logo

Overview

ID MAG01759
Name HKD1_bin.79
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Blastocatellia
Order Pyrinomonadales
Family Pyrinomonadaceae
Genus UBA11740
Species
Assembly information
Completeness (%) 96.37
Contamination (%) 5.89
GC content (%) 55.0
N50 (bp) 56,442
Genome size (bp) 6,638,180

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4771

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1048226_0 Dienelactone hydrolase family - - - 1.278e-264 838.0
HKD1_k127_1048226_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.898e-249 788.0
HKD1_k127_1048226_10 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 328.0
HKD1_k127_1048226_11 Peptidase, M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005888 284.0
HKD1_k127_1048226_12 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001304 267.0
HKD1_k127_1048226_13 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002863 266.0
HKD1_k127_1048226_14 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003674 278.0
HKD1_k127_1048226_15 region 4 type 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003102 254.0
HKD1_k127_1048226_16 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007771 258.0
HKD1_k127_1048226_17 Pfam:PNPOx_C K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000009281 248.0
HKD1_k127_1048226_18 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000001565 192.0
HKD1_k127_1048226_19 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004567,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010412,GO:0015923,GO:0016052,GO:0016787,GO:0016798,GO:0016985,GO:0016998,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046355,GO:0071554,GO:0071704,GO:1901575 3.2.1.78 0.000000000000000000000000000000000000000000000000001285 205.0
HKD1_k127_1048226_2 PFAM Leukotriene A4 hydrolase, C-terminal - - - 1.933e-223 711.0
HKD1_k127_1048226_20 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000002369 156.0
HKD1_k127_1048226_21 nudix family K01515 - 3.6.1.13 0.0000000000000000000000000000000000004967 147.0
HKD1_k127_1048226_22 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000003793 111.0
HKD1_k127_1048226_23 - - - - 0.000000000000000000000000749 110.0
HKD1_k127_1048226_24 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000002582 105.0
HKD1_k127_1048226_25 Preprotein translocase, YajC subunit K03210 - - 0.00000000000000000003178 93.0
HKD1_k127_1048226_26 Belongs to the UPF0102 family K07460 - - 0.000000000000000005618 90.0
HKD1_k127_1048226_27 TIGRFAM TonB K03832 - - 0.00000000000000003397 91.0
HKD1_k127_1048226_28 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000001593 74.0
HKD1_k127_1048226_29 protein import - - - 0.00000000001989 76.0
HKD1_k127_1048226_3 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 523.0
HKD1_k127_1048226_31 Tetratricopeptide repeat - - - 0.00000005702 64.0
HKD1_k127_1048226_32 peptidase S8 and S53, subtilisin, kexin, sedolisin K14645 - - 0.0000005895 58.0
HKD1_k127_1048226_33 30S ribosomal protein Thx K19033 - - 0.000009944 49.0
HKD1_k127_1048226_4 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 521.0
HKD1_k127_1048226_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 444.0
HKD1_k127_1048226_6 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 432.0
HKD1_k127_1048226_7 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 426.0
HKD1_k127_1048226_8 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 418.0
HKD1_k127_1048226_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 382.0
HKD1_k127_1058044_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 9.749e-218 706.0
HKD1_k127_1058044_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 401.0
HKD1_k127_1058044_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 332.0
HKD1_k127_1058044_3 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001149 287.0
HKD1_k127_1058044_4 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001407 279.0
HKD1_k127_1058044_5 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000001511 197.0
HKD1_k127_1058044_6 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000001136 128.0
HKD1_k127_1058044_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000003788 97.0
HKD1_k127_105957_0 PEP-utilising enzyme, mobile domain - - - 0.0 1047.0
HKD1_k127_105957_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 3.981e-291 913.0
HKD1_k127_105957_10 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 362.0
HKD1_k127_105957_11 Domain of unknown function (DUF1794) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 347.0
HKD1_k127_105957_12 Rnd family efflux transporter mfp subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 324.0
HKD1_k127_105957_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009936 314.0
HKD1_k127_105957_14 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005306 304.0
HKD1_k127_105957_15 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000003759 244.0
HKD1_k127_105957_16 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000001869 222.0
HKD1_k127_105957_17 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000004874 198.0
HKD1_k127_105957_18 Glyoxalase-like domain K08234 - - 0.000000000000000000000000000000000000000000000000000003041 195.0
HKD1_k127_105957_19 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000001088 203.0
HKD1_k127_105957_2 4Fe-4S dicluster domain K00184 - - 1.307e-269 861.0
HKD1_k127_105957_20 Cytochrome c - - - 0.00000000000000000000000000000000000000000000786 168.0
HKD1_k127_105957_21 cytochrome c - - - 0.0000000000000000000000000000000000000001669 156.0
HKD1_k127_105957_22 regulation of RNA biosynthetic process - - - 0.0000000000000000000000000000001593 128.0
HKD1_k127_105957_23 - - - - 0.00000002349 66.0
HKD1_k127_105957_24 Tetratricopeptide repeat - - - 0.000001013 56.0
HKD1_k127_105957_3 protein secretion by the type I secretion system K11085 - - 2.054e-263 826.0
HKD1_k127_105957_4 PFAM Polysulphide reductase, NrfD - - - 1.051e-211 666.0
HKD1_k127_105957_5 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 454.0
HKD1_k127_105957_6 smart pdz dhr glgf K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 436.0
HKD1_k127_105957_7 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 411.0
HKD1_k127_105957_8 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 415.0
HKD1_k127_105957_9 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 394.0
HKD1_k127_1079821_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 465.0
HKD1_k127_1079821_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 342.0
HKD1_k127_1079821_10 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000009666 63.0
HKD1_k127_1079821_11 CHRD domain - - - 0.000007869 60.0
HKD1_k127_1079821_12 PFAM NHL repeat containing protein K13735 - - 0.00001997 59.0
HKD1_k127_1079821_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 302.0
HKD1_k127_1079821_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002129 285.0
HKD1_k127_1079821_4 PFAM Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003637 291.0
HKD1_k127_1079821_5 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005171 271.0
HKD1_k127_1079821_6 PFAM Glycosyl K12994 - 2.4.1.349 0.000000000000000000000000000000000000000000000000000000000008079 221.0
HKD1_k127_1079821_7 PFAM regulatory protein TetR K13770 - - 0.00000000000000000000000000000000000000000000001191 177.0
HKD1_k127_1079821_8 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000004484 131.0
HKD1_k127_1079821_9 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000009871 120.0
HKD1_k127_1080021_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 422.0
HKD1_k127_1080021_10 PA14 - - - 0.0000000000003624 85.0
HKD1_k127_1080021_11 alginic acid biosynthetic process - - - 0.0000000003498 75.0
HKD1_k127_1080021_12 PFAM Fimbrial assembly family protein K02663 - - 0.0000000003951 68.0
HKD1_k127_1080021_13 phosphorelay signal transduction system - - - 0.0000001153 62.0
HKD1_k127_1080021_14 Type II secretory pathway, pseudopilin - - - 0.000001224 58.0
HKD1_k127_1080021_15 Phosphodiester glycosidase - - - 0.00001591 47.0
HKD1_k127_1080021_16 Protein of unknown function (DUF2490) - - - 0.00006996 53.0
HKD1_k127_1080021_17 6-phosphogluconolactonase activity - - - 0.0006931 51.0
HKD1_k127_1080021_2 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 369.0
HKD1_k127_1080021_3 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009666 295.0
HKD1_k127_1080021_4 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006793 287.0
HKD1_k127_1080021_5 Sulfate ABC transporter substrate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000583 226.0
HKD1_k127_1080021_6 Sulfate ABC transporter inner membrane subunit CysW K02047 - - 0.0000000000000000000000000000000000000000000000001836 186.0
HKD1_k127_1080021_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000005397 170.0
HKD1_k127_1080021_8 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000006299 183.0
HKD1_k127_1080021_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000001128 158.0
HKD1_k127_1084478_0 silver ion transport K15726 - - 2.492e-273 875.0
HKD1_k127_1084478_1 ABC transporter transmembrane region K11085 - - 1.036e-242 763.0
HKD1_k127_1084478_10 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 578.0
HKD1_k127_1084478_100 von Willebrand factor, type A - - - 0.0000000000000000006342 99.0
HKD1_k127_1084478_101 Dual specificity phosphatase, catalytic domain - - - 0.0000000000000001084 87.0
HKD1_k127_1084478_102 - - - - 0.0000000000003975 76.0
HKD1_k127_1084478_103 TIGRFAM TonB K03832 - - 0.0000000000005735 79.0
HKD1_k127_1084478_104 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000007057 68.0
HKD1_k127_1084478_105 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000325 74.0
HKD1_k127_1084478_106 gag-polyprotein putative aspartyl protease - - - 0.000000001281 71.0
HKD1_k127_1084478_107 histone H2A K63-linked ubiquitination - - - 0.000000001651 66.0
HKD1_k127_1084478_108 Tetratricopeptide TPR_2 repeat protein - - - 0.000000009843 68.0
HKD1_k127_1084478_109 snoRNA binding - - - 0.00000001294 62.0
HKD1_k127_1084478_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 540.0
HKD1_k127_1084478_110 Peptidoglycan-binding domain 1 protein - - - 0.00000003734 62.0
HKD1_k127_1084478_111 - - - - 0.00000003978 54.0
HKD1_k127_1084478_112 Sh3 type 3 domain protein - - - 0.0000003207 62.0
HKD1_k127_1084478_113 TPM domain K06872 - - 0.0000003435 64.0
HKD1_k127_1084478_114 - - - - 0.0000006864 51.0
HKD1_k127_1084478_116 Domain of unknown function (DUF4190) - - - 0.000002418 57.0
HKD1_k127_1084478_117 - K01387,K06399 - 3.4.21.116,3.4.24.3 0.00002538 57.0
HKD1_k127_1084478_118 methyltransferase - - - 0.0001164 55.0
HKD1_k127_1084478_12 Glycosyl hydrolase family 47 K01230 - 3.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 537.0
HKD1_k127_1084478_120 Transposase IS200 like - - - 0.0006651 42.0
HKD1_k127_1084478_13 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 542.0
HKD1_k127_1084478_14 Aminotransferase class-III K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 531.0
HKD1_k127_1084478_15 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 519.0
HKD1_k127_1084478_16 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 503.0
HKD1_k127_1084478_17 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 485.0
HKD1_k127_1084478_18 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 460.0
HKD1_k127_1084478_19 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 466.0
HKD1_k127_1084478_2 Heat shock 70 kDa protein K04043 - - 7.194e-230 726.0
HKD1_k127_1084478_20 PQQ-like domain K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 453.0
HKD1_k127_1084478_21 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 421.0
HKD1_k127_1084478_22 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 402.0
HKD1_k127_1084478_23 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 404.0
HKD1_k127_1084478_24 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 394.0
HKD1_k127_1084478_25 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 378.0
HKD1_k127_1084478_26 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 366.0
HKD1_k127_1084478_27 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 352.0
HKD1_k127_1084478_28 Neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 343.0
HKD1_k127_1084478_29 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 347.0
HKD1_k127_1084478_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 9.109e-201 647.0
HKD1_k127_1084478_30 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 362.0
HKD1_k127_1084478_31 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 332.0
HKD1_k127_1084478_33 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 317.0
HKD1_k127_1084478_34 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 319.0
HKD1_k127_1084478_35 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 337.0
HKD1_k127_1084478_36 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 329.0
HKD1_k127_1084478_37 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 321.0
HKD1_k127_1084478_38 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 298.0
HKD1_k127_1084478_39 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 286.0
HKD1_k127_1084478_4 Ribosomal protein S1 K02945 - - 1.397e-198 636.0
HKD1_k127_1084478_40 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002821 282.0
HKD1_k127_1084478_41 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003973 282.0
HKD1_k127_1084478_42 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001585 293.0
HKD1_k127_1084478_43 7TM receptor with intracellular metal dependent phosphohydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001364 280.0
HKD1_k127_1084478_44 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001621 265.0
HKD1_k127_1084478_45 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000003338 275.0
HKD1_k127_1084478_46 Domain of unknown function (DUF3471) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 270.0
HKD1_k127_1084478_47 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001115 260.0
HKD1_k127_1084478_48 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002456 276.0
HKD1_k127_1084478_49 PFAM phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004037 267.0
HKD1_k127_1084478_5 Zinc-binding dehydrogenase - - - 2.158e-195 633.0
HKD1_k127_1084478_50 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000004673 247.0
HKD1_k127_1084478_51 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000002562 245.0
HKD1_k127_1084478_52 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000006991 239.0
HKD1_k127_1084478_53 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000007676 232.0
HKD1_k127_1084478_54 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000005307 233.0
HKD1_k127_1084478_55 - - - - 0.000000000000000000000000000000000000000000000000000000000000006741 230.0
HKD1_k127_1084478_56 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000006985 220.0
HKD1_k127_1084478_57 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000002217 219.0
HKD1_k127_1084478_58 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000001523 215.0
HKD1_k127_1084478_59 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000004162 214.0
HKD1_k127_1084478_6 MviN-like protein K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 601.0
HKD1_k127_1084478_60 Disulphide isomerase - - - 0.00000000000000000000000000000000000000000000000000005541 190.0
HKD1_k127_1084478_61 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000001028 190.0
HKD1_k127_1084478_62 nucleotide metabolic process - - - 0.0000000000000000000000000000000000000000000000000001221 196.0
HKD1_k127_1084478_63 NDK K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000268 188.0
HKD1_k127_1084478_64 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000008154 191.0
HKD1_k127_1084478_65 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000007 192.0
HKD1_k127_1084478_66 Membrane - - - 0.00000000000000000000000000000000000000000000002601 194.0
HKD1_k127_1084478_67 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000005215 192.0
HKD1_k127_1084478_68 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000001685 173.0
HKD1_k127_1084478_69 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000000000001732 174.0
HKD1_k127_1084478_7 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 594.0
HKD1_k127_1084478_70 SMART tyrosine protein kinase - - - 0.00000000000000000000000000000000000000000001158 177.0
HKD1_k127_1084478_71 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000004706 163.0
HKD1_k127_1084478_72 Putative lumazine-binding - - - 0.00000000000000000000000000000000000000000007535 164.0
HKD1_k127_1084478_73 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000001227 169.0
HKD1_k127_1084478_74 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000002838 167.0
HKD1_k127_1084478_75 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.00000000000000000000000000000000000000009253 158.0
HKD1_k127_1084478_76 Peptidase family M50 K06402 - - 0.00000000000000000000000000000000000003513 152.0
HKD1_k127_1084478_77 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.00000000000000000000000000000000000005326 149.0
HKD1_k127_1084478_78 Peptidase S1 and S6 chymotrypsin Hap - - - 0.0000000000000000000000000000000000003489 154.0
HKD1_k127_1084478_79 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000000000000000001588 140.0
HKD1_k127_1084478_8 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 602.0
HKD1_k127_1084478_80 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000007443 141.0
HKD1_k127_1084478_81 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01838 - 5.4.2.6 0.00000000000000000000000000000000108 140.0
HKD1_k127_1084478_82 protein conserved in bacteria - - - 0.000000000000000000000000000000009167 134.0
HKD1_k127_1084478_83 MgtC SapB transporter K07507 - - 0.0000000000000000000000000000003652 130.0
HKD1_k127_1084478_84 regulation of translation K05788 - - 0.00000000000000000000000000002133 119.0
HKD1_k127_1084478_85 peptidase inhibitor activity - - - 0.0000000000000000000000000005418 124.0
HKD1_k127_1084478_86 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000000008171 122.0
HKD1_k127_1084478_87 - - - - 0.000000000000000000000000005154 120.0
HKD1_k127_1084478_88 PFAM Outer membrane efflux protein K15725 - - 0.00000000000000000000000004344 123.0
HKD1_k127_1084478_89 peptidase inhibitor activity - - - 0.00000000000000000000000007628 119.0
HKD1_k127_1084478_9 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 566.0
HKD1_k127_1084478_91 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000008289 111.0
HKD1_k127_1084478_92 Pfam:DUF1311 - - - 0.0000000000000000000000009877 108.0
HKD1_k127_1084478_93 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.000000000000000000000001483 108.0
HKD1_k127_1084478_94 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000000000002557 117.0
HKD1_k127_1084478_95 PIN domain - - - 0.00000000000000000000001531 107.0
HKD1_k127_1084478_96 - - - - 0.00000000000000000000003739 100.0
HKD1_k127_1084478_98 tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.0000000000000000000001335 103.0
HKD1_k127_1084478_99 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000002982 113.0
HKD1_k127_1086117_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1229.0
HKD1_k127_1086117_1 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 425.0
HKD1_k127_1086117_10 DoxX - - - 0.000000000000000000000000000000000000000000000000000000004485 203.0
HKD1_k127_1086117_11 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000128 146.0
HKD1_k127_1086117_12 Transposase and inactivated derivatives - - - 0.0005763 44.0
HKD1_k127_1086117_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 413.0
HKD1_k127_1086117_3 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 409.0
HKD1_k127_1086117_4 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 389.0
HKD1_k127_1086117_5 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 389.0
HKD1_k127_1086117_6 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 326.0
HKD1_k127_1086117_7 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002694 276.0
HKD1_k127_1086117_8 Pfam Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007303 262.0
HKD1_k127_1086117_9 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001093 224.0
HKD1_k127_1099284_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0 1791.0
HKD1_k127_1099284_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 8.914e-310 971.0
HKD1_k127_1099284_10 dihydroorotate dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 551.0
HKD1_k127_1099284_11 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 526.0
HKD1_k127_1099284_12 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 505.0
HKD1_k127_1099284_13 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 480.0
HKD1_k127_1099284_14 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 470.0
HKD1_k127_1099284_15 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 440.0
HKD1_k127_1099284_16 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 421.0
HKD1_k127_1099284_17 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 376.0
HKD1_k127_1099284_18 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 352.0
HKD1_k127_1099284_19 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 343.0
HKD1_k127_1099284_2 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 5.509e-226 709.0
HKD1_k127_1099284_20 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 343.0
HKD1_k127_1099284_21 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 331.0
HKD1_k127_1099284_22 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 338.0
HKD1_k127_1099284_23 Putative cyclase K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 322.0
HKD1_k127_1099284_24 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 291.0
HKD1_k127_1099284_25 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 292.0
HKD1_k127_1099284_26 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000257 249.0
HKD1_k127_1099284_27 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000005921 226.0
HKD1_k127_1099284_28 - - - - 0.000000000000000000000000000000000000000000000000001412 190.0
HKD1_k127_1099284_29 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000487 183.0
HKD1_k127_1099284_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.318e-221 701.0
HKD1_k127_1099284_30 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000000000000000000002906 183.0
HKD1_k127_1099284_31 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000227 170.0
HKD1_k127_1099284_32 Cytochrome c - - - 0.000000000000000000000000000000000000000000003704 175.0
HKD1_k127_1099284_33 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000007359 122.0
HKD1_k127_1099284_34 Methyltransferase - - - 0.00000000000000000000000001158 119.0
HKD1_k127_1099284_35 Polysaccharide deacetylase - - - 0.00000000000000000000000008174 117.0
HKD1_k127_1099284_36 gamma-carboxymuconolactone decarboxylase subunit - - - 0.0000000000000000000000001132 110.0
HKD1_k127_1099284_37 response regulator K07782,K15852 - - 0.000000000000000000000004231 110.0
HKD1_k127_1099284_38 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000009769 102.0
HKD1_k127_1099284_39 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000003713 98.0
HKD1_k127_1099284_4 Helix-hairpin-helix motif K14162 - 2.7.7.7 4.206e-214 707.0
HKD1_k127_1099284_40 Tetratricopeptide repeat - - - 0.0000000000005043 81.0
HKD1_k127_1099284_5 Pyridoxal-phosphate dependent enzyme K01738,K01912 - 2.5.1.47,6.2.1.30 9.197e-195 618.0
HKD1_k127_1099284_6 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.411e-194 634.0
HKD1_k127_1099284_7 Belongs to the ATCase OTCase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 543.0
HKD1_k127_1099284_8 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 541.0
HKD1_k127_1099284_9 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 542.0
HKD1_k127_111006_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2101.0
HKD1_k127_111006_1 Carboxypeptidase regulatory-like domain - - - 0.0 1104.0
HKD1_k127_111006_10 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 347.0
HKD1_k127_111006_11 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 337.0
HKD1_k127_111006_12 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 348.0
HKD1_k127_111006_13 Ornithine cyclodeaminase/mu-crystallin family K21721 - 1.5.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 325.0
HKD1_k127_111006_14 Peptidase family S51 K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008501 281.0
HKD1_k127_111006_15 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001928 304.0
HKD1_k127_111006_16 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001013 291.0
HKD1_k127_111006_17 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007773 260.0
HKD1_k127_111006_18 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005315 250.0
HKD1_k127_111006_19 Chromate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005358 252.0
HKD1_k127_111006_2 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 3.523e-276 857.0
HKD1_k127_111006_20 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000006424 239.0
HKD1_k127_111006_21 4fe-4S ferredoxin, iron-sulfur binding domain protein K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000006625 235.0
HKD1_k127_111006_22 cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000001084 224.0
HKD1_k127_111006_23 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000003695 239.0
HKD1_k127_111006_24 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000005485 229.0
HKD1_k127_111006_25 PFAM TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000000000000000000000000000000006967 231.0
HKD1_k127_111006_26 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000007008 166.0
HKD1_k127_111006_27 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000005128 153.0
HKD1_k127_111006_28 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000001164 167.0
HKD1_k127_111006_29 PFAM Proprotein convertase P-domain - - - 0.0000000000000000000001241 116.0
HKD1_k127_111006_3 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 6.011e-224 704.0
HKD1_k127_111006_30 Polymorphic membrane protein, Chlamydia - - - 0.0000000000000000000003725 115.0
HKD1_k127_111006_31 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000003209 108.0
HKD1_k127_111006_32 Polymorphic membrane protein, Chlamydia - - - 0.000000000000000001846 103.0
HKD1_k127_111006_33 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000001858 82.0
HKD1_k127_111006_34 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000003053 76.0
HKD1_k127_111006_35 heat shock protein binding - - - 0.0000001292 63.0
HKD1_k127_111006_36 Cytochrome c7 and related cytochrome c - - - 0.000000511 62.0
HKD1_k127_111006_37 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000008881 55.0
HKD1_k127_111006_38 PFAM cytochrome c class III - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000008434 58.0
HKD1_k127_111006_39 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00005856 55.0
HKD1_k127_111006_4 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 2.365e-213 672.0
HKD1_k127_111006_40 PFAM cytochrome c class III - - - 0.0004214 50.0
HKD1_k127_111006_5 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 3.835e-198 633.0
HKD1_k127_111006_6 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 583.0
HKD1_k127_111006_7 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 469.0
HKD1_k127_111006_8 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 430.0
HKD1_k127_111006_9 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 390.0
HKD1_k127_1122818_0 Carboxypeptidase regulatory-like domain - - - 0.0 1056.0
HKD1_k127_1122818_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 1.923e-261 818.0
HKD1_k127_1122818_10 SnoaL-like domain - - - 0.0000000118 59.0
HKD1_k127_1122818_11 PFAM HPr Serine kinase C-terminal domain - - - 0.0001391 53.0
HKD1_k127_1122818_2 Heparinase II/III-like protein - - - 2.321e-227 724.0
HKD1_k127_1122818_3 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 530.0
HKD1_k127_1122818_4 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 428.0
HKD1_k127_1122818_5 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000001386 249.0
HKD1_k127_1122818_6 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000115 242.0
HKD1_k127_1122818_7 asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000001664 145.0
HKD1_k127_1122818_8 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000006317 106.0
HKD1_k127_1122818_9 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000736 88.0
HKD1_k127_1137008_0 PFAM acyl-CoA dehydrogenase domain protein - - - 1.33e-196 626.0
HKD1_k127_1137008_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 374.0
HKD1_k127_1137008_2 Transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005853 284.0
HKD1_k127_1137008_3 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.000000000157 69.0
HKD1_k127_1137008_4 - - - - 0.00001373 56.0
HKD1_k127_1152682_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 6.353e-301 944.0
HKD1_k127_1152682_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 8.695e-265 831.0
HKD1_k127_1152682_10 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 371.0
HKD1_k127_1152682_11 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 352.0
HKD1_k127_1152682_12 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 332.0
HKD1_k127_1152682_13 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 325.0
HKD1_k127_1152682_14 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 314.0
HKD1_k127_1152682_15 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000339 275.0
HKD1_k127_1152682_16 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001073 277.0
HKD1_k127_1152682_17 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000024 269.0
HKD1_k127_1152682_18 Protein of unknown function (DUF354) K09726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002209 255.0
HKD1_k127_1152682_19 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.000000000000000000000000000000000000000000000000000000000000000000163 235.0
HKD1_k127_1152682_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 3.036e-254 812.0
HKD1_k127_1152682_20 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003614 235.0
HKD1_k127_1152682_21 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.000000000000000000000000000000000000000000000000000000000000000001358 236.0
HKD1_k127_1152682_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005812 235.0
HKD1_k127_1152682_23 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000003454 226.0
HKD1_k127_1152682_24 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000007274 230.0
HKD1_k127_1152682_25 Transcription factor zinc-finger - - - 0.000000000000000000000000000000000000000000000000000000000000007928 223.0
HKD1_k127_1152682_26 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.0000000000000000000000000000000000000000000000000000000000004355 222.0
HKD1_k127_1152682_27 PFAM Peptidase M20 - - - 0.0000000000000000000000000000000000000000000000000000000008665 217.0
HKD1_k127_1152682_28 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.000000000000000000000000000000000000000000000000000000001239 207.0
HKD1_k127_1152682_29 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000001729 213.0
HKD1_k127_1152682_3 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 1.1e-221 700.0
HKD1_k127_1152682_30 - - - - 0.0000000000000000000000000000000000000000000000000001187 188.0
HKD1_k127_1152682_31 - - - - 0.000000000000000000000000000000000000000000000000002889 186.0
HKD1_k127_1152682_32 Domain of unknown function (DUF1990) - - - 0.00000000000000000000000000000000000000000003134 167.0
HKD1_k127_1152682_33 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000003914 158.0
HKD1_k127_1152682_34 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000009122 158.0
HKD1_k127_1152682_35 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000002283 147.0
HKD1_k127_1152682_36 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000000000000000000005282 143.0
HKD1_k127_1152682_37 Thiol-disulfide oxidoreductase - - - 0.00000000000000000000000000000001828 130.0
HKD1_k127_1152682_38 IPT/TIG domain - - - 0.00000000000000000000000003723 124.0
HKD1_k127_1152682_39 Protein conserved in bacteria - - - 0.0000000000000000000000000405 112.0
HKD1_k127_1152682_4 benzoyl-CoA oxygenase K15512 - 1.14.13.208 4.01e-212 668.0
HKD1_k127_1152682_40 - - - - 0.0000000000000000000000005708 109.0
HKD1_k127_1152682_41 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.0000000000000000000002179 102.0
HKD1_k127_1152682_42 O-Antigen ligase K18814 - - 0.00000000000000000006717 104.0
HKD1_k127_1152682_43 Lipopolysaccharide-assembly - - - 0.0000000000000002585 86.0
HKD1_k127_1152682_44 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000001108 79.0
HKD1_k127_1152682_45 Modulates RecA activity K03565 - - 0.0000000004044 68.0
HKD1_k127_1152682_46 - - - - 0.00000002835 66.0
HKD1_k127_1152682_47 - - - - 0.0000001218 63.0
HKD1_k127_1152682_48 - - - - 0.0000002608 64.0
HKD1_k127_1152682_5 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 607.0
HKD1_k127_1152682_6 coenzyme binding K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 454.0
HKD1_k127_1152682_7 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 402.0
HKD1_k127_1152682_8 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 391.0
HKD1_k127_1152682_9 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 370.0
HKD1_k127_1165975_0 transport - - - 0.0 1405.0
HKD1_k127_1165975_1 PFAM Cna B domain protein - - - 0.0 1305.0
HKD1_k127_1165975_10 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 492.0
HKD1_k127_1165975_11 symporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 463.0
HKD1_k127_1165975_12 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 452.0
HKD1_k127_1165975_13 Periplasmic binding protein domain K02058,K10543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 402.0
HKD1_k127_1165975_14 carbohydrate transport K10544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 385.0
HKD1_k127_1165975_15 4Fe-4S binding domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 374.0
HKD1_k127_1165975_16 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 304.0
HKD1_k127_1165975_17 Amidohydrolase family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000569 265.0
HKD1_k127_1165975_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000007158 226.0
HKD1_k127_1165975_19 Aminotransferase, class V - - - 0.000000000000000000000000000000000000000000000000000003255 205.0
HKD1_k127_1165975_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.204e-262 824.0
HKD1_k127_1165975_20 BadF BadG BcrA BcrD - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000011 164.0
HKD1_k127_1165975_21 Glycosyl hydrolase-like 10 - - - 0.0000000000000000000000000000000000000001336 168.0
HKD1_k127_1165975_22 LysR substrate binding domain K21703,K21711 - - 0.0000000000000000000000000000000000001233 153.0
HKD1_k127_1165975_23 FR47-like protein - - - 0.00000000000000000000000000000004753 132.0
HKD1_k127_1165975_24 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000000000002445 124.0
HKD1_k127_1165975_25 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000000000000005054 97.0
HKD1_k127_1165975_26 - - - - 0.000000001659 64.0
HKD1_k127_1165975_27 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000002141 57.0
HKD1_k127_1165975_28 PFAM YcfA family protein - - - 0.00000008111 53.0
HKD1_k127_1165975_29 Aminotransferase class I and II K00375 - - 0.0000009537 55.0
HKD1_k127_1165975_3 beta-lactamase - - - 6.671e-252 805.0
HKD1_k127_1165975_4 TonB-dependent Receptor Plug - - - 1.289e-239 783.0
HKD1_k127_1165975_5 Prolyl oligopeptidase family - - - 9.434e-212 677.0
HKD1_k127_1165975_6 Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system K10441,K10545 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 579.0
HKD1_k127_1165975_7 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 560.0
HKD1_k127_1165975_8 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 516.0
HKD1_k127_1165975_9 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 496.0
HKD1_k127_1195810_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 313.0
HKD1_k127_1195810_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 298.0
HKD1_k127_1195810_2 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000006818 218.0
HKD1_k127_1202392_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 551.0
HKD1_k127_1202392_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 486.0
HKD1_k127_1202392_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 289.0
HKD1_k127_1202392_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000002131 205.0
HKD1_k127_1202392_4 MMPL family K07003 - - 0.0000000000000000000000000001277 129.0
HKD1_k127_1238966_0 Carboxypeptidase regulatory-like domain - - - 1.424e-293 940.0
HKD1_k127_1238966_1 Belongs to the binding-protein-dependent transport system permease family K10559,K10561 - - 7.909e-269 844.0
HKD1_k127_1238966_10 Transposase IS200 like - - - 0.000729 44.0
HKD1_k127_1238966_2 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 3.259e-196 627.0
HKD1_k127_1238966_3 Xylose isomerase-like TIM barrel K01820 - 5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 537.0
HKD1_k127_1238966_4 Oligogalacturonate lyase K01730 - 4.2.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 485.0
HKD1_k127_1238966_5 TIGRFAM iron-sulfur cluster binding protein K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 467.0
HKD1_k127_1238966_6 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate K00848 - 2.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 411.0
HKD1_k127_1238966_7 Branched-chain amino acid transport system / permease component K10560 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 327.0
HKD1_k127_1238966_8 Involved in the anomeric conversion of L-rhamnose K03534 - 5.1.3.32 0.0000000000000000000000000000000001085 139.0
HKD1_k127_1238966_9 LUD domain K00782 - - 0.000000000000000000000001379 112.0
HKD1_k127_1252583_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 3.418e-240 758.0
HKD1_k127_1252583_1 glutamine synthetase K01915 - 6.3.1.2 3.77e-209 659.0
HKD1_k127_1252583_10 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 423.0
HKD1_k127_1252583_11 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 395.0
HKD1_k127_1252583_12 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 316.0
HKD1_k127_1252583_13 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 309.0
HKD1_k127_1252583_14 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004967 287.0
HKD1_k127_1252583_15 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000172 277.0
HKD1_k127_1252583_16 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000002519 275.0
HKD1_k127_1252583_17 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000006369 256.0
HKD1_k127_1252583_18 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007389 248.0
HKD1_k127_1252583_19 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000004539 238.0
HKD1_k127_1252583_2 Calcineurin-like phosphoesterase - - - 8.813e-199 642.0
HKD1_k127_1252583_20 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000002571 239.0
HKD1_k127_1252583_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006774 244.0
HKD1_k127_1252583_22 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000002626 222.0
HKD1_k127_1252583_23 aminotransferase K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000008612 234.0
HKD1_k127_1252583_24 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000114 222.0
HKD1_k127_1252583_25 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000005042 228.0
HKD1_k127_1252583_26 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000004801 215.0
HKD1_k127_1252583_27 Transport permease protein K09690 - - 0.00000000000000000000000000000000000000000000000000000000001245 216.0
HKD1_k127_1252583_28 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000008023 226.0
HKD1_k127_1252583_29 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000005957 198.0
HKD1_k127_1252583_3 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 587.0
HKD1_k127_1252583_30 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000006949 188.0
HKD1_k127_1252583_31 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000003626 189.0
HKD1_k127_1252583_32 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000309 189.0
HKD1_k127_1252583_33 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000004369 184.0
HKD1_k127_1252583_34 Phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000002818 189.0
HKD1_k127_1252583_35 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000001763 179.0
HKD1_k127_1252583_37 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000008115 174.0
HKD1_k127_1252583_38 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000002632 170.0
HKD1_k127_1252583_39 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000000000002597 165.0
HKD1_k127_1252583_4 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 568.0
HKD1_k127_1252583_40 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000001413 154.0
HKD1_k127_1252583_41 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.0000000000000000000000000000000000001627 149.0
HKD1_k127_1252583_42 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000005463 143.0
HKD1_k127_1252583_43 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000003296 133.0
HKD1_k127_1252583_44 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000551 140.0
HKD1_k127_1252583_45 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000009118 132.0
HKD1_k127_1252583_46 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000002356 127.0
HKD1_k127_1252583_47 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000003068 131.0
HKD1_k127_1252583_48 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000001716 123.0
HKD1_k127_1252583_49 Tetratricopeptide repeat - - - 0.00000000000000000000000000002814 132.0
HKD1_k127_1252583_5 COG2303 Choline dehydrogenase and related flavoproteins K03333 - 1.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 537.0
HKD1_k127_1252583_50 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000008733 115.0
HKD1_k127_1252583_51 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000001964 119.0
HKD1_k127_1252583_52 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000003248 117.0
HKD1_k127_1252583_53 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000003249 113.0
HKD1_k127_1252583_54 structural constituent of ribosome K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000002015 115.0
HKD1_k127_1252583_55 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000002556 110.0
HKD1_k127_1252583_56 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000003333 102.0
HKD1_k127_1252583_57 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000008015 106.0
HKD1_k127_1252583_58 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000003969 98.0
HKD1_k127_1252583_59 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000006243 95.0
HKD1_k127_1252583_6 threonine synthase activity K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 499.0
HKD1_k127_1252583_60 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001558 74.0
HKD1_k127_1252583_61 Ribosomal protein L30 K02907 - - 0.00000000000003936 75.0
HKD1_k127_1252583_62 helix_turn_helix, Lux Regulon - - - 0.0000000004305 68.0
HKD1_k127_1252583_63 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.000000004202 59.0
HKD1_k127_1252583_64 - - - - 0.000000005748 63.0
HKD1_k127_1252583_66 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000143 51.0
HKD1_k127_1252583_67 Ribosomal L29 protein K02904 - - 0.0005067 45.0
HKD1_k127_1252583_68 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0008567 50.0
HKD1_k127_1252583_7 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 499.0
HKD1_k127_1252583_8 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 473.0
HKD1_k127_1252583_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 466.0
HKD1_k127_1270891_0 Amino acid adenylation domain - - - 0.0 1235.0
HKD1_k127_1270891_1 iron-nicotianamine transmembrane transporter activity - - - 4.725e-287 904.0
HKD1_k127_1270891_10 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000005029 208.0
HKD1_k127_1270891_11 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000001081 187.0
HKD1_k127_1270891_12 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000004372 185.0
HKD1_k127_1270891_13 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000125 176.0
HKD1_k127_1270891_14 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000000001529 156.0
HKD1_k127_1270891_15 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000002973 153.0
HKD1_k127_1270891_16 WD40 domain protein beta Propeller K03641 - - 0.000000000000000000000000000000002124 136.0
HKD1_k127_1270891_17 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000002076 126.0
HKD1_k127_1270891_18 enzyme binding K00567,K07443 - 2.1.1.63 0.00000000000000000000001133 105.0
HKD1_k127_1270891_19 PFAM WD40 domain protein beta Propeller - - - 0.000000000000000005059 90.0
HKD1_k127_1270891_2 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 594.0
HKD1_k127_1270891_20 - - - - 0.00000000000000003541 87.0
HKD1_k127_1270891_22 Thioesterase superfamily - - - 0.0000000002476 67.0
HKD1_k127_1270891_23 Protein of unknown function (DUF2950) - - - 0.0001936 52.0
HKD1_k127_1270891_3 (ABC) transporter K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 591.0
HKD1_k127_1270891_4 ABC transporter, transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 578.0
HKD1_k127_1270891_5 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 570.0
HKD1_k127_1270891_6 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009172 554.0
HKD1_k127_1270891_7 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 454.0
HKD1_k127_1270891_8 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 450.0
HKD1_k127_1270891_9 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 437.0
HKD1_k127_1326452_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 583.0
HKD1_k127_1326452_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 540.0
HKD1_k127_1326452_10 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 325.0
HKD1_k127_1326452_11 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000268 279.0
HKD1_k127_1326452_12 Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006526 268.0
HKD1_k127_1326452_13 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000006233 227.0
HKD1_k127_1326452_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000001257 215.0
HKD1_k127_1326452_15 ) H( ) antiporter that extrudes sodium in exchange for external protons - - - 0.000000000000000000000000000000000000003105 154.0
HKD1_k127_1326452_16 triphosphatase activity - - - 0.0000000000000000000002349 104.0
HKD1_k127_1326452_17 Protein of unknown function (DUF3298) - - - 0.0000000000000000000003246 109.0
HKD1_k127_1326452_18 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000002722 95.0
HKD1_k127_1326452_19 transcriptional regulator - - - 0.000000000000000000009444 97.0
HKD1_k127_1326452_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 425.0
HKD1_k127_1326452_20 Protein of unknown function (DUF2905) - - - 0.000000000000002138 80.0
HKD1_k127_1326452_21 Domain of unknown function (DUF4870) - - - 0.000000000000004228 81.0
HKD1_k127_1326452_23 TM2 domain - - - 0.000000000006163 71.0
HKD1_k127_1326452_24 Protein of unknown function (DUF4019) - - - 0.00003266 51.0
HKD1_k127_1326452_25 Carboxypeptidase regulatory-like domain - - - 0.00006033 56.0
HKD1_k127_1326452_26 Sigma-70 region 3 K02405,K03090 - - 0.00006791 54.0
HKD1_k127_1326452_27 PFAM Vitamin K epoxide reductase - - - 0.0001133 50.0
HKD1_k127_1326452_28 TPM domain K06872 - - 0.0003382 52.0
HKD1_k127_1326452_3 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 412.0
HKD1_k127_1326452_4 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 383.0
HKD1_k127_1326452_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 367.0
HKD1_k127_1326452_6 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 352.0
HKD1_k127_1326452_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 348.0
HKD1_k127_1326452_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 322.0
HKD1_k127_1326452_9 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 342.0
HKD1_k127_1390984_0 hydrolase, family 3 K05349 - 3.2.1.21 0.0 1210.0
HKD1_k127_1390984_1 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0 1069.0
HKD1_k127_1390984_10 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 577.0
HKD1_k127_1390984_11 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 546.0
HKD1_k127_1390984_12 glucuronate isomerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 469.0
HKD1_k127_1390984_13 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 441.0
HKD1_k127_1390984_14 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007271 290.0
HKD1_k127_1390984_15 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000002126 160.0
HKD1_k127_1390984_16 MFS/sugar transport protein - - - 0.00000000000000000000000000001439 121.0
HKD1_k127_1390984_17 Transposase K07491 - - 0.0002643 43.0
HKD1_k127_1390984_2 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 6.047e-298 930.0
HKD1_k127_1390984_3 Belongs to the glycosyl hydrolase 43 family K01198 - 3.2.1.37 5.999e-293 906.0
HKD1_k127_1390984_4 Glycosyl Hydrolase Family 88 - - - 2.66e-232 726.0
HKD1_k127_1390984_5 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 1.386e-226 715.0
HKD1_k127_1390984_6 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01706 - 4.2.1.40 1.168e-221 692.0
HKD1_k127_1390984_7 Peptidase dimerisation domain - - - 4.826e-209 662.0
HKD1_k127_1390984_8 PFAM Major Facilitator Superfamily K08191 - - 1.434e-204 646.0
HKD1_k127_1390984_9 Ammonium Transporter K03320 - - 4.426e-204 646.0
HKD1_k127_1403771_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1743.0
HKD1_k127_1403771_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1142.0
HKD1_k127_1403771_10 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 522.0
HKD1_k127_1403771_11 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 506.0
HKD1_k127_1403771_12 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 474.0
HKD1_k127_1403771_13 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 469.0
HKD1_k127_1403771_14 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 484.0
HKD1_k127_1403771_15 Belongs to the allantoicase family K01477 - 3.5.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 455.0
HKD1_k127_1403771_16 nitrite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 458.0
HKD1_k127_1403771_17 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 450.0
HKD1_k127_1403771_18 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 452.0
HKD1_k127_1403771_19 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 454.0
HKD1_k127_1403771_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 3.405e-283 888.0
HKD1_k127_1403771_20 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 444.0
HKD1_k127_1403771_21 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 452.0
HKD1_k127_1403771_22 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 415.0
HKD1_k127_1403771_23 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 412.0
HKD1_k127_1403771_24 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 396.0
HKD1_k127_1403771_25 Strictosidine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 360.0
HKD1_k127_1403771_26 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 319.0
HKD1_k127_1403771_27 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 317.0
HKD1_k127_1403771_28 Protein of unknown function (DUF434) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 294.0
HKD1_k127_1403771_29 4 iron, 4 sulfur cluster binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 293.0
HKD1_k127_1403771_3 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 7.318e-272 854.0
HKD1_k127_1403771_30 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 283.0
HKD1_k127_1403771_31 Uncharacterised ACR (DUF711) K09157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003302 275.0
HKD1_k127_1403771_32 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000006053 258.0
HKD1_k127_1403771_33 Domain of unknown function (DUF4287) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003132 246.0
HKD1_k127_1403771_34 Domain of Unknown function (DUF542) K07322 - - 0.00000000000000000000000000000000000000000000000000000000000000001325 231.0
HKD1_k127_1403771_35 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000001324 251.0
HKD1_k127_1403771_36 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.000000000000000000000000000000000000000000000000000000000000002627 222.0
HKD1_k127_1403771_37 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000973 223.0
HKD1_k127_1403771_38 surface antigen variable number - - - 0.0000000000000000000000000000000000000000000000000000000000001851 243.0
HKD1_k127_1403771_39 Riboflavin synthase K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000008197 213.0
HKD1_k127_1403771_4 GTP-binding protein TypA K06207 - - 2.335e-256 803.0
HKD1_k127_1403771_40 NnrS protein - - - 0.00000000000000000000000000000000000000000000000000000000003248 223.0
HKD1_k127_1403771_41 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000454 209.0
HKD1_k127_1403771_42 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000001352 203.0
HKD1_k127_1403771_43 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000001926 196.0
HKD1_k127_1403771_44 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000000000000000000000000000000000002479 187.0
HKD1_k127_1403771_45 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000004114 173.0
HKD1_k127_1403771_46 - - - - 0.0000000000000000000000000000000000000000000002094 191.0
HKD1_k127_1403771_47 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000000000005329 172.0
HKD1_k127_1403771_48 protein secretion K09800 - - 0.000000000000000000000000000000000000000000319 184.0
HKD1_k127_1403771_49 SET domain K07117 - - 0.000000000000000000000000000000000000000001012 160.0
HKD1_k127_1403771_5 Tetratricopeptide repeat - - - 5.68e-200 639.0
HKD1_k127_1403771_50 cyclic nucleotide-binding K01420,K10914 - - 0.000000000000000000000000000000000000000003016 164.0
HKD1_k127_1403771_51 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000007011 154.0
HKD1_k127_1403771_52 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000007415 154.0
HKD1_k127_1403771_53 PFAM glycine cleavage H-protein - - - 0.000000000000000000000000000000000000009745 155.0
HKD1_k127_1403771_54 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000001702 142.0
HKD1_k127_1403771_55 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000003184 140.0
HKD1_k127_1403771_56 - - - - 0.00000000000000000000000000000000004925 139.0
HKD1_k127_1403771_57 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000000000000000000000000000009532 131.0
HKD1_k127_1403771_58 membrane - - - 0.000000000000000000000000000001635 123.0
HKD1_k127_1403771_59 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000002026 125.0
HKD1_k127_1403771_6 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 578.0
HKD1_k127_1403771_60 Universal stress protein family - - - 0.000000000000000000000000001305 117.0
HKD1_k127_1403771_61 Glycine cleavage H-protein - - - 0.00000000000000000000000000319 120.0
HKD1_k127_1403771_63 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.000000000000000000000001954 109.0
HKD1_k127_1403771_64 Thioesterase superfamily K07107 - - 0.000000000000000000000003659 107.0
HKD1_k127_1403771_65 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000002997 105.0
HKD1_k127_1403771_66 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000005181 109.0
HKD1_k127_1403771_67 - - - - 0.000000000000000000001058 108.0
HKD1_k127_1403771_68 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000001197 110.0
HKD1_k127_1403771_69 serine threonine protein kinase - - - 0.000000000000000000002036 100.0
HKD1_k127_1403771_7 Amidohydrolase family K01466 - 3.5.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 548.0
HKD1_k127_1403771_70 Ferredoxin - - - 0.000000000000000000007461 95.0
HKD1_k127_1403771_71 - - - - 0.00000000000000001238 84.0
HKD1_k127_1403771_72 - - - - 0.0000000000001598 76.0
HKD1_k127_1403771_73 Anti-sigma-K factor rskA - - - 0.0000000000006314 78.0
HKD1_k127_1403771_74 heme-binding sites - - - 0.00000000005874 74.0
HKD1_k127_1403771_76 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.0000000006524 67.0
HKD1_k127_1403771_77 Protein of unknown function (DUF983) - - - 0.000000000973 67.0
HKD1_k127_1403771_78 Domain of unknown function (DUF4149) - - - 0.000000001427 65.0
HKD1_k127_1403771_79 Domain of unknown function (DUF309) - - - 0.000000001559 64.0
HKD1_k127_1403771_8 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 558.0
HKD1_k127_1403771_80 peptidyl-tyrosine sulfation - - - 0.000001837 61.0
HKD1_k127_1403771_81 protein kinase activity - - - 0.000004811 54.0
HKD1_k127_1403771_82 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000007906 56.0
HKD1_k127_1403771_84 12 heme-binding sites - - - 0.00002948 57.0
HKD1_k127_1403771_85 Zn-ribbon protein possibly nucleic acid-binding - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00003609 55.0
HKD1_k127_1403771_86 Class III cytochrome C family - - - 0.00005827 55.0
HKD1_k127_1403771_9 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 531.0
HKD1_k127_1462591_0 Transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 412.0
HKD1_k127_1462591_1 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003518 300.0
HKD1_k127_1462591_11 RHS protein - - - 0.00000005045 64.0
HKD1_k127_1462591_12 Type VI secretion system (T6SS), amidase effector protein 4 - - - 0.0000001863 66.0
HKD1_k127_1462591_2 domain protein K01179,K12567,K20276,K21449 - 2.7.11.1,3.2.1.4 0.0000000000000000000000000000000000000000001089 180.0
HKD1_k127_1462591_3 self proteolysis K11021 - - 0.00000000000000000000000000000008731 142.0
HKD1_k127_1462591_4 COG3209 Rhs family protein - - - 0.0000000000000000000000000007551 133.0
HKD1_k127_1462591_5 COG3209 Rhs family protein - - - 0.00000000000000000000001221 119.0
HKD1_k127_1462591_6 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.000000000000000002009 88.0
HKD1_k127_1462591_7 TIGRFAM RHS repeat-associated core - - - 0.00000000000001545 88.0
HKD1_k127_1462591_8 Glycosyl hydrolases family 18 - - - 0.00000000000009076 85.0
HKD1_k127_1462591_9 TIGRFAM RHS repeat-associated core domain-containing protein, YD repeat protein - - - 0.0000000001314 67.0
HKD1_k127_148946_0 Radical SAM - - - 0.0 1004.0
HKD1_k127_148946_1 Highly conserved protein containing a thioredoxin domain K18581 - 3.2.1.180 1.519e-296 934.0
HKD1_k127_148946_10 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.29e-221 705.0
HKD1_k127_148946_11 PFAM glycoside hydrolase, family 29 K01206 - 3.2.1.51 2.53e-208 655.0
HKD1_k127_148946_12 Acyclic terpene utilisation family protein AtuA - - - 7.762e-208 654.0
HKD1_k127_148946_13 mandelate racemase muconate lactonizing K18334 - 4.2.1.68 4.732e-204 645.0
HKD1_k127_148946_14 Bacterial protein of unknown function (DUF885) - - - 5.62e-203 650.0
HKD1_k127_148946_15 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 608.0
HKD1_k127_148946_16 PfkB domain protein K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 578.0
HKD1_k127_148946_17 ABC transporter K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 576.0
HKD1_k127_148946_18 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 561.0
HKD1_k127_148946_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 529.0
HKD1_k127_148946_2 carboxylic acid catabolic process K01187 - 3.2.1.20 6.601e-267 837.0
HKD1_k127_148946_20 Alginate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 531.0
HKD1_k127_148946_21 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 524.0
HKD1_k127_148946_22 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 476.0
HKD1_k127_148946_23 PFAM Alcohol dehydrogenase GroES-like domain K00008,K00060 - 1.1.1.103,1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 477.0
HKD1_k127_148946_24 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 479.0
HKD1_k127_148946_25 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 483.0
HKD1_k127_148946_26 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 438.0
HKD1_k127_148946_27 Branched-chain amino acid transport system / permease component K10440,K10553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 429.0
HKD1_k127_148946_28 Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 429.0
HKD1_k127_148946_29 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 426.0
HKD1_k127_148946_3 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 6.912e-265 826.0
HKD1_k127_148946_30 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 420.0
HKD1_k127_148946_31 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 424.0
HKD1_k127_148946_32 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 396.0
HKD1_k127_148946_33 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007777 390.0
HKD1_k127_148946_34 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 388.0
HKD1_k127_148946_35 Aminoacyl tRNA synthetase class II, N-terminal domain K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 366.0
HKD1_k127_148946_36 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 366.0
HKD1_k127_148946_37 polygalacturonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 368.0
HKD1_k127_148946_38 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 332.0
HKD1_k127_148946_39 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 334.0
HKD1_k127_148946_4 Glycosyl-hydrolase 97 N-terminal K01187 - 3.2.1.20 3.137e-239 757.0
HKD1_k127_148946_40 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01707 - 4.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 321.0
HKD1_k127_148946_41 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 304.0
HKD1_k127_148946_42 SNARE associated Golgi protein K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 295.0
HKD1_k127_148946_43 competence protein COMEC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007709 299.0
HKD1_k127_148946_44 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 291.0
HKD1_k127_148946_45 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001688 278.0
HKD1_k127_148946_46 COG0477 Permeases of the major facilitator superfamily K03535,K08194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003717 286.0
HKD1_k127_148946_47 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001118 276.0
HKD1_k127_148946_48 amidohydrolase K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001185 278.0
HKD1_k127_148946_49 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000209 275.0
HKD1_k127_148946_5 protocatechuate 3,4-dioxygenase activity - - - 9.68e-234 767.0
HKD1_k127_148946_50 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000636 274.0
HKD1_k127_148946_51 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007836 284.0
HKD1_k127_148946_52 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004376 276.0
HKD1_k127_148946_53 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000504 281.0
HKD1_k127_148946_54 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001815 276.0
HKD1_k127_148946_55 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000116 264.0
HKD1_k127_148946_56 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003496 260.0
HKD1_k127_148946_57 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000006762 254.0
HKD1_k127_148946_58 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000312 244.0
HKD1_k127_148946_59 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000001101 227.0
HKD1_k127_148946_6 Psort location Cytoplasmic, score - - - 2.215e-231 734.0
HKD1_k127_148946_60 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000005743 214.0
HKD1_k127_148946_61 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000009956 212.0
HKD1_k127_148946_62 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000006742 208.0
HKD1_k127_148946_63 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000001463 203.0
HKD1_k127_148946_64 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000002131 196.0
HKD1_k127_148946_65 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000003085 194.0
HKD1_k127_148946_66 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000003647 196.0
HKD1_k127_148946_67 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000007133 204.0
HKD1_k127_148946_68 pfam nudix - - - 0.0000000000000000000000000000000000000000000000000007544 190.0
HKD1_k127_148946_69 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000001432 196.0
HKD1_k127_148946_7 Carboxyl transferase domain - - - 1.53e-230 726.0
HKD1_k127_148946_70 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.0000000000000000000000000000000000000000000006783 176.0
HKD1_k127_148946_71 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000001823 162.0
HKD1_k127_148946_72 - - - - 0.0000000000000000000000000000000000000000007006 159.0
HKD1_k127_148946_73 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000001708 149.0
HKD1_k127_148946_74 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000002922 154.0
HKD1_k127_148946_75 chlorophyll binding - - - 0.0000000000000000000000000000000000002321 153.0
HKD1_k127_148946_76 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000001951 149.0
HKD1_k127_148946_77 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000298 135.0
HKD1_k127_148946_78 6-phosphogluconolactonase activity - - - 0.000000000000000000000008974 115.0
HKD1_k127_148946_79 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000015 105.0
HKD1_k127_148946_8 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.344e-225 711.0
HKD1_k127_148946_80 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000001372 94.0
HKD1_k127_148946_81 Ribosomal protein L35 K02916 - - 0.0000000000000000001616 89.0
HKD1_k127_148946_82 PFAM SNARE associated Golgi protein - - - 0.000000000000000002625 94.0
HKD1_k127_148946_83 oxalate decarboxylase activity K11312 - - 0.00000000000000001398 90.0
HKD1_k127_148946_84 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000008983 78.0
HKD1_k127_148946_85 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000001079 84.0
HKD1_k127_148946_86 PFAM Fasciclin domain - - - 0.000000000000003115 83.0
HKD1_k127_148946_87 Alginate lyase - - - 0.00000000001082 68.0
HKD1_k127_148946_88 RDD family - - - 0.00000000004187 68.0
HKD1_k127_148946_89 - - - - 0.0000000005507 70.0
HKD1_k127_148946_9 TonB-dependent receptor - - - 3.102e-223 738.0
HKD1_k127_148946_90 Sigma-70 region 2 K03088 - - 0.000001045 50.0
HKD1_k127_148946_91 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000001661 55.0
HKD1_k127_148946_93 Rifampin ADP-ribosyl transferase - - - 0.00003241 48.0
HKD1_k127_1567212_0 Tricorn protease C1 domain K08676 - - 0.0 1212.0
HKD1_k127_1567212_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.627e-287 916.0
HKD1_k127_1567212_10 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 411.0
HKD1_k127_1567212_11 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 376.0
HKD1_k127_1567212_12 YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 372.0
HKD1_k127_1567212_13 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 349.0
HKD1_k127_1567212_14 von Willebrand factor (vWF) type A domain K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 328.0
HKD1_k127_1567212_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 306.0
HKD1_k127_1567212_16 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 296.0
HKD1_k127_1567212_17 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001173 303.0
HKD1_k127_1567212_18 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004021 282.0
HKD1_k127_1567212_19 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000001395 261.0
HKD1_k127_1567212_2 Radical SAM - - - 1.592e-213 682.0
HKD1_k127_1567212_20 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000005106 218.0
HKD1_k127_1567212_21 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000957 233.0
HKD1_k127_1567212_22 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000003414 206.0
HKD1_k127_1567212_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000001428 181.0
HKD1_k127_1567212_24 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000002623 166.0
HKD1_k127_1567212_25 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000002782 152.0
HKD1_k127_1567212_26 methyltransferase K18846 - 2.1.1.180 0.0000000000000000000000000000000003076 139.0
HKD1_k127_1567212_27 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000005653 137.0
HKD1_k127_1567212_28 - - - - 0.000000000000000000000000000000009749 144.0
HKD1_k127_1567212_29 outer membrane efflux protein - - - 0.00000000000000000000000000000004432 141.0
HKD1_k127_1567212_3 NADH oxidase - - - 3.247e-210 663.0
HKD1_k127_1567212_30 - - - - 0.0000000000000000000000000000003237 128.0
HKD1_k127_1567212_31 DinB superfamily - - - 0.0000000000000000000000006964 111.0
HKD1_k127_1567212_32 Parallel beta-helix repeats - - - 0.00000000000000000000004632 112.0
HKD1_k127_1567212_33 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000003301 98.0
HKD1_k127_1567212_34 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.00000000000000000004612 106.0
HKD1_k127_1567212_36 lytic transglycosylase activity K03194 - - 0.00000000001765 76.0
HKD1_k127_1567212_37 - - - - 0.000000001062 68.0
HKD1_k127_1567212_38 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000006364 66.0
HKD1_k127_1567212_39 PA14 - - - 0.0000000111 69.0
HKD1_k127_1567212_4 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 527.0
HKD1_k127_1567212_40 - - - - 0.0000003706 56.0
HKD1_k127_1567212_42 antibiotic catabolic process - - - 0.0000982 56.0
HKD1_k127_1567212_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 478.0
HKD1_k127_1567212_6 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 455.0
HKD1_k127_1567212_7 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 419.0
HKD1_k127_1567212_8 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 411.0
HKD1_k127_1567212_9 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 413.0
HKD1_k127_1580709_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1280.0
HKD1_k127_1580709_1 Alpha-2-Macroglobulin K06894 - - 1.97e-298 977.0
HKD1_k127_1580709_10 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 570.0
HKD1_k127_1580709_11 PFAM Glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 532.0
HKD1_k127_1580709_12 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 488.0
HKD1_k127_1580709_13 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 469.0
HKD1_k127_1580709_14 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 465.0
HKD1_k127_1580709_15 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 428.0
HKD1_k127_1580709_16 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 420.0
HKD1_k127_1580709_17 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 439.0
HKD1_k127_1580709_18 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 394.0
HKD1_k127_1580709_19 Glucose--fructose oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 377.0
HKD1_k127_1580709_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 2.823e-267 839.0
HKD1_k127_1580709_20 Transport permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 365.0
HKD1_k127_1580709_21 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 351.0
HKD1_k127_1580709_22 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 340.0
HKD1_k127_1580709_23 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 340.0
HKD1_k127_1580709_24 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 343.0
HKD1_k127_1580709_25 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 316.0
HKD1_k127_1580709_26 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 332.0
HKD1_k127_1580709_27 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 307.0
HKD1_k127_1580709_28 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003946 282.0
HKD1_k127_1580709_29 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000009648 255.0
HKD1_k127_1580709_3 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 3.486e-233 732.0
HKD1_k127_1580709_30 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000008912 254.0
HKD1_k127_1580709_31 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000004397 245.0
HKD1_k127_1580709_32 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000004629 239.0
HKD1_k127_1580709_33 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000001753 229.0
HKD1_k127_1580709_34 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000002282 231.0
HKD1_k127_1580709_35 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000003613 217.0
HKD1_k127_1580709_36 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000001995 213.0
HKD1_k127_1580709_37 - - - - 0.0000000000000000000000000000000000000000000000000000000002463 209.0
HKD1_k127_1580709_38 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000014 205.0
HKD1_k127_1580709_39 Stage II sporulation D domain protein K06381 - - 0.0000000000000000000000000000000000000000000000000000004565 220.0
HKD1_k127_1580709_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.978e-231 725.0
HKD1_k127_1580709_40 penicillin-binding protein - - - 0.00000000000000000000000000000000000000000000000000002065 209.0
HKD1_k127_1580709_41 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000004791 206.0
HKD1_k127_1580709_42 Protein of unknown function (DUF1175) K09934 - - 0.00000000000000000000000000000000000000000000000000005212 198.0
HKD1_k127_1580709_43 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000004606 188.0
HKD1_k127_1580709_44 - - - - 0.000000000000000000000000000000000000000000000002487 179.0
HKD1_k127_1580709_45 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000004806 172.0
HKD1_k127_1580709_46 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000008115 173.0
HKD1_k127_1580709_47 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000057 164.0
HKD1_k127_1580709_48 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000001716 164.0
HKD1_k127_1580709_49 Transposase IS200 like K07445 - - 0.0000000000000000000000000000000000000005926 154.0
HKD1_k127_1580709_5 Amidase K01426 - 3.5.1.4 2.463e-213 675.0
HKD1_k127_1580709_50 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.00000000000000000000000000000000000004387 145.0
HKD1_k127_1580709_51 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000007515 142.0
HKD1_k127_1580709_52 secondary active sulfate transmembrane transporter activity - - - 0.00000000000000000000000000000000001349 143.0
HKD1_k127_1580709_53 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000001437 145.0
HKD1_k127_1580709_54 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 0.0000000000000000000000000000000002159 148.0
HKD1_k127_1580709_55 GrpB protein - - - 0.000000000000000000000000000000002124 136.0
HKD1_k127_1580709_56 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000002653 143.0
HKD1_k127_1580709_57 Tetratricopeptide repeat - - - 0.0000000000000000000000000000003632 134.0
HKD1_k127_1580709_58 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000001728 127.0
HKD1_k127_1580709_59 acetyltransferase - - - 0.00000000000000000000000003634 112.0
HKD1_k127_1580709_6 Zinc carboxypeptidase - - - 4.385e-212 686.0
HKD1_k127_1580709_60 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000001013 108.0
HKD1_k127_1580709_61 Domain of unknown function (DUF4349) - - - 0.000000000000000000000007391 113.0
HKD1_k127_1580709_62 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000000000000000002641 103.0
HKD1_k127_1580709_63 isomerase activity K01821 - 5.3.2.6 0.000000000000000000000282 98.0
HKD1_k127_1580709_64 Protein of unknown function (DUF1211) - - - 0.0000000000000000000008007 102.0
HKD1_k127_1580709_65 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.000000000000000000001732 97.0
HKD1_k127_1580709_66 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000001842 100.0
HKD1_k127_1580709_67 oxidoreductase activity K07114,K12511 - - 0.000000000000000000005343 105.0
HKD1_k127_1580709_68 Domain of unknown function (DUF1844) - - - 0.000000000000005819 81.0
HKD1_k127_1580709_69 Cell division cycle 27 K03350 GO:0000003,GO:0000151,GO:0000152,GO:0000209,GO:0000278,GO:0000375,GO:0000377,GO:0000398,GO:0001775,GO:0003002,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005680,GO:0005737,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006139,GO:0006396,GO:0006397,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0007049,GO:0007088,GO:0007091,GO:0007275,GO:0007338,GO:0007343,GO:0007346,GO:0007389,GO:0008150,GO:0008152,GO:0008283,GO:0008356,GO:0008380,GO:0009056,GO:0009057,GO:0009566,GO:0009798,GO:0009948,GO:0009949,GO:0009952,GO:0009987,GO:0010467,GO:0010498,GO:0010564,GO:0010965,GO:0015630,GO:0016070,GO:0016071,GO:0016192,GO:0016567,GO:0016740,GO:0017156,GO:0019538,GO:0019787,GO:0019899,GO:0019902,GO:0019903,GO:0019941,GO:0019953,GO:0022402,GO:0022414,GO:0030163,GO:0031145,GO:0031461,GO:0031974,GO:0031981,GO:0032446,GO:0032501,GO:0032502,GO:0032940,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034641,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0043900,GO:0043901,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044784,GO:0045055,GO:0046483,GO:0046903,GO:0048519,GO:0048856,GO:0050789,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0051603,GO:0051704,GO:0051726,GO:0051783,GO:0051983,GO:0060467,GO:0060468,GO:0060471,GO:0061630,GO:0061659,GO:0065001,GO:0065007,GO:0070013,GO:0070647,GO:0070979,GO:0071704,GO:0080154,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1903047,GO:1905818,GO:1990234,GO:2000241,GO:2000242 - 0.0000000000000947 84.0
HKD1_k127_1580709_7 Serine hydrolase involved in the detoxification of formaldehyde K21105 - 3.1.1.102 5.581e-210 664.0
HKD1_k127_1580709_70 - - - - 0.00000000001418 70.0
HKD1_k127_1580709_71 glutamate-cysteine ligase activity - - - 0.0000000004379 64.0
HKD1_k127_1580709_72 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000001352 61.0
HKD1_k127_1580709_74 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000002482 55.0
HKD1_k127_1580709_75 periplasmic or secreted lipoprotein - - - 0.0000004516 59.0
HKD1_k127_1580709_76 Transglutaminase-like superfamily - - - 0.000000844 62.0
HKD1_k127_1580709_77 Protein of unknown function (DUF1211) - - - 0.000001973 53.0
HKD1_k127_1580709_78 - - - - 0.00000294 52.0
HKD1_k127_1580709_79 Carboxypeptidase regulatory-like domain - - - 0.00001395 55.0
HKD1_k127_1580709_8 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 611.0
HKD1_k127_1580709_80 Belongs to the UPF0337 (CsbD) family - - - 0.00002999 51.0
HKD1_k127_1580709_9 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 611.0
HKD1_k127_1585116_0 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 579.0
HKD1_k127_1585116_1 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 409.0
HKD1_k127_1585116_10 Belongs to the TPP enzyme family - - - 0.0000000000000000000000000000000000000231 165.0
HKD1_k127_1585116_11 domain protein K01637,K20276 - 4.1.3.1 0.000000000000000000000009985 118.0
HKD1_k127_1585116_12 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0000000000000001804 82.0
HKD1_k127_1585116_14 metallopeptidase activity K03933 - - 0.0000000085 65.0
HKD1_k127_1585116_2 Dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 360.0
HKD1_k127_1585116_3 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000003782 232.0
HKD1_k127_1585116_4 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000002801 223.0
HKD1_k127_1585116_5 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000001087 221.0
HKD1_k127_1585116_6 Lysophospholipase L1 and related esterases - GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0044238,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000005523 213.0
HKD1_k127_1585116_7 Protein of unknown function (DUF1269) - - - 0.0000000000000000000000000000000000000000000000000000000259 206.0
HKD1_k127_1585116_8 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000007073 168.0
HKD1_k127_1585116_9 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000003443 158.0
HKD1_k127_1598975_0 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 442.0
HKD1_k127_1598975_1 Tryptophan 2,3-dioxygenase K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 365.0
HKD1_k127_1598975_2 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000000001205 186.0
HKD1_k127_1598975_3 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000001052 180.0
HKD1_k127_1598975_4 UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.0000000004971 62.0
HKD1_k127_1598975_5 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.00000001408 56.0
HKD1_k127_179576_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 2713.0
HKD1_k127_179576_1 Tricorn protease homolog K08676 - - 0.0 1498.0
HKD1_k127_179576_10 Molybdopterin oxidoreductase Fe4S4 domain - - - 2.763e-227 711.0
HKD1_k127_179576_100 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000005555 156.0
HKD1_k127_179576_101 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000003885 154.0
HKD1_k127_179576_102 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000005949 143.0
HKD1_k127_179576_103 PHP domain protein - - - 0.000000000000000000000000000000000006137 153.0
HKD1_k127_179576_104 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000008997 151.0
HKD1_k127_179576_105 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000018 137.0
HKD1_k127_179576_106 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000475 132.0
HKD1_k127_179576_107 - - - - 0.00000000000000000000000000000001445 141.0
HKD1_k127_179576_108 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000003314 126.0
HKD1_k127_179576_109 Thioesterase superfamily K10806 - - 0.000000000000000000000000000001149 126.0
HKD1_k127_179576_11 Polysulphide reductase, NrfD K00185 - - 1.172e-217 683.0
HKD1_k127_179576_110 - - - - 0.000000000000000000000000000001307 123.0
HKD1_k127_179576_111 DinB family - - - 0.000000000000000000000000000004026 126.0
HKD1_k127_179576_112 PFAM von Willebrand factor type A K07114,K12511 - - 0.000000000000000000000000000006423 131.0
HKD1_k127_179576_113 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000006391 119.0
HKD1_k127_179576_114 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000003786 125.0
HKD1_k127_179576_115 PFAM TM2 domain - - - 0.00000000000000000000000001745 114.0
HKD1_k127_179576_116 Protein of unknown function (DUF2752) - - - 0.0000000000000000000000000498 112.0
HKD1_k127_179576_117 Thioredoxin-like - - - 0.000000000000000000000000214 119.0
HKD1_k127_179576_118 PFAM Forkhead-associated protein - - - 0.0000000000000000000000003236 113.0
HKD1_k127_179576_119 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.000000000000000000000001013 115.0
HKD1_k127_179576_12 Peptidase family M28 - - - 1.419e-200 640.0
HKD1_k127_179576_120 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000001325 115.0
HKD1_k127_179576_121 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000664 102.0
HKD1_k127_179576_122 - - - - 0.0000000000000000000004761 106.0
HKD1_k127_179576_123 YCII-related domain - - - 0.000000000000000000002322 102.0
HKD1_k127_179576_124 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000006827 95.0
HKD1_k127_179576_125 C4-type zinc ribbon domain K07164 - - 0.0000000000000000009491 95.0
HKD1_k127_179576_127 radical SAM domain protein - - - 0.000000000000009555 78.0
HKD1_k127_179576_128 Helix-hairpin-helix motif - - - 0.0000000000001243 75.0
HKD1_k127_179576_129 Stress responsive A/B Barrel Domain - - - 0.0000000000001556 74.0
HKD1_k127_179576_13 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 581.0
HKD1_k127_179576_130 PD-(D/E)XK nuclease superfamily - - - 0.000000000005178 67.0
HKD1_k127_179576_131 Interferon-induced transmembrane protein - - - 0.00000000001104 68.0
HKD1_k127_179576_132 YCII-related domain - - - 0.00000000009572 71.0
HKD1_k127_179576_133 Yip1 domain - - - 0.000000001141 70.0
HKD1_k127_179576_134 PFAM RDD domain containing protein - - - 0.00000000178 66.0
HKD1_k127_179576_135 Membrane-flanked domain-containing protein - - - 0.000000004359 65.0
HKD1_k127_179576_136 Forkhead associated domain - - - 0.00000000741 68.0
HKD1_k127_179576_137 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000105 68.0
HKD1_k127_179576_138 - - - - 0.00000001153 59.0
HKD1_k127_179576_139 Peptidase family S41 - - - 0.00000004173 66.0
HKD1_k127_179576_14 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 570.0
HKD1_k127_179576_140 YceI-like domain - - - 0.0000001398 61.0
HKD1_k127_179576_141 - - - - 0.0000004888 58.0
HKD1_k127_179576_142 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000008465 58.0
HKD1_k127_179576_143 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000003948 60.0
HKD1_k127_179576_144 FecR protein - - - 0.00001496 57.0
HKD1_k127_179576_145 Putative peptidoglycan binding domain - - - 0.00002207 51.0
HKD1_k127_179576_146 YtkA-like - - - 0.00006586 51.0
HKD1_k127_179576_147 - - - - 0.00007794 54.0
HKD1_k127_179576_148 chlorophyll binding - - - 0.00009613 54.0
HKD1_k127_179576_149 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0001156 51.0
HKD1_k127_179576_15 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 543.0
HKD1_k127_179576_150 PFAM PepSY-associated TM helix domain protein - - - 0.0002588 50.0
HKD1_k127_179576_16 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 530.0
HKD1_k127_179576_17 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 514.0
HKD1_k127_179576_18 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 511.0
HKD1_k127_179576_19 amino acid transport K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 494.0
HKD1_k127_179576_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1155.0
HKD1_k127_179576_20 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 488.0
HKD1_k127_179576_21 Peptidase, S9A B C family, catalytic domain protein K01303 - 3.4.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 496.0
HKD1_k127_179576_22 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 481.0
HKD1_k127_179576_23 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 468.0
HKD1_k127_179576_24 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 477.0
HKD1_k127_179576_25 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 456.0
HKD1_k127_179576_26 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 447.0
HKD1_k127_179576_27 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 438.0
HKD1_k127_179576_28 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 444.0
HKD1_k127_179576_29 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 431.0
HKD1_k127_179576_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1079.0
HKD1_k127_179576_30 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 427.0
HKD1_k127_179576_31 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 396.0
HKD1_k127_179576_32 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 420.0
HKD1_k127_179576_33 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 394.0
HKD1_k127_179576_34 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008097 415.0
HKD1_k127_179576_35 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 383.0
HKD1_k127_179576_36 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 385.0
HKD1_k127_179576_37 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 391.0
HKD1_k127_179576_38 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 372.0
HKD1_k127_179576_39 Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 365.0
HKD1_k127_179576_4 4Fe-4S dicluster domain K00184 - - 0.0 1069.0
HKD1_k127_179576_40 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 361.0
HKD1_k127_179576_41 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 357.0
HKD1_k127_179576_42 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 357.0
HKD1_k127_179576_43 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 352.0
HKD1_k127_179576_44 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 343.0
HKD1_k127_179576_45 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 361.0
HKD1_k127_179576_46 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 343.0
HKD1_k127_179576_47 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 331.0
HKD1_k127_179576_48 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 320.0
HKD1_k127_179576_49 copper resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 329.0
HKD1_k127_179576_5 helicase activity - - - 0.0 1065.0
HKD1_k127_179576_50 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 310.0
HKD1_k127_179576_51 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 330.0
HKD1_k127_179576_52 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 317.0
HKD1_k127_179576_53 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 302.0
HKD1_k127_179576_54 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 294.0
HKD1_k127_179576_55 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 294.0
HKD1_k127_179576_56 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 291.0
HKD1_k127_179576_57 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002524 291.0
HKD1_k127_179576_58 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000365 283.0
HKD1_k127_179576_59 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002065 280.0
HKD1_k127_179576_6 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 1.644e-306 954.0
HKD1_k127_179576_60 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001339 283.0
HKD1_k127_179576_61 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001786 288.0
HKD1_k127_179576_62 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002337 291.0
HKD1_k127_179576_63 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006769 273.0
HKD1_k127_179576_64 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004135 269.0
HKD1_k127_179576_65 DEAD DEAH box helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007842 265.0
HKD1_k127_179576_66 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005666 256.0
HKD1_k127_179576_67 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001171 260.0
HKD1_k127_179576_68 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000146 253.0
HKD1_k127_179576_69 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001167 253.0
HKD1_k127_179576_7 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 8.604e-271 842.0
HKD1_k127_179576_70 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006257 241.0
HKD1_k127_179576_71 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000003949 252.0
HKD1_k127_179576_72 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000008694 243.0
HKD1_k127_179576_73 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004933 235.0
HKD1_k127_179576_74 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002462 235.0
HKD1_k127_179576_75 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.0000000000000000000000000000000000000000000000000000000000000001747 236.0
HKD1_k127_179576_76 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000000000000000000000000000000000000002208 226.0
HKD1_k127_179576_77 DSHCT - - - 0.0000000000000000000000000000000000000000000000000000000000000003147 243.0
HKD1_k127_179576_78 PQQ-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000008673 231.0
HKD1_k127_179576_79 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000006692 212.0
HKD1_k127_179576_8 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.293e-255 806.0
HKD1_k127_179576_80 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000002727 220.0
HKD1_k127_179576_81 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000159 207.0
HKD1_k127_179576_82 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000004822 208.0
HKD1_k127_179576_83 methyltransferase K05928 - 2.1.1.95 0.000000000000000000000000000000000000000000000000000000009665 207.0
HKD1_k127_179576_84 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000005406 202.0
HKD1_k127_179576_85 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000002401 213.0
HKD1_k127_179576_86 - - - - 0.000000000000000000000000000000000000000000000000000001038 200.0
HKD1_k127_179576_87 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000001343 187.0
HKD1_k127_179576_88 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000008141 184.0
HKD1_k127_179576_89 Uncharacterized ACR, COG1993 K06199,K09137 - - 0.00000000000000000000000000000000000000000000008529 172.0
HKD1_k127_179576_9 Penicillin amidase K07116 - 3.5.1.97 1.837e-229 733.0
HKD1_k127_179576_90 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000000000000002181 167.0
HKD1_k127_179576_91 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000007115 166.0
HKD1_k127_179576_92 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000002556 174.0
HKD1_k127_179576_93 diguanylate cyclase - - - 0.000000000000000000000000000000000000000002383 174.0
HKD1_k127_179576_94 - - - - 0.00000000000000000000000000000000000000000501 160.0
HKD1_k127_179576_95 Cation transport regulator - - - 0.000000000000000000000000000000000000000008752 160.0
HKD1_k127_179576_96 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000009613 164.0
HKD1_k127_179576_97 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000002948 157.0
HKD1_k127_179576_98 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000001636 161.0
HKD1_k127_179576_99 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000001653 159.0
HKD1_k127_1826948_0 Pyridine nucleotide-disulphide oxidoreductase - - - 1.009e-254 790.0
HKD1_k127_1826948_1 Aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 527.0
HKD1_k127_1826948_10 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007323 242.0
HKD1_k127_1826948_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001181 248.0
HKD1_k127_1826948_12 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000003464 195.0
HKD1_k127_1826948_13 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000006972 165.0
HKD1_k127_1826948_14 PFAM Abortive infection protein K07052 - - 0.00000000000000000000000000000000000000002648 161.0
HKD1_k127_1826948_15 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000003253 149.0
HKD1_k127_1826948_16 MerR, DNA binding K13639 - - 0.00000000000000000000001374 107.0
HKD1_k127_1826948_17 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000004399 89.0
HKD1_k127_1826948_18 Transcription elongation factor, GreA/GreB, C-term - - - 0.00000000000000001312 88.0
HKD1_k127_1826948_19 - - - - 0.0000005713 53.0
HKD1_k127_1826948_2 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 482.0
HKD1_k127_1826948_20 Cupin 2, conserved barrel domain protein - - - 0.000002669 56.0
HKD1_k127_1826948_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 461.0
HKD1_k127_1826948_4 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 370.0
HKD1_k127_1826948_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 366.0
HKD1_k127_1826948_6 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 379.0
HKD1_k127_1826948_7 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 353.0
HKD1_k127_1826948_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000101 262.0
HKD1_k127_1826948_9 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006989 237.0
HKD1_k127_1834299_0 COG NOG06097 non supervised orthologous group - - - 2.496e-282 899.0
HKD1_k127_1834299_1 Glycosyl hydrolases family 31 - - - 9.739e-217 694.0
HKD1_k127_1834299_2 Pectate lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 568.0
HKD1_k127_1834299_3 GDSL-like Lipase/Acylhydrolase K01051 - 3.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 373.0
HKD1_k127_1834299_4 beta-galactosidase activity - - - 0.000000006388 61.0
HKD1_k127_1883693_0 Sulfatase K01130 - 3.1.6.1 0.0 1143.0
HKD1_k127_1883693_1 radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 526.0
HKD1_k127_1883693_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 482.0
HKD1_k127_1883693_3 Protein of unknown function (DUF3604) - - - 0.000000000000002391 78.0
HKD1_k127_191468_0 glycyl-radical enzyme activating activity K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 602.0
HKD1_k127_191468_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 616.0
HKD1_k127_191468_10 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000000001985 155.0
HKD1_k127_191468_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000004839 113.0
HKD1_k127_191468_13 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000003005 102.0
HKD1_k127_191468_14 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000007387 94.0
HKD1_k127_191468_15 - - - - 0.0000000000000000008332 96.0
HKD1_k127_191468_17 Dienelactone hydrolase family - - - 0.00000006974 65.0
HKD1_k127_191468_18 Serine aminopeptidase, S33 K06889 - - 0.000003036 59.0
HKD1_k127_191468_19 AntiSigma factor - - - 0.00001987 55.0
HKD1_k127_191468_2 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 451.0
HKD1_k127_191468_3 PFAM CBS domain containing protein K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 353.0
HKD1_k127_191468_4 Belongs to the mandelate racemase muconate lactonizing enzyme family K19802 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 353.0
HKD1_k127_191468_5 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000002428 265.0
HKD1_k127_191468_6 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005001 254.0
HKD1_k127_191468_7 3-hydroxyanthranilate 3,4-dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000003528 198.0
HKD1_k127_191468_8 FMN reductase (NADPH) activity K00299,K16902 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006790,GO:0006805,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008752,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009111,GO:0009267,GO:0009308,GO:0009310,GO:0009410,GO:0009605,GO:0009970,GO:0009987,GO:0009991,GO:0010181,GO:0016043,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019439,GO:0019694,GO:0019752,GO:0022607,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032787,GO:0033554,GO:0034641,GO:0036094,GO:0042178,GO:0042221,GO:0042365,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0042594,GO:0043167,GO:0043168,GO:0043420,GO:0043421,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046306,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0052873,GO:0055114,GO:0065003,GO:0070887,GO:0071466,GO:0071496,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.1.38,1.5.1.45 0.00000000000000000000000000000000000000000000000000002423 192.0
HKD1_k127_191468_9 - - - - 0.00000000000000000000000000000000000000000000000000003902 198.0
HKD1_k127_2012492_0 Penicillin amidase K01434 - 3.5.1.11 0.0 1040.0
HKD1_k127_2012492_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 4.225e-296 926.0
HKD1_k127_2012492_10 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 501.0
HKD1_k127_2012492_11 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 492.0
HKD1_k127_2012492_12 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 469.0
HKD1_k127_2012492_13 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 449.0
HKD1_k127_2012492_14 Thrombospondin type 3 repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 465.0
HKD1_k127_2012492_15 4Fe-4S dicluster domain K17723 - 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 439.0
HKD1_k127_2012492_16 phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 442.0
HKD1_k127_2012492_17 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 461.0
HKD1_k127_2012492_18 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 413.0
HKD1_k127_2012492_19 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 415.0
HKD1_k127_2012492_2 Amidohydrolase family K01464 - 3.5.2.2 1.187e-195 620.0
HKD1_k127_2012492_20 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 407.0
HKD1_k127_2012492_21 PFAM beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 416.0
HKD1_k127_2012492_22 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 410.0
HKD1_k127_2012492_23 TIGRFAM Outer membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 429.0
HKD1_k127_2012492_24 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 356.0
HKD1_k127_2012492_25 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 346.0
HKD1_k127_2012492_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 334.0
HKD1_k127_2012492_27 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 318.0
HKD1_k127_2012492_28 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 299.0
HKD1_k127_2012492_29 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 302.0
HKD1_k127_2012492_3 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 562.0
HKD1_k127_2012492_30 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 301.0
HKD1_k127_2012492_31 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003794 280.0
HKD1_k127_2012492_32 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004394 248.0
HKD1_k127_2012492_33 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000001254 236.0
HKD1_k127_2012492_34 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000008717 231.0
HKD1_k127_2012492_35 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000003377 210.0
HKD1_k127_2012492_36 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000003258 205.0
HKD1_k127_2012492_37 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000001807 197.0
HKD1_k127_2012492_38 endonuclease I - - - 0.0000000000000000000000000000000000000000000000000000003701 220.0
HKD1_k127_2012492_39 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000000000000000000005967 194.0
HKD1_k127_2012492_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 558.0
HKD1_k127_2012492_40 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000002961 196.0
HKD1_k127_2012492_41 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.00000000000000000000000000000000000000000000000000002804 198.0
HKD1_k127_2012492_42 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000000000000000003492 190.0
HKD1_k127_2012492_43 - - - - 0.000000000000000000000000000000000000000000000000000106 194.0
HKD1_k127_2012492_44 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000001814 178.0
HKD1_k127_2012492_45 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000002014 179.0
HKD1_k127_2012492_46 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000128 189.0
HKD1_k127_2012492_47 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000003003 164.0
HKD1_k127_2012492_48 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000003634 157.0
HKD1_k127_2012492_49 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000000000006082 149.0
HKD1_k127_2012492_5 Serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 546.0
HKD1_k127_2012492_50 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000003524 147.0
HKD1_k127_2012492_51 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000278 128.0
HKD1_k127_2012492_52 YCII-related domain - - - 0.000000000000000000000000000001237 126.0
HKD1_k127_2012492_53 Domain of unknown function (DU1801) - - - 0.000000000000000000000000115 112.0
HKD1_k127_2012492_54 Protein of unknown function (DUF2834) - - - 0.0000000000000000000000007858 108.0
HKD1_k127_2012492_55 Iron permease FTR1 K07243 - - 0.00000000000000000000002016 110.0
HKD1_k127_2012492_57 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000009067 98.0
HKD1_k127_2012492_6 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 544.0
HKD1_k127_2012492_60 polymorphic outer membrane protein - - - 0.000000000000005502 91.0
HKD1_k127_2012492_61 Transposase and inactivated derivatives - - - 0.0000000000001841 72.0
HKD1_k127_2012492_62 Protein of unknown function (DUF3108) - - - 0.0000000000007049 81.0
HKD1_k127_2012492_64 6-phosphogluconolactonase activity - - - 0.0000000002502 75.0
HKD1_k127_2012492_65 Redoxin - - - 0.00000000188 63.0
HKD1_k127_2012492_66 - - - - 0.000000008607 63.0
HKD1_k127_2012492_67 Protein of unknown function (DUF3108) - - - 0.0000000215 67.0
HKD1_k127_2012492_68 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.00008754 53.0
HKD1_k127_2012492_69 Transposase and inactivated derivatives - - - 0.0001958 47.0
HKD1_k127_2012492_7 Protein of unknown function (DUF692) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 524.0
HKD1_k127_2012492_70 Cupin 2, conserved barrel domain protein - - - 0.0006981 51.0
HKD1_k127_2012492_8 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 509.0
HKD1_k127_2012492_9 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 507.0
HKD1_k127_2037976_0 serine-type exopeptidase activity K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 4.146e-293 920.0
HKD1_k127_2037976_1 Belongs to the peptidase M16 family K07263 - - 1.085e-263 841.0
HKD1_k127_2037976_10 including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 320.0
HKD1_k127_2037976_11 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 317.0
HKD1_k127_2037976_12 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 314.0
HKD1_k127_2037976_13 Protease prsW family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 293.0
HKD1_k127_2037976_14 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006273 289.0
HKD1_k127_2037976_15 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008723 279.0
HKD1_k127_2037976_16 Oxidoreductase activity. It is involved in the biological process described with metabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004091 274.0
HKD1_k127_2037976_17 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001345 275.0
HKD1_k127_2037976_18 Domain of unknown function (DUF1611_C) P-loop domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001916 244.0
HKD1_k127_2037976_19 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001952 241.0
HKD1_k127_2037976_2 PFAM WD domain, G-beta repeat - - - 6.704e-209 689.0
HKD1_k127_2037976_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07291 - 2.7.8.34 0.0000000000000000000000000000000000000000000000000000000371 205.0
HKD1_k127_2037976_21 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000009785 204.0
HKD1_k127_2037976_22 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000001741 214.0
HKD1_k127_2037976_23 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000002339 202.0
HKD1_k127_2037976_24 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000006768 208.0
HKD1_k127_2037976_25 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000005598 199.0
HKD1_k127_2037976_26 PFAM Protein kinase domain - - - 0.000000000000000000000000000000000000000000000008248 191.0
HKD1_k127_2037976_27 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K06878 - - 0.0000000000000000000000000000000000000000000002513 172.0
HKD1_k127_2037976_28 Disulphide bond corrector protein DsbC - - - 0.0000000000000000000000000000000000001355 147.0
HKD1_k127_2037976_29 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000004018 143.0
HKD1_k127_2037976_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 572.0
HKD1_k127_2037976_30 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000000000001521 153.0
HKD1_k127_2037976_31 HD domain - - - 0.000000000000000000000000000000003599 140.0
HKD1_k127_2037976_32 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000001041 119.0
HKD1_k127_2037976_33 von Willebrand factor, type A K07114 - - 0.000000000000000000000000002788 124.0
HKD1_k127_2037976_34 - - - - 0.00000000000000000000000005867 109.0
HKD1_k127_2037976_35 protein containing caspase domain - - - 0.000000000000000000000003301 120.0
HKD1_k127_2037976_36 TIR domain - - - 0.000000000000000000000005472 114.0
HKD1_k127_2037976_37 Protein of unknown function (DUF971) - - - 0.000000000000000000000183 100.0
HKD1_k127_2037976_38 Probable zinc-ribbon domain - - - 0.000000000000000000001235 99.0
HKD1_k127_2037976_39 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000002759 95.0
HKD1_k127_2037976_4 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 508.0
HKD1_k127_2037976_40 Polysaccharide export protein K01991,K20988 - - 0.00000000000000001297 94.0
HKD1_k127_2037976_41 COG0457 FOG TPR repeat - - - 0.0000000000000000181 98.0
HKD1_k127_2037976_42 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000001941 78.0
HKD1_k127_2037976_43 Domain of unknown function (DUF4384) - - - 0.0000000000004587 79.0
HKD1_k127_2037976_44 TIGRFAM bacillithiol system protein YtxJ - - - 0.00000000002089 68.0
HKD1_k127_2037976_45 PFAM heat shock protein DnaJ domain protein K05516 - - 0.00000000006458 75.0
HKD1_k127_2037976_46 6-phosphogluconolactonase activity K07404 - 3.1.1.31 0.000000000966 72.0
HKD1_k127_2037976_47 PFAM Orthopoxvirus protein of - - - 0.0000001222 63.0
HKD1_k127_2037976_48 D12 class N6 adenine-specific DNA methyltransferase K07318 - 2.1.1.72 0.0000001353 63.0
HKD1_k127_2037976_49 Terminase RNaseH-like domain - - - 0.00002939 48.0
HKD1_k127_2037976_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 496.0
HKD1_k127_2037976_50 AAA ATPase domain K01768 - 4.6.1.1 0.00005253 56.0
HKD1_k127_2037976_51 negative regulation of ER-associated ubiquitin-dependent protein catabolic process K16365 GO:0003674,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006457,GO:0006508,GO:0006511,GO:0006605,GO:0006612,GO:0006620,GO:0006807,GO:0006810,GO:0006886,GO:0006950,GO:0006996,GO:0007029,GO:0008022,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009896,GO:0009987,GO:0010033,GO:0010243,GO:0010256,GO:0010498,GO:0010604,GO:0010605,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016192,GO:0019222,GO:0019538,GO:0019941,GO:0030162,GO:0030163,GO:0030433,GO:0030544,GO:0031072,GO:0031323,GO:0031324,GO:0031325,GO:0031329,GO:0031330,GO:0031331,GO:0031333,GO:0032268,GO:0032269,GO:0032270,GO:0032434,GO:0032435,GO:0032436,GO:0032459,GO:0032460,GO:0032947,GO:0032991,GO:0033036,GO:0033365,GO:0033554,GO:0034613,GO:0034976,GO:0036503,GO:0042176,GO:0042177,GO:0042221,GO:0042802,GO:0042803,GO:0042886,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0043621,GO:0043632,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044877,GO:0045047,GO:0045048,GO:0045184,GO:0045732,GO:0045861,GO:0045862,GO:0046907,GO:0046982,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051087,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051205,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051603,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0061024,GO:0061136,GO:0065007,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0071816,GO:0071840,GO:0072379,GO:0072380,GO:0072594,GO:0072599,GO:0072657,GO:0080090,GO:0080134,GO:0080135,GO:0090150,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901799,GO:1901800,GO:1903050,GO:1903051,GO:1903052,GO:1903069,GO:1903070,GO:1903071,GO:1903332,GO:1903334,GO:1903362,GO:1903363,GO:1903364,GO:1903573,GO:1903644,GO:1903646,GO:1904288,GO:1904292,GO:1904293,GO:1904294,GO:1905897,GO:1905898,GO:2000058,GO:2000059,GO:2000060 - 0.00008007 55.0
HKD1_k127_2037976_52 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0007563 48.0
HKD1_k127_2037976_6 Belongs to the glycosyl hydrolase family 6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 505.0
HKD1_k127_2037976_7 Phytanoyl-CoA dioxygenase (PhyH) K00477 - 1.14.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 376.0
HKD1_k127_2037976_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 374.0
HKD1_k127_2037976_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 351.0
HKD1_k127_2063873_0 COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 532.0
HKD1_k127_2063873_1 aminotransferase class I and II K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 355.0
HKD1_k127_2063873_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003177 283.0
HKD1_k127_2063873_3 Domain of unknown function (DUF5069) - - - 0.0000000000000000000000000000000000000000000000000001304 189.0
HKD1_k127_2063873_4 - - - - 0.00000000000000000000000000006043 119.0
HKD1_k127_2063873_5 - - - - 0.0000001217 55.0
HKD1_k127_20866_0 Peptidase family M3 K01284 - 3.4.15.5 0.0 1045.0
HKD1_k127_20866_1 Flavin containing amine oxidoreductase - - - 8.205e-293 904.0
HKD1_k127_20866_10 response regulator K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 332.0
HKD1_k127_20866_11 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002471 278.0
HKD1_k127_20866_12 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002727 278.0
HKD1_k127_20866_13 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001428 254.0
HKD1_k127_20866_14 KWG Leptospira - - - 0.000000000000000000000000000000000000000000000000000000000000000000001663 249.0
HKD1_k127_20866_15 DNA ligase D, 3'-phosphoesterase domain K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000004187 213.0
HKD1_k127_20866_16 DinB family - - - 0.00000000000000000000000000000000000000000000000000000005561 200.0
HKD1_k127_20866_17 - - - - 0.000000000000000000000000000000000000000000001769 172.0
HKD1_k127_20866_18 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000001524 153.0
HKD1_k127_20866_19 C-3'',4'' desaturase CrtD - - - 0.00000000000000000000000000000000000148 154.0
HKD1_k127_20866_2 PFAM Amino acid permease K03294 - - 8.227e-225 710.0
HKD1_k127_20866_20 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000007946 104.0
HKD1_k127_20866_21 Putative regulatory protein - - - 0.000000000000000002092 90.0
HKD1_k127_20866_22 metal-dependent membrane protease K07052 - - 0.0000000002894 71.0
HKD1_k127_20866_24 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000002744 63.0
HKD1_k127_20866_25 - - - - 0.000001771 49.0
HKD1_k127_20866_26 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000002022 59.0
HKD1_k127_20866_27 - - - - 0.00009659 51.0
HKD1_k127_20866_28 - - - - 0.0001967 53.0
HKD1_k127_20866_29 von Willebrand factor (vWF) type A domain - - - 0.0002712 53.0
HKD1_k127_20866_3 Amidohydrolase family - - - 3.111e-197 635.0
HKD1_k127_20866_30 COG0607 Rhodanese-related sulfurtransferase - - - 0.0003393 47.0
HKD1_k127_20866_4 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 534.0
HKD1_k127_20866_5 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 522.0
HKD1_k127_20866_6 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 406.0
HKD1_k127_20866_7 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 370.0
HKD1_k127_20866_8 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 361.0
HKD1_k127_20866_9 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 364.0
HKD1_k127_2129840_0 in Yersinia the HmsR protein is an inner membrane protein K11936 - - 0.0 1176.0
HKD1_k127_2129840_1 PFAM Type II secretion system protein E K02652 - - 1.589e-217 691.0
HKD1_k127_2129840_10 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 426.0
HKD1_k127_2129840_11 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 297.0
HKD1_k127_2129840_12 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 291.0
HKD1_k127_2129840_13 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002168 283.0
HKD1_k127_2129840_14 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006778 274.0
HKD1_k127_2129840_15 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000002545 263.0
HKD1_k127_2129840_16 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002416 252.0
HKD1_k127_2129840_17 protein conserved in bacteria K09974 - - 0.00000000000000000000000000000000000000000000000000000000000003862 222.0
HKD1_k127_2129840_18 Sortase and related acyltransferases K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000004991 214.0
HKD1_k127_2129840_19 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000002391 198.0
HKD1_k127_2129840_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 9.719e-217 692.0
HKD1_k127_2129840_20 Belongs to the GSP D family K02453 - - 0.000000000000000000000000000000000000000008835 178.0
HKD1_k127_2129840_21 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000001248 160.0
HKD1_k127_2129840_22 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000132 157.0
HKD1_k127_2129840_23 Participates in transcription elongation, termination and antitermination - - - 0.00000000000000000000000000000000000001103 161.0
HKD1_k127_2129840_24 SnoaL-like domain - - - 0.0000000000000000000000000000000000007452 143.0
HKD1_k127_2129840_25 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000001081 143.0
HKD1_k127_2129840_26 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000004016 129.0
HKD1_k127_2129840_27 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000004017 124.0
HKD1_k127_2129840_28 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000001047 122.0
HKD1_k127_2129840_29 Sigma-70, region 4 K03088 - - 0.000000000000000000000000001836 120.0
HKD1_k127_2129840_3 Amino acid permease K03294 - - 1.657e-212 670.0
HKD1_k127_2129840_30 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000002285 119.0
HKD1_k127_2129840_31 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000007394 106.0
HKD1_k127_2129840_32 IMP dehydrogenase activity K03281 - - 0.0000000000000000003478 89.0
HKD1_k127_2129840_33 - - - - 0.000000000000000001577 94.0
HKD1_k127_2129840_34 Cupin domain - - - 0.0000000000000003013 85.0
HKD1_k127_2129840_35 - - - - 0.00000000006352 68.0
HKD1_k127_2129840_36 Domain of unknown function (DUF4440) - - - 0.000000001245 67.0
HKD1_k127_2129840_4 Carboxypeptidase regulatory-like domain - - - 1.575e-201 665.0
HKD1_k127_2129840_5 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 518.0
HKD1_k127_2129840_6 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 509.0
HKD1_k127_2129840_7 DNA polymerase K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 489.0
HKD1_k127_2129840_8 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 463.0
HKD1_k127_2129840_9 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 460.0
HKD1_k127_2155290_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 7.97e-242 761.0
HKD1_k127_2155290_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 311.0
HKD1_k127_2155290_10 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000006946 110.0
HKD1_k127_2155290_12 - - - - 0.00000000000000006487 91.0
HKD1_k127_2155290_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000004227 92.0
HKD1_k127_2155290_14 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.00000000000001554 79.0
HKD1_k127_2155290_15 - - - - 0.00000000000001974 83.0
HKD1_k127_2155290_17 outer membrane autotransporter barrel domain protein - - - 0.00000008364 62.0
HKD1_k127_2155290_2 Beta-lactamase K01467 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000001515 261.0
HKD1_k127_2155290_3 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005231 244.0
HKD1_k127_2155290_4 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000001179 216.0
HKD1_k127_2155290_5 Putative cyclase K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000000000000000000001464 204.0
HKD1_k127_2155290_7 - - - - 0.0000000000000000000000000000000000000003151 154.0
HKD1_k127_2155290_8 - - - - 0.000000000000000000000000000000000000302 145.0
HKD1_k127_2155290_9 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000007992 119.0
HKD1_k127_2173340_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1275.0
HKD1_k127_2173340_1 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0 1098.0
HKD1_k127_2173340_10 gluconolactonase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 458.0
HKD1_k127_2173340_11 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 449.0
HKD1_k127_2173340_12 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 411.0
HKD1_k127_2173340_13 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 331.0
HKD1_k127_2173340_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 313.0
HKD1_k127_2173340_15 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004141 290.0
HKD1_k127_2173340_16 Trypsin-like serine protease K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000002095 268.0
HKD1_k127_2173340_17 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001763 259.0
HKD1_k127_2173340_18 Glucokinase K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000003952 241.0
HKD1_k127_2173340_19 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000005403 243.0
HKD1_k127_2173340_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.81e-312 970.0
HKD1_k127_2173340_21 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000001389 166.0
HKD1_k127_2173340_22 - - - - 0.0000000000000000000000000000000000001369 142.0
HKD1_k127_2173340_23 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000001022 123.0
HKD1_k127_2173340_24 - - - - 0.000000000000000000000000000005988 125.0
HKD1_k127_2173340_25 oxidoreductase activity - - - 0.0000000000000000000000001525 124.0
HKD1_k127_2173340_29 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000001109 73.0
HKD1_k127_2173340_3 Fibronectin type III-like domain K05349 - 3.2.1.21 7.306e-301 940.0
HKD1_k127_2173340_30 TPR repeat - - - 0.00000000000146 76.0
HKD1_k127_2173340_33 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0005016 42.0
HKD1_k127_2173340_4 Belongs to the glycosyl hydrolase 3 family K05349 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0008422,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015926,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.21 2.627e-256 814.0
HKD1_k127_2173340_5 Putative carbohydrate binding domain K12373 - 3.2.1.52 4.026e-245 779.0
HKD1_k127_2173340_6 ASPIC and UnbV - - - 2.613e-223 704.0
HKD1_k127_2173340_7 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 6.668e-199 643.0
HKD1_k127_2173340_8 beta-galactosidase activity K05970 - 3.1.1.53 2.886e-197 636.0
HKD1_k127_2173340_9 Sigma-54 interaction domain K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 616.0
HKD1_k127_2178128_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 3.18e-320 992.0
HKD1_k127_2178128_1 amino acid peptide transporter K03305,K06218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 591.0
HKD1_k127_2178128_10 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00002278 48.0
HKD1_k127_2178128_2 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000002993 227.0
HKD1_k127_2178128_3 Protein of unknown function (DUF3616) - - - 0.0000000000000000000000000000000000000000000000000000001215 209.0
HKD1_k127_2178128_4 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000003221 179.0
HKD1_k127_2178128_5 - - - - 0.000000000000000000000000000000000000009149 152.0
HKD1_k127_2178128_6 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000001754 101.0
HKD1_k127_2178128_7 - - - - 0.000000000000000003362 89.0
HKD1_k127_2178128_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K04760 - - 0.0000000001738 67.0
HKD1_k127_2178128_9 PFAM RNP-1 like RNA-binding protein - - - 0.00000001484 57.0
HKD1_k127_2232751_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520 - 1.16.1.1 6.033e-215 677.0
HKD1_k127_2232751_1 Epoxide hydrolase N terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 608.0
HKD1_k127_2232751_10 cheY-homologous receiver domain - - - 0.0000000000000000000000000003399 119.0
HKD1_k127_2232751_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18990 - - 0.000000000000008344 86.0
HKD1_k127_2232751_12 PFAM Cupin 2, conserved barrel - - - 0.0002695 49.0
HKD1_k127_2232751_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 357.0
HKD1_k127_2232751_3 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 321.0
HKD1_k127_2232751_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000007298 239.0
HKD1_k127_2232751_5 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000000000004858 230.0
HKD1_k127_2232751_6 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000001441 171.0
HKD1_k127_2232751_7 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000000000000000000000000000000000001323 164.0
HKD1_k127_2232751_8 TIGRFAM type I secretion membrane fusion protein, HlyD family - - - 0.0000000000000000000000000000000001884 138.0
HKD1_k127_2232751_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000003624 133.0
HKD1_k127_2350726_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.47e-297 933.0
HKD1_k127_2350726_1 PFAM NHL repeat - - - 1.655e-198 639.0
HKD1_k127_2350726_10 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 453.0
HKD1_k127_2350726_11 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 407.0
HKD1_k127_2350726_12 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 349.0
HKD1_k127_2350726_13 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 349.0
HKD1_k127_2350726_14 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 336.0
HKD1_k127_2350726_15 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 318.0
HKD1_k127_2350726_16 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 339.0
HKD1_k127_2350726_17 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 305.0
HKD1_k127_2350726_18 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 301.0
HKD1_k127_2350726_19 Ferritin, Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 280.0
HKD1_k127_2350726_2 PFAM Pyridoxal-dependent decarboxylase conserved domain K01580,K01593,K13745 - 4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 584.0
HKD1_k127_2350726_20 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002471 278.0
HKD1_k127_2350726_21 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005334 258.0
HKD1_k127_2350726_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005331 255.0
HKD1_k127_2350726_23 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000001422 238.0
HKD1_k127_2350726_24 Inositol monophosphatase family K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000003552 239.0
HKD1_k127_2350726_25 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000124 236.0
HKD1_k127_2350726_26 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000001809 208.0
HKD1_k127_2350726_27 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000004323 192.0
HKD1_k127_2350726_28 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000000002545 174.0
HKD1_k127_2350726_29 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000005569 158.0
HKD1_k127_2350726_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 540.0
HKD1_k127_2350726_30 ATP-dependent protease La (LON) substrate-binding domain K01338 - 3.4.21.53 0.0000000000000000000000000000000000000001133 159.0
HKD1_k127_2350726_31 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000009046 162.0
HKD1_k127_2350726_32 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000002833 150.0
HKD1_k127_2350726_33 DinB superfamily - - - 0.000000000000000000000000000000000001526 143.0
HKD1_k127_2350726_34 SMI1-KNR4 cell-wall - - - 0.0000000000000000000000000000000005363 135.0
HKD1_k127_2350726_35 RNA recognition motif - - - 0.000000000000000000000000000000001302 133.0
HKD1_k127_2350726_36 membrane protein (homolog of Drosophila rhomboid) K19225 - 3.4.21.105 0.0000000000000000000000000000000101 139.0
HKD1_k127_2350726_37 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000003628 102.0
HKD1_k127_2350726_38 cheY-homologous receiver domain - - - 0.000000000000000007718 100.0
HKD1_k127_2350726_39 - - - - 0.00000000000000002605 86.0
HKD1_k127_2350726_4 proline dipeptidase activity K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 511.0
HKD1_k127_2350726_40 - - - - 0.00000003718 59.0
HKD1_k127_2350726_41 chemotaxis K02659,K03408 - - 0.0002925 52.0
HKD1_k127_2350726_5 PFAM Adenosine AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 485.0
HKD1_k127_2350726_6 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009921 473.0
HKD1_k127_2350726_7 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 456.0
HKD1_k127_2350726_8 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 455.0
HKD1_k127_2350726_9 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 452.0
HKD1_k127_2376104_0 Protein of unknown function (DUF3604) - - - 0.0 1056.0
HKD1_k127_2376104_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 4.161e-268 835.0
HKD1_k127_2376104_10 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 370.0
HKD1_k127_2376104_11 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 338.0
HKD1_k127_2376104_12 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 338.0
HKD1_k127_2376104_13 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 310.0
HKD1_k127_2376104_14 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 295.0
HKD1_k127_2376104_15 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004271 275.0
HKD1_k127_2376104_16 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000001255 250.0
HKD1_k127_2376104_17 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002463 225.0
HKD1_k127_2376104_18 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000005447 195.0
HKD1_k127_2376104_19 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000003674 179.0
HKD1_k127_2376104_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 7.607e-255 801.0
HKD1_k127_2376104_20 Protein of unknown function (DUF4239) - - - 0.0000000000000000000000000000000000000000000000263 181.0
HKD1_k127_2376104_21 Beta-lactamase - - - 0.000000000000000000000000000000000000876 154.0
HKD1_k127_2376104_23 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000000000000001005 139.0
HKD1_k127_2376104_24 cheY-homologous receiver domain - - - 0.00000000000000000000000000001169 124.0
HKD1_k127_2376104_25 Protein of unknown function (DUF2490) - - - 0.0000000000000000000006752 105.0
HKD1_k127_2376104_26 - - - - 0.0000000000000007582 86.0
HKD1_k127_2376104_27 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000004708 69.0
HKD1_k127_2376104_28 Putative MetA-pathway of phenol degradation - - - 0.000000000007541 71.0
HKD1_k127_2376104_29 Tricorn protease C1 domain K08676 - - 0.0000003093 52.0
HKD1_k127_2376104_3 serine threonine protein kinase K12132 - 2.7.11.1 8.602e-243 782.0
HKD1_k127_2376104_30 WD40-like Beta Propeller Repeat - - - 0.00001749 48.0
HKD1_k127_2376104_4 COG3653 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 4.713e-213 676.0
HKD1_k127_2376104_5 tRNA synthetases class I (E and Q), catalytic domain K01885 - 6.1.1.17 6.687e-199 633.0
HKD1_k127_2376104_6 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 605.0
HKD1_k127_2376104_7 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 582.0
HKD1_k127_2376104_8 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 596.0
HKD1_k127_2376104_9 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 473.0
HKD1_k127_2380324_0 Carboxypeptidase regulatory-like domain - - - 1.591e-252 815.0
HKD1_k127_2380324_1 Domain of unknown function (DUF3472) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 500.0
HKD1_k127_2380324_10 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000001092 183.0
HKD1_k127_2380324_11 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000004971 133.0
HKD1_k127_2380324_12 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.0000000000000211 77.0
HKD1_k127_2380324_13 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000004952 75.0
HKD1_k127_2380324_14 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000823 67.0
HKD1_k127_2380324_17 - - - - 0.00002493 53.0
HKD1_k127_2380324_18 Bacterial regulatory protein, Fis family K02667 - - 0.00006021 50.0
HKD1_k127_2380324_19 endoribonuclease L-PSP - - - 0.00007549 48.0
HKD1_k127_2380324_2 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 494.0
HKD1_k127_2380324_20 Membrane transport protein - - - 0.00008775 46.0
HKD1_k127_2380324_4 Transcriptional regulator K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 310.0
HKD1_k127_2380324_5 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000005107 240.0
HKD1_k127_2380324_7 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000005911 216.0
HKD1_k127_2380324_8 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000007547 206.0
HKD1_k127_2380324_9 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000002336 185.0
HKD1_k127_2473648_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.576e-252 803.0
HKD1_k127_2473648_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.516e-222 697.0
HKD1_k127_2473648_10 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 417.0
HKD1_k127_2473648_11 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 395.0
HKD1_k127_2473648_12 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 379.0
HKD1_k127_2473648_13 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 380.0
HKD1_k127_2473648_14 amino acid K03294,K13868 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 383.0
HKD1_k127_2473648_15 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 381.0
HKD1_k127_2473648_16 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 GO:0000502,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017171,GO:0019538,GO:0019899,GO:0030163,GO:0031597,GO:0032991,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051117,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 297.0
HKD1_k127_2473648_17 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 310.0
HKD1_k127_2473648_18 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004514 280.0
HKD1_k127_2473648_19 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000001238 214.0
HKD1_k127_2473648_2 TonB-dependent receptor - - - 4.429e-220 719.0
HKD1_k127_2473648_20 DNA-templated transcription, initiation K02405 - - 0.000000000000000000000000000000000000000000000000000000003834 206.0
HKD1_k127_2473648_21 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000002464 193.0
HKD1_k127_2473648_22 - - - - 0.000000000000000000000000000000000000001564 151.0
HKD1_k127_2473648_23 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000002256 140.0
HKD1_k127_2473648_24 GYD domain - - - 0.000000000000000000000000005088 112.0
HKD1_k127_2473648_27 - - - - 0.0008996 43.0
HKD1_k127_2473648_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 603.0
HKD1_k127_2473648_4 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 567.0
HKD1_k127_2473648_5 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 577.0
HKD1_k127_2473648_6 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 550.0
HKD1_k127_2473648_7 beta-N-acetylhexosaminidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 508.0
HKD1_k127_2473648_8 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 475.0
HKD1_k127_2473648_9 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 416.0
HKD1_k127_2511082_0 PFAM NHL repeat containing protein - - - 0.0 1540.0
HKD1_k127_2511082_1 elongator protein 3 miab nifb - - - 3.139e-250 784.0
HKD1_k127_2511082_2 protein tyrosine kinase activity K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 362.0
HKD1_k127_2511082_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000007743 173.0
HKD1_k127_2511082_4 Iron-sulphur cluster biosynthesis - - - 0.0000000000000000000000000000000001716 136.0
HKD1_k127_2511082_5 ribosomal small subunit biogenesis K02945,K03527 - 1.17.7.4 0.000000000000000000000001218 108.0
HKD1_k127_2511082_6 Calx-beta domain - - - 0.00000000000000009796 97.0
HKD1_k127_2511082_7 Adenylate cyclase - - - 0.000000000000001056 89.0
HKD1_k127_2511082_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000002968 79.0
HKD1_k127_2549884_0 TIGRFAM FeS assembly protein SufB K09014 - - 6.095e-253 786.0
HKD1_k127_2549884_1 Amino acid permease - - - 4.921e-199 640.0
HKD1_k127_2549884_10 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000003051 221.0
HKD1_k127_2549884_11 NifU-like N terminal domain K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000009201 201.0
HKD1_k127_2549884_12 Transcriptional regulator - - - 0.00000000000000000000000001089 115.0
HKD1_k127_2549884_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 578.0
HKD1_k127_2549884_3 Acts as a magnesium transporter K06213 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 432.0
HKD1_k127_2549884_4 ATPase activity K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 381.0
HKD1_k127_2549884_5 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 336.0
HKD1_k127_2549884_6 neuron death in response to oxidative stress K01173,K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 358.0
HKD1_k127_2549884_7 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 342.0
HKD1_k127_2549884_8 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 306.0
HKD1_k127_2549884_9 response regulator, receiver K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 285.0
HKD1_k127_2601911_0 Replicative DNA helicase K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 436.0
HKD1_k127_2601911_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 336.0
HKD1_k127_2883_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.213e-221 695.0
HKD1_k127_2883_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 616.0
HKD1_k127_2883_10 BON domain - - - 0.0000000000000000000000000000000000000000001771 168.0
HKD1_k127_2883_11 Chase2 domain - - - 0.00002995 55.0
HKD1_k127_2883_2 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 524.0
HKD1_k127_2883_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008463 401.0
HKD1_k127_2883_4 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 382.0
HKD1_k127_2883_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 317.0
HKD1_k127_2883_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003638 287.0
HKD1_k127_2883_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002545 229.0
HKD1_k127_2883_8 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000009047 207.0
HKD1_k127_2883_9 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000001142 194.0
HKD1_k127_3032381_0 SMART Elongator protein 3 MiaB NifB - - - 1.177e-223 704.0
HKD1_k127_3032381_1 Beta propeller domain - - - 2.033e-216 691.0
HKD1_k127_3032381_10 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 432.0
HKD1_k127_3032381_11 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 405.0
HKD1_k127_3032381_12 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 400.0
HKD1_k127_3032381_13 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 414.0
HKD1_k127_3032381_14 Transporter-associated region K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 396.0
HKD1_k127_3032381_15 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 344.0
HKD1_k127_3032381_16 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 341.0
HKD1_k127_3032381_17 Tim44 K15539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 327.0
HKD1_k127_3032381_18 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 309.0
HKD1_k127_3032381_19 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001611 282.0
HKD1_k127_3032381_2 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 1.479e-198 635.0
HKD1_k127_3032381_20 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001318 290.0
HKD1_k127_3032381_21 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004286 272.0
HKD1_k127_3032381_22 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009134 263.0
HKD1_k127_3032381_23 Transporter, small conductance mechanosensitive ion channel MscS family protein K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000006931 246.0
HKD1_k127_3032381_24 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000828 246.0
HKD1_k127_3032381_25 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000001356 220.0
HKD1_k127_3032381_26 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000009008 210.0
HKD1_k127_3032381_27 Zn-dependent hydrolase, glyoxylase - - - 0.00000000000000000000000000000000000000000000000000001807 200.0
HKD1_k127_3032381_28 - - - - 0.000000000000000000000000000000000000000000000000008545 190.0
HKD1_k127_3032381_29 - - - - 0.0000000000000000000000000000000000000000000008138 171.0
HKD1_k127_3032381_3 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 542.0
HKD1_k127_3032381_30 DinB family - - - 0.00000000000000000000000000000000000000000001783 167.0
HKD1_k127_3032381_31 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000001846 177.0
HKD1_k127_3032381_32 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000003418 160.0
HKD1_k127_3032381_33 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000001718 154.0
HKD1_k127_3032381_34 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000003757 149.0
HKD1_k127_3032381_35 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000000000000001392 145.0
HKD1_k127_3032381_36 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000004098 141.0
HKD1_k127_3032381_37 STAS domain K04749 - - 0.000000000000000000000000000000000006651 139.0
HKD1_k127_3032381_38 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000001327 141.0
HKD1_k127_3032381_39 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000003292 152.0
HKD1_k127_3032381_4 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 538.0
HKD1_k127_3032381_40 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000000531 133.0
HKD1_k127_3032381_41 beta-lactamase domain protein - - - 0.00000000000000000000000000000001794 136.0
HKD1_k127_3032381_42 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000001557 134.0
HKD1_k127_3032381_43 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000001119 109.0
HKD1_k127_3032381_44 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000002437 108.0
HKD1_k127_3032381_45 Transglycosylase associated protein - - - 0.00000000000000000000002184 102.0
HKD1_k127_3032381_46 ABC-2 family transporter protein K01992 - - 0.00000000000000000000558 103.0
HKD1_k127_3032381_47 membrane K08988 - - 0.000000000000000002687 93.0
HKD1_k127_3032381_48 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000005115 79.0
HKD1_k127_3032381_49 Protein of unknown function (DUF1349) - - - 0.0000000000003411 83.0
HKD1_k127_3032381_5 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 501.0
HKD1_k127_3032381_50 - - - - 0.0000000000006272 81.0
HKD1_k127_3032381_51 Putative addiction module component - - - 0.0000000000008059 70.0
HKD1_k127_3032381_52 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000003615 70.0
HKD1_k127_3032381_53 Beta-galactosidase - - - 0.000000008614 68.0
HKD1_k127_3032381_54 - - - - 0.0000005002 62.0
HKD1_k127_3032381_55 Endonuclease/Exonuclease/phosphatase family - - - 0.000002568 59.0
HKD1_k127_3032381_56 endonuclease - - - 0.0000148 57.0
HKD1_k127_3032381_57 Uncharacterised nucleotidyltransferase - - - 0.00001953 56.0
HKD1_k127_3032381_58 Domain of unknown function (DUF4159) - - - 0.00004129 50.0
HKD1_k127_3032381_6 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 481.0
HKD1_k127_3032381_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 453.0
HKD1_k127_3032381_8 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 475.0
HKD1_k127_3032381_9 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 415.0
HKD1_k127_3035579_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 351.0
HKD1_k127_3035579_1 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 348.0
HKD1_k127_3035579_10 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000009542 59.0
HKD1_k127_3035579_2 SPTR Phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001186 271.0
HKD1_k127_3035579_3 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001049 271.0
HKD1_k127_3035579_4 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000007336 239.0
HKD1_k127_3035579_5 Parallel beta-helix repeats K12287 - - 0.0000000000000000000000000000000000000000000000000000008914 218.0
HKD1_k127_3035579_6 iron-sulfur cluster assembly - - - 0.00000000000000000000000000000000000000000000000001014 186.0
HKD1_k127_3035579_7 Large extracellular alpha-helical protein K09607 - - 0.00000000000000000000000000000000003438 155.0
HKD1_k127_3035579_8 COG3420 Nitrous oxidase accessory protein - - - 0.000000000000000000000000000000001291 144.0
HKD1_k127_3035579_9 amine dehydrogenase activity K01448,K07004,K13735,K20276,K21449 - 3.5.1.28 0.00000008329 67.0
HKD1_k127_3105809_0 Heavy metal translocating P-type atpase - - - 4.024e-240 757.0
HKD1_k127_3105809_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 539.0
HKD1_k127_3105809_2 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 469.0
HKD1_k127_3105809_3 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 454.0
HKD1_k127_3105809_4 CHASE3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 395.0
HKD1_k127_3105809_5 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003126 268.0
HKD1_k127_3105809_6 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000001634 104.0
HKD1_k127_3105809_7 SPTR Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein K07005 - - 0.00000000000000000001104 99.0
HKD1_k127_3136975_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 572.0
HKD1_k127_3136975_1 GHMP kinase domain protein K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 472.0
HKD1_k127_3136975_10 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000001387 208.0
HKD1_k127_3136975_11 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000003799 212.0
HKD1_k127_3136975_12 NHL repeat - - - 0.00000000000000000000000000000000000000000002353 186.0
HKD1_k127_3136975_13 NHL repeat - - - 0.0000000000000000000000000000000000000000008187 179.0
HKD1_k127_3136975_14 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000009978 178.0
HKD1_k127_3136975_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000002719 153.0
HKD1_k127_3136975_17 - - - - 0.000000000000000000000000000000000001309 155.0
HKD1_k127_3136975_18 chaperone-mediated protein folding - - - 0.00000000000000000000002082 117.0
HKD1_k127_3136975_19 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000002746 76.0
HKD1_k127_3136975_2 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 425.0
HKD1_k127_3136975_20 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000135 61.0
HKD1_k127_3136975_3 integrase domain protein SAM domain protein K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 400.0
HKD1_k127_3136975_4 PFAM Transaldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 316.0
HKD1_k127_3136975_5 PFAM UvrB UvrC protein K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 310.0
HKD1_k127_3136975_6 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 304.0
HKD1_k127_3136975_7 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 305.0
HKD1_k127_3152399_0 Protein kinase domain K12132 - 2.7.11.1 7.672e-248 796.0
HKD1_k127_3152399_1 glutamate--cysteine ligase - - - 3.197e-232 735.0
HKD1_k127_3152399_10 PFAM Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 418.0
HKD1_k127_3152399_11 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 392.0
HKD1_k127_3152399_12 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 377.0
HKD1_k127_3152399_13 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 365.0
HKD1_k127_3152399_14 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 329.0
HKD1_k127_3152399_15 Inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 329.0
HKD1_k127_3152399_16 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000005537 267.0
HKD1_k127_3152399_17 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000002544 255.0
HKD1_k127_3152399_18 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004103 243.0
HKD1_k127_3152399_19 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000006264 233.0
HKD1_k127_3152399_2 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 5.702e-223 699.0
HKD1_k127_3152399_20 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000006911 234.0
HKD1_k127_3152399_21 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000002053 231.0
HKD1_k127_3152399_22 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000002676 230.0
HKD1_k127_3152399_23 RNA polymerase, sigma-24 subunit, ECF subfamily K02405 - - 0.0000000000000000000000000000000000000000000000000000000006889 207.0
HKD1_k127_3152399_24 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000001046 207.0
HKD1_k127_3152399_25 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000001741 203.0
HKD1_k127_3152399_26 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000379 204.0
HKD1_k127_3152399_27 Metallo-beta-lactamase superfamily - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 - 0.0000000000000000000000000000000000000000000000000002825 192.0
HKD1_k127_3152399_29 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000938 138.0
HKD1_k127_3152399_3 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 500.0
HKD1_k127_3152399_30 von Willebrand factor, type A - - - 0.0000000000000000000000000002768 128.0
HKD1_k127_3152399_32 Protein of unknown function (DUF3455) - - - 0.0000000000000000000000003579 111.0
HKD1_k127_3152399_33 Domain of unknown function (DUF4440) - - - 0.0003251 52.0
HKD1_k127_3152399_34 - - - - 0.0003888 47.0
HKD1_k127_3152399_4 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 490.0
HKD1_k127_3152399_5 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 483.0
HKD1_k127_3152399_6 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 467.0
HKD1_k127_3152399_7 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 464.0
HKD1_k127_3152399_8 inositol monophosphate 1-phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 433.0
HKD1_k127_3152399_9 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 422.0
HKD1_k127_3177648_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 608.0
HKD1_k127_3177648_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 521.0
HKD1_k127_3177648_10 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002836 246.0
HKD1_k127_3177648_11 Ndr family - - - 0.00000000000000000000000000000000000000000000000000000000000009134 224.0
HKD1_k127_3177648_12 conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000000005286 222.0
HKD1_k127_3177648_13 Uncharacterised conserved protein (DUF2156) K14205 - 2.3.2.3 0.0000000000000000000000000000000000000000000006164 181.0
HKD1_k127_3177648_14 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000002439 164.0
HKD1_k127_3177648_15 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000001812 158.0
HKD1_k127_3177648_16 light absorption K01822 - 5.3.3.1 0.00000000000000000000000000000001309 131.0
HKD1_k127_3177648_17 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000002935 130.0
HKD1_k127_3177648_18 IMP dehydrogenase activity - - - 0.0000000000000000000000008546 109.0
HKD1_k127_3177648_19 - - - - 0.00000000000000000005 101.0
HKD1_k127_3177648_2 dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 461.0
HKD1_k127_3177648_20 transglycosylase K08309 - - 0.0000000000000000008498 100.0
HKD1_k127_3177648_21 PFAM Methyltransferase type 11 - - - 0.00000000009194 71.0
HKD1_k127_3177648_22 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.0000000002616 68.0
HKD1_k127_3177648_23 - - - - 0.000007015 52.0
HKD1_k127_3177648_3 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 398.0
HKD1_k127_3177648_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 376.0
HKD1_k127_3177648_5 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 371.0
HKD1_k127_3177648_6 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 307.0
HKD1_k127_3177648_7 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008666 313.0
HKD1_k127_3177648_8 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 314.0
HKD1_k127_3177648_9 Beta-lactamase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001592 257.0
HKD1_k127_3188942_0 DinB superfamily - - - 0.0000000000000000000000000000000000000001378 159.0
HKD1_k127_3188942_1 Ferredoxin - - - 0.000000000000000000000000000000023 130.0
HKD1_k127_3188942_2 Protein of unknown function (DUF1353) - - - 0.00000000000000000000000000000002545 137.0
HKD1_k127_3188942_3 transcription regulator containing HTH domain - - - 0.00000000000000000007823 91.0
HKD1_k127_3188942_4 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000001424 94.0
HKD1_k127_3196365_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 498.0
HKD1_k127_3196365_1 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 404.0
HKD1_k127_3196365_10 hydrolase, family 65, central catalytic K21302 - 3.1.3.64 0.0000000000000009571 92.0
HKD1_k127_3196365_11 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000003475 87.0
HKD1_k127_3196365_12 Protein of unknown function (DUF3383) - - - 0.00007907 57.0
HKD1_k127_3196365_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 293.0
HKD1_k127_3196365_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006336 281.0
HKD1_k127_3196365_4 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000002799 213.0
HKD1_k127_3196365_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000002274 156.0
HKD1_k127_3196365_6 domain, Protein - - - 0.0000000000000000000000000000000000004551 162.0
HKD1_k127_3196365_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000009634 122.0
HKD1_k127_3196365_8 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000002508 100.0
HKD1_k127_3196365_9 Belongs to the UPF0109 family K06960 - - 0.00000000000000003527 85.0
HKD1_k127_3257766_0 Major facilitator Superfamily K03292,K16248 - - 1.499e-230 722.0
HKD1_k127_3257766_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 602.0
HKD1_k127_3257766_10 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000001776 186.0
HKD1_k127_3257766_11 Belongs to the TPP enzyme family - - - 0.00000000000000000000000000000000000000000000004285 194.0
HKD1_k127_3257766_12 - - - - 0.000000000000000000000000000000000002553 141.0
HKD1_k127_3257766_13 pathogenesis - - - 0.0000000000000000000000000000001048 144.0
HKD1_k127_3257766_14 RNA recognition motif - - - 0.0000000000000000000000000000006041 124.0
HKD1_k127_3257766_15 response regulator - - - 0.0000000000000000000000000004161 127.0
HKD1_k127_3257766_16 hydrolase, family 3 K05349 - 3.2.1.21 0.000000000000000000000000277 106.0
HKD1_k127_3257766_17 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000173 104.0
HKD1_k127_3257766_18 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000003329 65.0
HKD1_k127_3257766_19 Belongs to the pirin family K06911 - - 0.000000261 53.0
HKD1_k127_3257766_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 556.0
HKD1_k127_3257766_20 Reductase C-terminal - - - 0.0001541 48.0
HKD1_k127_3257766_21 Histidine kinase K20974 - 2.7.13.3 0.0003759 49.0
HKD1_k127_3257766_3 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 508.0
HKD1_k127_3257766_4 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 492.0
HKD1_k127_3257766_5 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 481.0
HKD1_k127_3257766_6 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 385.0
HKD1_k127_3257766_7 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 335.0
HKD1_k127_3257766_8 SMART HTH transcriptional regulator, Crp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 302.0
HKD1_k127_3257766_9 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000006022 264.0
HKD1_k127_3266519_0 lipopolysaccharide transport K22110 - - 0.0 1446.0
HKD1_k127_3266519_1 Glycogen debranching enzyme - - - 1.655e-234 743.0
HKD1_k127_3266519_10 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 411.0
HKD1_k127_3266519_11 Evidence 2b Function of strongly homologous gene K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 406.0
HKD1_k127_3266519_12 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 386.0
HKD1_k127_3266519_13 Belongs to the Pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 377.0
HKD1_k127_3266519_14 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 376.0
HKD1_k127_3266519_15 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 368.0
HKD1_k127_3266519_16 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 347.0
HKD1_k127_3266519_17 PFAM Glycosyl transferase family 2 K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 332.0
HKD1_k127_3266519_18 PFAM UbiA prenyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 331.0
HKD1_k127_3266519_19 G-rich domain on putative tyrosine kinase K08252,K16554 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 346.0
HKD1_k127_3266519_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 611.0
HKD1_k127_3266519_20 PRMT5 arginine-N-methyltransferase K11434 - 2.1.1.319 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 322.0
HKD1_k127_3266519_21 PFAM ThiJ PfpI - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 318.0
HKD1_k127_3266519_22 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003292 263.0
HKD1_k127_3266519_23 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000659 233.0
HKD1_k127_3266519_24 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000002702 226.0
HKD1_k127_3266519_25 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000003822 210.0
HKD1_k127_3266519_26 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000005345 202.0
HKD1_k127_3266519_27 Glycosyl transferase family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000004301 193.0
HKD1_k127_3266519_28 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000239 166.0
HKD1_k127_3266519_29 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000003253 175.0
HKD1_k127_3266519_3 PFAM DegT DnrJ EryC1 StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 578.0
HKD1_k127_3266519_30 - - - - 0.0000000000000000000000000000000000000000001995 162.0
HKD1_k127_3266519_31 PFAM Glycosyl transferase, group 1 K12996 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000001051 167.0
HKD1_k127_3266519_32 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000002379 162.0
HKD1_k127_3266519_33 Kelch motif - - - 0.000000000000000000000000000000000004724 160.0
HKD1_k127_3266519_34 methyltransferase K15471 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000007844 147.0
HKD1_k127_3266519_35 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000002845 146.0
HKD1_k127_3266519_36 O-Antigen ligase K02847 - - 0.0000000000000000000000000000000005728 147.0
HKD1_k127_3266519_37 RNA recognition motif - - - 0.00000000000000000000000000000009554 127.0
HKD1_k127_3266519_38 - - - - 0.000000000000000000000000000001701 139.0
HKD1_k127_3266519_39 alginic acid biosynthetic process - - - 0.000000000000000000000000000003452 141.0
HKD1_k127_3266519_4 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 556.0
HKD1_k127_3266519_40 - - - - 0.00000000000000000000000000001156 124.0
HKD1_k127_3266519_41 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000000000000002703 132.0
HKD1_k127_3266519_42 SLBB domain K01991 - - 0.0000000000000000000000000003507 126.0
HKD1_k127_3266519_43 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000002179 122.0
HKD1_k127_3266519_44 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000002885 103.0
HKD1_k127_3266519_45 Putative metal-binding motif - - - 0.0000000000000000000004673 114.0
HKD1_k127_3266519_46 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000002239 104.0
HKD1_k127_3266519_47 Transglutaminase-like superfamily - - - 0.0000000000000000006117 92.0
HKD1_k127_3266519_48 Methionine biosynthesis protein MetW - - - 0.0000000000000003345 88.0
HKD1_k127_3266519_49 Pkd domain containing protein - - - 0.00000000004599 78.0
HKD1_k127_3266519_5 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 545.0
HKD1_k127_3266519_50 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000002805 68.0
HKD1_k127_3266519_51 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000002817 74.0
HKD1_k127_3266519_52 Amidohydrolase family - - - 0.000000002994 59.0
HKD1_k127_3266519_53 - - - - 0.000000387 56.0
HKD1_k127_3266519_54 Tetratricopeptide repeat - - - 0.00001123 50.0
HKD1_k127_3266519_55 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.00001237 58.0
HKD1_k127_3266519_56 peroxisome matrix targeting signal-1 binding K13342,K20915 GO:0000038,GO:0000268,GO:0001764,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0005048,GO:0005052,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005782,GO:0005794,GO:0005829,GO:0006082,GO:0006464,GO:0006605,GO:0006612,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006807,GO:0006810,GO:0006886,GO:0006928,GO:0006996,GO:0007005,GO:0007006,GO:0007029,GO:0007031,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008022,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009791,GO:0009987,GO:0010256,GO:0012505,GO:0015031,GO:0015833,GO:0015919,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016477,GO:0016558,GO:0016560,GO:0016561,GO:0016567,GO:0017038,GO:0019395,GO:0019538,GO:0019752,GO:0019899,GO:0021537,GO:0021543,GO:0021795,GO:0021885,GO:0021895,GO:0021953,GO:0021987,GO:0022008,GO:0022029,GO:0022607,GO:0030154,GO:0030182,GO:0030258,GO:0030900,GO:0031090,GO:0031267,GO:0031333,GO:0031903,GO:0031907,GO:0031974,GO:0032446,GO:0032459,GO:0032460,GO:0032462,GO:0032463,GO:0032501,GO:0032502,GO:0032787,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034440,GO:0034613,GO:0036211,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042277,GO:0042493,GO:0042579,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043254,GO:0043412,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0045046,GO:0045184,GO:0045927,GO:0046395,GO:0046907,GO:0047485,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048523,GO:0048638,GO:0048639,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050896,GO:0050905,GO:0051020,GO:0051094,GO:0051128,GO:0051129,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0051674,GO:0055085,GO:0055114,GO:0060322,GO:0061024,GO:0065002,GO:0065003,GO:0065007,GO:0070013,GO:0070647,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071806,GO:0071840,GO:0072329,GO:0072347,GO:0072594,GO:0072657,GO:0072662,GO:0072663,GO:0090150,GO:0098588,GO:0098805,GO:1901090,GO:1901091,GO:1901093,GO:1901094,GO:1901564,GO:1901575 - 0.00005876 55.0
HKD1_k127_3266519_57 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00007811 55.0
HKD1_k127_3266519_6 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 525.0
HKD1_k127_3266519_7 Polysaccharide biosynthesis protein CapD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 471.0
HKD1_k127_3266519_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 436.0
HKD1_k127_3266519_9 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 422.0
HKD1_k127_3282997_0 COGs COG0076 Glutamate decarboxylase and related PLP-dependent protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008499 544.0
HKD1_k127_3282997_1 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 407.0
HKD1_k127_3282997_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 311.0
HKD1_k127_3282997_3 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000000000000000000000000001898 201.0
HKD1_k127_3282997_4 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000954 205.0
HKD1_k127_3282997_5 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000004201 190.0
HKD1_k127_3282997_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000001984 121.0
HKD1_k127_3282997_7 - - - - 0.0000000000000000000000000001805 117.0
HKD1_k127_3282997_8 - - - - 0.000000000000000000001268 109.0
HKD1_k127_332788_0 Succinyl-CoA ligase like flavodoxin domain - - - 0.0 1025.0
HKD1_k127_332788_1 PFAM aminotransferase, class I K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 537.0
HKD1_k127_332788_10 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000000004412 171.0
HKD1_k127_332788_11 OsmC-like protein - - - 0.00000000000000000000000000000000000002441 149.0
HKD1_k127_332788_12 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.00000000000000000000000000000000008808 141.0
HKD1_k127_332788_13 Urate oxidase N-terminal - - - 0.00000000000000000000000000000001285 137.0
HKD1_k127_332788_14 Rieske [2Fe-2S] domain - - - 0.000000000000000000000001884 109.0
HKD1_k127_332788_15 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000003811 90.0
HKD1_k127_332788_16 - - - - 0.0000000000001837 75.0
HKD1_k127_332788_17 Tetratricopeptide TPR_2 repeat protein - - - 0.0000002783 61.0
HKD1_k127_332788_2 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 460.0
HKD1_k127_332788_3 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 299.0
HKD1_k127_332788_4 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002149 261.0
HKD1_k127_332788_5 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000009661 259.0
HKD1_k127_332788_6 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000714 225.0
HKD1_k127_332788_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000005552 222.0
HKD1_k127_332788_8 - - - - 0.00000000000000000000000000000000000000000000000004763 187.0
HKD1_k127_332788_9 dehydrogenase complex catalyzes the overall conversion of - - - 0.00000000000000000000000000000000000000000000008141 181.0
HKD1_k127_3330122_0 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 7.617e-195 614.0
HKD1_k127_3330122_1 proline dipeptidase activity K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 402.0
HKD1_k127_3330122_10 PFAM PemK-like protein K07171 - - 0.0000000002521 63.0
HKD1_k127_3330122_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 414.0
HKD1_k127_3330122_3 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006761 278.0
HKD1_k127_3330122_4 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000003387 232.0
HKD1_k127_3330122_5 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000000000000000002183 202.0
HKD1_k127_3330122_6 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000008246 172.0
HKD1_k127_3330122_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000005012 175.0
HKD1_k127_3330122_9 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000000000001659 93.0
HKD1_k127_3424823_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1102.0
HKD1_k127_3424823_1 Amidohydrolase family - - - 1.064e-215 681.0
HKD1_k127_3424823_10 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 404.0
HKD1_k127_3424823_11 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 361.0
HKD1_k127_3424823_12 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 320.0
HKD1_k127_3424823_13 PFAM peptidase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 307.0
HKD1_k127_3424823_14 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 304.0
HKD1_k127_3424823_15 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 296.0
HKD1_k127_3424823_16 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004757 285.0
HKD1_k127_3424823_17 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000111 265.0
HKD1_k127_3424823_18 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000001476 239.0
HKD1_k127_3424823_19 COG0436 Aspartate tyrosine aromatic aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000002065 235.0
HKD1_k127_3424823_2 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 5.457e-202 650.0
HKD1_k127_3424823_20 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000008911 230.0
HKD1_k127_3424823_21 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000003725 216.0
HKD1_k127_3424823_22 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000005119 201.0
HKD1_k127_3424823_23 GGDEF domain - - - 0.00000000000000000000000000000000000000000000001308 183.0
HKD1_k127_3424823_24 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000002457 154.0
HKD1_k127_3424823_25 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.0000000000000000000000000000000004829 144.0
HKD1_k127_3424823_26 Protein of unknown function DUF84 - GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564 - 0.0000000000000000000000000707 114.0
HKD1_k127_3424823_27 oxidoreductase activity - - - 0.0000000000000005772 92.0
HKD1_k127_3424823_28 phosphorelay signal transduction system - - - 0.00000000001075 76.0
HKD1_k127_3424823_29 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000222 62.0
HKD1_k127_3424823_3 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 578.0
HKD1_k127_3424823_30 Tetratricopeptide TPR_2 repeat protein - - - 0.0000004417 61.0
HKD1_k127_3424823_31 Chemotaxis protein cheY K03413 - - 0.0000006522 62.0
HKD1_k127_3424823_32 self proteolysis - - - 0.000001478 60.0
HKD1_k127_3424823_33 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00004407 55.0
HKD1_k127_3424823_34 Tetratricopeptide repeat - - - 0.0003127 52.0
HKD1_k127_3424823_4 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 517.0
HKD1_k127_3424823_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 477.0
HKD1_k127_3424823_6 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 466.0
HKD1_k127_3424823_7 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 436.0
HKD1_k127_3424823_8 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 405.0
HKD1_k127_3424823_9 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 386.0
HKD1_k127_3432393_0 cellulose binding - - - 0.0 1369.0
HKD1_k127_3432393_1 Alpha/beta hydrolase family - - - 5.163e-288 901.0
HKD1_k127_3432393_10 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 295.0
HKD1_k127_3432393_11 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001529 260.0
HKD1_k127_3432393_12 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000004026 220.0
HKD1_k127_3432393_13 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000005888 214.0
HKD1_k127_3432393_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000489 192.0
HKD1_k127_3432393_15 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000001709 148.0
HKD1_k127_3432393_16 Cupredoxin-like domain K02275 - 1.9.3.1 0.00000000000000000000000000000001792 130.0
HKD1_k127_3432393_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000002641 110.0
HKD1_k127_3432393_19 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000002835 103.0
HKD1_k127_3432393_2 TIGRFAM L-lactate transport K03303 - - 7.354e-240 752.0
HKD1_k127_3432393_20 Histidine kinase-like ATPases - - - 0.000000000000000002989 89.0
HKD1_k127_3432393_21 lipid binding K03098 - - 0.000000000000000007995 88.0
HKD1_k127_3432393_22 SnoaL-like domain - - - 0.00002658 55.0
HKD1_k127_3432393_23 - - - - 0.000251 53.0
HKD1_k127_3432393_3 tagaturonate epimerase K21619 - 5.1.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 605.0
HKD1_k127_3432393_4 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 604.0
HKD1_k127_3432393_5 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 539.0
HKD1_k127_3432393_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 420.0
HKD1_k127_3432393_7 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 382.0
HKD1_k127_3432393_8 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 386.0
HKD1_k127_3432393_9 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 357.0
HKD1_k127_3433957_0 ABC transporter transmembrane region K06147 - - 3.023e-209 674.0
HKD1_k127_3433957_1 pyrroloquinoline quinone binding K01206,K01218 - 3.2.1.51,3.2.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 625.0
HKD1_k127_3433957_10 cell redox homeostasis - - - 0.00000000000000000000000000000000000000001364 163.0
HKD1_k127_3433957_11 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000008753 107.0
HKD1_k127_3433957_12 GAF domain - - - 0.0000000002324 70.0
HKD1_k127_3433957_13 - - - - 0.00000001886 65.0
HKD1_k127_3433957_2 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 587.0
HKD1_k127_3433957_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 344.0
HKD1_k127_3433957_4 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001598 258.0
HKD1_k127_3433957_5 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000002615 238.0
HKD1_k127_3433957_6 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000007271 225.0
HKD1_k127_3433957_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000001006 222.0
HKD1_k127_3433957_8 membrane - - - 0.00000000000000000000000000000000000000000000000001579 199.0
HKD1_k127_3433957_9 - - - - 0.0000000000000000000000000000000000000000000001593 176.0
HKD1_k127_3574582_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 362.0
HKD1_k127_3574582_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 294.0
HKD1_k127_3574582_2 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000001404 215.0
HKD1_k127_3574582_3 bacterial-type flagellum organization K02282,K04562 - - 0.00000000000000000000000000000000000000000000000001382 195.0
HKD1_k127_3574582_4 - - - - 0.0000000000000000000000000000000000000000000001117 190.0
HKD1_k127_3574582_5 Ubiquinone biosynthesis methyltransferase UbiE K07755 - 2.1.1.137 0.00000000000000004842 90.0
HKD1_k127_3685313_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 574.0
HKD1_k127_3685313_1 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 393.0
HKD1_k127_3685313_2 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 333.0
HKD1_k127_3685313_3 imidazolonepropionase activity K00466 - 1.13.12.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 314.0
HKD1_k127_3685313_4 COG1956 GAF domain-containing protein K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000000000000000000001182 221.0
HKD1_k127_3685313_5 WG containing repeat - - - 0.000000000000000000000000000000000000000000000000002927 195.0
HKD1_k127_3685313_6 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000002306 78.0
HKD1_k127_3685313_7 histidine kinase A domain protein - - - 0.000007631 54.0
HKD1_k127_3771014_0 Cytochrome c - - - 4.781e-308 983.0
HKD1_k127_3771014_1 Cytochrome c-type biogenesis protein CcmF K02198 - - 1.589e-299 932.0
HKD1_k127_3771014_10 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 302.0
HKD1_k127_3771014_11 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002216 278.0
HKD1_k127_3771014_12 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001339 280.0
HKD1_k127_3771014_13 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000583 263.0
HKD1_k127_3771014_14 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007004 262.0
HKD1_k127_3771014_15 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000008992 254.0
HKD1_k127_3771014_16 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000001174 239.0
HKD1_k127_3771014_17 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000002356 234.0
HKD1_k127_3771014_18 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000007999 232.0
HKD1_k127_3771014_19 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000003474 218.0
HKD1_k127_3771014_2 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 1.54e-196 630.0
HKD1_k127_3771014_20 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000002735 203.0
HKD1_k127_3771014_21 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000003073 196.0
HKD1_k127_3771014_22 Tetratricopeptide repeat K02200 - - 0.00000000000000000000000000000000000000000000000001962 191.0
HKD1_k127_3771014_23 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000003056 166.0
HKD1_k127_3771014_24 heme a metabolic process K02259,K03110 - - 0.000000000000000000000000000000000000000005112 168.0
HKD1_k127_3771014_25 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000001334 136.0
HKD1_k127_3771014_26 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000008402 130.0
HKD1_k127_3771014_29 - - - - 0.000000000000000000009395 98.0
HKD1_k127_3771014_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 614.0
HKD1_k127_3771014_31 Protein of unknown function (DUF1059) - - - 0.0000000000000003663 81.0
HKD1_k127_3771014_32 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000000001874 71.0
HKD1_k127_3771014_33 cell redox homeostasis K03671 - - 0.000000000002146 70.0
HKD1_k127_3771014_34 Evidence 4 Homologs of previously reported genes of K03975 - - 0.00000000006939 69.0
HKD1_k127_3771014_35 Adenylate cyclase - - - 0.00001639 54.0
HKD1_k127_3771014_4 TIGRFAM magnesium chelatase, H subunit K03403 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 514.0
HKD1_k127_3771014_5 PFAM CobN Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 511.0
HKD1_k127_3771014_6 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 494.0
HKD1_k127_3771014_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 465.0
HKD1_k127_3771014_8 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 419.0
HKD1_k127_3771014_9 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 345.0
HKD1_k127_3774502_0 Carboxypeptidase regulatory-like domain - - - 0.0 1443.0
HKD1_k127_3774502_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1296.0
HKD1_k127_3774502_10 abc transporter (atp-binding protein) K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 288.0
HKD1_k127_3774502_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004773 246.0
HKD1_k127_3774502_12 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000003062 188.0
HKD1_k127_3774502_13 PFAM Peptidase family M23 K21472 - - 0.000000000000000000000000000000000000000000000002613 181.0
HKD1_k127_3774502_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000009304 132.0
HKD1_k127_3774502_16 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03767,K03768,K09565 - 5.2.1.8 0.00000000000000000000000000001549 127.0
HKD1_k127_3774502_17 deoxyhypusine monooxygenase activity K05385 - - 0.00000000000000000000000003452 121.0
HKD1_k127_3774502_18 Penicillinase repressor - - - 0.0000000000000000000001491 103.0
HKD1_k127_3774502_19 Uncharacterized protein family UPF0016 - - - 0.00000000000000000001048 99.0
HKD1_k127_3774502_2 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 1.608e-194 618.0
HKD1_k127_3774502_20 cheY-homologous receiver domain - - - 0.00000000000000007819 85.0
HKD1_k127_3774502_21 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000003815 79.0
HKD1_k127_3774502_22 HEAT repeats - - - 0.0000000000002834 83.0
HKD1_k127_3774502_24 - - - - 0.000000001549 64.0
HKD1_k127_3774502_25 Sigma-54 interaction domain - - - 0.00001786 52.0
HKD1_k127_3774502_26 Peptidase family M48 - - - 0.0003644 52.0
HKD1_k127_3774502_27 - - - - 0.0005209 50.0
HKD1_k127_3774502_3 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 441.0
HKD1_k127_3774502_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 410.0
HKD1_k127_3774502_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 392.0
HKD1_k127_3774502_6 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 368.0
HKD1_k127_3774502_7 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 349.0
HKD1_k127_3774502_8 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009676 322.0
HKD1_k127_3774502_9 ABC-type hemin transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 306.0
HKD1_k127_3798560_0 Hydrolase CocE NonD family - - - 0.0 1005.0
HKD1_k127_3798560_1 PFAM ABC transporter related K06020 - 3.6.3.25 6.484e-298 923.0
HKD1_k127_3798560_10 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 591.0
HKD1_k127_3798560_11 oligopeptide transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 543.0
HKD1_k127_3798560_12 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 415.0
HKD1_k127_3798560_13 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 401.0
HKD1_k127_3798560_14 Class II aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 366.0
HKD1_k127_3798560_15 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 347.0
HKD1_k127_3798560_16 Protein of unknown function (DUF4256) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 317.0
HKD1_k127_3798560_17 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 307.0
HKD1_k127_3798560_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001446 237.0
HKD1_k127_3798560_19 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000008268 237.0
HKD1_k127_3798560_2 Beta-L-arabinofuranosidase, GH127 K09955 - - 2.404e-277 873.0
HKD1_k127_3798560_20 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000002128 222.0
HKD1_k127_3798560_21 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000002029 215.0
HKD1_k127_3798560_22 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000007093 210.0
HKD1_k127_3798560_23 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000001565 154.0
HKD1_k127_3798560_24 - - - - 0.00000000000000000000000000004134 128.0
HKD1_k127_3798560_25 Lamin Tail Domain K07004 - - 0.00000000000000000000000000008097 133.0
HKD1_k127_3798560_26 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000001035 123.0
HKD1_k127_3798560_27 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000001771 124.0
HKD1_k127_3798560_28 - - - - 0.000000000000000000000009307 102.0
HKD1_k127_3798560_29 - - - - 0.0000000000000000000001302 107.0
HKD1_k127_3798560_3 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 2.197e-247 784.0
HKD1_k127_3798560_30 domain protein - - - 0.0000000000000000000002831 112.0
HKD1_k127_3798560_31 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000004593 110.0
HKD1_k127_3798560_32 Glyoxalase-like domain - - - 0.0000000000000000000008179 109.0
HKD1_k127_3798560_34 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000000000001485 76.0
HKD1_k127_3798560_35 domain protein K14194 - - 0.0000000000004865 82.0
HKD1_k127_3798560_36 Plectin repeat K10382,K10388,K19827 GO:0000003,GO:0000226,GO:0000235,GO:0000902,GO:0000904,GO:0001558,GO:0001578,GO:0001700,GO:0001709,GO:0001763,GO:0002009,GO:0002020,GO:0002165,GO:0003674,GO:0003779,GO:0004857,GO:0004866,GO:0004869,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005818,GO:0005819,GO:0005829,GO:0005856,GO:0005874,GO:0005876,GO:0005881,GO:0005886,GO:0005903,GO:0005912,GO:0005924,GO:0005925,GO:0005927,GO:0006915,GO:0006928,GO:0006935,GO:0006996,GO:0007010,GO:0007017,GO:0007026,GO:0007044,GO:0007154,GO:0007267,GO:0007275,GO:0007391,GO:0007399,GO:0007409,GO:0007411,GO:0007417,GO:0007420,GO:0007423,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007517,GO:0007552,GO:0007560,GO:0007565,GO:0007584,GO:0008017,GO:0008037,GO:0008038,GO:0008092,GO:0008150,GO:0008219,GO:0008307,GO:0008361,GO:0008587,GO:0009605,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009887,GO:0009888,GO:0009892,GO:0009925,GO:0009987,GO:0009991,GO:0010466,GO:0010468,GO:0010605,GO:0010629,GO:0010639,GO:0010720,GO:0010769,GO:0010770,GO:0010941,GO:0010942,GO:0010951,GO:0010955,GO:0010975,GO:0010976,GO:0012501,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016198,GO:0016199,GO:0016203,GO:0016204,GO:0016319,GO:0016323,GO:0016324,GO:0016331,GO:0016358,GO:0016528,GO:0019222,GO:0019899,GO:0022008,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0023052,GO:0030016,GO:0030029,GO:0030030,GO:0030036,GO:0030054,GO:0030055,GO:0030056,GO:0030154,GO:0030162,GO:0030175,GO:0030182,GO:0030234,GO:0030307,GO:0030414,GO:0030424,GO:0030426,GO:0030427,GO:0030506,GO:0030516,GO:0030716,GO:0030855,GO:0030865,GO:0031110,GO:0031111,GO:0031114,GO:0031122,GO:0031175,GO:0031323,GO:0031324,GO:0031344,GO:0031346,GO:0031581,GO:0031667,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0032886,GO:0032989,GO:0032990,GO:0032991,GO:0033043,GO:0033267,GO:0034329,GO:0034330,GO:0035107,GO:0035114,GO:0035120,GO:0035146,GO:0035147,GO:0035148,GO:0035149,GO:0035152,GO:0035220,GO:0035239,GO:0035295,GO:0035371,GO:0035375,GO:0040008,GO:0040011,GO:0042221,GO:0042330,GO:0042383,GO:0042981,GO:0042995,GO:0043005,GO:0043027,GO:0043028,GO:0043034,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043086,GO:0043154,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043242,GO:0043244,GO:0043281,GO:0043292,GO:0043622,GO:0043900,GO:0043902,GO:0044085,GO:0044087,GO:0044089,GO:0044092,GO:0044295,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044706,GO:0045111,GO:0045165,GO:0045169,GO:0045177,GO:0045178,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045773,GO:0045861,GO:0045927,GO:0047485,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048563,GO:0048569,GO:0048598,GO:0048609,GO:0048638,GO:0048639,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048754,GO:0048812,GO:0048813,GO:0048856,GO:0048858,GO:0048869,GO:0050767,GO:0050769,GO:0050770,GO:0050772,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0051489,GO:0051491,GO:0051493,GO:0051494,GO:0051704,GO:0051960,GO:0051962,GO:0052547,GO:0052548,GO:0060255,GO:0060284,GO:0060322,GO:0060378,GO:0060429,GO:0060446,GO:0060491,GO:0060538,GO:0060541,GO:0060548,GO:0060562,GO:0061061,GO:0061134,GO:0061135,GO:0061138,GO:0061387,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070161,GO:0070507,GO:0070613,GO:0071840,GO:0071944,GO:0080090,GO:0080154,GO:0089720,GO:0090066,GO:0090727,GO:0097179,GO:0097340,GO:0097341,GO:0097435,GO:0097458,GO:0097485,GO:0098590,GO:0098772,GO:0098858,GO:0098862,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0120025,GO:0120032,GO:0120034,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:1901879,GO:1901880,GO:1902903,GO:1902904,GO:1903317,GO:1903318,GO:1904090,GO:1904747,GO:1904748,GO:1905516,GO:1990001,GO:1990752,GO:2000026,GO:2000116,GO:2000117,GO:2000241,GO:2000243 - 0.000001504 63.0
HKD1_k127_3798560_37 to Periplasmic repressor of cpx regulon by interaction with CpxA, rescue from transitory stresses of Enterobacteriaceae UniRef RepID A8GLB2_SERP5 K06006 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051082,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000003005 57.0
HKD1_k127_3798560_4 Carboxypeptidase regulatory-like domain - - - 1.38e-239 775.0
HKD1_k127_3798560_5 N-acetyldiaminopimelate deacetylase activity K12941 - - 1.973e-239 751.0
HKD1_k127_3798560_6 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 2.429e-209 667.0
HKD1_k127_3798560_7 Elongation factor G, domain IV K02355 - - 5.999e-199 642.0
HKD1_k127_3798560_8 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 4.499e-195 619.0
HKD1_k127_3798560_9 hydrolase activity, hydrolyzing O-glycosyl compounds K00689 GO:0005575,GO:0005576 2.4.1.5 2.243e-194 623.0
HKD1_k127_3802551_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 400.0
HKD1_k127_3802551_1 Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000522 226.0
HKD1_k127_3802551_2 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000001759 166.0
HKD1_k127_3802551_3 transcriptional regulator, RpiR family - - - 0.00000000000000001203 94.0
HKD1_k127_3814525_0 CarboxypepD_reg-like domain - - - 6.896e-218 725.0
HKD1_k127_3814525_1 Ftsk_gamma K03466 - - 1.134e-194 634.0
HKD1_k127_3814525_10 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001482 261.0
HKD1_k127_3814525_11 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002559 281.0
HKD1_k127_3814525_12 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000002033 264.0
HKD1_k127_3814525_13 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001766 267.0
HKD1_k127_3814525_14 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001936 261.0
HKD1_k127_3814525_15 Chlorite dismutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001851 247.0
HKD1_k127_3814525_16 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000549 247.0
HKD1_k127_3814525_17 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005385,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006829,GO:0006873,GO:0006875,GO:0006876,GO:0006882,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015086,GO:0015093,GO:0015291,GO:0015318,GO:0015341,GO:0015562,GO:0015684,GO:0015691,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0030003,GO:0034220,GO:0034755,GO:0042592,GO:0042802,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055069,GO:0055073,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070574,GO:0070838,GO:0071577,GO:0071944,GO:0072503,GO:0072507,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:1903874 - 0.000000000000000000000000000000000000000000000000000000008591 210.0
HKD1_k127_3814525_18 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000009403 166.0
HKD1_k127_3814525_19 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000007034 162.0
HKD1_k127_3814525_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 647.0
HKD1_k127_3814525_20 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000002271 155.0
HKD1_k127_3814525_21 Protein of unknown function (DUF2585) - - - 0.00000000000000000000000000000000001714 142.0
HKD1_k127_3814525_22 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000009132 141.0
HKD1_k127_3814525_23 outer membrane autotransporter barrel domain protein - - - 0.00000000000000000000000000000003401 135.0
HKD1_k127_3814525_24 Tetratricopeptide repeat - - - 0.00000000000000000000000000000007593 143.0
HKD1_k127_3814525_25 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.0000000000000000000000004131 111.0
HKD1_k127_3814525_27 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000002976 81.0
HKD1_k127_3814525_28 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.0000000000000008652 85.0
HKD1_k127_3814525_29 TIGRFAM Competence protein ComEA, helix-hairpin-helix K02237 - - 0.000000000000001691 80.0
HKD1_k127_3814525_3 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 606.0
HKD1_k127_3814525_30 TIGRFAM periplasmic serine protease, Do DeqQ family K04771 - 3.4.21.107 0.000000000000006346 88.0
HKD1_k127_3814525_31 - - - - 0.00000000000004859 83.0
HKD1_k127_3814525_32 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000001037 65.0
HKD1_k127_3814525_33 Tetratricopeptide repeat K02656 - - 0.00005427 55.0
HKD1_k127_3814525_34 PFAM IstB domain protein ATP-binding protein - - - 0.0000568 48.0
HKD1_k127_3814525_35 Transposase and inactivated derivatives - - - 0.00009243 46.0
HKD1_k127_3814525_36 hyperosmotic response K04065 - - 0.0001157 51.0
HKD1_k127_3814525_37 Domain of unknown function (DUF4349) - - - 0.000408 52.0
HKD1_k127_3814525_38 Evidence 4 Homologs of previously reported genes of - - - 0.0005554 51.0
HKD1_k127_3814525_4 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 449.0
HKD1_k127_3814525_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 398.0
HKD1_k127_3814525_6 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 394.0
HKD1_k127_3814525_7 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 382.0
HKD1_k127_3814525_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 319.0
HKD1_k127_3814525_9 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 301.0
HKD1_k127_384054_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000381 146.0
HKD1_k127_3878722_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 3.107e-291 919.0
HKD1_k127_3878722_1 belongs to the aldehyde dehydrogenase family K00128,K00154,K22445 - 1.2.1.3,1.2.1.68,1.2.99.10 1.058e-203 642.0
HKD1_k127_3878722_10 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 310.0
HKD1_k127_3878722_11 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 304.0
HKD1_k127_3878722_12 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000008414 252.0
HKD1_k127_3878722_13 - - - - 0.000000000000000000000000000000000000000000000000000001616 197.0
HKD1_k127_3878722_14 Cell wall formation - - - 0.000000000000000000000000000000000000000000000000006048 192.0
HKD1_k127_3878722_15 cellulose binding - - - 0.00000000000000000000000000000000000000000001839 174.0
HKD1_k127_3878722_16 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000002697 153.0
HKD1_k127_3878722_17 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF K07402 - - 0.0000000000000000000000000000000000007868 153.0
HKD1_k127_3878722_18 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000001184 132.0
HKD1_k127_3878722_19 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000005118 134.0
HKD1_k127_3878722_2 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 582.0
HKD1_k127_3878722_20 cheY-homologous receiver domain - - - 0.0000000000000000000000000000002772 139.0
HKD1_k127_3878722_21 XdhC and CoxI family - - - 0.000000000000000000001809 97.0
HKD1_k127_3878722_22 Hfq protein - - - 0.000000000000000000006202 100.0
HKD1_k127_3878722_23 phosphorelay signal transduction system - - - 0.00000000000000004523 85.0
HKD1_k127_3878722_24 Cell division protein FtsQ K03589 - - 0.00000000003298 75.0
HKD1_k127_3878722_25 Domain of unknown function (DUF374) - - - 0.0000000231 64.0
HKD1_k127_3878722_27 Type II secretion system (T2SS), protein G K02456 - - 0.00006573 53.0
HKD1_k127_3878722_3 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 569.0
HKD1_k127_3878722_4 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 584.0
HKD1_k127_3878722_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 526.0
HKD1_k127_3878722_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 412.0
HKD1_k127_3878722_7 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 393.0
HKD1_k127_3878722_8 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 333.0
HKD1_k127_3878722_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 328.0
HKD1_k127_4044628_0 ABC transporter transmembrane region K06147 - - 2.652e-308 976.0
HKD1_k127_4044628_1 Alpha beta hydrolase - GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 598.0
HKD1_k127_4044628_10 cdp-diacylglycerol--glycerol-3-phosphate - - - 0.00000000000000000000000006522 115.0
HKD1_k127_4044628_11 Alternative locus ID K02022 - - 0.00000000000000000001444 104.0
HKD1_k127_4044628_12 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000681 90.0
HKD1_k127_4044628_2 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 421.0
HKD1_k127_4044628_3 Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 361.0
HKD1_k127_4044628_4 Dual specificity phosphatase, catalytic domain K01090 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000004294 263.0
HKD1_k127_4044628_5 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001487 248.0
HKD1_k127_4044628_6 Magnesium chelatase, subunit ChlI - - - 0.000000000000000000000000000000000000000000000000000000000000000001329 239.0
HKD1_k127_4044628_7 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000004519 209.0
HKD1_k127_4044628_8 Acyl-transferase K00655,K01897 - 2.3.1.51,6.2.1.3 0.00000000000000000000000000000000000000004707 164.0
HKD1_k127_4044628_9 - - - - 0.00000000000000000000000001935 113.0
HKD1_k127_4071323_0 Sulfatase - - - 5.423e-221 695.0
HKD1_k127_4071323_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 516.0
HKD1_k127_4071323_2 unsaturated fatty acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 450.0
HKD1_k127_4071323_3 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 333.0
HKD1_k127_4071323_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000008891 202.0
HKD1_k127_4071323_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000447 202.0
HKD1_k127_4071323_7 cheY-homologous receiver domain - - - 0.00000000000000000000000001856 112.0
HKD1_k127_4071323_8 - - - - 0.0000000000000000000000001515 109.0
HKD1_k127_4071323_9 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000002502 106.0
HKD1_k127_4078274_0 competence protein COMEC K02238 - - 3.525e-248 774.0
HKD1_k127_4078274_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 448.0
HKD1_k127_4078274_10 Putative peptidoglycan binding domain - - - 0.0000009124 61.0
HKD1_k127_4078274_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 401.0
HKD1_k127_4078274_3 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 327.0
HKD1_k127_4078274_5 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008448 285.0
HKD1_k127_4078274_6 Ion channel - - - 0.000000000000000000000000000000000000000000000003326 181.0
HKD1_k127_4078274_7 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000002175 168.0
HKD1_k127_4078274_8 alpha beta - - - 0.00000000000000000000006312 113.0
HKD1_k127_4083616_0 TIGRFAM ATP-dependent DNA helicase, RecQ family K03654 - 3.6.4.12 3.155e-269 841.0
HKD1_k127_4083616_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 7.7e-253 801.0
HKD1_k127_4083616_10 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 449.0
HKD1_k127_4083616_11 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 424.0
HKD1_k127_4083616_12 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 399.0
HKD1_k127_4083616_13 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 401.0
HKD1_k127_4083616_14 MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 400.0
HKD1_k127_4083616_15 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 339.0
HKD1_k127_4083616_16 cell redox homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 315.0
HKD1_k127_4083616_17 N-terminal domain of NWD NACHT-NTPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 300.0
HKD1_k127_4083616_18 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 267.0
HKD1_k127_4083616_19 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001724 268.0
HKD1_k127_4083616_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.92e-220 700.0
HKD1_k127_4083616_20 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000001227 228.0
HKD1_k127_4083616_21 Agenet domain - - - 0.00000000000000000000000000000000000000000000000000000000000002338 229.0
HKD1_k127_4083616_22 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000004757 211.0
HKD1_k127_4083616_23 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000007128 213.0
HKD1_k127_4083616_24 - - - - 0.00000000000000000000000000000000000000000000000000002787 192.0
HKD1_k127_4083616_25 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000001871 187.0
HKD1_k127_4083616_26 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000007866 164.0
HKD1_k127_4083616_27 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000002273 165.0
HKD1_k127_4083616_28 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000579 138.0
HKD1_k127_4083616_29 Glutamyl-tRNAGlu reductase, N-terminal domain K02492 - 1.2.1.70 0.0000000000000000000000000002787 125.0
HKD1_k127_4083616_3 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.378e-215 687.0
HKD1_k127_4083616_30 Response regulator, receiver K11443 - - 0.0000000000000000000000006354 110.0
HKD1_k127_4083616_31 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000007537 104.0
HKD1_k127_4083616_32 PFAM YcfA-like protein - - - 0.000000000000000000000001458 104.0
HKD1_k127_4083616_33 Transposase IS200 like - - - 0.00000000000002105 75.0
HKD1_k127_4083616_34 - - - - 0.0000000000001394 81.0
HKD1_k127_4083616_35 histidine kinase HAMP region domain protein K11527 - 2.7.13.3 0.000000003151 61.0
HKD1_k127_4083616_36 - - - - 0.000002841 50.0
HKD1_k127_4083616_38 Transposase K07491 - - 0.0002643 43.0
HKD1_k127_4083616_39 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0009762 49.0
HKD1_k127_4083616_4 HELICc2 K03722 - 3.6.4.12 1.931e-203 653.0
HKD1_k127_4083616_5 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 574.0
HKD1_k127_4083616_6 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 576.0
HKD1_k127_4083616_7 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 573.0
HKD1_k127_4083616_8 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 557.0
HKD1_k127_4083616_9 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 468.0
HKD1_k127_4090536_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 538.0
HKD1_k127_4090536_1 Bacterial capsule synthesis protein PGA_cap K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001316 288.0
HKD1_k127_4090536_2 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001292 266.0
HKD1_k127_4090536_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001673 273.0
HKD1_k127_4090536_4 ribose 5-phosphate isomerase B K00761,K01808 - 2.4.2.9,5.3.1.6 0.00000000000000000000000000000000000000008209 161.0
HKD1_k127_4090536_5 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000113 154.0
HKD1_k127_4090536_6 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000006686 133.0
HKD1_k127_4090536_7 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000000000000000003706 95.0
HKD1_k127_4090536_8 SnoaL-like polyketide cyclase K07255 - - 0.00002035 53.0
HKD1_k127_4096247_0 - - - - 0.0 1044.0
HKD1_k127_4096247_1 Sigma-54 interaction domain K15836 - - 7.025e-274 865.0
HKD1_k127_4096247_10 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 250.0
HKD1_k127_4096247_11 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001079 249.0
HKD1_k127_4096247_12 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000002425 219.0
HKD1_k127_4096247_13 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000001816 211.0
HKD1_k127_4096247_14 - - - - 0.000000000000000000000000000000000000000000000000002666 184.0
HKD1_k127_4096247_15 - - - - 0.00000000000000000000000000000000000000000000000007167 181.0
HKD1_k127_4096247_16 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000000000000000006849 178.0
HKD1_k127_4096247_17 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000002973 184.0
HKD1_k127_4096247_18 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K15580 - - 0.00000000000000000000000000000005117 147.0
HKD1_k127_4096247_19 - - - - 0.0000000000001014 78.0
HKD1_k127_4096247_2 - - - - 1.746e-266 863.0
HKD1_k127_4096247_20 - - - - 0.000000000009105 68.0
HKD1_k127_4096247_21 domain, Protein K01179,K01216,K03332,K20276 - 3.2.1.4,3.2.1.73,3.2.1.80 0.00000000005078 78.0
HKD1_k127_4096247_22 Glyoxalase-like domain K01759 - 4.4.1.5 0.000002216 54.0
HKD1_k127_4096247_23 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0001866 56.0
HKD1_k127_4096247_3 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 581.0
HKD1_k127_4096247_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 520.0
HKD1_k127_4096247_5 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 449.0
HKD1_k127_4096247_6 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 308.0
HKD1_k127_4096247_7 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 327.0
HKD1_k127_4096247_8 succinylglutamate desuccinylase activity K05526 - 3.5.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002988 285.0
HKD1_k127_4096247_9 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009783 272.0
HKD1_k127_4117471_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 530.0
HKD1_k127_4117471_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 466.0
HKD1_k127_4117471_2 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 357.0
HKD1_k127_4117471_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 297.0
HKD1_k127_4117471_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000003907 215.0
HKD1_k127_4117471_5 Histone deacetylation protein Rxt3 - - - 0.0000000000000000000000000000000000000000000000002345 188.0
HKD1_k127_4117471_6 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000001085 188.0
HKD1_k127_4117471_7 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000312 151.0
HKD1_k127_4117471_8 TIR domain - - - 0.000000000000000000000003444 113.0
HKD1_k127_4129280_0 WD-40 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 442.0
HKD1_k127_4129280_1 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000004682 86.0
HKD1_k127_4197370_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 629.0
HKD1_k127_4197370_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000001088 269.0
HKD1_k127_4197370_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000003283 227.0
HKD1_k127_4197370_3 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000001653 154.0
HKD1_k127_4197370_4 - - - - 0.0000009454 51.0
HKD1_k127_4197370_5 peptidylprolyl isomerase K03769,K07533 - 5.2.1.8 0.0003504 44.0
HKD1_k127_4238413_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 532.0
HKD1_k127_4238413_1 cobalamin-transporting ATPase activity K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 409.0
HKD1_k127_4238413_2 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000007074 176.0
HKD1_k127_4238413_3 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000004159 131.0
HKD1_k127_4238413_4 Domain of unknown function (DUF4383) - - - 0.000009455 53.0
HKD1_k127_4299683_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 550.0
HKD1_k127_4299683_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 551.0
HKD1_k127_4299683_2 Vault protein inter-alpha-trypsin domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 311.0
HKD1_k127_4299683_3 Belongs to the glycosyl hydrolase 28 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000191 281.0
HKD1_k127_4299683_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000839 222.0
HKD1_k127_4299683_5 Sugar transferase K19428 - - 0.0000000000000000000000000004113 128.0
HKD1_k127_4305417_0 Lantibiotic biosynthesis dehydratase C-term K20483 - - 1.282e-293 935.0
HKD1_k127_4305417_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 416.0
HKD1_k127_4305417_2 HlyD membrane-fusion protein of T1SS K02022,K11003 - - 0.0000000000002005 78.0
HKD1_k127_4327129_0 Sortilin, neurotensin receptor 3, - - - 0.0 1371.0
HKD1_k127_4327129_1 repeat protein - - - 5.32e-278 869.0
HKD1_k127_4327129_2 Belongs to the glycosyl hydrolase 28 family K15532 - 3.2.1.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007654 593.0
HKD1_k127_4327129_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 359.0
HKD1_k127_4327129_4 Ornithine cyclodeaminase/mu-crystallin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 292.0
HKD1_k127_4327129_5 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001428 250.0
HKD1_k127_4327129_6 Transposase IS200 like - - - 0.000000000000008662 78.0
HKD1_k127_437294_0 Cys/Met metabolism PLP-dependent enzyme K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 489.0
HKD1_k127_437294_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000004623 256.0
HKD1_k127_437294_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000005204 234.0
HKD1_k127_437294_3 TPR Domain containing protein K12600 - - 0.000000000000000000000000000000009601 141.0
HKD1_k127_437294_4 Regulatory protein - - - 0.0000000000000000000000001605 114.0
HKD1_k127_437294_5 chlorophyll binding K01186,K02487,K12543 - 3.2.1.18 0.00000000000133 79.0
HKD1_k127_4375318_0 Carboxypeptidase regulatory-like domain - - - 1.399e-277 894.0
HKD1_k127_4375318_1 ATPase activity K13527 - - 2.811e-228 737.0
HKD1_k127_4375318_10 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 297.0
HKD1_k127_4375318_11 PFAM WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008011 291.0
HKD1_k127_4375318_12 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000002249 268.0
HKD1_k127_4375318_13 TROVE domain K11127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005055 286.0
HKD1_k127_4375318_14 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000002997 259.0
HKD1_k127_4375318_15 ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000007306 267.0
HKD1_k127_4375318_16 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002954 253.0
HKD1_k127_4375318_17 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.00000000000000000000000000000000000000000000000000000000000000000005095 253.0
HKD1_k127_4375318_18 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000513 239.0
HKD1_k127_4375318_19 Pup-ligase protein K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.0000000000000000000000000000000000000000000000000000000000001918 231.0
HKD1_k127_4375318_2 efflux transmembrane transporter activity - - - 8.773e-216 697.0
HKD1_k127_4375318_20 WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000002448 238.0
HKD1_k127_4375318_21 peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000003152 231.0
HKD1_k127_4375318_22 NIPSNAP - - - 0.000000000000000000000000000000000000000000000000000001267 192.0
HKD1_k127_4375318_23 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K10941 - - 0.00000000000000000000000000000000000000000000000000004888 207.0
HKD1_k127_4375318_24 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000009136 183.0
HKD1_k127_4375318_25 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000002015 173.0
HKD1_k127_4375318_26 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 0.000000000000000000000000000000000000001102 151.0
HKD1_k127_4375318_27 Ankyrin repeat domain-containing protein 50-like K21440 - - 0.000000000000000000000000000000000000008095 165.0
HKD1_k127_4375318_28 Cupin domain - - - 0.00000000000000000000000000000000000002321 148.0
HKD1_k127_4375318_3 Beta-galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 618.0
HKD1_k127_4375318_30 PFAM Low molecular weight phosphotyrosine protein phosphatase - - - 0.0000000000000000000000000000000009087 134.0
HKD1_k127_4375318_31 DNA mediated transformation K04096 - - 0.00000000000000000000000000000003707 134.0
HKD1_k127_4375318_32 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000002565 133.0
HKD1_k127_4375318_33 - - - - 0.00000000000000000001284 95.0
HKD1_k127_4375318_34 - - - - 0.00000000000000000005189 91.0
HKD1_k127_4375318_35 OsmC-like protein - - - 0.0000000000000000007227 89.0
HKD1_k127_4375318_36 Belongs to the ClpA ClpB family K03696 - - 0.000000000000001209 89.0
HKD1_k127_4375318_37 PFAM Mov34 MPN PAD-1 family - - - 0.00000000005475 74.0
HKD1_k127_4375318_38 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000002799 64.0
HKD1_k127_4375318_39 protein kinase activity - - - 0.000000001571 71.0
HKD1_k127_4375318_4 WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 454.0
HKD1_k127_4375318_40 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000001718 57.0
HKD1_k127_4375318_42 Protein kinase domain K12132 - 2.7.11.1 0.000001268 55.0
HKD1_k127_4375318_43 Acetyltransferase - - - 0.000001271 57.0
HKD1_k127_4375318_44 Ubiquitin-conjugating enzyme E2, catalytic domain homologues - - - 0.000001295 59.0
HKD1_k127_4375318_45 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0008026 49.0
HKD1_k127_4375318_5 PFAM ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 399.0
HKD1_k127_4375318_6 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 377.0
HKD1_k127_4375318_7 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 383.0
HKD1_k127_4375318_8 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 355.0
HKD1_k127_4375318_9 NACHT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 319.0
HKD1_k127_4413371_0 MMPL family K03296 - - 0.0 1214.0
HKD1_k127_4413371_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1210.0
HKD1_k127_4413371_10 PFAM cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 465.0
HKD1_k127_4413371_11 cAMP biosynthetic process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 469.0
HKD1_k127_4413371_12 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 394.0
HKD1_k127_4413371_13 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 344.0
HKD1_k127_4413371_14 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 352.0
HKD1_k127_4413371_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 333.0
HKD1_k127_4413371_16 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 328.0
HKD1_k127_4413371_17 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 314.0
HKD1_k127_4413371_18 undecaprenyl-diphosphatase activity K06153 GO:0006950,GO:0008150,GO:0050896,GO:0051409 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000002852 267.0
HKD1_k127_4413371_19 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000003283 266.0
HKD1_k127_4413371_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1164.0
HKD1_k127_4413371_20 Glycosyl hydrolases family 25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004125 248.0
HKD1_k127_4413371_21 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000225 240.0
HKD1_k127_4413371_22 PFAM Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006404 241.0
HKD1_k127_4413371_23 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000001066 244.0
HKD1_k127_4413371_24 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000008115 220.0
HKD1_k127_4413371_25 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000772 220.0
HKD1_k127_4413371_26 -acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000004084 199.0
HKD1_k127_4413371_27 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000006619 206.0
HKD1_k127_4413371_28 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000002042 200.0
HKD1_k127_4413371_29 - - - - 0.000000000000000000000000000000000000000000000000001333 198.0
HKD1_k127_4413371_3 serine-type peptidase activity - - - 0.0 1069.0
HKD1_k127_4413371_30 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000006918 187.0
HKD1_k127_4413371_31 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K02528,K16924 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 0.000000000000000000000000000000000000000000000009556 183.0
HKD1_k127_4413371_32 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000005256 179.0
HKD1_k127_4413371_33 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000001837 172.0
HKD1_k127_4413371_34 Transcriptional repressor, CopY family - - - 0.000000000000000000000000000000000000000002274 158.0
HKD1_k127_4413371_35 lipopolysaccharide transport K09774 - - 0.000000000000000000000000000000000000000003136 178.0
HKD1_k127_4413371_36 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000004854 157.0
HKD1_k127_4413371_37 CHAT domain - - - 0.0000000000000000000000000000000000000001316 174.0
HKD1_k127_4413371_38 Phosphate acyltransferases K15781 - 2.3.1.51,3.1.3.3 0.00000000000000000000000000000000000006257 154.0
HKD1_k127_4413371_39 - - - - 0.00000000000000000000000000000000002572 156.0
HKD1_k127_4413371_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 571.0
HKD1_k127_4413371_40 Yqey-like protein K09117 - - 0.000000000000000000000000000000007099 132.0
HKD1_k127_4413371_41 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000000001929 139.0
HKD1_k127_4413371_42 ECF sigma factor K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000191 126.0
HKD1_k127_4413371_43 Protein conserved in bacteria - - - 0.00000000000000000000000009389 110.0
HKD1_k127_4413371_44 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000159 106.0
HKD1_k127_4413371_45 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000769 100.0
HKD1_k127_4413371_46 Glutathione peroxidase - - - 0.000000000000001853 91.0
HKD1_k127_4413371_47 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000261 74.0
HKD1_k127_4413371_48 - - - - 0.00001963 47.0
HKD1_k127_4413371_49 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00004989 57.0
HKD1_k127_4413371_5 PFAM Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 575.0
HKD1_k127_4413371_50 Proline-rich acidic protein 1 K21250 GO:0000981,GO:0003674,GO:0003700,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.0004293 46.0
HKD1_k127_4413371_51 von Willebrand factor type A domain K07114 - - 0.0007549 52.0
HKD1_k127_4413371_6 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 507.0
HKD1_k127_4413371_7 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 506.0
HKD1_k127_4413371_8 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 480.0
HKD1_k127_4413371_9 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 475.0
HKD1_k127_4428545_0 transport - - - 0.0 1084.0
HKD1_k127_4428545_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1047.0
HKD1_k127_4428545_10 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 434.0
HKD1_k127_4428545_11 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 454.0
HKD1_k127_4428545_12 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 413.0
HKD1_k127_4428545_13 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 410.0
HKD1_k127_4428545_14 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 377.0
HKD1_k127_4428545_15 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 391.0
HKD1_k127_4428545_16 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 360.0
HKD1_k127_4428545_17 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 355.0
HKD1_k127_4428545_18 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 355.0
HKD1_k127_4428545_19 PFAM Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 340.0
HKD1_k127_4428545_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.301e-308 953.0
HKD1_k127_4428545_20 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 339.0
HKD1_k127_4428545_21 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 326.0
HKD1_k127_4428545_22 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 328.0
HKD1_k127_4428545_23 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 316.0
HKD1_k127_4428545_24 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 296.0
HKD1_k127_4428545_25 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008081 265.0
HKD1_k127_4428545_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001208 269.0
HKD1_k127_4428545_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008737 269.0
HKD1_k127_4428545_28 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004521 257.0
HKD1_k127_4428545_29 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002734 249.0
HKD1_k127_4428545_3 cell adhesion involved in biofilm formation K13735,K20276 - - 1.183e-211 703.0
HKD1_k127_4428545_30 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000005157 234.0
HKD1_k127_4428545_31 helix_turn_helix gluconate operon transcriptional repressor K07978 - - 0.000000000000000000000000000000000000000000000000000000000000000008514 235.0
HKD1_k127_4428545_32 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000002095 224.0
HKD1_k127_4428545_33 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000007899 186.0
HKD1_k127_4428545_34 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000002465 196.0
HKD1_k127_4428545_35 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000008904 201.0
HKD1_k127_4428545_36 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000001229 193.0
HKD1_k127_4428545_37 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000003204 178.0
HKD1_k127_4428545_38 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000003716 180.0
HKD1_k127_4428545_39 methyltransferase - - - 0.0000000000000000000000000000000000000000000004584 173.0
HKD1_k127_4428545_4 Sodium:sulfate symporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 561.0
HKD1_k127_4428545_40 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000003455 184.0
HKD1_k127_4428545_41 AI-2E family transporter - - - 0.00000000000000000000000000000000001955 151.0
HKD1_k127_4428545_42 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000000003213 132.0
HKD1_k127_4428545_43 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000001295 134.0
HKD1_k127_4428545_44 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0042157,GO:0042158,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0097304,GO:0140096,GO:1901564,GO:1901566,GO:1901576 3.4.23.36 0.0000000000000000000000000000008624 128.0
HKD1_k127_4428545_45 lactoylglutathione lyase activity - - - 0.00000000000000000000000000001661 123.0
HKD1_k127_4428545_46 Glutathione peroxidase K02199 - - 0.0000000000000000000000000009318 119.0
HKD1_k127_4428545_47 - - - - 0.000000000000000000000000003119 126.0
HKD1_k127_4428545_48 Phospholipid methyltransferase - - - 0.0000000000000000000000000277 115.0
HKD1_k127_4428545_49 - - - - 0.0000000000000000000000002129 115.0
HKD1_k127_4428545_5 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 498.0
HKD1_k127_4428545_50 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000004801 110.0
HKD1_k127_4428545_51 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000124 114.0
HKD1_k127_4428545_53 Domain of unknown function (DUF4112) - - - 0.00000000000000000009757 96.0
HKD1_k127_4428545_54 DoxX K15977 - - 0.0000000000000000005458 93.0
HKD1_k127_4428545_55 Polymer-forming cytoskeletal - - - 0.000000000000000007843 91.0
HKD1_k127_4428545_56 - - - - 0.00000000000000001098 91.0
HKD1_k127_4428545_57 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.0000000000000000634 82.0
HKD1_k127_4428545_59 phosphorelay signal transduction system K03413 - - 0.0000000000000008089 83.0
HKD1_k127_4428545_6 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 497.0
HKD1_k127_4428545_60 Domain of unknown function (DUF4129) - - - 0.000000000000257 81.0
HKD1_k127_4428545_61 GyrI-like small molecule binding domain - - - 0.000000000002134 75.0
HKD1_k127_4428545_63 pathogenesis - - - 0.0000000000543 74.0
HKD1_k127_4428545_64 peptidyl-tyrosine sulfation - - - 0.0000000003937 71.0
HKD1_k127_4428545_65 repeat-containing protein - - - 0.00000001007 66.0
HKD1_k127_4428545_66 gas vesicle protein - - - 0.00000005132 61.0
HKD1_k127_4428545_67 Tetratricopeptide TPR_2 repeat protein - - - 0.00000005348 64.0
HKD1_k127_4428545_68 Domain of unknown function (DUF4350) - - - 0.00000009085 64.0
HKD1_k127_4428545_69 von Willebrand factor (vWF) type A domain K07114 - - 0.0000001192 57.0
HKD1_k127_4428545_7 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 459.0
HKD1_k127_4428545_71 Carboxypeptidase regulatory-like domain - - - 0.00001893 50.0
HKD1_k127_4428545_8 Amidohydrolase family K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 456.0
HKD1_k127_4428545_9 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 443.0
HKD1_k127_4482187_0 Protein of unknown function, DUF255 K06888 - - 1.809e-237 752.0
HKD1_k127_4482187_1 PFAM peptidase M13 K01415 - 3.4.24.71 3.017e-214 685.0
HKD1_k127_4482187_10 ATPases associated with a variety of cellular activities K10823,K10824 - 3.6.3.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 451.0
HKD1_k127_4482187_11 amino acid peptide transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 454.0
HKD1_k127_4482187_12 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 455.0
HKD1_k127_4482187_13 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 428.0
HKD1_k127_4482187_14 pectate lyase K01728 - 4.2.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 423.0
HKD1_k127_4482187_15 Belongs to the ABC transporter superfamily K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 413.0
HKD1_k127_4482187_16 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 434.0
HKD1_k127_4482187_17 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 410.0
HKD1_k127_4482187_18 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 406.0
HKD1_k127_4482187_19 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 392.0
HKD1_k127_4482187_2 Prolyl oligopeptidase family - - - 2.874e-197 635.0
HKD1_k127_4482187_20 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 397.0
HKD1_k127_4482187_21 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 394.0
HKD1_k127_4482187_22 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 370.0
HKD1_k127_4482187_23 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 361.0
HKD1_k127_4482187_24 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 358.0
HKD1_k127_4482187_25 'ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 354.0
HKD1_k127_4482187_26 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 350.0
HKD1_k127_4482187_27 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 346.0
HKD1_k127_4482187_28 PFAM Binding-protein-dependent transport system inner membrane component K02033,K15581,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 318.0
HKD1_k127_4482187_29 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 331.0
HKD1_k127_4482187_3 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 3.262e-195 624.0
HKD1_k127_4482187_30 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 304.0
HKD1_k127_4482187_31 Amino acid transporter K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 296.0
HKD1_k127_4482187_32 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003376 285.0
HKD1_k127_4482187_33 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000759 269.0
HKD1_k127_4482187_34 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002436 270.0
HKD1_k127_4482187_35 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003071 269.0
HKD1_k127_4482187_36 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008276 270.0
HKD1_k127_4482187_37 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004982 272.0
HKD1_k127_4482187_38 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000003721 240.0
HKD1_k127_4482187_39 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000001423 248.0
HKD1_k127_4482187_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 622.0
HKD1_k127_4482187_40 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000002606 226.0
HKD1_k127_4482187_41 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000001573 225.0
HKD1_k127_4482187_42 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000000000004007 220.0
HKD1_k127_4482187_43 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000000000000000000000000003281 231.0
HKD1_k127_4482187_44 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000003816 235.0
HKD1_k127_4482187_45 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000002023 215.0
HKD1_k127_4482187_46 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000004176 218.0
HKD1_k127_4482187_48 HD domain - - - 0.0000000000000000000000000000000000000000000000000000001329 212.0
HKD1_k127_4482187_49 response regulator receiver K02483,K07658 - - 0.000000000000000000000000000000000000000000000000000003427 202.0
HKD1_k127_4482187_5 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 610.0
HKD1_k127_4482187_50 - K00003,K00058,K01754,K04517,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,1.3.1.12,4.3.1.19 0.00000000000000000000000000000000000000000000000000001188 191.0
HKD1_k127_4482187_51 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000247 197.0
HKD1_k127_4482187_52 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000083 196.0
HKD1_k127_4482187_53 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.000000000000000000000000000000000000000000000002889 177.0
HKD1_k127_4482187_54 - - - - 0.000000000000000000000000000000000000000000000006183 181.0
HKD1_k127_4482187_55 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000005448 174.0
HKD1_k127_4482187_56 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000002291 173.0
HKD1_k127_4482187_57 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000005723 173.0
HKD1_k127_4482187_58 Penicillin-binding Protein K05364 - - 0.0000000000000000000000000000000000000001661 170.0
HKD1_k127_4482187_59 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000006594 158.0
HKD1_k127_4482187_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 567.0
HKD1_k127_4482187_60 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000006835 153.0
HKD1_k127_4482187_61 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000000005544 149.0
HKD1_k127_4482187_62 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.0000000000000000000000000000000000001878 160.0
HKD1_k127_4482187_63 EamA-like transporter family - - - 0.000000000000000000000000000000000002063 150.0
HKD1_k127_4482187_64 Transposase K07491 - - 0.00000000000000000000000000000000002143 140.0
HKD1_k127_4482187_65 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000255 143.0
HKD1_k127_4482187_66 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000008863 126.0
HKD1_k127_4482187_67 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000001551 128.0
HKD1_k127_4482187_68 COG2931, RTX toxins and related Ca2 -binding proteins K20276 - - 0.000000000000000000000000003958 127.0
HKD1_k127_4482187_69 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000002303 109.0
HKD1_k127_4482187_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 505.0
HKD1_k127_4482187_70 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000003481 103.0
HKD1_k127_4482187_71 DinB family - - - 0.000000000000000000002875 100.0
HKD1_k127_4482187_72 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000001072 94.0
HKD1_k127_4482187_74 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000227 84.0
HKD1_k127_4482187_76 Zinc metalloprotease (Elastase) - - - 0.000000000000436 84.0
HKD1_k127_4482187_77 antisigma factor binding - - - 0.0000000000007173 75.0
HKD1_k127_4482187_78 peptidase K01415,K07386 - 3.4.24.71 0.00000000004536 63.0
HKD1_k127_4482187_79 Forkhead associated domain - - - 0.00000004911 63.0
HKD1_k127_4482187_8 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 467.0
HKD1_k127_4482187_80 Tetratricopeptide repeat - - - 0.00000121 56.0
HKD1_k127_4482187_82 Tetratricopeptide repeat - - - 0.000006343 58.0
HKD1_k127_4482187_83 PFAM Protein kinase domain K07114 - - 0.0000111 56.0
HKD1_k127_4482187_84 - - - - 0.0000126 52.0
HKD1_k127_4482187_85 Endonuclease/Exonuclease/phosphatase family - - - 0.00003285 55.0
HKD1_k127_4482187_87 amino acid activation for nonribosomal peptide biosynthetic process K01113 - 3.1.3.1 0.0001824 54.0
HKD1_k127_4482187_88 23S rRNA-intervening sequence protein - - - 0.0002127 46.0
HKD1_k127_4482187_89 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0002916 46.0
HKD1_k127_4482187_9 ABC transporter K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 477.0
HKD1_k127_4482187_90 domain-containing protein K11674 GO:0000123,GO:0000228,GO:0000785,GO:0000790,GO:0002151,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0005783,GO:0005844,GO:0006325,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010521,GO:0010556,GO:0010558,GO:0010605,GO:0010639,GO:0012505,GO:0016043,GO:0016569,GO:0016570,GO:0016573,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019222,GO:0019538,GO:0030234,GO:0030425,GO:0031011,GO:0031248,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032204,GO:0032205,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033044,GO:0033202,GO:0034046,GO:0034708,GO:0035097,GO:0036211,GO:0036477,GO:0042995,GO:0043005,GO:0043025,GO:0043086,GO:0043170,GO:0043204,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043543,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044463,GO:0044464,GO:0044665,GO:0045934,GO:0048518,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051052,GO:0051053,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051276,GO:0051338,GO:0051348,GO:0051972,GO:0051974,GO:0060255,GO:0060341,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070603,GO:0070717,GO:0071339,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0097346,GO:0097447,GO:0097458,GO:0098772,GO:0120025,GO:0120038,GO:1900180,GO:1900182,GO:1901363,GO:1901564,GO:1902493,GO:1902494,GO:1903827,GO:1903829,GO:1904356,GO:1904357,GO:1904749,GO:1904751,GO:1904949,GO:1990234,GO:1990904,GO:2000112,GO:2000113,GO:2000278,GO:2000279,GO:2001251 - 0.0003805 51.0
HKD1_k127_4484073_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1395.0
HKD1_k127_4484073_1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1394.0
HKD1_k127_4484073_10 Fumarase C C-terminus - - - 1.265e-253 789.0
HKD1_k127_4484073_100 VIT family - - - 0.000000000000000000000000000000000000000186 158.0
HKD1_k127_4484073_101 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000002197 158.0
HKD1_k127_4484073_102 MerR, DNA binding - - - 0.000000000000000000000000000000000000004134 152.0
HKD1_k127_4484073_103 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000004718 154.0
HKD1_k127_4484073_104 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000005996 170.0
HKD1_k127_4484073_105 Haem-binding domain - - - 0.0000000000000000000000000000000000001084 147.0
HKD1_k127_4484073_106 Belongs to the TPP enzyme family K01637 - 4.1.3.1 0.000000000000000000000000000000000003482 157.0
HKD1_k127_4484073_107 cell redox homeostasis K01829,K03671 - 5.3.4.1 0.0000000000000000000000000000000002615 139.0
HKD1_k127_4484073_108 PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin - - - 0.000000000000000000000000000000002043 141.0
HKD1_k127_4484073_109 Protein of unknown function (DUF2490) - - - 0.00000000000000000000000000000001285 137.0
HKD1_k127_4484073_11 serine dehydratase beta chain K01752 - 4.3.1.17 3.37e-252 788.0
HKD1_k127_4484073_110 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000001591 148.0
HKD1_k127_4484073_111 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000502 130.0
HKD1_k127_4484073_112 response regulator K02282 - - 0.0000000000000000000000000000006591 127.0
HKD1_k127_4484073_113 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000006968 136.0
HKD1_k127_4484073_114 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000000000005242 120.0
HKD1_k127_4484073_115 Pfam Response regulator receiver - - - 0.0000000000000000000000000006901 119.0
HKD1_k127_4484073_116 RF-1 domain - - - 0.000000000000000000000000004171 114.0
HKD1_k127_4484073_117 phosphorelay signal transduction system K14987 - - 0.000000000000000000000000004645 115.0
HKD1_k127_4484073_118 Ion channel - - - 0.000000000000000000000000005366 116.0
HKD1_k127_4484073_119 domain, Protein - - - 0.0000000000000000000000006434 122.0
HKD1_k127_4484073_12 Sulfate permease family - - - 9.557e-236 743.0
HKD1_k127_4484073_120 Sulfatase K01130 - 3.1.6.1 0.000000000000000000002528 94.0
HKD1_k127_4484073_121 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000006397 98.0
HKD1_k127_4484073_122 Protein of unknown function (DUF2892) - - - 0.000000000000000000009566 95.0
HKD1_k127_4484073_123 - - - - 0.0000000000000000000839 96.0
HKD1_k127_4484073_124 - - - - 0.0000000000000000001672 91.0
HKD1_k127_4484073_125 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000138 91.0
HKD1_k127_4484073_126 Protein of unknown function (DUF2490) - - - 0.00000000000000008612 89.0
HKD1_k127_4484073_127 Domain of unknown function DUF11 - - - 0.0000000000000001727 95.0
HKD1_k127_4484073_128 Domain of unknown function (DUF4136) - - - 0.00000000000001648 81.0
HKD1_k127_4484073_129 - - - - 0.00000000000003396 79.0
HKD1_k127_4484073_13 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 1.033e-214 678.0
HKD1_k127_4484073_130 Terminase RNaseH-like domain - - - 0.00000000000004385 73.0
HKD1_k127_4484073_131 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000003039 74.0
HKD1_k127_4484073_132 Periplasmic or secreted lipoprotein - - - 0.0000000000003049 78.0
HKD1_k127_4484073_133 domain, Protein K01406,K01448,K13735,K20276,K21449 - 3.4.24.40,3.5.1.28 0.000000000196 74.0
HKD1_k127_4484073_134 Belongs to the 'phage' integrase family - - - 0.0000000002612 64.0
HKD1_k127_4484073_135 long-chain fatty acid transport protein - - - 0.000000001744 68.0
HKD1_k127_4484073_136 Histidine kinase - - - 0.00000001133 61.0
HKD1_k127_4484073_137 PFAM Protein kinase domain K08884 - 2.7.11.1 0.000000042 63.0
HKD1_k127_4484073_138 BlaR1 peptidase M56 - - - 0.000000127 64.0
HKD1_k127_4484073_139 Prokaryotic N-terminal methylation motif K02456,K02650 - - 0.0000002132 59.0
HKD1_k127_4484073_14 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 6.897e-212 678.0
HKD1_k127_4484073_140 Belongs to the ATP-dependent AMP-binding enzyme family K12436,K13611 - - 0.000001272 62.0
HKD1_k127_4484073_141 - - - - 0.000002522 55.0
HKD1_k127_4484073_142 Belongs to the 'phage' integrase family - - - 0.00000261 58.0
HKD1_k127_4484073_143 Antibiotic biosynthesis monooxygenase - GO:0003674,GO:0003824 - 0.000002905 53.0
HKD1_k127_4484073_144 - - - - 0.00001929 46.0
HKD1_k127_4484073_146 Sulfate permease family - - - 0.0001032 45.0
HKD1_k127_4484073_147 repeat-containing protein K22221 - - 0.0001283 55.0
HKD1_k127_4484073_148 - - - - 0.0001297 53.0
HKD1_k127_4484073_149 acr, cog1565 - - - 0.0001452 49.0
HKD1_k127_4484073_15 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 5.343e-201 633.0
HKD1_k127_4484073_150 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0002171 48.0
HKD1_k127_4484073_151 BTB And C-terminal Kelch K10446 GO:0000151,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0014069,GO:0016567,GO:0019538,GO:0019941,GO:0030163,GO:0031461,GO:0031463,GO:0031974,GO:0031981,GO:0032279,GO:0032446,GO:0032991,GO:0036211,GO:0036477,GO:0042995,GO:0043005,GO:0043025,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044456,GO:0044464,GO:0045202,GO:0051603,GO:0070013,GO:0070647,GO:0071704,GO:0097458,GO:0098794,GO:0098984,GO:0099572,GO:0120025,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234 - 0.0002584 55.0
HKD1_k127_4484073_152 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0009153 44.0
HKD1_k127_4484073_16 Tfp pilus assembly protein FimV - - - 9.321e-201 640.0
HKD1_k127_4484073_17 PFAM RNA polymerase sigma-70 region 2 K03088 - - 6.267e-194 612.0
HKD1_k127_4484073_18 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 612.0
HKD1_k127_4484073_19 cystathionine gamma-synthase activity K01739,K01740,K01760,K01761 - 2.5.1.48,2.5.1.49,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 584.0
HKD1_k127_4484073_2 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1375.0
HKD1_k127_4484073_20 Phospholipase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 544.0
HKD1_k127_4484073_21 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 529.0
HKD1_k127_4484073_22 Asparaginase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 526.0
HKD1_k127_4484073_23 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 525.0
HKD1_k127_4484073_24 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 512.0
HKD1_k127_4484073_25 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 507.0
HKD1_k127_4484073_26 aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 505.0
HKD1_k127_4484073_27 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 484.0
HKD1_k127_4484073_28 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 467.0
HKD1_k127_4484073_29 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 460.0
HKD1_k127_4484073_3 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1299.0
HKD1_k127_4484073_30 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 457.0
HKD1_k127_4484073_31 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 459.0
HKD1_k127_4484073_32 PFAM ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 447.0
HKD1_k127_4484073_33 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 422.0
HKD1_k127_4484073_34 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 433.0
HKD1_k127_4484073_35 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 419.0
HKD1_k127_4484073_36 transcription factor binding K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 445.0
HKD1_k127_4484073_37 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 412.0
HKD1_k127_4484073_38 anaerobic c4-dicarboxylate K07791,K07792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 407.0
HKD1_k127_4484073_39 Sodium calcium exchanger membrane K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 399.0
HKD1_k127_4484073_4 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 0.0 1269.0
HKD1_k127_4484073_40 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 391.0
HKD1_k127_4484073_41 Transcriptional regulator K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 402.0
HKD1_k127_4484073_42 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 383.0
HKD1_k127_4484073_43 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 382.0
HKD1_k127_4484073_44 Pseudouridylate K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 351.0
HKD1_k127_4484073_45 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 331.0
HKD1_k127_4484073_46 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 327.0
HKD1_k127_4484073_47 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 343.0
HKD1_k127_4484073_48 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 318.0
HKD1_k127_4484073_49 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 321.0
HKD1_k127_4484073_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1244.0
HKD1_k127_4484073_50 Possible lysine decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 302.0
HKD1_k127_4484073_51 Transcriptional regulator K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 322.0
HKD1_k127_4484073_52 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 304.0
HKD1_k127_4484073_53 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 300.0
HKD1_k127_4484073_54 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 297.0
HKD1_k127_4484073_55 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001449 279.0
HKD1_k127_4484073_56 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001292 273.0
HKD1_k127_4484073_57 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005212 269.0
HKD1_k127_4484073_58 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001203 259.0
HKD1_k127_4484073_59 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001699 255.0
HKD1_k127_4484073_6 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 6.008e-276 863.0
HKD1_k127_4484073_60 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002411 246.0
HKD1_k127_4484073_61 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002605 244.0
HKD1_k127_4484073_62 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000053 240.0
HKD1_k127_4484073_63 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000005349 241.0
HKD1_k127_4484073_64 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000001005 233.0
HKD1_k127_4484073_65 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000001682 232.0
HKD1_k127_4484073_66 Autotransporter beta-domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002503 253.0
HKD1_k127_4484073_67 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000616 236.0
HKD1_k127_4484073_68 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000001154 228.0
HKD1_k127_4484073_69 response regulator receiver K13041 - - 0.00000000000000000000000000000000000000000000000000000000000005077 221.0
HKD1_k127_4484073_7 Carboxypeptidase regulatory-like domain - - - 3.481e-261 839.0
HKD1_k127_4484073_70 - - - - 0.0000000000000000000000000000000000000000000000000000000000002946 222.0
HKD1_k127_4484073_71 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000003422 222.0
HKD1_k127_4484073_72 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000001614 224.0
HKD1_k127_4484073_73 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000002464 206.0
HKD1_k127_4484073_74 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000004461 226.0
HKD1_k127_4484073_75 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000004709 214.0
HKD1_k127_4484073_76 - - - - 0.00000000000000000000000000000000000000000000000000000000004719 213.0
HKD1_k127_4484073_77 Belongs to the glycosyl hydrolase 43 family - - - 0.00000000000000000000000000000000000000000000000000000000009234 226.0
HKD1_k127_4484073_78 Transposase K07491 - - 0.000000000000000000000000000000000000000000000000000000005875 201.0
HKD1_k127_4484073_79 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000003949 210.0
HKD1_k127_4484073_8 Sulfatase K01130 - 3.1.6.1 2.743e-258 815.0
HKD1_k127_4484073_80 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000002217 199.0
HKD1_k127_4484073_81 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000009558 195.0
HKD1_k127_4484073_82 TIGRFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000002081 198.0
HKD1_k127_4484073_83 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000003893 194.0
HKD1_k127_4484073_84 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000004186 205.0
HKD1_k127_4484073_85 cytochrome - - - 0.00000000000000000000000000000000000000000000000000004971 194.0
HKD1_k127_4484073_86 alpha-ribazole phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000004191 190.0
HKD1_k127_4484073_88 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000000000000000000000000000825 186.0
HKD1_k127_4484073_89 - - - - 0.000000000000000000000000000000000000000000000000414 185.0
HKD1_k127_4484073_9 Arylsulfatase K01130 - 3.1.6.1 3.808e-256 797.0
HKD1_k127_4484073_90 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000000000000002799 201.0
HKD1_k127_4484073_91 TIGRFAM molybdenum cofactor synthesis - - - 0.000000000000000000000000000000000000000000001426 171.0
HKD1_k127_4484073_92 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000002208 171.0
HKD1_k127_4484073_93 - - - - 0.0000000000000000000000000000000000000000000309 169.0
HKD1_k127_4484073_94 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000646 163.0
HKD1_k127_4484073_95 - - - - 0.0000000000000000000000000000000000000000001154 162.0
HKD1_k127_4484073_96 - - - - 0.000000000000000000000000000000000000000002609 158.0
HKD1_k127_4484073_97 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000055 164.0
HKD1_k127_4484073_98 Rossmann-like domain - - - 0.000000000000000000000000000000000000000007904 168.0
HKD1_k127_4484073_99 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000001493 161.0
HKD1_k127_4502552_0 cellulose binding - - - 0.0 1364.0
HKD1_k127_4502552_1 Amino acid permease - - - 3.833e-214 682.0
HKD1_k127_4502552_10 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000007779 157.0
HKD1_k127_4502552_11 - - - - 0.00000000000000000000000000001119 123.0
HKD1_k127_4502552_12 RNA recognition motif - - - 0.00000000000000000000000000004411 118.0
HKD1_k127_4502552_13 Probable zinc-ribbon domain - - - 0.0000000000000000000000000001302 119.0
HKD1_k127_4502552_14 - - - - 0.0000000000000000000000000008992 117.0
HKD1_k127_4502552_15 - - - - 0.00000000000000000006228 100.0
HKD1_k127_4502552_16 COG0666 FOG Ankyrin repeat K06867 - - 0.00000000000000001036 96.0
HKD1_k127_4502552_17 Transposase IS200 like - - - 0.0000000000000009663 79.0
HKD1_k127_4502552_18 - - - - 0.000000000009485 69.0
HKD1_k127_4502552_19 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000401 68.0
HKD1_k127_4502552_2 beta-galactosidase activity - - - 5.23e-200 631.0
HKD1_k127_4502552_20 DnaJ molecular chaperone homology domain K03686,K05516 - - 0.0000000003843 68.0
HKD1_k127_4502552_21 - - - - 0.00000002594 57.0
HKD1_k127_4502552_22 Transposase IS200 like - - - 0.00005188 48.0
HKD1_k127_4502552_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 475.0
HKD1_k127_4502552_4 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 399.0
HKD1_k127_4502552_5 PFAM Peptidase M1 membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 334.0
HKD1_k127_4502552_6 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000005919 207.0
HKD1_k127_4502552_7 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986,K15342 - 2.7.7.49 0.00000000000000000000000000000000000000000000000004984 181.0
HKD1_k127_4502552_8 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000000000004773 179.0
HKD1_k127_4502552_9 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000000002817 185.0
HKD1_k127_4527045_0 glycoside hydrolase family 38 K01191 - 3.2.1.24 0.0 1464.0
HKD1_k127_4527045_1 Glycosyl hydrolase family 3 K05349 - 3.2.1.21 7.07e-322 1004.0
HKD1_k127_4527045_2 Right handed beta helix region - - - 1.113e-196 629.0
HKD1_k127_4527045_3 Alginate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 355.0
HKD1_k127_4570325_0 Sulfatase K01130 - 3.1.6.1 4.365e-280 884.0
HKD1_k127_4570325_1 NMT1/THI5 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 474.0
HKD1_k127_4570325_10 CAAX protease self-immunity K07052 - - 0.0000000000000000000000001509 107.0
HKD1_k127_4570325_11 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000001419 70.0
HKD1_k127_4570325_12 protease - - - 0.00000002956 66.0
HKD1_k127_4570325_13 - - - - 0.0000003448 64.0
HKD1_k127_4570325_14 gag-polyprotein putative aspartyl protease - - - 0.0001287 54.0
HKD1_k127_4570325_2 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 432.0
HKD1_k127_4570325_3 ATPases associated with a variety of cellular activities K15555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 378.0
HKD1_k127_4570325_4 PFAM Amino acid K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 326.0
HKD1_k127_4570325_5 - - - - 0.000000000000000000000000000000000000000000000000000000000001344 213.0
HKD1_k127_4570325_6 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000007637 208.0
HKD1_k127_4570325_7 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000000002411 187.0
HKD1_k127_4570325_8 Transcriptional regulator K11921,K19338 - - 0.0000000000000000000000000000000000000000000000005233 188.0
HKD1_k127_4570325_9 - - - - 0.0000000000000000000000000000000000000000000000773 173.0
HKD1_k127_4593831_0 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 462.0
HKD1_k127_4593831_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 420.0
HKD1_k127_4593831_2 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000000004158 150.0
HKD1_k127_4593831_3 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000002363 138.0
HKD1_k127_4593831_4 Glyoxalase-like domain - - - 0.00000000000000000000009878 102.0
HKD1_k127_4593831_5 - - - - 0.0000000000000002405 88.0
HKD1_k127_4599029_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.917e-305 977.0
HKD1_k127_4599029_1 C-terminus of AA_permease K03294 - - 3.489e-221 697.0
HKD1_k127_4599029_10 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 310.0
HKD1_k127_4599029_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004286 302.0
HKD1_k127_4599029_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001836 297.0
HKD1_k127_4599029_13 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000349 275.0
HKD1_k127_4599029_14 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003168 271.0
HKD1_k127_4599029_15 eight transmembrane protein EpsH - - - 0.00000000000000000000000000000000000000000000000000000000000000003436 237.0
HKD1_k127_4599029_16 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001513 235.0
HKD1_k127_4599029_17 AAA domain K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000005829 231.0
HKD1_k127_4599029_18 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000001663 184.0
HKD1_k127_4599029_19 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000006962 194.0
HKD1_k127_4599029_2 Beta-lactamase - - - 4.148e-195 630.0
HKD1_k127_4599029_20 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000539 177.0
HKD1_k127_4599029_21 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000006124 173.0
HKD1_k127_4599029_22 Lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000004803 173.0
HKD1_k127_4599029_23 Chain length determinant protein - - - 0.00000000000000000000000000000000000000001488 173.0
HKD1_k127_4599029_24 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.00000000000000000000000000000000000001183 158.0
HKD1_k127_4599029_25 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.0000000000000000000000000000000000001475 155.0
HKD1_k127_4599029_26 - - - - 0.000000000000000000000000000000000002203 160.0
HKD1_k127_4599029_27 ATP hydrolysis coupled proton transport K02123 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000002611 140.0
HKD1_k127_4599029_28 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000001682 141.0
HKD1_k127_4599029_29 Protein of unknown function (DUF1232) - - - 0.00000000000000000000001583 107.0
HKD1_k127_4599029_3 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009521 600.0
HKD1_k127_4599029_30 regulation of response to stimulus - - - 0.0000000000000000000001224 109.0
HKD1_k127_4599029_31 RNA-binding S4 domain protein - - - 0.0000000000000001156 85.0
HKD1_k127_4599029_32 Uncharacterised ACR (DUF711) K09157 - - 0.000000000000001395 78.0
HKD1_k127_4599029_33 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000003137 83.0
HKD1_k127_4599029_34 polysaccharide export protein K01991 - - 0.0000000000003364 80.0
HKD1_k127_4599029_35 von Willebrand factor, type A - - - 0.000000000001429 79.0
HKD1_k127_4599029_36 Alpha-amylase domain K01182 - 3.2.1.10 0.000000000001654 78.0
HKD1_k127_4599029_37 Alpha-L-rhamnosidase - - - 0.00000000005754 76.0
HKD1_k127_4599029_38 Domain of unknown function (DUF4440) - - - 0.000000001348 65.0
HKD1_k127_4599029_39 L,D-transpeptidase catalytic domain - - - 0.000000003174 69.0
HKD1_k127_4599029_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 477.0
HKD1_k127_4599029_40 Glycosyl transferase family 41 - - - 0.000000004375 69.0
HKD1_k127_4599029_41 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000001093 69.0
HKD1_k127_4599029_42 protein related to plant photosystem II stability assembly factor - - - 0.000006187 53.0
HKD1_k127_4599029_43 - - - - 0.00003883 53.0
HKD1_k127_4599029_5 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 431.0
HKD1_k127_4599029_6 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 394.0
HKD1_k127_4599029_7 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 374.0
HKD1_k127_4599029_8 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 356.0
HKD1_k127_4599029_9 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 310.0
HKD1_k127_4698315_0 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 6.906e-258 818.0
HKD1_k127_4698315_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 586.0
HKD1_k127_4698315_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 511.0
HKD1_k127_4698315_3 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 430.0
HKD1_k127_4698315_4 Beta-lactamase class C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 344.0
HKD1_k127_4698315_5 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001771 280.0
HKD1_k127_4698315_6 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000000000000000000002041 209.0
HKD1_k127_4698315_7 DEK C terminal domain - - - 0.000000000000000007854 96.0
HKD1_k127_4698315_8 Pkd domain containing protein - - - 0.0000000005706 65.0
HKD1_k127_4782081_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.242e-230 723.0
HKD1_k127_4782081_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 531.0
HKD1_k127_4782081_10 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004648 277.0
HKD1_k127_4782081_11 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000007704 218.0
HKD1_k127_4782081_12 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000001693 190.0
HKD1_k127_4782081_13 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000002031 197.0
HKD1_k127_4782081_14 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.000000000000000000000000000000000000000003671 163.0
HKD1_k127_4782081_15 Transposase K07491 - - 0.00000000000000000000000000000001076 131.0
HKD1_k127_4782081_16 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.00000000000000000000002396 113.0
HKD1_k127_4782081_17 Universal stress protein - - - 0.0000000000000000000001663 103.0
HKD1_k127_4782081_18 NUDIX domain - - - 0.000000000000000002903 91.0
HKD1_k127_4782081_19 - - - - 0.000000000000007401 79.0
HKD1_k127_4782081_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 518.0
HKD1_k127_4782081_20 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000006541 62.0
HKD1_k127_4782081_21 domain protein - - - 0.000005112 59.0
HKD1_k127_4782081_22 Transposase IS200 like - - - 0.00002868 47.0
HKD1_k127_4782081_23 SNARE associated Golgi protein - - - 0.00009136 53.0
HKD1_k127_4782081_3 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 450.0
HKD1_k127_4782081_4 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 399.0
HKD1_k127_4782081_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 355.0
HKD1_k127_4782081_6 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 355.0
HKD1_k127_4782081_7 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 326.0
HKD1_k127_4782081_8 Cadherin repeats. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 317.0
HKD1_k127_4782081_9 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000181 284.0
HKD1_k127_4788861_0 TonB-dependent receptor - - - 0.0 1491.0
HKD1_k127_4788861_1 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0 1133.0
HKD1_k127_4788861_10 Glycosyl hydrolases family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 340.0
HKD1_k127_4788861_11 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 318.0
HKD1_k127_4788861_12 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005072 274.0
HKD1_k127_4788861_13 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000132 276.0
HKD1_k127_4788861_14 PFAM ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000002399 233.0
HKD1_k127_4788861_15 - - - - 0.00000000000000000000000000000000000000000001058 171.0
HKD1_k127_4788861_16 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000001336 147.0
HKD1_k127_4788861_17 Belongs to the glycosyl hydrolase 26 family - - - 0.000000000000000000002839 103.0
HKD1_k127_4788861_2 Belongs to the glycosyl hydrolase 2 family K01190 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.23 0.0 1043.0
HKD1_k127_4788861_3 Fibronectin type III-like domain K05349 - 3.2.1.21 3.483e-305 954.0
HKD1_k127_4788861_4 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 7.366e-302 946.0
HKD1_k127_4788861_5 Two component regulator propeller - - - 6.639e-267 857.0
HKD1_k127_4788861_6 Belongs to the glycosyl hydrolase 2 family K01192 - 3.2.1.25 1.166e-246 792.0
HKD1_k127_4788861_7 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 639.0
HKD1_k127_4788861_8 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 429.0
HKD1_k127_4788861_9 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 392.0
HKD1_k127_4820168_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 572.0
HKD1_k127_4820168_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 305.0
HKD1_k127_4820168_2 Protein of unknown function (DUF4239) - - - 0.000000000000000000000000000000000000000000000000002581 192.0
HKD1_k127_4820168_3 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000007965 182.0
HKD1_k127_4820168_4 - - - - 0.00000000000000000000000000000000000004769 153.0
HKD1_k127_4820168_5 - - - - 0.0000000000000000000000000000000000001952 146.0
HKD1_k127_4820168_6 N-acetylmannosamine kinase K12409 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006054,GO:0006082,GO:0006793,GO:0006796,GO:0007155,GO:0008150,GO:0008152,GO:0008761,GO:0009058,GO:0009384,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016853,GO:0016854,GO:0016857,GO:0016999,GO:0017000,GO:0017144,GO:0019200,GO:0019752,GO:0022610,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046380,GO:0046394,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576 2.7.1.60,3.2.1.183 0.0002844 47.0
HKD1_k127_4829538_0 AAA ATPase domain - - - 1.298e-311 996.0
HKD1_k127_4829538_1 Carboxypeptidase regulatory-like domain - - - 5.945e-228 744.0
HKD1_k127_4829538_10 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 360.0
HKD1_k127_4829538_11 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 312.0
HKD1_k127_4829538_12 protease with the C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 326.0
HKD1_k127_4829538_13 Chaperone of endosialidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 309.0
HKD1_k127_4829538_14 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001047 279.0
HKD1_k127_4829538_15 Related to alanyl-tRNA synthetase HxxxH domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006549 282.0
HKD1_k127_4829538_17 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000002071 266.0
HKD1_k127_4829538_18 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000005094 269.0
HKD1_k127_4829538_19 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000202 241.0
HKD1_k127_4829538_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 504.0
HKD1_k127_4829538_20 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000002627 237.0
HKD1_k127_4829538_21 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000001359 186.0
HKD1_k127_4829538_22 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000006933 190.0
HKD1_k127_4829538_23 RDD family - - - 0.000000000000000000000000000000000000000000007404 173.0
HKD1_k127_4829538_24 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.0000000000000000000000000000000000006447 145.0
HKD1_k127_4829538_25 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000002609 106.0
HKD1_k127_4829538_26 serine-type peptidase activity - - - 0.000000000000000000005146 98.0
HKD1_k127_4829538_27 Tetratricopeptide repeat - - - 0.000000000000004872 85.0
HKD1_k127_4829538_28 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.00000000000002089 76.0
HKD1_k127_4829538_29 Polymer-forming cytoskeletal - - - 0.000000000005333 74.0
HKD1_k127_4829538_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 458.0
HKD1_k127_4829538_30 Protein of unknown function (DUF2442) - - - 0.00000000001082 68.0
HKD1_k127_4829538_31 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000003356 60.0
HKD1_k127_4829538_33 Domain of unknown function (DUF4160) - - - 0.0006667 44.0
HKD1_k127_4829538_4 A-macroglobulin receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 483.0
HKD1_k127_4829538_5 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 407.0
HKD1_k127_4829538_6 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 405.0
HKD1_k127_4829538_7 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 409.0
HKD1_k127_4829538_8 Permease family K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 402.0
HKD1_k127_4829538_9 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 353.0
HKD1_k127_4878917_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003641 241.0
HKD1_k127_4878917_1 Major intrinsic protein K06188 - - 0.000000000000000000000000000000000000000000000000000000000000523 214.0
HKD1_k127_4878917_2 Transglycosylase associated protein - - - 0.0000000000000000000000000000009749 123.0
HKD1_k127_4878917_3 arylsulfatase activity K01130 - 3.1.6.1 0.000000000000008361 74.0
HKD1_k127_4878917_4 long-chain fatty acid transport protein - - - 0.00002712 53.0
HKD1_k127_4918933_0 amine dehydrogenase activity - - - 3.566e-293 923.0
HKD1_k127_4974890_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.64e-262 829.0
HKD1_k127_4974890_1 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000005946 188.0
HKD1_k127_4974890_2 Thioredoxin - - - 0.0000000000000000000116 98.0
HKD1_k127_4987475_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.257e-231 725.0
HKD1_k127_4987475_1 Phosphotransferase enzyme family - - - 1.569e-213 688.0
HKD1_k127_4987475_10 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 346.0
HKD1_k127_4987475_11 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 309.0
HKD1_k127_4987475_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 299.0
HKD1_k127_4987475_13 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 316.0
HKD1_k127_4987475_14 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 293.0
HKD1_k127_4987475_15 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004775 269.0
HKD1_k127_4987475_16 ethanolamine catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002492 257.0
HKD1_k127_4987475_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006438 258.0
HKD1_k127_4987475_18 dihydrofolate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002819 229.0
HKD1_k127_4987475_19 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000002832 224.0
HKD1_k127_4987475_2 TonB dependent receptor - - - 7.698e-205 684.0
HKD1_k127_4987475_20 AraC family - - - 0.000000000000000000000000000000000000000000000000000000000001388 218.0
HKD1_k127_4987475_21 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000001674 222.0
HKD1_k127_4987475_22 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000001095 218.0
HKD1_k127_4987475_23 - - - - 0.000000000000000000000000000000000000000000000000000001312 200.0
HKD1_k127_4987475_24 Belongs to the peptidase S41A family - - - 0.00000000000000000000000000000000000000000000000004995 196.0
HKD1_k127_4987475_25 Domain of unknown function (DUF4287) - - - 0.00000000000000000000000000000000000000000000002298 175.0
HKD1_k127_4987475_26 Protein of unknown function (DUF1761) - - - 0.000000000000000000000000000000000000000000003829 168.0
HKD1_k127_4987475_27 FAD binding domain K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000001469 174.0
HKD1_k127_4987475_28 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000009744 166.0
HKD1_k127_4987475_29 thiol-disulfide - - - 0.00000000000000000000000000000000000000001936 161.0
HKD1_k127_4987475_3 electron transfer activity K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 512.0
HKD1_k127_4987475_30 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.00000000000000000000000000000000000000198 153.0
HKD1_k127_4987475_31 Redoxin - - - 0.0000000000000000000000000000000000002542 142.0
HKD1_k127_4987475_32 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000001412 124.0
HKD1_k127_4987475_33 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000002657 124.0
HKD1_k127_4987475_34 Transcriptional regulator C-terminal region - - - 0.000000000000000000000000001019 121.0
HKD1_k127_4987475_35 Ferric uptake regulator family K09825 - - 0.000000000000000000000000004645 115.0
HKD1_k127_4987475_36 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000002284 106.0
HKD1_k127_4987475_37 VanZ like family - - - 0.00000000000000000000001407 106.0
HKD1_k127_4987475_38 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000001834 99.0
HKD1_k127_4987475_39 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000001271 74.0
HKD1_k127_4987475_4 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 460.0
HKD1_k127_4987475_40 AAA ATPase domain - - - 0.00000000002602 65.0
HKD1_k127_4987475_41 AhpC/TSA family - - - 0.00000000005533 64.0
HKD1_k127_4987475_42 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000002246 68.0
HKD1_k127_4987475_44 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000003807 64.0
HKD1_k127_4987475_45 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein - - - 0.00001961 53.0
HKD1_k127_4987475_46 - - - - 0.0003671 48.0
HKD1_k127_4987475_47 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0009159 48.0
HKD1_k127_4987475_5 Proline racemase K01777 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 432.0
HKD1_k127_4987475_6 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 410.0
HKD1_k127_4987475_7 virion core protein, lumpy skin disease virus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 398.0
HKD1_k127_4987475_8 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 383.0
HKD1_k127_4987475_9 peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 396.0
HKD1_k127_5027634_0 nodulation K00612 - - 2.482e-264 828.0
HKD1_k127_5027634_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 621.0
HKD1_k127_5027634_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 319.0
HKD1_k127_5027634_11 WbqC-like protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009768 310.0
HKD1_k127_5027634_12 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 297.0
HKD1_k127_5027634_13 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006939 285.0
HKD1_k127_5027634_14 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000857 274.0
HKD1_k127_5027634_15 peptidoglycan biosynthetic process K03980,K21004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002475 277.0
HKD1_k127_5027634_16 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009565 275.0
HKD1_k127_5027634_17 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004776 229.0
HKD1_k127_5027634_18 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000001742 237.0
HKD1_k127_5027634_19 Pfam Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000009519 232.0
HKD1_k127_5027634_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 574.0
HKD1_k127_5027634_20 maltose O-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000944 215.0
HKD1_k127_5027634_21 dTDP-4-dehydrorhamnose 3,5-epimerase - - - 0.000000000000000000000000000000000000000000000000000000006346 203.0
HKD1_k127_5027634_22 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000012 190.0
HKD1_k127_5027634_23 Methyltransferase domain - - - 0.00000000000000000000000000000000000000002967 166.0
HKD1_k127_5027634_24 Small Multidrug Resistance protein - - - 0.0000000000000000000000000000000000000001989 154.0
HKD1_k127_5027634_25 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000001322 151.0
HKD1_k127_5027634_26 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000001125 145.0
HKD1_k127_5027634_27 PFAM DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000002191 140.0
HKD1_k127_5027634_29 protein N-acetylglucosaminyltransferase activity - - - 0.000000000000000000000000000004681 137.0
HKD1_k127_5027634_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 511.0
HKD1_k127_5027634_30 Glycosyl transferase family group 2 K21305 - 2.4.1.335 0.00000000000000000000000000001211 130.0
HKD1_k127_5027634_31 HYR domain - - - 0.000000000000000000000005756 119.0
HKD1_k127_5027634_32 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000005327 94.0
HKD1_k127_5027634_33 - - - - 0.00000000000004776 72.0
HKD1_k127_5027634_36 - - - - 0.00001535 53.0
HKD1_k127_5027634_37 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0002139 53.0
HKD1_k127_5027634_4 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 479.0
HKD1_k127_5027634_5 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 442.0
HKD1_k127_5027634_6 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 394.0
HKD1_k127_5027634_7 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 386.0
HKD1_k127_5027634_8 beta-fructofuranosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 368.0
HKD1_k127_5027634_9 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 345.0
HKD1_k127_5036136_0 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 4.618e-242 760.0
HKD1_k127_5036136_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.159e-220 694.0
HKD1_k127_5036136_10 diphthine-ammonia ligase activity - - - 0.0000000000189 71.0
HKD1_k127_5036136_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 512.0
HKD1_k127_5036136_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 411.0
HKD1_k127_5036136_4 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001735 237.0
HKD1_k127_5036136_5 iron ion homeostasis K02013,K02015 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000003224 234.0
HKD1_k127_5036136_6 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000007944 223.0
HKD1_k127_5036136_7 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000002306 195.0
HKD1_k127_5036136_8 DinB superfamily - - - 0.000000000000000000000001397 110.0
HKD1_k127_5036136_9 transport systems ATPase components K02013 - 3.6.3.34 0.00000000000000002467 85.0
HKD1_k127_5042469_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1088.0
HKD1_k127_5042469_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 2.476e-308 960.0
HKD1_k127_5042469_10 ABC transporter K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 381.0
HKD1_k127_5042469_11 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 379.0
HKD1_k127_5042469_12 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 367.0
HKD1_k127_5042469_13 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 323.0
HKD1_k127_5042469_14 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 321.0
HKD1_k127_5042469_15 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 321.0
HKD1_k127_5042469_16 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 312.0
HKD1_k127_5042469_17 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 299.0
HKD1_k127_5042469_18 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 302.0
HKD1_k127_5042469_19 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 297.0
HKD1_k127_5042469_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.704e-292 918.0
HKD1_k127_5042469_20 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 290.0
HKD1_k127_5042469_21 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001073 276.0
HKD1_k127_5042469_22 SAD/SRA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 261.0
HKD1_k127_5042469_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006896 254.0
HKD1_k127_5042469_24 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000007629 244.0
HKD1_k127_5042469_25 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000001752 243.0
HKD1_k127_5042469_26 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.0000000000000000000000000000000000000000000000000000000000000001536 231.0
HKD1_k127_5042469_27 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000002488 220.0
HKD1_k127_5042469_28 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000008067 216.0
HKD1_k127_5042469_29 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000004363 205.0
HKD1_k127_5042469_3 Dienelactone hydrolase family - - - 4.609e-219 702.0
HKD1_k127_5042469_30 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000001487 197.0
HKD1_k127_5042469_31 - - - - 0.000000000000000000000000000000000000000000000000002725 194.0
HKD1_k127_5042469_32 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000005746 184.0
HKD1_k127_5042469_33 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000003313 181.0
HKD1_k127_5042469_34 Squalene--hopene cyclase - - - 0.00000000000000000000000000000000000000000000000764 176.0
HKD1_k127_5042469_35 - - - - 0.00000000000000000000000000000000000000000000001358 178.0
HKD1_k127_5042469_36 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000001859 177.0
HKD1_k127_5042469_37 - - - - 0.00000000000000000000000000000000000000000000004896 175.0
HKD1_k127_5042469_38 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000003353 183.0
HKD1_k127_5042469_39 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000001471 173.0
HKD1_k127_5042469_4 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 5.227e-210 674.0
HKD1_k127_5042469_40 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000008671 162.0
HKD1_k127_5042469_41 Transposase IS200 like - - - 0.0000000000000000000000000000000000000007319 153.0
HKD1_k127_5042469_42 Protein of unknown function (DUF3224) - - - 0.00000000000000000000000000000000000002985 154.0
HKD1_k127_5042469_43 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.0000000000000000000000000000000000001321 151.0
HKD1_k127_5042469_44 DinB family - - - 0.000000000000000000000000000000001143 136.0
HKD1_k127_5042469_45 - - - - 0.000000000000000000000000000000006453 134.0
HKD1_k127_5042469_46 Ferredoxin K00529,K04755,K08952,K08953,K08954,K15765 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 1.18.1.3 0.000000000000000000000000000003289 134.0
HKD1_k127_5042469_47 Peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000003778 132.0
HKD1_k127_5042469_48 - - - - 0.00000000000000000000000002563 116.0
HKD1_k127_5042469_49 - - - - 0.0000000000000000000000002341 113.0
HKD1_k127_5042469_5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 8.949e-205 654.0
HKD1_k127_5042469_50 - - - - 0.0000000000000000000000006841 110.0
HKD1_k127_5042469_51 Belongs to the ompA family - - - 0.00000000000000000000002141 112.0
HKD1_k127_5042469_52 Tetratricopeptide repeat - - - 0.00000000000000000005653 100.0
HKD1_k127_5042469_53 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000001219 96.0
HKD1_k127_5042469_54 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.00000000000000001046 89.0
HKD1_k127_5042469_55 Methionine biosynthesis protein MetW - - - 0.000000000000009663 84.0
HKD1_k127_5042469_57 Domain of unknown function (DUF4956) - - - 0.00000000005419 74.0
HKD1_k127_5042469_58 Glucose sorbosone - - - 0.0000000001076 71.0
HKD1_k127_5042469_59 Tetratricopeptide repeat - - - 0.00000000236 69.0
HKD1_k127_5042469_6 transmembrane transporter activity K08196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 612.0
HKD1_k127_5042469_60 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000001287 65.0
HKD1_k127_5042469_61 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.0000006161 56.0
HKD1_k127_5042469_62 Copper binding periplasmic protein CusF - - - 0.000005387 54.0
HKD1_k127_5042469_63 - - - - 0.000009926 53.0
HKD1_k127_5042469_7 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 586.0
HKD1_k127_5042469_8 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 422.0
HKD1_k127_5042469_9 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 399.0
HKD1_k127_5140315_0 Tricorn protease C1 domain K08676 - - 0.0 1285.0
HKD1_k127_5140315_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.288e-287 894.0
HKD1_k127_5140315_10 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 451.0
HKD1_k127_5140315_11 PFAM Acetamidase Formamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 455.0
HKD1_k127_5140315_12 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 467.0
HKD1_k127_5140315_13 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 438.0
HKD1_k127_5140315_14 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 413.0
HKD1_k127_5140315_15 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 363.0
HKD1_k127_5140315_16 Peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 365.0
HKD1_k127_5140315_17 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 349.0
HKD1_k127_5140315_18 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 353.0
HKD1_k127_5140315_19 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 302.0
HKD1_k127_5140315_2 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 4.032e-217 685.0
HKD1_k127_5140315_20 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 301.0
HKD1_k127_5140315_21 Oxidoreductase NAD-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 301.0
HKD1_k127_5140315_22 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003508 285.0
HKD1_k127_5140315_23 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009289 287.0
HKD1_k127_5140315_24 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007485 269.0
HKD1_k127_5140315_25 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001327 268.0
HKD1_k127_5140315_26 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008413 274.0
HKD1_k127_5140315_27 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000007706 256.0
HKD1_k127_5140315_28 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008122 271.0
HKD1_k127_5140315_29 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000517 210.0
HKD1_k127_5140315_3 Major facilitator Superfamily K08178 - - 3.299e-197 621.0
HKD1_k127_5140315_30 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000001518 204.0
HKD1_k127_5140315_31 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000001846 206.0
HKD1_k127_5140315_32 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000009005 208.0
HKD1_k127_5140315_33 Protein of unknown function, DUF480 K09915 - - 0.00000000000000000000000000000000000000000000000000002876 195.0
HKD1_k127_5140315_34 - - - - 0.000000000000000000000000000000000000000000000000001029 208.0
HKD1_k127_5140315_35 PFAM Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000954 190.0
HKD1_k127_5140315_36 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000001845 199.0
HKD1_k127_5140315_38 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000402 184.0
HKD1_k127_5140315_39 EVE domain - - - 0.000000000000000000000000000000000000000000000005634 176.0
HKD1_k127_5140315_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.018e-194 619.0
HKD1_k127_5140315_40 OHCU decarboxylase K16840 - 4.1.1.97 0.00000000000000000000000000000000000000000005649 165.0
HKD1_k127_5140315_41 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000001406 172.0
HKD1_k127_5140315_42 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000000000557 156.0
HKD1_k127_5140315_43 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000002369 156.0
HKD1_k127_5140315_44 - - - - 0.00000000000000000000000000000000000000006009 160.0
HKD1_k127_5140315_45 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000006225 162.0
HKD1_k127_5140315_46 RDD family - - - 0.0000000000000000000000000000000000001368 147.0
HKD1_k127_5140315_47 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000009098 141.0
HKD1_k127_5140315_48 - - - - 0.000000000000000000000000000000000001862 142.0
HKD1_k127_5140315_49 Hemolysin-type calcium-binding repeat (2 copies) K01183 - 3.2.1.14 0.0000000000000000000000000000001097 138.0
HKD1_k127_5140315_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 614.0
HKD1_k127_5140315_50 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000006128 129.0
HKD1_k127_5140315_51 response to abiotic stimulus - - - 0.0000000000000000000000000008071 128.0
HKD1_k127_5140315_52 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000008827 111.0
HKD1_k127_5140315_53 Domain of unknown function (DUF4347) - - - 0.0000000000000000000002055 108.0
HKD1_k127_5140315_54 SEC-C Motif Domain Protein - - - 0.00000000000000000003891 97.0
HKD1_k127_5140315_55 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000008395 95.0
HKD1_k127_5140315_56 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000001225 95.0
HKD1_k127_5140315_57 - - - - 0.0000000000000000003913 103.0
HKD1_k127_5140315_58 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000000000001687 85.0
HKD1_k127_5140315_59 Carbohydrate binding domain - - - 0.00000000000000003325 96.0
HKD1_k127_5140315_6 ATP dependent DNA ligase C terminal region K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 585.0
HKD1_k127_5140315_60 Cytochrome c K00406,K08906 - - 0.00000000002564 69.0
HKD1_k127_5140315_62 mttA/Hcf106 family K03116,K03117 - - 0.00000001377 61.0
HKD1_k127_5140315_63 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000002597 53.0
HKD1_k127_5140315_64 - - - - 0.000003247 57.0
HKD1_k127_5140315_66 Biopolymer transport protein K03559 - - 0.000005944 57.0
HKD1_k127_5140315_7 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 568.0
HKD1_k127_5140315_8 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 550.0
HKD1_k127_5140315_9 Peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 469.0
HKD1_k127_5141751_0 Domain of unknown function (DUF1972) K12996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 402.0
HKD1_k127_5149119_0 PFAM Amidase - - - 4.673e-268 836.0
HKD1_k127_5149119_1 Phosphate acyltransferases K01897 - 6.2.1.3 1.728e-245 786.0
HKD1_k127_5149119_10 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 415.0
HKD1_k127_5149119_11 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 386.0
HKD1_k127_5149119_12 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 379.0
HKD1_k127_5149119_13 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 361.0
HKD1_k127_5149119_14 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 357.0
HKD1_k127_5149119_15 glucosamine-6-phosphate deaminase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 338.0
HKD1_k127_5149119_16 Belongs to the glycosyl hydrolase 28 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 296.0
HKD1_k127_5149119_17 Zgc 162297 K06971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005466 280.0
HKD1_k127_5149119_18 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000000009234 256.0
HKD1_k127_5149119_19 FCD K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000009913 241.0
HKD1_k127_5149119_2 N-terminal double-glycine peptidase domain K06147 - - 2.644e-229 745.0
HKD1_k127_5149119_20 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000004228 224.0
HKD1_k127_5149119_21 Uncharacterised conserved protein (DUF2156) K14205 - 2.3.2.3 0.000000000000000000000000000000000000000000000000000000000000003883 232.0
HKD1_k127_5149119_22 - - - - 0.00000000000000000000000000000000000000000000000000000000004956 208.0
HKD1_k127_5149119_23 PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000003207 196.0
HKD1_k127_5149119_24 YwiC-like protein - - - 0.00000000000000000000000000000000000000000000000000001466 200.0
HKD1_k127_5149119_25 histidine kinase, HAMP - - - 0.000000000000000000000000000000000000000000000000001183 203.0
HKD1_k127_5149119_26 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000000000000000000000000000000000003728 178.0
HKD1_k127_5149119_27 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000007323 167.0
HKD1_k127_5149119_28 peptidyl-arginine hydroxylation - - - 0.0000000000000000000000000000000000000002878 166.0
HKD1_k127_5149119_29 cellulose binding - - - 0.00000000000000000000000000000009218 147.0
HKD1_k127_5149119_3 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 577.0
HKD1_k127_5149119_30 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001073 139.0
HKD1_k127_5149119_31 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.000000000000000000000000000007502 130.0
HKD1_k127_5149119_32 7TMR-DISM extracellular 2 - - - 0.0000000000000000000000000000302 129.0
HKD1_k127_5149119_33 SPTR Oxidoreductase of the aldo keto reductase family-like protein - - - 0.000000000000000000000001232 115.0
HKD1_k127_5149119_34 Putative Ig domain - - - 0.00000000000000000000003958 116.0
HKD1_k127_5149119_35 - - - - 0.0000000000000000003987 88.0
HKD1_k127_5149119_36 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000002124 87.0
HKD1_k127_5149119_37 conserved protein, contains double-stranded beta-helix domain - - - 0.00000000000000001362 88.0
HKD1_k127_5149119_39 SNARE associated Golgi protein - - - 0.00000000005233 70.0
HKD1_k127_5149119_4 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 587.0
HKD1_k127_5149119_40 Uncharacterised conserved protein (DUF2156) - - - 0.0000000006619 70.0
HKD1_k127_5149119_41 O-antigen ligase like membrane protein - - - 0.00000006155 66.0
HKD1_k127_5149119_42 Bacterial virulence protein (VirJ) - - - 0.0000002289 62.0
HKD1_k127_5149119_44 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000005992 53.0
HKD1_k127_5149119_45 Uncharacterised conserved protein (DUF2156) - - - 0.000006343 58.0
HKD1_k127_5149119_46 'glutamate synthase - - - 0.00002064 51.0
HKD1_k127_5149119_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 571.0
HKD1_k127_5149119_6 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 559.0
HKD1_k127_5149119_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 558.0
HKD1_k127_5149119_8 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 562.0
HKD1_k127_5149119_9 RimK-like ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 449.0
HKD1_k127_5184943_0 serine threonine protein kinase K12132 - 2.7.11.1 1.158e-198 654.0
HKD1_k127_5184943_1 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 329.0
HKD1_k127_5184943_10 YGGT family K02221 - - 0.00000000006987 71.0
HKD1_k127_5184943_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000001295 239.0
HKD1_k127_5184943_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000005985 213.0
HKD1_k127_5184943_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000007658 160.0
HKD1_k127_5184943_5 pathogenesis K01337,K04771,K20276,K21449 - 3.4.21.107,3.4.21.50 0.000000000000000000000000000000000000003838 170.0
HKD1_k127_5184943_6 cellulose binding - - - 0.00000000000000000000008058 116.0
HKD1_k127_5184943_7 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000001062 115.0
HKD1_k127_5184943_8 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - 0.0000000000000000000005213 113.0
HKD1_k127_5184943_9 Belongs to the UPF0235 family K09131 - - 0.0000000000000000001889 92.0
HKD1_k127_5194179_0 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 337.0
HKD1_k127_5194179_1 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 291.0
HKD1_k127_5194179_10 Tetratricopeptide repeat - - - 0.00005475 52.0
HKD1_k127_5194179_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007497 286.0
HKD1_k127_5194179_4 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000009818 232.0
HKD1_k127_5194179_5 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000001092 183.0
HKD1_k127_5194179_6 endoribonuclease - - - 0.0000000000000000000000000000000004468 137.0
HKD1_k127_5194179_7 Ion channel - - - 0.0000000000000000000000000123 120.0
HKD1_k127_5194179_8 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.00000000000000000000000001681 115.0
HKD1_k127_5197982_0 AMP-binding enzyme C-terminal domain K00666 - - 3.081e-253 789.0
HKD1_k127_5197982_1 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000003963 214.0
HKD1_k127_5197982_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000007837 212.0
HKD1_k127_5197982_3 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000000000000000000000000004458 172.0
HKD1_k127_5197982_4 Protein of unknown function (DUF1569) - - - 0.000000000000000000000000000000000000000005153 159.0
HKD1_k127_5241654_0 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 6.35e-255 799.0
HKD1_k127_5241654_1 response to abiotic stimulus K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 510.0
HKD1_k127_5241654_2 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 366.0
HKD1_k127_5241654_3 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 322.0
HKD1_k127_5241654_4 Pfam RibD C-terminal domain K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000006766 245.0
HKD1_k127_5241654_5 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000009051 220.0
HKD1_k127_5241654_6 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000002454 213.0
HKD1_k127_5241654_7 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000007234 194.0
HKD1_k127_5241654_8 - - - - 0.0000000000000000000000006463 115.0
HKD1_k127_5241654_9 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000001096 93.0
HKD1_k127_5279605_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 7.208e-246 769.0
HKD1_k127_5279605_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.828e-209 660.0
HKD1_k127_5279605_10 Fibronectin type 3 domain - - - 0.000000000000000000000000001565 125.0
HKD1_k127_5279605_11 Psort location Cytoplasmic, score K07586 - - 0.000000000000003585 81.0
HKD1_k127_5279605_13 lytic transglycosylase activity K03194 - - 0.00000000000462 78.0
HKD1_k127_5279605_14 PFAM glutamine amidotransferase class-I K07010 - - 0.00000000004396 68.0
HKD1_k127_5279605_2 abc transporter atp-binding protein K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003512 287.0
HKD1_k127_5279605_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K08314 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002271 278.0
HKD1_k127_5279605_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000005306 250.0
HKD1_k127_5279605_5 - - - - 0.00000000000000000000000000000000000000000000001362 184.0
HKD1_k127_5279605_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000002861 168.0
HKD1_k127_5279605_7 PFAM ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000001089 160.0
HKD1_k127_5279605_8 - - - - 0.0000000000000000000000000000000000007223 156.0
HKD1_k127_5279605_9 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000007403 113.0
HKD1_k127_5289387_0 Class II Aldolase and Adducin N-terminal domain K00001,K01629 - 1.1.1.1,4.1.2.19 0.0 1017.0
HKD1_k127_5289387_1 isomerase K01820 - 5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000001226 217.0
HKD1_k127_5289387_2 FCD - - - 0.00000000000000000000000000000000000003596 151.0
HKD1_k127_5329304_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 542.0
HKD1_k127_5329304_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 479.0
HKD1_k127_5329304_10 secreted Zn-dependent protease - - - 0.00003093 54.0
HKD1_k127_5329304_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 467.0
HKD1_k127_5329304_3 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 377.0
HKD1_k127_5329304_4 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002153 264.0
HKD1_k127_5329304_5 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000002128 222.0
HKD1_k127_5329304_6 Haemolysin-type calcium-binding repeat - - - 0.00000000000000000000000000000000000000000000000001676 196.0
HKD1_k127_5329304_7 - - - - 0.000000000000000000000000000000006274 141.0
HKD1_k127_5329304_8 Protein of unknown function (DUF1353) - - - 0.000000000000000000000000000006073 128.0
HKD1_k127_5331996_0 DEAD DEAH box helicase K03724 - - 0.0 1701.0
HKD1_k127_5331996_1 Sortilin, neurotensin receptor 3, - - - 0.0 1436.0
HKD1_k127_5331996_10 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 470.0
HKD1_k127_5331996_11 PFAM ATP dependent DNA ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 457.0
HKD1_k127_5331996_12 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 460.0
HKD1_k127_5331996_13 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 457.0
HKD1_k127_5331996_14 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 430.0
HKD1_k127_5331996_15 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 442.0
HKD1_k127_5331996_16 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009994 413.0
HKD1_k127_5331996_17 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 409.0
HKD1_k127_5331996_18 class I DNA-(apurinic or apyrimidinic site) endonuclease activity K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 378.0
HKD1_k127_5331996_19 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 350.0
HKD1_k127_5331996_2 Beta-lactamase class C - - - 2.221e-244 769.0
HKD1_k127_5331996_20 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 325.0
HKD1_k127_5331996_21 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 307.0
HKD1_k127_5331996_22 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 308.0
HKD1_k127_5331996_23 PFAM Basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 305.0
HKD1_k127_5331996_24 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002374 287.0
HKD1_k127_5331996_25 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000001627 248.0
HKD1_k127_5331996_26 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001262 248.0
HKD1_k127_5331996_27 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000004718 225.0
HKD1_k127_5331996_28 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001018 209.0
HKD1_k127_5331996_29 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000005596 198.0
HKD1_k127_5331996_3 Protein of unknown function (DUF763) K09003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 563.0
HKD1_k127_5331996_30 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000001269 181.0
HKD1_k127_5331996_31 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000104 177.0
HKD1_k127_5331996_32 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000002128 173.0
HKD1_k127_5331996_33 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000001031 160.0
HKD1_k127_5331996_34 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000001972 156.0
HKD1_k127_5331996_35 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000005842 145.0
HKD1_k127_5331996_36 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000002638 149.0
HKD1_k127_5331996_37 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000006271 143.0
HKD1_k127_5331996_38 ArsC family - - - 0.000000000000000000000000000000000002938 141.0
HKD1_k127_5331996_39 Membrane - - - 0.000000000000000000000000000000000008143 143.0
HKD1_k127_5331996_4 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 549.0
HKD1_k127_5331996_40 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.000000000000000000000000000000002255 132.0
HKD1_k127_5331996_41 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000000000003648 130.0
HKD1_k127_5331996_42 EamA-like transporter family - - - 0.00000000000000000000000000000005534 130.0
HKD1_k127_5331996_43 Domain of unknown function (DUF4160) - - - 0.000000000000000000000000000000501 124.0
HKD1_k127_5331996_44 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000004331 119.0
HKD1_k127_5331996_45 Belongs to the ompA family - - - 0.0000000000000000000000000005556 125.0
HKD1_k127_5331996_46 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000004981 113.0
HKD1_k127_5331996_48 Methanol dehydrogenase K06872 - - 0.000000000000000000000001556 114.0
HKD1_k127_5331996_49 COG3668 Plasmid stabilization system protein - - - 0.000000000000000000000003229 104.0
HKD1_k127_5331996_5 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 544.0
HKD1_k127_5331996_50 cellulase activity - - - 0.0000000000000000000001628 113.0
HKD1_k127_5331996_51 Acetyltransferase (GNAT) domain - - - 0.000000000000000000002119 99.0
HKD1_k127_5331996_52 - - - - 0.000000000000000001239 93.0
HKD1_k127_5331996_53 - - - - 0.000000000000004102 78.0
HKD1_k127_5331996_54 Prokaryotic N-terminal methylation motif - - - 0.00000000000004503 85.0
HKD1_k127_5331996_55 TIGRFAM TonB family K03832 - - 0.00000000001709 74.0
HKD1_k127_5331996_57 Collagen triple helix repeat (20 copies) - - - 0.0000004169 60.0
HKD1_k127_5331996_59 Peptidase, M28 - - - 0.0006291 42.0
HKD1_k127_5331996_6 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 533.0
HKD1_k127_5331996_7 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 518.0
HKD1_k127_5331996_8 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009473 505.0
HKD1_k127_5331996_9 Domain of unknown function (DUF4070) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 503.0
HKD1_k127_5347374_0 TonB-dependent receptor - - - 0.0 1091.0
HKD1_k127_5347374_1 alpha-L-rhamnosidase - - - 6.716e-292 924.0
HKD1_k127_5347374_2 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 3.331e-201 644.0
HKD1_k127_5347374_3 Glycosyl hydrolases family 2, sugar binding domain K01190 - 3.2.1.23 4.307e-199 632.0
HKD1_k127_5347374_4 Sialate O-acetylesterase K05970 - 3.1.1.53 1.464e-197 628.0
HKD1_k127_5347374_5 polygalacturonase activity K01184 - 3.2.1.15 2.415e-197 627.0
HKD1_k127_5347374_6 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000006093 186.0
HKD1_k127_5351193_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.49e-273 854.0
HKD1_k127_5351193_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 508.0
HKD1_k127_5351193_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 309.0
HKD1_k127_5351193_11 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000002626 214.0
HKD1_k127_5351193_12 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000002994 194.0
HKD1_k127_5351193_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000003213 175.0
HKD1_k127_5351193_14 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000003603 170.0
HKD1_k127_5351193_15 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000002592 162.0
HKD1_k127_5351193_16 BMC domain - - - 0.000000000000000000000000000000001391 131.0
HKD1_k127_5351193_17 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000000000007249 121.0
HKD1_k127_5351193_18 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000000000000000004757 95.0
HKD1_k127_5351193_19 Belongs to the UPF0761 family K07058 - - 0.00000000000000000001917 102.0
HKD1_k127_5351193_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 436.0
HKD1_k127_5351193_20 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000005524 83.0
HKD1_k127_5351193_21 Tetratricopeptide repeat - - - 0.00000000007256 72.0
HKD1_k127_5351193_22 PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0002622 49.0
HKD1_k127_5351193_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 437.0
HKD1_k127_5351193_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 384.0
HKD1_k127_5351193_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 355.0
HKD1_k127_5351193_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 356.0
HKD1_k127_5351193_7 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 307.0
HKD1_k127_5351193_8 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 316.0
HKD1_k127_5351193_9 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 304.0
HKD1_k127_5385321_0 elongation factor Tu domain 2 protein K06207 - - 2.29e-215 678.0
HKD1_k127_5385321_1 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 608.0
HKD1_k127_5385321_11 - - - - 0.0000000000000000000000000002613 121.0
HKD1_k127_5385321_13 - - - - 0.0000000001432 71.0
HKD1_k127_5385321_2 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 290.0
HKD1_k127_5385321_3 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009663 247.0
HKD1_k127_5385321_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004975 258.0
HKD1_k127_5385321_5 Hydrogen peroxide-inducible genes activator K04761,K11921 - - 0.00000000000000000000000000000000000000000000000000000000001239 218.0
HKD1_k127_5385321_6 - - - - 0.00000000000000000000000000000000000000000000000000000000009079 214.0
HKD1_k127_5385321_7 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000009402 183.0
HKD1_k127_5385321_8 Nuclear protein SET K07117 - - 0.0000000000000000000000000000000000000000000000001078 181.0
HKD1_k127_5385321_9 alpha-ribazole phosphatase activity - - - 0.0000000000000000000000000000000000000000000000001433 183.0
HKD1_k127_5410285_0 PFAM peptidase M16 domain protein K07263 - - 2.27e-322 1008.0
HKD1_k127_5410285_1 - - - - 0.00000000000000000000000000000000000000000000000002374 197.0
HKD1_k127_5410285_2 - - - - 0.00000000000000000000000000000000000000001532 158.0
HKD1_k127_5456175_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.506e-195 619.0
HKD1_k127_5456175_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 584.0
HKD1_k127_5456175_10 PFAM ABC transporter related K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 317.0
HKD1_k127_5456175_11 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006379 289.0
HKD1_k127_5456175_13 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000001246 225.0
HKD1_k127_5456175_14 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000007887 226.0
HKD1_k127_5456175_15 - - - - 0.000000000000000000000000000000000000000000000000000000002563 214.0
HKD1_k127_5456175_16 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000002761 192.0
HKD1_k127_5456175_17 DinB superfamily K07552 - - 0.000000000000000000000000000000000004179 143.0
HKD1_k127_5456175_18 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000007478 143.0
HKD1_k127_5456175_19 - - - - 0.000000000000000000000001173 107.0
HKD1_k127_5456175_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 510.0
HKD1_k127_5456175_20 - - - - 0.00004876 49.0
HKD1_k127_5456175_3 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 507.0
HKD1_k127_5456175_4 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 458.0
HKD1_k127_5456175_5 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 430.0
HKD1_k127_5456175_6 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 410.0
HKD1_k127_5456175_7 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 384.0
HKD1_k127_5456175_8 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 365.0
HKD1_k127_5456175_9 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 348.0
HKD1_k127_5493256_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.0 1178.0
HKD1_k127_5493256_1 hydrolase family 92 - - - 4.157e-309 975.0
HKD1_k127_5493256_10 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000000000000000000353 206.0
HKD1_k127_5493256_11 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000001191 192.0
HKD1_k127_5493256_12 - - - - 0.00000000000000000000000000000000000000000000002183 178.0
HKD1_k127_5493256_13 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000007038 121.0
HKD1_k127_5493256_14 Murein transglycosylase - - - 0.000000000007001 75.0
HKD1_k127_5493256_2 glycolate transport K14393 - - 3.283e-243 761.0
HKD1_k127_5493256_3 Protein tyrosine kinase - - - 6.514e-216 700.0
HKD1_k127_5493256_4 Glycoside hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 599.0
HKD1_k127_5493256_5 PFAM sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009674 530.0
HKD1_k127_5493256_6 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 517.0
HKD1_k127_5493256_7 transferase activity, transferring glycosyl groups K15521 - 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 348.0
HKD1_k127_5493256_8 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 334.0
HKD1_k127_5493256_9 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005596 290.0
HKD1_k127_5576100_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 4.221e-288 903.0
HKD1_k127_5576100_1 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 548.0
HKD1_k127_5576100_2 OmpA family K02557,K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 477.0
HKD1_k127_5576100_3 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000001182 219.0
HKD1_k127_5576100_4 TIGRFAM Small GTP-binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000001036 196.0
HKD1_k127_5576100_5 Protein conserved in bacteria - - - 0.0000000000000000000000000000000002968 139.0
HKD1_k127_5576100_6 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000005474 110.0
HKD1_k127_5578032_0 Tricorn protease homolog - - - 0.0 1270.0
HKD1_k127_5578032_1 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1220.0
HKD1_k127_5578032_10 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 439.0
HKD1_k127_5578032_11 nitric oxide reductase activity K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 415.0
HKD1_k127_5578032_12 Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 398.0
HKD1_k127_5578032_13 phenazine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 370.0
HKD1_k127_5578032_14 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 355.0
HKD1_k127_5578032_15 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 367.0
HKD1_k127_5578032_16 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 348.0
HKD1_k127_5578032_17 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 377.0
HKD1_k127_5578032_18 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002454 306.0
HKD1_k127_5578032_19 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007692 275.0
HKD1_k127_5578032_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 1.078e-254 799.0
HKD1_k127_5578032_20 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000002108 263.0
HKD1_k127_5578032_21 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002345 283.0
HKD1_k127_5578032_22 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008521 263.0
HKD1_k127_5578032_23 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001073 264.0
HKD1_k127_5578032_24 enzyme related to lactoylglutathione lyase K06996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001573 261.0
HKD1_k127_5578032_25 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007565 254.0
HKD1_k127_5578032_26 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000002676 243.0
HKD1_k127_5578032_27 esterase lipase - - - 0.0000000000000000000000000000000000000000000000000000000000008949 223.0
HKD1_k127_5578032_28 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000002303 211.0
HKD1_k127_5578032_29 Protein of unknown function (DUF4199) - - - 0.00000000000000000000000000000000000000000000000000000001358 202.0
HKD1_k127_5578032_3 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 6.212e-197 623.0
HKD1_k127_5578032_30 EamA-like transporter family K07790 - - 0.000000000000000000000000000000000000000000000000006947 192.0
HKD1_k127_5578032_31 - - - - 0.00000000000000000000000000000000000000000000000000802 185.0
HKD1_k127_5578032_32 DinB family - - - 0.000000000000000000000000000000000000000000000000008235 184.0
HKD1_k127_5578032_33 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000003416 188.0
HKD1_k127_5578032_34 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000003638 177.0
HKD1_k127_5578032_35 Protein of unknown function (DUF3465) - - - 0.00000000000000000000000000000000000000001383 158.0
HKD1_k127_5578032_36 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000004727 145.0
HKD1_k127_5578032_37 - - - - 0.00000000000000000000000000000000001737 143.0
HKD1_k127_5578032_38 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000005627 133.0
HKD1_k127_5578032_39 ARD/ARD' family - - - 0.00000000000000000000000000000003238 128.0
HKD1_k127_5578032_4 gluconolactonase activity K01053,K13735 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 614.0
HKD1_k127_5578032_40 Phosphoglycerate mutase family - - - 0.0000000000000000000000006036 112.0
HKD1_k127_5578032_41 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000001146 104.0
HKD1_k127_5578032_42 - - - - 0.00000000000000000001138 97.0
HKD1_k127_5578032_43 - - - - 0.00000000000000000003019 98.0
HKD1_k127_5578032_44 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000001411 101.0
HKD1_k127_5578032_45 CBS domain - - - 0.0000000000000000009852 92.0
HKD1_k127_5578032_47 Polymer-forming cytoskeletal - - - 0.0000000000001755 76.0
HKD1_k127_5578032_48 - - - - 0.000000000002221 76.0
HKD1_k127_5578032_5 PFAM NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 623.0
HKD1_k127_5578032_50 Beta-L-arabinofuranosidase, GH127 - - - 0.00000003243 65.0
HKD1_k127_5578032_51 - - - - 0.00000005262 64.0
HKD1_k127_5578032_52 DNA-templated transcription, initiation K02405 - - 0.000003549 49.0
HKD1_k127_5578032_53 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 0.0000112 53.0
HKD1_k127_5578032_54 lipolytic protein G-D-S-L family - - - 0.00001448 56.0
HKD1_k127_5578032_55 Enoyl-(Acyl carrier protein) reductase - - - 0.00007865 48.0
HKD1_k127_5578032_56 Anti-sigma-K factor rskA - - - 0.0001887 52.0
HKD1_k127_5578032_6 PFAM Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 595.0
HKD1_k127_5578032_7 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 567.0
HKD1_k127_5578032_8 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 522.0
HKD1_k127_5578032_9 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 454.0
HKD1_k127_5579860_0 Carboxypeptidase regulatory-like domain - - - 3.539e-251 811.0
HKD1_k127_5579860_1 Carboxypeptidase regulatory-like domain - - - 1.168e-239 775.0
HKD1_k127_5579860_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 498.0
HKD1_k127_5579860_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007078 276.0
HKD1_k127_5579860_4 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000001665 220.0
HKD1_k127_5579860_5 Tetratricopeptide repeat - - - 0.00000000000000002784 89.0
HKD1_k127_5626142_0 PFAM Prolyl oligopeptidase family - - - 2.459e-280 874.0
HKD1_k127_5626142_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 543.0
HKD1_k127_5626142_10 NUDIX domain K03574 - 3.6.1.55 0.000000001357 64.0
HKD1_k127_5626142_11 Protein of unknown function (DUF3995) - - - 0.000000009908 63.0
HKD1_k127_5626142_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 391.0
HKD1_k127_5626142_3 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000759 253.0
HKD1_k127_5626142_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000212 218.0
HKD1_k127_5626142_5 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000001652 209.0
HKD1_k127_5626142_6 cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000139 186.0
HKD1_k127_5626142_7 Cold-shock protein, DNA-binding - - - 0.00000000000000000000000000000000000000001158 160.0
HKD1_k127_5626142_8 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000002573 158.0
HKD1_k127_5626142_9 - - - - 0.00000000000005355 79.0
HKD1_k127_5658301_0 Putative glucoamylase K13688 - - 0.0 2651.0
HKD1_k127_5658301_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1181.0
HKD1_k127_5658301_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 399.0
HKD1_k127_5658301_11 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 357.0
HKD1_k127_5658301_12 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 357.0
HKD1_k127_5658301_13 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 335.0
HKD1_k127_5658301_14 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 295.0
HKD1_k127_5658301_15 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001442 316.0
HKD1_k127_5658301_16 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004013 289.0
HKD1_k127_5658301_17 Tail Collar domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002263 253.0
HKD1_k127_5658301_18 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007507 281.0
HKD1_k127_5658301_19 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000001725 236.0
HKD1_k127_5658301_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2.705e-285 899.0
HKD1_k127_5658301_20 Tail Collar domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004655 226.0
HKD1_k127_5658301_21 PFAM Phage tail collar - - - 0.000000000000000000000000000000000000000000000000000000000000000131 225.0
HKD1_k127_5658301_22 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000004519 199.0
HKD1_k127_5658301_23 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000005302 214.0
HKD1_k127_5658301_24 PFAM Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000543 204.0
HKD1_k127_5658301_25 JAB/MPN domain - - - 0.0000000000000000000000000000000000000000002439 164.0
HKD1_k127_5658301_26 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000003159 164.0
HKD1_k127_5658301_27 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000002669 147.0
HKD1_k127_5658301_28 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000033 166.0
HKD1_k127_5658301_29 oxidoreductase activity - - - 0.00000000000000000000000000000001904 150.0
HKD1_k127_5658301_3 Carboxypeptidase regulatory-like domain - - - 8.608e-277 886.0
HKD1_k127_5658301_30 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0000000000000000000000000000001443 145.0
HKD1_k127_5658301_31 FR47-like protein - - - 0.000000000000000000000000000001577 126.0
HKD1_k127_5658301_32 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000005288 111.0
HKD1_k127_5658301_33 Bacterial Ig-like domain (group 3) K20276 - - 0.00000000000000000000002784 120.0
HKD1_k127_5658301_34 Extracellular nuclease - - - 0.000000000000000000002233 113.0
HKD1_k127_5658301_35 methyltransferase - - - 0.00000000000000000001341 107.0
HKD1_k127_5658301_36 cell redox homeostasis K02199 - - 0.000000000000000001431 94.0
HKD1_k127_5658301_37 Cupin 2, conserved barrel domain protein - - - 0.00000000000002245 80.0
HKD1_k127_5658301_38 - - - - 0.000000000000855 72.0
HKD1_k127_5658301_39 peptidyl-tyrosine sulfation - - - 0.0000000003152 72.0
HKD1_k127_5658301_4 ThiS family K21029,K21147 - 2.7.7.80,2.8.1.11 3.496e-196 623.0
HKD1_k127_5658301_41 lipase activity K01406 - 3.4.24.40 0.0000003978 64.0
HKD1_k127_5658301_42 - - - - 0.00001419 54.0
HKD1_k127_5658301_43 - - - - 0.00007111 51.0
HKD1_k127_5658301_5 imidazolonepropionase activity K00466 - 1.13.12.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 537.0
HKD1_k127_5658301_6 Acyl-CoA dehydrogenase, N-terminal domain K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 516.0
HKD1_k127_5658301_7 ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 441.0
HKD1_k127_5658301_8 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 409.0
HKD1_k127_5658301_9 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 399.0
HKD1_k127_5684666_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 9.602e-295 931.0
HKD1_k127_5684666_1 PFAM peptidase M13 K01415 - 3.4.24.71 4.864e-208 668.0
HKD1_k127_5684666_2 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007124 271.0
HKD1_k127_5684666_3 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000002475 179.0
HKD1_k127_5684666_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000008278 169.0
HKD1_k127_5684666_5 von Willebrand factor, type A - - - 0.00000000000000000000001166 116.0
HKD1_k127_5684666_6 Lanthionine synthetase C family protein - - - 0.0000000000000000000001138 113.0
HKD1_k127_5703806_0 cellulose binding - - - 0.0 1599.0
HKD1_k127_5703806_1 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 8.694e-259 812.0
HKD1_k127_5703806_10 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 319.0
HKD1_k127_5703806_11 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 299.0
HKD1_k127_5703806_12 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001756 284.0
HKD1_k127_5703806_13 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004702 292.0
HKD1_k127_5703806_14 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001933 263.0
HKD1_k127_5703806_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006791 261.0
HKD1_k127_5703806_16 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000849 224.0
HKD1_k127_5703806_17 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000482 223.0
HKD1_k127_5703806_18 Metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000007932 185.0
HKD1_k127_5703806_19 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000001659 169.0
HKD1_k127_5703806_2 TonB dependent receptor K16090 - - 9.24e-220 706.0
HKD1_k127_5703806_20 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000000000000000000000000000007326 155.0
HKD1_k127_5703806_21 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000001776 145.0
HKD1_k127_5703806_22 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000000000002312 142.0
HKD1_k127_5703806_23 Rieske-like [2Fe-2S] domain K05710,K14578 - - 0.000000000000000000000000000000009087 129.0
HKD1_k127_5703806_24 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000003802 124.0
HKD1_k127_5703806_25 - - - - 0.00000000000000000000005095 103.0
HKD1_k127_5703806_26 PFAM amine oxidase - - - 0.00000000000000000009646 90.0
HKD1_k127_5703806_27 peptidase M15B and M15C DD-carboxypeptidase VanY - - - 0.00000000000000001356 92.0
HKD1_k127_5703806_28 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000006923 92.0
HKD1_k127_5703806_29 Tetratricopeptide repeat - - - 0.0000000000000001014 94.0
HKD1_k127_5703806_3 SMART Elongator protein 3 MiaB NifB - - - 1.023e-216 684.0
HKD1_k127_5703806_30 - - - - 0.0000000009808 67.0
HKD1_k127_5703806_31 Outer membrane protein (OmpH-like) K06142 - - 0.000000002487 68.0
HKD1_k127_5703806_32 Outer membrane protein (OmpH-like) K06142 - - 0.000000003924 65.0
HKD1_k127_5703806_34 Domain of unknown function (DUF4388) - - - 0.0001433 53.0
HKD1_k127_5703806_4 PFAM FAD dependent oxidoreductase - - - 4.086e-206 653.0
HKD1_k127_5703806_5 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 537.0
HKD1_k127_5703806_6 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 434.0
HKD1_k127_5703806_7 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 430.0
HKD1_k127_5703806_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 386.0
HKD1_k127_5703806_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 375.0
HKD1_k127_5710273_0 F5/8 type C domain - - - 8.869e-201 649.0
HKD1_k127_5710273_1 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 591.0
HKD1_k127_5710273_10 - - - - 0.000000000000000000000000002737 120.0
HKD1_k127_5710273_11 - - - - 0.00000000002283 72.0
HKD1_k127_5710273_12 Tetratricopeptide repeat - - - 0.000000001766 68.0
HKD1_k127_5710273_14 Trypsin - - - 0.0000001141 63.0
HKD1_k127_5710273_15 - - - - 0.000001487 57.0
HKD1_k127_5710273_2 Type II/IV secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 463.0
HKD1_k127_5710273_3 Belongs to the glycosyl hydrolase 26 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 430.0
HKD1_k127_5710273_4 Type II/IV secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 418.0
HKD1_k127_5710273_5 SigmaW regulon antibacterial - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 407.0
HKD1_k127_5710273_6 cAMP biosynthetic process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 433.0
HKD1_k127_5710273_7 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001036 305.0
HKD1_k127_5710273_8 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000381 192.0
HKD1_k127_5710273_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000002816 139.0
HKD1_k127_5845468_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.056e-271 863.0
HKD1_k127_5845468_1 PFAM Carbamoyltransferase K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 613.0
HKD1_k127_5845468_10 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000006196 173.0
HKD1_k127_5845468_11 - - - - 0.00000000000000000000000000000000000004482 159.0
HKD1_k127_5845468_12 transferase activity, transferring glycosyl groups K16698 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000005831 143.0
HKD1_k127_5845468_13 Glycosyl transferases group 1 - - - 0.000000000000000000000000003039 127.0
HKD1_k127_5845468_14 export protein K01991 - - 0.000000000000000000000000003864 123.0
HKD1_k127_5845468_15 O-Antigen ligase K02847 - - 0.000000000000000000000001096 119.0
HKD1_k127_5845468_16 Glycosyl transferases group 1 - - - 0.00000000000000001378 95.0
HKD1_k127_5845468_17 Glycosyl transferase - - - 0.0000000000003284 81.0
HKD1_k127_5845468_18 lipolytic protein G-D-S-L family - - - 0.000000000001688 79.0
HKD1_k127_5845468_2 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 355.0
HKD1_k127_5845468_20 luxR family - - - 0.000000006555 66.0
HKD1_k127_5845468_21 - - - - 0.000002956 60.0
HKD1_k127_5845468_22 Polysaccharide biosynthesis protein - - - 0.00006601 55.0
HKD1_k127_5845468_3 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 359.0
HKD1_k127_5845468_4 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 297.0
HKD1_k127_5845468_5 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001339 283.0
HKD1_k127_5845468_6 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000005367 261.0
HKD1_k127_5845468_7 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001078 249.0
HKD1_k127_5845468_8 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000002877 209.0
HKD1_k127_5845468_9 peptidyl-tyrosine sulfation K03217,K06872 - - 0.0000000000000000000000000000000000000000000000002704 198.0
HKD1_k127_5891275_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 9.953e-210 659.0
HKD1_k127_5891275_1 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 455.0
HKD1_k127_5891275_10 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000002314 124.0
HKD1_k127_5891275_11 Protein of unknown function (DUF3108) - - - 0.00000000000002087 83.0
HKD1_k127_5891275_12 molecular chaperone K03686 - - 0.00000000000005899 82.0
HKD1_k127_5891275_13 DALR_2 K01883 - 6.1.1.16 0.0000000003234 61.0
HKD1_k127_5891275_14 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000003275 70.0
HKD1_k127_5891275_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 456.0
HKD1_k127_5891275_3 Ion transport 2 domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001298 259.0
HKD1_k127_5891275_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000009551 238.0
HKD1_k127_5891275_5 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000002943 198.0
HKD1_k127_5891275_6 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000006949 186.0
HKD1_k127_5891275_7 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000008532 168.0
HKD1_k127_5891275_8 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000001395 158.0
HKD1_k127_5891275_9 Polysaccharide biosynthesis protein K12454 - 5.1.3.10 0.0000000000000000000000000001527 125.0
HKD1_k127_6065601_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 376.0
HKD1_k127_6129643_0 formate dehydrogenase, alpha subunit K00123,K00370,K08356 - 1.17.1.9,1.20.2.1,1.20.9.1,1.7.5.1 0.0 1241.0
HKD1_k127_6129643_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1095.0
HKD1_k127_6129643_10 NADH dehydrogenase K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 330.0
HKD1_k127_6129643_11 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 310.0
HKD1_k127_6129643_12 polysaccharide deacetylase K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 293.0
HKD1_k127_6129643_13 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006555 267.0
HKD1_k127_6129643_14 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007792 260.0
HKD1_k127_6129643_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009195 252.0
HKD1_k127_6129643_16 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007416 256.0
HKD1_k127_6129643_17 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000001412 224.0
HKD1_k127_6129643_18 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000001899 198.0
HKD1_k127_6129643_19 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000001104 194.0
HKD1_k127_6129643_2 Polysulphide reductase, NrfD - - - 3.561e-201 636.0
HKD1_k127_6129643_20 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000003462 173.0
HKD1_k127_6129643_21 Hydrogenase 4 membrane K12140 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000564 165.0
HKD1_k127_6129643_22 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000003174 142.0
HKD1_k127_6129643_23 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000001652 146.0
HKD1_k127_6129643_24 - - - - 0.0000000000000000000000000002467 116.0
HKD1_k127_6129643_25 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.0000000000000000000000004082 111.0
HKD1_k127_6129643_26 - - - - 0.00000000004905 70.0
HKD1_k127_6129643_27 WD40-like Beta Propeller Repeat - - - 0.000000006512 61.0
HKD1_k127_6129643_28 cAMP biosynthetic process - - - 0.000000008757 61.0
HKD1_k127_6129643_3 Proton-conducting membrane transporter K12137,K15828 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 621.0
HKD1_k127_6129643_30 Matrixin K06974 - - 0.0000002746 53.0
HKD1_k127_6129643_31 Protein kinase domain K12132 - 2.7.11.1 0.0000007628 57.0
HKD1_k127_6129643_32 - - - - 0.0008684 44.0
HKD1_k127_6129643_4 NADH dehydrogenase (ubiquinone) activity K14089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 532.0
HKD1_k127_6129643_5 Voltage gated chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 393.0
HKD1_k127_6129643_6 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 381.0
HKD1_k127_6129643_7 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 385.0
HKD1_k127_6129643_8 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 393.0
HKD1_k127_6129643_9 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 345.0
HKD1_k127_6160158_0 HTH-like domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 370.0
HKD1_k127_6160158_1 RHS Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000003672 246.0
HKD1_k127_6160158_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000009195 149.0
HKD1_k127_6160158_4 - - - - 0.000000000000000000000000005763 117.0
HKD1_k127_6160158_6 Protein of unknown function (DUF2938) - - - 0.000000000000000002551 89.0
HKD1_k127_6160158_7 - - - - 0.000000001047 66.0
HKD1_k127_6160158_8 - - - - 0.000000002674 60.0
HKD1_k127_6165362_0 Domain of unknown function (DUF4118) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 433.0
HKD1_k127_6165362_1 Wzt C-terminal domain K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 398.0
HKD1_k127_6165362_10 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000001139 221.0
HKD1_k127_6165362_12 Esterase-like activity of phytase K03929 - - 0.00000000000000000000000000000000000000000000000000004924 215.0
HKD1_k127_6165362_13 hydrolase of the alpha beta K07018 - - 0.000000000000000000000000000000000000000000000000002443 190.0
HKD1_k127_6165362_14 PFAM glycosyl transferase family 39 K14340 - - 0.00000000000000000000000000000000000000000000000001645 201.0
HKD1_k127_6165362_15 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.0000000000000000000000000000000000000001872 165.0
HKD1_k127_6165362_17 phosphorelay signal transduction system K03776,K14987 - - 0.00000000000000000000000000005397 136.0
HKD1_k127_6165362_18 Methyltransferase domain - - - 0.000000000000000000000001844 110.0
HKD1_k127_6165362_19 Methyltransferase domain - - - 0.000000000000000000000152 113.0
HKD1_k127_6165362_2 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 344.0
HKD1_k127_6165362_20 Methyltransferase domain - - - 0.000000000000000000001511 111.0
HKD1_k127_6165362_21 Transposase - - - 0.000000000000009145 76.0
HKD1_k127_6165362_22 Methyltransferase small domain - - - 0.00000000000001153 89.0
HKD1_k127_6165362_23 Glycogen debranching enzyme K00568 - 2.1.1.222,2.1.1.64 0.00000000005321 74.0
HKD1_k127_6165362_24 ubiE/COQ5 methyltransferase family - - - 0.0000000001606 73.0
HKD1_k127_6165362_25 PFAM Transposase IS200 like K07491 - - 0.00007475 49.0
HKD1_k127_6165362_26 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564 3.1.3.48 0.0001997 51.0
HKD1_k127_6165362_27 Conserved repeat domain - - - 0.0003749 55.0
HKD1_k127_6165362_3 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 322.0
HKD1_k127_6165362_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 311.0
HKD1_k127_6165362_5 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 335.0
HKD1_k127_6165362_6 pyrroloquinoline quinone binding K12287 - - 0.00000000000000000000000000000000000000000000000000000000000000000164 259.0
HKD1_k127_6165362_7 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000006674 244.0
HKD1_k127_6165362_8 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000005315 244.0
HKD1_k127_6165362_9 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000305 236.0
HKD1_k127_6176771_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0 1620.0
HKD1_k127_6176771_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 7.581e-314 971.0
HKD1_k127_6176771_10 PFAM peptidase - - - 2.351e-203 647.0
HKD1_k127_6176771_11 TROVE domain - - - 8.643e-203 643.0
HKD1_k127_6176771_12 Zinc-binding dehydrogenase K00008,K00148,K18369 - 1.1.1.14,1.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 586.0
HKD1_k127_6176771_13 UPF0210 protein K09157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 575.0
HKD1_k127_6176771_14 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 576.0
HKD1_k127_6176771_15 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 572.0
HKD1_k127_6176771_16 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 565.0
HKD1_k127_6176771_17 family UPF0027 K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 518.0
HKD1_k127_6176771_18 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 533.0
HKD1_k127_6176771_19 Pectinesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 512.0
HKD1_k127_6176771_2 ribosome binding - - - 4.022e-307 969.0
HKD1_k127_6176771_20 Aldehyde - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 450.0
HKD1_k127_6176771_21 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 464.0
HKD1_k127_6176771_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 387.0
HKD1_k127_6176771_23 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 356.0
HKD1_k127_6176771_24 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 340.0
HKD1_k127_6176771_25 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 343.0
HKD1_k127_6176771_26 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 317.0
HKD1_k127_6176771_27 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 292.0
HKD1_k127_6176771_28 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002983 298.0
HKD1_k127_6176771_29 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002424 290.0
HKD1_k127_6176771_3 ATPase involved in DNA repair K13924 - 2.1.1.80,3.1.1.61 7.266e-297 948.0
HKD1_k127_6176771_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004288 282.0
HKD1_k127_6176771_31 Flavin containing amine oxidoreductase K00274,K21639 - 1.4.3.25,1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001087 284.0
HKD1_k127_6176771_32 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 232.0
HKD1_k127_6176771_33 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000001291 222.0
HKD1_k127_6176771_34 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000003087 220.0
HKD1_k127_6176771_35 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000287 207.0
HKD1_k127_6176771_36 Bacterial Ig-like domain (group 3) - - - 0.000000000000000000000000000000000000000000000000000764 207.0
HKD1_k127_6176771_37 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000001983 188.0
HKD1_k127_6176771_38 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.000000000000000000000000000000000000000000000000005263 188.0
HKD1_k127_6176771_39 WD40 domain protein beta Propeller - - - 0.0000000000000000000000000000000000000000000000003916 197.0
HKD1_k127_6176771_4 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 1.384e-290 918.0
HKD1_k127_6176771_40 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000000000008037 164.0
HKD1_k127_6176771_41 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000002859 161.0
HKD1_k127_6176771_42 - - - - 0.0000000000000000000000000000000000000003639 156.0
HKD1_k127_6176771_43 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000006683 149.0
HKD1_k127_6176771_44 Psort location Cytoplasmic, score K09707 - - 0.00000000000000000000000000000000000002424 148.0
HKD1_k127_6176771_45 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000005553 152.0
HKD1_k127_6176771_46 BMC - - - 0.0000000000000000000000000000000000001437 145.0
HKD1_k127_6176771_47 Y_Y_Y domain - - - 0.0000000000000000000000000000001474 145.0
HKD1_k127_6176771_48 - - - - 0.0000000000000000000000000000005391 126.0
HKD1_k127_6176771_49 BMC - - - 0.000000000000000000000000000001886 123.0
HKD1_k127_6176771_5 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 5.451e-256 808.0
HKD1_k127_6176771_50 PFAM HNH endonuclease - - - 0.0000000000000000000000000000618 127.0
HKD1_k127_6176771_51 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000000000008767 115.0
HKD1_k127_6176771_52 glyoxalase III activity - - - 0.000000000000000000000000001343 119.0
HKD1_k127_6176771_53 Phage integrase family - - - 0.000000000000000000000000002472 115.0
HKD1_k127_6176771_54 response regulator K02282 - - 0.000000000000000000000000004863 113.0
HKD1_k127_6176771_55 - - - - 0.0000000000000000000000001132 110.0
HKD1_k127_6176771_56 PFAM von Willebrand factor type A - - - 0.00000000000000000000004013 114.0
HKD1_k127_6176771_57 DNA-binding transcription factor activity - - - 0.00000000000000000000006465 103.0
HKD1_k127_6176771_58 - - - - 0.000000000000000000006928 96.0
HKD1_k127_6176771_59 aspartic-type endopeptidase activity K06399 - 3.4.21.116 0.00000000000000000001917 102.0
HKD1_k127_6176771_6 Histidine kinase K02480,K07683 - 2.7.13.3 8.596e-221 718.0
HKD1_k127_6176771_60 Belongs to the UPF0237 family K07166 - - 0.00000000000000000009145 96.0
HKD1_k127_6176771_61 PFAM MerR family regulatory protein K22491 - - 0.0000000000000006154 88.0
HKD1_k127_6176771_62 Belongs to the universal stress protein A family - - - 0.000000000000001889 87.0
HKD1_k127_6176771_63 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000004005 82.0
HKD1_k127_6176771_64 - - - - 0.000000000000004717 78.0
HKD1_k127_6176771_65 Belongs to the 'phage' integrase family - - - 0.000000000000007466 78.0
HKD1_k127_6176771_66 Helix-turn-helix domain - - - 0.00000000000004362 79.0
HKD1_k127_6176771_67 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000001533 62.0
HKD1_k127_6176771_68 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000001753 64.0
HKD1_k127_6176771_69 - - - - 0.0000000004882 72.0
HKD1_k127_6176771_7 PFAM NAD-dependent epimerase dehydratase - - - 9.99e-214 675.0
HKD1_k127_6176771_70 - - - - 0.000000006618 68.0
HKD1_k127_6176771_72 PIN domain - - - 0.0000003262 52.0
HKD1_k127_6176771_73 Polysaccharide biosynthesis/export protein K01991 - - 0.0000004007 62.0
HKD1_k127_6176771_74 - - - - 0.000002953 59.0
HKD1_k127_6176771_75 peptidyl-tyrosine sulfation - - - 0.000003779 59.0
HKD1_k127_6176771_76 Transcription factor zinc-finger K09981 - - 0.000005122 53.0
HKD1_k127_6176771_77 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0001754 45.0
HKD1_k127_6176771_78 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0003676 45.0
HKD1_k127_6176771_8 - - - - 5.797e-208 661.0
HKD1_k127_6176771_9 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.083e-204 647.0
HKD1_k127_6194406_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 8.121e-320 996.0
HKD1_k127_6194406_1 Serine dehydratase beta chain - - - 1.324e-281 872.0
HKD1_k127_6194406_2 secondary active sulfate transmembrane transporter activity K03321 - - 9.13e-237 743.0
HKD1_k127_6194406_3 protein secretion K15125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 387.0
HKD1_k127_6194406_4 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 321.0
HKD1_k127_6194406_5 Ion channel - - - 0.00000000000000000000000000000000000002918 147.0
HKD1_k127_6194406_6 - - - - 0.0000000000000000000000000015 122.0
HKD1_k127_6194406_7 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.000000000000000000000832 98.0
HKD1_k127_6194995_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.378e-272 860.0
HKD1_k127_6194995_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 512.0
HKD1_k127_6194995_10 Psort location Cytoplasmic, score K00945,K01812,K16139 - 2.7.4.25,5.3.1.12 0.0000000000000000000000000000000000000007505 157.0
HKD1_k127_6194995_11 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000008735 102.0
HKD1_k127_6194995_14 Transposase K07491 - - 0.0000000000002344 70.0
HKD1_k127_6194995_2 protease with the C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 494.0
HKD1_k127_6194995_3 PFAM alpha beta hydrolase K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 457.0
HKD1_k127_6194995_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 335.0
HKD1_k127_6194995_5 Major Facilitator Superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 299.0
HKD1_k127_6194995_6 Popeye protein conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000006305 241.0
HKD1_k127_6194995_7 Esterase - - - 0.0000000000000000000000000000000000000000000001228 181.0
HKD1_k127_6194995_8 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.0000000000000000000000000000000000000000000003007 168.0
HKD1_k127_6194995_9 Cupin domain - - - 0.0000000000000000000000000000000000000000006934 161.0
HKD1_k127_6195362_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 1.1e-302 948.0
HKD1_k127_6195362_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 564.0
HKD1_k127_6195362_10 Belongs to the BshC family K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 309.0
HKD1_k127_6195362_11 Serine aminopeptidase, S33 K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002111 288.0
HKD1_k127_6195362_12 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002344 276.0
HKD1_k127_6195362_13 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000002506 252.0
HKD1_k127_6195362_14 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000007048 228.0
HKD1_k127_6195362_15 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000896 224.0
HKD1_k127_6195362_16 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000001138 237.0
HKD1_k127_6195362_17 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000007177 191.0
HKD1_k127_6195362_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000771 185.0
HKD1_k127_6195362_19 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000001672 176.0
HKD1_k127_6195362_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 541.0
HKD1_k127_6195362_20 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000001211 178.0
HKD1_k127_6195362_21 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000002782 188.0
HKD1_k127_6195362_22 DSBA-like thioredoxin domain K21990 - - 0.00000000000000000000000000000004893 134.0
HKD1_k127_6195362_23 PFAM HD domain - - - 0.0000000000000000000000000000001678 131.0
HKD1_k127_6195362_24 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000006332 130.0
HKD1_k127_6195362_25 Biotin-requiring enzyme - - - 0.0000000000000000000000000000685 121.0
HKD1_k127_6195362_26 Thioredoxin-like domain - - - 0.0000000000000000000000001401 111.0
HKD1_k127_6195362_27 PFAM Surface antigen variable number K07277 - - 0.0000000000000000000000002392 120.0
HKD1_k127_6195362_28 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000001016 86.0
HKD1_k127_6195362_29 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000001261 74.0
HKD1_k127_6195362_3 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 514.0
HKD1_k127_6195362_30 - - - - 0.000000000001109 71.0
HKD1_k127_6195362_31 Periplasmic protein thiol disulfide oxidoreductase, DsbE subfamily - - - 0.00000001183 63.0
HKD1_k127_6195362_32 - - - - 0.000001907 53.0
HKD1_k127_6195362_34 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.000003583 49.0
HKD1_k127_6195362_35 Protein of unknown function (DUF721) - - - 0.000006756 54.0
HKD1_k127_6195362_4 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 438.0
HKD1_k127_6195362_5 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 342.0
HKD1_k127_6195362_6 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 332.0
HKD1_k127_6195362_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 320.0
HKD1_k127_6195362_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 316.0
HKD1_k127_6195362_9 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 309.0
HKD1_k127_6220777_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1595.0
HKD1_k127_6220777_1 Sigma-70 region 2 K03088 - - 6.208e-222 692.0
HKD1_k127_6220777_2 Phospholipase D. Active site motifs. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 460.0
HKD1_k127_6220777_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 393.0
HKD1_k127_6220777_4 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001521 281.0
HKD1_k127_6220777_5 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000679 269.0
HKD1_k127_6220777_6 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.00000000000000000000000000000000000000000000000000000000000000001603 234.0
HKD1_k127_6220777_7 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000002974 236.0
HKD1_k127_6220777_8 - - - - 0.0000000000000000002917 93.0
HKD1_k127_6237578_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 422.0
HKD1_k127_6256235_0 PFAM Glycoside hydrolase, family 2, TIM barrel K01190 - 3.2.1.23 0.0 1011.0
HKD1_k127_6256235_1 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 1.269e-287 900.0
HKD1_k127_6256235_10 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 329.0
HKD1_k127_6256235_11 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.000000000000000000000000000000000000000000000000002336 185.0
HKD1_k127_6256235_12 - - - - 0.00000000000000000000000000000001607 134.0
HKD1_k127_6256235_13 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000005046 123.0
HKD1_k127_6256235_14 epimerase - - - 0.0000000000008206 70.0
HKD1_k127_6256235_2 beta-galactosidase activity K01190 - 3.2.1.23 1.183e-276 876.0
HKD1_k127_6256235_3 Belongs to the glycosyl hydrolase 2 family - - - 6.107e-258 831.0
HKD1_k127_6256235_4 F5 8 type C domain protein K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 608.0
HKD1_k127_6256235_5 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 568.0
HKD1_k127_6256235_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 500.0
HKD1_k127_6256235_7 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 448.0
HKD1_k127_6256235_8 arabinan catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 404.0
HKD1_k127_6256235_9 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 352.0
HKD1_k127_627310_0 PFAM type II secretion system protein E K02283,K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 553.0
HKD1_k127_627310_1 PFAM type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000008154 184.0
HKD1_k127_627310_2 Type II secretion system K12510 - - 0.000000000000000000000000000000000000000000000883 180.0
HKD1_k127_627310_3 Response regulator, receiver K02282 - - 0.0000000000000000000000000000000000000000001671 174.0
HKD1_k127_627310_4 TadE-like protein - - - 0.00000000000001763 79.0
HKD1_k127_6327007_0 Vitamin B12 dependent methionine synthase, activation domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1412.0
HKD1_k127_6327007_1 Male sterility protein K01897 - 6.2.1.3 0.0 1281.0
HKD1_k127_6327007_10 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 318.0
HKD1_k127_6327007_11 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 311.0
HKD1_k127_6327007_12 epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 300.0
HKD1_k127_6327007_13 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007198 284.0
HKD1_k127_6327007_14 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001355 256.0
HKD1_k127_6327007_15 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001329 254.0
HKD1_k127_6327007_16 5'-nucleotidase, lipoprotein e(P4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000004415 235.0
HKD1_k127_6327007_17 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000007902 246.0
HKD1_k127_6327007_18 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000001593 229.0
HKD1_k127_6327007_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000313 225.0
HKD1_k127_6327007_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 1.887e-300 942.0
HKD1_k127_6327007_20 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000001426 224.0
HKD1_k127_6327007_21 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000002167 223.0
HKD1_k127_6327007_22 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000001963 201.0
HKD1_k127_6327007_23 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000001789 192.0
HKD1_k127_6327007_24 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000139 173.0
HKD1_k127_6327007_25 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000009715 164.0
HKD1_k127_6327007_26 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000003714 148.0
HKD1_k127_6327007_27 Transport permease protein K01992 - - 0.00000000000000000000000000000000000004464 153.0
HKD1_k127_6327007_28 - - - - 0.0000000000000000000000000000000000001252 149.0
HKD1_k127_6327007_29 Polyketide cyclase / dehydrase and lipid transport K09386 - - 0.0000000000000000000000000000000000008674 144.0
HKD1_k127_6327007_3 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 1.011e-288 915.0
HKD1_k127_6327007_30 Tetratricopeptide repeat - - - 0.0000000000000000000000000000008401 132.0
HKD1_k127_6327007_31 Trypsin-like peptidase domain - - - 0.000000000000000000000000000003318 128.0
HKD1_k127_6327007_32 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000001648 119.0
HKD1_k127_6327007_34 Bacterial DNA-binding protein K03530 - - 0.00000000000000000000003275 102.0
HKD1_k127_6327007_35 von Willebrand factor, type A - - - 0.000000000000000000001591 106.0
HKD1_k127_6327007_36 Nuclease (SNase domain protein) - - - 0.00000000000000003072 94.0
HKD1_k127_6327007_37 - - - - 0.00000000000000003107 93.0
HKD1_k127_6327007_38 Roadblock/LC7 domain - - - 0.000000000000001501 81.0
HKD1_k127_6327007_39 Insulinase (Peptidase family M16) - - - 0.000000000001235 80.0
HKD1_k127_6327007_4 Peptidase M14, carboxypeptidase A - - - 4.778e-277 883.0
HKD1_k127_6327007_40 Ankyrin repeat - - - 0.000000000007915 72.0
HKD1_k127_6327007_42 Gram-negative bacterial TonB protein C-terminal - - - 0.000000002956 70.0
HKD1_k127_6327007_43 PFAM Pilus assembly protein PilO K02664 - - 0.000001647 58.0
HKD1_k127_6327007_5 Domain of unknown function (DUF2088) - - - 2.857e-225 709.0
HKD1_k127_6327007_6 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 440.0
HKD1_k127_6327007_7 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 346.0
HKD1_k127_6327007_8 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 338.0
HKD1_k127_6327007_9 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 320.0
HKD1_k127_6327147_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0 1015.0
HKD1_k127_6327147_1 Asparagine synthase K01953 - 6.3.5.4 7.355e-240 756.0
HKD1_k127_6327147_10 RmlD substrate binding domain K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 437.0
HKD1_k127_6327147_11 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 436.0
HKD1_k127_6327147_12 UDP-N-acetylglucosamine 2-epimerase K01791,K13019 - 5.1.3.14,5.1.3.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 430.0
HKD1_k127_6327147_13 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 394.0
HKD1_k127_6327147_14 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 367.0
HKD1_k127_6327147_15 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 367.0
HKD1_k127_6327147_16 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 351.0
HKD1_k127_6327147_17 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 334.0
HKD1_k127_6327147_18 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 325.0
HKD1_k127_6327147_19 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 328.0
HKD1_k127_6327147_2 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 548.0
HKD1_k127_6327147_20 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 299.0
HKD1_k127_6327147_21 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 301.0
HKD1_k127_6327147_22 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 311.0
HKD1_k127_6327147_23 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000001611 231.0
HKD1_k127_6327147_24 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000001166 218.0
HKD1_k127_6327147_25 - - - - 0.00000000000000000000000000000000000000000000000000000001652 200.0
HKD1_k127_6327147_26 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000001697 207.0
HKD1_k127_6327147_27 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000000000002002 202.0
HKD1_k127_6327147_28 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus - - - 0.00000000000000000000000000000000000000000000000000002417 198.0
HKD1_k127_6327147_29 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000001142 200.0
HKD1_k127_6327147_3 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 533.0
HKD1_k127_6327147_30 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000381 199.0
HKD1_k127_6327147_31 Formyl transferase K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000008962 193.0
HKD1_k127_6327147_32 - - - - 0.000000000000000000000000000000000000000000000000009483 189.0
HKD1_k127_6327147_33 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000001188 163.0
HKD1_k127_6327147_34 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.00000000000000000000000000000000000000005799 153.0
HKD1_k127_6327147_35 GDP-mannose 4,6 dehydratase K08678 - 4.1.1.35 0.00000000000000000000000000000000000004177 147.0
HKD1_k127_6327147_36 lipolytic protein G-D-S-L family K01186 - 3.2.1.18 0.0000000000000000000000000000000002505 141.0
HKD1_k127_6327147_37 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000006873 139.0
HKD1_k127_6327147_38 PFAM Methyltransferase domain - - - 0.00000000000000000000000000002791 126.0
HKD1_k127_6327147_39 oxidoreductase - - - 0.000000000000000000000000005948 123.0
HKD1_k127_6327147_4 PFAM NAD-dependent epimerase dehydratase K01710,K01784,K02473,K08678 - 4.1.1.35,4.2.1.46,5.1.3.2,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 490.0
HKD1_k127_6327147_40 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000002943 100.0
HKD1_k127_6327147_41 Methyltransferase domain - - - 0.00000000000000002378 91.0
HKD1_k127_6327147_42 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000001036 84.0
HKD1_k127_6327147_43 Methionine biosynthesis protein MetW - - - 0.000000003534 68.0
HKD1_k127_6327147_44 PFAM Methyltransferase type 11 - - - 0.00000000442 66.0
HKD1_k127_6327147_45 GDP-mannose 4,6 dehydratase K08678 - 4.1.1.35 0.0003267 46.0
HKD1_k127_6327147_5 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 486.0
HKD1_k127_6327147_6 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 479.0
HKD1_k127_6327147_7 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 476.0
HKD1_k127_6327147_8 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 468.0
HKD1_k127_6327147_9 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 444.0
HKD1_k127_6363478_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1328.0
HKD1_k127_6363478_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 331.0
HKD1_k127_6363478_2 PFAM Isochorismatase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000003839 213.0
HKD1_k127_6363478_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000003153 173.0
HKD1_k127_6363478_4 PFAM S23 ribosomal protein - - - 0.0000000003967 63.0
HKD1_k127_6363478_5 23S rRNA-intervening sequence protein - - - 0.000000006063 62.0
HKD1_k127_6363478_6 Transposase IS200 like - - - 0.0003341 44.0
HKD1_k127_6392760_0 cellulose binding - - - 8.15e-222 692.0
HKD1_k127_6392760_1 Glycosyltransferase like family 2 K07011,K20444 - - 3.143e-197 654.0
HKD1_k127_6392760_10 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002794 244.0
HKD1_k127_6392760_11 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000001621 207.0
HKD1_k127_6392760_12 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000003486 179.0
HKD1_k127_6392760_13 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000000008316 151.0
HKD1_k127_6392760_14 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000495 142.0
HKD1_k127_6392760_15 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000001079 138.0
HKD1_k127_6392760_16 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000127 94.0
HKD1_k127_6392760_17 - - - - 0.000000000000000265 83.0
HKD1_k127_6392760_19 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000667 66.0
HKD1_k127_6392760_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 533.0
HKD1_k127_6392760_20 ORF located using Blastx - - - 0.000000003321 59.0
HKD1_k127_6392760_21 - - - - 0.00000002535 55.0
HKD1_k127_6392760_22 - - - - 0.00000002863 58.0
HKD1_k127_6392760_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 443.0
HKD1_k127_6392760_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 390.0
HKD1_k127_6392760_5 Calcium Proton K07300 GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035725,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 382.0
HKD1_k127_6392760_6 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 319.0
HKD1_k127_6392760_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 310.0
HKD1_k127_6392760_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006712 270.0
HKD1_k127_6392760_9 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003651 245.0
HKD1_k127_6395855_0 PFAM Protein kinase domain K01768,K07216 - 4.6.1.1 9.308e-265 880.0
HKD1_k127_6395855_1 IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 577.0
HKD1_k127_6395855_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 503.0
HKD1_k127_6395855_3 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007381 282.0
HKD1_k127_6395855_4 OprF membrane domain K07275 - - 0.0000000000000000000000000000000000000000000000000004026 192.0
HKD1_k127_6395855_5 hmm pf01609 K07481 - - 0.00000000000000000000000000000000000000000000007142 170.0
HKD1_k127_6395855_6 Phage integrase family - - - 0.000000000000000000000000000000000000002838 149.0
HKD1_k127_6412687_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 7.983e-306 976.0
HKD1_k127_6412687_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 3.577e-207 659.0
HKD1_k127_6412687_10 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 385.0
HKD1_k127_6412687_11 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 380.0
HKD1_k127_6412687_12 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 366.0
HKD1_k127_6412687_13 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 371.0
HKD1_k127_6412687_14 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 343.0
HKD1_k127_6412687_15 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 320.0
HKD1_k127_6412687_16 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 297.0
HKD1_k127_6412687_17 Permease, YjgP YjgQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 307.0
HKD1_k127_6412687_18 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006313 284.0
HKD1_k127_6412687_19 Methyltransferase domain K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000004107 250.0
HKD1_k127_6412687_2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 2.498e-201 633.0
HKD1_k127_6412687_20 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000001405 244.0
HKD1_k127_6412687_21 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000001966 238.0
HKD1_k127_6412687_22 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001075 215.0
HKD1_k127_6412687_23 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000009165 215.0
HKD1_k127_6412687_24 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000001001 226.0
HKD1_k127_6412687_26 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000002084 202.0
HKD1_k127_6412687_27 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000003236 177.0
HKD1_k127_6412687_28 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000003497 186.0
HKD1_k127_6412687_29 Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000642 179.0
HKD1_k127_6412687_3 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 591.0
HKD1_k127_6412687_30 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000787 180.0
HKD1_k127_6412687_31 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000002145 162.0
HKD1_k127_6412687_32 Transposase IS200 like - - - 0.00000000000000000000000000000000000000158 150.0
HKD1_k127_6412687_33 L-threonylcarbamoyladenylate synthase K07566 - 2.7.7.87 0.000000000000000000000000000000000000001981 154.0
HKD1_k127_6412687_34 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000005251 154.0
HKD1_k127_6412687_35 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000009324 146.0
HKD1_k127_6412687_36 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000002113 151.0
HKD1_k127_6412687_37 Universal stress protein family - - - 0.000000000000000000000000000000000001169 151.0
HKD1_k127_6412687_38 PFAM aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000007787 150.0
HKD1_k127_6412687_39 von Willebrand factor, type A - - - 0.000000000000000000000000000000002 141.0
HKD1_k127_6412687_4 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 596.0
HKD1_k127_6412687_40 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000000003572 130.0
HKD1_k127_6412687_41 - - - - 0.0000000000000000000000000000004436 131.0
HKD1_k127_6412687_42 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000001441 124.0
HKD1_k127_6412687_43 Protein of unknown function (DUF3303) - - - 0.0000000000000000000000000004455 116.0
HKD1_k127_6412687_44 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000004553 114.0
HKD1_k127_6412687_45 - - - - 0.00000000000000000000000007406 111.0
HKD1_k127_6412687_46 PQQ-like domain - - - 0.0000000000000000000002136 110.0
HKD1_k127_6412687_47 Glycoprotease family K14742 - - 0.0000000000000000000003367 106.0
HKD1_k127_6412687_48 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000003328 101.0
HKD1_k127_6412687_49 Domain of unknown function (DUF4437) - - - 0.0000000000000000004909 98.0
HKD1_k127_6412687_5 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 582.0
HKD1_k127_6412687_50 - - - - 0.0000000000000000009492 91.0
HKD1_k127_6412687_51 Caspase domain - - - 0.000000000000000001217 96.0
HKD1_k127_6412687_54 Protein of unknown function (DUF465) - - - 0.000000002913 62.0
HKD1_k127_6412687_58 - - - - 0.00013 51.0
HKD1_k127_6412687_59 - - - - 0.0001409 46.0
HKD1_k127_6412687_6 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 554.0
HKD1_k127_6412687_60 NB-ARC domain - - - 0.0001679 54.0
HKD1_k127_6412687_7 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 445.0
HKD1_k127_6412687_8 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 420.0
HKD1_k127_6412687_9 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 387.0
HKD1_k127_6419629_0 Peptidase M14, carboxypeptidase A - - - 0.0 1389.0
HKD1_k127_6419629_1 cellulose binding - - - 5.48e-301 955.0
HKD1_k127_6419629_10 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 304.0
HKD1_k127_6419629_11 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 295.0
HKD1_k127_6419629_12 PFAM monooxygenase FAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 296.0
HKD1_k127_6419629_13 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007537 271.0
HKD1_k127_6419629_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001046 246.0
HKD1_k127_6419629_15 Uracil DNA glycosylase superfamily K01934,K03649 GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.28,6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000002862 240.0
HKD1_k127_6419629_16 Protein tyrosine kinase K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000002834 260.0
HKD1_k127_6419629_17 AAA-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000002483 239.0
HKD1_k127_6419629_18 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000003266 216.0
HKD1_k127_6419629_19 Psort location Cytoplasmic, score K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000007491 180.0
HKD1_k127_6419629_2 Domain of unknown function (DUF5117) - - - 2.237e-285 899.0
HKD1_k127_6419629_20 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000003499 177.0
HKD1_k127_6419629_21 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000008339 149.0
HKD1_k127_6419629_22 - - - - 0.00000000000000000000000000000002335 134.0
HKD1_k127_6419629_23 peptidyl-tyrosine sulfation K03217,K06872 - - 0.0000000000000000000000000000005981 132.0
HKD1_k127_6419629_24 Thioredoxin-like - - - 0.000000000000000000004182 102.0
HKD1_k127_6419629_25 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000003037 104.0
HKD1_k127_6419629_26 3D domain - - - 0.000000000000000003253 92.0
HKD1_k127_6419629_27 - - - - 0.000000002312 59.0
HKD1_k127_6419629_28 Tetratricopeptide repeat - - - 0.000000004646 61.0
HKD1_k127_6419629_29 Tetratricopeptide repeats - - - 0.0001162 56.0
HKD1_k127_6419629_3 Carboxypeptidase regulatory-like domain - - - 5.813e-270 864.0
HKD1_k127_6419629_30 Transposase and inactivated derivatives - - - 0.0006317 43.0
HKD1_k127_6419629_4 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.277e-222 716.0
HKD1_k127_6419629_5 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 585.0
HKD1_k127_6419629_6 glycyl-tRNA aminoacylation K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 528.0
HKD1_k127_6419629_7 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 524.0
HKD1_k127_6419629_8 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 514.0
HKD1_k127_6419629_9 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 308.0
HKD1_k127_6423444_0 aminopeptidase activity K01301 - 3.4.17.21 2.318e-313 975.0
HKD1_k127_6423444_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.374e-299 937.0
HKD1_k127_6423444_10 Transporter-associated region K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 496.0
HKD1_k127_6423444_11 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 511.0
HKD1_k127_6423444_12 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 482.0
HKD1_k127_6423444_13 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 469.0
HKD1_k127_6423444_14 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008172 479.0
HKD1_k127_6423444_15 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 401.0
HKD1_k127_6423444_16 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 388.0
HKD1_k127_6423444_17 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 377.0
HKD1_k127_6423444_18 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 350.0
HKD1_k127_6423444_19 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 346.0
HKD1_k127_6423444_2 Zinc metalloprotease (Elastase) - - - 2.709e-263 831.0
HKD1_k127_6423444_21 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 321.0
HKD1_k127_6423444_22 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 303.0
HKD1_k127_6423444_23 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 297.0
HKD1_k127_6423444_24 Erythromycin esterase K06880 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 303.0
HKD1_k127_6423444_25 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002954 279.0
HKD1_k127_6423444_26 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003731 297.0
HKD1_k127_6423444_27 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001203 279.0
HKD1_k127_6423444_28 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001874 285.0
HKD1_k127_6423444_29 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000005291 260.0
HKD1_k127_6423444_3 Peptidase family M1 domain - - - 8.852e-260 814.0
HKD1_k127_6423444_30 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001773 263.0
HKD1_k127_6423444_31 protein and some similarities with VgrG protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000869 249.0
HKD1_k127_6423444_32 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000005186 244.0
HKD1_k127_6423444_33 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000005514 222.0
HKD1_k127_6423444_34 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000002638 217.0
HKD1_k127_6423444_35 Pilus assembly protein PilX - - - 0.0000000000000000000000000000000000000000000000000000000000006426 241.0
HKD1_k127_6423444_36 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.00000000000000000000000000000000000000000000000000000006938 203.0
HKD1_k127_6423444_37 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000006278 187.0
HKD1_k127_6423444_38 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000001658 194.0
HKD1_k127_6423444_39 CHASE2 - - - 0.000000000000000000000000000000000000000000000002425 197.0
HKD1_k127_6423444_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.19e-255 801.0
HKD1_k127_6423444_40 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000000002905 196.0
HKD1_k127_6423444_41 - - - - 0.00000000000000000000000000000000000000000000001512 176.0
HKD1_k127_6423444_42 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.0000000000000000000000000000000000000000000001068 171.0
HKD1_k127_6423444_43 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000001226 171.0
HKD1_k127_6423444_44 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000001395 178.0
HKD1_k127_6423444_45 Peptidase, M23 family - - - 0.000000000000000000000000000000000000008885 157.0
HKD1_k127_6423444_46 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.00000000000000000000000000000002331 144.0
HKD1_k127_6423444_47 SET domain K07117 - - 0.00000000000000000000000000000009427 129.0
HKD1_k127_6423444_48 Ferredoxin - - - 0.0000000000000000000000000001601 119.0
HKD1_k127_6423444_49 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000000000339 128.0
HKD1_k127_6423444_5 von Willebrand factor, type A K07114 - - 2.843e-200 651.0
HKD1_k127_6423444_50 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000001147 113.0
HKD1_k127_6423444_51 cold-shock protein K03704 - - 0.0000000000000000000000004602 106.0
HKD1_k127_6423444_52 Protein of unknown function (DUF998) - - - 0.0000000000000000000000006401 113.0
HKD1_k127_6423444_53 - - - - 0.000000000000000000000004078 108.0
HKD1_k127_6423444_54 - - - - 0.00000000000000000000001864 109.0
HKD1_k127_6423444_55 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000001302 101.0
HKD1_k127_6423444_56 - - - - 0.00000000000000001789 93.0
HKD1_k127_6423444_57 Hsp20/alpha crystallin family - - - 0.0000000000001992 77.0
HKD1_k127_6423444_58 - - - - 0.000000000007236 75.0
HKD1_k127_6423444_60 SnoaL-like domain - - - 0.000000002269 63.0
HKD1_k127_6423444_61 Pilus assembly protein PilX K02673 - - 0.000000006153 69.0
HKD1_k127_6423444_63 DinB family - - - 0.0000003026 51.0
HKD1_k127_6423444_64 Putative adhesin - - - 0.000001365 59.0
HKD1_k127_6423444_65 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000009042 55.0
HKD1_k127_6423444_67 Putative zinc-finger - - - 0.00002599 55.0
HKD1_k127_6423444_7 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 606.0
HKD1_k127_6423444_8 PFAM magnesium chelatase K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 565.0
HKD1_k127_6423444_9 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 507.0
HKD1_k127_6443543_0 Carboxypeptidase regulatory-like domain - - - 0.0 1034.0
HKD1_k127_6443543_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 512.0
HKD1_k127_6443543_10 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000000000000000000000002245 149.0
HKD1_k127_6443543_11 PFAM MbtH domain protein K05375 - - 0.0000000000000000000000000000000000003195 144.0
HKD1_k127_6443543_12 CHAD domain containing protein - - - 0.00000000000000000000000003777 120.0
HKD1_k127_6443543_13 lipopolysaccharide metabolic process K08309,K19804 - - 0.00000000000000000006548 103.0
HKD1_k127_6443543_14 hydroperoxide reductase activity - - - 0.00000000000000000006566 92.0
HKD1_k127_6443543_15 Transposase IS200 like - - - 0.0000000002233 61.0
HKD1_k127_6443543_17 - - - - 0.0009628 51.0
HKD1_k127_6443543_2 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 477.0
HKD1_k127_6443543_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 424.0
HKD1_k127_6443543_4 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 307.0
HKD1_k127_6443543_5 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 303.0
HKD1_k127_6443543_6 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000001437 258.0
HKD1_k127_6443543_7 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.00000000000000000000000000000000000000000000000002999 186.0
HKD1_k127_6443543_8 Chloramphenicol acetyltransferase K19271 - 2.3.1.28 0.0000000000000000000000000000000000000000000000001603 183.0
HKD1_k127_6443543_9 O-Antigen ligase K02847 - - 0.000000000000000000000000000000000000000005357 173.0
HKD1_k127_6451777_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 5.67e-242 764.0
HKD1_k127_6451777_1 E1-E2 ATPase K12952 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - 7.361e-220 708.0
HKD1_k127_6451777_10 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 455.0
HKD1_k127_6451777_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 432.0
HKD1_k127_6451777_12 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 432.0
HKD1_k127_6451777_13 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 428.0
HKD1_k127_6451777_14 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 384.0
HKD1_k127_6451777_15 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 414.0
HKD1_k127_6451777_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 367.0
HKD1_k127_6451777_17 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 367.0
HKD1_k127_6451777_18 SpoIVB peptidase S55 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 357.0
HKD1_k127_6451777_19 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 339.0
HKD1_k127_6451777_2 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 597.0
HKD1_k127_6451777_20 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 337.0
HKD1_k127_6451777_21 epimerase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 335.0
HKD1_k127_6451777_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 326.0
HKD1_k127_6451777_23 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 320.0
HKD1_k127_6451777_24 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 308.0
HKD1_k127_6451777_25 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 309.0
HKD1_k127_6451777_26 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 311.0
HKD1_k127_6451777_27 PFAM Pyridoxal-dependent decarboxylase conserved domain K01580,K01593,K13745 - 4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 307.0
HKD1_k127_6451777_28 oxidoreductase activity, acting on CH-OH group of donors K13237 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001279 286.0
HKD1_k127_6451777_29 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000001236 267.0
HKD1_k127_6451777_3 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007539 593.0
HKD1_k127_6451777_30 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000143 273.0
HKD1_k127_6451777_31 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009515 272.0
HKD1_k127_6451777_32 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006231 263.0
HKD1_k127_6451777_33 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001114 244.0
HKD1_k127_6451777_34 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000001649 241.0
HKD1_k127_6451777_35 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000007911 232.0
HKD1_k127_6451777_36 Metalloenzyme superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000004983 227.0
HKD1_k127_6451777_37 peptidoglycan biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000144 232.0
HKD1_k127_6451777_38 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000002453 226.0
HKD1_k127_6451777_39 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000005302 237.0
HKD1_k127_6451777_4 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 512.0
HKD1_k127_6451777_40 phosphoserine phosphatase activity K07315,K16928 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000003585 221.0
HKD1_k127_6451777_41 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000005462 198.0
HKD1_k127_6451777_42 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000002258 198.0
HKD1_k127_6451777_43 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000003927 202.0
HKD1_k127_6451777_44 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000001185 197.0
HKD1_k127_6451777_45 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000002065 167.0
HKD1_k127_6451777_46 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000005839 142.0
HKD1_k127_6451777_47 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000006903 134.0
HKD1_k127_6451777_48 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.00000000000000000000000000000004075 131.0
HKD1_k127_6451777_49 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000001363 126.0
HKD1_k127_6451777_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 503.0
HKD1_k127_6451777_50 Lysin motif - - - 0.0000000000000000000000000001101 119.0
HKD1_k127_6451777_51 domain, Protein K07004 - - 0.0000000000000000000000000003082 136.0
HKD1_k127_6451777_52 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000001176 120.0
HKD1_k127_6451777_53 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000002425 119.0
HKD1_k127_6451777_54 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000005763 117.0
HKD1_k127_6451777_55 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000001358 106.0
HKD1_k127_6451777_56 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000001399 106.0
HKD1_k127_6451777_57 retrograde transport, endosome to plasma membrane K21440 GO:0006810,GO:0008150,GO:0016192,GO:0016197,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0098876,GO:1990126 - 0.00000000000000000002167 101.0
HKD1_k127_6451777_58 Dodecin K09165 - - 0.0000000000000000005242 89.0
HKD1_k127_6451777_59 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000007973 100.0
HKD1_k127_6451777_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 509.0
HKD1_k127_6451777_61 NfeD-like C-terminal, partner-binding - - - 0.00000000000000001649 88.0
HKD1_k127_6451777_62 thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000001335 81.0
HKD1_k127_6451777_63 BON domain - - - 0.0000000000000001747 85.0
HKD1_k127_6451777_65 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000008916 91.0
HKD1_k127_6451777_66 Uroporphyrinogen-III synthase K01719,K13542 - 2.1.1.107,4.2.1.75 0.00000000000001511 83.0
HKD1_k127_6451777_67 Thioredoxin-like - - - 0.00000000000007363 79.0
HKD1_k127_6451777_68 - - - - 0.000000000000153 79.0
HKD1_k127_6451777_69 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000001161 80.0
HKD1_k127_6451777_7 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 495.0
HKD1_k127_6451777_70 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.00000000003046 74.0
HKD1_k127_6451777_71 - - - - 0.000000003675 60.0
HKD1_k127_6451777_72 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.00000001059 71.0
HKD1_k127_6451777_73 PFAM Abortive infection protein K07052 - - 0.000000129 61.0
HKD1_k127_6451777_74 protein conserved in cyanobacteria - - - 0.0000004287 56.0
HKD1_k127_6451777_75 PFAM Haemolysin-type calcium-binding repeat - - - 0.0000004923 65.0
HKD1_k127_6451777_77 glycosyl transferase K20444 - - 0.0000958 51.0
HKD1_k127_6451777_78 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0001049 53.0
HKD1_k127_6451777_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 490.0
HKD1_k127_6451777_9 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 489.0
HKD1_k127_6514358_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1019.0
HKD1_k127_6514358_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 3.273e-272 850.0
HKD1_k127_6514358_10 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 410.0
HKD1_k127_6514358_12 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008772 367.0
HKD1_k127_6514358_13 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 330.0
HKD1_k127_6514358_14 Transcriptional regulator K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 338.0
HKD1_k127_6514358_15 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 308.0
HKD1_k127_6514358_16 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004191 268.0
HKD1_k127_6514358_17 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000194 284.0
HKD1_k127_6514358_18 response regulator, receiver K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002683 250.0
HKD1_k127_6514358_19 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006513 254.0
HKD1_k127_6514358_2 NhaP-type Na H and K H antiporters K03316 - - 3.71e-201 654.0
HKD1_k127_6514358_20 Transcriptional regulatory protein, C terminal K07669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004008 246.0
HKD1_k127_6514358_21 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000331 257.0
HKD1_k127_6514358_22 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000002432 186.0
HKD1_k127_6514358_23 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000000000000000000000004561 200.0
HKD1_k127_6514358_24 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000003646 175.0
HKD1_k127_6514358_25 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000002713 162.0
HKD1_k127_6514358_26 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000001028 158.0
HKD1_k127_6514358_27 phosphorelay signal transduction system K02490 - - 0.000000000000000000000000000000000000001167 158.0
HKD1_k127_6514358_28 phosphorelay signal transduction system K02490 - - 0.00000000000000000000000000000000004456 143.0
HKD1_k127_6514358_29 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000009463 92.0
HKD1_k127_6514358_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 574.0
HKD1_k127_6514358_30 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000001526 98.0
HKD1_k127_6514358_31 Calx-beta domain - - - 0.0000000000000000008417 102.0
HKD1_k127_6514358_35 Bacterial regulatory proteins, tetR family - - - 0.000005481 56.0
HKD1_k127_6514358_36 - - - - 0.00003095 56.0
HKD1_k127_6514358_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 476.0
HKD1_k127_6514358_5 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 447.0
HKD1_k127_6514358_6 protein histidine kinase activity K11383 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 445.0
HKD1_k127_6514358_7 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 458.0
HKD1_k127_6514358_8 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 409.0
HKD1_k127_6514358_9 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 452.0
HKD1_k127_6518176_0 Tetratricopeptide repeat - - - 4.49e-238 773.0
HKD1_k127_6518176_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.845e-214 678.0
HKD1_k127_6518176_10 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 420.0
HKD1_k127_6518176_11 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 431.0
HKD1_k127_6518176_12 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 415.0
HKD1_k127_6518176_13 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 421.0
HKD1_k127_6518176_14 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 373.0
HKD1_k127_6518176_15 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 368.0
HKD1_k127_6518176_16 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 370.0
HKD1_k127_6518176_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 329.0
HKD1_k127_6518176_18 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 327.0
HKD1_k127_6518176_19 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 323.0
HKD1_k127_6518176_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 601.0
HKD1_k127_6518176_20 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001337 280.0
HKD1_k127_6518176_21 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007828 277.0
HKD1_k127_6518176_22 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008375 266.0
HKD1_k127_6518176_23 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000002056 263.0
HKD1_k127_6518176_24 enterobactin catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000003474 243.0
HKD1_k127_6518176_25 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000003774 235.0
HKD1_k127_6518176_26 Transglutaminase-like superfamily K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000007603 250.0
HKD1_k127_6518176_27 - - - - 0.000000000000000000000000000000000000000000000000000000002517 220.0
HKD1_k127_6518176_28 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000004164 206.0
HKD1_k127_6518176_29 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000001742 202.0
HKD1_k127_6518176_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 599.0
HKD1_k127_6518176_30 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000001704 207.0
HKD1_k127_6518176_31 TfuA-like protein - - - 0.0000000000000000000000000000000000000000000000000004186 192.0
HKD1_k127_6518176_32 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000006011 194.0
HKD1_k127_6518176_33 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000001061 174.0
HKD1_k127_6518176_34 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000001414 174.0
HKD1_k127_6518176_35 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000008806 184.0
HKD1_k127_6518176_36 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000000002748 144.0
HKD1_k127_6518176_37 PFAM Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000003166 143.0
HKD1_k127_6518176_38 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000009055 134.0
HKD1_k127_6518176_39 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000003359 122.0
HKD1_k127_6518176_4 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 533.0
HKD1_k127_6518176_40 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000003952 113.0
HKD1_k127_6518176_41 - - - - 0.000000000000000000000005582 107.0
HKD1_k127_6518176_42 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000001596 102.0
HKD1_k127_6518176_43 Thioredoxin-like - - - 0.0000000000000000001387 103.0
HKD1_k127_6518176_44 Hep Hag repeat protein - - - 0.00000000000002015 89.0
HKD1_k127_6518176_45 integral membrane protein - - - 0.0000000000001741 78.0
HKD1_k127_6518176_46 ECF sigma factor - - - 0.0000000003601 61.0
HKD1_k127_6518176_47 - - - - 0.00000002288 64.0
HKD1_k127_6518176_49 - - - - 0.00001496 57.0
HKD1_k127_6518176_5 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 509.0
HKD1_k127_6518176_50 arylsulfatase A - - - 0.000748 53.0
HKD1_k127_6518176_6 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 505.0
HKD1_k127_6518176_7 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 484.0
HKD1_k127_6518176_8 PFAM Beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 481.0
HKD1_k127_6518176_9 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 432.0
HKD1_k127_654031_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 8.709e-239 749.0
HKD1_k127_654031_1 oxidoreductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 524.0
HKD1_k127_654031_2 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008437 487.0
HKD1_k127_654031_3 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 316.0
HKD1_k127_654031_4 response regulator K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000001189 232.0
HKD1_k127_654031_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000003762 207.0
HKD1_k127_654031_6 - - - - 0.000000000000000000000000000000000000000000001553 169.0
HKD1_k127_654031_7 Glucose / Sorbosone dehydrogenase - - - 0.00000000000004475 73.0
HKD1_k127_654031_8 Glucose / Sorbosone dehydrogenase - - - 0.000000003282 57.0
HKD1_k127_654031_9 - - - - 0.00002072 49.0
HKD1_k127_6643771_0 Acetyl-coenzyme A synthetase N-terminus - - - 5e-324 1001.0
HKD1_k127_6643771_1 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 457.0
HKD1_k127_6643771_10 - - - - 0.00000000000000000000265 97.0
HKD1_k127_6643771_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000003932 231.0
HKD1_k127_6643771_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000001682 223.0
HKD1_k127_6643771_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000004991 214.0
HKD1_k127_6643771_5 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000008325 171.0
HKD1_k127_6643771_6 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000009256 159.0
HKD1_k127_6643771_7 - - - - 0.000000000000000000000000000000009853 132.0
HKD1_k127_6643771_8 CutA1 divalent ion tolerance protein - - - 0.000000000000000000000000001205 115.0
HKD1_k127_6654798_0 choline dehydrogenase activity - - - 1.221e-268 833.0
HKD1_k127_6654798_1 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 608.0
HKD1_k127_6654798_10 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000001719 183.0
HKD1_k127_6654798_11 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000003027 184.0
HKD1_k127_6654798_12 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000004492 183.0
HKD1_k127_6654798_13 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.00000000000000000000000000000000000000000000002552 185.0
HKD1_k127_6654798_14 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000003675 180.0
HKD1_k127_6654798_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000001706 167.0
HKD1_k127_6654798_16 Haem-degrading - - - 0.00000000000000000000000000000000005659 139.0
HKD1_k127_6654798_17 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.00000000000000000001555 100.0
HKD1_k127_6654798_18 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000000006872 94.0
HKD1_k127_6654798_19 Putative zinc-finger - - - 0.0000001511 60.0
HKD1_k127_6654798_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 468.0
HKD1_k127_6654798_20 Putative zinc-finger - - - 0.000314 48.0
HKD1_k127_6654798_21 Putative zinc-finger - - - 0.0003457 48.0
HKD1_k127_6654798_22 Domain of unknown function (DUF4440) - - - 0.0004444 48.0
HKD1_k127_6654798_3 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 347.0
HKD1_k127_6654798_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 336.0
HKD1_k127_6654798_5 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 333.0
HKD1_k127_6654798_6 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 312.0
HKD1_k127_6654798_7 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 290.0
HKD1_k127_6654798_8 uridine kinase K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000001847 236.0
HKD1_k127_6654798_9 - - - - 0.0000000000000000000000000000000000000000000000000000007899 197.0
HKD1_k127_6694911_0 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.0 1170.0
HKD1_k127_6694911_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 2.297e-308 966.0
HKD1_k127_6694911_10 PFAM Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004063 276.0
HKD1_k127_6694911_11 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000009937 262.0
HKD1_k127_6694911_12 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000003048 242.0
HKD1_k127_6694911_13 RNA polymerase, sigma-24 subunit, ECF subfamily K02405 - - 0.0000000000000000000000000000000000000000000000000000000000003833 216.0
HKD1_k127_6694911_14 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000001674 216.0
HKD1_k127_6694911_16 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000003503 147.0
HKD1_k127_6694911_17 AMP binding K06149 - - 0.00000000000000000000000000001265 124.0
HKD1_k127_6694911_18 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000001765 116.0
HKD1_k127_6694911_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 4.302e-241 756.0
HKD1_k127_6694911_20 Universal stress protein family - - - 0.0000000000000000000000002713 112.0
HKD1_k127_6694911_21 Universal stress protein family - - - 0.0000000000000000000000009756 115.0
HKD1_k127_6694911_22 Hep Hag repeat protein - - - 0.0000000000000000000004805 111.0
HKD1_k127_6694911_23 Glucose Sorbosone dehydrogenase - - - 0.000000000000000000117 103.0
HKD1_k127_6694911_24 - - - - 0.000000000000000006745 89.0
HKD1_k127_6694911_25 Hep Hag repeat protein - - - 0.000000000108 74.0
HKD1_k127_6694911_26 Domain of unknown function (DUF4136) - - - 0.0000000001161 71.0
HKD1_k127_6694911_28 Membrane - - - 0.000000002212 66.0
HKD1_k127_6694911_29 alginic acid biosynthetic process - - - 0.000000006316 68.0
HKD1_k127_6694911_3 serine threonine protein kinase K12132 - 2.7.11.1 1.448e-204 674.0
HKD1_k127_6694911_30 Family of unknown function (DUF5335) - - - 0.000008166 53.0
HKD1_k127_6694911_4 Erythromycin esterase - - - 4.47e-201 636.0
HKD1_k127_6694911_5 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 516.0
HKD1_k127_6694911_6 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 494.0
HKD1_k127_6694911_7 Putative methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 400.0
HKD1_k127_6694911_8 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 346.0
HKD1_k127_6694911_9 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000146 274.0
HKD1_k127_6702024_0 Tricorn protease C1 domain K08676 - - 0.0 1251.0
HKD1_k127_6702024_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 572.0
HKD1_k127_6702024_2 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 308.0
HKD1_k127_6702024_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002599 251.0
HKD1_k127_6754334_0 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 514.0
HKD1_k127_6754334_1 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 395.0
HKD1_k127_6754334_10 von Willebrand factor, type A K07114 - - 0.00004849 55.0
HKD1_k127_6754334_12 - - - - 0.0002804 50.0
HKD1_k127_6754334_2 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002413 292.0
HKD1_k127_6754334_3 Enoyl-(Acyl carrier protein) reductase K00034,K03366 - 1.1.1.304,1.1.1.47,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000259 206.0
HKD1_k127_6754334_4 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000003625 182.0
HKD1_k127_6754334_5 Radical SAM K22227 - - 0.00000000000000000000000000000000000005172 158.0
HKD1_k127_6754334_6 Domain of unknown function (DUF4252) - - - 0.000000000000000000000000000000000007831 143.0
HKD1_k127_6754334_7 Monogalactosyldiacylglycerol (MGDG) synthase K03715 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006643,GO:0006664,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0009058,GO:0009247,GO:0009507,GO:0009526,GO:0009528,GO:0009536,GO:0009657,GO:0009668,GO:0009706,GO:0009790,GO:0009791,GO:0009793,GO:0009941,GO:0009987,GO:0010027,GO:0010154,GO:0016020,GO:0016043,GO:0016740,GO:0016757,GO:0016758,GO:0019866,GO:0022414,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0032501,GO:0032502,GO:0035250,GO:0042170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046467,GO:0046509,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0061024,GO:0061458,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.46 0.0000000000000000000000000000002654 137.0
HKD1_k127_6754334_8 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000002299 134.0
HKD1_k127_6754334_9 domain protein K01179,K12567,K20276,K21449 - 2.7.11.1,3.2.1.4 0.0000000000000000000000000000239 138.0
HKD1_k127_6867708_0 Urocanase Rossmann-like domain K01712 - 4.2.1.49 9.752e-270 839.0
HKD1_k127_6867708_1 3-isopropylmalate dehydratase activity K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 2.668e-223 699.0
HKD1_k127_6867708_10 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 486.0
HKD1_k127_6867708_11 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 482.0
HKD1_k127_6867708_12 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 467.0
HKD1_k127_6867708_13 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 454.0
HKD1_k127_6867708_14 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 406.0
HKD1_k127_6867708_15 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 408.0
HKD1_k127_6867708_16 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 390.0
HKD1_k127_6867708_17 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 374.0
HKD1_k127_6867708_18 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 370.0
HKD1_k127_6867708_19 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 342.0
HKD1_k127_6867708_2 PFAM glycoside hydrolase family 39 - - - 4.419e-205 660.0
HKD1_k127_6867708_20 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 296.0
HKD1_k127_6867708_21 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 309.0
HKD1_k127_6867708_22 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007229 280.0
HKD1_k127_6867708_23 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002902 259.0
HKD1_k127_6867708_24 Enoyl-CoA hydratase/isomerase K01715,K13767 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000001548 233.0
HKD1_k127_6867708_25 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000005407 246.0
HKD1_k127_6867708_26 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000005505 230.0
HKD1_k127_6867708_27 Predicted integral membrane protein (DUF2270) - - - 0.00000000000000000000000000000000000000000000000000000000000001174 229.0
HKD1_k127_6867708_28 - - - - 0.000000000000000000000000000000000000000000000000000000000000177 223.0
HKD1_k127_6867708_29 - - - - 0.0000000000000000000000000000000000000000000000000036 190.0
HKD1_k127_6867708_3 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 4.367e-203 638.0
HKD1_k127_6867708_30 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000431 174.0
HKD1_k127_6867708_31 PQQ-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000189 181.0
HKD1_k127_6867708_32 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000006639 161.0
HKD1_k127_6867708_33 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000000000000000002218 174.0
HKD1_k127_6867708_34 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000005054 160.0
HKD1_k127_6867708_35 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000000000000000000000000003893 149.0
HKD1_k127_6867708_37 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.000000000000000000000000000000005971 142.0
HKD1_k127_6867708_38 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000002254 128.0
HKD1_k127_6867708_39 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000002471 123.0
HKD1_k127_6867708_4 Aromatic amino acid lyase K01745 - 4.3.1.3 1.812e-196 623.0
HKD1_k127_6867708_40 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000006067 124.0
HKD1_k127_6867708_41 Histidine kinase - - - 0.0000000000000000000000008213 110.0
HKD1_k127_6867708_42 von Willebrand factor, type A K07114 - - 0.000000000000000000000002944 117.0
HKD1_k127_6867708_43 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000006601 109.0
HKD1_k127_6867708_44 Trm112p-like protein K09791 - - 0.00000000000000000000008205 98.0
HKD1_k127_6867708_45 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.0000000000000000000003601 107.0
HKD1_k127_6867708_47 Putative adhesin - - - 0.0000000000000000002673 99.0
HKD1_k127_6867708_48 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000302 94.0
HKD1_k127_6867708_49 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.000000000000007792 87.0
HKD1_k127_6867708_5 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 603.0
HKD1_k127_6867708_52 - - - - 0.0000000004075 70.0
HKD1_k127_6867708_53 - - - - 0.00000002535 55.0
HKD1_k127_6867708_54 - - - - 0.00000004516 64.0
HKD1_k127_6867708_55 MacB-like periplasmic core domain - - - 0.000003205 56.0
HKD1_k127_6867708_56 Cupin - - - 0.000006732 54.0
HKD1_k127_6867708_57 DinB superfamily - - - 0.00001116 54.0
HKD1_k127_6867708_58 Putative zinc-finger - - - 0.00002176 55.0
HKD1_k127_6867708_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 584.0
HKD1_k127_6867708_60 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00005265 51.0
HKD1_k127_6867708_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 535.0
HKD1_k127_6867708_8 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 503.0
HKD1_k127_6867708_9 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 505.0
HKD1_k127_6985075_0 AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 536.0
HKD1_k127_6985075_1 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 449.0
HKD1_k127_6985075_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 361.0
HKD1_k127_6985075_3 PFAM major facilitator superfamily MFS_1 K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 356.0
HKD1_k127_6985075_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000003056 244.0
HKD1_k127_6985075_5 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000000000001491 150.0
HKD1_k127_6985075_7 - - - - 0.0001491 49.0
HKD1_k127_7060801_0 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00239 - 1.3.5.1,1.3.5.4 1.247e-273 852.0
HKD1_k127_7060801_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 334.0
HKD1_k127_7060801_10 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000002646 96.0
HKD1_k127_7060801_11 PFAM PIN domain - - - 0.000000005931 61.0
HKD1_k127_7060801_12 YadA-like membrane anchor domain K12342 - - 0.00000001287 68.0
HKD1_k127_7060801_2 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000006962 191.0
HKD1_k127_7060801_3 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000000000000000006089 199.0
HKD1_k127_7060801_4 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000000003803 179.0
HKD1_k127_7060801_5 cellulose binding - - - 0.0000000000000000000000000000000000000000000002192 194.0
HKD1_k127_7060801_6 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000002065 172.0
HKD1_k127_7060801_7 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000705 127.0
HKD1_k127_7060801_8 Smr domain - - - 0.000000000000000000000000003112 113.0
HKD1_k127_7060801_9 PFAM transposase IS3 IS911 family protein - - - 0.0000000000000000001439 93.0
HKD1_k127_7071354_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein K01322,K01354 - 3.4.21.26,3.4.21.83 4.101e-259 817.0
HKD1_k127_7071354_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 366.0
HKD1_k127_7071354_2 Oxidoreductase, molybdopterin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 286.0
HKD1_k127_7071354_3 Cupin domain - - - 0.0000000000000000000000000000000000000000000006454 168.0
HKD1_k127_7071354_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000002266 74.0
HKD1_k127_7071354_5 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000001598 64.0
HKD1_k127_7081475_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000007478 212.0
HKD1_k127_7081475_1 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000009889 160.0
HKD1_k127_7081475_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000001239 143.0
HKD1_k127_7081475_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000001521 96.0
HKD1_k127_7081475_4 cheY-homologous receiver domain - - - 0.000000000000000001788 89.0
HKD1_k127_7081475_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000005316 64.0
HKD1_k127_708508_0 cellulose binding - - - 0.0 1354.0
HKD1_k127_708508_1 Protein tyrosine kinase - - - 2.319e-225 728.0
HKD1_k127_708508_10 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 511.0
HKD1_k127_708508_11 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 506.0
HKD1_k127_708508_12 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 446.0
HKD1_k127_708508_13 Peptidase family M49 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 432.0
HKD1_k127_708508_14 X-Pro dipeptidyl-peptidase (S15 family) K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 449.0
HKD1_k127_708508_15 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 377.0
HKD1_k127_708508_16 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 320.0
HKD1_k127_708508_17 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 331.0
HKD1_k127_708508_18 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 314.0
HKD1_k127_708508_19 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 308.0
HKD1_k127_708508_2 Involved in the tonB-independent uptake of proteins - - - 3.726e-204 664.0
HKD1_k127_708508_20 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 284.0
HKD1_k127_708508_21 - - - - 0.000000000000000000000000000000000000000000001922 173.0
HKD1_k127_708508_22 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000001143 152.0
HKD1_k127_708508_23 - - - - 0.00000000000000000000000118 115.0
HKD1_k127_708508_24 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000008838 103.0
HKD1_k127_708508_25 helix_turn_helix, Lux Regulon - - - 0.00000000004335 68.0
HKD1_k127_708508_26 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000002142 59.0
HKD1_k127_708508_27 Transposase K07491 - - 0.000000003315 61.0
HKD1_k127_708508_28 Protein kinase domain K12132 - 2.7.11.1 0.0000005356 55.0
HKD1_k127_708508_3 Protein kinase domain K12132 - 2.7.11.1 2.359e-198 649.0
HKD1_k127_708508_4 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 625.0
HKD1_k127_708508_5 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 584.0
HKD1_k127_708508_6 GvpD gas vesicle protein K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 554.0
HKD1_k127_708508_7 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 574.0
HKD1_k127_708508_8 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 561.0
HKD1_k127_708508_9 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 510.0
HKD1_k127_7201187_0 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 1.292e-198 623.0
HKD1_k127_7201187_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 491.0
HKD1_k127_7201187_2 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 455.0
HKD1_k127_7201187_3 Amidinotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 333.0
HKD1_k127_7201187_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000125 269.0
HKD1_k127_7201187_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000001163 236.0
HKD1_k127_7218395_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 4.893e-241 757.0
HKD1_k127_7218395_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 495.0
HKD1_k127_7218395_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001823 283.0
HKD1_k127_7218395_11 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000003744 243.0
HKD1_k127_7218395_12 Chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005749 248.0
HKD1_k127_7218395_13 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000000000000000000004368 234.0
HKD1_k127_7218395_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001787 231.0
HKD1_k127_7218395_15 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000003579 231.0
HKD1_k127_7218395_16 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000003973 231.0
HKD1_k127_7218395_17 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000692 216.0
HKD1_k127_7218395_18 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000001855 213.0
HKD1_k127_7218395_19 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000111 201.0
HKD1_k127_7218395_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 478.0
HKD1_k127_7218395_20 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000001545 185.0
HKD1_k127_7218395_21 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000004269 173.0
HKD1_k127_7218395_22 Polysaccharide deacetylase - - - 0.000000000000000000000000000001541 131.0
HKD1_k127_7218395_23 Outer membrane efflux protein - - - 0.0000000000000000000000000002836 131.0
HKD1_k127_7218395_24 -O-antigen - - - 0.0000000000000000000000006418 120.0
HKD1_k127_7218395_25 Polysaccharide biosynthesis protein - - - 0.00000000001849 76.0
HKD1_k127_7218395_26 Preprotein translocase SecG subunit K03075 - - 0.0000000125 61.0
HKD1_k127_7218395_27 protein tyrosine kinase activity - - - 0.00000003724 63.0
HKD1_k127_7218395_28 - - - - 0.000003141 53.0
HKD1_k127_7218395_3 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 451.0
HKD1_k127_7218395_4 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 437.0
HKD1_k127_7218395_5 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 411.0
HKD1_k127_7218395_6 PFAM glycoside hydrolase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000787 389.0
HKD1_k127_7218395_7 Glycosyltransferase Family 4 K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 332.0
HKD1_k127_7218395_8 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 331.0
HKD1_k127_7218395_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 307.0
HKD1_k127_7237569_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0 1034.0
HKD1_k127_7237569_1 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 5.837e-281 870.0
HKD1_k127_7237569_10 Glycosyl hydrolase family 3 K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 348.0
HKD1_k127_7237569_11 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007337 317.0
HKD1_k127_7237569_12 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 317.0
HKD1_k127_7237569_13 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 304.0
HKD1_k127_7237569_14 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 321.0
HKD1_k127_7237569_15 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000001796 249.0
HKD1_k127_7237569_16 MFS/sugar transport protein K03292 - - 0.0000003243 53.0
HKD1_k127_7237569_2 ASPIC and UnbV - - - 8.283e-218 694.0
HKD1_k127_7237569_3 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 6.23e-216 679.0
HKD1_k127_7237569_4 Cytochrome c554 and c-prime - - - 3.596e-197 638.0
HKD1_k127_7237569_5 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 598.0
HKD1_k127_7237569_6 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 576.0
HKD1_k127_7237569_7 xylose isomerase activity K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 565.0
HKD1_k127_7237569_8 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 535.0
HKD1_k127_7237569_9 Alpha galactosidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 518.0
HKD1_k127_7275947_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.486e-302 945.0
HKD1_k127_7275947_1 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 564.0
HKD1_k127_7275947_2 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 557.0
HKD1_k127_7275947_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000000002471 234.0
HKD1_k127_7275947_4 chaperone-mediated protein folding - - - 0.000000000000004534 79.0
HKD1_k127_7275947_5 lysyltransferase activity K07027 - - 0.000000000001062 79.0
HKD1_k127_7275947_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00009868 55.0
HKD1_k127_7301832_0 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 3.291e-311 966.0
HKD1_k127_7301832_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 586.0
HKD1_k127_7301832_10 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 324.0
HKD1_k127_7301832_11 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 318.0
HKD1_k127_7301832_12 MafB19-like deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000003124 232.0
HKD1_k127_7301832_13 membrane - - - 0.00000000000000000000000000000000000000000000000000000003266 203.0
HKD1_k127_7301832_15 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000004379 185.0
HKD1_k127_7301832_16 - - - - 0.0000000000000000000000000000000000000000000004192 177.0
HKD1_k127_7301832_17 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000001256 152.0
HKD1_k127_7301832_18 Hep Hag repeat protein - - - 0.0000000000000000000004978 111.0
HKD1_k127_7301832_19 - - - - 0.000000000000000000001732 100.0
HKD1_k127_7301832_2 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 542.0
HKD1_k127_7301832_20 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000004606 86.0
HKD1_k127_7301832_21 Glucose Sorbosone dehydrogenase - - - 0.000000000000002376 88.0
HKD1_k127_7301832_23 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000001832 72.0
HKD1_k127_7301832_24 Sigma-70, region 4 K03088 - - 0.0000007465 57.0
HKD1_k127_7301832_25 Collagen triple helix repeat (20 copies) - - - 0.000577 52.0
HKD1_k127_7301832_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 487.0
HKD1_k127_7301832_4 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 503.0
HKD1_k127_7301832_5 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 480.0
HKD1_k127_7301832_6 cellulose binding K13735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 432.0
HKD1_k127_7301832_7 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 385.0
HKD1_k127_7301832_8 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 340.0
HKD1_k127_7301832_9 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 351.0
HKD1_k127_7304836_0 PFAM Glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 1.48e-230 723.0
HKD1_k127_7304836_1 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 537.0
HKD1_k127_7304836_2 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 417.0
HKD1_k127_7304836_3 Peptidase of plants and bacteria - - - 0.000000000000000000000000000000000000000000000000001306 191.0
HKD1_k127_7304836_4 Domain of unknown function (DUF4440) - - - 0.00000000000504 70.0
HKD1_k127_7308195_0 MacB-like periplasmic core domain - - - 3.609e-273 862.0
HKD1_k127_7308195_1 efflux transmembrane transporter activity - - - 1.607e-247 788.0
HKD1_k127_7308195_10 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 625.0
HKD1_k127_7308195_11 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 577.0
HKD1_k127_7308195_12 A-macroglobulin complement component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 637.0
HKD1_k127_7308195_13 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 599.0
HKD1_k127_7308195_14 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 526.0
HKD1_k127_7308195_15 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 525.0
HKD1_k127_7308195_16 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 503.0
HKD1_k127_7308195_17 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 519.0
HKD1_k127_7308195_18 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 465.0
HKD1_k127_7308195_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 434.0
HKD1_k127_7308195_2 MacB-like periplasmic core domain - - - 6.209e-245 781.0
HKD1_k127_7308195_20 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 384.0
HKD1_k127_7308195_21 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 348.0
HKD1_k127_7308195_22 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 337.0
HKD1_k127_7308195_23 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 294.0
HKD1_k127_7308195_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000014 277.0
HKD1_k127_7308195_25 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000002926 236.0
HKD1_k127_7308195_26 Ndr family - - - 0.00000000000000000000000000000000000000000000000000002191 201.0
HKD1_k127_7308195_27 Peptidase family M23 K21472 - - 0.000000000000000000000000000000000000000000000004914 179.0
HKD1_k127_7308195_28 efflux transmembrane transporter activity - - - 0.0000000000000000009414 90.0
HKD1_k127_7308195_29 ErfK ybiS ycfS ynhG family protein K16291 - - 0.00000000000004928 85.0
HKD1_k127_7308195_3 MacB-like periplasmic core domain - - - 5.568e-223 717.0
HKD1_k127_7308195_30 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000004869 70.0
HKD1_k127_7308195_31 MacB-like periplasmic core domain - - - 0.000000004741 66.0
HKD1_k127_7308195_4 efflux transmembrane transporter activity - - - 1.626e-217 704.0
HKD1_k127_7308195_5 efflux transmembrane transporter activity K02004 - - 6.45e-216 696.0
HKD1_k127_7308195_6 efflux transmembrane transporter activity K02004 - - 1.205e-215 695.0
HKD1_k127_7308195_7 efflux transmembrane transporter activity K02004 - - 2.425e-208 674.0
HKD1_k127_7308195_8 efflux transmembrane transporter activity K02004 - - 2.802e-204 662.0
HKD1_k127_7308195_9 efflux transmembrane transporter activity K02004 - - 1.082e-199 649.0
HKD1_k127_731543_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 8.867e-221 697.0
HKD1_k127_731543_1 Peptidase S46 - - - 1.412e-219 702.0
HKD1_k127_731543_10 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000001124 239.0
HKD1_k127_731543_11 NAD dependent epimerase/dehydratase family K07535 - - 0.00000000000000000000000000000000000000000000000000000000000000002165 231.0
HKD1_k127_731543_12 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000142 235.0
HKD1_k127_731543_13 CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000001808 190.0
HKD1_k127_731543_14 Universal stress protein family - - - 0.000000000000000000000000000000000001385 152.0
HKD1_k127_731543_15 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000002447 144.0
HKD1_k127_731543_16 DNA polymerase K02347 - - 0.000000000000000000000000000006723 125.0
HKD1_k127_731543_17 PFAM response regulator receiver K11443 - - 0.00000000000000000000001996 106.0
HKD1_k127_731543_18 FeoA K04758 - - 0.000000000007308 68.0
HKD1_k127_731543_19 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000008607 63.0
HKD1_k127_731543_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.799e-204 642.0
HKD1_k127_731543_20 LssY C-terminus - - - 0.00002873 56.0
HKD1_k127_731543_3 Major Facilitator Superfamily - - - 6.812e-194 618.0
HKD1_k127_731543_4 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 553.0
HKD1_k127_731543_5 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 449.0
HKD1_k127_731543_6 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 394.0
HKD1_k127_731543_7 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 307.0
HKD1_k127_731543_8 benzoyl-CoA reductase K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 306.0
HKD1_k127_731543_9 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004001 275.0
HKD1_k127_734871_0 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 596.0
HKD1_k127_734871_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 542.0
HKD1_k127_734871_10 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002459 288.0
HKD1_k127_734871_11 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000008513 225.0
HKD1_k127_734871_12 CHAT domain K03641 - - 0.00000000000000000000000000000000000000000000000000000000000001169 243.0
HKD1_k127_734871_13 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000001102 214.0
HKD1_k127_734871_14 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000002547 198.0
HKD1_k127_734871_15 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000006025 194.0
HKD1_k127_734871_16 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000001817 159.0
HKD1_k127_734871_17 Cupin domain - - - 0.0000000000000000000000000000000000005935 145.0
HKD1_k127_734871_18 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000001071 136.0
HKD1_k127_734871_19 Protein of unknown function (DUF1326) - - - 0.000000000000000000004119 104.0
HKD1_k127_734871_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 466.0
HKD1_k127_734871_20 Mo-molybdopterin cofactor metabolic process K03636,K21147 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.80,2.8.1.11 0.00000000000131 71.0
HKD1_k127_734871_21 - - - - 0.000001273 60.0
HKD1_k127_734871_3 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 481.0
HKD1_k127_734871_4 RmlD substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 428.0
HKD1_k127_734871_5 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 415.0
HKD1_k127_734871_6 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 370.0
HKD1_k127_734871_7 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 356.0
HKD1_k127_734871_8 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 317.0
HKD1_k127_734871_9 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 318.0
HKD1_k127_7506514_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 469.0
HKD1_k127_7506514_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 345.0
HKD1_k127_7506514_2 Phosphoribosyl transferase domain K00760,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000001114 217.0
HKD1_k127_7506514_3 Encoded by - - - 0.00000000000000000000000000000000000000000000000000000002709 221.0
HKD1_k127_7548859_0 PA14 domain K05349 - 3.2.1.21 0.0 1355.0
HKD1_k127_7548859_1 Carboxypeptidase regulatory-like domain - - - 0.0 1303.0
HKD1_k127_7548859_10 Putative esterase K07214 - - 7.779e-202 634.0
HKD1_k127_7548859_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 625.0
HKD1_k127_7548859_12 Aldehyde dehydrogenase family K13877 - 1.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 589.0
HKD1_k127_7548859_13 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 407.0
HKD1_k127_7548859_14 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 383.0
HKD1_k127_7548859_15 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 363.0
HKD1_k127_7548859_16 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 360.0
HKD1_k127_7548859_17 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 335.0
HKD1_k127_7548859_18 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 350.0
HKD1_k127_7548859_19 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 341.0
HKD1_k127_7548859_2 Sulfate permease family - - - 5.004e-298 923.0
HKD1_k127_7548859_20 cephalosporin-C deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 337.0
HKD1_k127_7548859_21 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 321.0
HKD1_k127_7548859_22 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 291.0
HKD1_k127_7548859_23 pathogenesis K01460 - 3.5.1.78,6.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000001929 245.0
HKD1_k127_7548859_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000001406 218.0
HKD1_k127_7548859_25 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000002932 148.0
HKD1_k127_7548859_26 Carboxypeptidase regulatory-like domain - - - 0.000000000000000001491 88.0
HKD1_k127_7548859_27 DinB superfamily - - - 0.00000000000000001078 89.0
HKD1_k127_7548859_28 Transposase IS200 like - - - 0.00000008619 54.0
HKD1_k127_7548859_29 bacterial OsmY and nodulation domain - - - 0.000009836 55.0
HKD1_k127_7548859_3 Belongs to the glycosyl hydrolase 43 family K01198 - 3.2.1.37 3.344e-293 907.0
HKD1_k127_7548859_30 PFAM helix-turn-helix, Fis-type - - - 0.00007865 48.0
HKD1_k127_7548859_32 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0001525 47.0
HKD1_k127_7548859_33 COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain K03974 - - 0.000182 49.0
HKD1_k127_7548859_4 Belongs to the IlvD Edd family K22396 - 4.2.1.82 8.375e-273 854.0
HKD1_k127_7548859_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.003e-267 832.0
HKD1_k127_7548859_6 Belongs to the glycosyl hydrolase 43 family K06113 - 3.2.1.99 1.372e-243 760.0
HKD1_k127_7548859_7 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 2.018e-242 775.0
HKD1_k127_7548859_8 PFAM Major Facilitator Superfamily K08191 - - 6.808e-212 664.0
HKD1_k127_7548859_9 cell adhesion involved in biofilm formation K02014,K11031 - - 5.112e-202 675.0
HKD1_k127_7620391_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.132e-282 883.0
HKD1_k127_7620391_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 407.0
HKD1_k127_7620391_10 YbbR-like protein - - - 0.00004984 51.0
HKD1_k127_7620391_11 Carboxypeptidase regulatory-like domain - - - 0.00005674 51.0
HKD1_k127_7620391_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008202 293.0
HKD1_k127_7620391_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000002748 225.0
HKD1_k127_7620391_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001296 221.0
HKD1_k127_7620391_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000002464 210.0
HKD1_k127_7620391_6 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000001679 203.0
HKD1_k127_7620391_7 domain protein - - - 0.0000000000000000000000005659 121.0
HKD1_k127_7620391_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000001202 85.0
HKD1_k127_7620391_9 peptidyl-tyrosine sulfation - - - 0.0000000005229 69.0
HKD1_k127_7722206_0 Pyruvate kinase K00873 - 2.7.1.40 3.298e-200 644.0
HKD1_k127_7722206_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 574.0
HKD1_k127_7722206_10 esterase lipase - - - 0.0000000000000000000000001372 110.0
HKD1_k127_7722206_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000005266 93.0
HKD1_k127_7722206_2 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001308 269.0
HKD1_k127_7722206_3 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000000000000000000000000000366 191.0
HKD1_k127_7722206_4 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000606 192.0
HKD1_k127_7722206_5 Protein of unknown function (DUF1203) - - - 0.00000000000000000000000000000000000000000000008941 175.0
HKD1_k127_7722206_6 Cytochrome P460 - - - 0.000000000000000000000000000000000000000003847 160.0
HKD1_k127_7722206_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000003575 135.0
HKD1_k127_7722206_8 - - - - 0.000000000000000000000000000000005929 133.0
HKD1_k127_7722206_9 Protein of unknown function (DUF3788) - - - 0.00000000000000000000000000001938 123.0
HKD1_k127_774313_0 Sortilin, neurotensin receptor 3, - - - 0.0 1386.0
HKD1_k127_774313_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 6.162e-203 646.0
HKD1_k127_774313_10 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 415.0
HKD1_k127_774313_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 417.0
HKD1_k127_774313_12 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 403.0
HKD1_k127_774313_13 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 396.0
HKD1_k127_774313_14 Transcriptional regulator K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 364.0
HKD1_k127_774313_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 340.0
HKD1_k127_774313_16 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 323.0
HKD1_k127_774313_17 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 323.0
HKD1_k127_774313_18 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 331.0
HKD1_k127_774313_19 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 317.0
HKD1_k127_774313_2 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 595.0
HKD1_k127_774313_20 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001183 286.0
HKD1_k127_774313_21 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001285 285.0
HKD1_k127_774313_23 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001949 262.0
HKD1_k127_774313_24 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000159 247.0
HKD1_k127_774313_25 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001468 247.0
HKD1_k127_774313_26 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000005229 239.0
HKD1_k127_774313_27 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000001189 212.0
HKD1_k127_774313_28 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000227 215.0
HKD1_k127_774313_29 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000005909 205.0
HKD1_k127_774313_3 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 565.0
HKD1_k127_774313_30 - - - - 0.000000000000000000000000000000000000000000000000002067 193.0
HKD1_k127_774313_31 FR47-like protein K03829 - - 0.00000000000000000000000000000000000000000000000004974 182.0
HKD1_k127_774313_32 - - - - 0.00000000000000000000000000000000000000000000000456 177.0
HKD1_k127_774313_33 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000006683 187.0
HKD1_k127_774313_34 Transcription factor zinc-finger - - - 0.000000000000000000000000000000000000000000000769 172.0
HKD1_k127_774313_35 Histidine kinase K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000002231 178.0
HKD1_k127_774313_36 Multicopper oxidase K04753 - - 0.000000000000000000000000000000000000000007063 175.0
HKD1_k127_774313_37 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000008184 159.0
HKD1_k127_774313_38 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000001099 162.0
HKD1_k127_774313_39 - - - - 0.00000000000000000000000000000000000001006 156.0
HKD1_k127_774313_4 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 551.0
HKD1_k127_774313_40 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000001245 151.0
HKD1_k127_774313_41 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.00000000000000000000000000000001041 130.0
HKD1_k127_774313_42 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000001305 145.0
HKD1_k127_774313_43 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000001395 118.0
HKD1_k127_774313_44 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000000000000000000000000004383 117.0
HKD1_k127_774313_45 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000000000000000002035 115.0
HKD1_k127_774313_46 Phage integrase, N-terminal SAM-like domain K14059 - - 0.000000000000000000000000004594 125.0
HKD1_k127_774313_47 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000005344 116.0
HKD1_k127_774313_48 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000008829 110.0
HKD1_k127_774313_49 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K21025 - - 0.00000000000000000000001568 113.0
HKD1_k127_774313_5 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 506.0
HKD1_k127_774313_50 Transcriptional regulator - - - 0.0000000000000000000456 93.0
HKD1_k127_774313_51 Pfam:N_methyl_2 - - - 0.000000000000000000193 94.0
HKD1_k127_774313_52 Pfam:N_methyl_2 - - - 0.0000000000000000002729 95.0
HKD1_k127_774313_53 Pfam:N_methyl_2 - - - 0.000000000000000006679 89.0
HKD1_k127_774313_54 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000008292 85.0
HKD1_k127_774313_55 metallopeptidase activity K01387 - 3.4.24.3 0.0000000000000002246 96.0
HKD1_k127_774313_56 Psort location CytoplasmicMembrane, score - - - 0.000000000000003683 89.0
HKD1_k127_774313_57 - - - - 0.000000000000006771 77.0
HKD1_k127_774313_58 peptidyl-tyrosine sulfation - - - 0.000000000000006852 88.0
HKD1_k127_774313_59 Methyltransferase domain - - - 0.000000000000008656 84.0
HKD1_k127_774313_6 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 495.0
HKD1_k127_774313_60 Pfam:N_methyl_2 - - - 0.000000000000072 78.0
HKD1_k127_774313_61 - - - - 0.000000000002483 76.0
HKD1_k127_774313_62 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000005218 78.0
HKD1_k127_774313_64 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000005492 60.0
HKD1_k127_774313_66 methylase - - - 0.000004529 52.0
HKD1_k127_774313_67 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000007715 59.0
HKD1_k127_774313_68 cation transport ATPase K01533,K17686 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.4,3.6.3.54 0.0001288 50.0
HKD1_k127_774313_7 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 475.0
HKD1_k127_774313_8 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 519.0
HKD1_k127_774313_9 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 518.0
HKD1_k127_7807798_0 Belongs to the ClpA ClpB family K03696 - - 5.985e-257 814.0
HKD1_k127_7807798_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 571.0
HKD1_k127_7807798_10 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.0000000000000000000000000000000000000001616 163.0
HKD1_k127_7807798_11 iron ion binding - - - 0.00000000000000000000000001444 120.0
HKD1_k127_7807798_12 Domain of unknown function (DUF4081) K06976 - - 0.000000000000000000009835 103.0
HKD1_k127_7807798_13 nuclear chromosome segregation - - - 0.0000000000000000001579 102.0
HKD1_k127_7807798_14 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04757 - 2.7.11.1 0.0000000000000000005222 97.0
HKD1_k127_7807798_15 Reprolysin (M12B) family zinc metalloprotease - - - 0.00000000000000002357 97.0
HKD1_k127_7807798_16 - - - - 0.00000000000116 78.0
HKD1_k127_7807798_17 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000001178 73.0
HKD1_k127_7807798_2 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 554.0
HKD1_k127_7807798_3 cellulose binding K13735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 422.0
HKD1_k127_7807798_4 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 353.0
HKD1_k127_7807798_5 Peptidase family M49 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 302.0
HKD1_k127_7807798_6 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000001006 248.0
HKD1_k127_7807798_7 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000002452 221.0
HKD1_k127_7807798_8 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000007078 163.0
HKD1_k127_7807798_9 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000002842 164.0
HKD1_k127_7833266_0 iron dependent repressor - - - 0.00000000000000000000000000000000000000000000001323 191.0
HKD1_k127_7833266_1 COG3209 Rhs family protein - - - 0.0000000000000001041 86.0
HKD1_k127_7833266_2 rhs family - - - 0.0000000002743 66.0
HKD1_k127_7847424_0 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 454.0
HKD1_k127_7847424_1 positive regulation of growth rate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 399.0
HKD1_k127_7847424_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 401.0
HKD1_k127_7847424_3 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 383.0
HKD1_k127_7847424_4 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000004881 216.0
HKD1_k127_7847424_6 23S rRNA-intervening sequence protein - - - 0.00000000000002155 74.0
HKD1_k127_7847424_7 PD-(D/E)XK nuclease superfamily - - - 0.00000000013 63.0
HKD1_k127_7927916_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1233.0
HKD1_k127_7927916_1 Carbon starvation protein K06200 - - 2.322e-212 677.0
HKD1_k127_7927916_10 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000419 131.0
HKD1_k127_7927916_11 Universal stress protein family - - - 0.00000000000000008065 90.0
HKD1_k127_7927916_12 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000009003 78.0
HKD1_k127_7927916_13 Transposase IS200 like K07491 - - 0.0006317 43.0
HKD1_k127_7927916_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 553.0
HKD1_k127_7927916_3 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 448.0
HKD1_k127_7927916_4 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 368.0
HKD1_k127_7927916_5 PFAM glycoside hydrolase family 19 K03791 - - 0.000000000000000000000000000000000000000000000000000000000000007221 226.0
HKD1_k127_7927916_6 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000004707 184.0
HKD1_k127_7927916_7 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000001893 182.0
HKD1_k127_7927916_8 BioY family K03523 - - 0.00000000000000000000000000000000000000000002008 168.0
HKD1_k127_7927916_9 - - - - 0.0000000000000000000000000000001545 130.0
HKD1_k127_7948185_0 cellulose binding - - - 0.0 1086.0
HKD1_k127_7948185_1 cellulose binding - - - 2.059e-280 894.0
HKD1_k127_7948185_10 Forkhead associated domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 368.0
HKD1_k127_7948185_11 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 340.0
HKD1_k127_7948185_12 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 339.0
HKD1_k127_7948185_13 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002081 278.0
HKD1_k127_7948185_14 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000002257 227.0
HKD1_k127_7948185_15 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000002594 225.0
HKD1_k127_7948185_16 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000001794 211.0
HKD1_k127_7948185_17 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000001343 210.0
HKD1_k127_7948185_18 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000004163 179.0
HKD1_k127_7948185_19 Low affinity iron permease - - - 0.000000000000000000000000000000000000000004098 158.0
HKD1_k127_7948185_2 Dienelactone hydrolase family - - - 6.51e-265 832.0
HKD1_k127_7948185_20 - - - - 0.0000000000000000000000000000000004901 145.0
HKD1_k127_7948185_21 oxidoreductase activity - - - 0.00000000000000000000000000000003957 145.0
HKD1_k127_7948185_22 von Willebrand factor, type A - - - 0.0000000000000000000000000005539 126.0
HKD1_k127_7948185_23 Zn peptidase K21686 - - 0.000000000000000000000000007163 117.0
HKD1_k127_7948185_24 - - - - 0.00000000000000000000000008463 111.0
HKD1_k127_7948185_25 - - - - 0.0000000000000000000000007026 109.0
HKD1_k127_7948185_26 PFAM Transposase K07491 - - 0.0000000000000000000008137 101.0
HKD1_k127_7948185_27 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.000000000000000000003068 99.0
HKD1_k127_7948185_28 PFAM regulatory protein GntR HTH K07979 - - 0.00000000000000000005351 94.0
HKD1_k127_7948185_29 iron ion homeostasis - - - 0.00000000000000003765 93.0
HKD1_k127_7948185_3 Hydrolase CocE NonD family K06978 - - 1.531e-248 788.0
HKD1_k127_7948185_30 Domain of unknown function (DU1801) - - - 0.00000000000002521 79.0
HKD1_k127_7948185_31 Integrase core domain - - - 0.0000000004035 64.0
HKD1_k127_7948185_32 Peptidase P60 K21471 - - 0.0000000007955 69.0
HKD1_k127_7948185_33 Cysteine-rich CWC - - - 0.0000001494 56.0
HKD1_k127_7948185_34 - - - - 0.0000144 53.0
HKD1_k127_7948185_35 oxidoreductase activity - - - 0.00002112 57.0
HKD1_k127_7948185_36 sequence-specific DNA binding - - - 0.0003772 48.0
HKD1_k127_7948185_37 - - - - 0.0007647 44.0
HKD1_k127_7948185_4 DNA polymerase beta thumb K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 620.0
HKD1_k127_7948185_5 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 500.0
HKD1_k127_7948185_6 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 468.0
HKD1_k127_7948185_7 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 375.0
HKD1_k127_7948185_8 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 377.0
HKD1_k127_7948185_9 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 374.0
HKD1_k127_8001695_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 385.0
HKD1_k127_8001695_1 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002305 289.0
HKD1_k127_867201_0 Carboxypeptidase regulatory-like domain - - - 7.363e-312 996.0
HKD1_k127_867201_1 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 550.0
HKD1_k127_867201_10 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000005184 198.0
HKD1_k127_867201_11 PhoU domain K02039 - - 0.00000000000000000000000000000000000000000000005829 177.0
HKD1_k127_867201_12 phosphorelay signal transduction system K19622 - - 0.00000000000000000001636 97.0
HKD1_k127_867201_13 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.000000000000000004009 84.0
HKD1_k127_867201_14 cheY-homologous receiver domain - - - 0.00000000005918 76.0
HKD1_k127_867201_15 Putative porin - - - 0.0000001519 64.0
HKD1_k127_867201_2 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 479.0
HKD1_k127_867201_3 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 428.0
HKD1_k127_867201_4 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 406.0
HKD1_k127_867201_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 334.0
HKD1_k127_867201_6 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 334.0
HKD1_k127_867201_7 PAS domain containing protein K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 340.0
HKD1_k127_867201_8 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 289.0
HKD1_k127_867201_9 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000395 256.0
HKD1_k127_905437_0 Belongs to the glycosyl hydrolase 43 family - - - 1.763e-233 733.0
HKD1_k127_905437_1 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 1.365e-213 673.0
HKD1_k127_905437_2 PFAM Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 507.0
HKD1_k127_905437_3 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 385.0
HKD1_k127_905437_4 Domain of unknown function (DUF4861) K01051 - 3.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000005908 239.0
HKD1_k127_905437_5 Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and or methyl galactoside import. Responsible for energy coupling to the transport system K17215 - - 0.00000000000000000000004688 100.0
HKD1_k127_917780_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 439.0
HKD1_k127_917780_10 - - - - 0.0000000001183 71.0
HKD1_k127_917780_11 Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 0.00002731 51.0
HKD1_k127_917780_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 414.0
HKD1_k127_917780_3 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 388.0
HKD1_k127_917780_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000001111 252.0
HKD1_k127_917780_5 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000001516 215.0
HKD1_k127_917780_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000001571 220.0
HKD1_k127_917780_7 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000005795 113.0
HKD1_k127_917780_8 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.00000000000008479 76.0
HKD1_k127_917780_9 multi-organism process - - - 0.000000000008891 76.0
HKD1_k127_944224_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0 1056.0
HKD1_k127_944224_1 cellulose binding - - - 5.834e-307 978.0
HKD1_k127_944224_10 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000002057 105.0
HKD1_k127_944224_11 RDD family - - - 0.000000004128 68.0
HKD1_k127_944224_2 serine threonine protein kinase K12132 - 2.7.11.1 5.414e-214 698.0
HKD1_k127_944224_3 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 584.0
HKD1_k127_944224_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000002308 224.0
HKD1_k127_944224_5 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000005085 218.0
HKD1_k127_944224_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000008543 175.0
HKD1_k127_944224_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000001528 175.0
HKD1_k127_944224_8 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000001952 165.0
HKD1_k127_944224_9 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000006644 118.0
HKD1_k127_963805_0 alpha-L-rhamnosidase - - - 0.0 1433.0
HKD1_k127_963805_1 alpha beta - - - 3.075e-209 657.0
HKD1_k127_963805_10 metallopeptidase activity - - - 0.000000000000000000000000000000000183 143.0
HKD1_k127_963805_11 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000007595 138.0
HKD1_k127_963805_12 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000007313 73.0
HKD1_k127_963805_13 GDSL-like Lipase/Acylhydrolase family - - - 0.0000002513 63.0
HKD1_k127_963805_2 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 458.0
HKD1_k127_963805_3 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 421.0
HKD1_k127_963805_4 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 320.0
HKD1_k127_963805_5 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002061 271.0
HKD1_k127_963805_6 ABC-2 type transporter K01992,K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001399 258.0
HKD1_k127_963805_7 MoaC family K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000007174 184.0
HKD1_k127_963805_8 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000005341 190.0
HKD1_k127_963805_9 O-acyltransferase activity K13018 - 2.3.1.201 0.00000000000000000000000000000000000000000846 162.0