.0
HKD1_k127_1874902_23 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 307.0
HKD1_k127_1874902_24 Baseplate J-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 308.0
HKD1_k127_1874902_25 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 296.0
HKD1_k127_1874902_26 Domain of unknown function DUF29 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002505 263.0
HKD1_k127_1874902_27 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004282 256.0
HKD1_k127_1874902_28 CHASE4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004739 257.0
HKD1_k127_1874902_29 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000001011 236.0
HKD1_k127_1874902_3 Heat shock 70 kDa protein K04043 - - 5.836e-205 643.0
HKD1_k127_1874902_30 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000000000000000001144 230.0
HKD1_k127_1874902_31 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000007299 212.0
HKD1_k127_1874902_32 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000003465 228.0
HKD1_k127_1874902_33 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000000000000000000000000000000000000007286 213.0
HKD1_k127_1874902_34 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 0.0000000000000000000000000000000000000000000000000009276 190.0
HKD1_k127_1874902_35 - - - - 0.0000000000000000000000000000000000000000000000000009366 203.0
HKD1_k127_1874902_36 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000000000000000000002363 160.0
HKD1_k127_1874902_37 - - - - 0.00000000000000000000000000000000000002125 162.0
HKD1_k127_1874902_39 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000006896 131.0
HKD1_k127_1874902_4 Modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 593.0
HKD1_k127_1874902_40 - - - - 0.0000000000000000000000000000002447 126.0
HKD1_k127_1874902_41 recombinase activity K06400 - - 0.000000000000000000000005633 107.0
HKD1_k127_1874902_42 - - - - 0.00000000000000000000001184 106.0
HKD1_k127_1874902_44 - - - - 0.0000000000000002526 86.0
HKD1_k127_1874902_46 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000002414 75.0
HKD1_k127_1874902_47 - - - - 0.0000000000001532 76.0
HKD1_k127_1874902_48 Protein of unknown function (DUF1289) K06938 - - 0.000000000003169 68.0
HKD1_k127_1874902_49 - - - - 0.000000000003708 74.0
HKD1_k127_1874902_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 564.0
HKD1_k127_1874902_50 - - - - 0.000000001123 62.0
HKD1_k127_1874902_51 - - - - 0.00000003289 55.0
HKD1_k127_1874902_53 - - - - 0.00000006874 60.0
HKD1_k127_1874902_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 555.0
HKD1_k127_1874902_7 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 560.0
HKD1_k127_1874902_8 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 523.0
HKD1_k127_1874902_9 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 511.0
HKD1_k127_1884343_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 7.926e-286 899.0
HKD1_k127_1884343_1 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 560.0
HKD1_k127_1884343_10 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000006524 66.0
HKD1_k127_1884343_11 Belongs to the bacterial solute-binding protein 3 family K09969 - - 0.000000003913 58.0
HKD1_k127_1884343_12 - - - - 0.0002488 47.0
HKD1_k127_1884343_2 unusual protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 469.0
HKD1_k127_1884343_3 WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 407.0
HKD1_k127_1884343_5 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 322.0
HKD1_k127_1884343_6 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 298.0
HKD1_k127_1884343_7 - - - - 0.0000000000000000000000000000137 125.0
HKD1_k127_1884343_8 Transport of potassium into the cell K03549 - - 0.0000000000000000000000168 108.0
HKD1_k127_1884343_9 multidrug transporter - - - 0.00000000000001334 80.0
HKD1_k127_1908271_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2203.0
HKD1_k127_1908271_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2198.0
HKD1_k127_1908271_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000000000000000000008832 123.0
HKD1_k127_1908271_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000001413 79.0
HKD1_k127_1908271_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 356.0
HKD1_k127_1908271_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 312.0
HKD1_k127_1908271_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 302.0
HKD1_k127_1908271_5 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003796 287.0
HKD1_k127_1908271_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001974 240.0
HKD1_k127_1908271_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000001215 234.0
HKD1_k127_1908271_8 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000001917 183.0
HKD1_k127_1908271_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000007408 168.0
HKD1_k127_1918896_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 551.0
HKD1_k127_1918896_1 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 307.0
HKD1_k127_1918896_2 lyase activity - - - 0.00000000000000000005004 92.0
HKD1_k127_1918896_3 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000126 82.0
HKD1_k127_1918896_4 PFAM IS1 transposase - - - 0.000000008543 56.0
HKD1_k127_1918896_5 Belongs to the N(4) N(6)-methyltransferase family K07316 - 2.1.1.72 0.000215 44.0
HKD1_k127_1928337_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 2.731e-277 880.0
HKD1_k127_1928337_1 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 511.0
HKD1_k127_1928337_10 Homeodomain-like domain - - - 0.0004488 47.0
HKD1_k127_1928337_2 response regulator receiver K13041 - - 0.000000000000000000000000000000000000000000000000000000000006626 215.0
HKD1_k127_1928337_3 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000002545 212.0
HKD1_k127_1928337_4 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000001696 194.0
HKD1_k127_1928337_5 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000006197 163.0
HKD1_k127_1928337_6 - - - - 0.000000000000000000000000000000105 134.0
HKD1_k127_1928337_7 - - - - 0.000000000002113 72.0
HKD1_k127_1928337_8 Protein of unknown function (DUF2934) - - - 0.0000001356 58.0
HKD1_k127_1928337_9 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 0.000408 43.0
HKD1_k127_1935517_0 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 518.0
HKD1_k127_1935517_1 permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 422.0
HKD1_k127_1935517_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 402.0
HKD1_k127_1935517_3 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 314.0
HKD1_k127_1935517_4 low molecular weight K03741,K03892 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000002685 247.0
HKD1_k127_1935517_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000025 203.0
HKD1_k127_1935517_6 transcriptional regulators K03892 - - 0.00000000000000000000000000002708 120.0
HKD1_k127_1935517_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000166 108.0
HKD1_k127_1935517_8 redox-active disulfide protein 2 - - - 0.000000000000000000001743 96.0
HKD1_k127_1943779_0 self proteolysis - - - 0.0000000000000000007636 101.0
HKD1_k127_1984038_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 8.16e-302 942.0
HKD1_k127_1984038_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 478.0
HKD1_k127_1984038_2 High frequency lysogenization protein HflD homolog K07153 - - 0.00000000000000000000000000000000000000000000000008005 185.0
HKD1_k127_1984038_3 Protein of unknown function (DUF2845) - - - 0.000000000000007473 80.0
HKD1_k127_1984038_4 Domain of unknown function (DUF4124) - - - 0.0005267 51.0
HKD1_k127_2005830_0 DEAD DEAH box helicase K06877 - - 0.0 1652.0
HKD1_k127_2005830_1 Type II restriction enzyme, methylase subunits - - - 1.637e-273 857.0
HKD1_k127_2005830_10 PFAM Transposase DDE domain - - - 0.0000000000000000006871 88.0
HKD1_k127_2005830_12 Domain of unknown function (DUF3368) - - - 0.0003617 44.0
HKD1_k127_2005830_2 DNA helicase - - - 1.777e-229 734.0
HKD1_k127_2005830_3 Dehydrogenase K00101,K00467 - 1.1.2.3,1.13.12.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 485.0
HKD1_k127_2005830_4 glycine betaine K02002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001429 280.0
HKD1_k127_2005830_5 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000005266 165.0
HKD1_k127_2005830_6 Uncharacterised protein family (UPF0175) - - - 0.000000000000000000000000000000001095 132.0
HKD1_k127_2005830_7 Type II secretory pathway component ExeA K02450 - - 0.0000000000000000000000000000002086 140.0
HKD1_k127_2005830_8 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000001879 113.0
HKD1_k127_2005830_9 Protein conserved in bacteria - - - 0.0000000000000000003123 94.0
HKD1_k127_2010316_0 MlaD protein K06192 - - 1.086e-206 657.0
HKD1_k127_2010316_1 Putative amidoligase enzyme (DUF2126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861 544.0
HKD1_k127_2010316_10 - - - - 0.00000000000000000004652 96.0
HKD1_k127_2010316_11 - - - - 0.0000000000000000304 81.0
HKD1_k127_2010316_12 Glycine-zipper domain - - - 0.0000000000000007364 80.0
HKD1_k127_2010316_13 Putative transposase, YhgA-like - - - 0.0000000000002044 79.0
HKD1_k127_2010316_14 Cysteine rich repeat - - - 0.000000000002462 69.0
HKD1_k127_2010316_15 Opacity family porin protein K03286 - - 0.0000000001381 62.0
HKD1_k127_2010316_2 PFAM Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 483.0
HKD1_k127_2010316_3 Short C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 303.0
HKD1_k127_2010316_4 Paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000000000000000000003064 243.0
HKD1_k127_2010316_5 Paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000000000000006314 219.0
HKD1_k127_2010316_6 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000000000000000000000000000000000000000000007351 222.0
HKD1_k127_2010316_7 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000002651 211.0
HKD1_k127_2010316_8 - - - - 0.0000000000000000000000000000001804 131.0
HKD1_k127_2010316_9 - - - - 0.00000000000000000000000000003941 122.0
HKD1_k127_2018468_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 572.0
HKD1_k127_2018468_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008862 512.0
HKD1_k127_2018468_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 449.0
HKD1_k127_2018468_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 387.0
HKD1_k127_2018468_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 359.0
HKD1_k127_2018468_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003668 246.0
HKD1_k127_2018468_6 COG0226 ABC-type phosphate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000001827 154.0
HKD1_k127_2018468_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000001027 66.0
HKD1_k127_2018468_9 - - - - 0.000000000888 60.0
HKD1_k127_2039769_0 Resolvase K06400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002234 284.0
HKD1_k127_2039769_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000004049 149.0
HKD1_k127_2039769_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000001238 117.0
HKD1_k127_2039769_3 Isochorismatase family - - - 0.00000000000000004601 81.0
HKD1_k127_2045398_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 3.838e-236 751.0
HKD1_k127_2045398_1 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000005881 166.0
HKD1_k127_2045398_2 TIR domain - - - 0.0000000000000000000503 104.0
HKD1_k127_2056461_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 582.0
HKD1_k127_2056461_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000002331 226.0
HKD1_k127_2056461_2 Belongs to the ompA family - - - 0.00000000000000000000000000000000000005476 150.0
HKD1_k127_2056461_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000005429 139.0
HKD1_k127_2057101_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 514.0
HKD1_k127_2057101_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 343.0
HKD1_k127_2057101_2 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0031403,GO:0031420,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0047954,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 288.0
HKD1_k127_2057101_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006084 277.0
HKD1_k127_2078842_0 SMART Chromosomal replication initiator DnaA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 417.0
HKD1_k127_2078842_1 protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008914 286.0
HKD1_k127_2078842_2 self proteolysis - - - 0.000000000000000002889 92.0
HKD1_k127_2091321_0 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 447.0
HKD1_k127_2091321_1 - - - - 0.000000000000000000000000000000000000000000003364 168.0
HKD1_k127_2091321_2 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.00000000000000000000000000000000000000000003161 172.0
HKD1_k127_2091321_3 Hydrogenase (NiFe) small subunit HydA K05927 - 1.12.5.1 0.0000478 49.0
HKD1_k127_2130726_0 SAM-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 520.0
HKD1_k127_2130726_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 426.0
HKD1_k127_2130726_10 phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.00000000000000000000000000000000000000001009 157.0
HKD1_k127_2130726_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000009924 91.0
HKD1_k127_2130726_12 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000009228 79.0
HKD1_k127_2130726_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705 - 0.00000000001082 68.0
HKD1_k127_2130726_2 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 417.0
HKD1_k127_2130726_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 387.0
HKD1_k127_2130726_4 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 343.0
HKD1_k127_2130726_5 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 328.0
HKD1_k127_2130726_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 302.0
HKD1_k127_2130726_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006882 274.0
HKD1_k127_2130726_8 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009453 250.0
HKD1_k127_2130726_9 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000001574 201.0
HKD1_k127_2132741_0 Conserved hypothetical protein 698 - - - 0.00000000000000000000000000000000000000000000000000000000000000007048 228.0
HKD1_k127_2132741_1 Belongs to the Dps family K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000007566 219.0
HKD1_k127_2132741_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000001451 214.0
HKD1_k127_2132741_3 PFAM IS1 transposase K07480 - - 0.000000000000000000000000000000000000001009 154.0
HKD1_k127_2132741_4 - - - - 0.0000000003377 67.0
HKD1_k127_2132741_5 Rhodanese Homology Domain - - - 0.0000002631 55.0
HKD1_k127_2168831_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1445.0
HKD1_k127_2168831_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1214.0
HKD1_k127_2168831_10 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000000000000002814 107.0
HKD1_k127_2168831_11 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.00002911 49.0
HKD1_k127_2168831_12 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0008175 45.0
HKD1_k127_2168831_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.681e-197 622.0
HKD1_k127_2168831_3 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 579.0
HKD1_k127_2168831_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 552.0
HKD1_k127_2168831_5 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 301.0
HKD1_k127_2168831_6 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000004651 197.0
HKD1_k127_2168831_7 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000004977 126.0
HKD1_k127_2168831_8 Regulatory protein RecX K03565 GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - 0.00000000000000000000000000006554 121.0
HKD1_k127_2168831_9 LigT like Phosphoesterase - - - 0.0000000000000000000000000001554 123.0
HKD1_k127_2177975_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843,K19810 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 396.0
HKD1_k127_2177975_1 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 351.0
HKD1_k127_2177975_2 PFAM EAL domain K21025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 349.0
HKD1_k127_2177975_3 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 319.0
HKD1_k127_2177975_4 Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 314.0
HKD1_k127_2177975_5 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000001896 66.0
HKD1_k127_2179108_0 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000009868 240.0
HKD1_k127_2179108_1 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000007192 150.0
HKD1_k127_2179108_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000003526 148.0
HKD1_k127_2179108_3 Helix-turn-helix domain - - - 0.00000000000000000000000002188 113.0
HKD1_k127_2179108_4 IS1 transposase - - - 0.00000000000000000000000004343 108.0
HKD1_k127_2179108_5 'glutamate synthase - - - 0.00000000000000000000002233 101.0
HKD1_k127_2179108_6 Protein of unknown function (DUF2283) - - - 0.000000000000000002529 88.0
HKD1_k127_2179108_7 'glutamate synthase - - - 0.00000003393 57.0
HKD1_k127_2184394_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1.036e-217 685.0
HKD1_k127_2184394_1 Permease YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006935 250.0
HKD1_k127_2184394_2 Permease YjgP YjgQ K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000001639 251.0
HKD1_k127_2184394_3 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000000000000000000000000000000000002675 147.0
HKD1_k127_2184394_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000003797 152.0
HKD1_k127_2184394_5 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000005995 102.0
HKD1_k127_2184394_6 Protein of unknown function (DUF3108) - - - 0.00000000000001526 77.0
HKD1_k127_2184394_7 Putative restriction endonuclease - - - 0.000000005492 60.0
HKD1_k127_2201785_0 tRNA synthetases class II (D, K and N) K09759 - 6.1.1.23 6.559e-237 739.0
HKD1_k127_2201785_1 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 437.0
HKD1_k127_2201785_10 PFAM PilT protein - - - 0.00000000000000000000000000000001307 130.0
HKD1_k127_2201785_11 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000004013 89.0
HKD1_k127_2201785_12 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000001842 76.0
HKD1_k127_2201785_2 Peptidase family S49 N-terminal K04774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 362.0
HKD1_k127_2201785_3 precorrin-3B C17-methyltransferase K05934,K13540,K13541 - 2.1.1.130,2.1.1.131,3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 339.0
HKD1_k127_2201785_4 PFAM cobalamin (vitamin B12) biosynthesis CbiX K03795 - 4.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 319.0
HKD1_k127_2201785_5 Cobalamin biosynthesis protein CbiG K02189 - 3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 306.0
HKD1_k127_2201785_6 Precorrin-8X methylmutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000284 246.0
HKD1_k127_2201785_7 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000007832 241.0
HKD1_k127_2201785_8 Precorrin-2 K03394 - 2.1.1.130,2.1.1.151 0.000000000000000000000000000000000000000000000000000000000000002779 229.0
HKD1_k127_2201785_9 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000002208 136.0
HKD1_k127_2203350_0 DNA invertase Pin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003918 280.0
HKD1_k127_2203350_1 COG2801 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001834 243.0
HKD1_k127_2209762_0 Protein of unknown function (DUF499) - - - 0.0 1026.0
HKD1_k127_2209762_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 582.0
HKD1_k127_2209762_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 536.0
HKD1_k127_2209762_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000000000000000000000000000000819 123.0
HKD1_k127_2209762_4 phospholipase C - - - 0.000000000000000000000000318 109.0
HKD1_k127_2209762_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000002148 106.0
HKD1_k127_2209762_6 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000002671 78.0
HKD1_k127_2209762_7 - - - - 0.00000000003458 67.0
HKD1_k127_2223682_0 Copper binding periplasmic protein CusF K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 509.0
HKD1_k127_2223682_1 COG1538 Outer membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001125 285.0
HKD1_k127_2228348_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1495.0
HKD1_k127_2228348_1 Proton-conducting membrane transporter K05568 - - 1.672e-215 678.0
HKD1_k127_2228348_2 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 458.0
HKD1_k127_2228348_3 Proton-conducting membrane transporter K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 428.0
HKD1_k127_2228348_4 transposase or invertase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006911 284.0
HKD1_k127_2228348_5 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000006068 232.0
HKD1_k127_2228348_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000979 139.0
HKD1_k127_2228348_7 Belongs to the TelA family - - - 0.000000000000000000000000000000003481 130.0
HKD1_k127_2228348_8 COG1278 Cold shock proteins K03704 - - 0.0000000000000000000000003091 107.0
HKD1_k127_2228348_9 SPFH domain-Band 7 family - - - 0.000000000146 62.0
HKD1_k127_2275031_0 Acetyl-CoA dehydrogenase C-terminal like K00249 - 1.3.8.7 1.122e-240 757.0
HKD1_k127_2275031_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 291.0
HKD1_k127_2275031_2 PFAM virulence factor family protein - - - 0.0000000000000000000000000000000000000000003564 162.0
HKD1_k127_2275031_3 COG2366 Protein related to penicillin acylase K01434,K07116 - 3.5.1.11,3.5.1.97 0.00000000002385 64.0
HKD1_k127_2275031_4 Penicillin acylase K01434 - 3.5.1.11 0.00003149 46.0
HKD1_k127_229543_0 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 588.0
HKD1_k127_229543_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 452.0
HKD1_k127_229543_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000002865 142.0
HKD1_k127_229543_3 lyase activity - - - 0.00000000000000000000007741 101.0
HKD1_k127_229543_4 - - - - 0.0000000000000000004558 89.0
HKD1_k127_229543_5 recombinase activity - - - 0.00001145 50.0
HKD1_k127_229543_6 ORF located using Glimmer RBSfinder - - - 0.00006465 48.0
HKD1_k127_2341139_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 5.774e-238 752.0
HKD1_k127_2341139_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 458.0
HKD1_k127_2341139_10 methyltransferase - - - 0.0006191 46.0
HKD1_k127_2341139_2 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002065 280.0
HKD1_k127_2341139_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000739 126.0
HKD1_k127_2341139_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000005153 105.0
HKD1_k127_2341139_5 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000003629 100.0
HKD1_k127_2341139_6 - - - - 0.0000000000000001035 86.0
HKD1_k127_2341139_7 mercury ion transmembrane transporter activity - - - 0.0000000000001963 76.0
HKD1_k127_2341139_8 Protein of unknown function (DUF5132) - - - 0.000000002779 62.0
HKD1_k127_2379438_0 Acyl-CoA dehydrogenase N terminal K20035 - - 3.942e-240 755.0
HKD1_k127_2379438_1 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 503.0
HKD1_k127_2379438_10 - - - - 0.0000926 49.0
HKD1_k127_2379438_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 478.0
HKD1_k127_2379438_3 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 434.0
HKD1_k127_2379438_4 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 298.0
HKD1_k127_2379438_5 Methyltransferase type 11 K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000033 276.0
HKD1_k127_2379438_6 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002069 237.0
HKD1_k127_2379438_7 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000000000003206 198.0
HKD1_k127_2379438_8 Mut7-C ubiquitin - - - 0.000000000000000000007392 95.0
HKD1_k127_2379438_9 - - - - 0.000007581 49.0
HKD1_k127_2407927_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.87e-213 672.0
HKD1_k127_2407927_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 486.0
HKD1_k127_2407927_2 Belongs to the P(II) protein family K04752 GO:0003674,GO:0005488,GO:0005515,GO:0006808,GO:0008150,GO:0042802,GO:0045848,GO:0048518,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000003855 191.0
HKD1_k127_2407927_3 Ammonium transporter K03320 - - 0.0000000000002763 70.0
HKD1_k127_2436346_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.561e-212 669.0
HKD1_k127_2436346_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 4.852e-197 622.0
HKD1_k127_2436346_10 DNA RNA helicase K03580 - - 0.000000000001965 71.0
HKD1_k127_2436346_11 ATPases associated with a variety of cellular activities K02049 - - 0.0000000001517 67.0
HKD1_k127_2436346_13 Protein of unknown function (DUF433) - - - 0.0002559 46.0
HKD1_k127_2436346_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 485.0
HKD1_k127_2436346_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 469.0
HKD1_k127_2436346_4 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 473.0
HKD1_k127_2436346_5 Domain of unknown function (DUF3482) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 440.0
HKD1_k127_2436346_6 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001832 274.0
HKD1_k127_2436346_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000001544 250.0
HKD1_k127_2436346_8 protein acetylation - - - 0.000000000000001787 83.0
HKD1_k127_2436346_9 Protein of unknown function (DUF721) - - - 0.0000000000001011 80.0
HKD1_k127_2492468_0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000312 244.0
HKD1_k127_2492468_1 Helicase conserved C-terminal domain - - - 0.00000000000000000000000000000000000003221 151.0
HKD1_k127_2492468_2 - - - - 0.00000000000000000000000000000001255 130.0
HKD1_k127_2492468_3 Transposase IS200 like K07491 - - 0.0000000000000000000000000000006083 125.0
HKD1_k127_2492468_5 - - - - 0.00000000000001457 74.0
HKD1_k127_2492468_6 Transposase IS200 like - - - 0.000000000001657 79.0
HKD1_k127_2492468_7 alpha beta - - - 0.000002366 53.0
HKD1_k127_2492468_8 COG1943 Transposase and inactivated derivatives K07491 - - 0.0003688 44.0
HKD1_k127_2494709_0 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 450.0
HKD1_k127_2494709_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 402.0
HKD1_k127_2494709_2 KR domain K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 316.0
HKD1_k127_2494709_3 Virulence factor BrkB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 309.0
HKD1_k127_2494709_4 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003808 289.0
HKD1_k127_2494709_5 SH3 domain K07184 - - 0.0000000000000000000000000000000000006058 149.0
HKD1_k127_2506403_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1190.0
HKD1_k127_2506403_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 9.599e-220 687.0
HKD1_k127_2506403_10 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:1901360,GO:1990817 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 293.0
HKD1_k127_2506403_11 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000006771 221.0
HKD1_k127_2506403_12 High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway K06203 - - 0.0000000000000000000000000000000000000000000000000000000000000439 228.0
HKD1_k127_2506403_13 Domain of unknown function DUF29 - - - 0.0000000000000000000000000000000000000000000009051 171.0
HKD1_k127_2506403_14 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000001184 132.0
HKD1_k127_2506403_15 - - - - 0.000000000000009395 75.0
HKD1_k127_2506403_16 - - - - 0.00000001106 59.0
HKD1_k127_2506403_17 - - - - 0.0000006188 53.0
HKD1_k127_2506403_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 533.0
HKD1_k127_2506403_3 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 460.0
HKD1_k127_2506403_4 Polysaccharide biosynthesis protein K03328 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 465.0
HKD1_k127_2506403_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 407.0
HKD1_k127_2506403_6 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 406.0
HKD1_k127_2506403_7 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 394.0
HKD1_k127_2506403_8 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 362.0
HKD1_k127_2506403_9 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 349.0
HKD1_k127_2514189_0 helix_turn_helix, Lux Regulon K03556 - - 2.914e-229 730.0
HKD1_k127_2514189_2 - - - - 0.00000000000000000000001596 102.0
HKD1_k127_252461_0 malic enzyme K00029 - 1.1.1.40 0.0 1016.0
HKD1_k127_252461_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 485.0
HKD1_k127_252461_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 402.0
HKD1_k127_252461_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 316.0
HKD1_k127_252461_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000001404 174.0
HKD1_k127_252461_5 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000006451 144.0
HKD1_k127_2555729_0 COG4166 ABC-type oligopeptide transport system, periplasmic component K13893 - - 1.948e-243 766.0
HKD1_k127_2555729_1 ABC-type dipeptide transport system periplasmic component K02035 - - 2.838e-209 666.0
HKD1_k127_2555729_2 ABC-type multidrug transport system ATPase and permease K06147 - - 5.869e-205 657.0
HKD1_k127_2555729_3 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 459.0
HKD1_k127_2555729_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 423.0
HKD1_k127_2555729_5 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 384.0
HKD1_k127_2555729_6 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 385.0
HKD1_k127_2555729_7 Host attachment protein - - - 0.00000000000000000000000000000000005032 138.0
HKD1_k127_2578238_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 589.0
HKD1_k127_2578238_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 557.0
HKD1_k127_2578238_10 XisH protein - - - 0.00000000000000000000000000000000000000000000000000004041 190.0
HKD1_k127_2578238_11 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 0.000000000000000000000000000000000000000000000000002732 193.0
HKD1_k127_2578238_12 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000003256 168.0
HKD1_k127_2578238_13 XisI protein - - - 0.0000000000000000000000000000000000000005346 152.0
HKD1_k127_2578238_14 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000000000001065 152.0
HKD1_k127_2578238_16 Transposase - - - 0.000000000006779 67.0
HKD1_k127_2578238_17 Helix-turn-helix domain - - - 0.0000001918 55.0
HKD1_k127_2578238_18 - - - - 0.000002943 53.0
HKD1_k127_2578238_19 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00001716 49.0
HKD1_k127_2578238_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 518.0
HKD1_k127_2578238_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 518.0
HKD1_k127_2578238_4 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 484.0
HKD1_k127_2578238_5 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 362.0
HKD1_k127_2578238_6 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 348.0
HKD1_k127_2578238_7 Inositol monophosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 332.0
HKD1_k127_2578238_8 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 319.0
HKD1_k127_2578238_9 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000000000848 241.0
HKD1_k127_2595842_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 613.0
HKD1_k127_2595842_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 503.0
HKD1_k127_2595842_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 473.0
HKD1_k127_2595842_3 cytochrome c peroxidase - - - 0.000961 52.0
HKD1_k127_2642218_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.52e-285 888.0
HKD1_k127_2642218_1 response regulator K07712 - - 2.409e-227 712.0
HKD1_k127_2642218_2 signal transduction histidine kinase K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 402.0
HKD1_k127_2642218_3 pfam nudix K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000009647 166.0
HKD1_k127_2642218_4 Aspartyl protease - - - 0.00000000000000000000000000000000000000335 150.0
HKD1_k127_2642218_5 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000002136 130.0
HKD1_k127_2667606_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 587.0
HKD1_k127_2667606_1 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 372.0
HKD1_k127_2667606_10 PFAM Rhodopirellula transposase - - - 0.00000002248 56.0
HKD1_k127_2667606_2 ATPases associated with a variety of cellular activities K02074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 331.0
HKD1_k127_2667606_3 PFAM periplasmic solute binding protein K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 321.0
HKD1_k127_2667606_4 Predicted permease K07089,K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 337.0
HKD1_k127_2667606_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 288.0
HKD1_k127_2667606_6 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000001163 236.0
HKD1_k127_2667606_7 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000002268 188.0
HKD1_k127_2667606_8 protein conserved in bacteria K09950 - - 0.000000000000000000000000000000000000000004956 163.0
HKD1_k127_2667606_9 zinc ion transport K00341,K02077,K09121,K09796 - 1.6.5.3,4.99.1.12 0.00000000000000000000000000001263 129.0
HKD1_k127_2675132_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1240.0
HKD1_k127_2675132_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000002958 200.0
HKD1_k127_2675132_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000006218 141.0
HKD1_k127_2740426_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 578.0
HKD1_k127_2740426_1 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 470.0
HKD1_k127_2740426_10 Cd(II) Pb(II)-responsive transcriptional regulator - - - 0.00000000000000255 79.0
HKD1_k127_2740426_11 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000004212 76.0
HKD1_k127_2740426_12 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.00000005577 54.0
HKD1_k127_2740426_13 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.000001612 50.0
HKD1_k127_2740426_14 - - - - 0.000003869 56.0
HKD1_k127_2740426_2 metabolite transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 379.0
HKD1_k127_2740426_3 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 313.0
HKD1_k127_2740426_4 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 290.0
HKD1_k127_2740426_5 reductase K05895 - 1.3.1.106,1.3.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000001232 261.0
HKD1_k127_2740426_6 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000001013 175.0
HKD1_k127_2740426_7 COG2867 Oligoketide cyclase lipid transport protein K18588 - - 0.0000000000000000000000000000000002256 137.0
HKD1_k127_2740426_8 IMG reference gene - - - 0.0000000000000000000002882 101.0
HKD1_k127_2742123_0 PFAM Transposase domain (DUF772) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 586.0
HKD1_k127_2742123_1 Putative cyclase - - - 0.00000000000006958 71.0
HKD1_k127_2756822_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 448.0
HKD1_k127_2756822_1 Squalene phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 418.0
HKD1_k127_2756822_2 Radical SAM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 402.0
HKD1_k127_2756822_3 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 409.0
HKD1_k127_2788237_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 421.0
HKD1_k127_2788237_1 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 320.0
HKD1_k127_2788237_2 Belongs to the UPF0250 family K09158 - - 0.000000000000000000006799 94.0
HKD1_k127_2788237_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000005159 84.0
HKD1_k127_2788237_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000002116 59.0
HKD1_k127_2788938_0 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 578.0
HKD1_k127_2788938_1 Belongs to the GARS family K01945,K13713 - 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 344.0
HKD1_k127_2788938_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000002613 171.0
HKD1_k127_2788938_3 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.000000000000000000000000000000000000000211 154.0
HKD1_k127_2788938_4 Belongs to the UPF0149 family K09895 - - 0.000000000000000000000000000000000007215 144.0
HKD1_k127_2788938_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - 0.000000000000000001179 89.0
HKD1_k127_2788938_6 TIGRFAM TIGR02449 family protein K09892 - - 0.0004293 46.0
HKD1_k127_2837916_0 Transport permease protein K01992,K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 396.0
HKD1_k127_2837916_1 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 379.0
HKD1_k127_2837916_2 ATP hydrolysis coupled proton transport - - - 0.0000000000000000000000000000000000000000005152 179.0
HKD1_k127_2837916_3 PFAM UbiA prenyltransferase - - - 0.00000000000000000000000000000000000000008781 151.0
HKD1_k127_2837916_4 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000001021 123.0
HKD1_k127_2837937_0 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 520.0
HKD1_k127_2837937_1 COG3209 Rhs family protein - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0004549,GO:0006139,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016078,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - 0.000000003826 71.0
HKD1_k127_2857874_0 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 7.911e-195 615.0
HKD1_k127_2857874_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 473.0
HKD1_k127_2857874_10 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001145 259.0
HKD1_k127_2857874_11 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000001958 250.0
HKD1_k127_2857874_12 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002748 246.0
HKD1_k127_2857874_13 Uncharacterized conserved protein (DUF2173) - - - 0.000000000000000000000000000000000000001053 151.0
HKD1_k127_2857874_14 Uncharacterized conserved protein (DUF2173) - - - 0.000000000000000000000000000000000000001981 150.0
HKD1_k127_2857874_15 sulfurtransferase activity - - - 0.0000000000000000000000000000000000005957 154.0
HKD1_k127_2857874_16 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000008132 138.0
HKD1_k127_2857874_17 Poly(hydroxyalcanoate) granule associated protein - - - 0.000000000000000000000000000003194 123.0
HKD1_k127_2857874_18 SnoaL-like domain - - - 0.0000000000000000000000000007125 117.0
HKD1_k127_2857874_19 Uncharacterized conserved protein (DUF2173) - - - 0.00000000000000000000000000116 116.0
HKD1_k127_2857874_2 Probable transposase K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 467.0
HKD1_k127_2857874_20 Transcriptional - - - 0.000000000000000000000000001442 114.0
HKD1_k127_2857874_21 acyl-coa-binding protein - - - 0.000000000000000000000000003378 113.0
HKD1_k127_2857874_22 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.0000000000000000000000002042 110.0
HKD1_k127_2857874_23 Protein of unknown function (DUF499) K06922 - - 0.0000000000000000000001394 99.0
HKD1_k127_2857874_24 RDD family - - - 0.0000000000000000000003424 104.0
HKD1_k127_2857874_25 NADP oxidoreductase coenzyme F420-dependent - - - 0.00000000000000000002215 93.0
HKD1_k127_2857874_26 transposase activity - - - 0.00000000003577 64.0
HKD1_k127_2857874_28 Tautomerase enzyme K01821 - 5.3.2.6 0.000000499 52.0
HKD1_k127_2857874_3 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 466.0
HKD1_k127_2857874_4 esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 447.0
HKD1_k127_2857874_5 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 363.0
HKD1_k127_2857874_6 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair K03424 GO:0000175,GO:0000302,GO:0000738,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009056,GO:0009057,GO:0009636,GO:0009987,GO:0010035,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046700,GO:0046872,GO:0050896,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 314.0
HKD1_k127_2857874_7 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 304.0
HKD1_k127_2857874_8 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001107 282.0
HKD1_k127_2857874_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002303 285.0
HKD1_k127_287502_0 Cation transporter/ATPase, N-terminus K01535 - 3.6.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 432.0
HKD1_k127_287502_1 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000003558 237.0
HKD1_k127_287502_2 HupE / UreJ protein - - - 0.000000000000000000000000000000001206 143.0
HKD1_k127_287502_3 Cation transporter/ATPase, N-terminus K01535 - 3.6.3.6 0.0000000000000000000000000000002212 129.0
HKD1_k127_287502_4 - - - - 0.000000000000000000000000002864 115.0
HKD1_k127_287502_5 Cation transporter/ATPase, N-terminus K01535 - 3.6.3.6 0.00000000000002093 77.0
HKD1_k127_287502_6 MarC family integral membrane protein K05595 - - 0.0005491 44.0
HKD1_k127_2934736_0 Cytochrome c - - - 0.0 1363.0
HKD1_k127_2934736_1 GMC oxidoreductase K00108 - 1.1.99.1 2.741e-319 986.0
HKD1_k127_2934736_2 COG2303 Choline dehydrogenase and related flavoproteins K03333 - 1.1.3.6 8.333e-260 810.0
HKD1_k127_2934736_3 electron transfer activity K02660 - - 1.092e-252 790.0
HKD1_k127_2934736_4 Esterase of the alpha-beta hydrolase superfamily - - - 1.084e-196 644.0
HKD1_k127_2934736_5 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002049 272.0
HKD1_k127_2934736_6 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000001206 129.0
HKD1_k127_2934736_7 VanZ like family - - - 0.0000000000000000001472 98.0
HKD1_k127_2936044_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.471e-281 878.0
HKD1_k127_2936044_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000003208 216.0
HKD1_k127_2936044_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000032 135.0
HKD1_k127_2936044_3 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000001168 76.0
HKD1_k127_2963752_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.24e-244 783.0
HKD1_k127_2963752_1 PFAM NAD-glutamate dehydrogenase K15371 - 1.4.1.2 2.233e-200 647.0
HKD1_k127_2963752_2 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 589.0
HKD1_k127_2963752_3 phosphoesterase RecJ domain protein K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 441.0
HKD1_k127_2963752_4 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000005287 140.0
HKD1_k127_2963752_5 - - - - 0.000000000000000000002944 97.0
HKD1_k127_2963752_6 COG3209 Rhs family protein - - - 0.000000000000000000006475 104.0
HKD1_k127_2963752_7 Nucleotidyltransferase domain - - - 0.00000000000001521 78.0
HKD1_k127_2963752_8 tail specific protease K03797 - 3.4.21.102 0.0001246 53.0
HKD1_k127_2963752_9 RES - - - 0.0005298 45.0
HKD1_k127_2965667_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000006976 139.0
HKD1_k127_2965667_1 long-chain fatty acid transport protein - - - 0.000000000000000000000000003823 119.0
HKD1_k127_2965667_2 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000001889 92.0
HKD1_k127_2965667_3 long-chain fatty acid transport protein - - - 0.000000002739 59.0
HKD1_k127_2965667_4 - - - - 0.0002626 45.0
HKD1_k127_2965667_5 Glycogen debranching enzyme - - - 0.0003133 43.0
HKD1_k127_2983643_0 COG0553 Superfamily II DNA RNA helicases, SNF2 family K03580 - - 2.747e-252 799.0
HKD1_k127_2983643_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.036e-235 738.0
HKD1_k127_2983643_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000001061 244.0
HKD1_k127_2983643_11 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000195 185.0
HKD1_k127_2983643_12 HAD-hyrolase-like - - - 0.00000000000000000000000000009869 125.0
HKD1_k127_2983643_13 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000006677 115.0
HKD1_k127_2983643_14 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000113 114.0
HKD1_k127_2983643_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 446.0
HKD1_k127_2983643_3 Sulfate tungstate uptake family ABC transporter, periplasmic substrate-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 388.0
HKD1_k127_2983643_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 378.0
HKD1_k127_2983643_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 349.0
HKD1_k127_2983643_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 329.0
HKD1_k127_2983643_7 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 302.0
HKD1_k127_2983643_8 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 291.0
HKD1_k127_2983643_9 ABC-type tungstate transport system, periplasmic component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000284 285.0
HKD1_k127_3005962_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 8.829e-311 964.0
HKD1_k127_3005962_1 PFAM AMP-dependent synthetase and ligase - - - 4.033e-234 737.0
HKD1_k127_3005962_10 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.00000000000000000000000000000000000000000000000000000000000000003449 231.0
HKD1_k127_3005962_11 Belongs to the HSP15 family K04762 - - 0.00000000000000000000000000000000001952 139.0
HKD1_k127_3005962_12 NlpC/P60 family - - - 0.0000000000000000000000000000000002968 139.0
HKD1_k127_3005962_13 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000003394 126.0
HKD1_k127_3005962_14 RNA-binding protein - - - 0.000000000000000000000000000004853 121.0
HKD1_k127_3005962_15 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000000000000487 103.0
HKD1_k127_3005962_16 Phosphopantetheine attachment site - - - 0.000000000000000000000006282 102.0
HKD1_k127_3005962_17 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000000008823 96.0
HKD1_k127_3005962_18 - - - - 0.00000000000000000005793 97.0
HKD1_k127_3005962_19 ProQ/FINO family - - - 0.00000000000001706 79.0
HKD1_k127_3005962_2 PFAM Orn DAP Arg decarboxylase 2 K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 608.0
HKD1_k127_3005962_3 Belongs to the ParA family K03609 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0007059,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051782,GO:0060187,GO:0065007,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 422.0
HKD1_k127_3005962_4 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 396.0
HKD1_k127_3005962_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 362.0
HKD1_k127_3005962_6 TIGRFAM Hydrolase, ortholog 1, exosortase system type 1 associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 343.0
HKD1_k127_3005962_7 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 316.0
HKD1_k127_3005962_8 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 303.0
HKD1_k127_3005962_9 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 275.0
HKD1_k127_3012477_0 glycogen (starch) synthase activity K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 581.0
HKD1_k127_3012477_1 Pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 565.0
HKD1_k127_3012477_2 Starch synthase catalytic domain K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 520.0
HKD1_k127_3012477_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 324.0
HKD1_k127_3012477_4 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 318.0
HKD1_k127_3012477_5 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004821 246.0
HKD1_k127_3012477_6 phosphoenolpyruvate-dependent sugar phosphotransferase system K05881 - 2.7.1.121 0.00000000000000000000000000000000000000000000000000000000000000000000005367 261.0
HKD1_k127_3012477_7 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000926 214.0
HKD1_k127_3012477_8 Putative restriction endonuclease - - - 0.000000000000000000001594 101.0
HKD1_k127_3012477_9 DnaJ molecular chaperone homology domain - - - 0.00000000000000000002986 95.0
HKD1_k127_304827_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 526.0
HKD1_k127_304827_1 Uncharacterized protein conserved in bacteria (DUF2272) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 306.0
HKD1_k127_304827_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000004867 249.0
HKD1_k127_304827_3 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000002863 93.0
HKD1_k127_304827_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000008867 78.0
HKD1_k127_304827_5 Hydrogenase maturation protease - - - 0.000006057 49.0
HKD1_k127_304827_6 CHAT domain - - - 0.00003438 51.0
HKD1_k127_304827_7 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0005401 43.0
HKD1_k127_3070065_0 Putative transposase, YhgA-like - - - 0.000000000000000000000000000000000000000000000000000000000000000009505 237.0
HKD1_k127_3070065_1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000008013 121.0
HKD1_k127_3070065_3 Protein of unknown function (DUF433) - - - 0.000000000000002083 79.0
HKD1_k127_3070065_4 - - - - 0.0000000000000642 82.0
HKD1_k127_3079585_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 6.964e-239 746.0
HKD1_k127_3079585_1 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 520.0
HKD1_k127_3079585_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 415.0
HKD1_k127_3079585_3 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 349.0
HKD1_k127_3079585_4 Amino acid polyamine organocation transporter, APC superfamily K03294 - - 0.000000000000000000000000003104 114.0
HKD1_k127_3079585_5 EamA-like transporter family - - - 0.000000000001429 68.0
HKD1_k127_3101448_0 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 618.0
HKD1_k127_3101448_1 TIGRFAM death-on-curing family protein K07341 - - 0.00000000000000000000000000000000000000000000001925 174.0
HKD1_k127_3101448_10 COG3335 Transposase and inactivated derivatives - - - 0.000000001843 59.0
HKD1_k127_3101448_11 IMG reference gene - - - 0.000001268 55.0
HKD1_k127_3101448_13 IMG reference gene - - - 0.0001157 47.0
HKD1_k127_3101448_2 - K07498 - - 0.000000000000000000000000000000000000000000238 161.0
HKD1_k127_3101448_3 HNH nucleases - - - 0.0000000000000000000000000000000000000001173 155.0
HKD1_k127_3101448_4 HsdM N-terminal domain K03427 - 2.1.1.72 0.000000000000000000000000000000000002963 140.0
HKD1_k127_3101448_5 COG3335 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000009088 135.0
HKD1_k127_3101448_6 SpoVT / AbrB like domain - - - 0.0000000000000000000000000000003197 123.0
HKD1_k127_3101448_7 COG0286 Type I restriction-modification system methyltransferase subunit K03427 - 2.1.1.72 0.000000000000000001184 86.0
HKD1_k127_3101448_8 PFAM Transposase - - - 0.0000000000000001119 80.0
HKD1_k127_3101448_9 COG3335 Transposase and inactivated derivatives - - - 0.00000000000009586 71.0
HKD1_k127_3110840_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01907 - 6.2.1.16 2.16e-306 949.0
HKD1_k127_3110840_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 475.0
HKD1_k127_3110840_2 PFAM Short-chain dehydrogenase reductase SDR K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 347.0
HKD1_k127_3110840_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K11151,K15734 GO:0000122,GO:0000988,GO:0000989,GO:0001076,GO:0001191,GO:0001523,GO:0003674,GO:0003824,GO:0004745,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005789,GO:0005811,GO:0006066,GO:0006081,GO:0006355,GO:0006357,GO:0006629,GO:0006720,GO:0006721,GO:0006950,GO:0008134,GO:0008150,GO:0008152,GO:0008283,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010604,GO:0010605,GO:0010629,GO:0010638,GO:0010639,GO:0010817,GO:0012505,GO:0016020,GO:0016101,GO:0016491,GO:0016614,GO:0016616,GO:0017053,GO:0019219,GO:0019222,GO:0031056,GO:0031057,GO:0031058,GO:0031063,GO:0031065,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031399,GO:0031400,GO:0031401,GO:0031984,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032991,GO:0033043,GO:0033044,GO:0033555,GO:0033613,GO:0034308,GO:0034754,GO:0035065,GO:0035067,GO:0042175,GO:0042445,GO:0042572,GO:0042574,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043616,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045892,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050673,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051253,GO:0055114,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090311,GO:0090312,GO:0098827,GO:0140110,GO:1901615,GO:1901983,GO:1901984,GO:1902275,GO:1902679,GO:1903506,GO:1903507,GO:1905268,GO:1905269,GO:2000112,GO:2000113,GO:2000756,GO:2000757,GO:2001141,GO:2001251,GO:2001252 1.1.1.105 0.000000000000000000000000000000000000000000000000000001193 199.0
HKD1_k127_3128192_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.00000000000000000000000000000000000001082 153.0
HKD1_k127_3128192_2 lipid catabolic process - - - 0.0000000000000000000000000001965 124.0
HKD1_k127_3128192_3 - - - - 0.000000000000000000000000001893 114.0
HKD1_k127_3128192_4 PFAM YcfA-like protein - - - 0.000000000000000000000007073 101.0
HKD1_k127_3128192_5 Alpha amylase catalytic - - - 0.000000000000002388 77.0
HKD1_k127_3128192_6 Transposase - - - 0.000000000009681 74.0
HKD1_k127_3176897_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 6.317e-310 977.0
HKD1_k127_3176897_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 528.0
HKD1_k127_3176897_10 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000002799 194.0
HKD1_k127_3176897_11 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000009065 181.0
HKD1_k127_3176897_12 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000007345 154.0
HKD1_k127_3176897_13 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000000000001868 160.0
HKD1_k127_3176897_14 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000004056 139.0
HKD1_k127_3176897_15 - - - - 0.000000000000000000000000006683 117.0
HKD1_k127_3176897_16 protein conserved in bacteria - - - 0.00000000000000000000000005013 116.0
HKD1_k127_3176897_17 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000004197 110.0
HKD1_k127_3176897_18 Zinc-finger domain - - - 0.0000000000000000000003987 100.0
HKD1_k127_3176897_19 transposase, IS891 IS1136 IS1341 family K07496 - - 0.00000004992 58.0
HKD1_k127_3176897_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 513.0
HKD1_k127_3176897_20 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000001996 61.0
HKD1_k127_3176897_3 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 494.0
HKD1_k127_3176897_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 494.0
HKD1_k127_3176897_5 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 472.0
HKD1_k127_3176897_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 456.0
HKD1_k127_3176897_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 286.0
HKD1_k127_3176897_8 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005972 258.0
HKD1_k127_3176897_9 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000000000000000000261 212.0
HKD1_k127_3177945_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 6.68e-240 757.0
HKD1_k127_3177945_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004935 279.0
HKD1_k127_3177945_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000005339 162.0
HKD1_k127_3182564_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 529.0
HKD1_k127_3182564_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 499.0
HKD1_k127_3182564_10 - - - - 0.0000000000000000002503 92.0
HKD1_k127_3182564_11 FimV C-terminal K08086 - - 0.000000000002951 72.0
HKD1_k127_3182564_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 494.0
HKD1_k127_3182564_3 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 369.0
HKD1_k127_3182564_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 344.0
HKD1_k127_3182564_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000006834 248.0
HKD1_k127_3182564_6 Competence protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004519 246.0
HKD1_k127_3182564_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000002668 195.0
HKD1_k127_3182564_8 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000001458 182.0
HKD1_k127_3182564_9 - - - - 0.0000000000000000000000000000007552 126.0
HKD1_k127_3221141_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2220.0
HKD1_k127_3221141_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1073.0
HKD1_k127_3221141_10 - - - - 0.0000000000000000000000000000000000000000000596 166.0
HKD1_k127_3221141_11 TIGRFAM TIGR00645 family protein - - - 0.000000000000000000000000000000000000001138 154.0
HKD1_k127_3221141_12 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000001635 85.0
HKD1_k127_3221141_13 Major facilitator Superfamily K02575 - - 0.0002559 44.0
HKD1_k127_3221141_2 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 1.519e-296 914.0
HKD1_k127_3221141_3 Major Facilitator Superfamily K02575 - - 6.366e-292 923.0
HKD1_k127_3221141_4 Cytochrome b(N-terminal)/b6/petB - - - 2.56e-245 775.0
HKD1_k127_3221141_5 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 543.0
HKD1_k127_3221141_6 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 293.0
HKD1_k127_3221141_7 Nitrate reductase delta subunit K00373 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006495 261.0
HKD1_k127_3221141_8 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001862 261.0
HKD1_k127_3221141_9 Domain of unknown function DUF29 - - - 0.0000000000000000000000000000000000000000000133 166.0
HKD1_k127_3223474_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 4.986e-218 701.0
HKD1_k127_3223474_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 539.0
HKD1_k127_3223474_2 Belongs to the CarB family K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 368.0
HKD1_k127_3223474_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 312.0
HKD1_k127_3223474_4 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 287.0
HKD1_k127_3223474_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000865 219.0
HKD1_k127_3223474_6 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000004299 173.0
HKD1_k127_3223474_7 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000005313 122.0
HKD1_k127_3223474_8 - - - - 0.00000000000000004335 82.0
HKD1_k127_3223474_9 Domain of unknown function (DUF927) - - - 0.0000000000000004613 81.0
HKD1_k127_3226351_0 DNA methylAse - - - 1.497e-224 728.0
HKD1_k127_3226351_1 PFAM Uncharacterised protein family UPF0175 - - - 0.000000000000000000000000000006013 121.0
HKD1_k127_3226351_2 Antitoxin component of bacterial toxin-antitoxin system, MqsA K07726 - - 0.000000000000000000000000005344 113.0
HKD1_k127_3226351_3 Protein of unknown function (DUF3780) - - - 0.000005686 53.0
HKD1_k127_3230745_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0 1240.0
HKD1_k127_3230745_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 534.0
HKD1_k127_3230745_10 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000001294 60.0
HKD1_k127_3230745_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 389.0
HKD1_k127_3230745_3 pfam chad - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 326.0
HKD1_k127_3230745_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003205 279.0
HKD1_k127_3230745_5 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003171 243.0
HKD1_k127_3230745_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000004918 230.0
HKD1_k127_3230745_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000007475 127.0
HKD1_k127_3230745_8 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.000000000000000000000000001653 114.0
HKD1_k127_3230745_9 KTSC domain - - - 0.000000000000000002303 86.0
HKD1_k127_3243063_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 400.0
HKD1_k127_3243063_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 370.0
HKD1_k127_3243063_2 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 330.0
HKD1_k127_3243063_3 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 326.0
HKD1_k127_3243063_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 299.0
HKD1_k127_3243063_5 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005455 259.0
HKD1_k127_3243063_6 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179,K01637 - 3.2.1.4,4.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003981 278.0
HKD1_k127_3243063_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000001553 91.0
HKD1_k127_3243063_8 - - - - 0.00000002527 58.0
HKD1_k127_3297773_0 Belongs to the ABC transporter superfamily K13896 - - 8.462e-244 765.0
HKD1_k127_3297773_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.642e-233 730.0
HKD1_k127_3297773_10 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 - 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 433.0
HKD1_k127_3297773_11 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 353.0
HKD1_k127_3297773_12 transport system, permease component K13895 - - 0.0000000000000000000000000000000000000000000000000000000001196 204.0
HKD1_k127_3297773_13 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000526 184.0
HKD1_k127_3297773_14 of the cupin superfamily K06995 - - 0.0000000000000000000000000000000002018 134.0
HKD1_k127_3297773_15 - - - - 0.00000000000000000000000000000000608 137.0
HKD1_k127_3297773_16 response regulator, receiver K07814,K13815 - - 0.000000000000000000000005553 106.0
HKD1_k127_3297773_17 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000005004 100.0
HKD1_k127_3297773_18 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000005024 99.0
HKD1_k127_3297773_19 Xylose isomerase domain protein TIM barrel - - - 0.00000000001618 68.0
HKD1_k127_3297773_2 PFAM FAD dependent oxidoreductase K00105,K00111 - 1.1.3.21,1.1.5.3 4.206e-220 694.0
HKD1_k127_3297773_20 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.0000000001335 64.0
HKD1_k127_3297773_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 8.805e-212 666.0
HKD1_k127_3297773_4 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 616.0
HKD1_k127_3297773_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 556.0
HKD1_k127_3297773_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 530.0
HKD1_k127_3297773_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 513.0
HKD1_k127_3297773_8 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 501.0
HKD1_k127_3297773_9 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 486.0
HKD1_k127_333852_0 cellulase activity - - - 0.0 1511.0
HKD1_k127_333852_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 7.535e-320 990.0
HKD1_k127_333852_2 COG0436 Aspartate tyrosine aromatic aminotransferase K00812,K12252 - 2.6.1.1,2.6.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 539.0
HKD1_k127_333852_3 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 421.0
HKD1_k127_333852_4 Specifically methylates the guanosine in position 1516 of 16S rRNA K15984 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.242 0.0000000000000000000000000000000000000000000000000000000004955 210.0
HKD1_k127_333852_5 asparagine synthase K01953 - 6.3.5.4 0.00000000000683 80.0
HKD1_k127_333852_6 - - - - 0.000005069 48.0
HKD1_k127_333852_7 lipolytic protein G-D-S-L family - - - 0.00003057 56.0
HKD1_k127_3349122_0 PFAM Amylo-alpha-16-glucosidase K00705 - 2.4.1.25 1.982e-294 918.0
HKD1_k127_3349122_1 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 6.427e-207 651.0
HKD1_k127_3349122_10 PFAM Transposase IS200 like K07491 - - 0.00000000001646 69.0
HKD1_k127_3349122_2 Chromate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 511.0
HKD1_k127_3349122_3 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 383.0
HKD1_k127_3349122_4 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 374.0
HKD1_k127_3349122_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005385,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006829,GO:0006873,GO:0006875,GO:0006876,GO:0006882,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015086,GO:0015093,GO:0015291,GO:0015318,GO:0015341,GO:0015562,GO:0015684,GO:0015691,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0030003,GO:0034220,GO:0034755,GO:0042592,GO:0042802,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055069,GO:0055073,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070574,GO:0070838,GO:0071577,GO:0071944,GO:0072503,GO:0072507,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:1903874 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 346.0
HKD1_k127_3349122_6 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01911 - 6.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 312.0
HKD1_k127_3349122_7 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 292.0
HKD1_k127_3349122_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001751 265.0
HKD1_k127_3349122_9 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000001096 173.0
HKD1_k127_3354194_0 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 601.0
HKD1_k127_3354194_1 viral genome integration into host DNA - - - 0.00000000000000000000000000000000000000000000000000000000004894 222.0
HKD1_k127_3354194_2 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000007201 192.0
HKD1_k127_3354194_3 COG1961 Site-specific recombinases, DNA invertase Pin homologs K06400 - - 0.0000000000000000000000000000000001958 137.0
HKD1_k127_3354194_4 ATP binding N-terminal - - - 0.000000000000000000006134 96.0
HKD1_k127_3384032_0 short-chain dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 330.0
HKD1_k127_3384032_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001857 268.0
HKD1_k127_3384032_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000005326 149.0
HKD1_k127_338906_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 7.863e-272 848.0
HKD1_k127_338906_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.672e-250 792.0
HKD1_k127_338906_10 Domain of unknown function DUF29 - - - 0.00000000000000000000000000000000006264 139.0
HKD1_k127_338906_11 Protein of unknown function (DUF3018) - - - 0.0000000000000001253 81.0
HKD1_k127_338906_12 5'-nucleotidase, C-terminal domain K01081,K07004,K08693,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.0000000000001841 72.0
HKD1_k127_338906_14 periplasmic K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.000001791 54.0
HKD1_k127_338906_2 de-polymerase K05973 - 3.1.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 558.0
HKD1_k127_338906_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 343.0
HKD1_k127_338906_4 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005616 271.0
HKD1_k127_338906_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001647 238.0
HKD1_k127_338906_6 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000008383 230.0
HKD1_k127_338906_7 LexA-binding, inner membrane-associated putative hydrolase K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000001666 187.0
HKD1_k127_338906_8 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000001852 180.0
HKD1_k127_338906_9 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000000005865 160.0
HKD1_k127_3404535_0 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 436.0
HKD1_k127_3404535_1 Thioredoxin - - - 0.00000000000000000000000000000000000000000757 164.0
HKD1_k127_3404535_2 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000001045 123.0
HKD1_k127_3409738_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 601.0
HKD1_k127_3409738_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 452.0
HKD1_k127_3409738_2 Predicted periplasmic protein (DUF2092) - - - 0.00000000000000000000000000000000000000000000000000009096 196.0
HKD1_k127_3409738_3 long-chain fatty acid transport protein - - - 0.0000000000000000000000001914 116.0
HKD1_k127_3409738_4 - - - - 0.0000002783 61.0
HKD1_k127_3413952_0 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 623.0
HKD1_k127_3413952_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000005621 255.0
HKD1_k127_3413952_2 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000002112 232.0
HKD1_k127_3413952_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000002389 196.0
HKD1_k127_3413952_4 low molecular weight K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000001805 182.0
HKD1_k127_3413952_5 ATPase or kinase K06925 GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000003872 97.0
HKD1_k127_3429601_0 4Fe-4S ferredoxin K18930 - - 0.0 1249.0
HKD1_k127_3429601_1 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114 1.1.1.42 1.71e-264 828.0
HKD1_k127_3429601_10 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 522.0
HKD1_k127_3429601_11 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 489.0
HKD1_k127_3429601_12 Type II/IV secretion system protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 487.0
HKD1_k127_3429601_13 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 416.0
HKD1_k127_3429601_14 Transcriptional regulator K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 376.0
HKD1_k127_3429601_15 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 364.0
HKD1_k127_3429601_16 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 366.0
HKD1_k127_3429601_17 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 360.0
HKD1_k127_3429601_18 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 297.0
HKD1_k127_3429601_19 Late control gene D protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003219 246.0
HKD1_k127_3429601_2 reductase 4Fe-4S K00381 - 1.8.1.2 2.849e-252 788.0
HKD1_k127_3429601_20 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000006745 209.0
HKD1_k127_3429601_21 mRNA catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000007444 208.0
HKD1_k127_3429601_22 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000005179 205.0
HKD1_k127_3429601_23 conserved protein ucp030820 - - - 0.00000000000000000000000000000000000000000000000000000505 194.0
HKD1_k127_3429601_24 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000003004 187.0
HKD1_k127_3429601_25 PFAM Fimbrial assembly K02663 - - 0.000000000000000000000000000000000000002478 154.0
HKD1_k127_3429601_26 PFAM ribosomal protein L31 K02909 - - 0.000000000000000000000000000000000000004416 146.0
HKD1_k127_3429601_27 COG3168 Tfp pilus assembly protein PilP K02665 - - 0.00000000000000000000000000000000006679 141.0
HKD1_k127_3429601_28 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000007193 133.0
HKD1_k127_3429601_29 - - - - 0.00000000000000000000000001101 116.0
HKD1_k127_3429601_3 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.39e-240 750.0
HKD1_k127_3429601_30 Putative Ig domain - - - 0.0000000000000000001587 104.0
HKD1_k127_3429601_4 cluster binding protein K18929 - - 3.776e-224 704.0
HKD1_k127_3429601_5 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.674e-204 642.0
HKD1_k127_3429601_6 type IV pilus secretin PilQ K02666 - - 4.385e-195 632.0
HKD1_k127_3429601_7 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 596.0
HKD1_k127_3429601_8 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 581.0
HKD1_k127_3429601_9 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 523.0
HKD1_k127_3458344_0 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 432.0
HKD1_k127_3458344_1 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 295.0
HKD1_k127_3458344_2 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001711 253.0
HKD1_k127_3458344_3 - - - - 0.000000000000000000000000000000000000001263 152.0
HKD1_k127_3460941_0 Acyl-CoA synthetase (NDP forming) K09181 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 467.0
HKD1_k127_3460941_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 411.0
HKD1_k127_3460941_2 COG0784 FOG CheY-like receiver K02485 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009893,GO:0010556,GO:0010604,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031647,GO:0031648,GO:0032268,GO:0032270,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 372.0
HKD1_k127_3460941_3 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000001853 216.0
HKD1_k127_3460941_4 CYTH K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000004744 211.0
HKD1_k127_3460941_5 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000463 207.0
HKD1_k127_3460941_6 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000003209 207.0
HKD1_k127_3460941_7 cheY-homologous receiver domain - - - 0.0000000000000000000000000000866 121.0
HKD1_k127_3460941_8 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) - - - 0.00000000000000000000000001006 115.0
HKD1_k127_3460941_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0005136 48.0
HKD1_k127_3474256_0 CRISPR-associated protein Csc2 - - - 0.0000000000000000000000000000000000000000000000000000002366 207.0
HKD1_k127_3474256_1 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000001146 170.0
HKD1_k127_3474256_2 DEAD-like helicases superfamily - - - 0.000000000000000000000000000000000000000000004459 184.0
HKD1_k127_3474256_3 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.000000000000000000000000000004307 124.0
HKD1_k127_3474256_4 - - - - 0.00000000000000000000000000000506 128.0
HKD1_k127_3474256_5 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.00000000000000000000000000001909 124.0
HKD1_k127_3474256_6 CRISPR associated protein Cas6 - - - 0.000000000000000005255 93.0
HKD1_k127_3474256_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00002662 58.0
HKD1_k127_3485001_0 'glutamate synthase - - - 0.0 1752.0
HKD1_k127_3485001_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 476.0
HKD1_k127_3485001_2 GHKL domain - - - 0.0000000000000000000000000000000000000000000001399 189.0
HKD1_k127_3485001_3 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000136 134.0
HKD1_k127_35064_0 pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 436.0
HKD1_k127_35064_1 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 408.0
HKD1_k127_35064_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000003967 238.0
HKD1_k127_35064_3 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000001187 167.0
HKD1_k127_35064_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.00000000000000000000000000000000000000000001274 165.0
HKD1_k127_35064_5 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000002364 149.0
HKD1_k127_35064_6 PFAM IS1 transposase - - - 0.000000001835 58.0
HKD1_k127_3539843_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 508.0
HKD1_k127_3539843_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 406.0
HKD1_k127_3539843_2 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000001051 230.0
HKD1_k127_3556733_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 487.0
HKD1_k127_3556733_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 389.0
HKD1_k127_3556733_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 387.0
HKD1_k127_3556733_3 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 321.0
HKD1_k127_3556733_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000003372 194.0
HKD1_k127_3556733_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000002571 152.0
HKD1_k127_3556733_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000009378 120.0
HKD1_k127_3563788_0 Sulfatase-modifying factor enzyme 1 - - - 5.382e-239 766.0
HKD1_k127_3563788_1 - - - - 0.0000000000000000000000000000000000000000000000003697 183.0
HKD1_k127_3563788_2 TIR domain - - - 0.00000000000005697 86.0
HKD1_k127_3563788_3 TIGRFAM malto-oligosyltrehalose trehalohydrolase K01236 - 3.2.1.141 0.0000000007581 60.0
HKD1_k127_3575533_0 amine dehydrogenase activity - - - 1.739e-311 977.0
HKD1_k127_3575533_1 Domain of unknown function (DUF4351) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 360.0
HKD1_k127_3575533_2 NACHT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001038 246.0
HKD1_k127_3575533_3 AAA domain - - - 0.0001133 44.0
HKD1_k127_3586204_0 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 359.0
HKD1_k127_3586204_1 DNA methylase K07316 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000001136 214.0
HKD1_k127_3586204_2 Histidine kinase K07642 - 2.7.13.3 0.0000000000001768 75.0
HKD1_k127_3591396_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 540.0
HKD1_k127_3591396_1 Acyl-CoA synthetase (NDP forming) K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 516.0
HKD1_k127_3591396_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 493.0
HKD1_k127_3591396_3 Acyl-CoA synthetase (NDP forming) K09181 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 412.0
HKD1_k127_3615198_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 1.677e-245 771.0
HKD1_k127_3615198_1 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 4.481e-221 693.0
HKD1_k127_3615198_10 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001165 247.0
HKD1_k127_3615198_11 Belongs to the N(4) N(6)-methyltransferase family K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000007262 225.0
HKD1_k127_3615198_12 protein conserved in bacteria - - - 0.00000000000000000000000000000000008363 136.0
HKD1_k127_3615198_13 - - - - 0.00000000000000000000000000006498 120.0
HKD1_k127_3615198_14 HemX, putative uroporphyrinogen-III C-methyltransferase K02496 - 2.1.1.107 0.0000000000000000000000007571 120.0
HKD1_k127_3615198_15 IMG reference gene - - - 0.000000000000000000000005006 105.0
HKD1_k127_3615198_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 404.0
HKD1_k127_3615198_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 357.0
HKD1_k127_3615198_4 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 325.0
HKD1_k127_3615198_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 306.0
HKD1_k127_3615198_6 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000973 268.0
HKD1_k127_3615198_7 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001467 263.0
HKD1_k127_3615198_8 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000002028 256.0
HKD1_k127_3615198_9 HemY domain protein K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009409 261.0
HKD1_k127_3615305_0 Glycosyl hydrolase family 57 - - - 3.592e-268 832.0
HKD1_k127_3615305_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 2.473e-248 773.0
HKD1_k127_3615305_2 Alpha amylase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 587.0
HKD1_k127_3615305_3 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 548.0
HKD1_k127_3615305_4 DUF218 domain - GO:0000270,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0030203,GO:0031224,GO:0042546,GO:0043164,GO:0043170,GO:0044085,GO:0044425,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901564 - 0.00000000000000000000000000000000000000000000000003172 189.0
HKD1_k127_3615305_5 PFAM IS1 transposase - - - 0.000000000000000000001664 94.0
HKD1_k127_3615305_6 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000001036 53.0
HKD1_k127_3615305_8 PFAM transposase, IS4 family protein - - - 0.000025 48.0
HKD1_k127_3615472_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1119.0
HKD1_k127_3615472_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 4.357e-198 624.0
HKD1_k127_3615472_10 PFAM CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000002169 185.0
HKD1_k127_3615472_11 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000005634 186.0
HKD1_k127_3615472_12 Tol-Pal system TolA K03646 - - 0.0000000000000000000000000000000000000000000615 176.0
HKD1_k127_3615472_13 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000000002261 162.0
HKD1_k127_3615472_14 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000000005061 148.0
HKD1_k127_3615472_15 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000008553 140.0
HKD1_k127_3615472_16 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000002819 130.0
HKD1_k127_3615472_17 Protein of unknown function (DUF3108) - - - 0.0000000000000000003767 97.0
HKD1_k127_3615472_18 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.00000000000005696 83.0
HKD1_k127_3615472_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 507.0
HKD1_k127_3615472_3 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 495.0
HKD1_k127_3615472_4 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 459.0
HKD1_k127_3615472_5 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007629 380.0
HKD1_k127_3615472_6 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 344.0
HKD1_k127_3615472_7 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 342.0
HKD1_k127_3615472_8 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 265.0
HKD1_k127_3615472_9 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002713 262.0
HKD1_k127_3615475_0 unusual protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 552.0
HKD1_k127_3615475_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 513.0
HKD1_k127_3615475_10 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000000000000000008674 150.0
HKD1_k127_3615475_11 - - - - 0.000000000000000000000000000000000001285 143.0
HKD1_k127_3615475_12 hmm pf02371 - - - 0.0000000000000000000000000000009154 124.0
HKD1_k127_3615475_13 RelB antitoxin K07473 - - 0.0000000000000000001032 91.0
HKD1_k127_3615475_14 OmpA family - - - 0.00000000005796 72.0
HKD1_k127_3615475_15 Transport of potassium into the cell K03549 - - 0.0000000001443 63.0
HKD1_k127_3615475_16 Tetratricopeptide repeat - - - 0.000000006172 61.0
HKD1_k127_3615475_17 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00001639 54.0
HKD1_k127_3615475_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 472.0
HKD1_k127_3615475_3 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 460.0
HKD1_k127_3615475_4 3'-5' exonuclease K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 381.0
HKD1_k127_3615475_5 Glucokinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 318.0
HKD1_k127_3615475_6 serine threonine K11915 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000004966 222.0
HKD1_k127_3615475_7 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000006331 194.0
HKD1_k127_3615475_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000002366 170.0
HKD1_k127_3615475_9 Bacterial toxin of type II toxin-antitoxin system, YafQ K19157 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006415,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0034655,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000000000000001609 159.0
HKD1_k127_3653927_0 cysteine synthase K01697 - 4.2.1.22 4.963e-213 669.0
HKD1_k127_3653927_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 395.0
HKD1_k127_3653927_2 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000005227 214.0
HKD1_k127_3653927_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000002268 119.0
HKD1_k127_3653927_4 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000001078 74.0
HKD1_k127_3653927_5 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000006092 69.0
HKD1_k127_3653927_6 - - - - 0.00000000001376 66.0
HKD1_k127_3653927_7 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000002461 70.0
HKD1_k127_3668852_0 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 301.0
HKD1_k127_3668852_1 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008409 256.0
HKD1_k127_3668852_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000004774 223.0
HKD1_k127_3668852_3 protein conserved in bacteria K09928 - - 0.00000000000000000000000000000000000000000001475 168.0
HKD1_k127_3669361_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 1.212e-252 797.0
HKD1_k127_3669361_1 ABC-2 family transporter protein K01992,K13926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 409.0
HKD1_k127_3669361_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 383.0
HKD1_k127_3669361_3 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 367.0
HKD1_k127_3669361_4 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000003845 205.0
HKD1_k127_3669361_5 HpcH/HpaI aldolase/citrate lyase family K08691 GO:0003674,GO:0003824,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872,GO:0047777,GO:0050083 4.1.3.24,4.1.3.25 0.000000000000000000000000000004333 120.0
HKD1_k127_3669361_6 Aspartyl protease - - - 0.0000000000000005324 83.0
HKD1_k127_3670604_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 2.519e-197 631.0
HKD1_k127_3670604_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 439.0
HKD1_k127_3670604_2 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 333.0
HKD1_k127_3670604_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000006301 185.0
HKD1_k127_3675910_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.035e-270 837.0
HKD1_k127_3675910_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 308.0
HKD1_k127_3675910_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000361 266.0
HKD1_k127_3675910_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000006055 156.0
HKD1_k127_3685941_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.176e-255 799.0
HKD1_k127_3685941_1 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 5.255e-242 770.0
HKD1_k127_3685941_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 501.0
HKD1_k127_3685941_3 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001443 282.0
HKD1_k127_3685941_4 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003786 242.0
HKD1_k127_3685941_5 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000000000002396 126.0
HKD1_k127_3685941_6 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000000022 79.0
HKD1_k127_3695055_0 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 427.0
HKD1_k127_3695055_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 382.0
HKD1_k127_3695055_2 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000002513 216.0
HKD1_k127_3695055_3 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000001145 194.0
HKD1_k127_3695055_4 - - - - 0.000000000002002 70.0
HKD1_k127_3724092_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 4.853e-253 788.0
HKD1_k127_3724092_1 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 1.831e-223 715.0
HKD1_k127_3724092_10 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 323.0
HKD1_k127_3724092_11 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 310.0
HKD1_k127_3724092_12 ABC transporter K06021 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009981 273.0
HKD1_k127_3724092_13 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003839 275.0
HKD1_k127_3724092_14 Belongs to the BolA IbaG family - - - 0.0000000000000000001353 91.0
HKD1_k127_3724092_2 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 2.21e-216 683.0
HKD1_k127_3724092_3 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 2.904e-207 654.0
HKD1_k127_3724092_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.015e-202 636.0
HKD1_k127_3724092_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 1.026e-194 615.0
HKD1_k127_3724092_6 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 464.0
HKD1_k127_3724092_7 PFAM conserved K02069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 382.0
HKD1_k127_3724092_8 transport protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 366.0
HKD1_k127_3724092_9 COG0209 Ribonucleotide reductase, alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 330.0
HKD1_k127_3724992_0 Alpha-2-Macroglobulin K06894 - - 0.0 1339.0
HKD1_k127_3724992_1 Homeodomain-like domain - - - 0.0000000000000000000000000000000000003343 146.0
HKD1_k127_3724992_2 transposase or invertase - - - 0.00000000000000000000004688 100.0
HKD1_k127_3724992_3 double-stranded DNA endodeoxyribonuclease activity - - - 0.000000000004851 66.0
HKD1_k127_3724992_4 COG3335 Transposase and inactivated derivatives - - - 0.00000004988 54.0
HKD1_k127_3725081_0 Belongs to the GPI family K01810 - 5.3.1.9 9.314e-292 902.0
HKD1_k127_3725081_1 Circularly permuted ATP-grasp type 2 - - - 5.568e-231 743.0
HKD1_k127_3725081_10 Universal stress protein UspA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009946 248.0
HKD1_k127_3725081_12 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000008972 157.0
HKD1_k127_3725081_13 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000001286 154.0
HKD1_k127_3725081_14 polysaccharide catabolic process K03478 - 3.5.1.105 0.00000000000000000000000000000000000001459 153.0
HKD1_k127_3725081_15 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000001947 113.0
HKD1_k127_3725081_2 Transmembrane secretion effector - - - 2.72e-200 638.0
HKD1_k127_3725081_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 554.0
HKD1_k127_3725081_4 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 401.0
HKD1_k127_3725081_5 Including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 364.0
HKD1_k127_3725081_6 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 326.0
HKD1_k127_3725081_7 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 319.0
HKD1_k127_3725081_8 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005079 278.0
HKD1_k127_3725081_9 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007389 261.0
HKD1_k127_3826270_0 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000002023 182.0
HKD1_k127_3826270_1 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000007993 136.0
HKD1_k127_3826270_2 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.0000000000000002251 84.0
HKD1_k127_3826270_3 membrane - - - 0.00000000006578 66.0
HKD1_k127_383118_0 Pyruvate:ferredoxin oxidoreductase core domain II K18355 - 1.2.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 577.0
HKD1_k127_383118_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 469.0
HKD1_k127_383118_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000051 255.0
HKD1_k127_383118_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K18357 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000004221 227.0
HKD1_k127_383118_4 - - - - 0.0000000000000000000003934 100.0
HKD1_k127_3842877_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000004589 217.0
HKD1_k127_3842877_1 Tubulin like - - - 0.000000000000000000000000000000000000000000004014 177.0
HKD1_k127_3842877_2 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000001913 137.0
HKD1_k127_3842877_3 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000007592 125.0
HKD1_k127_3842877_4 Proton-conducting membrane transporter - - - 0.000000000000000000000005133 104.0
HKD1_k127_3842877_5 Tubulin like - - - 0.00000000000002153 86.0
HKD1_k127_3866002_0 Alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 546.0
HKD1_k127_3866002_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 323.0
HKD1_k127_3866002_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000005055 217.0
HKD1_k127_3866002_3 Pfam:DUF385 - - - 0.00000000000000000000000000001872 123.0
HKD1_k127_3866002_4 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000292 109.0
HKD1_k127_3878981_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 338.0
HKD1_k127_3878981_1 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.00000000000000000000000000000000000000000000000552 173.0
HKD1_k127_3878981_2 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000000000000000000000006163 168.0
HKD1_k127_3878981_3 - - - - 0.000000000000000000000000000000002148 134.0
HKD1_k127_3878981_4 - - - - 0.00000000000000000000000000000001504 129.0
HKD1_k127_3878981_5 Domain of unknown function (DUF4926) - - - 0.0000000000000000007561 89.0
HKD1_k127_3893345_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.802e-218 682.0
HKD1_k127_3893345_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 511.0
HKD1_k127_3893345_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000001896 158.0
HKD1_k127_3893345_11 PFAM IS1 transposase - - - 0.00000000002645 63.0
HKD1_k127_3893345_12 NAD-dependent epimerase dehydratase - - - 0.0000001062 60.0
HKD1_k127_3893345_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 464.0
HKD1_k127_3893345_3 AIR synthase related protein, N-terminal domain K04655 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0018193,GO:0018198,GO:0018249,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046892,GO:0051604,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 450.0
HKD1_k127_3893345_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 365.0
HKD1_k127_3893345_5 Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 300.0
HKD1_k127_3893345_6 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001222 245.0
HKD1_k127_3893345_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000001891 227.0
HKD1_k127_3893345_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000162 215.0
HKD1_k127_3893345_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000121 206.0
HKD1_k127_3928757_0 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 2.721e-286 885.0
HKD1_k127_3928757_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 567.0
HKD1_k127_3928757_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 450.0
HKD1_k127_3946852_0 TonB-dependent Receptor Plug K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 568.0
HKD1_k127_3946852_1 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 319.0
HKD1_k127_3946852_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000005474 182.0
HKD1_k127_3947668_0 Capsule polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002259 243.0
HKD1_k127_3947668_1 Protein of unknown function (DUF433) - - - 0.00000000000000000001208 93.0
HKD1_k127_3947668_2 - - - - 0.00000000000000000002013 95.0
HKD1_k127_3947668_3 Spore maturation protein K06320 - - 0.0000000000000000002551 102.0
HKD1_k127_3965127_0 COG2513 PEP phosphonomutase and related enzymes K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 391.0
HKD1_k127_3965127_1 Conjugal transfer protein TraF - - - 0.00000000000000000165 89.0
HKD1_k127_3965127_2 Leucine-rich repeat (LRR) protein K19613 - - 0.000000000000001098 89.0
HKD1_k127_402394_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005905 263.0
HKD1_k127_402394_1 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000001727 221.0
HKD1_k127_402394_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000293 211.0
HKD1_k127_402394_3 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000008228 206.0
HKD1_k127_402394_4 Putative molybdenum carrier - - - 0.0000000000000000000000000000000000000000000000000915 182.0
HKD1_k127_402394_5 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000214 145.0
HKD1_k127_402394_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000001988 139.0
HKD1_k127_4025420_0 Pfam Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003483 248.0
HKD1_k127_4025420_1 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000004358 188.0
HKD1_k127_4025420_2 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.000000000000000000000000000000007905 129.0
HKD1_k127_4047726_0 Metal binding domain of Ada K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 535.0
HKD1_k127_4047726_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 458.0
HKD1_k127_4047726_10 - - - - 0.0000000000000000008773 94.0
HKD1_k127_4047726_11 Domain of unknown function (DUF3368) - - - 0.00002848 47.0
HKD1_k127_4047726_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000006195 213.0
HKD1_k127_4047726_3 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000005534 156.0
HKD1_k127_4047726_4 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000000004484 123.0
HKD1_k127_4047726_5 nucleotidyltransferase activity - - - 0.00000000000000000000000000008178 119.0
HKD1_k127_4047726_6 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.00000000000000000000000003375 114.0
HKD1_k127_4047726_7 PFAM HupH hydrogenase expression protein K03618 - - 0.000000000000000000000003525 108.0
HKD1_k127_4047726_8 PFAM Uncharacterised protein family UPF0175 - - - 0.000000000000000000002309 96.0
HKD1_k127_4047726_9 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247,K13529 - 3.2.2.21 0.0000000000000000001495 93.0
HKD1_k127_4057471_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 8.678e-238 741.0
HKD1_k127_4057471_1 Helicase conserved C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 578.0
HKD1_k127_4057471_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000003505 211.0
HKD1_k127_4057471_3 Helicase conserved C-terminal domain - - - 0.00000000000000001755 93.0
HKD1_k127_4057471_4 NmrA-like family - - - 0.0000000954 62.0
HKD1_k127_407342_0 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 537.0
HKD1_k127_407342_1 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 505.0
HKD1_k127_407342_2 ABC transporter K01996,K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 350.0
HKD1_k127_407342_3 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 342.0
HKD1_k127_407342_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 314.0
HKD1_k127_4074307_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1313.0
HKD1_k127_4074307_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 579.0
HKD1_k127_4074307_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000003058 176.0
HKD1_k127_4077733_0 PFAM Patatin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 541.0
HKD1_k127_4077733_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 362.0
HKD1_k127_4087796_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.0 1007.0
HKD1_k127_4087796_1 Aminotransferase, class I K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003315 278.0
HKD1_k127_4087796_2 PFAM methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000006992 213.0
HKD1_k127_4090293_0 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 324.0
HKD1_k127_4090293_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000005688 172.0
HKD1_k127_4090293_2 Cytochrome oxidase maturation protein cbb3-type - - - 0.00000000000003236 77.0
HKD1_k127_4090585_0 Transposase IS66 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 472.0
HKD1_k127_4090585_1 PIN domain - - - 0.0000000000001722 70.0
HKD1_k127_4090585_2 - - - - 0.00001077 47.0
HKD1_k127_4090585_3 PIN domain - - - 0.00001369 49.0
HKD1_k127_4090585_4 Transposase DDE domain - - - 0.00008775 46.0
HKD1_k127_4095958_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 6.347e-270 841.0
HKD1_k127_4095958_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 1.278e-269 838.0
HKD1_k127_4095958_2 Diguanylate cyclase - - - 3.466e-222 722.0
HKD1_k127_4095958_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 3.875e-209 669.0
HKD1_k127_4095958_4 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 550.0
HKD1_k127_4095958_5 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001734 256.0
HKD1_k127_4095958_6 cell division protein - - - 0.0000000001465 71.0
HKD1_k127_4107421_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 342.0
HKD1_k127_4107421_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239 - - 0.0000000000000000000001897 97.0
HKD1_k127_4107421_2 - - - - 0.000000000000002342 82.0
HKD1_k127_4112980_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 478.0
HKD1_k127_4112980_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006635 279.0
HKD1_k127_4112980_2 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000001194 226.0
HKD1_k127_4112980_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000004809 224.0
HKD1_k127_4112980_4 Insulinase (Peptidase family M16) K00960,K07263 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000001459 206.0
HKD1_k127_4112980_5 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000116 148.0
HKD1_k127_4112980_6 Required for the activity of the bacterial periplasmic transport system of putrescine K11069 - - 0.0000000000000000005698 88.0
HKD1_k127_4127563_0 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 606.0
HKD1_k127_4127563_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000007228 192.0
HKD1_k127_4139827_0 double-stranded DNA endodeoxyribonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008583 247.0
HKD1_k127_4139827_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.000000000000000000000000000000000000000000000000005233 185.0
HKD1_k127_4139827_2 PIN domain - - - 0.000000000000000000000000002165 114.0
HKD1_k127_4139827_3 positive regulation of growth - - - 0.000000000000000003317 86.0
HKD1_k127_4139827_4 Transposase IS200 like - - - 0.000000000000003584 75.0
HKD1_k127_4139827_5 PIN domain - - - 0.0000000000001006 72.0
HKD1_k127_4139827_6 PIN domain - - - 0.0000002242 56.0
HKD1_k127_4139827_7 PIN domain - - - 0.00001976 48.0
HKD1_k127_4139827_8 SpoVT / AbrB like domain - - - 0.0001018 47.0
HKD1_k127_4139827_9 CHAT domain - - - 0.0006682 47.0
HKD1_k127_4196951_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.399e-221 694.0
HKD1_k127_4196951_1 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 458.0
HKD1_k127_4196951_2 Transposase - - - 0.00000000000000000000000000000000000000001708 159.0
HKD1_k127_4201520_0 Transposase - - - 0.000000000000000000000000000000000000000000001069 171.0
HKD1_k127_4201520_1 Protein of unknown function (DUF2721) - - - 0.0000000000000008793 80.0
HKD1_k127_4201520_2 Protein of unknown function (DUF2721) - - - 0.00000000000006507 74.0
HKD1_k127_4201520_3 PFAM Transposase DDE domain - - - 0.00000001316 55.0
HKD1_k127_4201520_4 COG3293 Transposase and inactivated derivatives - - - 0.00000546 48.0
HKD1_k127_4201520_5 Acetyltransferase (GNAT) domain - - - 0.0006591 45.0
HKD1_k127_4212414_0 FAD-NAD(P)-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 488.0
HKD1_k127_4212414_1 Helix-turn-helix domain of transposase family ISL3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 386.0
HKD1_k127_4212414_10 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000004766 93.0
HKD1_k127_4212414_11 Serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 0.000000002553 63.0
HKD1_k127_4212414_12 Rhodanese Homology Domain - - - 0.000134 47.0
HKD1_k127_4212414_13 Serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 0.0001616 46.0
HKD1_k127_4212414_2 Transcriptional regulator K13635 - - 0.00000000000000000000000000000000000000000000000000000000000000000004427 237.0
HKD1_k127_4212414_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000001476 231.0
HKD1_k127_4212414_4 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000001721 214.0
HKD1_k127_4212414_5 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000002754 170.0
HKD1_k127_4212414_6 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000001759 173.0
HKD1_k127_4212414_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000004646 158.0
HKD1_k127_4212414_8 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.000000000000000000000000000234 121.0
HKD1_k127_4212414_9 EAL domain - - - 0.0000000000000000000000001499 117.0
HKD1_k127_4214530_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1208.0
HKD1_k127_4214530_1 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847 - 5.4.99.2 6.659e-244 773.0
HKD1_k127_4214530_10 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000000000000000000002543 231.0
HKD1_k127_4214530_11 pfam ammecr1 K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000002208 226.0
HKD1_k127_4214530_12 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000001487 191.0
HKD1_k127_4214530_13 - - - - 0.0000000000000000000000000000000000000001254 153.0
HKD1_k127_4214530_14 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000001106 146.0
HKD1_k127_4214530_15 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.000000000000000000000000000009982 124.0
HKD1_k127_4214530_16 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000002696 120.0
HKD1_k127_4214530_17 - - - - 0.0000000000000000000000000122 115.0
HKD1_k127_4214530_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.00000000000000000000000003667 108.0
HKD1_k127_4214530_19 manually curated - - - 0.00000000005887 65.0
HKD1_k127_4214530_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 5.358e-221 689.0
HKD1_k127_4214530_20 Chorismate mutase K00014,K00891,K04092,K04516 - 1.1.1.25,2.7.1.71,5.4.99.5 0.00001035 48.0
HKD1_k127_4214530_3 Radical SAM superfamily K04069 - 1.97.1.4 3.123e-201 631.0
HKD1_k127_4214530_4 MGS-like domain - - - 3.144e-195 623.0
HKD1_k127_4214530_5 Belongs to the TelA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 436.0
HKD1_k127_4214530_6 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 347.0
HKD1_k127_4214530_7 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001364 278.0
HKD1_k127_4214530_8 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001101 263.0
HKD1_k127_4214530_9 PFAM 5-bromo-4-chloroindolyl phosphate hydrolysis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001299 265.0
HKD1_k127_4232423_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.568e-266 827.0
HKD1_k127_4232423_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.075e-240 747.0
HKD1_k127_4232423_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000001758 173.0
HKD1_k127_4232423_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000004019 156.0
HKD1_k127_4232423_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000002105 142.0
HKD1_k127_4232423_13 ATP synthase I chain K02116 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000004381 83.0
HKD1_k127_4232423_14 PFAM YcgL domain K09902 - - 0.00000000000005213 74.0
HKD1_k127_4232423_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 366.0
HKD1_k127_4232423_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 357.0
HKD1_k127_4232423_4 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 324.0
HKD1_k127_4232423_5 ATPases involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 319.0
HKD1_k127_4232423_6 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003326 242.0
HKD1_k127_4232423_7 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000002491 243.0
HKD1_k127_4232423_8 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000004219 206.0
HKD1_k127_4232423_9 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000008989 181.0
HKD1_k127_4236820_0 PFAM AMP-dependent synthetase and ligase K00666 - - 3.01e-236 747.0
HKD1_k127_4236820_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009471 246.0
HKD1_k127_4236820_2 O-Antigen ligase - - - 0.0004424 52.0
HKD1_k127_4239499_0 AAA domain K03496 - - 0.00000000000000000000000000000000000000000000000000000000006083 219.0
HKD1_k127_4239499_1 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000005607 206.0
HKD1_k127_4239499_2 Transposase DDE domain - - - 0.000000000000000000000000000001192 122.0
HKD1_k127_4239499_3 Belongs to the UPF0758 family K03630 - - 0.0000000000000000007244 91.0
HKD1_k127_4239499_4 double-stranded DNA endodeoxyribonuclease activity - - - 0.000000000001958 72.0
HKD1_k127_4239499_5 Protein of unknown function (DUF2887) - - - 0.000000000006347 68.0
HKD1_k127_4239499_6 Belongs to the UPF0758 family K03630 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000004463 62.0
HKD1_k127_4239499_7 FAD dependent oxidoreductase - - - 0.0009065 44.0
HKD1_k127_4239499_8 type I restriction modification DNA specificity domain - - - 0.0009163 43.0
HKD1_k127_4245009_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 551.0
HKD1_k127_4256305_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 1.027e-276 869.0
HKD1_k127_4256305_1 small GTP-binding protein K02355 - - 3.1e-271 852.0
HKD1_k127_4256305_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 492.0
HKD1_k127_4256305_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 406.0
HKD1_k127_4256305_4 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 363.0
HKD1_k127_4256305_5 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000004097 225.0
HKD1_k127_4256305_6 Protein of unknown function (DUF1244) K09948 - - 0.000000000000000000000000000000000000000203 151.0
HKD1_k127_4256305_7 Putative restriction endonuclease - - - 0.0000000000001056 76.0
HKD1_k127_4256305_8 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.000002439 51.0
HKD1_k127_4256305_9 Ntpase (Nacht family) - - - 0.0001222 46.0
HKD1_k127_4290049_0 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005451 282.0
HKD1_k127_4290049_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000001621 244.0
HKD1_k127_4290049_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000004234 233.0
HKD1_k127_4290049_3 - - - - 0.00000000000000000006474 93.0
HKD1_k127_4290049_4 - - - - 0.000000006584 59.0
HKD1_k127_4290049_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000004232 51.0
HKD1_k127_4315243_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 3.625e-196 624.0
HKD1_k127_4315243_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772,K19696 - 2.4.2.28,2.4.2.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 340.0
HKD1_k127_4315243_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000002834 119.0
HKD1_k127_4315243_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000008583 81.0
HKD1_k127_4326429_0 Baseplate J-like protein - - - 1.286e-202 666.0
HKD1_k127_4326429_1 Phage late control gene D protein (GPD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 381.0
HKD1_k127_4326429_10 Protein phosphatase 2C K20074 GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 0.00000000000000000000000000000000000000000006302 172.0
HKD1_k127_4326429_11 Lysin motif - - - 0.00000000000000000000000000000000000000001455 161.0
HKD1_k127_4326429_12 Gene 25-like lysozyme K06903 - - 0.0000000000000000000000000000000000000003109 153.0
HKD1_k127_4326429_13 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000001554 119.0
HKD1_k127_4326429_14 PFAM Phage tail protein (Tail_P2_I) - - - 0.0000000000000000002728 97.0
HKD1_k127_4326429_15 - - - - 0.00000000000004111 75.0
HKD1_k127_4326429_16 Hep Hag repeat protein K09942,K21449 - - 0.00000000002493 75.0
HKD1_k127_4326429_17 PFAM Forkhead-associated - - - 0.00000003456 64.0
HKD1_k127_4326429_18 COG1716 FOG FHA domain - - - 0.0000001947 64.0
HKD1_k127_4326429_19 protein ubiquitination K05288 GO:0000151,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0019005,GO:0019222,GO:0019538,GO:0019899,GO:0019941,GO:0030162,GO:0030163,GO:0031461,GO:0031625,GO:0032991,GO:0043161,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044424,GO:0044464,GO:0050789,GO:0051171,GO:0051246,GO:0051603,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234 - 0.000003149 60.0
HKD1_k127_4326429_2 PAAR motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000009281 236.0
HKD1_k127_4326429_20 Belongs to the ompA family - - - 0.00006775 53.0
HKD1_k127_4326429_21 Pfam:DUF1311 - - - 0.0002922 49.0
HKD1_k127_4326429_22 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.0009656 49.0
HKD1_k127_4326429_3 PFAM Phage-related baseplate assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001799 239.0
HKD1_k127_4326429_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000018 248.0
HKD1_k127_4326429_5 Baseplate J-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005888 239.0
HKD1_k127_4326429_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000001157 218.0
HKD1_k127_4326429_7 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000000000000000000000000000000000000000002558 205.0
HKD1_k127_4326429_8 cytolysis by virus of host cell K01185 - 3.2.1.17 0.0000000000000000000000000000000000000000000000000000352 191.0
HKD1_k127_4326429_9 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000004956 181.0
HKD1_k127_4338633_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 7.844e-254 796.0
HKD1_k127_4338633_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 375.0
HKD1_k127_4338633_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000004878 219.0
HKD1_k127_4338633_3 Polyhydroxyalkanoate granule-associated protein - - - 0.0000000000000002168 81.0
HKD1_k127_4338633_4 Bacterial protein of unknown function (DUF945) - - - 0.00000000004793 75.0
HKD1_k127_4338633_5 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.00000001803 58.0
HKD1_k127_4338633_6 Tetratricopeptide TPR_2 repeat protein - - - 0.0005064 46.0
HKD1_k127_4344196_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 395.0
HKD1_k127_4344196_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002064 254.0
HKD1_k127_4344196_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000002304 239.0
HKD1_k127_4344196_3 Protein of unknown function (DUF1461) - - - 0.0000000000000000000000000000000000000000000000000000001617 204.0
HKD1_k127_4344196_4 Endonuclease Exonuclease phosphatase K07004 - - 0.00000000000000000000000000000000000000000003467 169.0
HKD1_k127_4373568_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 464.0
HKD1_k127_4373568_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 401.0
HKD1_k127_4373568_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 310.0
HKD1_k127_4373568_3 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000337 245.0
HKD1_k127_4373568_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000003424 179.0
HKD1_k127_4390132_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1478.0
HKD1_k127_4390132_1 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 512.0
HKD1_k127_4390132_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000744 344.0
HKD1_k127_4390132_3 Psort location CytoplasmicMembrane, score 10.00 K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 282.0
HKD1_k127_4390132_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000005664 209.0
HKD1_k127_4390132_5 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000143 201.0
HKD1_k127_4390132_6 Transcriptional regulator K13634 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000001206 137.0
HKD1_k127_4390132_7 Belongs to the MtfA family K09933 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000003598 136.0
HKD1_k127_4390132_8 Protein of unknown function (DUF2281) - - - 0.0000000324 57.0
HKD1_k127_4394994_0 PFAM transposase, mutator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 505.0
HKD1_k127_4394994_1 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000002347 92.0
HKD1_k127_4416554_0 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 3.553e-308 956.0
HKD1_k127_4416554_1 Dehydratase K14449,K18290 - 4.2.1.148,4.2.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 452.0
HKD1_k127_4419842_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 627.0
HKD1_k127_4419842_1 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 446.0
HKD1_k127_4419842_10 Response regulator, receiver K11443 - - 0.000000000000000000000000000000000000000002608 158.0
HKD1_k127_4419842_11 PFAM IS1 transposase K07480 - - 0.0000000000000000000000000000000000000003518 150.0
HKD1_k127_4419842_12 - - - - 0.000000000000000000000000000000007095 132.0
HKD1_k127_4419842_13 PFAM IS1 transposase K07480 - - 0.000000000000007712 75.0
HKD1_k127_4419842_14 InsA C-terminal domain - - - 0.000000000001189 70.0
HKD1_k127_4419842_15 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000003787 61.0
HKD1_k127_4419842_2 HpcH/HpaI aldolase/citrate lyase family K01644,K18292 - 4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 381.0
HKD1_k127_4419842_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 367.0
HKD1_k127_4419842_4 NAD dependent epimerase/dehydratase family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 325.0
HKD1_k127_4419842_5 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 305.0
HKD1_k127_4419842_6 MltA-interacting protein MipA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001185 271.0
HKD1_k127_4419842_7 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009811 251.0
HKD1_k127_4419842_8 Beta-ketoacyl synthase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007424 231.0
HKD1_k127_4419842_9 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000007817 216.0
HKD1_k127_4437016_0 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 368.0
HKD1_k127_4437016_1 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000000000000000002559 212.0
HKD1_k127_4437016_2 Protein of unknown function (DUF3987) - - - 0.00000000000000000000001025 118.0
HKD1_k127_445365_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 503.0
HKD1_k127_445365_1 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004129 269.0
HKD1_k127_445365_2 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009062 282.0
HKD1_k127_445365_3 Adenosine/AMP deaminase - - - 0.000000000000004752 85.0
HKD1_k127_445365_4 'glutamate synthase - - - 0.00000000000001758 76.0
HKD1_k127_4463372_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 404.0
HKD1_k127_4463372_1 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000012 252.0
HKD1_k127_4463372_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0006281 49.0
HKD1_k127_4471386_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 350.0
HKD1_k127_4471386_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008282 329.0
HKD1_k127_4471386_2 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000000000000000000000000002096 220.0
HKD1_k127_4480204_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 4.722e-225 710.0
HKD1_k127_4480204_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 381.0
HKD1_k127_4480204_2 Transglycosylase SLT domain K01185 - 3.2.1.17 0.0000000000000000000000000000000000000000000007344 174.0
HKD1_k127_4480204_3 transglycosylase - - - 0.0000000000000000000000000000000000000000002882 169.0
HKD1_k127_4480204_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000008051 76.0
HKD1_k127_4508853_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 489.0
HKD1_k127_4508853_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 377.0
HKD1_k127_4508853_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000002583 240.0
HKD1_k127_4508853_3 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000002251 168.0
HKD1_k127_4508853_4 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000006872 111.0
HKD1_k127_4523403_0 NMT1-like family K15576 - - 2.836e-206 649.0
HKD1_k127_4523403_1 Nitrate ABC transporter inner membrane subunit K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 417.0
HKD1_k127_4523403_2 SMART cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003889 243.0
HKD1_k127_4523403_3 PFAM response regulator receiver K07183 - - 0.00000000000000000000000000000000000000000000000000000000000000003673 228.0
HKD1_k127_4523403_4 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K15578 - - 0.0000000000000000000000000000004637 125.0
HKD1_k127_45285_0 PFAM transposase IS66 K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000009387 231.0
HKD1_k127_45285_1 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000002063 194.0
HKD1_k127_45285_2 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000003056 60.0
HKD1_k127_45285_3 methyltransferase - - - 0.0002003 45.0
HKD1_k127_4554984_0 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 380.0
HKD1_k127_4554984_1 STAS domain K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002641 295.0
HKD1_k127_4565562_0 ATP-dependent DNA helicase RecQ K03169 - 5.99.1.2 0.0 1561.0
HKD1_k127_4565562_1 Elongator protein 3, MiaB family, Radical SAM K04034 - 1.21.98.3 5.791e-282 870.0
HKD1_k127_4565562_10 Transposase - - - 0.0000000000000000001618 95.0
HKD1_k127_4565562_11 PFAM IS1 transposase K07480 - - 0.000000000000000001085 87.0
HKD1_k127_4565562_12 Transposase - - - 0.00000000000000002034 85.0
HKD1_k127_4565562_13 PFAM transposase IS66 K07484 - - 0.000000000000003558 78.0
HKD1_k127_4565562_14 Transposase - - - 0.0000003203 51.0
HKD1_k127_4565562_15 MmgE/PrpD family - - - 0.000307 45.0
HKD1_k127_4565562_16 PEP-CTERM motif - - - 0.0005216 51.0
HKD1_k127_4565562_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.048e-231 726.0
HKD1_k127_4565562_3 ABC transporter transmembrane region K06147 - - 2.738e-215 683.0
HKD1_k127_4565562_4 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 549.0
HKD1_k127_4565562_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 400.0
HKD1_k127_4565562_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 368.0
HKD1_k127_4565562_7 hopanoid biosynthesis associated protein HpnK K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 309.0
HKD1_k127_4565562_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002065 235.0
HKD1_k127_4565562_9 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000006802 231.0
HKD1_k127_4577328_0 Acyl-CoA synthetase (NDP forming) K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 397.0
HKD1_k127_4577328_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000002057 203.0
HKD1_k127_4577328_2 CTP synthase N-terminus K01937 GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.00000000000000000000000000000000000000000000000000000247 194.0
HKD1_k127_4588773_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 437.0
HKD1_k127_4588773_1 Glycerophosphoryl diester phosphodiesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002938 272.0
HKD1_k127_4588773_2 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008475 262.0
HKD1_k127_4588773_3 dehydratase K17865 - 4.2.1.55 0.000000000000000000000000000000000000000000000000000000001658 206.0
HKD1_k127_4588773_4 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000002218 138.0
HKD1_k127_4588773_5 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000007912 123.0
HKD1_k127_4588773_6 PFAM Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000002743 99.0
HKD1_k127_4598253_0 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 421.0
HKD1_k127_4598253_1 PFAM Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 344.0
HKD1_k127_4598253_10 PFAM transposase, IS4 family protein - - - 0.00004291 52.0
HKD1_k127_4598253_11 addiction module antidote protein HigA - - - 0.00004968 51.0
HKD1_k127_4598253_2 Carboxypeptidase regulatory-like domain K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001407 250.0
HKD1_k127_4598253_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000008156 222.0
HKD1_k127_4598253_4 Scavenger mRNA decapping enzyme C-term binding - - - 0.00000000000000000000000000000000000000000000000000000002357 199.0
HKD1_k127_4598253_5 PFAM cytochrome c, class I K08738 - - 0.0000000000000000000000000000001493 130.0
HKD1_k127_4598253_6 HNH endonuclease K07454 - - 0.00000000000000000000000000209 117.0
HKD1_k127_4598253_7 Phosphoglycerate mutase family - - - 0.00000002436 61.0
HKD1_k127_4598253_8 PFAM transposase, IS4 family protein - - - 0.000001867 51.0
HKD1_k127_4598253_9 general secretion pathway protein - - - 0.00002301 49.0
HKD1_k127_4634767_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002491 252.0
HKD1_k127_4634767_1 - - - - 0.000000000000000000000000000005664 124.0
HKD1_k127_4634767_3 - - - - 0.0000001875 59.0
HKD1_k127_4662657_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 5.802e-267 827.0
HKD1_k127_4662657_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 564.0
HKD1_k127_4662657_2 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000007882 177.0
HKD1_k127_4674845_0 NACHT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 509.0
HKD1_k127_4674845_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000046 163.0
HKD1_k127_4674845_2 Sulfatase-modifying factor enzyme 1 - - - 0.00000000004261 76.0
HKD1_k127_4700792_0 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 455.0
HKD1_k127_4700792_1 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 325.0
HKD1_k127_4700792_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003261 279.0
HKD1_k127_4700792_3 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000009948 224.0
HKD1_k127_4700792_4 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.000000000000000000000000003812 121.0
HKD1_k127_4700792_5 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.00000000007479 70.0
HKD1_k127_4703029_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 8.575e-252 781.0
HKD1_k127_4703029_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.842e-219 686.0
HKD1_k127_4703029_10 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000006601 104.0
HKD1_k127_4703029_11 Ribosomal protein L30 K02907 - - 0.0000000000000000000004061 97.0
HKD1_k127_4703029_12 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001547 70.0
HKD1_k127_4703029_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 468.0
HKD1_k127_4703029_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 317.0
HKD1_k127_4703029_4 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005043 249.0
HKD1_k127_4703029_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000002691 230.0
HKD1_k127_4703029_6 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000003412 205.0
HKD1_k127_4703029_7 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000001056 201.0
HKD1_k127_4703029_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000006949 188.0
HKD1_k127_4703029_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000004251 168.0
HKD1_k127_4704908_0 PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A K01908 - 6.2.1.17 1.787e-289 900.0
HKD1_k127_4704908_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.969e-214 672.0
HKD1_k127_4704908_10 Uncharacterized ACR, COG1993 - - - 0.00000000000000000000000000000000003135 144.0
HKD1_k127_4704908_11 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503,K19710,K21220 - 2.5.1.3,2.7.7.53 0.0000000000000000000000002327 111.0
HKD1_k127_4704908_12 - - - - 0.0000000000179 68.0
HKD1_k127_4704908_13 Helix-turn-helix domain - - - 0.0000000003744 61.0
HKD1_k127_4704908_2 collagen metabolic process K08677 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008338 594.0
HKD1_k127_4704908_3 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 581.0
HKD1_k127_4704908_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 518.0
HKD1_k127_4704908_5 Pfam Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 520.0
HKD1_k127_4704908_6 PFAM Prenyltransferase squalene oxidase K05956 - 2.5.1.60 0.000000000000000000000000000000000000000000002065 175.0
HKD1_k127_4704908_7 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000002536 166.0
HKD1_k127_4704908_8 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000003601 151.0
HKD1_k127_4704908_9 Universal stress protein - - - 0.0000000000000000000000000000000000001088 145.0
HKD1_k127_4734369_0 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 438.0
HKD1_k127_4734369_1 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 407.0
HKD1_k127_4734369_2 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 289.0
HKD1_k127_4734369_3 Resolvase domain - - - 0.000000000000000000000000000006095 120.0
HKD1_k127_4734369_4 transposase activity - - - 0.00000000000000001176 87.0
HKD1_k127_4781732_0 TIGRFAM Nitrogenase cofactor biosynthesis protein NifB K02585 - - 6.059e-211 666.0
HKD1_k127_4781732_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 354.0
HKD1_k127_4781732_2 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003539 250.0
HKD1_k127_4781732_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000004263 140.0
HKD1_k127_4781732_4 Acetyltransferase (GNAT) domain - - - 0.0000000000001918 83.0
HKD1_k127_4781732_5 GDSL-like Lipase/Acylhydrolase - - - 0.0000000004383 72.0
HKD1_k127_4799155_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.176e-316 979.0
HKD1_k127_4799155_1 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 5.696e-216 694.0
HKD1_k127_4799155_10 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000001678 187.0
HKD1_k127_4799155_11 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000004323 164.0
HKD1_k127_4799155_12 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000004469 115.0
HKD1_k127_4799155_13 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000007953 98.0
HKD1_k127_4799155_14 Dodecin K09165 - - 0.000000000000000000002766 96.0
HKD1_k127_4799155_15 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000003029 96.0
HKD1_k127_4799155_16 Nucleotidyltransferase domain K07076 - - 0.000000000000001315 82.0
HKD1_k127_4799155_18 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000008388 69.0
HKD1_k127_4799155_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 531.0
HKD1_k127_4799155_20 Domain of unknown function (DUF4160) - - - 0.00002409 48.0
HKD1_k127_4799155_21 nuclease activity K18828 - - 0.0008002 42.0
HKD1_k127_4799155_3 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 411.0
HKD1_k127_4799155_4 Belongs to the WrbA family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 288.0
HKD1_k127_4799155_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000000001238 245.0
HKD1_k127_4799155_7 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008494 244.0
HKD1_k127_4799155_8 Protein of unknown function (DUF1285) K09986 - - 0.00000000000000000000000000000000000000000000000000000000505 205.0
HKD1_k127_4799155_9 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA K10763 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000009402 206.0
HKD1_k127_4803015_0 carbohydrate binding K00702 - 2.4.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 614.0
HKD1_k127_4803015_1 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000004575 210.0
HKD1_k127_4820036_0 Belongs to the peptidase S16 family - - - 1.217e-281 887.0
HKD1_k127_4820036_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000004849 121.0
HKD1_k127_4864333_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.394e-267 830.0
HKD1_k127_4864333_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 535.0
HKD1_k127_4864333_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 507.0
HKD1_k127_4864333_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 505.0
HKD1_k127_4864333_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 428.0
HKD1_k127_4864333_5 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 390.0
HKD1_k127_4864333_6 branched-chain amino acid transport K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 344.0
HKD1_k127_4864333_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 342.0
HKD1_k127_4864333_8 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000288 284.0
HKD1_k127_4864333_9 sulfur carrier activity K04085 - - 0.0000000000000000003826 90.0
HKD1_k127_4869673_0 ABC1 family K03688 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 562.0
HKD1_k127_4869673_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 356.0
HKD1_k127_4869673_2 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000003559 203.0
HKD1_k127_4869673_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000001867 148.0
HKD1_k127_4869673_4 alpha beta - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000008308 82.0
HKD1_k127_4869673_5 Helix-hairpin-helix motif K02237 - - 0.0000000000000002873 83.0
HKD1_k127_4869673_6 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.00000000945 62.0
HKD1_k127_4869673_7 Putative cyclase - - - 0.0000002746 53.0
HKD1_k127_4936994_0 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 409.0
HKD1_k127_4936994_1 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 291.0
HKD1_k127_4936994_2 glycoside hydrolase family 81 - - - 0.0003688 44.0
HKD1_k127_4938835_0 AMP-binding enzyme C-terminal domain K00666 - - 5.011e-197 632.0
HKD1_k127_4938835_1 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 345.0
HKD1_k127_4938835_2 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.00000000000000000000000000000000000000000000000000004737 193.0
HKD1_k127_4938835_3 Lipase (class 3) - - - 0.00000001766 57.0
HKD1_k127_4939276_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 554.0
HKD1_k127_4939276_1 Metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008832 416.0
HKD1_k127_4939276_10 Dehydrogenase - - - 0.0000000000001086 85.0
HKD1_k127_4939276_11 Catalyzes the reduction of fatty acyl-CoA to fatty alcohols K13356 - 1.2.1.84 0.0000000000001746 84.0
HKD1_k127_4939276_12 Domain of unknown function (DUF4442) - - - 0.0000000000004358 72.0
HKD1_k127_4939276_13 Protein of unknown function (DUF1499) - - - 0.0000000002332 67.0
HKD1_k127_4939276_14 - K07484 - - 0.0009065 44.0
HKD1_k127_4939276_2 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 381.0
HKD1_k127_4939276_3 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 349.0
HKD1_k127_4939276_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000001078 247.0
HKD1_k127_4939276_5 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001201 235.0
HKD1_k127_4939276_6 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000008939 234.0
HKD1_k127_4939276_7 Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) K05774 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006015,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019634,GO:0019637,GO:0019674,GO:0019693,GO:0033863,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046496,GO:0046835,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.23 0.000000000000000000000000000000000000000000000000000002961 196.0
HKD1_k127_4939276_8 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000002037 190.0
HKD1_k127_4939276_9 COG0575 CDP-diglyceride synthetase - - - 0.000000000000000000000000000000000000000005464 159.0
HKD1_k127_5082489_0 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 362.0
HKD1_k127_5082489_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004504 271.0
HKD1_k127_5082489_2 Von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002276 256.0
HKD1_k127_5082489_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000003132 164.0
HKD1_k127_5082489_4 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000002381 138.0
HKD1_k127_5093448_0 Belongs to the bacterial solute-binding protein 3 family K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 510.0
HKD1_k127_5093448_1 Binding-protein-dependent transport system inner membrane component K02029,K09971,K10002,K10037 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 500.0
HKD1_k127_5093448_2 Binding-protein-dependent transport system inner membrane component K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 492.0
HKD1_k127_5093448_3 (ABC) transporter K02028,K02029,K09972,K10004,K10010 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000001247 246.0
HKD1_k127_5108862_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1016.0
HKD1_k127_5108862_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 571.0
HKD1_k127_5108862_2 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000000000007609 136.0
HKD1_k127_5112472_0 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.0 1468.0
HKD1_k127_5112472_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1391.0
HKD1_k127_5112472_10 Domain of unknown function (DUF4124) - - - 0.000000003845 63.0
HKD1_k127_5112472_2 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 1.621e-289 898.0
HKD1_k127_5112472_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 561.0
HKD1_k127_5112472_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 357.0
HKD1_k127_5112472_5 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000003618 238.0
HKD1_k127_5112472_6 stress protein K05791 - - 0.000000000000000000000000000000000000000000000000000000002989 206.0
HKD1_k127_5112472_9 Protein of unknown function (DUF2283) - - - 0.0000000000000001001 82.0
HKD1_k127_5132192_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 1.505e-293 912.0
HKD1_k127_5132192_1 Glycosyl transferase family 21 - - - 6.077e-282 883.0
HKD1_k127_5132192_10 - - - - 0.000000002169 64.0
HKD1_k127_5132192_11 - - - - 0.000006674 55.0
HKD1_k127_5132192_2 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 499.0
HKD1_k127_5132192_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 479.0
HKD1_k127_5132192_4 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 449.0
HKD1_k127_5132192_5 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 350.0
HKD1_k127_5132192_6 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000428 276.0
HKD1_k127_5132192_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000209 243.0
HKD1_k127_5132192_8 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000004535 220.0
HKD1_k127_5132192_9 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000002615 82.0
HKD1_k127_5132527_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1146.0
HKD1_k127_5132527_1 Tex-like protein N-terminal domain K06959 - - 1.63e-322 1005.0
HKD1_k127_5132527_10 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.00000000000000000000000001119 114.0
HKD1_k127_5132527_11 - - - - 0.000000000000000000002493 99.0
HKD1_k127_5132527_12 - - - - 0.00003529 49.0
HKD1_k127_5132527_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 5.897e-270 847.0
HKD1_k127_5132527_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 543.0
HKD1_k127_5132527_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 359.0
HKD1_k127_5132527_5 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000003009 267.0
HKD1_k127_5132527_6 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003956 248.0
HKD1_k127_5132527_7 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000001653 231.0
HKD1_k127_5132527_8 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000001857 207.0
HKD1_k127_5132527_9 PFAM Pentapeptide - - - 0.0000000000000000000000000000000000000000001621 169.0
HKD1_k127_5143601_0 Belongs to the AdoMet synthase family K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 505.0
HKD1_k127_5143601_1 esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 399.0
HKD1_k127_5143601_2 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 337.0
HKD1_k127_5176869_1 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 464.0
HKD1_k127_5176869_2 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 375.0
HKD1_k127_5176869_3 - K07498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 293.0
HKD1_k127_5176869_4 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006255 262.0
HKD1_k127_5176869_5 PFAM Transposase K07494 - - 0.0000000000000000000000000000000000000000000000000000000002194 216.0
HKD1_k127_5176869_6 PFAM PRC-barrel domain protein - - - 0.00000000000000000000000000000000003626 138.0
HKD1_k127_5176869_7 DDE_Tnp_1-associated - - - 0.0000000000000000000000000000003093 126.0
HKD1_k127_5176869_8 - - - - 0.000000001289 71.0
HKD1_k127_5176869_9 Transposase DDE domain - - - 0.00000001652 56.0
HKD1_k127_5185165_0 Bacterial extracellular solute-binding proteins, family 5 Middle K12368 - - 2.519e-265 826.0
HKD1_k127_5185165_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.241e-255 798.0
HKD1_k127_5185165_10 Epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000427 287.0
HKD1_k127_5185165_11 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000001241 229.0
HKD1_k127_5185165_12 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000001101 216.0
HKD1_k127_5185165_13 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.00000000000000000000000000000000000000000000004461 184.0
HKD1_k127_5185165_14 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000001891 180.0
HKD1_k127_5185165_15 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.00000000000000000000000000453 117.0
HKD1_k127_5185165_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K12369,K19227 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 500.0
HKD1_k127_5185165_3 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 490.0
HKD1_k127_5185165_4 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF K12371,K15583 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015232,GO:0015886,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 456.0
HKD1_k127_5185165_5 the ABC transporter K12372,K19230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 436.0
HKD1_k127_5185165_6 N-terminal TM domain of oligopeptide transport permease C K12370 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 417.0
HKD1_k127_5185165_7 PFAM Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 394.0
HKD1_k127_5185165_8 Glycosyltransferase like family K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 335.0
HKD1_k127_5185165_9 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 305.0
HKD1_k127_5236958_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 2.892e-213 672.0
HKD1_k127_5236958_1 Glycosyl transferase 4-like domain K03208 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004644 274.0
HKD1_k127_5236958_2 Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) K02851 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008963,GO:0009058,GO:0009059,GO:0009103,GO:0009246,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046378,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000001142 258.0
HKD1_k127_5236958_3 Putative restriction endonuclease - - - 0.0000000000000000003141 91.0
HKD1_k127_5236958_4 nuclease activity - - - 0.000000000889 63.0
HKD1_k127_5236958_5 Putative restriction endonuclease - - - 0.00000003371 58.0
HKD1_k127_5237625_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 585.0
HKD1_k127_5237625_1 With LivFGHM is involved in the high affinity leucine transport K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000828 471.0
HKD1_k127_5237625_10 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535 - 3.6.3.6 0.000000000000000000000004493 104.0
HKD1_k127_5237625_11 DDE superfamily endonuclease - - - 0.000000000000000005611 88.0
HKD1_k127_5237625_12 oxidase subunit K00425 - 1.10.3.14 0.00000000000004108 79.0
HKD1_k127_5237625_13 ATPase, P-type transporting, HAD superfamily, subfamily IC K01535 - 3.6.3.6 0.0000000001328 64.0
HKD1_k127_5237625_14 TIGRFAM cytochrome d oxidase, subunit II (cydB) K00426 - 1.10.3.14 0.000003578 49.0
HKD1_k127_5237625_2 PFAM cytochrome bd ubiquinol oxidase, subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 464.0
HKD1_k127_5237625_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 347.0
HKD1_k127_5237625_4 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000004105 228.0
HKD1_k127_5237625_5 - - - - 0.0000000000000000000000000000000000000000000000000000000005151 217.0
HKD1_k127_5237625_6 FimV N-terminal domain protein - - - 0.000000000000000000000000000000000000000000000000000000006095 211.0
HKD1_k127_5237625_7 YfdX protein - - - 0.000000000000000000000000000000000000000000000001381 191.0
HKD1_k127_5237625_8 Transposase DDE domain - - - 0.00000000000000000000000000000002975 131.0
HKD1_k127_5237625_9 Transposase domain (DUF772) - - - 0.0000000000000000000000000005989 120.0
HKD1_k127_5245404_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 290.0
HKD1_k127_5245404_1 Putative transposase, YhgA-like - - - 0.000000000000000000000000000000000000000000000000000001795 200.0
HKD1_k127_5245404_2 Phage integrase family - - - 0.00000000000000000000000000000000000000000001164 165.0
HKD1_k127_5245404_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000172 131.0
HKD1_k127_5245404_4 Phage integrase family - - - 0.0000000000000000000001664 104.0
HKD1_k127_5245404_5 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.0000000000000000003835 89.0
HKD1_k127_5245404_6 Phage integrase family - - - 0.000000000008185 66.0
HKD1_k127_5281083_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.0 1393.0
HKD1_k127_5281083_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1065.0
HKD1_k127_5281083_10 Protein of unknown function (DUF2939) - - - 0.00000002141 57.0
HKD1_k127_5281083_11 Protein of unknown function (DUF2939) - - - 0.0000008417 56.0
HKD1_k127_5281083_12 transposase activity - - - 0.0000009344 50.0
HKD1_k127_5281083_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 557.0
HKD1_k127_5281083_3 type I restriction modification DNA specificity domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 353.0
HKD1_k127_5281083_4 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.00000000000000000000000000000000000031 143.0
HKD1_k127_5281083_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000000000362 135.0
HKD1_k127_5281083_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000005588 113.0
HKD1_k127_5281083_8 ISXO2-like transposase domain - - - 0.000000000000000000000001732 105.0
HKD1_k127_5281083_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03425 GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000007942 59.0
HKD1_k127_5287262_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 444.0
HKD1_k127_5287262_1 Peptidase family M48 K03799 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 427.0
HKD1_k127_5287262_2 Zinc-ribbon containing domain - - - 0.000000000000000000000000000000000000001009 154.0
HKD1_k127_5288265_0 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 575.0
HKD1_k127_5288265_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008953 274.0
HKD1_k127_5288265_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000007694 239.0
HKD1_k127_5288265_3 Oxidoreductase FAD-binding domain K02823 - - 0.0000000000000000000000000000000000000000002645 166.0
HKD1_k127_5288265_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000002621 137.0
HKD1_k127_5288265_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000004279 103.0
HKD1_k127_5288265_6 TIGRFAM TonB K03832 - - 0.0000000000000000003344 89.0
HKD1_k127_5322023_0 signal transduction histidine kinase - - - 7.492e-212 683.0
HKD1_k127_5322023_1 Response regulator receiver K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 585.0
HKD1_k127_5322023_10 PFAM Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000008186 150.0
HKD1_k127_5322023_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 445.0
HKD1_k127_5322023_3 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 440.0
HKD1_k127_5322023_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 353.0
HKD1_k127_5322023_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 283.0
HKD1_k127_5322023_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000001283 265.0
HKD1_k127_5322023_7 PFAM Peptidoglycan-binding lysin domain - - - 0.0000000000000000000000000000000000000000000000000000004504 208.0
HKD1_k127_5322023_8 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000000000000000000000001374 195.0
HKD1_k127_5322023_9 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000888 156.0
HKD1_k127_5328828_0 heat shock protein 70 - - - 3.139e-250 784.0
HKD1_k127_5328828_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 481.0
HKD1_k127_5328828_2 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 302.0
HKD1_k127_5328828_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000002472 187.0
HKD1_k127_5328828_4 permease K00427,K03303 - - 0.00000000000000000000000000000000000000004818 156.0
HKD1_k127_5328828_5 PFAM heat shock protein DnaJ - - - 0.00000000000000000000004846 102.0
HKD1_k127_5328828_6 L-lactate permease K02550,K03303 - - 0.00000000000000005817 81.0
HKD1_k127_5332068_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 423.0
HKD1_k127_5332068_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 319.0
HKD1_k127_5332068_2 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 301.0
HKD1_k127_5332068_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000002058 229.0
HKD1_k127_5336460_0 PFAM Transposase domain (DUF772) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 599.0
HKD1_k127_5336460_1 Transposase - - - 0.00007437 47.0
HKD1_k127_5374918_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 2.159e-196 626.0
HKD1_k127_5374918_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000002461 224.0
HKD1_k127_5374918_2 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.0000000000000000000000000000000000000000000000000007318 185.0
HKD1_k127_5374918_3 PFAM Plasmid maintenance system killer K07334 - - 0.00000000000000000000000000000000000000002667 153.0
HKD1_k127_5374918_4 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000002209 149.0
HKD1_k127_5374918_8 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.00000000005635 65.0
HKD1_k127_537810_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1174.0
HKD1_k127_537810_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.037e-294 908.0
HKD1_k127_537810_10 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000003724 183.0
HKD1_k127_537810_11 SURF1-like protein - - - 0.0000000000000000000000000000000000000000000000008141 184.0
HKD1_k127_537810_12 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000000000000002413 137.0
HKD1_k127_537810_13 signal sequence binding - - - 0.000000000000000000000000005047 118.0
HKD1_k127_537810_14 Protein of unknown function (DUF2909) - - - 0.00000000000001382 75.0
HKD1_k127_537810_15 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000008312 76.0
HKD1_k127_537810_2 alcohol dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 483.0
HKD1_k127_537810_3 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 430.0
HKD1_k127_537810_4 UbiA prenyltransferase family K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 381.0
HKD1_k127_537810_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 348.0
HKD1_k127_537810_6 dna polymerase III delta subunit K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 325.0
HKD1_k127_537810_7 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000003664 249.0
HKD1_k127_537810_8 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.0000000000000000000000000000000000000000000000000000005774 199.0
HKD1_k127_537810_9 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000003941 202.0
HKD1_k127_5415018_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.475e-260 807.0
HKD1_k127_5415018_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 537.0
HKD1_k127_5415018_2 Acid phosphatase homologues K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 499.0
HKD1_k127_5415018_3 Belongs to the citrate synthase family K01647,K01659 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0071704 2.3.3.1,2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 432.0
HKD1_k127_5415018_4 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 303.0
HKD1_k127_5415018_5 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000000000000000000000000000000004784 204.0
HKD1_k127_5418388_0 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 539.0
HKD1_k127_5418388_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 439.0
HKD1_k127_5418388_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 399.0
HKD1_k127_5439968_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 602.0
HKD1_k127_5439968_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 610.0
HKD1_k127_5439968_10 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000001144 118.0
HKD1_k127_5439968_11 mRNA binding K07339 - - 0.00000000000000000000000005832 108.0
HKD1_k127_5439968_12 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000001779 98.0
HKD1_k127_5439968_2 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 535.0
HKD1_k127_5439968_3 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 409.0
HKD1_k127_5439968_4 PFAM aminotransferase, class I K02225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 393.0
HKD1_k127_5439968_5 Major facilitator superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 389.0
HKD1_k127_5439968_6 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 373.0
HKD1_k127_5439968_7 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 359.0
HKD1_k127_5439968_8 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000007961 239.0
HKD1_k127_5439968_9 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001556 235.0
HKD1_k127_5452019_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.156e-236 735.0
HKD1_k127_5452019_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.261e-198 627.0
HKD1_k127_5452019_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 604.0
HKD1_k127_5452019_3 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 538.0
HKD1_k127_5452019_4 Belongs to the GARS family K01945 GO:0003674,GO:0003824,GO:0004637,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 317.0
HKD1_k127_5452019_5 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000001694 188.0
HKD1_k127_5465438_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 465.0
HKD1_k127_5465438_1 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007467 281.0
HKD1_k127_5465438_2 PIN domain - - - 0.0000000000000000000000000000000000000000000000000002667 189.0
HKD1_k127_5465438_3 COG4644 Transposase and inactivated derivatives TnpA family - - - 0.000000000000000000000000000001382 126.0
HKD1_k127_5465438_4 transposase activity - - - 0.000000001073 65.0
HKD1_k127_5534217_0 MacB-like periplasmic core domain K02004 - - 1.631e-204 666.0
HKD1_k127_5534217_1 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 592.0
HKD1_k127_5534217_10 - - - - 0.00000000004635 69.0
HKD1_k127_5534217_11 Helix-turn-helix domain - - - 0.00002283 49.0
HKD1_k127_5534217_12 KR domain - - - 0.00007283 48.0
HKD1_k127_5534217_13 - - - - 0.0006068 47.0
HKD1_k127_5534217_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 454.0
HKD1_k127_5534217_3 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 430.0
HKD1_k127_5534217_4 Flavodoxin-like fold K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 335.0
HKD1_k127_5534217_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005429 265.0
HKD1_k127_5534217_6 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000002092 220.0
HKD1_k127_5534217_7 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000002796 218.0
HKD1_k127_5534217_8 Ntpase (Nacht family) - - - 0.000000000000000000000000000000000000002712 149.0
HKD1_k127_5534217_9 Plasmid replication region DNA-binding N-term - - - 0.000000000000000000004717 105.0
HKD1_k127_554558_0 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 6.285e-284 878.0
HKD1_k127_554558_1 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01965 - 6.4.1.3 0.000000000000000000000000000000000000000000000000000000007165 200.0
HKD1_k127_554558_2 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.000000000000000000000001823 112.0
HKD1_k127_554558_3 COG1943 Transposase and inactivated derivatives - - - 0.00000000000000000001176 94.0
HKD1_k127_554558_4 COG1943 Transposase and inactivated derivatives - - - 0.000000004025 60.0
HKD1_k127_554558_5 NACHT domain - - - 0.000004676 56.0
HKD1_k127_554558_6 Nacht domain - - - 0.0008573 46.0
HKD1_k127_5560064_0 AAA-like domain - - - 0.0 1169.0
HKD1_k127_5560064_1 NurA - - - 1.404e-207 652.0
HKD1_k127_5560064_2 DNA methylase K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 522.0
HKD1_k127_5560064_3 SPTR Transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000007997 173.0
HKD1_k127_5560064_4 hmm pf02371 - - - 0.00000000000000000000000000000000000004597 145.0
HKD1_k127_5561214_0 recombinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 492.0
HKD1_k127_5561214_1 recombinase activity - - - 0.0000000000000000000000000000000000000000000000000000006021 197.0
HKD1_k127_5561214_2 recombinase activity - - - 0.0000000000000000000000000000000000003245 143.0
HKD1_k127_557686_0 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 2.292e-237 753.0
HKD1_k127_557686_1 MMPL family K18138,K18902 - - 0.00000000000000000000000000000000000000000000000000000008334 198.0
HKD1_k127_557686_2 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases K01153 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000002335 189.0
HKD1_k127_557686_3 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases K01153 - 3.1.21.3 0.00000000000000000000000000000000000000000004078 163.0
HKD1_k127_557686_4 efflux pump K03296 - - 0.0000000001513 63.0
HKD1_k127_557686_5 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.0005464 46.0
HKD1_k127_5588393_0 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001579 244.0
HKD1_k127_5588393_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000002356 234.0
HKD1_k127_5588393_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000291 220.0
HKD1_k127_5588393_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000002808 188.0
HKD1_k127_5588483_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0 1141.0
HKD1_k127_5588483_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 522.0
HKD1_k127_5588483_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 331.0
HKD1_k127_5588483_3 Protein of unknown function (DUF1614) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001466 269.0
HKD1_k127_5588483_4 ABC transporter K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000003543 234.0
HKD1_k127_5588483_5 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000001555 228.0
HKD1_k127_5588483_6 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0005322 47.0
HKD1_k127_5594680_0 Transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 597.0
HKD1_k127_5594680_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000008595 85.0
HKD1_k127_5594680_2 Homeodomain-like domain - - - 0.00000000000000001522 86.0
HKD1_k127_5617244_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 542.0
HKD1_k127_5617244_1 Biotin-lipoyl like K01993 - - 0.0004605 44.0
HKD1_k127_5631457_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 2.137e-201 630.0
HKD1_k127_5631457_1 TIGRFAM cytochrome c oxidase accessory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 612.0
HKD1_k127_5631457_2 PFAM Cytochrome C oxidase, monoheme subunit FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 392.0
HKD1_k127_5631457_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 363.0
HKD1_k127_5631457_5 Belongs to the BolA IbaG family - - - 0.00008055 46.0
HKD1_k127_5632182_0 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01965 - 6.4.1.3 2.601e-298 928.0
HKD1_k127_5632182_1 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 1.94e-293 906.0
HKD1_k127_5632182_2 PEP-CTERM system TPR-repeat lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 305.0
HKD1_k127_5632182_3 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000003214 221.0
HKD1_k127_5654456_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 6.424e-195 617.0
HKD1_k127_5654456_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 411.0
HKD1_k127_5654456_2 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000245 276.0
HKD1_k127_5654456_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000003501 244.0
HKD1_k127_5654456_4 integral membrane protein K02221 - - 0.0000000000000000000000000000000000000000000003084 173.0
HKD1_k127_5654456_5 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000001207 110.0
HKD1_k127_5688114_0 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 417.0
HKD1_k127_5688114_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 364.0
HKD1_k127_5688114_10 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000159 68.0
HKD1_k127_5688114_11 Transposase K07492 - - 0.0000004761 55.0
HKD1_k127_5688114_12 Transposase DDE domain K07492 - - 0.000002702 50.0
HKD1_k127_5688114_2 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 320.0
HKD1_k127_5688114_3 Tn3 transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007473 240.0
HKD1_k127_5688114_4 TrfA protein - - - 0.000000000000000000000000000000000000000000000000000000000000004086 228.0
HKD1_k127_5688114_5 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000004497 199.0
HKD1_k127_5688114_6 DsrE/DsrF-like family K06039 - - 0.000000000000000000000000000000000000001872 153.0
HKD1_k127_5688114_7 InterPro IPR009057 - - - 0.000000000000000000000000000000000000002782 152.0
HKD1_k127_5688114_8 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.00000000000000000000000006828 114.0
HKD1_k127_5688114_9 Tn3 transposase DDE domain - - - 0.000000000002126 73.0
HKD1_k127_5688205_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 3.487e-286 899.0
HKD1_k127_5688205_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 522.0
HKD1_k127_5688205_2 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 516.0
HKD1_k127_5688205_3 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 376.0
HKD1_k127_5688205_4 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 334.0
HKD1_k127_5688205_5 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000000000001775 226.0
HKD1_k127_5688205_6 DUF218 domain - - - 0.000000000000000000000005111 106.0
HKD1_k127_5688205_7 dehydratase - - - 0.0000000000000005404 82.0
HKD1_k127_5688205_8 PFAM glutaredoxin 2 - - - 0.00000000000002464 77.0
HKD1_k127_5688205_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000007797 73.0
HKD1_k127_5696313_0 Belongs to the NifD NifK NifE NifN family K02592 - - 0.0000000000000000000000000000000000000000000000000000002553 198.0
HKD1_k127_5696313_1 Pfam Dinitrogenase iron-molybdenum cofactor K02596 - - 0.00000000000000000000000000000000000000000000000000001905 193.0
HKD1_k127_5696313_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000004398 135.0
HKD1_k127_5696313_3 TIGRFAM ferredoxin III - - - 0.000000000000000000000000000000002147 131.0
HKD1_k127_5696313_4 TOBE domain - - - 0.0000000000000000000000000002836 118.0
HKD1_k127_5709729_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 517.0
HKD1_k127_5709729_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 389.0
HKD1_k127_5709729_2 Belongs to the SUA5 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 305.0
HKD1_k127_5709729_3 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005706 267.0
HKD1_k127_5709729_4 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000004149 238.0
HKD1_k127_5709729_5 YCII-related domain K09780 - - 0.00000000000000000000000000002266 117.0
HKD1_k127_5738557_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 6.933e-218 685.0
HKD1_k127_5738557_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 357.0
HKD1_k127_5738557_2 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 354.0
HKD1_k127_5738557_3 Circularly permuted ATP-grasp type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 347.0
HKD1_k127_5738557_4 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000005791 258.0
HKD1_k127_5738557_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000002255 126.0
HKD1_k127_5738557_6 - - - - 0.0000000000001539 71.0
HKD1_k127_5752057_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000002172 127.0
HKD1_k127_5752057_1 nitric oxide dioxygenase activity K17247 - - 0.0000000000000000000000000000081 130.0
HKD1_k127_5752057_2 Aldo/keto reductase family - - - 0.000000001435 59.0
HKD1_k127_5761067_0 Belongs to the HypD family K04654 - - 1.365e-194 611.0
HKD1_k127_5761067_1 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 469.0
HKD1_k127_5770249_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 5.816e-216 689.0
HKD1_k127_5770249_1 Polyphosphate kinase 2 (PPK2) - - - 6.189e-206 653.0
HKD1_k127_5770249_10 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000006103 106.0
HKD1_k127_5770249_11 - - - - 0.0000000000000000000002259 98.0
HKD1_k127_5770249_12 Putative Fe-S cluster - - - 0.00000000000000000001059 95.0
HKD1_k127_5770249_13 Protein of unknown function (DUF2442) - - - 0.000000000000000001184 86.0
HKD1_k127_5770249_14 Protein of unknown function (DUF2442) - - - 0.00000000000000002564 82.0
HKD1_k127_5770249_15 - - - - 0.000000000000002081 78.0
HKD1_k127_5770249_16 Hydrogenase formation hypA family K04654 - - 0.00000000000001759 73.0
HKD1_k127_5770249_17 serine acetyltransferase K00640 - 2.3.1.30 0.0000000000002546 72.0
HKD1_k127_5770249_18 Bacterial transferase hexapeptide (six repeats) K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 0.000000000002195 72.0
HKD1_k127_5770249_19 Transposase IS4 family - - - 0.00000000005706 64.0
HKD1_k127_5770249_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 543.0
HKD1_k127_5770249_20 transporter K05772 - - 0.0000001051 57.0
HKD1_k127_5770249_21 BolA family transcriptional regulator K09780 - - 0.0000005113 51.0
HKD1_k127_5770249_3 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 465.0
HKD1_k127_5770249_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 354.0
HKD1_k127_5770249_5 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000005014 251.0
HKD1_k127_5770249_6 PFAM Phosphoglycerate mutase K08296 - - 0.00000000000000000000000000000000000000000000000000000000001268 211.0
HKD1_k127_5770249_7 - - - - 0.0000000000000000000000000000000000000000000000000000000006269 211.0
HKD1_k127_5770249_8 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000001294 197.0
HKD1_k127_5770249_9 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000001191 152.0
HKD1_k127_5784013_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 352.0
HKD1_k127_5784013_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000006514 246.0
HKD1_k127_5784013_2 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000008226 212.0
HKD1_k127_5784013_3 TIR domain - - - 0.0000000000000000000000000000000000000000000000318 194.0
HKD1_k127_5784013_4 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000002721 164.0
HKD1_k127_5784013_5 PFAM YicC-like - - - 0.0000000000000000000000000000000000006447 145.0
HKD1_k127_5784013_7 COG3316 Transposase and inactivated derivatives - - - 0.0000000000000009428 78.0
HKD1_k127_5784013_8 COG3316 Transposase and inactivated derivatives - - - 0.0000009429 53.0
HKD1_k127_5784013_9 - - - - 0.00002144 51.0
HKD1_k127_5817536_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 1.753e-273 848.0
HKD1_k127_5817536_1 Asparagine synthase K01953 - 6.3.5.4 6.062e-233 735.0
HKD1_k127_5817536_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 604.0
HKD1_k127_5817536_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 518.0
HKD1_k127_5817536_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 465.0
HKD1_k127_5817536_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 352.0
HKD1_k127_5817536_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 312.0
HKD1_k127_5817536_7 TPR repeat - - - 0.00000000000000000000000000000000000000003198 160.0
HKD1_k127_5817536_8 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.0000000000000000000000000000000004468 137.0
HKD1_k127_5817536_9 CoA-binding protein K06929 - - 0.0006314 45.0
HKD1_k127_5839802_0 Putative transposase, YhgA-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 390.0
HKD1_k127_5839802_1 Protein of unknown function (DUF1269) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007161 243.0
HKD1_k127_5839802_2 YfdX protein - - - 0.0000000000000000000000000000000002506 140.0
HKD1_k127_5840776_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 3.842e-194 612.0
HKD1_k127_5840776_1 Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 500.0
HKD1_k127_5840776_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007048 272.0
HKD1_k127_5840776_3 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000105 199.0
HKD1_k127_5840776_4 Membrane fusogenic activity K09806 - - 0.00000000000000000000004721 101.0
HKD1_k127_5840776_5 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0001178 46.0
HKD1_k127_5842294_0 belongs to the CobB CobQ family K13788 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006091,GO:0006113,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008959,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015980,GO:0016053,GO:0016054,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017000,GO:0017001,GO:0017144,GO:0018130,GO:0019413,GO:0019427,GO:0019438,GO:0019541,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046394,GO:0046395,GO:0046459,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0070689,GO:0071616,GO:0071704,GO:0072329,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 2.3.1.8 3.088e-254 803.0
HKD1_k127_5842294_1 N-4 methylation of cytosine K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 398.0
HKD1_k127_5842294_2 Proton-conducting membrane transporter K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 291.0
HKD1_k127_5842294_3 Rubrerythrin - - - 0.000000000000000000000000000000000000000272 155.0
HKD1_k127_5842294_4 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000000000000000000000000001042 144.0
HKD1_k127_5842294_6 Transcriptional regulator - - - 0.0001473 54.0
HKD1_k127_5871598_0 DNA segregation ATPase FtsK SpoIIIE K03466 - - 1.119e-249 798.0
HKD1_k127_5871598_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001111 282.0
HKD1_k127_5871598_2 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000001045 269.0
HKD1_k127_5871598_3 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000002951 169.0
HKD1_k127_5871598_4 protein conserved in bacteria K09919 - - 0.00000000000000000000000000000000000001148 147.0
HKD1_k127_5871598_5 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000002018 121.0
HKD1_k127_5926746_0 PFAM von Willebrand factor type A - - - 0.0 1195.0
HKD1_k127_5926746_1 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 473.0
HKD1_k127_5926746_2 Putative transposase, YhgA-like - - - 0.000000000000000000000000000000000000000000000000000000000007908 213.0
HKD1_k127_5926746_3 NACHT domain - - - 0.00000000000000000000000000000000000000000000000000000006027 218.0
HKD1_k127_5926746_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.0000000000000000000000000000000000006837 143.0
HKD1_k127_5926746_5 Putative transposase, YhgA-like - - - 0.00000003111 57.0
HKD1_k127_5926746_6 Glycine-zipper domain - - - 0.0000001729 57.0
HKD1_k127_5926746_7 YXWGXW repeat (2 copies) - - - 0.00000752 52.0
HKD1_k127_5930624_0 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 384.0
HKD1_k127_5930624_1 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 291.0
HKD1_k127_5930624_2 subfamily IA, variant 3 K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 287.0
HKD1_k127_5930624_3 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.000000000000000000000000000000000000000001658 157.0
HKD1_k127_5930624_4 Hydrolase K08312 - - 0.000000000000000000000000000000009087 129.0
HKD1_k127_5930624_5 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.000000001865 59.0
HKD1_k127_5930624_6 Beta-L-arabinofuranosidase, GH127 - - - 0.00000546 48.0
HKD1_k127_5951675_0 Sulfatase K01130 - 3.1.6.1 0.0 1014.0
HKD1_k127_5951675_1 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.00000000003287 77.0
HKD1_k127_5980185_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2098.0
HKD1_k127_5980185_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.68e-225 709.0
HKD1_k127_5980185_2 helicase superfamily c-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 411.0
HKD1_k127_5980185_3 InterPro IPR008538 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 376.0
HKD1_k127_5988318_0 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.776e-242 761.0
HKD1_k127_5988318_1 plasmid maintenance K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003652 262.0
HKD1_k127_5988318_2 Rhodopirellula transposase DDE domain - - - 0.00000000000000000362 84.0
HKD1_k127_5988318_3 Replication initiator protein - - - 0.000000000000375 74.0
HKD1_k127_5988318_4 DDE superfamily endonuclease - - - 0.000004329 51.0
HKD1_k127_5998854_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 522.0
HKD1_k127_5998854_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000001042 104.0
HKD1_k127_6031534_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1181.0
HKD1_k127_6031534_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 561.0
HKD1_k127_6031534_2 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 349.0
HKD1_k127_6031534_3 Glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001044 242.0
HKD1_k127_6031534_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000009493 199.0
HKD1_k127_6031534_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000006164 104.0
HKD1_k127_6035696_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 459.0
HKD1_k127_6035696_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 445.0
HKD1_k127_6035696_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 436.0
HKD1_k127_6035696_3 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 350.0
HKD1_k127_6035696_4 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007083 265.0
HKD1_k127_6035696_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000002186 238.0
HKD1_k127_6035696_6 redox protein, regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000000000003572 213.0
HKD1_k127_6035696_7 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001864 205.0
HKD1_k127_6035696_8 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000002551 201.0
HKD1_k127_6038287_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 585.0
HKD1_k127_6038287_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 397.0
HKD1_k127_6050367_0 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.0 1905.0
HKD1_k127_6050367_1 trehalohydrolase K01236 - 3.2.1.141 9.783e-217 682.0
HKD1_k127_6050367_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 602.0
HKD1_k127_6050367_3 ion channel K05802 - - 0.000000000005902 78.0
HKD1_k127_6052766_0 Peptidase, M16 K06972 - - 0.0 1168.0
HKD1_k127_6052766_1 protein with protein kinase and helix-hairpin-helix DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 597.0
HKD1_k127_6052766_11 DoxX K15977 - - 0.000000000000000000000000000008855 124.0
HKD1_k127_6052766_12 Predicted integral membrane protein (DUF2282) - - - 0.0000000000000000000001753 99.0
HKD1_k127_6052766_13 IMP dehydrogenase activity K02000,K05847 - 3.6.3.32 0.000000000000000000001731 102.0
HKD1_k127_6052766_16 CRISPR-associated protein, Crm2 family K19076 - - 0.000001243 58.0
HKD1_k127_6052766_2 Histidine kinase K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 411.0
HKD1_k127_6052766_3 belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 347.0
HKD1_k127_6052766_4 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 341.0
HKD1_k127_6052766_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 328.0
HKD1_k127_6052766_6 Protein phosphatase 2C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001949 282.0
HKD1_k127_6052766_7 RAMP superfamily K09000 - - 0.000000000000000000000000000000000000000000000000000000000000000000001156 247.0
HKD1_k127_6052766_8 to be involved in DNA repair (RAMP superfamily) K19142 - - 0.000000000000000000000000000000000000000000000000000000000004234 218.0
HKD1_k127_6052766_9 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000000000000007161 179.0
HKD1_k127_6073384_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535 - 3.6.3.6 0.0 1109.0
HKD1_k127_6073384_1 manually curated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002822 269.0
HKD1_k127_6073384_2 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002417 258.0
HKD1_k127_6073384_3 Transposase - - - 0.000000000000000000000000000000000000000000004871 168.0
HKD1_k127_6073384_4 Transposase - - - 0.000000000000000000000000001095 114.0
HKD1_k127_6073384_5 PFAM Transglutaminase-like superfamily - - - 0.0000000000000007169 78.0
HKD1_k127_6073384_6 PFAM Transglutaminase-like superfamily - - - 0.000000001637 60.0
HKD1_k127_6100361_0 MMPL family - - - 0.0 1344.0
HKD1_k127_6100361_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1270.0
HKD1_k127_6100361_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1118.0
HKD1_k127_6100361_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.00000000000000000000000000000000000000000000006199 173.0
HKD1_k127_6136337_0 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 424.0
HKD1_k127_6136337_1 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.00000000000000000000000000000000000000000000000000000000003443 214.0
HKD1_k127_6136337_2 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000003094 182.0
HKD1_k127_6136337_3 Cobalt uptake substrate-specific transmembrane region - - - 0.000008183 49.0
HKD1_k127_6151560_0 Glycosyl transferase family 21 K11936 - - 0.0 1721.0
HKD1_k127_6151560_1 PFAM glycoside hydrolase family 39 - - - 3.309e-215 690.0
HKD1_k127_6151560_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001899 278.0
HKD1_k127_6151560_3 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000004698 237.0
HKD1_k127_6151560_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000007007 193.0
HKD1_k127_6151560_5 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02464,K02654 - 3.4.23.43 0.00000000000000000000000000000194 121.0
HKD1_k127_6151690_0 PFAM PspA IM30 family K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007839 249.0
HKD1_k127_6151690_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000000000001774 185.0
HKD1_k127_6151690_2 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000005162 126.0
HKD1_k127_6151690_3 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000001554 83.0
HKD1_k127_6151690_4 IMG reference gene - - - 0.0000000001112 64.0
HKD1_k127_6151690_5 IMG reference gene - - - 0.0000000005149 61.0
HKD1_k127_6180721_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 550.0
HKD1_k127_6180721_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 436.0
HKD1_k127_6180721_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 427.0
HKD1_k127_6180721_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 368.0
HKD1_k127_6180721_4 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 329.0
HKD1_k127_6180721_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000003732 218.0
HKD1_k127_6202491_0 COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 5.13e-235 734.0
HKD1_k127_6202491_1 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 586.0
HKD1_k127_6203442_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 438.0
HKD1_k127_6203442_1 glycosyl transferase group 1 K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 387.0
HKD1_k127_6203442_2 lipopolysaccharide heptosyltransferase I K02841 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 364.0
HKD1_k127_6203442_3 Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core K02848 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006981 278.0
HKD1_k127_6203442_4 Small Multidrug Resistance protein - - - 0.000000000000000000002091 102.0
HKD1_k127_6203442_5 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.000000006023 57.0
HKD1_k127_6203497_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 469.0
HKD1_k127_6203497_1 PFAM Lytic K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 420.0
HKD1_k127_6203497_2 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 332.0
HKD1_k127_6203497_3 COG0025 NhaP-type Na H and K H - - - 0.0000000000002768 75.0
HKD1_k127_6203497_4 NhaP-type Na H and K H - - - 0.000000000000808 74.0
HKD1_k127_6203497_5 COG0025 NhaP-type Na H and K H - - - 0.00000001061 59.0
HKD1_k127_6203497_6 Protein of unknown function (DUF1090) - - - 0.00000004035 61.0
HKD1_k127_6237649_0 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 360.0
HKD1_k127_6237649_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 289.0
HKD1_k127_6237649_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000006853 211.0
HKD1_k127_6237649_3 DDE superfamily endonuclease - - - 0.0000000000000000000001428 98.0
HKD1_k127_6258002_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 385.0
HKD1_k127_6258002_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001851 271.0
HKD1_k127_6258002_2 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004369 251.0
HKD1_k127_6258002_3 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000001556 194.0
HKD1_k127_6267833_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 353.0
HKD1_k127_6267833_1 Alpha/beta hydrolase family - - - 0.00000000000000000000002129 111.0
HKD1_k127_6267833_2 transcriptional regulator K07736 - - 0.000000000003803 73.0
HKD1_k127_6267833_3 PFAM RNA recognition motif - - - 0.000000003767 59.0
HKD1_k127_6276075_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 462.0
HKD1_k127_6276075_1 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 346.0
HKD1_k127_6276075_2 SMART AAA ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005184 279.0
HKD1_k127_6276075_3 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000009997 138.0
HKD1_k127_6276075_4 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.0000000000000000327 96.0
HKD1_k127_6298025_0 PFAM PrkA AAA K07180 - - 0.0 1107.0
HKD1_k127_6298025_1 SpoVR family K06415 - - 3.745e-263 817.0
HKD1_k127_6298025_10 Domain of unknown function (DUF4389) - - - 0.000000000000000000000004903 106.0
HKD1_k127_6298025_11 Protein of unknown function (DUF3301) - - - 0.0000000000000000000597 93.0
HKD1_k127_6298025_12 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000129 59.0
HKD1_k127_6298025_13 - - - - 0.000003528 56.0
HKD1_k127_6298025_14 - K07484 - - 0.0001086 45.0
HKD1_k127_6298025_2 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 577.0
HKD1_k127_6298025_3 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 468.0
HKD1_k127_6298025_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 417.0
HKD1_k127_6298025_5 Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus K07261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005517 248.0
HKD1_k127_6298025_6 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000203 215.0
HKD1_k127_6298025_7 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000003932 177.0
HKD1_k127_6298025_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000005962 134.0
HKD1_k127_6298025_9 Domain of unknown function DUF123 - - - 0.0000000000000000000000000002679 123.0
HKD1_k127_6300647_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 512.0
HKD1_k127_6300647_1 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 362.0
HKD1_k127_6300647_2 Alkyl hydroperoxide reductase subunit C K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 338.0
HKD1_k127_6300647_3 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 322.0
HKD1_k127_6300647_4 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000001641 165.0
HKD1_k127_6333966_0 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 355.0
HKD1_k127_6333966_1 Type 1 fimbriae regulatory protein K07357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000288 284.0
HKD1_k127_6333966_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002263 227.0
HKD1_k127_6333966_3 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000001784 216.0
HKD1_k127_6333966_4 NERD domain protein - - - 0.000000000000000000000000000000000000000001196 166.0
HKD1_k127_6333966_5 Protein of unknown function (DUF1778) - - - 0.00000000000000000000000000000000002051 137.0
HKD1_k127_6333966_6 PFAM Transposase, IS4-like - - - 0.0000000000000000000000000002777 115.0
HKD1_k127_6333966_7 - - - - 0.0000001901 54.0
HKD1_k127_6379587_0 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 581.0
HKD1_k127_6379587_1 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000005298 263.0
HKD1_k127_6379587_2 Lytic transglycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001314 249.0
HKD1_k127_6379587_3 PFAM AIG2-like - - - 0.00000000000000000000000000002692 121.0
HKD1_k127_6379587_4 COG1126 ABC-type polar amino acid transport system, ATPase component K02028,K09972 - 3.6.3.21 0.00000000000000007479 79.0
HKD1_k127_6398249_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 6.921e-280 879.0
HKD1_k127_6398249_1 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 342.0
HKD1_k127_6398249_10 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000001226 97.0
HKD1_k127_6398249_11 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000005009 93.0
HKD1_k127_6398249_12 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595,K02191 - 2.1.1.132,2.1.1.196 0.0000000000000001585 80.0
HKD1_k127_6398249_13 Thiamine biosynthesis protein K15598 - - 0.000000001038 60.0
HKD1_k127_6398249_2 Precorrin-4 C(11)-methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 339.0
HKD1_k127_6398249_3 O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000005879 266.0
HKD1_k127_6398249_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000001238 237.0
HKD1_k127_6398249_5 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000004192 198.0
HKD1_k127_6398249_6 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000004945 194.0
HKD1_k127_6398249_7 PFAM YicC-like family, N-terminal region - - - 0.00000000000000000000000000000000000000000003506 162.0
HKD1_k127_6398249_8 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000005509 123.0
HKD1_k127_6398249_9 PFAM TENA THI-4 PQQC family K03707 - 3.5.99.2 0.0000000000000000000000000008355 115.0
HKD1_k127_6402535_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1193.0
HKD1_k127_6402535_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.217e-228 711.0
HKD1_k127_6402535_10 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000003666 221.0
HKD1_k127_6402535_11 Involved in the binding of tRNA to the ribosomes K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000004821 198.0
HKD1_k127_6402535_12 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000003358 164.0
HKD1_k127_6402535_13 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000646 163.0
HKD1_k127_6402535_14 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000002229 160.0
HKD1_k127_6402535_15 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000006257 131.0
HKD1_k127_6402535_16 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000005821 127.0
HKD1_k127_6402535_17 Cupredoxin-like domain K02275 - 1.9.3.1 0.000000000000000000000000000001853 124.0
HKD1_k127_6402535_18 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000002958 110.0
HKD1_k127_6402535_19 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000001213 79.0
HKD1_k127_6402535_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 459.0
HKD1_k127_6402535_20 Metallophosphoesterase - - - 0.00000006263 54.0
HKD1_k127_6402535_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 359.0
HKD1_k127_6402535_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 322.0
HKD1_k127_6402535_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 302.0
HKD1_k127_6402535_6 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000003984 255.0
HKD1_k127_6402535_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005644 242.0
HKD1_k127_6402535_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000001916 238.0
HKD1_k127_6402535_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000004742 233.0
HKD1_k127_6412277_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 4.286e-317 987.0
HKD1_k127_6412277_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 486.0
HKD1_k127_6412277_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 424.0
HKD1_k127_6412277_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 369.0
HKD1_k127_6412277_4 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 347.0
HKD1_k127_6412277_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 302.0
HKD1_k127_6412277_6 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000482 278.0
HKD1_k127_6412277_7 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006234 274.0
HKD1_k127_6412277_8 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.000000000000000000000000000000000000000000000000003652 185.0
HKD1_k127_6412638_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 3.913e-197 622.0
HKD1_k127_6412638_1 Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 507.0
HKD1_k127_6412638_11 - - - - 0.0009726 42.0
HKD1_k127_6412638_2 PFAM integrase K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 338.0
HKD1_k127_6412638_3 Phage plasmid primase, P4 K06919 - - 0.00000000000000000000000000000000000000000000000000000000000003244 231.0
HKD1_k127_6412638_4 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000004829 151.0
HKD1_k127_6412638_5 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000003265 138.0
HKD1_k127_6412638_6 COG3209 Rhs family protein - - - 0.000000000000000000000000008184 113.0
HKD1_k127_6412638_7 PFAM transposase IS3 IS911 family protein - - - 0.00000000000000000000000006113 109.0
HKD1_k127_6412638_8 Putative restriction endonuclease - - - 0.00000000000000000006189 99.0
HKD1_k127_6412638_9 - - - - 0.000000000000135 73.0
HKD1_k127_6429574_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 550.0
HKD1_k127_6429574_1 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001963 278.0
HKD1_k127_6429574_2 Involved in initiation control of chromosome replication - - - 0.000000000000000000000000000000000000000000000000000001936 199.0
HKD1_k127_6429574_3 lyase activity - - - 0.000000000000000000000000000000000000000000000000000002409 197.0
HKD1_k127_6429574_4 Cupredoxin-like domain - - - 0.00000000000000000000000000005334 119.0
HKD1_k127_6429574_5 - - - - 0.000000000000000005823 88.0
HKD1_k127_6440946_0 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000854 372.0
HKD1_k127_6440946_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000002485 153.0
HKD1_k127_6440946_2 COGs COG3316 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000005531 126.0
HKD1_k127_6440946_3 - - - - 0.00000000000000000000000000001112 122.0
HKD1_k127_6440946_4 recombinase XerD K04763 - - 0.000000003186 63.0
HKD1_k127_6440946_5 Transposase and inactivated derivatives K07498 - - 0.0000002048 57.0
HKD1_k127_6440946_6 COG3316 Transposase and inactivated derivatives - - - 0.00004626 46.0
HKD1_k127_6473328_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 591.0
HKD1_k127_6473328_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 335.0
HKD1_k127_6473328_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 323.0
HKD1_k127_6473328_3 protein involved in formation of curli polymers - - - 0.00000000000000000000000000000000000000000000000000000000000001209 224.0
HKD1_k127_6473328_4 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.00000000000000000000000000000000000000000000000000001964 191.0
HKD1_k127_6473328_5 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000005523 111.0
HKD1_k127_6473405_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0 1140.0
HKD1_k127_6473405_1 AMP-binding enzyme C-terminal domain - - - 2.8e-228 717.0
HKD1_k127_6473405_2 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 466.0
HKD1_k127_6473405_3 Putative peptidoglycan binding domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 450.0
HKD1_k127_6473405_4 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005968 417.0
HKD1_k127_6473405_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 264.0
HKD1_k127_6473405_6 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003199 264.0
HKD1_k127_6473405_7 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000629 264.0
HKD1_k127_6473405_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001186 247.0
HKD1_k127_6485090_0 Glycosyltransferase like family 2 - - - 3.05e-231 725.0
HKD1_k127_6485090_1 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 571.0
HKD1_k127_6485090_2 HpcH/HpaI aldolase/citrate lyase family K08691 - 4.1.3.24,4.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 445.0
HKD1_k127_6485090_3 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 431.0
HKD1_k127_6485090_4 Catalyzes the conversion of chorismate to isochorismate K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 336.0
HKD1_k127_6485090_5 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000001324 252.0
HKD1_k127_6485090_6 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002116 244.0
HKD1_k127_6496615_0 Belongs to the CarB family K01955 - 6.3.5.5 2.775e-213 666.0
HKD1_k127_6496615_1 Belongs to the CarA family K01956 GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 571.0
HKD1_k127_6496615_2 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009791 376.0
HKD1_k127_6496615_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 366.0
HKD1_k127_6496615_4 ATPases associated with a variety of cellular activities K02074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 334.0
HKD1_k127_6496615_5 PFAM periplasmic solute binding protein K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005968 323.0
HKD1_k127_6496615_6 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 289.0
HKD1_k127_6496615_7 PFAM peptidase S11, D-alanyl-D-alanine carboxypeptidase K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000001131 215.0
HKD1_k127_6496615_8 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000001507 200.0
HKD1_k127_6496615_9 dNA-binding protein K03746 - - 0.00000000000000001258 86.0
HKD1_k127_6499095_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 9.801e-289 910.0
HKD1_k127_6499095_1 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 287.0
HKD1_k127_6509703_0 Periplasmic binding protein domain K01999,K11959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 613.0
HKD1_k127_6509703_1 branched-chain amino acid transport system, permease component K11961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 552.0
HKD1_k127_6509703_2 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 546.0
HKD1_k127_6509703_3 pfam abc K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 373.0
HKD1_k127_6509703_4 ABC transporter - - - 0.000000000000000000000000000000000000000000392 160.0
HKD1_k127_6518115_0 Glycosyl transferases group 1 - - - 1.27e-244 778.0
HKD1_k127_6518115_1 Carboxyl transferase domain - - - 1.268e-241 755.0
HKD1_k127_6518115_10 PFAM GtrA family protein - - - 0.0000000000000000003429 92.0
HKD1_k127_6518115_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 469.0
HKD1_k127_6518115_3 PFAM Glycosyl transferase, family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 439.0
HKD1_k127_6518115_4 malonyl CoA-acyl carrier protein transacylase K00645,K13935 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 357.0
HKD1_k127_6518115_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000004383 246.0
HKD1_k127_6518115_6 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000004264 234.0
HKD1_k127_6518115_7 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000004437 194.0
HKD1_k127_6518115_8 Biotin-requiring enzyme - - - 0.0000000000000000000000003768 109.0
HKD1_k127_6518115_9 Glycosyl transferase family 2 - - - 0.0000000000000000000008028 96.0
HKD1_k127_6534271_0 type III restriction protein res subunit K01153 - 3.1.21.3 0.0 1146.0
HKD1_k127_6534271_1 N-6 DNA methylase K03427 - 2.1.1.72 2.631e-301 929.0
HKD1_k127_6534271_10 Nucleotidyltransferase domain - - - 0.00000000000000005529 86.0
HKD1_k127_6534271_11 Protein of unknown function DUF86 K07075 - - 0.0000000000002669 75.0
HKD1_k127_6534271_12 mercury ion transmembrane transporter activity K07213 - - 0.000000002223 60.0
HKD1_k127_6534271_13 transposase or invertase - - - 0.00002038 50.0
HKD1_k127_6534271_2 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 441.0
HKD1_k127_6534271_3 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002282 233.0
HKD1_k127_6534271_4 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000001664 239.0
HKD1_k127_6534271_5 alpha amylase catalytic K05343 - 3.2.1.1,5.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000005258 227.0
HKD1_k127_6534271_6 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000000006332 141.0
HKD1_k127_6534271_7 Antitoxin ParD - - - 0.000000000000000000000000001173 113.0
HKD1_k127_6534271_8 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.000000000000000000000002484 111.0
HKD1_k127_6534271_9 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000005534 86.0
HKD1_k127_6541243_0 Transport of potassium into the cell K03549 - - 1.313e-224 713.0
HKD1_k127_6541243_1 Acyl-CoA synthetase (NDP forming) K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 428.0
HKD1_k127_6541243_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 374.0
HKD1_k127_6541243_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000007125 236.0
HKD1_k127_6541243_4 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000000003059 190.0
HKD1_k127_6541243_5 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000000000005519 151.0
HKD1_k127_6541243_6 - - - - 0.00000000000000000000000008651 113.0
HKD1_k127_6541243_7 - - - - 0.000000005066 61.0
HKD1_k127_6546074_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00244 - 1.3.5.4 0.0 1045.0
HKD1_k127_6546074_1 GTP-binding protein TypA K06207 - - 5.041e-317 979.0
HKD1_k127_6546074_10 fumarate reductase respiratory complex transmembrane subunit K00246 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 326.0
HKD1_k127_6546074_11 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000005889 211.0
HKD1_k127_6546074_12 Staphylococcal nuclease homologues - - - 0.00000000000000000000000000000000000008553 149.0
HKD1_k127_6546074_13 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000000009313 153.0
HKD1_k127_6546074_14 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000003066 145.0
HKD1_k127_6546074_16 transposase activity - - - 0.00008172 47.0
HKD1_k127_6546074_2 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K17686 - 3.6.3.54 8.489e-274 860.0
HKD1_k127_6546074_3 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 3.27e-265 826.0
HKD1_k127_6546074_4 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.456e-206 648.0
HKD1_k127_6546074_5 TIGRFAM Succinate dehydrogenase fumarate reductase iron-sulphur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 403.0
HKD1_k127_6546074_6 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 405.0
HKD1_k127_6546074_7 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 371.0
HKD1_k127_6546074_8 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 365.0
HKD1_k127_6546074_9 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 337.0
HKD1_k127_654988_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 2.618e-203 641.0
HKD1_k127_654988_1 FtsX-like permease family K02004 - - 3.53e-200 627.0
HKD1_k127_654988_2 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 503.0
HKD1_k127_654988_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 380.0
HKD1_k127_654988_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 370.0
HKD1_k127_654988_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000004799 255.0
HKD1_k127_654988_6 Transposase - - - 0.000000000000000000000000000000002514 135.0
HKD1_k127_654988_7 LTXXQ motif family protein - - - 0.00000000000000000135 91.0
HKD1_k127_655423_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 511.0
HKD1_k127_655423_1 Glutamate synthase K00266 GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000002948 192.0
HKD1_k127_655423_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000002126 175.0
HKD1_k127_655423_3 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000004623 169.0
HKD1_k127_655423_4 Belongs to the Nudix hydrolase family K01518 - 3.6.1.17 0.00000000000000000000000000000000000000000001906 165.0
HKD1_k127_6560968_0 alpha amylase catalytic K05343 - 3.2.1.1,5.4.99.16 0.0 1292.0
HKD1_k127_6560968_1 PFAM DNA RNA helicase, C-terminal - - - 4.326e-250 792.0
HKD1_k127_6560968_10 - - - - 0.0000000000000000721 82.0
HKD1_k127_6560968_11 Belongs to the glycosyl hydrolase 31 family K01187,K01811 - 3.2.1.177,3.2.1.20 0.000000000006256 69.0
HKD1_k127_6560968_12 Protein of unknown function (DUF3096) - - - 0.00000004533 55.0
HKD1_k127_6560968_13 - - - - 0.00001675 50.0
HKD1_k127_6560968_2 Protein of unknown function (DUF1156) K07445 - - 1.854e-224 704.0
HKD1_k127_6560968_3 Protein of unknown function (DUF499) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003458 282.0
HKD1_k127_6560968_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000001383 224.0
HKD1_k127_6560968_5 - - - - 0.0000000000000000000000000000000000000000000000000001094 196.0
HKD1_k127_6560968_6 - - - - 0.00000000000000000000000000004154 118.0
HKD1_k127_6560968_7 PIN domain - - - 0.00000000000000000000000000004849 121.0
HKD1_k127_6560968_8 DNA methylAse - - - 0.000000000000000000000003024 106.0
HKD1_k127_6560968_9 - - - - 0.000000000000000003588 85.0
HKD1_k127_6565542_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 4.872e-196 629.0
HKD1_k127_6565542_1 V-type proton ATPase subunit E K02121 - - 0.00000000000000000000000000000000000000000000000000000003857 203.0
HKD1_k127_6565542_2 ATP synthase subunit C K02124 - - 0.0000000000000000000000000000000000000000000002747 171.0
HKD1_k127_6565542_3 ATP synthase (C/AC39) subunit K02119 - - 0.0000000000000000000000000000000000000000009035 162.0
HKD1_k127_6565542_4 Produces ATP from ADP in the presence of a proton gradient across the membrane - - - 0.00000000000000000000000000001192 121.0
HKD1_k127_6565542_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0001071 44.0
HKD1_k127_6576486_0 Ferrous iron transport protein B K04759 - - 4.489e-306 957.0
HKD1_k127_6576486_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595,K02191 - 2.1.1.132,2.1.1.196 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 378.0
HKD1_k127_6576486_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 311.0
HKD1_k127_6576486_3 PFAM cobalamin (vitamin B12) biosynthesis CbiX K03795 - 4.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000009936 262.0
HKD1_k127_6576486_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000001574 231.0
HKD1_k127_6576486_5 Alkyl hydroperoxide reductase Thiol specific antioxidant K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000001052 169.0
HKD1_k127_6576486_6 Desuccinylase aspartoacylase K06987 - - 0.00000000000000000000000000000000005102 138.0
HKD1_k127_6576486_7 PFAM Ferrous iron transporter, FeoA subunit K04758 - - 0.0000000000000000000000002116 107.0
HKD1_k127_6576486_8 FeoC like transcriptional regulator - - - 0.000000000002052 70.0
HKD1_k127_6589573_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 2.032e-201 639.0
HKD1_k127_6589573_1 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 489.0
HKD1_k127_6589573_10 Planctomycete cytochrome C - - - 0.0000000000000000000000000003797 117.0
HKD1_k127_6589573_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 324.0
HKD1_k127_6589573_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 291.0
HKD1_k127_6589573_4 Cytochrome C1 family K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 288.0
HKD1_k127_6589573_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002145 272.0
HKD1_k127_6589573_6 Stringent starvation protein B K03600 GO:0000502,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0009376,GO:0009893,GO:0009894,GO:0009896,GO:0010604,GO:0019222,GO:0019899,GO:0031597,GO:0032781,GO:0032991,GO:0042176,GO:0042802,GO:0042803,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045732,GO:0046983,GO:0048518,GO:0050789,GO:0050790,GO:0051117,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:1901363,GO:1902494,GO:1904949,GO:1905368,GO:1905369,GO:1990904 - 0.0000000000000000000000000000000000000000002389 162.0
HKD1_k127_6589573_7 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000000003663 163.0
HKD1_k127_6589573_8 PFAM transport-associated - - - 0.000000000000000000000000000000000000002927 156.0
HKD1_k127_6589573_9 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000005066 125.0
HKD1_k127_6672698_0 response regulator receiver K02487,K06596 - - 2.794e-226 754.0
HKD1_k127_6672698_1 chemotaxis K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 514.0
HKD1_k127_6672698_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 434.0
HKD1_k127_6672698_3 response regulator K02657 - - 0.000000000000000000000000000000000000000000000000003312 184.0
HKD1_k127_6672698_4 chemotaxis signal transduction protein K02659 - - 0.0000000000000000000000000001269 121.0
HKD1_k127_6688554_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1269.0
HKD1_k127_6688554_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1122.0
HKD1_k127_6688554_2 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 481.0
HKD1_k127_6688554_3 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 344.0
HKD1_k127_6688554_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000001574 103.0
HKD1_k127_6713408_0 FES K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 437.0
HKD1_k127_6713408_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 421.0
HKD1_k127_6713408_2 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.0000000000000000000000000000000000000000000000000489 180.0
HKD1_k127_6713408_3 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000006041 155.0
HKD1_k127_6713408_4 ADP-glyceromanno-heptose 6-epimerase activity K00311 - 1.5.5.1 0.000000000000000000000000634 108.0
HKD1_k127_6730066_0 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 344.0
HKD1_k127_6730066_1 thiamine biosynthesis protein ThiS K03154 - - 0.000002443 50.0
HKD1_k127_6743732_0 transport system, permease component K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 533.0
HKD1_k127_6743732_1 ATPases associated with a variety of cellular activities K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 395.0
HKD1_k127_6743732_2 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 368.0
HKD1_k127_6743732_3 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 323.0
HKD1_k127_6743732_4 Phospholipid-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008382 272.0
HKD1_k127_6743732_5 - - - - 0.0000000000000000000005676 98.0
HKD1_k127_6743732_6 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 0.0004132 43.0
HKD1_k127_6751575_0 Proton-conducting membrane transporter - - - 2.756e-249 779.0
HKD1_k127_6751575_1 NADH-ubiquinone oxidoreductase chain 49kDa - - - 1.382e-231 725.0
HKD1_k127_6751575_2 Proton-conducting membrane transporter K12141 - - 1.055e-221 700.0
HKD1_k127_6751575_3 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 436.0
HKD1_k127_6751575_4 Zinc finger SWIM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 396.0
HKD1_k127_6751575_5 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 300.0
HKD1_k127_6751575_6 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 280.0
HKD1_k127_6773663_0 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 524.0
HKD1_k127_6773663_1 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 509.0
HKD1_k127_6773663_2 TIGRFAM sulfate ABC transporter, inner membrane subunit CysT K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 305.0
HKD1_k127_6773663_3 AMP-dependent synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 294.0
HKD1_k127_6773663_4 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
HKD1_k127_6852637_0 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 387.0
HKD1_k127_6856001_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1651.0
HKD1_k127_6856001_1 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 1.38e-245 779.0
HKD1_k127_6856001_10 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000000002128 183.0
HKD1_k127_6856001_11 COG0754 Glutathionylspermidine synthase K01460 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008884,GO:0008885,GO:0016787,GO:0016810,GO:0016811,GO:0016874,GO:0016879,GO:0016880,GO:0044424,GO:0044444,GO:0044464 3.5.1.78,6.3.1.8 0.00000000000000000000000000000004976 132.0
HKD1_k127_6856001_12 Cytochrome C' - - - 0.0000000000000000000000000000001134 130.0
HKD1_k127_6856001_13 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.000000005482 62.0
HKD1_k127_6856001_2 protein conserved in bacteria K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 589.0
HKD1_k127_6856001_3 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 472.0
HKD1_k127_6856001_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 461.0
HKD1_k127_6856001_5 malic enzyme K00029 - 1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 446.0
HKD1_k127_6856001_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 361.0
HKD1_k127_6856001_7 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 322.0
HKD1_k127_6856001_8 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000244 268.0
HKD1_k127_6856001_9 Copper resistance protein D - - - 0.00000000000000000000000000000000000000000000000000000001517 201.0
HKD1_k127_6888399_0 Phage tail sheath protein K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 440.0
HKD1_k127_6888399_1 Phage tail sheath C-terminal domain K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 348.0
HKD1_k127_6888399_10 - - - - 0.00000000000000009258 81.0
HKD1_k127_6888399_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002613 255.0
HKD1_k127_6888399_3 PFAM T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006977 239.0
HKD1_k127_6888399_4 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007211 243.0
HKD1_k127_6888399_5 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000000000000000000000000000000000001282 233.0
HKD1_k127_6888399_6 - - - - 0.0000000000000000000000000000000000000000000000000000024 192.0
HKD1_k127_6888399_7 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000001353 145.0
HKD1_k127_6888399_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000008833 144.0
HKD1_k127_6888399_9 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.000000000000000000000000000001235 123.0
HKD1_k127_6906426_0 extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 294.0
HKD1_k127_6906426_2 ABC-type Fe3 transport system permease component K02011 - - 0.0001462 53.0
HKD1_k127_6906856_0 SNF2 family N-terminal domain K03580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 618.0
HKD1_k127_6906856_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 306.0
HKD1_k127_6906856_2 helicase superfamily c-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 310.0
HKD1_k127_6913640_0 PFAM NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 6.942e-312 969.0
HKD1_k127_6913640_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 490.0
HKD1_k127_6913640_10 - - - - 0.000000000000005528 82.0
HKD1_k127_6913640_11 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000004085 55.0
HKD1_k127_6913640_2 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 443.0
HKD1_k127_6913640_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005273 281.0
HKD1_k127_6913640_4 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001326 261.0
HKD1_k127_6913640_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000002304 229.0
HKD1_k127_6913640_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000003261 217.0
HKD1_k127_6913640_7 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000463 177.0
HKD1_k127_6913640_8 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000001224 175.0
HKD1_k127_6913640_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000159 102.0
HKD1_k127_6924509_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1088.0
HKD1_k127_6924509_1 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 393.0
HKD1_k127_6933072_1 Transposase DDE domain - - - 0.000005586 59.0
HKD1_k127_699272_0 Bacterial extracellular solute-binding protein K10236 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 592.0
HKD1_k127_699272_1 phosphorelay signal transduction system K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 523.0
HKD1_k127_699272_10 type I restriction modification DNA specificity domain - - - 0.00004165 46.0
HKD1_k127_699272_2 TOBE domain K05816,K10111,K10112 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 454.0
HKD1_k127_699272_3 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008762 443.0
HKD1_k127_699272_4 Binding-protein-dependent transport system inner membrane component K10238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 406.0
HKD1_k127_699272_5 - K07498 - - 0.000000000000000000000000000000000000000000000005759 179.0
HKD1_k127_699272_6 type I restriction modification DNA specificity domain - - - 0.0000000000000000000000000000000000000001593 156.0
HKD1_k127_699272_7 Plasmid replication region DNA-binding N-term - - - 0.000000000000000000005437 105.0
HKD1_k127_699272_8 Helix-turn-helix domain of transposase family ISL3 - - - 0.0000000003295 63.0
HKD1_k127_699272_9 Phage terminase, small subunit - - - 0.00002753 52.0
HKD1_k127_7022489_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1965.0
HKD1_k127_7022489_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002974 277.0
HKD1_k127_7022489_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001739 261.0
HKD1_k127_7022489_3 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000976 256.0
HKD1_k127_7022489_4 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000000000000000000000000009875 212.0
HKD1_k127_7022489_5 PFAM Type IV pilus assembly PilZ K02676 - - 0.000000000000000000000000000000000000001381 150.0
HKD1_k127_7030695_0 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 597.0
HKD1_k127_7030695_1 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 406.0
HKD1_k127_7030695_2 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 365.0
HKD1_k127_7030695_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 295.0
HKD1_k127_7030695_4 Transferase hexapeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004821 246.0
HKD1_k127_7030695_5 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000006099 186.0
HKD1_k127_7030695_6 - - - - 0.0000000000000009978 77.0
HKD1_k127_7030695_7 chaperone-mediated protein folding K02660,K03466,K07474,K19175 - - 0.0001534 54.0
HKD1_k127_7039554_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1016.0
HKD1_k127_7039554_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.945e-267 839.0
HKD1_k127_7039554_2 AAA domain - - - 7.02e-206 683.0
HKD1_k127_7039554_3 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 608.0
HKD1_k127_7039554_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 596.0
HKD1_k127_7039554_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 562.0
HKD1_k127_7039554_6 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 432.0
HKD1_k127_7039554_7 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000001838 248.0
HKD1_k127_7039554_8 NACHT domain - - - 0.00000000000000000000000000000000000000000000000000009376 202.0
HKD1_k127_7047334_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.835e-234 732.0
HKD1_k127_7047334_1 Fis Family K02584 - - 1.604e-222 700.0
HKD1_k127_7047334_10 PFAM ATP-binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 413.0
HKD1_k127_7047334_11 Transaldolase/Fructose-6-phosphate aldolase K00616,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 397.0
HKD1_k127_7047334_12 AAA domain K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 380.0
HKD1_k127_7047334_13 SIR2-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 362.0
HKD1_k127_7047334_14 amino acid transport system, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 354.0
HKD1_k127_7047334_15 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 311.0
HKD1_k127_7047334_16 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 293.0
HKD1_k127_7047334_17 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007626 273.0
HKD1_k127_7047334_18 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000001355 188.0
HKD1_k127_7047334_19 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000005523 190.0
HKD1_k127_7047334_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 613.0
HKD1_k127_7047334_20 PFAM NifZ K02597 - - 0.0000000000000000000000000000000000000000002858 161.0
HKD1_k127_7047334_21 epsilon subunit K02114 - - 0.000000000000000000000000000000000000000001159 159.0
HKD1_k127_7047334_22 Pfam:DUF461 K09796 - - 0.00000000000000000000000000000000003764 140.0
HKD1_k127_7047334_23 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000004444 122.0
HKD1_k127_7047334_24 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000002164 117.0
HKD1_k127_7047334_25 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000000000000000000000001251 109.0
HKD1_k127_7047334_26 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0006651 43.0
HKD1_k127_7047334_3 SMART Signal transduction response regulator, receiver region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 586.0
HKD1_k127_7047334_4 amino acid transport system, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 567.0
HKD1_k127_7047334_5 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 542.0
HKD1_k127_7047334_6 nitrogen fixation negative regulator NifL - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 546.0
HKD1_k127_7047334_7 ATP-binding region, ATPase domain protein K02482,K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 520.0
HKD1_k127_7047334_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 438.0
HKD1_k127_7047334_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 414.0
HKD1_k127_7062073_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1110.0
HKD1_k127_7062073_1 Circularly permuted ATP-grasp type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 409.0
HKD1_k127_7066173_0 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 6.232e-209 662.0
HKD1_k127_7066173_1 acetylornithine aminotransferase K00821,K00840 GO:0003674,GO:0003824,GO:0003992,GO:0004069,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006553,GO:0006591,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009016,GO:0009058,GO:0009064,GO:0009066,GO:0009067,GO:0009084,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0036094,GO:0042450,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17,2.6.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 550.0
HKD1_k127_7066173_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 410.0
HKD1_k127_7066173_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000003315 265.0
HKD1_k127_7066173_4 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000154 230.0
HKD1_k127_7066173_5 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000008819 138.0
HKD1_k127_7066173_6 Protein of unknown function (DUF465) - - - 0.00000000000000002653 83.0
HKD1_k127_7086414_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1387.0
HKD1_k127_7086414_1 Protein export membrane protein K07239 - - 0.0 1262.0
HKD1_k127_7086414_10 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 334.0
HKD1_k127_7086414_11 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 299.0
HKD1_k127_7086414_12 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001673 258.0
HKD1_k127_7086414_13 membrane-bound metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005026 239.0
HKD1_k127_7086414_14 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000006141 231.0
HKD1_k127_7086414_15 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000000002816 180.0
HKD1_k127_7086414_16 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.00000000000000000000000000000000000000000000004693 173.0
HKD1_k127_7086414_17 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000222 154.0
HKD1_k127_7086414_18 Sigma 54 modulation protein K05808 - - 0.000000000000000000000000000000000000005589 149.0
HKD1_k127_7086414_19 Phosphotransferase System K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.00000000000000000000000000002205 119.0
HKD1_k127_7086414_2 C-terminal, D2-small domain, of ClpB protein K03694 - - 0.0 1076.0
HKD1_k127_7086414_20 Protein of unknown function (DUF2970) - - - 0.000000000000000001726 86.0
HKD1_k127_7086414_21 High confidence in function and specificity - - - 0.0000000002122 66.0
HKD1_k127_7086414_3 FtsX-like permease family K02004 - - 1.591e-251 801.0
HKD1_k127_7086414_4 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.487e-215 683.0
HKD1_k127_7086414_5 ABC transporter - - - 2.031e-214 669.0
HKD1_k127_7086414_6 1,4-alpha-glucan branching enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 593.0
HKD1_k127_7086414_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 557.0
HKD1_k127_7086414_8 PFAM Uncharacterised conserved protein UCP029693 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 481.0
HKD1_k127_7086414_9 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 333.0
HKD1_k127_7089306_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.00000000000000000000000000000000000000000000000642 179.0
HKD1_k127_7089306_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000008192 175.0
HKD1_k127_7089306_2 transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000003221 128.0
HKD1_k127_7089306_3 SNAP receptor activity - - - 0.000000000000000000000000000007258 125.0
HKD1_k127_7089306_4 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000002257 122.0
HKD1_k127_7089306_5 mRNA binding - - - 0.000000000000000000000000004959 111.0
HKD1_k127_7089306_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000718 76.0
HKD1_k127_7089306_7 Transposase - - - 0.0000000000004018 73.0
HKD1_k127_7089306_8 Transposase (IS116 IS110 IS902 family) - - - 0.00000005061 55.0
HKD1_k127_7091868_0 double-stranded DNA endodeoxyribonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009928 264.0
HKD1_k127_7091868_1 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000137 112.0
HKD1_k127_7122212_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 543.0
HKD1_k127_7122212_1 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 346.0
HKD1_k127_7122212_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000002113 176.0
HKD1_k127_7179789_0 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 493.0
HKD1_k127_7179789_1 glutamate--cysteine ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 356.0
HKD1_k127_7179789_2 transcriptional - - - 0.0000000000000000000000000000000000007483 144.0
HKD1_k127_7180734_0 Cysteine-rich domain K00113,K11473 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 611.0
HKD1_k127_7180734_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 462.0
HKD1_k127_7180734_2 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001147 252.0
HKD1_k127_7180734_3 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002088 240.0
HKD1_k127_7180734_4 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0000000000000000000000000000000001763 133.0
HKD1_k127_7192937_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1521.0
HKD1_k127_7192937_1 small GTP-binding protein K02355 - - 0.00000000000000000000000000000000000000000000000000000000000433 211.0
HKD1_k127_7227291_0 SNF2 family N-terminal domain - - - 0.0 1226.0
HKD1_k127_7227291_1 Swim zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 340.0
HKD1_k127_7227291_2 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 327.0
HKD1_k127_7227291_3 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 310.0
HKD1_k127_7227291_4 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000897 165.0
HKD1_k127_722957_0 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 582.0
HKD1_k127_722957_1 Bacterial type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 522.0
HKD1_k127_722957_2 TIGRFAM general secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000002983 232.0
HKD1_k127_722957_3 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.0000000000000000000005337 96.0
HKD1_k127_7276066_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 3.642e-270 839.0
HKD1_k127_7276066_1 PFAM cobalamin synthesis protein P47K - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 399.0
HKD1_k127_7276066_2 Putative Fe-S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 360.0
HKD1_k127_7276066_3 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000822 278.0
HKD1_k127_7276066_4 Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.000000000000000000000000000000000000000000001099 169.0
HKD1_k127_7276066_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000002217 139.0
HKD1_k127_7276066_6 2 iron, 2 sulfur cluster binding K13643 - - 0.00000000000000000000000000001539 118.0
HKD1_k127_7276066_7 PFAM ABC transporter related - - - 0.000000001801 63.0
HKD1_k127_7278382_0 COG2801 Transposase and inactivated derivatives - - - 9.285e-243 761.0
HKD1_k127_7278382_1 Type II secretory pathway component ExeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 309.0
HKD1_k127_7278382_2 DNA invertase Pin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002089 274.0
HKD1_k127_7278382_3 Phage plasmid primase, P4 K06919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000646 273.0
HKD1_k127_7278553_0 Aminotransferase class-III K00836 - 2.6.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 479.0
HKD1_k127_7278553_1 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 426.0
HKD1_k127_7278553_10 DDE domain - - - 0.000000000000000001257 90.0
HKD1_k127_7278553_11 - K07498 - - 0.0000000000000001869 81.0
HKD1_k127_7278553_12 - K07498 - - 0.0000000003234 61.0
HKD1_k127_7278553_13 - - - - 0.000006165 53.0
HKD1_k127_7278553_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 302.0
HKD1_k127_7278553_3 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000001072 254.0
HKD1_k127_7278553_4 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003226 242.0
HKD1_k127_7278553_5 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000002646 244.0
HKD1_k127_7278553_6 Glycosyl hydrolases family 31 K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000009387 214.0
HKD1_k127_7278553_7 MbtH-like protein K05375,K09190 - - 0.000000000000000000000000000002254 124.0
HKD1_k127_7278553_8 Alpha amylase, catalytic domain K00700,K01236 - 2.4.1.18,3.2.1.141 0.00000000000000000000000000005559 129.0
HKD1_k127_7278553_9 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000000003268 121.0
HKD1_k127_7284200_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.037e-288 906.0
HKD1_k127_7284200_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 385.0
HKD1_k127_7284200_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 347.0
HKD1_k127_7284200_3 Cobalt uptake substrate-specific transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 325.0
HKD1_k127_7284200_4 Cobalt transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000006813 227.0
HKD1_k127_7284200_5 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008819,GO:0008820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0033554,GO:0044237,GO:0050896,GO:0051716,GO:0070568 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000000000000000003534 220.0
HKD1_k127_7284200_6 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.0000000000000000000000000005893 121.0
HKD1_k127_7284200_7 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02009 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000006407 107.0
HKD1_k127_7284200_8 PFAM Resolvase - - - 0.00002593 48.0
HKD1_k127_7293340_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1245.0
HKD1_k127_7293340_1 Formyl transferase, C-terminal domain K10011,K12449 - 1.1.1.305,2.1.2.13 5.695e-292 909.0
HKD1_k127_7293340_10 Phosphate acetyl/butaryl transferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 516.0
HKD1_k127_7293340_11 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 481.0
HKD1_k127_7293340_12 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 436.0
HKD1_k127_7293340_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 430.0
HKD1_k127_7293340_14 Glycosyltransferase like family 2 K10012,K20534 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 410.0
HKD1_k127_7293340_15 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 412.0
HKD1_k127_7293340_16 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 373.0
HKD1_k127_7293340_17 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 372.0
HKD1_k127_7293340_18 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 325.0
HKD1_k127_7293340_19 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 303.0
HKD1_k127_7293340_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 7.29e-286 889.0
HKD1_k127_7293340_20 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000001629 252.0
HKD1_k127_7293340_21 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000001039 245.0
HKD1_k127_7293340_22 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000001472 241.0
HKD1_k127_7293340_23 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.000000000000000000000000000000000000000000000000000000000001516 240.0
HKD1_k127_7293340_24 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000005654 164.0
HKD1_k127_7293340_25 DNA-binding protein, H-NS K03746 - - 0.000000000000000002551 89.0
HKD1_k127_7293340_26 Anaphase-promoting complex subunit 4 WD40 domain - - - 0.0000000000004617 76.0
HKD1_k127_7293340_27 hydrolase, TatD family K03424 - - 0.000000000003851 67.0
HKD1_k127_7293340_28 lipolytic protein G-D-S-L family K01179,K01183 - 3.2.1.14,3.2.1.4 0.00002354 48.0
HKD1_k127_7293340_29 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00005941 48.0
HKD1_k127_7293340_3 alpha beta hydrolase fold K03821 - - 1.27e-243 766.0
HKD1_k127_7293340_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 3.862e-220 691.0
HKD1_k127_7293340_5 Diguanylate cyclase - - - 3.392e-205 655.0
HKD1_k127_7293340_6 Threonine synthase K01733 - 4.2.3.1 5.181e-205 648.0
HKD1_k127_7293340_7 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 1.056e-197 627.0
HKD1_k127_7293340_8 Belongs to the mannose-6-phosphate isomerase type 2 family K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 612.0
HKD1_k127_7293340_9 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 534.0
HKD1_k127_7298792_0 Sulfate permease family K03321 - - 1.331e-199 637.0
HKD1_k127_7298792_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 484.0
HKD1_k127_7298792_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 379.0
HKD1_k127_7298792_3 Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non- specifically the aggregation of denaturated periplasmic proteins K19777 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0042802,GO:0050896,GO:0051087,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0104004 - 0.000000000000005657 81.0
HKD1_k127_7298792_4 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0010876,GO:0016020,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0034613,GO:0042157,GO:0042277,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0051668,GO:0070727,GO:0071704,GO:0071723,GO:0071944,GO:0072657,GO:1901564 - 0.000000002913 62.0
HKD1_k127_7298792_5 - - - - 0.00000006044 61.0
HKD1_k127_7319663_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 550.0
HKD1_k127_7319663_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 537.0
HKD1_k127_7319663_10 - - - - 0.0000004084 53.0
HKD1_k127_7319663_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 304.0
HKD1_k127_7319663_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 312.0
HKD1_k127_7319663_4 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000000002366 181.0
HKD1_k127_7319663_5 Invasion gene expression up-regulator SirB - - - 0.000000000000000000000000000000000000001444 150.0
HKD1_k127_7319663_6 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000001244 142.0
HKD1_k127_7319663_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000001101 140.0
HKD1_k127_7319663_8 PFAM transposase, IS4 family protein - - - 0.00000000000002745 76.0
HKD1_k127_7336868_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 505.0
HKD1_k127_7336868_1 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000961 464.0
HKD1_k127_7336868_2 Pfam ABC transporter related K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 333.0
HKD1_k127_7336868_3 in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 318.0
HKD1_k127_7336868_4 glycosyl - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008218 254.0
HKD1_k127_7336868_5 PFAM Cobalt transport protein K02007,K02008 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000008989 254.0
HKD1_k127_7336868_6 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006652 241.0
HKD1_k127_7336868_7 - - - - 0.0000228 50.0
HKD1_k127_7350116_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 369.0
HKD1_k127_7350116_1 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 344.0
HKD1_k127_7350116_2 Cache domain - - - 0.000000000000000000000000000000000000000000000001437 189.0
HKD1_k127_7350116_3 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000002941 179.0
HKD1_k127_7350116_4 SpoIIAA-like - - - 0.000000000000000002977 89.0
HKD1_k127_7391355_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 1.115e-314 970.0
HKD1_k127_7391355_1 Superfamily II DNA RNA helicase, SNF2 family - - - 1.215e-305 949.0
HKD1_k127_7391355_10 Belongs to the urease beta subunit family K01429 GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009039,GO:0016787,GO:0016810,GO:0016811 3.5.1.5 0.0000000000000000000000000000000000000000000005489 168.0
HKD1_k127_7391355_11 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000001525 171.0
HKD1_k127_7391355_12 Periplasmic binding protein domain K11959 - - 0.0000000000000000000000000000000000000000002413 160.0
HKD1_k127_7391355_13 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000002184 100.0
HKD1_k127_7391355_14 - - - - 0.000000000000000000000496 98.0
HKD1_k127_7391355_2 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 544.0
HKD1_k127_7391355_3 Papain cysteine protease family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 394.0
HKD1_k127_7391355_4 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 346.0
HKD1_k127_7391355_5 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 329.0
HKD1_k127_7391355_6 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 296.0
HKD1_k127_7391355_7 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002623 282.0
HKD1_k127_7391355_8 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007271 273.0
HKD1_k127_7391355_9 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.00000000000000000000000000000000000000000000001102 172.0
HKD1_k127_7409656_0 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 469.0
HKD1_k127_7409656_1 sulfate ABC transporter K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 400.0
HKD1_k127_7409656_2 zinc protease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 370.0
HKD1_k127_7409656_3 NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 347.0
HKD1_k127_7409656_4 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 281.0
HKD1_k127_7411021_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 457.0
HKD1_k127_7411021_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 435.0
HKD1_k127_7411021_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 332.0
HKD1_k127_7411021_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000395 283.0
HKD1_k127_7411021_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000005214 132.0
HKD1_k127_7411021_5 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000375 93.0
HKD1_k127_7411021_6 ACR protein K07040 - - 0.00000000000000000005874 96.0
HKD1_k127_7418302_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1388.0
HKD1_k127_7418302_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 2.64e-231 722.0
HKD1_k127_7418302_10 Protein conserved in bacteria K03427,K04066 - 2.1.1.72 0.000000000000000000000000000000008954 132.0
HKD1_k127_7418302_11 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000004604 115.0
HKD1_k127_7418302_12 positive regulation of growth - - - 0.0000000000000000001343 90.0
HKD1_k127_7418302_13 - - - - 0.0000000000001418 72.0
HKD1_k127_7418302_14 PIN domain K07064 - - 0.0000000000001445 71.0
HKD1_k127_7418302_15 PIN domain K07064 - - 0.000000000004861 68.0
HKD1_k127_7418302_16 - - - - 0.00000000005372 66.0
HKD1_k127_7418302_17 - - - - 0.000000003335 57.0
HKD1_k127_7418302_18 - - - - 0.0000009881 50.0
HKD1_k127_7418302_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 9.49e-220 693.0
HKD1_k127_7418302_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 550.0
HKD1_k127_7418302_4 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002037 265.0
HKD1_k127_7418302_5 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000004531 248.0
HKD1_k127_7418302_6 Pyruvate ferredoxin oxidoreductase K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000001479 244.0
HKD1_k127_7418302_7 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003332 251.0
HKD1_k127_7418302_8 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000007106 208.0
HKD1_k127_7418302_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000001903 186.0
HKD1_k127_74316_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 1.868e-264 824.0
HKD1_k127_74316_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 350.0
HKD1_k127_74316_2 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 290.0
HKD1_k127_74316_3 - - - - 0.000000000000888 70.0
HKD1_k127_7434580_0 membrane K14205 - 2.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 595.0
HKD1_k127_7434580_1 sulfuric ester hydrolase activity K07014 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 592.0
HKD1_k127_7434580_2 Protein of unknown function, DUF484 K09921 - - 0.0000000000000003441 82.0
HKD1_k127_7447719_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.547e-300 930.0
HKD1_k127_7447719_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.178e-250 784.0
HKD1_k127_7447719_10 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000002475 134.0
HKD1_k127_7447719_11 Anti sigma-E protein RseA, N-terminal domain K03597 - - 0.000000000000000001161 93.0
HKD1_k127_7447719_12 Domain of unknown function (DUF4845) - - - 0.0000000000000001366 85.0
HKD1_k127_7447719_13 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.00000000000001348 77.0
HKD1_k127_7447719_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 359.0
HKD1_k127_7447719_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 333.0
HKD1_k127_7447719_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 298.0
HKD1_k127_7447719_5 Belongs to the peptidase S26 family K03100 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 293.0
HKD1_k127_7447719_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000002142 233.0
HKD1_k127_7447719_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000003202 201.0
HKD1_k127_7447719_8 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.00000000000000000000000000000000000000000000000002327 183.0
HKD1_k127_7447719_9 PFAM MucB RseB K03598 - - 0.0000000000000000000000000000000000000000000000007918 188.0
HKD1_k127_74592_0 Histidine kinase K11527 - 2.7.13.3 4.09e-254 845.0
HKD1_k127_74592_1 Asparagine synthase K01953 - 6.3.5.4 1.67e-196 630.0
HKD1_k127_74592_10 - - - - 0.000000000000000000001908 108.0
HKD1_k127_74592_2 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 550.0
HKD1_k127_74592_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 489.0
HKD1_k127_74592_4 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000007476 190.0
HKD1_k127_74592_6 Protein of unknown function (DUF499) K06922 - - 0.0000000000000000000000000000000000000000006161 160.0
HKD1_k127_74592_7 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000004668 149.0
HKD1_k127_74592_8 Acyltransferase family - - - 0.000000000000000000000000000000000003816 152.0
HKD1_k127_74592_9 ABC transporter K06147 - - 0.0000000000000000000000000907 112.0
HKD1_k127_7460502_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 526.0
HKD1_k127_7460502_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000005588 234.0
HKD1_k127_7460502_2 Methyltransferase K15256 - - 0.0000000000000000000000000000000000000000000000000000000002803 213.0
HKD1_k127_7460502_3 Transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000001473 174.0
HKD1_k127_7460502_4 - - - - 0.0000000002999 63.0
HKD1_k127_7460502_5 Transposase K07491 - - 0.0000000009167 59.0
HKD1_k127_7460502_6 - - - - 0.00004342 49.0
HKD1_k127_7468395_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 2.534e-281 874.0
HKD1_k127_7468395_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 1.104e-269 839.0
HKD1_k127_7468395_2 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000001192 224.0
HKD1_k127_7468395_3 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000133 166.0
HKD1_k127_7479688_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.754e-247 767.0
HKD1_k127_7479688_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 2.438e-208 654.0
HKD1_k127_7479688_10 Phosphoesterase family K21302 - 3.1.3.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000005025 275.0
HKD1_k127_7479688_11 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 262.0
HKD1_k127_7479688_12 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000000000000003948 261.0
HKD1_k127_7479688_13 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000008365 228.0
HKD1_k127_7479688_14 Protein of unknown function (DUF1249) K09920 - - 0.0000000000000000000000000000000000001314 147.0
HKD1_k127_7479688_15 Rubredoxin - - - 0.000000000000000000000000002081 111.0
HKD1_k127_7479688_16 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000002159 109.0
HKD1_k127_7479688_17 - - - - 0.0000000000000000004999 92.0
HKD1_k127_7479688_18 pfam abc K09695 - - 0.0000000000000000009032 90.0
HKD1_k127_7479688_19 surface antigen variable number repeat protein K07001 - - 0.0000006807 54.0
HKD1_k127_7479688_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 2.1e-207 649.0
HKD1_k127_7479688_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 512.0
HKD1_k127_7479688_4 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 487.0
HKD1_k127_7479688_5 transport system, permease component K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 450.0
HKD1_k127_7479688_6 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 412.0
HKD1_k127_7479688_7 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 382.0
HKD1_k127_7479688_8 PFAM O-methyltransferase family 3 K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 310.0
HKD1_k127_7479688_9 PFAM Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000004992 265.0
HKD1_k127_7487489_0 PFAM Mannosyl oligosaccharide glucosidase - - - 0.0 1322.0
HKD1_k127_7487489_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.505e-212 669.0
HKD1_k127_7487489_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006315 250.0
HKD1_k127_7487489_11 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009888 248.0
HKD1_k127_7487489_12 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000001036 245.0
HKD1_k127_7487489_13 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000007177 188.0
HKD1_k127_7487489_14 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000003081 184.0
HKD1_k127_7487489_15 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000004763 187.0
HKD1_k127_7487489_16 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000008197 177.0
HKD1_k127_7487489_17 cytochrome - - - 0.000000000000000000000000000000000000000000004654 169.0
HKD1_k127_7487489_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000111 170.0
HKD1_k127_7487489_19 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000001662 159.0
HKD1_k127_7487489_2 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 530.0
HKD1_k127_7487489_20 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000001571 132.0
HKD1_k127_7487489_21 lipoprotein biosynthetic process - - - 0.000000000000000000000000000001051 136.0
HKD1_k127_7487489_22 Putative zinc-finger - - - 0.000000000000000000000001215 113.0
HKD1_k127_7487489_23 Domain of unknown function (DUF4157) - - - 0.000000000000000000279 102.0
HKD1_k127_7487489_24 SPTR Transposase, IS4 family protein - - - 0.000000000000057 74.0
HKD1_k127_7487489_25 Peptidase S24-like - - - 0.0000003407 57.0
HKD1_k127_7487489_26 protein conserved in cyanobacteria - - - 0.00007494 46.0
HKD1_k127_7487489_3 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 480.0
HKD1_k127_7487489_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 480.0
HKD1_k127_7487489_5 PEP-CTERM motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 407.0
HKD1_k127_7487489_6 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 388.0
HKD1_k127_7487489_7 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009688 341.0
HKD1_k127_7487489_8 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 349.0
HKD1_k127_7487489_9 glutathione s-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001789 281.0
HKD1_k127_7494210_0 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 484.0
HKD1_k127_7494210_1 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 394.0
HKD1_k127_7494210_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000002098 209.0
HKD1_k127_7494210_3 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000000000000000003137 168.0
HKD1_k127_7494210_4 PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30 - - - 0.00000000000000000000000000000000000004769 153.0
HKD1_k127_7589763_0 metabolite transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 510.0
HKD1_k127_7589763_1 Chromate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 475.0
HKD1_k127_7589763_2 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 428.0
HKD1_k127_7589763_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 301.0
HKD1_k127_7589763_4 GDSL-like Lipase/Acylhydrolase K12686 - - 0.0000000000000000000000000000000000000000000000000000468 203.0
HKD1_k127_7589763_5 DDE superfamily endonuclease - - - 0.000000000002971 72.0
HKD1_k127_7589763_6 - - - - 0.00000000004919 64.0
HKD1_k127_7589763_7 SPTR B0JN73 Transposase - - - 0.00000004143 59.0
HKD1_k127_7589763_8 Winged helix-turn helix - - - 0.00000009992 56.0
HKD1_k127_7591743_0 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 442.0
HKD1_k127_7591743_1 KR domain K00034 - 1.1.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 403.0
HKD1_k127_7591743_2 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 341.0
HKD1_k127_7591743_3 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003187 250.0
HKD1_k127_7591743_4 - - - - 0.0000000000000000003818 89.0
HKD1_k127_7596185_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1222.0
HKD1_k127_7596185_1 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 3.611e-298 934.0
HKD1_k127_7596185_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 521.0
HKD1_k127_7596185_11 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 388.0
HKD1_k127_7596185_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 329.0
HKD1_k127_7596185_13 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001496 285.0
HKD1_k127_7596185_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004443 277.0
HKD1_k127_7596185_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002452 274.0
HKD1_k127_7596185_16 Pfam:PNPOx_C K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001891 268.0
HKD1_k127_7596185_17 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001006 257.0
HKD1_k127_7596185_18 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000006466 242.0
HKD1_k127_7596185_19 lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000001074 220.0
HKD1_k127_7596185_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.877e-287 895.0
HKD1_k127_7596185_20 Putative diguanylate phosphodiesterase K21025 - - 0.000000000000000000000000000000000000000000000000000000179 220.0
HKD1_k127_7596185_21 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000009166 184.0
HKD1_k127_7596185_22 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000000000005861 168.0
HKD1_k127_7596185_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000009977 158.0
HKD1_k127_7596185_24 pilin assembly protein - - - 0.0000000000000000000000000000000000001497 143.0
HKD1_k127_7596185_25 Phasin protein - - - 0.0000000000000000000000000000000221 131.0
HKD1_k127_7596185_26 Belongs to the 'phage' integrase family - - - 0.00000000000000000000001525 99.0
HKD1_k127_7596185_27 - - - - 0.000000000000000000003367 99.0
HKD1_k127_7596185_28 Putative prokaryotic signal transducing protein - - - 0.00000000000002488 74.0
HKD1_k127_7596185_29 transposase activity - - - 0.000000213 53.0
HKD1_k127_7596185_3 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 8.609e-257 804.0
HKD1_k127_7596185_30 (Lipo)protein - - - 0.000001378 53.0
HKD1_k127_7596185_31 Histidine kinase - - - 0.000001856 61.0
HKD1_k127_7596185_32 - - - - 0.000002543 54.0
HKD1_k127_7596185_33 Histidine kinase - - - 0.0003527 54.0
HKD1_k127_7596185_4 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 1.403e-252 795.0
HKD1_k127_7596185_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.175e-242 753.0
HKD1_k127_7596185_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 3.943e-236 735.0
HKD1_k127_7596185_7 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 1.448e-231 730.0
HKD1_k127_7596185_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 591.0
HKD1_k127_7596185_9 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 561.0
HKD1_k127_7599116_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.915e-321 992.0
HKD1_k127_7599116_1 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 531.0
HKD1_k127_7599116_11 sequence-specific DNA binding K03557,K07712 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00005403 47.0
HKD1_k127_7599116_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 346.0
HKD1_k127_7599116_3 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 308.0
HKD1_k127_7599116_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000003341 269.0
HKD1_k127_7599116_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000004142 218.0
HKD1_k127_7599116_6 CRS1_YhbY K07574 - - 0.0000000000000000000000000001887 117.0
HKD1_k127_7599116_7 - - - - 0.00000000000000000000004328 100.0
HKD1_k127_7599116_8 Domain of unknown function (DUF4149) - - - 0.00000000000000000009648 94.0
HKD1_k127_7688325_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.0 1069.0
HKD1_k127_7688325_1 nuclear chromosome segregation K07053,K18491 - 3.1.3.97 3.071e-315 988.0
HKD1_k127_7688325_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000002339 195.0
HKD1_k127_7688325_11 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000000000000000000000002968 178.0
HKD1_k127_7688325_12 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000001245 127.0
HKD1_k127_7688325_13 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.00000000000000001622 87.0
HKD1_k127_7688325_14 Protein of unknown function (DUF4231) - - - 0.00000000000000006628 90.0
HKD1_k127_7688325_15 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000007747 81.0
HKD1_k127_7688325_2 WD40 repeats K20332 - - 6.135e-307 955.0
HKD1_k127_7688325_3 Domain of unknown function (DUF4071) - - - 1.315e-285 890.0
HKD1_k127_7688325_4 PFAM Peptidase family M20 M25 M40 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 500.0
HKD1_k127_7688325_5 Putative DNA-binding domain K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 427.0
HKD1_k127_7688325_6 Belongs to the RNA methyltransferase TrmD family K00554 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 342.0
HKD1_k127_7688325_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004937 274.0
HKD1_k127_7688325_8 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000000000001503 230.0
HKD1_k127_7688325_9 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000003404 199.0
HKD1_k127_7703998_0 SMART Nucleotide binding protein, PINc K07175 - - 1.418e-223 700.0
HKD1_k127_7703998_1 HpcH/HpaI aldolase/citrate lyase family - - - 7.146e-199 638.0
HKD1_k127_7703998_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 422.0
HKD1_k127_7703998_3 AI-2E family transporter K03548 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 401.0
HKD1_k127_7703998_4 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 346.0
HKD1_k127_7703998_5 (Lipo)protein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 302.0
HKD1_k127_7703998_6 ACT domain K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000002978 233.0
HKD1_k127_7703998_7 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000004131 212.0
HKD1_k127_7703998_8 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000002211 194.0
HKD1_k127_7703998_9 PEP-CTERM system TPR-repeat lipoprotein - - - 0.000000000000000000000000000000000000000000001611 175.0
HKD1_k127_7788280_0 cystathionine K01739,K01758 - 2.5.1.48,4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 604.0
HKD1_k127_7788280_1 Transcriptional regulator - - - 0.000000000000000000000000000000002255 132.0
HKD1_k127_7801720_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 6.698e-230 730.0
HKD1_k127_7801720_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 4.853e-215 677.0
HKD1_k127_7801720_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000000000000000000000000001235 121.0
HKD1_k127_7824201_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.252e-204 642.0
HKD1_k127_7824201_1 Glycosyl hydrolases family 15 K07190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 527.0
HKD1_k127_784636_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1283.0
HKD1_k127_784636_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 5.188e-213 669.0
HKD1_k127_784636_2 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 600.0
HKD1_k127_784636_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 459.0
HKD1_k127_784636_4 JAB/MPN domain K21140 - 3.13.1.6 0.00000000000000000000000000000000000000236 150.0
HKD1_k127_784636_5 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000004937 135.0
HKD1_k127_784636_6 TIGRFAM MoaD family protein K03636 - - 0.000000000000000000000004499 104.0
HKD1_k127_784636_7 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000004441 83.0
HKD1_k127_784636_8 Phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.000001612 50.0
HKD1_k127_7869711_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0 1411.0
HKD1_k127_7869711_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 408.0
HKD1_k127_7869711_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 390.0
HKD1_k127_7869711_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885,K15977 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 343.0
HKD1_k127_7873772_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 2348.0
HKD1_k127_7873772_1 modulator of DNA gyrase K03568 - - 6.747e-231 722.0
HKD1_k127_7873772_2 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 567.0
HKD1_k127_7873772_3 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 522.0
HKD1_k127_7873772_4 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 377.0
HKD1_k127_7873772_5 Belongs to the UPF0307 family K09889 - - 0.00000000000000000001208 96.0
HKD1_k127_7888524_0 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 477.0
HKD1_k127_7888524_1 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003657 269.0
HKD1_k127_7888524_2 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000002196 156.0
HKD1_k127_7906136_0 PFAM Sulphatase-modifying factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 485.0
HKD1_k127_7906136_1 PINc domain ribonuclease K09006 - - 0.0000000000000000000000000000000000000000000000000000000000000000006908 233.0
HKD1_k127_7906136_2 RNA ligase K07468 - 6.5.1.1 0.0000000000000000000000000000000000000001718 154.0
HKD1_k127_7906136_3 PFAM ATP dependent DNA ligase K07468 - 6.5.1.1 0.000000000000000000000000000393 115.0
HKD1_k127_7930817_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 486.0
HKD1_k127_7930817_1 PAS domain containing protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 458.0
HKD1_k127_7930817_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002671 261.0
HKD1_k127_7930817_3 Zinc-binding domain of primase-helicase K06919 - - 0.0000000000000000000000000000000000000000000003683 174.0
HKD1_k127_7930817_4 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000006648 109.0
HKD1_k127_7930817_5 - - - - 0.00000000000000000000004111 101.0
HKD1_k127_7941102_0 aldehyde ferredoxin oxidoreductase activity K03738,K11389 - 1.2.7.5,1.2.7.6 1.281e-240 760.0
HKD1_k127_7941102_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 336.0
HKD1_k127_7941102_2 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000008498 172.0
HKD1_k127_7941102_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000006907 126.0
HKD1_k127_7955187_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 383.0
HKD1_k127_7955187_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002617 284.0
HKD1_k127_7955187_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008270,GO:0008685,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016849,GO:0030145,GO:0042180,GO:0042181,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000005576 231.0
HKD1_k127_7955187_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000009988 95.0
HKD1_k127_7976090_0 small GTP-binding protein K02355 - - 1.298e-228 718.0
HKD1_k127_7976090_1 TolA C-terminal K03646 - - 0.00000000000000001043 89.0
HKD1_k127_7976090_2 Rhodopirellula transposase DDE domain - - - 0.0009538 45.0
HKD1_k127_8003466_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 5.007e-271 853.0
HKD1_k127_8003466_1 Involved in initiation control of chromosome replication - - - 0.00000000000000000000000000000000000000000000000006061 184.0
HKD1_k127_8003466_2 Domain of unknown function DUF29 - - - 0.00000000000000000000000000000000006673 139.0
HKD1_k127_8003466_3 Domain of unknown function (DUF4160) - - - 0.000000000000000000000000000001222 125.0
HKD1_k127_8003466_4 EamA-like transporter family - - - 0.000000000000000000001048 104.0
HKD1_k127_8003466_5 Protein of unknown function (DUF2442) - - - 0.000000000000000002937 87.0
HKD1_k127_8003466_6 COG3436 Transposase and inactivated derivatives - - - 0.000000000000004534 79.0
HKD1_k127_8003466_7 PFAM Uncharacterised protein family UPF0175 - - - 0.00000001112 60.0
HKD1_k127_8014188_0 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 382.0
HKD1_k127_8014188_1 PFAM Archaeal ATPase - - - 0.000000000000000000000000000000000000000000000002069 175.0
HKD1_k127_8014188_2 PFAM NifQ K15790 - - 0.000000000000000000000000000000000000000001914 157.0
HKD1_k127_8014188_3 protein conserved in cyanobacteria - - - 0.0000000001328 64.0
HKD1_k127_8014188_4 PFAM Archaeal ATPase - - - 0.0000007452 50.0
HKD1_k127_8036201_0 Bacterial regulatory protein, Fis family K02481,K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 514.0
HKD1_k127_8036201_1 ion channel K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 521.0
HKD1_k127_8036201_10 PFAM DoxX K15977 - - 0.000000000000000000000000000000000000575 143.0
HKD1_k127_8036201_11 Tetratricopeptide repeat - - - 0.00000000000000002883 94.0
HKD1_k127_8036201_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 378.0
HKD1_k127_8036201_3 Histidine kinase K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 365.0
HKD1_k127_8036201_4 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 324.0
HKD1_k127_8036201_5 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 322.0
HKD1_k127_8036201_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005317 263.0
HKD1_k127_8036201_7 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000004869 213.0
HKD1_k127_8036201_8 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000006469 194.0
HKD1_k127_8036201_9 Phage shock protein A K03969 - - 0.0000000000000000000000000000000000000000000001891 175.0
HKD1_k127_84687_0 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 531.0
HKD1_k127_84687_1 lipid kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007222 280.0
HKD1_k127_84687_2 recombinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000247 235.0
HKD1_k127_84687_3 PAP2 superfamily - - - 0.00000003048 61.0
HKD1_k127_84687_4 membrane - - - 0.0000002532 59.0
HKD1_k127_84687_5 RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities K03607 - - 0.000005486 55.0
HKD1_k127_854861_0 PFAM transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000161 196.0
HKD1_k127_854861_1 kinase activity K01006,K01007,K22424 - 2.7.3.13,2.7.9.1,2.7.9.2 0.000000000005084 68.0
HKD1_k127_858810_0 Protein of unknown function (DUF3604) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 583.0
HKD1_k127_858810_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 344.0
HKD1_k127_858810_2 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000005873 187.0
HKD1_k127_858810_3 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000000000007592 125.0
HKD1_k127_858810_4 Transcriptional regulator - - - 0.0000000000000000000000001792 109.0
HKD1_k127_888323_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.465e-280 872.0
HKD1_k127_888323_1 S-acyltransferase activity K00627 - 2.3.1.12 0.000000000000000000000000000000000000009825 149.0
HKD1_k127_888323_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000000000000000000001808 98.0
HKD1_k127_888323_3 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.0000000000000003988 81.0
HKD1_k127_888323_4 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 0.0000000000001196 72.0
HKD1_k127_904992_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 6.468e-301 938.0
HKD1_k127_904992_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 577.0
HKD1_k127_904992_2 Efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 536.0
HKD1_k127_904992_3 Superfamily II DNA RNA helicase, SNF2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 315.0
HKD1_k127_922291_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 329.0
HKD1_k127_922291_1 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 312.0
HKD1_k127_931452_0 Phage tail sheath protein subtilisin-like domain K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 573.0
HKD1_k127_931452_1 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 522.0
HKD1_k127_931452_10 - - - - 0.000000000000000000000000000000000000000000000000000001595 205.0
HKD1_k127_931452_11 - - - - 0.00000000000000000000000000000000000000000000000000001276 194.0
HKD1_k127_931452_13 radical SAM K06871 - - 0.00000000009947 63.0
HKD1_k127_931452_2 InterPro IPR008538 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 386.0
HKD1_k127_931452_3 Sigma-54 interaction domain K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 385.0
HKD1_k127_931452_4 PFAM ErfK YbiS YcfS YnhG family protein K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 349.0
HKD1_k127_931452_5 Histidine kinase K02482,K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 316.0
HKD1_k127_931452_6 Biotin-lipoyl like K01993 - - 0.000000000000000000000000000000000000000000000000000000000000002851 229.0
HKD1_k127_931452_7 - - - - 0.000000000000000000000000000000000000000000000000000000000001468 213.0
HKD1_k127_931452_8 response regulator receiver K13041 - - 0.0000000000000000000000000000000000000000000000000000005122 201.0
HKD1_k127_931452_9 ABC transporter, ATP-binding protein K01990 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0022857,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000006098 202.0
HKD1_k127_962442_0 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 1.682e-278 863.0
HKD1_k127_962442_1 Nitrogenase molybdenum-iron protein alpha chain K02586 - 1.18.6.1 6.473e-264 820.0
HKD1_k127_962442_10 Protein of unknown function (DUF3604) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 309.0
HKD1_k127_962442_11 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000000000000000000000000000000000004753 233.0
HKD1_k127_962442_12 Low-potential electron donor to a number of redox enzymes K03839,K03840 - - 0.000000000000000000000000000000000000000000000000000000000004927 212.0
HKD1_k127_962442_13 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000005726 158.0
HKD1_k127_962442_14 PFAM NifT FixU K02593 - - 0.00000000000000000000003065 100.0
HKD1_k127_962442_2 Belongs to the NifD NifK NifE NifN family K02587 - - 3.233e-243 757.0
HKD1_k127_962442_3 Arylsulfatase K01130 - 3.1.6.1 7.015e-199 640.0
HKD1_k127_962442_4 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 501.0
HKD1_k127_962442_5 Nitrogenase component 1 type Oxidoreductase K02592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 434.0
HKD1_k127_962442_6 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 383.0
HKD1_k127_962442_7 PFAM Dinitrogenase reductase ADP-ribosyltransferase K05951 - 2.4.2.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 348.0
HKD1_k127_962442_8 Protein of unknown function (DUF3604) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 363.0
HKD1_k127_962442_9 Protein of unknown function (DUF3604) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 328.0
HKD1_k127_971330_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1567.0
HKD1_k127_971330_1 PFAM Glycoside hydrolase 15-related - - - 0.0 1042.0
HKD1_k127_971330_10 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000257 271.0
HKD1_k127_971330_11 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000005056 268.0
HKD1_k127_971330_12 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.000000000000000000000000000000000000000000000002388 177.0
HKD1_k127_971330_13 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000593 173.0
HKD1_k127_971330_14 cAMP biosynthetic process - - - 0.00000000000000000000000000000000007756 141.0
HKD1_k127_971330_15 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.00000000000000000006856 91.0
HKD1_k127_971330_16 - - - - 0.00000000004771 70.0
HKD1_k127_971330_17 Phosphoesterase family - - - 0.0000005483 56.0
HKD1_k127_971330_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.016e-263 819.0
HKD1_k127_971330_3 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 589.0
HKD1_k127_971330_4 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 539.0
HKD1_k127_971330_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 467.0
HKD1_k127_971330_6 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 405.0
HKD1_k127_971330_7 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 362.0
HKD1_k127_971330_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 338.0
HKD1_k127_971330_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 311.0