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Overview

ID MAG01763
Name HKD1_bin.82
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Bacillota
Class Clostridia
Order Peptostreptococcales
Family Peptostreptococcaceae
Genus Romboutsia_D
Species
Assembly information
Completeness (%) 93.42
Contamination (%) 5.55
GC content (%) 28.0
N50 (bp) 57,563
Genome size (bp) 3,085,929

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2893

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1009787_0 His Kinase A (phosphoacceptor) domain - - - 1.242e-236 741.0
HKD1_k127_1009787_1 nucleotide catabolic process K01119 - 3.1.3.6,3.1.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 609.0
HKD1_k127_1009787_10 - - - - 0.000000000000000000000000000009929 119.0
HKD1_k127_1009787_13 Protein of unknown function (DUF1659) - - - 0.00000000000000000002775 93.0
HKD1_k127_1009787_14 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000004198 89.0
HKD1_k127_1009787_15 Protein of unknown function (DUF2922) - - - 0.000000000000009395 75.0
HKD1_k127_1009787_18 - - - - 0.00000003969 56.0
HKD1_k127_1009787_19 - - - - 0.000001007 54.0
HKD1_k127_1009787_2 Initiator Replication protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 583.0
HKD1_k127_1009787_21 Initiator Replication protein - - - 0.0009726 42.0
HKD1_k127_1009787_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 437.0
HKD1_k127_1009787_4 YoaP-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 406.0
HKD1_k127_1009787_6 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000003046 180.0
HKD1_k127_1009787_7 - - - - 0.000000000000000000000000000000004051 138.0
HKD1_k127_1009787_8 Protein of unknown function (DUF2922) - - - 0.000000000000000000000000000000009082 127.0
HKD1_k127_1009787_9 Initiator Replication protein - - - 0.0000000000000000000000000000001264 125.0
HKD1_k127_1141683_0 phosphoribosylformylglycinamidine synthase K01952 - 6.3.5.3 0.0 1592.0
HKD1_k127_1141683_1 Cadmium-exporting ATPase K01534 - 3.6.3.3,3.6.3.5 0.0 1308.0
HKD1_k127_1141683_10 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.673e-294 906.0
HKD1_k127_1141683_11 Cation transport protein K03498 - - 1.35e-279 864.0
HKD1_k127_1141683_12 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00260,K00261 - 1.4.1.2,1.4.1.3 3.986e-277 853.0
HKD1_k127_1141683_13 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 5.809e-275 848.0
HKD1_k127_1141683_14 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.275e-271 837.0
HKD1_k127_1141683_15 MatE - - - 1.105e-249 775.0
HKD1_k127_1141683_16 Amidohydrolase family - - - 1.636e-239 741.0
HKD1_k127_1141683_17 Belongs to the GARS family K01945 - 6.3.4.13 5.121e-236 734.0
HKD1_k127_1141683_18 permease K06901 - - 5.865e-225 703.0
HKD1_k127_1141683_19 Permease family K06901 - - 9.019e-223 697.0
HKD1_k127_1141683_2 Tex-like protein K06959 - - 0.0 1284.0
HKD1_k127_1141683_20 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 4.636e-208 649.0
HKD1_k127_1141683_21 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 3.602e-201 628.0
HKD1_k127_1141683_22 - - - - 2.438e-200 627.0
HKD1_k127_1141683_23 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 5.905e-194 608.0
HKD1_k127_1141683_24 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 611.0
HKD1_k127_1141683_25 Spore photoproduct lyase K03716 GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0016829,GO:0016830,GO:0043167,GO:0043169,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0070283,GO:0140097 4.1.99.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 593.0
HKD1_k127_1141683_26 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 592.0
HKD1_k127_1141683_27 Cys/Met metabolism PLP-dependent enzyme K00639,K00652,K01906 - 2.3.1.29,2.3.1.47,6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 592.0
HKD1_k127_1141683_28 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 584.0
HKD1_k127_1141683_29 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 574.0
HKD1_k127_1141683_3 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0 1193.0
HKD1_k127_1141683_30 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 561.0
HKD1_k127_1141683_31 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 561.0
HKD1_k127_1141683_32 Src homology 3 domains K20742 - 3.4.14.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 558.0
HKD1_k127_1141683_33 ATPase histidine kinase DNA gyrase B HSP90 domain protein K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 563.0
HKD1_k127_1141683_34 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 527.0
HKD1_k127_1141683_35 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 523.0
HKD1_k127_1141683_36 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 522.0
HKD1_k127_1141683_37 HAD hydrolase, family IB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 477.0
HKD1_k127_1141683_38 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 480.0
HKD1_k127_1141683_39 LysR substrate binding domain K21900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 464.0
HKD1_k127_1141683_4 ABC transporter, ATP-binding protein K06158 - - 0.0 1140.0
HKD1_k127_1141683_40 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 468.0
HKD1_k127_1141683_41 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009958 454.0
HKD1_k127_1141683_42 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 443.0
HKD1_k127_1141683_43 Universal bacterial protein YeaZ K14742 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 441.0
HKD1_k127_1141683_44 Deoxynucleoside kinase K15519 - 2.7.1.74,2.7.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 426.0
HKD1_k127_1141683_45 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 413.0
HKD1_k127_1141683_46 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 410.0
HKD1_k127_1141683_47 TipAS antibiotic-recognition domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 412.0
HKD1_k127_1141683_48 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 411.0
HKD1_k127_1141683_49 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 407.0
HKD1_k127_1141683_5 Hsp90 protein K04079 - - 0.0 1111.0
HKD1_k127_1141683_50 TrkA-N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 398.0
HKD1_k127_1141683_51 Channel protein, hemolysin III family K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 395.0
HKD1_k127_1141683_52 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 393.0
HKD1_k127_1141683_53 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 390.0
HKD1_k127_1141683_54 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 391.0
HKD1_k127_1141683_55 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 384.0
HKD1_k127_1141683_56 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 380.0
HKD1_k127_1141683_57 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 362.0
HKD1_k127_1141683_58 transcriptional regulatory protein K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 351.0
HKD1_k127_1141683_59 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 347.0
HKD1_k127_1141683_6 FtsX-like permease family K02004 - - 0.0 1032.0
HKD1_k127_1141683_60 Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 333.0
HKD1_k127_1141683_61 TraX protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 334.0
HKD1_k127_1141683_62 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 330.0
HKD1_k127_1141683_63 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 325.0
HKD1_k127_1141683_64 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 313.0
HKD1_k127_1141683_65 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 283.0
HKD1_k127_1141683_66 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003493 278.0
HKD1_k127_1141683_67 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003411 269.0
HKD1_k127_1141683_68 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000003779 240.0
HKD1_k127_1141683_69 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000001275 239.0
HKD1_k127_1141683_7 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1e-323 991.0
HKD1_k127_1141683_70 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000002509 238.0
HKD1_k127_1141683_71 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000002276 237.0
HKD1_k127_1141683_72 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.000000000000000000000000000000000000000000000000000000000000000007527 226.0
HKD1_k127_1141683_73 Protein of unknown function (DUF2975) - - - 0.0000000000000000000000000000000000000000000000000000000000006552 214.0
HKD1_k127_1141683_74 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000000004757 211.0
HKD1_k127_1141683_75 molecular chaperone DnaJ - - - 0.0000000000000000000000000000000000000000000000000000000105 200.0
HKD1_k127_1141683_76 - - - - 0.000000000000000000000000000000000000000000000000000003568 196.0
HKD1_k127_1141683_77 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000005062 190.0
HKD1_k127_1141683_78 Phosphoesterase K07095 - - 0.00000000000000000000000000000000000000000000000001525 184.0
HKD1_k127_1141683_79 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000000001351 177.0
HKD1_k127_1141683_8 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.737e-321 987.0
HKD1_k127_1141683_80 Ribosomal L25p family K02897 - - 0.00000000000000000000000000000000000000001852 153.0
HKD1_k127_1141683_81 - - - - 0.0000000000000000000000000000000000003895 141.0
HKD1_k127_1141683_82 cell division K05803 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0030674,GO:0044464,GO:0051301,GO:0060090,GO:0071944 - 0.00000000000000000000000000000000000836 139.0
HKD1_k127_1141683_83 Transcriptional regulator K07727 - - 0.0000000000000000000000000000000002868 132.0
HKD1_k127_1141683_84 Domain of unknown function (DUF4342) - - - 0.00000000000000000000000000000005233 130.0
HKD1_k127_1141683_85 - - - - 0.00000000000000000000000000000007581 130.0
HKD1_k127_1141683_86 4Fe-4S binding domain - - - 0.00000000000000000000000000002084 117.0
HKD1_k127_1141683_87 - - - - 0.0000000000000000000000001251 109.0
HKD1_k127_1141683_88 Protein of unknown function (DUF3955) - - - 0.000000000000000000003737 94.0
HKD1_k127_1141683_89 TIGRFAM RHS repeat-associated core - - - 0.00000000000000006323 81.0
HKD1_k127_1141683_9 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.583e-309 949.0
HKD1_k127_1141683_90 Transposase, Mutator family K07493 - - 0.000000000005994 69.0
HKD1_k127_1141683_92 potassium uptake protein TrkH K03498 - - 0.000005307 51.0
HKD1_k127_1141683_93 Integrase core domain - - - 0.00001483 47.0
HKD1_k127_1155760_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1098.0
HKD1_k127_1155760_1 Rhodanese Homology Domain K21028 - 2.8.1.11 1.323e-268 831.0
HKD1_k127_1155760_10 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000007252 200.0
HKD1_k127_1155760_11 - - - - 0.00000000000000000000000000000000000000000000002013 174.0
HKD1_k127_1155760_12 Protein of unknown function (DUF975) - - - 0.000000000000000000000000000000000000000000001103 172.0
HKD1_k127_1155760_13 Bacterial PH domain K09167 - - 0.000000000000000000000000000000000002225 144.0
HKD1_k127_1155760_14 Leucine Rich repeat K13730 - - 0.0000000000000000000000000000000000107 158.0
HKD1_k127_1155760_15 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02821 - 2.7.1.194 0.000000000000000000000000000000001974 134.0
HKD1_k127_1155760_16 domain protein - - - 0.000000000000000000000000000000008097 149.0
HKD1_k127_1155760_17 IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000005415 128.0
HKD1_k127_1155760_18 PTS lactose transporter subunit IIB K02822 - 2.7.1.194 0.0000000000000000000001115 100.0
HKD1_k127_1155760_19 Transposase - - - 0.0000000000000000004187 88.0
HKD1_k127_1155760_2 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 2.085e-206 646.0
HKD1_k127_1155760_3 Isocitrate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 590.0
HKD1_k127_1155760_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 466.0
HKD1_k127_1155760_5 PTS system K03475 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 460.0
HKD1_k127_1155760_6 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 447.0
HKD1_k127_1155760_7 response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001213 271.0
HKD1_k127_1155760_8 Leucine-rich repeat (LRR) protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000208 301.0
HKD1_k127_1155760_9 membrane K08981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007564 257.0
HKD1_k127_1158053_0 Pyridoxal-phosphate dependent enzyme K01751 - 4.3.1.15 6.329e-214 669.0
HKD1_k127_1158053_1 ABC transporter K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 575.0
HKD1_k127_1158053_10 transcriptional regulator domain protein - - - 0.0000001027 58.0
HKD1_k127_1158053_2 Fusaric acid resistance protein-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 524.0
HKD1_k127_1158053_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 486.0
HKD1_k127_1158053_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 315.0
HKD1_k127_1158053_5 PHP domain K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000152 280.0
HKD1_k127_1158053_6 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000761 282.0
HKD1_k127_1158053_7 Belongs to the binding-protein-dependent transport system permease family K05832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006603 248.0
HKD1_k127_1158053_8 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006053 246.0
HKD1_k127_1158053_9 MarR family - - - 0.00000000000000000000000000000000000000000000000000000000000000001508 227.0
HKD1_k127_1177316_0 Amino acid permease K03293,K11733 - - 2.527e-266 829.0
HKD1_k127_1177316_1 Isopropylmalate homocitrate citramalate K01666 - 4.1.3.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 558.0
HKD1_k127_1177316_10 - - - - 0.000000000005332 73.0
HKD1_k127_1177316_11 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000001037 68.0
HKD1_k127_1177316_12 O-Antigen ligase K18814 - - 0.00005705 55.0
HKD1_k127_1177316_2 Cytidylyltransferase K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 396.0
HKD1_k127_1177316_3 GPR1/FUN34/yaaH family K07034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 376.0
HKD1_k127_1177316_4 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 332.0
HKD1_k127_1177316_5 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004066 254.0
HKD1_k127_1177316_6 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000001153 244.0
HKD1_k127_1177316_7 YmaF family - - - 0.0000000000000000000000000000000000000000000000005387 179.0
HKD1_k127_1177316_8 VanZ like family - - - 0.0000000000000000000000000000000000000000002839 162.0
HKD1_k127_1177316_9 UDP-N-acetylglucosamine 2-epimerase activity - - - 0.0000000000000000000000000000000000000004566 163.0
HKD1_k127_1325190_0 Tetratricopeptide repeat K07126 - - 0.0 1031.0
HKD1_k127_1325190_1 Nitronate monooxygenase - - - 1.667e-208 651.0
HKD1_k127_1325190_2 aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008185 606.0
HKD1_k127_1325190_3 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 570.0
HKD1_k127_1325190_4 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 415.0
HKD1_k127_134157_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1606.0
HKD1_k127_134157_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0 1382.0
HKD1_k127_134157_10 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 540.0
HKD1_k127_134157_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 508.0
HKD1_k127_134157_12 Nitrite and sulphite reductase 4Fe-4S domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 493.0
HKD1_k127_134157_13 YbbR-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 488.0
HKD1_k127_134157_14 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 480.0
HKD1_k127_134157_15 bacterial-type flagellum organization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 427.0
HKD1_k127_134157_16 TATA-box binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 410.0
HKD1_k127_134157_17 ComF family K02242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 380.0
HKD1_k127_134157_18 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 351.0
HKD1_k127_134157_19 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 330.0
HKD1_k127_134157_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0 1168.0
HKD1_k127_134157_20 Protein of unknown function (DUF1256) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 312.0
HKD1_k127_134157_21 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 301.0
HKD1_k127_134157_22 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009691 267.0
HKD1_k127_134157_23 Stage III sporulation protein D K06283 - - 0.0000000000000000000000000000000000000000000000009219 174.0
HKD1_k127_134157_24 binding domain protein K00176 - 1.2.7.3 0.00000000000000000000000000000000000004127 143.0
HKD1_k127_134157_25 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000003202 88.0
HKD1_k127_134157_26 - - - - 0.000000000001583 68.0
HKD1_k127_134157_27 - - - - 0.00000007259 53.0
HKD1_k127_134157_28 - - - - 0.0000002088 55.0
HKD1_k127_134157_29 - - - - 0.0000009454 51.0
HKD1_k127_134157_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 8.845e-272 839.0
HKD1_k127_134157_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.202e-252 781.0
HKD1_k127_134157_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.359e-241 749.0
HKD1_k127_134157_6 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 2.128e-224 696.0
HKD1_k127_134157_7 Belongs to the acetokinase family K00929 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761 2.7.2.7 1.87e-218 679.0
HKD1_k127_134157_8 Cell shape determining protein, MreB Mrl family K03569 - - 7.076e-197 618.0
HKD1_k127_134157_9 phosphate butyryltransferase K00634 - 2.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 561.0
HKD1_k127_1392218_0 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02342,K03763 - 2.7.7.7 0.0 2636.0
HKD1_k127_1392218_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1639.0
HKD1_k127_1392218_10 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0 1045.0
HKD1_k127_1392218_100 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006621 394.0
HKD1_k127_1392218_101 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 388.0
HKD1_k127_1392218_102 Sucrose-6F-phosphate phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 385.0
HKD1_k127_1392218_103 TerD domain K05795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 380.0
HKD1_k127_1392218_104 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 383.0
HKD1_k127_1392218_105 LrgB-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 379.0
HKD1_k127_1392218_106 PucR C-terminal helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 379.0
HKD1_k127_1392218_107 TerD domain K05795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 375.0
HKD1_k127_1392218_108 Allophanate hydrolase subunit 1 K06351 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 376.0
HKD1_k127_1392218_109 TerD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 372.0
HKD1_k127_1392218_11 FtsX-like permease family - - - 0.0 1043.0
HKD1_k127_1392218_110 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 370.0
HKD1_k127_1392218_111 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 366.0
HKD1_k127_1392218_112 Protein phosphatase 2C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 362.0
HKD1_k127_1392218_113 Caulimovirus viroplasmin K03469,K06993 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 358.0
HKD1_k127_1392218_114 Protein of unknown function (DUF3867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 357.0
HKD1_k127_1392218_115 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 357.0
HKD1_k127_1392218_116 Sucrose-6F-phosphate phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 355.0
HKD1_k127_1392218_117 Peptidase, M50 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 351.0
HKD1_k127_1392218_118 Psort location Cytoplasmic, score - GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005506,GO:0006091,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009266,GO:0009268,GO:0009408,GO:0009409,GO:0009628,GO:0009636,GO:0009651,GO:0009987,GO:0010035,GO:0010446,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0016999,GO:0017001,GO:0017144,GO:0022900,GO:0033554,GO:0034599,GO:0034605,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070417,GO:0070482,GO:0070887,GO:0071214,GO:0071236,GO:0071453,GO:0071467,GO:0071469,GO:0071470,GO:0071472,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:0104004,GO:1901700,GO:1901701,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 346.0
HKD1_k127_1392218_119 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 342.0
HKD1_k127_1392218_12 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1030.0
HKD1_k127_1392218_120 DJ-1/PfpI family K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 332.0
HKD1_k127_1392218_121 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 330.0
HKD1_k127_1392218_122 Integral membrane protein (intg_mem_TP0381) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 329.0
HKD1_k127_1392218_123 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 327.0
HKD1_k127_1392218_124 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 325.0
HKD1_k127_1392218_125 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 325.0
HKD1_k127_1392218_126 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 325.0
HKD1_k127_1392218_127 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 317.0
HKD1_k127_1392218_128 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 311.0
HKD1_k127_1392218_129 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 306.0
HKD1_k127_1392218_13 Alpha-amylase domain K01176,K01187 - 3.2.1.1,3.2.1.20 0.0 1007.0
HKD1_k127_1392218_130 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 307.0
HKD1_k127_1392218_131 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 303.0
HKD1_k127_1392218_132 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 294.0
HKD1_k127_1392218_133 Phosphotransferase system, EIIC K20107,K20108 - 2.7.1.208 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 286.0
HKD1_k127_1392218_134 ECF-type riboflavin transporter, S component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 284.0
HKD1_k127_1392218_135 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000145 281.0
HKD1_k127_1392218_136 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 280.0
HKD1_k127_1392218_137 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 280.0
HKD1_k127_1392218_138 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 278.0
HKD1_k127_1392218_139 Tryptophan transporter TrpP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 282.0
HKD1_k127_1392218_14 Aminotransferase class I and II K09758 - 4.1.1.12 3.77e-321 987.0
HKD1_k127_1392218_140 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001987 274.0
HKD1_k127_1392218_141 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001134 274.0
HKD1_k127_1392218_142 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001879 267.0
HKD1_k127_1392218_143 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006555 267.0
HKD1_k127_1392218_144 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000354 262.0
HKD1_k127_1392218_145 Transcriptional regulator, MarR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001572 256.0
HKD1_k127_1392218_146 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003252 254.0
HKD1_k127_1392218_147 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000005223 241.0
HKD1_k127_1392218_148 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000005804 241.0
HKD1_k127_1392218_149 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000000000000000000000000000000007742 234.0
HKD1_k127_1392218_15 DNA helicase - - - 6.475e-319 983.0
HKD1_k127_1392218_150 Putative inner membrane exporter, YdcZ K09936 - - 0.00000000000000000000000000000000000000000000000000000000000001774 218.0
HKD1_k127_1392218_151 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000002437 218.0
HKD1_k127_1392218_152 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000003043 217.0
HKD1_k127_1392218_153 - - - - 0.0000000000000000000000000000000000000000000000000000000000001471 220.0
HKD1_k127_1392218_154 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000002154 215.0
HKD1_k127_1392218_155 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family - - - 0.00000000000000000000000000000000000000000000000000000003117 198.0
HKD1_k127_1392218_156 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000003501 198.0
HKD1_k127_1392218_157 C-C_Bond_Lyase of the TIM-Barrel fold - - - 0.000000000000000000000000000000000000000000000000000003702 203.0
HKD1_k127_1392218_158 - - - - 0.00000000000000000000000000000000000000000000000000000886 190.0
HKD1_k127_1392218_159 - - - - 0.00000000000000000000000000000000000000000000000000002567 189.0
HKD1_k127_1392218_16 Endoribonuclease that initiates mRNA decay K18682 - - 1.684e-303 934.0
HKD1_k127_1392218_160 - - - - 0.00000000000000000000000000000000000000000000000000003692 190.0
HKD1_k127_1392218_161 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000000000002529 184.0
HKD1_k127_1392218_162 LrgA family K06518 - - 0.0000000000000000000000000000000000000000000000007842 178.0
HKD1_k127_1392218_163 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000000000000001955 173.0
HKD1_k127_1392218_164 TSCPD domain - - - 0.00000000000000000000000000000000000000000000005104 169.0
HKD1_k127_1392218_165 Protein of unknown function (DUF1292) - - - 0.00000000000000000000000000000000000000000000005774 169.0
HKD1_k127_1392218_166 Control of competence regulator ComK, YlbF/YmcA - - - 0.000000000000000000000000000000000000000000000248 169.0
HKD1_k127_1392218_167 PRC-barrel domain - - - 0.0000000000000000000000000000000000000000000008189 166.0
HKD1_k127_1392218_168 Control of competence regulator ComK, YlbF/YmcA - - - 0.00000000000000000000000000000000000000000006597 162.0
HKD1_k127_1392218_169 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000005108 160.0
HKD1_k127_1392218_17 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.587e-295 908.0
HKD1_k127_1392218_170 TIGRFAM phage holin, LL-H - - - 0.0000000000000000000000000000000000000006756 149.0
HKD1_k127_1392218_171 - - - - 0.000000000000000000000000000000000000007715 146.0
HKD1_k127_1392218_172 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000000000000001726 145.0
HKD1_k127_1392218_173 Aminotransferase class IV K02619 - 4.1.3.38 0.000000000000000000000000000000000002695 147.0
HKD1_k127_1392218_174 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000000000000000003598 136.0
HKD1_k127_1392218_175 Cold shock protein K03704 - - 0.00000000000000000000000000000000008387 133.0
HKD1_k127_1392218_177 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000008099 130.0
HKD1_k127_1392218_178 Transcriptional regulator - - - 0.00000000000000000000000000000005068 133.0
HKD1_k127_1392218_179 - - - - 0.000000000000000000000000000001434 123.0
HKD1_k127_1392218_18 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 8.999e-275 847.0
HKD1_k127_1392218_180 4Fe-4S dicluster domain - - - 0.000000000000000000000000002013 112.0
HKD1_k127_1392218_181 - - - - 0.0000000000000000000000009251 109.0
HKD1_k127_1392218_182 - - - - 0.000000000000000000000005857 104.0
HKD1_k127_1392218_183 - K03537 - 3.1.26.5 0.00000000000000000000005509 100.0
HKD1_k127_1392218_185 Sporulation protein YtfJ - - - 0.00000000000000007723 85.0
HKD1_k127_1392218_187 - - - - 0.000000002053 58.0
HKD1_k127_1392218_189 helix_turn_helix, mercury resistance - - - 0.00003723 46.0
HKD1_k127_1392218_19 Putative component of 'biosynthetic module' - - - 1.004e-271 842.0
HKD1_k127_1392218_2 HELICc2 K03722 - 3.6.4.12 0.0 1551.0
HKD1_k127_1392218_20 COG COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 1.441e-262 814.0
HKD1_k127_1392218_21 Na+/H+ antiporter family K03315 - - 3.803e-260 807.0
HKD1_k127_1392218_22 Histidinol phosphatase and related hydrolases of the PHP family - - - 1.566e-257 799.0
HKD1_k127_1392218_23 Anthranilate synthase component I, N terminal region K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 1.998e-255 792.0
HKD1_k127_1392218_24 FAD dependent oxidoreductase - - - 1.84e-254 787.0
HKD1_k127_1392218_25 Aminotransferase K00812 - 2.6.1.1 1.626e-253 783.0
HKD1_k127_1392218_26 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.363e-236 734.0
HKD1_k127_1392218_27 Orn/Lys/Arg decarboxylase, C-terminal domain K01585 - 4.1.1.19 6.733e-236 737.0
HKD1_k127_1392218_28 Putative amidase domain - - - 2.472e-227 707.0
HKD1_k127_1392218_29 - - - - 3.671e-224 702.0
HKD1_k127_1392218_3 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1330.0
HKD1_k127_1392218_30 Belongs to the peptidase M16 family - - - 3.849e-224 699.0
HKD1_k127_1392218_31 Src homology 3 domains - - - 5.637e-224 705.0
HKD1_k127_1392218_32 Belongs to the ABC transporter superfamily K10112 - - 9.143e-223 693.0
HKD1_k127_1392218_33 Orn/Lys/Arg decarboxylase, C-terminal domain K01585 - 4.1.1.19 3.12e-219 689.0
HKD1_k127_1392218_34 Belongs to the CinA family K03742,K03743 - 3.5.1.42 4.414e-219 684.0
HKD1_k127_1392218_35 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 2.18e-217 678.0
HKD1_k127_1392218_36 Tetratricopeptide repeat - - - 3.443e-217 681.0
HKD1_k127_1392218_37 ACT domain K00928 - 2.7.2.4 3.129e-216 676.0
HKD1_k127_1392218_38 G5 K18346 - - 9.102e-215 677.0
HKD1_k127_1392218_39 Phosphotransferase system, EIIC K20107,K20108 - 2.7.1.208 1.133e-214 670.0
HKD1_k127_1392218_4 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.0 1299.0
HKD1_k127_1392218_40 Sporulation integral membrane protein YlbJ - - - 1.486e-210 662.0
HKD1_k127_1392218_41 Penicillin-binding protein 5, C-terminal domain K07258 - 3.4.16.4 1.23e-208 652.0
HKD1_k127_1392218_42 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 4.349e-208 648.0
HKD1_k127_1392218_43 Toxic anion resistance protein (TelA) - - - 1.323e-206 646.0
HKD1_k127_1392218_44 Natural resistance-associated macrophage protein - - - 8.067e-206 646.0
HKD1_k127_1392218_45 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.657e-205 645.0
HKD1_k127_1392218_46 Monogalactosyldiacylglycerol synthase K03429 - 2.4.1.315 2.557e-205 642.0
HKD1_k127_1392218_47 Phosphoribosyl transferase - - - 3.751e-201 631.0
HKD1_k127_1392218_48 NIF3 (NGG1p interacting factor 3) - - - 4.219e-200 627.0
HKD1_k127_1392218_49 M42 glutamyl aminopeptidase - - - 3.219e-197 617.0
HKD1_k127_1392218_5 Glutamate--ammonia ligase, catalytic domain protein K01915 - 6.3.1.2 0.0 1148.0
HKD1_k127_1392218_50 Participates in both transcription termination and antitermination K02600 - - 1.182e-194 610.0
HKD1_k127_1392218_51 radical SAM protein, TIGR01212 family K07139 - - 1.927e-194 607.0
HKD1_k127_1392218_52 WG containing repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 602.0
HKD1_k127_1392218_53 PELOTA RNA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 592.0
HKD1_k127_1392218_54 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 576.0
HKD1_k127_1392218_55 MATE efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 584.0
HKD1_k127_1392218_56 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 582.0
HKD1_k127_1392218_57 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 572.0
HKD1_k127_1392218_58 Rhodanese Homology Domain K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 570.0
HKD1_k127_1392218_59 VanW like protein K18346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 572.0
HKD1_k127_1392218_6 ABC transporter C-terminal domain K15738 - - 0.0 1130.0
HKD1_k127_1392218_60 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 561.0
HKD1_k127_1392218_61 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 567.0
HKD1_k127_1392218_62 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 553.0
HKD1_k127_1392218_63 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 550.0
HKD1_k127_1392218_64 DHHA1 domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 546.0
HKD1_k127_1392218_65 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 539.0
HKD1_k127_1392218_66 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 514.0
HKD1_k127_1392218_67 Phosphotransferase system, EIIC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 516.0
HKD1_k127_1392218_68 delta-lactam-biosynthetic de-N-acetylase K01567 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 511.0
HKD1_k127_1392218_69 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 512.0
HKD1_k127_1392218_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0 1088.0
HKD1_k127_1392218_70 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 508.0
HKD1_k127_1392218_71 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 510.0
HKD1_k127_1392218_72 DAHP synthetase I family K01626,K03856,K13853 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 501.0
HKD1_k127_1392218_73 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 499.0
HKD1_k127_1392218_74 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 499.0
HKD1_k127_1392218_75 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 492.0
HKD1_k127_1392218_76 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 491.0
HKD1_k127_1392218_77 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 486.0
HKD1_k127_1392218_78 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 480.0
HKD1_k127_1392218_79 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 480.0
HKD1_k127_1392218_8 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.0 1067.0
HKD1_k127_1392218_80 Exonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 477.0
HKD1_k127_1392218_81 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 471.0
HKD1_k127_1392218_82 Belongs to the pyridoxine kinase family K00868 - 2.7.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 471.0
HKD1_k127_1392218_83 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 467.0
HKD1_k127_1392218_84 CAP-associated N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 467.0
HKD1_k127_1392218_85 Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 464.0
HKD1_k127_1392218_86 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 463.0
HKD1_k127_1392218_87 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 463.0
HKD1_k127_1392218_88 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 460.0
HKD1_k127_1392218_89 Transporter, small conductance mechanosensitive ion channel MscS family protein K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 459.0
HKD1_k127_1392218_9 ABC-2 type transporter K01421 - - 0.0 1058.0
HKD1_k127_1392218_90 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 443.0
HKD1_k127_1392218_91 peptidyl-prolyl isomerase K03769,K07533 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000943 441.0
HKD1_k127_1392218_92 Endonuclease/Exonuclease/phosphatase family K06896 - 3.1.3.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 435.0
HKD1_k127_1392218_93 Clp protease K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008138 433.0
HKD1_k127_1392218_94 transcriptional regulator, MerR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 428.0
HKD1_k127_1392218_95 Iron/manganese superoxide dismutases, alpha-hairpin domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 422.0
HKD1_k127_1392218_96 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 414.0
HKD1_k127_1392218_97 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 407.0
HKD1_k127_1392218_98 ABC transporter, ATP-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 394.0
HKD1_k127_1392218_99 GHKL domain K07706 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 398.0
HKD1_k127_1410008_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 3.603e-306 943.0
HKD1_k127_1410008_1 Monogalactosyldiacylglycerol synthase K03429 - 2.4.1.315 3.194e-224 698.0
HKD1_k127_1410008_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 388.0
HKD1_k127_1410008_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000000000000002425 210.0
HKD1_k127_1410008_4 Glutaredoxin - - - 0.0000000000000000000000000000001169 125.0
HKD1_k127_1410008_5 - - - - 0.0000000000000000000005473 96.0
HKD1_k127_1489903_0 FtsX-like permease family K02004 - - 0.0 1647.0
HKD1_k127_1489903_1 Putative exonuclease SbcCD, C subunit K03546 - - 0.0 1604.0
HKD1_k127_1489903_10 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 602.0
HKD1_k127_1489903_11 Alanine racemase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 593.0
HKD1_k127_1489903_12 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 559.0
HKD1_k127_1489903_13 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 545.0
HKD1_k127_1489903_14 Alpha beta K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 520.0
HKD1_k127_1489903_15 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 499.0
HKD1_k127_1489903_16 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 500.0
HKD1_k127_1489903_17 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 494.0
HKD1_k127_1489903_18 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 432.0
HKD1_k127_1489903_19 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 431.0
HKD1_k127_1489903_2 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.0 1287.0
HKD1_k127_1489903_20 Psort location CytoplasmicMembrane, score K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 418.0
HKD1_k127_1489903_21 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 417.0
HKD1_k127_1489903_22 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 415.0
HKD1_k127_1489903_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 407.0
HKD1_k127_1489903_24 ABC transporter (Permease) K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 402.0
HKD1_k127_1489903_25 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 375.0
HKD1_k127_1489903_26 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 355.0
HKD1_k127_1489903_27 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 356.0
HKD1_k127_1489903_28 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01034 - 2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 347.0
HKD1_k127_1489903_29 3-oxoacid CoA-transferase, B subunit K01035 - 2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 342.0
HKD1_k127_1489903_3 MutS domain III - - - 2.798e-284 880.0
HKD1_k127_1489903_30 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 337.0
HKD1_k127_1489903_31 transcriptional regulator TetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 331.0
HKD1_k127_1489903_32 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009306 339.0
HKD1_k127_1489903_33 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 304.0
HKD1_k127_1489903_34 YARHG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 302.0
HKD1_k127_1489903_35 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003834 278.0
HKD1_k127_1489903_36 diguanylate cyclase K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005676 291.0
HKD1_k127_1489903_38 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000003631 235.0
HKD1_k127_1489903_39 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000001156 201.0
HKD1_k127_1489903_4 Putative modulator of DNA gyrase K03568 - - 1.309e-279 862.0
HKD1_k127_1489903_40 - - - - 0.000000000000000000000000000000000000000000000000002039 186.0
HKD1_k127_1489903_42 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02009 - - 0.0000000000000000000000000000000000000001079 152.0
HKD1_k127_1489903_43 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000117 137.0
HKD1_k127_1489903_44 Histidine kinase - - - 0.0000000000000000000000000000003611 126.0
HKD1_k127_1489903_45 - - - - 0.0000000000000000000000000002137 118.0
HKD1_k127_1489903_46 - - - - 0.0000000000000000000009911 102.0
HKD1_k127_1489903_47 - - - - 0.0000000000000000002629 88.0
HKD1_k127_1489903_48 - - - - 0.00000000000000002089 82.0
HKD1_k127_1489903_49 Protein of unknown function (DUF3021) - - - 0.00000000001275 70.0
HKD1_k127_1489903_5 Putative modulator of DNA gyrase K03592 - - 2.335e-257 797.0
HKD1_k127_1489903_6 MATE efflux family protein - - - 1.533e-245 764.0
HKD1_k127_1489903_7 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 3.828e-229 713.0
HKD1_k127_1489903_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07651 - 2.7.13.3 1.292e-227 712.0
HKD1_k127_1489903_9 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) K07862 - - 4.32e-217 678.0
HKD1_k127_150153_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.227e-319 986.0
HKD1_k127_150153_1 Iron-only hydrogenase maturation rSAM protein HydG K03150 - 4.1.99.19 8.377e-249 773.0
HKD1_k127_150153_10 UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 304.0
HKD1_k127_150153_11 IclR helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003379 239.0
HKD1_k127_150153_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004495 240.0
HKD1_k127_150153_13 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000002232 218.0
HKD1_k127_150153_14 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000001692 192.0
HKD1_k127_150153_15 - - - - 0.0000000000000000000000000000000000000000000000000001157 191.0
HKD1_k127_150153_16 Transcriptional regulator K13771 - - 0.000000000000000000000000000000000000000000000000001484 185.0
HKD1_k127_150153_17 Iron-only hydrogenase system regulator - - - 0.000000000000000000000000000000000003668 138.0
HKD1_k127_150153_18 - - - - 0.000000000000000000000000000004882 119.0
HKD1_k127_150153_19 Mut7-C ubiquitin K03154 - - 0.0000000000000000000001359 98.0
HKD1_k127_150153_2 maturation GTPase HydF - - - 3.999e-203 638.0
HKD1_k127_150153_21 PrcB C-terminal - - - 0.000002179 59.0
HKD1_k127_150153_3 Iron-only hydrogenase maturation rSAM protein HydE K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 552.0
HKD1_k127_150153_4 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 505.0
HKD1_k127_150153_5 Extradiol ring-cleavage dioxygenase class III protein subunit B K06990,K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 490.0
HKD1_k127_150153_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 487.0
HKD1_k127_150153_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 410.0
HKD1_k127_150153_8 Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 348.0
HKD1_k127_150153_9 Domain of unknown function (DUF4163) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 344.0
HKD1_k127_1542743_0 Amino acid permease - - - 1.974e-253 789.0
HKD1_k127_1542743_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 482.0
HKD1_k127_1542743_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 426.0
HKD1_k127_1542743_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006755 258.0
HKD1_k127_1542743_4 CBS domain - - - 0.00000000000000000000000000000000000000000000002726 174.0
HKD1_k127_1542743_5 - - - - 0.0000000000000000000000000000000000000007621 152.0
HKD1_k127_1542743_6 the major facilitator superfamily - - - 0.0000000000000000000000000000001647 130.0
HKD1_k127_1542743_7 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000704 122.0
HKD1_k127_1542743_8 Domain of Unknown Function (DUF1540) - - - 0.0000000000000000000000004343 104.0
HKD1_k127_1565643_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1059.0
HKD1_k127_1565643_1 Belongs to the glycosyl hydrolase 1 family K01223 - 3.2.1.86 5.174e-292 898.0
HKD1_k127_1565643_10 NUBPL iron-transfer P-loop NTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 353.0
HKD1_k127_1565643_11 COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 376.0
HKD1_k127_1565643_12 ABC transporter K05833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 287.0
HKD1_k127_1565643_13 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001455 285.0
HKD1_k127_1565643_14 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001983 250.0
HKD1_k127_1565643_15 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000002895 199.0
HKD1_k127_1565643_16 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000003873 171.0
HKD1_k127_1565643_17 Sugar (and other) transporter - - - 0.00000000000001146 74.0
HKD1_k127_1565643_18 Pectinesterase - - - 0.000001055 62.0
HKD1_k127_1565643_19 Subtilase family K13274,K14645 - - 0.000001834 61.0
HKD1_k127_1565643_2 CoA-binding domain - - - 2.089e-269 842.0
HKD1_k127_1565643_20 Phospholipase, patatin family - - - 0.00006179 45.0
HKD1_k127_1565643_21 Protein of unknown function (DUF1659) - - - 0.00007302 46.0
HKD1_k127_1565643_22 NUBPL iron-transfer P-loop NTPase - - - 0.000215 44.0
HKD1_k127_1565643_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102,K11103 - - 4.354e-216 680.0
HKD1_k127_1565643_4 ABC transporter K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 565.0
HKD1_k127_1565643_5 Belongs to the binding-protein-dependent transport system permease family K05832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 499.0
HKD1_k127_1565643_6 Protein of unknown function (DUF445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 463.0
HKD1_k127_1565643_7 binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 391.0
HKD1_k127_1565643_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 373.0
HKD1_k127_1565643_9 biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 357.0
HKD1_k127_157103_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.0 1179.0
HKD1_k127_157103_1 GTP-binding protein K06207 - - 0.0 1178.0
HKD1_k127_157103_10 hmm pf02632 K03523 - - 0.000000000000000000000000000000000000000000000000000000000000005726 221.0
HKD1_k127_157103_11 Bacterial SH3 domain - - - 0.0000000000000000000000000000008385 134.0
HKD1_k127_157103_12 - - - - 0.000000000000000000000000000003619 119.0
HKD1_k127_157103_13 - - - - 0.00000000000000000004784 92.0
HKD1_k127_157103_2 Threonine synthase N terminus K01733 - 4.2.3.1 1.173e-227 715.0
HKD1_k127_157103_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 595.0
HKD1_k127_157103_4 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 538.0
HKD1_k127_157103_5 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 356.0
HKD1_k127_157103_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 348.0
HKD1_k127_157103_7 2'-5' RNA ligase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007524 272.0
HKD1_k127_157103_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000126 254.0
HKD1_k127_157103_9 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000004647 221.0
HKD1_k127_158601_0 belongs to the iron- containing alcohol dehydrogenase family K04072 - 1.1.1.1,1.2.1.10 0.0 1033.0
HKD1_k127_158601_1 DHHA2 K15986 - 3.6.1.1 5.007e-293 905.0
HKD1_k127_158601_2 Protein of unknown function (DUF4230) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 318.0
HKD1_k127_159110_1 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.00011 53.0
HKD1_k127_1904283_0 Peptidase, U32 family K08303 - - 0.0 1452.0
HKD1_k127_1904283_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0 1427.0
HKD1_k127_1904283_10 Potassium uptake protein K03498 - - 4.444e-229 715.0
HKD1_k127_1904283_11 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 2.772e-209 651.0
HKD1_k127_1904283_12 Helix-turn-helix XRE-family like proteins - - - 2.687e-204 640.0
HKD1_k127_1904283_13 Glutaminase K01425 - 3.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 576.0
HKD1_k127_1904283_14 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 575.0
HKD1_k127_1904283_15 G5 K18346 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 582.0
HKD1_k127_1904283_16 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 569.0
HKD1_k127_1904283_17 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 521.0
HKD1_k127_1904283_18 EDD domain protein, DegV family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 516.0
HKD1_k127_1904283_19 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 511.0
HKD1_k127_1904283_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0 1378.0
HKD1_k127_1904283_20 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 511.0
HKD1_k127_1904283_21 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 507.0
HKD1_k127_1904283_22 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 472.0
HKD1_k127_1904283_23 TrkA N-terminal domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 432.0
HKD1_k127_1904283_24 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 436.0
HKD1_k127_1904283_25 YtxC-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 374.0
HKD1_k127_1904283_26 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 370.0
HKD1_k127_1904283_27 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 334.0
HKD1_k127_1904283_28 domain protein K06951 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 326.0
HKD1_k127_1904283_29 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 319.0
HKD1_k127_1904283_3 AAA domain K04076 - 3.4.21.53 0.0 1296.0
HKD1_k127_1904283_30 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 316.0
HKD1_k127_1904283_31 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 304.0
HKD1_k127_1904283_32 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 284.0
HKD1_k127_1904283_33 Endodeoxyribonuclease RusA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001974 263.0
HKD1_k127_1904283_34 Protein of unknown function (DUF523) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002185 254.0
HKD1_k127_1904283_35 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000000000000000005079 226.0
HKD1_k127_1904283_36 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000000000000000000000000000000000005488 226.0
HKD1_k127_1904283_37 - - - - 0.00000000000000000000000000000007185 124.0
HKD1_k127_1904283_38 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000000003805 119.0
HKD1_k127_1904283_39 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000003196 117.0
HKD1_k127_1904283_4 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1247.0
HKD1_k127_1904283_40 repeat protein - - - 0.000000000000000000000002501 102.0
HKD1_k127_1904283_5 Protein of unknown function (DUF4080) K04034 - 1.21.98.3 0.0 1094.0
HKD1_k127_1904283_6 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0 1083.0
HKD1_k127_1904283_7 ABC transporter K02056 - 3.6.3.17 1.079e-309 952.0
HKD1_k127_1904283_8 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.231e-288 887.0
HKD1_k127_1904283_9 Dipeptidase K01270 - - 4.002e-266 824.0
HKD1_k127_2107328_0 ABC transporter transmembrane region K06147 - - 0.0 1195.0
HKD1_k127_2107328_1 Sigma-54 interaction domain - - - 0.0 1048.0
HKD1_k127_2107328_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007077 288.0
HKD1_k127_2107328_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000715 249.0
HKD1_k127_2107328_12 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001287 253.0
HKD1_k127_2107328_13 Uncharacterized BCR, YaiI/YqxD family COG1671 K09768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004068 245.0
HKD1_k127_2107328_14 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000000000000000000000000000000000000000000002941 234.0
HKD1_k127_2107328_15 NusG domain II K00805 - 2.5.1.30 0.00000000000000000000000000000000000000000000000001475 182.0
HKD1_k127_2107328_16 protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity - - - 0.00000000000000000000000000000000000001026 146.0
HKD1_k127_2107328_17 - - - - 0.00000000000000000001046 92.0
HKD1_k127_2107328_2 ABC transporter K06147 - - 2.5e-323 996.0
HKD1_k127_2107328_3 Sodium:dicarboxylate symporter family K06956 - - 3.001e-221 693.0
HKD1_k127_2107328_4 Methyltransferase domain - - - 2.39e-218 680.0
HKD1_k127_2107328_5 Na+/H+ antiporter family K03315 - - 9.92e-198 625.0
HKD1_k127_2107328_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 499.0
HKD1_k127_2107328_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 387.0
HKD1_k127_2107328_8 Bacterial SH3 domain homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 390.0
HKD1_k127_2107328_9 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 286.0
HKD1_k127_2108901_0 ABC transporter - - - 0.0 1053.0
HKD1_k127_2108901_1 Ethanolamine utilisation protein, EutH K04023 - - 4.7e-215 670.0
HKD1_k127_2108901_10 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 368.0
HKD1_k127_2108901_11 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 304.0
HKD1_k127_2108901_12 BMC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 300.0
HKD1_k127_2108901_13 Involved in chromosome partitioning - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 285.0
HKD1_k127_2108901_14 ethanolamine K04030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001219 279.0
HKD1_k127_2108901_15 QueT transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003964 269.0
HKD1_k127_2108901_16 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000000000000000000001366 249.0
HKD1_k127_2108901_17 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003272 249.0
HKD1_k127_2108901_18 BMC domain K04027 - - 0.00000000000000000000000000000000000000000000001051 172.0
HKD1_k127_2108901_19 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000000000000000000000009296 134.0
HKD1_k127_2108901_2 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 581.0
HKD1_k127_2108901_21 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) - - - 0.00000000000000000000000007054 107.0
HKD1_k127_2108901_24 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000168 59.0
HKD1_k127_2108901_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 533.0
HKD1_k127_2108901_4 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 503.0
HKD1_k127_2108901_5 Cobalamin adenosyltransferase K04032 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 479.0
HKD1_k127_2108901_6 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 457.0
HKD1_k127_2108901_7 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 390.0
HKD1_k127_2108901_8 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 382.0
HKD1_k127_2108901_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000775 366.0
HKD1_k127_2154531_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1474.0
HKD1_k127_2154531_1 penicillin-binding protein K03587,K08384 - 3.4.16.4 0.0 1215.0
HKD1_k127_2154531_10 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.116e-261 809.0
HKD1_k127_2154531_11 Peptidase M16 inactive domain protein - - - 1.623e-259 802.0
HKD1_k127_2154531_12 Protein of unknown function (DUF512) - - - 2.21e-258 799.0
HKD1_k127_2154531_13 Psort location Cytoplasmic, score K17810 - 6.3.1.12 5.426e-257 793.0
HKD1_k127_2154531_14 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 1.719e-243 759.0
HKD1_k127_2154531_15 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 1.63e-242 754.0
HKD1_k127_2154531_16 Peptidase M16 inactive domain protein - - - 3.886e-241 748.0
HKD1_k127_2154531_17 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 2.207e-237 738.0
HKD1_k127_2154531_18 ATPase histidine kinase DNA gyrase B HSP90 domain protein K07636 - 2.7.13.3 7.264e-229 713.0
HKD1_k127_2154531_19 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 8.24e-229 712.0
HKD1_k127_2154531_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 K04041 - 3.1.3.11 0.0 1177.0
HKD1_k127_2154531_20 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1.495e-222 692.0
HKD1_k127_2154531_21 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 9.538e-218 678.0
HKD1_k127_2154531_22 Belongs to the SEDS family K03588 - - 3.894e-201 630.0
HKD1_k127_2154531_23 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 3.861e-198 619.0
HKD1_k127_2154531_24 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 589.0
HKD1_k127_2154531_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 584.0
HKD1_k127_2154531_26 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 581.0
HKD1_k127_2154531_27 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 489.0
HKD1_k127_2154531_28 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 477.0
HKD1_k127_2154531_29 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR K06383 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 471.0
HKD1_k127_2154531_3 pts system K20116,K20117,K20118 - 2.7.1.199 7.405e-306 942.0
HKD1_k127_2154531_30 transcriptional antiterminator K03488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 461.0
HKD1_k127_2154531_31 YIEGIA protein K05739 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 450.0
HKD1_k127_2154531_32 YIEGIA protein K05739 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 450.0
HKD1_k127_2154531_33 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 432.0
HKD1_k127_2154531_34 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 427.0
HKD1_k127_2154531_35 response regulator K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 420.0
HKD1_k127_2154531_36 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 419.0
HKD1_k127_2154531_37 LytTr DNA-binding domain K02477,K07705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 394.0
HKD1_k127_2154531_38 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 360.0
HKD1_k127_2154531_39 Essential cell division protein K03589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 350.0
HKD1_k127_2154531_4 ATPase. Has a role at an early stage in the morphogenesis of the spore coat K06398 GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 1.131e-291 898.0
HKD1_k127_2154531_40 Bacterial protein of unknown function (DUF881) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 332.0
HKD1_k127_2154531_41 Bacterial protein of unknown function (DUF881) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 331.0
HKD1_k127_2154531_42 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 321.0
HKD1_k127_2154531_43 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 295.0
HKD1_k127_2154531_44 Accessory gene regulator B K07813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007631 277.0
HKD1_k127_2154531_45 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 K02777,K20116,K20117,K20118 - 2.7.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000612 268.0
HKD1_k127_2154531_46 Protein of unknown function (DUF1290) - - - 0.0000000000000000000000000000000000000000000000000000000000001201 213.0
HKD1_k127_2154531_47 - - - - 0.000000000000000000000000000000000000000000000003273 177.0
HKD1_k127_2154531_48 PRC-barrel domain - - - 0.00000000000000000000000000000000000000000000001158 171.0
HKD1_k127_2154531_49 - - - - 0.0000000000000000000000000000000000000000001052 162.0
HKD1_k127_2154531_5 5TMR of 5TMR-LYT K02478,K07704 - 2.7.13.3 3.518e-289 894.0
HKD1_k127_2154531_50 - - - - 0.0000000000000000000000000000001037 124.0
HKD1_k127_2154531_52 transcriptional regulator (AraC family) - - - 0.00001032 50.0
HKD1_k127_2154531_6 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 6.691e-288 887.0
HKD1_k127_2154531_7 Carbon starvation protein CstA - - - 7.488e-281 867.0
HKD1_k127_2154531_8 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.278e-278 857.0
HKD1_k127_2154531_9 HD domain - - - 7.326e-277 859.0
HKD1_k127_2199707_0 Aminotransferase class I and II K10206 - 2.6.1.83 2.475e-229 715.0
HKD1_k127_2199707_1 His Kinase A (phosphoacceptor) domain K18345 - 2.7.13.3 9.668e-221 689.0
HKD1_k127_2199707_10 Predicted permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005976 248.0
HKD1_k127_2199707_11 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004124 244.0
HKD1_k127_2199707_12 Predicted permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005188 242.0
HKD1_k127_2199707_13 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000000000000000000000000000000000255 207.0
HKD1_k127_2199707_14 Transcriptional regulatory protein, C terminal K18344 - - 0.000000000000000000000000000000000000000000000000000000009368 206.0
HKD1_k127_2199707_15 Copper-exporting ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000001636 135.0
HKD1_k127_2199707_16 - - - - 0.000000000000000000000007601 102.0
HKD1_k127_2199707_17 Aminotransferase class-V - - - 0.0000000000000000001653 89.0
HKD1_k127_2199707_18 Aminotransferase class-V - - - 0.0000000000000001861 84.0
HKD1_k127_2199707_2 helicase superfamily c-terminal domain - - - 3.303e-213 666.0
HKD1_k127_2199707_3 homoserine dehydrogenase K00003 - 1.1.1.3 1.763e-197 621.0
HKD1_k127_2199707_4 C4-dicarboxylate anaerobic carrier - - - 5.374e-196 620.0
HKD1_k127_2199707_5 Belongs to the LDH MDH superfamily. LDH family K00016 - 1.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 550.0
HKD1_k127_2199707_6 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 542.0
HKD1_k127_2199707_7 Domain of unknown function (DUF4438) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 522.0
HKD1_k127_2199707_8 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 488.0
HKD1_k127_2199707_9 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 338.0
HKD1_k127_2199888_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1596.0
HKD1_k127_2199888_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0 1056.0
HKD1_k127_2199888_10 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001267 233.0
HKD1_k127_2199888_12 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000004756 198.0
HKD1_k127_2199888_13 acid phosphatase activity K01727 - 4.2.2.1 0.0000000000000000000000000000000000000000000000000001007 195.0
HKD1_k127_2199888_14 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000000000000000000000000000000000001304 178.0
HKD1_k127_2199888_15 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000000001852 153.0
HKD1_k127_2199888_17 Mitochondrial biogenesis AIM24 - - - 0.0000000000000007364 80.0
HKD1_k127_2199888_18 - - - - 0.000000000000008611 83.0
HKD1_k127_2199888_19 Helix-turn-helix domain K07483 - - 0.0004217 42.0
HKD1_k127_2199888_2 OPT oligopeptide transporter protein - - - 0.0 1038.0
HKD1_k127_2199888_3 Aluminum resistance protein - - - 4.241e-269 829.0
HKD1_k127_2199888_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 548.0
HKD1_k127_2199888_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 470.0
HKD1_k127_2199888_6 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 454.0
HKD1_k127_2199888_7 - K16788 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 293.0
HKD1_k127_2199888_8 3H domain K07105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 290.0
HKD1_k127_226738_0 Belongs to the glycosyl hydrolase 13 family K00705 - 2.4.1.25 5.759e-287 884.0
HKD1_k127_226738_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 2.373e-245 759.0
HKD1_k127_243659_0 Putative Fe-S cluster - - - 4.156e-288 893.0
HKD1_k127_243659_1 Sigma factor PP2C-like phosphatases - - - 3.042e-219 683.0
HKD1_k127_243659_10 Nuclease-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 323.0
HKD1_k127_243659_11 DNA sulfur modification protein DndD K19171 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 326.0
HKD1_k127_243659_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 296.0
HKD1_k127_243659_13 ABC transporter permease K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 287.0
HKD1_k127_243659_14 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000336 272.0
HKD1_k127_243659_15 3' exoribonuclease, RNase T-like K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 261.0
HKD1_k127_243659_16 Scavenger mRNA decapping enzyme C-term binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000001605 236.0
HKD1_k127_243659_17 NADH ubiquinone oxidoreductase 24 kD subunit - - - 0.000000000000000000000000000000000001139 139.0
HKD1_k127_243659_19 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000000000000006252 113.0
HKD1_k127_243659_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 2.302e-217 679.0
HKD1_k127_243659_20 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000009973 88.0
HKD1_k127_243659_21 HPr family K11189 - - 0.00000002423 58.0
HKD1_k127_243659_3 Diguanylate cyclase - - - 3.326e-207 666.0
HKD1_k127_243659_4 Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 565.0
HKD1_k127_243659_5 Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 483.0
HKD1_k127_243659_6 Sulfurtransferase DndC K19170 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 475.0
HKD1_k127_243659_7 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 408.0
HKD1_k127_243659_8 ABC transporter K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 367.0
HKD1_k127_243659_9 ABC transporter substrate-binding protein K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 356.0
HKD1_k127_2567078_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1390.0
HKD1_k127_2567078_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1268.0
HKD1_k127_2567078_10 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 1.312e-239 745.0
HKD1_k127_2567078_11 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.171e-231 719.0
HKD1_k127_2567078_12 Sodium:dicarboxylate symporter family - - - 1.461e-231 721.0
HKD1_k127_2567078_13 Glucose-1-phosphate adenylyltransferase, GlgD subunit K00975 - 2.7.7.27 9.965e-211 658.0
HKD1_k127_2567078_14 malic enzyme K00027 - 1.1.1.38 9.556e-210 657.0
HKD1_k127_2567078_15 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 - 2.7.7.7 6.848e-205 640.0
HKD1_k127_2567078_16 Bacterial extracellular solute-binding protein K11069 - - 4.621e-203 634.0
HKD1_k127_2567078_17 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 8.137e-201 627.0
HKD1_k127_2567078_18 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 3.295e-200 626.0
HKD1_k127_2567078_19 Aminotransferase class-V - - - 7.149e-198 621.0
HKD1_k127_2567078_2 Radical SAM N-terminal - - - 0.0 1193.0
HKD1_k127_2567078_20 Psort location CytoplasmicMembrane, score - - - 9.423e-194 608.0
HKD1_k127_2567078_21 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 598.0
HKD1_k127_2567078_22 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 586.0
HKD1_k127_2567078_23 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 573.0
HKD1_k127_2567078_24 S1 domain K00243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 532.0
HKD1_k127_2567078_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 491.0
HKD1_k127_2567078_26 ABC transporter permease K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 489.0
HKD1_k127_2567078_27 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 480.0
HKD1_k127_2567078_28 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 476.0
HKD1_k127_2567078_29 spermidine putrescine transport system, permease K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 436.0
HKD1_k127_2567078_3 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.0 1084.0
HKD1_k127_2567078_30 DNA polymerase alpha chain like domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 431.0
HKD1_k127_2567078_31 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 429.0
HKD1_k127_2567078_32 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 426.0
HKD1_k127_2567078_33 Belongs to the ABC transporter superfamily K10823 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 406.0
HKD1_k127_2567078_34 Belongs to the SfsA family K06206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 379.0
HKD1_k127_2567078_35 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 377.0
HKD1_k127_2567078_36 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 372.0
HKD1_k127_2567078_37 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 351.0
HKD1_k127_2567078_38 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 319.0
HKD1_k127_2567078_39 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 303.0
HKD1_k127_2567078_4 Alpha-amylase domain K00705 - 2.4.1.25 0.0 1052.0
HKD1_k127_2567078_40 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000142 258.0
HKD1_k127_2567078_41 Abc transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005921 262.0
HKD1_k127_2567078_42 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000008957 221.0
HKD1_k127_2567078_43 Fumarate K01676,K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000267 222.0
HKD1_k127_2567078_44 - - - - 0.00000000000000000000000000000000000000000000000000000003057 198.0
HKD1_k127_2567078_45 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000000000000000000000000000000001194 192.0
HKD1_k127_2567078_46 PFAM Integrase catalytic region - - - 0.00000000000000000000000000000000000000000000002397 171.0
HKD1_k127_2567078_47 - - - - 0.0000000000000000000000000000000000000000000002057 169.0
HKD1_k127_2567078_48 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000002685 166.0
HKD1_k127_2567078_49 - - - - 0.000000000000000000000000000002465 120.0
HKD1_k127_2567078_5 peptidase M24 K01262 - 3.4.11.9 0.0 1042.0
HKD1_k127_2567078_50 Domain of unknown function (DUF378) K09779 - - 0.000000000000000000000003774 103.0
HKD1_k127_2567078_51 MatE - - - 0.00000000001446 66.0
HKD1_k127_2567078_52 Thioesterase superfamily - - - 0.00008874 46.0
HKD1_k127_2567078_53 - - - - 0.0001172 44.0
HKD1_k127_2567078_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0 1019.0
HKD1_k127_2567078_7 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 8.25e-322 989.0
HKD1_k127_2567078_8 Domain of unknown function (DUF1846) - - - 8.409e-313 960.0
HKD1_k127_2567078_9 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.963e-282 871.0
HKD1_k127_2567278_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0 1009.0
HKD1_k127_2567278_1 Psort location Cytoplasmic, score K00111 - 1.1.5.3 2.233e-271 839.0
HKD1_k127_2567278_10 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 424.0
HKD1_k127_2567278_11 oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 425.0
HKD1_k127_2567278_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 376.0
HKD1_k127_2567278_13 Putative rRNA methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 340.0
HKD1_k127_2567278_14 Glycerol-3-phosphate responsive antiterminator K02443 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 329.0
HKD1_k127_2567278_15 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 282.0
HKD1_k127_2567278_16 Voltage-dependent anion channel K11041 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002366 261.0
HKD1_k127_2567278_17 Protein of unknown function (DUF1667) - - - 0.00000000000000000000000000000000000000000000000000000000003443 206.0
HKD1_k127_2567278_18 - - - - 0.0000000000000000000000000000000000000000000000000000000002807 204.0
HKD1_k127_2567278_19 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000007399 175.0
HKD1_k127_2567278_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 7.719e-236 734.0
HKD1_k127_2567278_20 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000000000000000005055 122.0
HKD1_k127_2567278_21 - - - - 0.0000009587 55.0
HKD1_k127_2567278_22 PFAM small acid-soluble spore protein alpha beta type K06421 - - 0.0001689 46.0
HKD1_k127_2567278_3 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 2.051e-221 689.0
HKD1_k127_2567278_4 His Kinase A (phosphoacceptor) domain - - - 1.899e-194 626.0
HKD1_k127_2567278_5 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 604.0
HKD1_k127_2567278_6 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 544.0
HKD1_k127_2567278_7 Helix-turn-helix domain, rpiR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 525.0
HKD1_k127_2567278_8 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008663 522.0
HKD1_k127_2567278_9 Belongs to the MIP aquaporin (TC 1.A.8) family K02440,K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 486.0
HKD1_k127_2980321_0 Initiator Replication protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 544.0
HKD1_k127_2980321_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 499.0
HKD1_k127_2980321_11 - - - - 0.000000000000855 72.0
HKD1_k127_2980321_12 - - - - 0.000000000008715 65.0
HKD1_k127_2980321_14 sequence-specific DNA binding - - - 0.0000003583 51.0
HKD1_k127_2980321_15 - - - - 0.0000006133 61.0
HKD1_k127_2980321_16 Bacterial extracellular solute-binding protein K02027 - - 0.0004241 52.0
HKD1_k127_2980321_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 438.0
HKD1_k127_2980321_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 414.0
HKD1_k127_2980321_4 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 366.0
HKD1_k127_2980321_5 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000001744 196.0
HKD1_k127_2980321_6 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000003136 189.0
HKD1_k127_2980321_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000005034 164.0
HKD1_k127_2980321_8 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000002978 153.0
HKD1_k127_2980321_9 toxin-antitoxin pair type II binding - - - 0.00000000000000000000000000000000000009694 143.0
HKD1_k127_3023698_0 Cache domain K03406 - - 0.0 1027.0
HKD1_k127_3023698_1 Phage plasmid primase P4 family - - - 2.075e-309 969.0
HKD1_k127_3023698_10 - - - - 0.0000000000000000000000000000000000000000000000000000001799 195.0
HKD1_k127_3023698_11 - - - - 0.0000000000000000000000000000000000000000000000006961 176.0
HKD1_k127_3023698_12 Staphylococcal protein of unknown function (DUF960) - - - 0.00000000000000000000000000000000000008543 143.0
HKD1_k127_3023698_15 - - - - 0.0000000000000000000000000003048 130.0
HKD1_k127_3023698_17 Phage envelope protein - - - 0.00000000000002253 74.0
HKD1_k127_3023698_18 - - - - 0.0000000008822 64.0
HKD1_k127_3023698_19 Protein of unknown function (DUF1398) - - - 0.000000001291 61.0
HKD1_k127_3023698_2 Na+/H+ antiporter family K03315 - - 1.583e-258 802.0
HKD1_k127_3023698_20 - - - - 0.0000004024 52.0
HKD1_k127_3023698_21 PFAM SEC-C motif - - - 0.0009763 52.0
HKD1_k127_3023698_3 Aminotransferase class I and II K14155 - 4.4.1.8 6.517e-230 714.0
HKD1_k127_3023698_4 Psort location Cytoplasmic, score K06400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 539.0
HKD1_k127_3023698_5 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 507.0
HKD1_k127_3023698_6 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008132 270.0
HKD1_k127_3023698_7 NB-ARC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006927 270.0
HKD1_k127_3023698_9 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.00000000000000000000000000000000000000000000000000000000000001546 218.0
HKD1_k127_3054339_0 Lysine-2,3-aminomutase K19814 GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0016853,GO:0016866,GO:0016869,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051536,GO:0051540,GO:0070279,GO:0097159,GO:1901363 5.4.3.9 5.931e-260 803.0
HKD1_k127_3054339_1 Psort location Cytoplasmic, score K00266 - 1.4.1.13,1.4.1.14 1.941e-251 781.0
HKD1_k127_3054339_2 - - - - 1.437e-196 625.0
HKD1_k127_3054339_3 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 567.0
HKD1_k127_3054339_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 469.0
HKD1_k127_3054339_5 Phosphotransferase system, EIIC K02768,K02769,K02770 - 2.7.1.202 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 415.0
HKD1_k127_3054339_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 375.0
HKD1_k127_3054339_7 - - - - 0.0000000000000000000000000000000000000000000000002374 178.0
HKD1_k127_3054339_8 - - - - 0.0000000000000000000000000001082 116.0
HKD1_k127_3054339_9 Subtilase family - - - 0.000000000000000000008631 93.0
HKD1_k127_3054843_0 helicase involved in DNA repair and perhaps also replication K03722 - 3.6.4.12 0.0 1132.0
HKD1_k127_3054843_1 OPT oligopeptide transporter protein - - - 2.584e-318 984.0
HKD1_k127_3054843_10 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001373 284.0
HKD1_k127_3054843_11 ECF-type riboflavin transporter, S component - - - 0.00000000000000000000000000000000000000000000000000000000000000000003119 237.0
HKD1_k127_3054843_12 TrkA-C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000789 228.0
HKD1_k127_3054843_13 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000000000000000000000000000000000000002109 180.0
HKD1_k127_3054843_14 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000000000000000000000000000000004219 174.0
HKD1_k127_3054843_15 Transcriptional regulator K10947 - - 0.00000000000000000000000000000000000000001563 155.0
HKD1_k127_3054843_17 - - - - 0.000000000000000000000000000000004258 138.0
HKD1_k127_3054843_18 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000003973 95.0
HKD1_k127_3054843_19 permease K07089 - - 0.000006093 48.0
HKD1_k127_3054843_2 Polysaccharide biosynthesis C-terminal domain - - - 2.131e-262 812.0
HKD1_k127_3054843_3 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 532.0
HKD1_k127_3054843_4 Protein of unknown function (DUF1648) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 527.0
HKD1_k127_3054843_5 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 532.0
HKD1_k127_3054843_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 443.0
HKD1_k127_3054843_7 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 437.0
HKD1_k127_3054843_8 EcsC protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 399.0
HKD1_k127_3054843_9 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008644 342.0
HKD1_k127_339678_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K20447 - 1.17.1.5 0.0 1246.0
HKD1_k127_339678_1 Adenine deaminase C-terminal domain K01486 - 3.5.4.2 0.0 1114.0
HKD1_k127_339678_10 Amidohydrolase family K01487 - 3.5.4.3 1.64e-244 759.0
HKD1_k127_339678_11 permease K06901 - - 6.285e-243 754.0
HKD1_k127_339678_12 Permease family K03458,K16345 - - 2.407e-226 707.0
HKD1_k127_339678_13 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 1.302e-212 662.0
HKD1_k127_339678_14 Formiminotransferase domain, N-terminal subdomain K00603,K01746 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 575.0
HKD1_k127_339678_15 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 574.0
HKD1_k127_339678_16 glycine, betaine K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 574.0
HKD1_k127_339678_17 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 572.0
HKD1_k127_339678_18 Two component signalling adaptor domain K03407,K03415 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 544.0
HKD1_k127_339678_19 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 537.0
HKD1_k127_339678_2 Class II release factor RF3, C-terminal domain K02837 - - 0.0 1029.0
HKD1_k127_339678_20 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 529.0
HKD1_k127_339678_21 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 507.0
HKD1_k127_339678_22 DUF based on E. rectale Gene description (DUF3880) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 472.0
HKD1_k127_339678_23 Phage integrase, N-terminal SAM-like domain K14059 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 458.0
HKD1_k127_339678_24 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 442.0
HKD1_k127_339678_25 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 428.0
HKD1_k127_339678_26 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 409.0
HKD1_k127_339678_27 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 404.0
HKD1_k127_339678_28 RecT family K07455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 404.0
HKD1_k127_339678_29 Belongs to the UPF0761 family K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 397.0
HKD1_k127_339678_3 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835,K01840 - 5.4.2.2,5.4.2.8 0.0 1018.0
HKD1_k127_339678_30 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 396.0
HKD1_k127_339678_31 CO dehydrogenase flavoprotein C-terminal domain K20445 - 1.17.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 391.0
HKD1_k127_339678_32 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 387.0
HKD1_k127_339678_33 Domain of unknown function (DUF348) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 384.0
HKD1_k127_339678_34 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 406.0
HKD1_k127_339678_35 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 377.0
HKD1_k127_339678_36 Cobalamin synthesis protein cobW C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 374.0
HKD1_k127_339678_37 LUD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 368.0
HKD1_k127_339678_38 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 353.0
HKD1_k127_339678_39 Leucine Rich repeats (2 copies) K13730 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 348.0
HKD1_k127_339678_4 Amidohydrolase family K01464,K01465,K01466 - 3.5.2.2,3.5.2.3,3.5.2.5 0.0 997.0
HKD1_k127_339678_40 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 312.0
HKD1_k127_339678_41 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002234 307.0
HKD1_k127_339678_42 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004843 265.0
HKD1_k127_339678_43 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002042 254.0
HKD1_k127_339678_44 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005062 277.0
HKD1_k127_339678_45 PilZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001825 228.0
HKD1_k127_339678_46 ORF6N domain - - - 0.0000000000000000000000000000000000000000000000000000000001301 214.0
HKD1_k127_339678_47 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000002499 198.0
HKD1_k127_339678_49 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000008196 190.0
HKD1_k127_339678_5 Domain of unknown function (DUF4445) - - - 3.348e-294 912.0
HKD1_k127_339678_50 N-terminal phage replisome organiser (Phage_rep_org_N) - - - 0.00000000000000000000000000000000000000000000000001276 190.0
HKD1_k127_339678_51 BMC - - - 0.0000000000000000000000000000000000000000000000218 170.0
HKD1_k127_339678_52 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000002037 175.0
HKD1_k127_339678_53 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000003442 167.0
HKD1_k127_339678_54 BMC - - - 0.000000000000000000000000000000000000000000003917 166.0
HKD1_k127_339678_55 BMC - - - 0.00000000000000000000000000000000000005298 143.0
HKD1_k127_339678_56 nuclear chromosome segregation - - - 0.00000000000000000000000000000000001946 155.0
HKD1_k127_339678_57 peptidase - - - 0.00000000000000000000000000000000001988 158.0
HKD1_k127_339678_58 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000000000000000004788 118.0
HKD1_k127_339678_59 - - - - 0.0000000000000000000000000009205 117.0
HKD1_k127_339678_6 DbpA RNA binding domain K05592 - 3.6.4.13 1.162e-285 880.0
HKD1_k127_339678_60 Bacterial inner membrane protein - - - 0.00000000000000000000000006402 109.0
HKD1_k127_339678_61 Domain of unknown function (DUF4397) - - - 0.0000000000000000000003334 105.0
HKD1_k127_339678_63 DnaD domain protein - - - 0.000000000000000009072 93.0
HKD1_k127_339678_64 - - - - 0.0000000000000004696 86.0
HKD1_k127_339678_66 Glycosyltransferase like family 2 - - - 0.00000000001318 79.0
HKD1_k127_339678_67 PFAM Integrase catalytic region K07497 - - 0.00000003135 55.0
HKD1_k127_339678_68 Helix-turn-helix - - - 0.0000001331 55.0
HKD1_k127_339678_7 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 3.776e-267 825.0
HKD1_k127_339678_8 Aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 9.278e-261 807.0
HKD1_k127_339678_9 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 1.405e-250 780.0
HKD1_k127_347832_0 RQC K03654 - 3.6.4.12 0.0 1442.0
HKD1_k127_347832_1 diguanylate cyclase - - - 3.471e-271 846.0
HKD1_k127_347832_10 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 597.0
HKD1_k127_347832_11 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 594.0
HKD1_k127_347832_12 biosynthesis protein ThiH K03150 - 4.1.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 580.0
HKD1_k127_347832_13 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 574.0
HKD1_k127_347832_14 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 567.0
HKD1_k127_347832_15 COG COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 537.0
HKD1_k127_347832_16 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 523.0
HKD1_k127_347832_17 MATE efflux family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 526.0
HKD1_k127_347832_18 Catalyzes the sodium-dependent transport of glutamate K03312 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 505.0
HKD1_k127_347832_19 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 487.0
HKD1_k127_347832_2 import. Responsible for energy coupling to the transport system K10441,K10542 - 3.6.3.17 4.852e-267 827.0
HKD1_k127_347832_20 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 482.0
HKD1_k127_347832_21 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 482.0
HKD1_k127_347832_22 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 452.0
HKD1_k127_347832_23 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 451.0
HKD1_k127_347832_24 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 449.0
HKD1_k127_347832_25 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 449.0
HKD1_k127_347832_26 PFAM periplasmic binding protein K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 450.0
HKD1_k127_347832_27 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 444.0
HKD1_k127_347832_28 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 439.0
HKD1_k127_347832_29 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 434.0
HKD1_k127_347832_3 Na Pi-cotransporter II-like protein K03324 - - 3.521e-262 816.0
HKD1_k127_347832_30 Thiamine biosynthesis protein ThiF K03148 - 2.7.7.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 421.0
HKD1_k127_347832_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 421.0
HKD1_k127_347832_32 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 411.0
HKD1_k127_347832_33 FGGY family of carbohydrate kinases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 410.0
HKD1_k127_347832_34 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 326.0
HKD1_k127_347832_35 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 320.0
HKD1_k127_347832_36 3D domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 298.0
HKD1_k127_347832_37 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 282.0
HKD1_k127_347832_38 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 282.0
HKD1_k127_347832_39 molybdenum cofactor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 281.0
HKD1_k127_347832_4 Diguanylate cyclase - - - 1.057e-258 810.0
HKD1_k127_347832_40 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 286.0
HKD1_k127_347832_41 BioY family K03523 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003679 271.0
HKD1_k127_347832_42 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001059 267.0
HKD1_k127_347832_43 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009949 252.0
HKD1_k127_347832_44 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose K06726 - 5.4.99.62 0.00000000000000000000000000000000000000000000000000000000000000000003 233.0
HKD1_k127_347832_45 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000001162 230.0
HKD1_k127_347832_46 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000009535 227.0
HKD1_k127_347832_47 - - - - 0.00000000000000000000000000000000000000000000000000000000004952 206.0
HKD1_k127_347832_48 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000005104 211.0
HKD1_k127_347832_49 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000000000000003476 185.0
HKD1_k127_347832_5 Belongs to the 'phage' integrase family - - - 7.13e-247 780.0
HKD1_k127_347832_51 - - - - 0.00000000000000000000000000000000000000000000008727 169.0
HKD1_k127_347832_52 Protein of unknown function (DUF3892) - - - 0.00000000000000000000000000000000000000000174 157.0
HKD1_k127_347832_53 - - - - 0.00000000000000000000000000000000000000001417 154.0
HKD1_k127_347832_54 Protein of unknown function (DUF1284) K09706 - - 0.0000000000000000000000000000003074 126.0
HKD1_k127_347832_55 NUBPL iron-transfer P-loop NTPase - - - 0.0000000000000000000000000000005431 138.0
HKD1_k127_347832_57 - - - - 0.000000000000000000000004478 102.0
HKD1_k127_347832_58 chain length determinant protein - - - 0.00000000000000000000001324 115.0
HKD1_k127_347832_59 thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000000006473 88.0
HKD1_k127_347832_6 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 2.838e-227 707.0
HKD1_k127_347832_60 transcriptional regulator - - - 0.000000000000000001993 90.0
HKD1_k127_347832_61 Pectate lyase superfamily protein - - - 0.0000000002628 73.0
HKD1_k127_347832_62 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000001498 66.0
HKD1_k127_347832_63 ethanolamine kinase activity K00021,K07251 - 1.1.1.34,2.7.1.89 0.0000000368 65.0
HKD1_k127_347832_7 Belongs to the peptidase S11 family K07258 - 3.4.16.4 1.32e-221 691.0
HKD1_k127_347832_8 Sodium/hydrogen exchanger family - - - 7.262e-219 685.0
HKD1_k127_347832_9 helicase superfamily c-terminal domain K05592 - 3.6.4.13 5.527e-218 678.0
HKD1_k127_363461_0 Psort location Cytoplasmic, score K00656 - 2.3.1.54 0.0 1462.0
HKD1_k127_363461_1 CO dehydrogenase/acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.0 1356.0
HKD1_k127_363461_10 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 1.835e-283 872.0
HKD1_k127_363461_11 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 1.203e-275 850.0
HKD1_k127_363461_12 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.44e-245 762.0
HKD1_k127_363461_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 8.388e-234 725.0
HKD1_k127_363461_14 Aminotransferase class-V K04487 - 2.8.1.7 2.161e-222 692.0
HKD1_k127_363461_15 Stage V sporulation protein AD K06406 - - 4.384e-210 654.0
HKD1_k127_363461_16 TPR repeat - - - 6.58e-199 621.0
HKD1_k127_363461_17 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 1.182e-194 610.0
HKD1_k127_363461_18 L-asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 604.0
HKD1_k127_363461_19 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 589.0
HKD1_k127_363461_2 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1299.0
HKD1_k127_363461_20 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 574.0
HKD1_k127_363461_21 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 558.0
HKD1_k127_363461_22 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 548.0
HKD1_k127_363461_23 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 534.0
HKD1_k127_363461_24 Pterin binding enzyme K15023 - 2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 531.0
HKD1_k127_363461_25 Phosphate acetyl/butaryl transferase K00634 - 2.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 524.0
HKD1_k127_363461_26 Anion-transporting ATPase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 514.0
HKD1_k127_363461_27 SpoIVB peptidase S55 K06399 - 3.4.21.116 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 503.0
HKD1_k127_363461_28 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 499.0
HKD1_k127_363461_29 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 495.0
HKD1_k127_363461_3 DNA helicase K03657 - 3.6.4.12 0.0 1219.0
HKD1_k127_363461_30 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 483.0
HKD1_k127_363461_31 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 483.0
HKD1_k127_363461_32 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 475.0
HKD1_k127_363461_33 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 471.0
HKD1_k127_363461_34 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 456.0
HKD1_k127_363461_35 Zinc dependent phospholipase C (alpha toxin) K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 419.0
HKD1_k127_363461_36 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 413.0
HKD1_k127_363461_37 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 406.0
HKD1_k127_363461_38 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 387.0
HKD1_k127_363461_39 Sporulation protein YunB (Spo_YunB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 381.0
HKD1_k127_363461_4 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0 1184.0
HKD1_k127_363461_40 Formiminotransferase-cyclodeaminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 379.0
HKD1_k127_363461_41 Protein of unknown function (DUF1461) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 336.0
HKD1_k127_363461_43 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition K06379 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006442 264.0
HKD1_k127_363461_44 SpoVAC/SpoVAEB sporulation membrane protein K06405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008564 264.0
HKD1_k127_363461_45 Domain of unknown function (DUF3842) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000046 250.0
HKD1_k127_363461_46 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000007252 231.0
HKD1_k127_363461_47 Psort location CytoplasmicMembrane, score K06404 - - 0.000000000000000000000000000000000000000000000000000000000000000002225 228.0
HKD1_k127_363461_48 SpoVAC/SpoVAEB sporulation membrane protein K06407 - - 0.0000000000000000000000000000000000000000000000000000000000000008849 219.0
HKD1_k127_363461_49 STAS domain K06378 - - 0.00000000000000000000000000000000000000000000000000000000000009908 213.0
HKD1_k127_363461_5 Domain of unknown function (DUF4445) - - - 0.0 1182.0
HKD1_k127_363461_50 - - - - 0.00000000000000000000000000000000000000000000000000000886 190.0
HKD1_k127_363461_51 Cysteine-rich small domain K07162 - - 0.0000000000000000000000000000000000000000000000001316 177.0
HKD1_k127_363461_52 - - - - 0.000000000000000000000000000000000000001102 149.0
HKD1_k127_363461_53 Predicted RNA-binding protein - - - 0.000000000000000000000000000000002434 129.0
HKD1_k127_363461_54 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07502 - - 0.0004604 43.0
HKD1_k127_363461_6 Formyltetrahydrofolate synthetase K01938 - 6.3.4.3 0.0 1027.0
HKD1_k127_363461_7 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0 1003.0
HKD1_k127_363461_8 ABC transporter, ATP-binding protein K06158 - - 2.92e-321 985.0
HKD1_k127_363461_9 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 6.582e-318 983.0
HKD1_k127_3662056_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 4.645e-263 812.0
HKD1_k127_3662056_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 4.756e-247 764.0
HKD1_k127_3662056_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 531.0
HKD1_k127_3662056_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 383.0
HKD1_k127_3662056_4 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 321.0
HKD1_k127_3662056_5 Hydrolase, HD family K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 305.0
HKD1_k127_3662056_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000000000000000000000000162 230.0
HKD1_k127_3662056_7 Helix-turn-helix domain K07483 - - 0.0004217 42.0
HKD1_k127_3679388_0 Phage portal protein, SPP1 Gp6-like - - - 3.648e-251 782.0
HKD1_k127_3679388_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - 1.498e-208 650.0
HKD1_k127_3679388_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 304.0
HKD1_k127_3679388_11 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005961 249.0
HKD1_k127_3679388_12 Phage tail tube protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001314 222.0
HKD1_k127_3679388_13 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000002591 219.0
HKD1_k127_3679388_14 Phage XkdN-like tail assembly chaperone protein, TAC - - - 0.0000000000000000000000000000000000000000000000000000001567 197.0
HKD1_k127_3679388_15 Uncharacterised protein conserved in bacteria (DUF2313) - - - 0.0000000000000000000000000000000000000000000000000005633 190.0
HKD1_k127_3679388_16 Phage virion morphogenesis - - - 0.0000000000000000000000000000000000000000000001604 171.0
HKD1_k127_3679388_17 Protein of unknown function (DUF2634) - - - 0.0000000000000000000000000000000000000000000139 166.0
HKD1_k127_3679388_18 Endodeoxyribonuclease RusA - - - 0.0000000000000000000000000000000000000000000917 164.0
HKD1_k127_3679388_19 - - - - 0.000000000000000000000000000000000000000005868 157.0
HKD1_k127_3679388_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 596.0
HKD1_k127_3679388_20 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000007132 149.0
HKD1_k127_3679388_21 - - - - 0.000000000000000000000000000000000000001558 149.0
HKD1_k127_3679388_22 Uncharacterized conserved protein (DUF2190) - - - 0.00000000000000000000000000000000000003249 146.0
HKD1_k127_3679388_23 sigma factor activity - - - 0.0000000000000000000000000000007475 127.0
HKD1_k127_3679388_24 Phage terminase large subunit - - - 0.0000000000000000000007317 98.0
HKD1_k127_3679388_25 Single-stranded DNA-binding protein K03111 - - 0.00000000000000000004696 90.0
HKD1_k127_3679388_26 Phage tail tape measure protein TP901 - - - 0.0000000000000001098 96.0
HKD1_k127_3679388_27 - - - - 0.00000000000000336 77.0
HKD1_k127_3679388_28 - - - - 0.00000000000006359 76.0
HKD1_k127_3679388_29 Phage uncharacterised protein (Phage_XkdX) - - - 0.00000000007374 64.0
HKD1_k127_3679388_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 528.0
HKD1_k127_3679388_30 - - - - 0.00000000007374 64.0
HKD1_k127_3679388_32 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.0000006333 59.0
HKD1_k127_3679388_4 phage tail tape measure protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 545.0
HKD1_k127_3679388_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 456.0
HKD1_k127_3679388_6 Phage tail sheath protein beta-sandwich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 427.0
HKD1_k127_3679388_7 Baseplate J-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 352.0
HKD1_k127_3679388_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 346.0
HKD1_k127_3679388_9 DNA packaging - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 316.0
HKD1_k127_3891421_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03169 - 5.99.1.2 0.0 1315.0
HKD1_k127_3891421_1 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1189.0
HKD1_k127_3891421_10 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 529.0
HKD1_k127_3891421_11 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 459.0
HKD1_k127_3891421_12 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 424.0
HKD1_k127_3891421_13 flagellar basal body K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 404.0
HKD1_k127_3891421_14 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 401.0
HKD1_k127_3891421_15 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 396.0
HKD1_k127_3891421_16 Sigma-70 region 3 K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 374.0
HKD1_k127_3891421_17 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 337.0
HKD1_k127_3891421_18 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 322.0
HKD1_k127_3891421_19 Hexapeptide repeat of succinyl-transferase K02617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007656 263.0
HKD1_k127_3891421_2 Bacterial export proteins, family 1 K02401,K13820 - - 1.454e-318 983.0
HKD1_k127_3891421_20 Domain of unknown function (DUF2935) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002387 237.0
HKD1_k127_3891421_21 Putative Fe-S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000006376 226.0
HKD1_k127_3891421_22 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000000000000000000001129 211.0
HKD1_k127_3891421_23 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000002326 204.0
HKD1_k127_3891421_24 Thiamine transporter protein (Thia_YuaJ) K16789 - - 0.00000000000000000000000000000000000000000000000000000004097 201.0
HKD1_k127_3891421_25 - - - - 0.000000000000000000000000000000000000000000000002634 175.0
HKD1_k127_3891421_27 Uncharacterized protein conserved in bacteria (DUF2325) - - - 0.000000000000000000000000000000000000000000001417 166.0
HKD1_k127_3891421_28 Bacterial export proteins, family 3 K02420 - - 0.00000000000000000000000000000000000000006891 152.0
HKD1_k127_3891421_29 flagellar motor switch protein K02417 - - 0.0000000000000000000000000000000000000003435 149.0
HKD1_k127_3891421_3 PAS fold - - - 6.444e-318 992.0
HKD1_k127_3891421_30 Domain of unknown function (DUF4397) - - - 0.000000000000000000002068 102.0
HKD1_k127_3891421_4 Amino acid permease - - - 9.1e-282 870.0
HKD1_k127_3891421_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 8.091e-274 844.0
HKD1_k127_3891421_6 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 1.506e-243 754.0
HKD1_k127_3891421_7 Beta-eliminating lyase - - - 1.072e-212 668.0
HKD1_k127_3891421_8 Beta-eliminating lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 583.0
HKD1_k127_3891421_9 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 558.0
HKD1_k127_392460_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1612.0
HKD1_k127_392460_1 DNA topoisomerase K03169 - 5.99.1.2 0.0 1353.0
HKD1_k127_392460_10 Glycine/sarcosine/betaine reductase component B subunits K10671 - 1.21.4.2 1.892e-275 850.0
HKD1_k127_392460_100 flagellar protein FliS K02422 - - 0.000000000000000000000000000000000000000000000000000000001129 202.0
HKD1_k127_392460_101 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00000000000000000000000000000000000000000000000000000004821 198.0
HKD1_k127_392460_102 Double zinc ribbon - - - 0.000000000000000000000000000000000000000000000003432 173.0
HKD1_k127_392460_103 Domain of Unknown Function (DUF1540) - - - 0.00000000000000000000000000000000000000000000006188 170.0
HKD1_k127_392460_104 CotJB protein K06333 - - 0.0000000000000000000000000000000000000000000006412 166.0
HKD1_k127_392460_105 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000000000000000000000000000000006629 168.0
HKD1_k127_392460_106 selenoprotein B, glycine betaine sarcosine D-proline reductase K10672 - 1.21.4.2 0.000000000000000000000000000000000000000000006634 164.0
HKD1_k127_392460_107 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000000000000000000002877 151.0
HKD1_k127_392460_108 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000002582 158.0
HKD1_k127_392460_109 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000002582 147.0
HKD1_k127_392460_11 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 1.199e-261 808.0
HKD1_k127_392460_110 YabP family - - - 0.00000000000000000000000000000000000004049 143.0
HKD1_k127_392460_111 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.00000000000000000000000000000000000009498 144.0
HKD1_k127_392460_112 Domain of Unknown Function (DUF1540) - - - 0.000000000000000000000000000000001146 133.0
HKD1_k127_392460_113 Domain of unknown function (DUF3794) - - - 0.000000000000000000000000000000001629 142.0
HKD1_k127_392460_114 Anti-sigma-28 factor, FlgM K02398 - - 0.000000000000000000000000000000262 124.0
HKD1_k127_392460_115 - - - - 0.0000000000000000000000000000008052 123.0
HKD1_k127_392460_116 Spore coat associated protein JA (CotJA) - - - 0.000000000000000000000000000003805 119.0
HKD1_k127_392460_117 4Fe-4S dicluster domain - - - 0.000000000000000000000000000005353 118.0
HKD1_k127_392460_118 Bacterial flagellin C-terminal helical region K02406 - - 0.00000000000000000000000002592 108.0
HKD1_k127_392460_119 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000005252 109.0
HKD1_k127_392460_12 Acts as a magnesium transporter K06213 - - 8.738e-259 801.0
HKD1_k127_392460_120 - - - - 0.000000000000000000002959 105.0
HKD1_k127_392460_121 glycine sarcosine betaine reductase complex protein A K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.000000000000000000003031 93.0
HKD1_k127_392460_122 - - - - 0.000000000000000006397 93.0
HKD1_k127_392460_123 - - - - 0.000000000005627 69.0
HKD1_k127_392460_124 - - - - 0.00000001359 60.0
HKD1_k127_392460_126 - - - - 0.0000001764 57.0
HKD1_k127_392460_128 - - - - 0.000003059 53.0
HKD1_k127_392460_13 Aminotransferase class I and II K00832 - 2.6.1.57 1.032e-255 790.0
HKD1_k127_392460_131 - - - - 0.0003634 47.0
HKD1_k127_392460_14 FtsX-like permease family K02004 - - 1.19e-234 743.0
HKD1_k127_392460_15 PFAM fatty acid synthesis plsX protein K21576 - 1.21.4.2,1.21.4.3,1.21.4.4 5.339e-223 694.0
HKD1_k127_392460_16 Sodium:dicarboxylate symporter family - - - 3.175e-222 694.0
HKD1_k127_392460_17 Putative stage IV sporulation protein YqfD K06438 - - 4.551e-222 694.0
HKD1_k127_392460_18 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672 - 1.21.4.2 3.338e-213 664.0
HKD1_k127_392460_19 Belongs to the acetokinase family K00929 - 2.7.2.7 6.111e-208 649.0
HKD1_k127_392460_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1246.0
HKD1_k127_392460_20 Sterol carrier protein domain - - - 6.079e-205 642.0
HKD1_k127_392460_21 Protein tyrosine kinase - - - 1.22e-204 639.0
HKD1_k127_392460_22 Competence protein K02238 - - 1.591e-201 634.0
HKD1_k127_392460_23 Involved in the biosynthesis of porphyrin-containing compound - - - 3.908e-201 631.0
HKD1_k127_392460_24 Putative diguanylate phosphodiesterase - - - 3.323e-199 628.0
HKD1_k127_392460_25 Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - 1.685e-197 621.0
HKD1_k127_392460_26 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 3.86e-196 612.0
HKD1_k127_392460_27 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 604.0
HKD1_k127_392460_28 Glycyl-tRNA synthetase alpha K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 596.0
HKD1_k127_392460_29 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 596.0
HKD1_k127_392460_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0 1172.0
HKD1_k127_392460_30 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 594.0
HKD1_k127_392460_31 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 588.0
HKD1_k127_392460_32 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 590.0
HKD1_k127_392460_33 Exonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 584.0
HKD1_k127_392460_34 Initiates the rapid degradation of small, acid-soluble proteins during spore germination K06012 - 3.4.24.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 581.0
HKD1_k127_392460_35 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 574.0
HKD1_k127_392460_36 Protein of unknown function DUF115 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 586.0
HKD1_k127_392460_37 biosynthesis protein K15894 - 4.2.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 560.0
HKD1_k127_392460_38 Flagellar hook-associated protein 2 N-terminus K02407 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 559.0
HKD1_k127_392460_39 Belongs to the TtcA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 546.0
HKD1_k127_392460_4 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1165.0
HKD1_k127_392460_40 Subtilase family K01342,K13275 - 3.4.21.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 549.0
HKD1_k127_392460_41 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 541.0
HKD1_k127_392460_42 PFAM NLP P60 protein K11060,K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 540.0
HKD1_k127_392460_43 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 520.0
HKD1_k127_392460_44 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 523.0
HKD1_k127_392460_45 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 506.0
HKD1_k127_392460_46 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 511.0
HKD1_k127_392460_47 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 504.0
HKD1_k127_392460_48 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 509.0
HKD1_k127_392460_49 synthase K01654,K15898 - 2.5.1.56,2.5.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 501.0
HKD1_k127_392460_5 Heat shock 70 kDa protein K04043 - - 0.0 1119.0
HKD1_k127_392460_50 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 469.0
HKD1_k127_392460_51 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 461.0
HKD1_k127_392460_52 ThiF family K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 444.0
HKD1_k127_392460_53 FtsX-like permease family K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 447.0
HKD1_k127_392460_54 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 443.0
HKD1_k127_392460_55 Domain of unknown function (DUF348) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 440.0
HKD1_k127_392460_56 stage II sporulation protein P K06385 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 439.0
HKD1_k127_392460_57 Bacterial flagellin N-terminal helical region K02397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 437.0
HKD1_k127_392460_58 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 423.0
HKD1_k127_392460_59 Transglycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 415.0
HKD1_k127_392460_6 Propionate catabolism activator K02688 - - 0.0 1054.0
HKD1_k127_392460_60 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 400.0
HKD1_k127_392460_61 Prokaryotic diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 400.0
HKD1_k127_392460_62 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 397.0
HKD1_k127_392460_63 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 392.0
HKD1_k127_392460_64 Manganese containing catalase K06334 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 371.0
HKD1_k127_392460_65 DeoR-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 370.0
HKD1_k127_392460_66 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 368.0
HKD1_k127_392460_67 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 359.0
HKD1_k127_392460_68 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 346.0
HKD1_k127_392460_69 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 340.0
HKD1_k127_392460_7 OPT oligopeptide transporter protein - - - 0.0 1030.0
HKD1_k127_392460_70 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 334.0
HKD1_k127_392460_71 Cytidylyltransferase K07257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 340.0
HKD1_k127_392460_72 3'-5' exonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 320.0
HKD1_k127_392460_73 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 322.0
HKD1_k127_392460_74 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 347.0
HKD1_k127_392460_75 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 323.0
HKD1_k127_392460_76 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 296.0
HKD1_k127_392460_77 overlaps another CDS with the same product name K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 295.0
HKD1_k127_392460_78 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 291.0
HKD1_k127_392460_79 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 285.0
HKD1_k127_392460_8 Oligoendopeptidase, M3 family - - - 0.0 1007.0
HKD1_k127_392460_80 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009154 278.0
HKD1_k127_392460_81 pseudaminic acid biosynthesis-associated protein PseG K15897 - 3.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000004107 270.0
HKD1_k127_392460_82 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000421 257.0
HKD1_k127_392460_83 TspO/MBR family K05770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001329 258.0
HKD1_k127_392460_84 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000001364 252.0
HKD1_k127_392460_85 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001962 258.0
HKD1_k127_392460_86 Protein of unknown function (DUF3785) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001023 237.0
HKD1_k127_392460_87 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000000000000000001265 238.0
HKD1_k127_392460_88 Protein of unknown function (DUF327) K09770 - - 0.00000000000000000000000000000000000000000000000000000000000000000009798 232.0
HKD1_k127_392460_89 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000017 230.0
HKD1_k127_392460_9 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K21577 - 1.21.4.2,1.21.4.3,1.21.4.4 3.823e-316 970.0
HKD1_k127_392460_90 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000006911 234.0
HKD1_k127_392460_91 Hit family K02503 - - 0.000000000000000000000000000000000000000000000000000000000000000586 220.0
HKD1_k127_392460_92 Chromate transport protein K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000009032 223.0
HKD1_k127_392460_93 - - - - 0.00000000000000000000000000000000000000000000000000000000000002956 216.0
HKD1_k127_392460_94 - - - - 0.00000000000000000000000000000000000000000000000000000000000004188 218.0
HKD1_k127_392460_95 Domain of unknown function (DUF4342) - - - 0.00000000000000000000000000000000000000000000000000000000000005021 219.0
HKD1_k127_392460_96 - - - - 0.000000000000000000000000000000000000000000000000000000000003472 214.0
HKD1_k127_392460_97 FlgN protein - - - 0.00000000000000000000000000000000000000000000000000000000001715 208.0
HKD1_k127_392460_98 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000000126 203.0
HKD1_k127_392460_99 Glycine reductase complex selenoprotein A K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0000000000000000000000000000000000000000000000000000000001857 203.0
HKD1_k127_4022201_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1507.0
HKD1_k127_4022201_1 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 2.789e-269 831.0
HKD1_k127_4022201_10 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 335.0
HKD1_k127_4022201_11 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 330.0
HKD1_k127_4022201_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 329.0
HKD1_k127_4022201_13 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 314.0
HKD1_k127_4022201_14 Part of a membrane complex involved in electron transport K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 284.0
HKD1_k127_4022201_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000271 282.0
HKD1_k127_4022201_16 ABC transporter K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000305 250.0
HKD1_k127_4022201_17 Transglycosylase SLT domain protein K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004052 250.0
HKD1_k127_4022201_18 Heavy-metal-associated domain - - - 0.00000000000000000000000000003328 118.0
HKD1_k127_4022201_19 - - - - 0.0000000000000000000000005058 106.0
HKD1_k127_4022201_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.136e-250 783.0
HKD1_k127_4022201_21 Recombinase zinc beta ribbon domain - - - 0.0008326 44.0
HKD1_k127_4022201_3 Cell shape determining protein, MreB Mrl family K03569 - - 1.16e-215 671.0
HKD1_k127_4022201_4 Electron transport complex K03616 - - 1.056e-196 614.0
HKD1_k127_4022201_5 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 599.0
HKD1_k127_4022201_6 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 418.0
HKD1_k127_4022201_7 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 404.0
HKD1_k127_4022201_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 372.0
HKD1_k127_4022201_9 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 350.0
HKD1_k127_4062274_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 7.366e-259 805.0
HKD1_k127_4062274_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 2.161e-222 692.0
HKD1_k127_4062274_10 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 442.0
HKD1_k127_4062274_11 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 436.0
HKD1_k127_4062274_12 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 410.0
HKD1_k127_4062274_13 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 391.0
HKD1_k127_4062274_14 NUBPL iron-transfer P-loop NTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 368.0
HKD1_k127_4062274_15 biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 353.0
HKD1_k127_4062274_16 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 350.0
HKD1_k127_4062274_17 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 360.0
HKD1_k127_4062274_18 Conserved phage C-terminus (Phg_2220_C) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 302.0
HKD1_k127_4062274_19 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 303.0
HKD1_k127_4062274_2 DnaB-like helicase N terminal domain - - - 1.422e-213 670.0
HKD1_k127_4062274_20 -O-antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000001609 243.0
HKD1_k127_4062274_21 VanZ like family - - - 0.000000000000000000000000000000000000000000000000000000000000001077 223.0
HKD1_k127_4062274_22 Glycosyl transferase family 2 K12990 - - 0.000000000000000000000000000000000000000000000000000000009647 203.0
HKD1_k127_4062274_23 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000009851 202.0
HKD1_k127_4062274_24 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000002337 181.0
HKD1_k127_4062274_25 - - - - 0.00000000000000000000000000000000000000003019 162.0
HKD1_k127_4062274_26 Mor transcription activator family - - - 0.00000000000000000000000000000000000385 138.0
HKD1_k127_4062274_27 DnaB-like helicase N terminal domain - - - 0.00000000000000000000000000000000005692 135.0
HKD1_k127_4062274_28 - - - - 0.0000000000000000000000000000000323 130.0
HKD1_k127_4062274_29 UDP-glucose 4-epimerase activity K01784 - 5.1.3.2 0.000000000000000000000000006934 110.0
HKD1_k127_4062274_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 6.27e-207 646.0
HKD1_k127_4062274_30 MacB-like periplasmic core domain K02004 - - 0.0000000000000000009066 99.0
HKD1_k127_4062274_31 Glycosyl transferase family 2 - - - 0.00000000000000006341 92.0
HKD1_k127_4062274_32 - - - - 0.00000000000001166 83.0
HKD1_k127_4062274_33 HlyD family secretion protein K02005 - - 0.0000003906 61.0
HKD1_k127_4062274_4 Male sterility protein K01710 - 4.2.1.46 7.049e-194 607.0
HKD1_k127_4062274_5 Domain of unknown function (DUF1972) K12996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 580.0
HKD1_k127_4062274_6 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 538.0
HKD1_k127_4062274_7 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 530.0
HKD1_k127_4062274_8 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 505.0
HKD1_k127_4062274_9 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 499.0
HKD1_k127_4082291_0 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.0 2288.0
HKD1_k127_4082291_1 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation K16899 - 3.6.4.12 0.0 2156.0
HKD1_k127_4082291_10 ABC transporter K06147 - - 1.245e-228 713.0
HKD1_k127_4082291_11 Transporter associated domain K03699 - - 7.038e-221 689.0
HKD1_k127_4082291_12 DNA helicase - - - 1.353e-206 661.0
HKD1_k127_4082291_13 helix_turn _helix lactose operon repressor K02529 - - 4.912e-200 625.0
HKD1_k127_4082291_14 37-kD nucleoid-associated bacterial protein - - - 2.236e-198 620.0
HKD1_k127_4082291_15 Polysaccharide biosynthesis protein K06409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 611.0
HKD1_k127_4082291_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 587.0
HKD1_k127_4082291_17 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 576.0
HKD1_k127_4082291_18 Formiminotransferase domain, N-terminal subdomain K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 565.0
HKD1_k127_4082291_19 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 537.0
HKD1_k127_4082291_2 Exonuclease SbcCD, C subunit K03546 - - 0.0 1619.0
HKD1_k127_4082291_20 Responsible for synthesis of pseudouridine from uracil K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 527.0
HKD1_k127_4082291_21 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 525.0
HKD1_k127_4082291_22 Psort location Cytoplasmic, score 8.87 K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 498.0
HKD1_k127_4082291_23 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 476.0
HKD1_k127_4082291_24 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 470.0
HKD1_k127_4082291_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 434.0
HKD1_k127_4082291_26 reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 407.0
HKD1_k127_4082291_27 Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 359.0
HKD1_k127_4082291_28 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009101 356.0
HKD1_k127_4082291_29 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 360.0
HKD1_k127_4082291_3 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0 1317.0
HKD1_k127_4082291_30 Phosphotransferase system, EIIC K07035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 353.0
HKD1_k127_4082291_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 340.0
HKD1_k127_4082291_32 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 298.0
HKD1_k127_4082291_33 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000002643 243.0
HKD1_k127_4082291_34 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006356 230.0
HKD1_k127_4082291_35 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000001015 195.0
HKD1_k127_4082291_36 - - - - 0.000000000000000000000000000000000000000000000000005492 184.0
HKD1_k127_4082291_37 - - - - 0.0000000000000000000000000000000000000000000000003447 180.0
HKD1_k127_4082291_38 response to hydrogen peroxide - - - 0.00000000000000000000000000000000000000000003051 167.0
HKD1_k127_4082291_39 - - - - 0.00000000000000000000000000000000000000000007298 159.0
HKD1_k127_4082291_4 DNA helicase K03657 - 3.6.4.12 0.0 1312.0
HKD1_k127_4082291_40 Protein of unknown function (DUF2500) - - - 0.0000000000000000000000000000000000000003903 152.0
HKD1_k127_4082291_41 - - - - 0.000000000000000000000000000000000000005223 145.0
HKD1_k127_4082291_42 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000001395 124.0
HKD1_k127_4082291_43 - - - - 0.0000000000000000000000000000001736 124.0
HKD1_k127_4082291_44 - - - - 0.000000000000000000000000000002117 122.0
HKD1_k127_4082291_45 - - - - 0.00000000000000000000000000001035 118.0
HKD1_k127_4082291_46 UPF0291 protein - - - 0.0000000000000000000000000005952 113.0
HKD1_k127_4082291_47 - - - - 0.000000000000000000000003018 102.0
HKD1_k127_4082291_5 Histidine ammonia-lyase K01745 - 4.3.1.3 2.43e-299 922.0
HKD1_k127_4082291_50 - - - - 0.0001025 46.0
HKD1_k127_4082291_6 M18 family aminopeptidase - - - 5.112e-286 880.0
HKD1_k127_4082291_7 Alanine-glyoxylate amino-transferase - - - 2.143e-266 826.0
HKD1_k127_4082291_8 Amidohydrolase family K01468 - 3.5.2.7 1.92e-248 769.0
HKD1_k127_4082291_9 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 2.144e-236 734.0
HKD1_k127_411298_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1117.0
HKD1_k127_411298_1 PFAM Cys Met metabolism K01760 - 4.4.1.8 2.249e-209 656.0
HKD1_k127_411298_11 ABC transporter K10010 - - 0.00000000000000000004239 90.0
HKD1_k127_411298_12 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 - 4.4.1.21 0.00000000001025 65.0
HKD1_k127_411298_13 ABC transporter K10010 - - 0.000703 42.0
HKD1_k127_411298_2 Belongs to the UPF0597 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 612.0
HKD1_k127_411298_3 cell wall binding repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 434.0
HKD1_k127_411298_4 ABC transporter K10010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 420.0
HKD1_k127_411298_5 NlpC/P60 family K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 423.0
HKD1_k127_411298_6 acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine K10009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 362.0
HKD1_k127_411298_7 Belongs to the bacterial solute-binding protein 3 family K02030,K02424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 291.0
HKD1_k127_411298_8 Ferredoxin - - - 0.00000000000000000000000000000000000000006413 154.0
HKD1_k127_411298_9 - - - - 0.0000000000000000000000000000000000009297 146.0
HKD1_k127_4164387_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 1.358e-300 925.0
HKD1_k127_4164387_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 5.865e-293 902.0
HKD1_k127_4164387_10 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 544.0
HKD1_k127_4164387_11 GHMP kinases N terminal domain K16651 - 2.7.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 490.0
HKD1_k127_4164387_12 sirohydrochlorin cobaltochelatase K02190 - 4.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 488.0
HKD1_k127_4164387_13 precorrin-3B C17-methyltransferase K05934,K21479 - 2.1.1.131,2.1.1.272 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 462.0
HKD1_k127_4164387_14 Precorrin-2 C(20)-methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 446.0
HKD1_k127_4164387_15 reductase K05895 - 1.3.1.106,1.3.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 420.0
HKD1_k127_4164387_16 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 401.0
HKD1_k127_4164387_17 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 385.0
HKD1_k127_4164387_18 Precorrin-6y C5,15-methyltransferase (Decarboxylating) K00595,K03399 - 2.1.1.132,2.1.1.289 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 362.0
HKD1_k127_4164387_19 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 361.0
HKD1_k127_4164387_2 Aminotransferase class-III K01845 - 5.4.3.8 6.327e-273 841.0
HKD1_k127_4164387_20 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 360.0
HKD1_k127_4164387_21 Tetrapyrrole (Corrin/Porphyrin) Methylases K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 354.0
HKD1_k127_4164387_22 Putative methyltransferase K00595,K02191 - 2.1.1.132,2.1.1.196 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 342.0
HKD1_k127_4164387_23 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 327.0
HKD1_k127_4164387_24 Putative NAD(P)-binding K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 315.0
HKD1_k127_4164387_26 - - - - 0.000000001428 59.0
HKD1_k127_4164387_28 - - - - 0.00000839 48.0
HKD1_k127_4164387_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 5.341e-268 829.0
HKD1_k127_4164387_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 5.579e-225 702.0
HKD1_k127_4164387_5 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 4.904e-223 694.0
HKD1_k127_4164387_6 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 7.974e-203 634.0
HKD1_k127_4164387_7 Belongs to the ALAD family K01698 - 4.2.1.24 3.065e-198 619.0
HKD1_k127_4164387_8 Aminotransferase class I and II K04720 - 4.1.1.81 9.399e-195 610.0
HKD1_k127_4164387_9 Cobalamin synthesis G C-terminus K02189 - 3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 549.0
HKD1_k127_4173404_0 Polysaccharide biosynthesis C-terminal domain - - - 3.816e-232 725.0
HKD1_k127_4173404_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 1.379e-195 614.0
HKD1_k127_4173404_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000001068 215.0
HKD1_k127_4173404_11 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.000000000000000000000000000000000000000000000000000000005739 200.0
HKD1_k127_4173404_12 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000005247 208.0
HKD1_k127_4173404_13 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000003684 193.0
HKD1_k127_4173404_14 - - - - 0.00000000000000000000000000000000000000000001275 180.0
HKD1_k127_4173404_15 Mor transcription activator family - - - 0.000000000000000000627 87.0
HKD1_k127_4173404_16 - - - - 0.000000000000003885 76.0
HKD1_k127_4173404_17 GHKL domain - - - 0.00000000004998 64.0
HKD1_k127_4173404_19 Subtilase family - - - 0.000005069 52.0
HKD1_k127_4173404_2 Efflux ABC transporter, permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 615.0
HKD1_k127_4173404_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 551.0
HKD1_k127_4173404_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 360.0
HKD1_k127_4173404_5 COG NOG17660 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 351.0
HKD1_k127_4173404_6 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 291.0
HKD1_k127_4173404_7 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 286.0
HKD1_k127_4173404_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001653 267.0
HKD1_k127_4173404_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001004 228.0
HKD1_k127_4225577_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.0 1077.0
HKD1_k127_4225577_1 ATPases associated with a variety of cellular activities K06158 - - 0.0 1064.0
HKD1_k127_4225577_10 Sodium:alanine symporter family K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 609.0
HKD1_k127_4225577_11 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 602.0
HKD1_k127_4225577_12 4Fe-4S dicluster domain K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 586.0
HKD1_k127_4225577_13 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 591.0
HKD1_k127_4225577_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 519.0
HKD1_k127_4225577_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 500.0
HKD1_k127_4225577_16 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009394 504.0
HKD1_k127_4225577_17 Oxidoreductase NAD-binding domain K16951 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 493.0
HKD1_k127_4225577_18 amidohydrolase K21613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 486.0
HKD1_k127_4225577_19 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 475.0
HKD1_k127_4225577_2 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 1.44e-321 987.0
HKD1_k127_4225577_20 PFAM GCN5-related N-acetyltransferase K06976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 460.0
HKD1_k127_4225577_21 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 449.0
HKD1_k127_4225577_22 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 429.0
HKD1_k127_4225577_23 Pterin binding enzyme K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 427.0
HKD1_k127_4225577_24 Formate/nitrite transporter K02598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 410.0
HKD1_k127_4225577_25 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 408.0
HKD1_k127_4225577_26 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 383.0
HKD1_k127_4225577_27 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 387.0
HKD1_k127_4225577_28 Bacterial dnaA protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 376.0
HKD1_k127_4225577_29 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 359.0
HKD1_k127_4225577_3 Na+/H+ antiporter family K03315 - - 1.253e-262 814.0
HKD1_k127_4225577_30 PFAM HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 360.0
HKD1_k127_4225577_31 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 316.0
HKD1_k127_4225577_32 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 304.0
HKD1_k127_4225577_33 Psort location CytoplasmicMembrane, score K16923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 294.0
HKD1_k127_4225577_34 Helix-turn-helix domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 291.0
HKD1_k127_4225577_35 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001941 280.0
HKD1_k127_4225577_36 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001377 275.0
HKD1_k127_4225577_37 4Fe-4S binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001383 278.0
HKD1_k127_4225577_38 helicase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002305 262.0
HKD1_k127_4225577_39 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003363 248.0
HKD1_k127_4225577_4 lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 1.517e-254 786.0
HKD1_k127_4225577_40 Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000000000000000000000000000000000000000000000001471 237.0
HKD1_k127_4225577_41 YqaJ viral recombinase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003432 235.0
HKD1_k127_4225577_42 GNAT family K03825 - - 0.0000000000000000000000000000000000000000000000000000000000000000004052 233.0
HKD1_k127_4225577_43 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000000000000000000000002377 230.0
HKD1_k127_4225577_44 alcohol dehydrogenase K18012 - 1.4.1.11 0.000000000000000000000000000000000000000000000000000000000000001273 219.0
HKD1_k127_4225577_45 Protein of unknown function (DUF3796) - - - 0.000000000000000000000000000000000000000000000000000000000000001401 219.0
HKD1_k127_4225577_46 Replication initiation and membrane attachment - - - 0.000000000000000000000000000000000000000000002291 179.0
HKD1_k127_4225577_47 domain, Protein - - - 0.0000000000000000000000000000000000000006477 166.0
HKD1_k127_4225577_48 PucR C-terminal helix-turn-helix domain - - - 0.000000000000000000000000000000000000003589 160.0
HKD1_k127_4225577_49 Domain of unknown function (DUF4177) - - - 0.00000000000000000000000000000000000002303 143.0
HKD1_k127_4225577_5 MFS/sugar transport protein K03292 - - 9.749e-200 631.0
HKD1_k127_4225577_50 PucR C-terminal helix-turn-helix domain - - - 0.00000000000000000000000000000006008 128.0
HKD1_k127_4225577_51 Protein of unknown function (DUF2922) - - - 0.00000000000000000000000000000029 123.0
HKD1_k127_4225577_52 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000000000000003682 123.0
HKD1_k127_4225577_53 Protein of unknown function (DUF2922) - - - 0.0000000000000000000000000000007501 122.0
HKD1_k127_4225577_54 - - - - 0.0000000000000000000000000003659 114.0
HKD1_k127_4225577_55 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000000000000000001068 113.0
HKD1_k127_4225577_56 Protein of unknown function (DUF1659) - - - 0.000000000000000000000000009823 110.0
HKD1_k127_4225577_57 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000006194 97.0
HKD1_k127_4225577_59 IrrE N-terminal-like domain - - - 0.00000000000000000006941 95.0
HKD1_k127_4225577_6 ATPase domain of DNA mismatch repair MUTS family K07456 - - 1.032e-199 633.0
HKD1_k127_4225577_60 methyltransferase - - - 0.0000000000000000001148 92.0
HKD1_k127_4225577_61 PFAM small acid-soluble spore protein alpha - - - 0.0000000000000000001908 89.0
HKD1_k127_4225577_62 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.00000000000003656 73.0
HKD1_k127_4225577_63 Beta/gamma crystallins - - - 0.000000000003315 79.0
HKD1_k127_4225577_64 AAA domain (dynein-related subfamily) K07452 - - 0.000000000004838 70.0
HKD1_k127_4225577_65 YvrJ protein family - - - 0.000000002985 57.0
HKD1_k127_4225577_66 YvrJ protein family - - - 0.00000003652 55.0
HKD1_k127_4225577_67 Mor transcription activator - - - 0.0000001626 53.0
HKD1_k127_4225577_68 ubiE/COQ5 methyltransferase family - - - 0.0000004037 55.0
HKD1_k127_4225577_69 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000007225 49.0
HKD1_k127_4225577_7 Glucose sorbosone - - - 4.143e-198 621.0
HKD1_k127_4225577_8 Calcineurin-like phosphoesterase - - - 4.878e-196 621.0
HKD1_k127_4225577_9 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00385 - - 1.885e-195 611.0
HKD1_k127_4333529_0 Pyruvate phosphate dikinase, PEP pyruvate binding domain - - - 0.0 1228.0
HKD1_k127_4333529_1 Psort location Cytoplasmic, score K01262 - 3.4.11.9 0.0 1018.0
HKD1_k127_4333529_10 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 590.0
HKD1_k127_4333529_11 calcium proton exchanger K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 580.0
HKD1_k127_4333529_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 553.0
HKD1_k127_4333529_13 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 491.0
HKD1_k127_4333529_14 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 478.0
HKD1_k127_4333529_15 alcohol dehydrogenase K18120 - 1.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 465.0
HKD1_k127_4333529_16 ABC transporter permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 426.0
HKD1_k127_4333529_17 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 396.0
HKD1_k127_4333529_18 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 402.0
HKD1_k127_4333529_19 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 380.0
HKD1_k127_4333529_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.757e-288 890.0
HKD1_k127_4333529_20 DNA alkylation repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 373.0
HKD1_k127_4333529_21 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 340.0
HKD1_k127_4333529_22 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 336.0
HKD1_k127_4333529_23 Diphthamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 329.0
HKD1_k127_4333529_24 pfam nudix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 317.0
HKD1_k127_4333529_25 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 312.0
HKD1_k127_4333529_26 ABC transporter, ATP-binding protein K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 316.0
HKD1_k127_4333529_27 Coat F domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002206 239.0
HKD1_k127_4333529_28 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000002751 238.0
HKD1_k127_4333529_29 Domain of unknown function (DUF4363) - - - 0.000000000000000000000000000000000000000000000001455 176.0
HKD1_k127_4333529_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 3.086e-287 885.0
HKD1_k127_4333529_30 acetyl-CoA hydrolase K18122 - - 0.0000000000000000000001121 98.0
HKD1_k127_4333529_31 Peptidase family S41 - - - 0.0000000003412 61.0
HKD1_k127_4333529_32 TIGRFAM Protein of - - - 0.0000000103 60.0
HKD1_k127_4333529_33 peptidase M24 K01262 - 3.4.11.9 0.0000000904 54.0
HKD1_k127_4333529_4 Diguanylate cyclase - - - 4.773e-261 815.0
HKD1_k127_4333529_5 amino acid peptide transporter - - - 5.033e-233 728.0
HKD1_k127_4333529_6 Transcriptional regulator - - - 1.484e-213 670.0
HKD1_k127_4333529_7 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 3.717e-211 664.0
HKD1_k127_4333529_8 Carbohydrate-binding domain-containing protein Cthe_2159 - GO:0001871,GO:0003674,GO:0005488,GO:0005509,GO:0030246,GO:0030247,GO:0030248,GO:0043167,GO:0043169,GO:0046872,GO:0048028,GO:2001062 - 2.357e-196 631.0
HKD1_k127_4333529_9 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 594.0
HKD1_k127_4591991_0 Subtilase family - - - 0.0 1374.0
HKD1_k127_4591991_1 Subtilase family - - - 8.969e-265 822.0
HKD1_k127_4591991_2 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 311.0
HKD1_k127_4591991_3 Subtilase family - - - 0.00000000000000000000000000004869 119.0
HKD1_k127_4776192_0 Zn-dependent metallo-hydrolase RNA specificity domain - - - 0.0 1049.0
HKD1_k127_4776192_1 heat shock protein 70 K04043 - - 0.0 1032.0
HKD1_k127_4776192_2 - - - - 2.723e-300 926.0
HKD1_k127_4776192_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 2.359e-219 687.0
HKD1_k127_4776192_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 553.0
HKD1_k127_4776192_5 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 545.0
HKD1_k127_4776192_6 Serine dehydratase beta chain K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 412.0
HKD1_k127_4776192_7 Helix-hairpin-helix motif K02237 - - 0.000000000005528 68.0
HKD1_k127_4776192_8 - - - - 0.00000001487 59.0
HKD1_k127_4784495_0 Acetyl-CoA carboxylase, biotin carboxylase subunit K01961 - 6.3.4.14,6.4.1.2 2.191e-266 823.0
HKD1_k127_4784495_1 Belongs to the 'phage' integrase family K03733 - - 1.077e-218 682.0
HKD1_k127_4784495_10 Oxidoreductase, short chain dehydrogenase reductase family protein K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 436.0
HKD1_k127_4784495_11 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 372.0
HKD1_k127_4784495_12 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 303.0
HKD1_k127_4784495_13 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 295.0
HKD1_k127_4784495_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001805 234.0
HKD1_k127_4784495_15 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000000000000002352 229.0
HKD1_k127_4784495_16 - - - - 0.000000000000000000000000000000000000000000001813 167.0
HKD1_k127_4784495_17 Protein of unknown function DUF134 K06933 - - 0.000000000000000000000000000000000000000000002 167.0
HKD1_k127_4784495_18 Small acid-soluble spore protein H family - - - 0.000000000000000000000005035 103.0
HKD1_k127_4784495_2 MotA/TolQ/ExbB proton channel family - - - 1.506e-217 684.0
HKD1_k127_4784495_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 9.277e-212 665.0
HKD1_k127_4784495_4 Histidine kinase - - - 7.568e-194 610.0
HKD1_k127_4784495_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 553.0
HKD1_k127_4784495_6 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 557.0
HKD1_k127_4784495_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 552.0
HKD1_k127_4784495_8 Phosphorylase superfamily K03784 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 447.0
HKD1_k127_4784495_9 S4 RNA-binding domain K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 437.0
HKD1_k127_4864916_0 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 476.0
HKD1_k127_4864916_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 474.0
HKD1_k127_4864916_2 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 412.0
HKD1_k127_4864916_3 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 367.0
HKD1_k127_4864916_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 281.0
HKD1_k127_4864916_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003802 250.0
HKD1_k127_4981265_0 CoA-substrate-specific enzyme activase - - - 0.0 2399.0
HKD1_k127_4981265_1 Psort location Cytoplasmic, score - - - 1.446e-267 826.0
HKD1_k127_4981265_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 441.0
HKD1_k127_4981265_11 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 436.0
HKD1_k127_4981265_12 Histidyl-tRNA synthetase K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 393.0
HKD1_k127_4981265_13 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 348.0
HKD1_k127_4981265_14 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 345.0
HKD1_k127_4981265_15 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 331.0
HKD1_k127_4981265_16 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 321.0
HKD1_k127_4981265_17 Histidine biosynthesis protein K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 294.0
HKD1_k127_4981265_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000127 234.0
HKD1_k127_4981265_19 Transcriptional regulator K07979 - - 0.00000000000000000000000000000000000000000000000000000000000000002654 225.0
HKD1_k127_4981265_2 Belongs to the methyltransferase superfamily K07444 - - 1.297e-239 741.0
HKD1_k127_4981265_20 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000001326 214.0
HKD1_k127_4981265_21 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000007586 199.0
HKD1_k127_4981265_22 L,D-transpeptidase catalytic domain K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000001333 193.0
HKD1_k127_4981265_23 - - - - 0.0000000000000000000000000000000000000000000001013 177.0
HKD1_k127_4981265_24 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000001777 158.0
HKD1_k127_4981265_25 - - - - 0.000000000000000000000000000000000005137 138.0
HKD1_k127_4981265_26 - - - - 0.00000000000000000000000000001228 119.0
HKD1_k127_4981265_27 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000005081 117.0
HKD1_k127_4981265_28 - - - - 0.0000000000000000000000000004383 117.0
HKD1_k127_4981265_29 - - - - 0.000000000000000000003518 93.0
HKD1_k127_4981265_3 Transporter gate domain protein - - - 2.14e-215 672.0
HKD1_k127_4981265_30 - - - - 0.0000000000000008756 78.0
HKD1_k127_4981265_31 Excinuclease ABC C subunit domain protein K07461 - - 0.00000000000000237 78.0
HKD1_k127_4981265_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 8.282e-209 655.0
HKD1_k127_4981265_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 1.804e-204 638.0
HKD1_k127_4981265_6 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 532.0
HKD1_k127_4981265_7 Queuosine biosynthesis protein QueC K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 486.0
HKD1_k127_4981265_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 486.0
HKD1_k127_4981265_9 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 465.0
HKD1_k127_5008604_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 2036.0
HKD1_k127_5008604_1 His Kinase A (phosphoacceptor) domain - - - 0.0 1772.0
HKD1_k127_5008604_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.208e-231 728.0
HKD1_k127_5104707_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 1.613e-274 846.0
HKD1_k127_5104707_1 Putative peptidoglycan binding domain - - - 1.481e-255 790.0
HKD1_k127_5104707_10 Ser Thr phosphatase family protein K07099 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 460.0
HKD1_k127_5104707_11 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 441.0
HKD1_k127_5104707_12 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 435.0
HKD1_k127_5104707_13 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 406.0
HKD1_k127_5104707_14 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 400.0
HKD1_k127_5104707_15 Protease prsW family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 376.0
HKD1_k127_5104707_16 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 321.0
HKD1_k127_5104707_17 Belongs to the 5'(3')-deoxyribonucleotidase family K05967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 320.0
HKD1_k127_5104707_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 326.0
HKD1_k127_5104707_19 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004653 271.0
HKD1_k127_5104707_2 belongs to the iron- containing alcohol dehydrogenase family K04072 - 1.1.1.1,1.2.1.10 4.308e-236 732.0
HKD1_k127_5104707_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 262.0
HKD1_k127_5104707_21 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000001004 223.0
HKD1_k127_5104707_22 Domain of unknown function (DUF1904) - - - 0.00000000000000000000000000000000000000000000000000000000000004229 214.0
HKD1_k127_5104707_23 - - - - 0.000000000000000000000000000000000000000000000000000002435 192.0
HKD1_k127_5104707_24 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000002902 164.0
HKD1_k127_5104707_25 - - - - 0.00000000000000000000000000000000000000003569 152.0
HKD1_k127_5104707_26 Probable zinc-ribbon domain - - - 0.000000000000000000001428 94.0
HKD1_k127_5104707_3 Domain of unknown function (DUF4163) - - - 2.37e-220 691.0
HKD1_k127_5104707_4 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 2.36e-219 686.0
HKD1_k127_5104707_5 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 559.0
HKD1_k127_5104707_6 NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 508.0
HKD1_k127_5104707_7 RelA SpoT domain protein K07816 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 494.0
HKD1_k127_5104707_8 Metallo-beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 487.0
HKD1_k127_5104707_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 481.0
HKD1_k127_5134467_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001175 229.0
HKD1_k127_5134467_1 - - - - 0.0000000000000000000000000000002806 132.0
HKD1_k127_5134467_3 - - - - 0.000000009545 59.0
HKD1_k127_5134467_4 - - - - 0.0000000479 60.0
HKD1_k127_5163871_0 Histidine kinase - - - 3.048e-252 796.0
HKD1_k127_5163871_1 Mga helix-turn-helix domain K03491 - - 2.317e-244 769.0
HKD1_k127_5163871_10 - - - - 0.000000000000000000000000000000000000000000002136 166.0
HKD1_k127_5163871_11 Major Facilitator Superfamily - - - 0.000000000000000000000000000005648 120.0
HKD1_k127_5163871_12 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000001899 104.0
HKD1_k127_5163871_13 - - - - 0.0000000000000001079 83.0
HKD1_k127_5163871_2 amino acid carrier protein K03310 - - 4.627e-243 756.0
HKD1_k127_5163871_3 amino acid peptide transporter K03305 - - 3.831e-223 698.0
HKD1_k127_5163871_4 Phosphotransferase system, EIIC K02768,K02769,K02770 - 2.7.1.202 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 522.0
HKD1_k127_5163871_5 Fusaric acid resistance protein-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 471.0
HKD1_k127_5163871_6 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K00882 - 2.7.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009287 450.0
HKD1_k127_5163871_7 DMT(Drug metabolite transporter) superfamily permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 446.0
HKD1_k127_5163871_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 424.0
HKD1_k127_5163871_9 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000000000003177 183.0
HKD1_k127_5181999_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 4.427e-289 890.0
HKD1_k127_5181999_1 Orn Lys Arg decarboxylase, major domain protein K01585 - 4.1.1.19 1.409e-255 794.0
HKD1_k127_5181999_10 HD domain K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 361.0
HKD1_k127_5181999_11 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 351.0
HKD1_k127_5181999_12 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 348.0
HKD1_k127_5181999_13 Nucleoside recognition K06373 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 324.0
HKD1_k127_5181999_14 PFAM nucleoside recognition domain protein K06374 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 301.0
HKD1_k127_5181999_15 ABC transporter, ATP-binding protein K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000697 286.0
HKD1_k127_5181999_16 AsnC family K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007112 259.0
HKD1_k127_5181999_17 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000001067 123.0
HKD1_k127_5181999_18 Domain of unknown function (DUF378) K09779 - - 0.000000000000000000001481 94.0
HKD1_k127_5181999_2 PSP1 C-terminal domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 566.0
HKD1_k127_5181999_3 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 547.0
HKD1_k127_5181999_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 504.0
HKD1_k127_5181999_5 Methyltransferase domain K15460 - 2.1.1.223 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 494.0
HKD1_k127_5181999_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 418.0
HKD1_k127_5181999_7 ABC transporter, ATP-binding protein K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 415.0
HKD1_k127_5181999_8 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 374.0
HKD1_k127_5181999_9 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 374.0
HKD1_k127_5244272_0 exonuclease K07462 - - 0.0 1404.0
HKD1_k127_5244272_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1345.0
HKD1_k127_5244272_10 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 5.745e-202 631.0
HKD1_k127_5244272_11 membrane - - - 2.443e-201 635.0
HKD1_k127_5244272_12 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 488.0
HKD1_k127_5244272_13 Transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 446.0
HKD1_k127_5244272_14 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 442.0
HKD1_k127_5244272_15 Putative threonine/serine exporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 423.0
HKD1_k127_5244272_16 Uncharacterized protein family UPF0029 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 376.0
HKD1_k127_5244272_17 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 367.0
HKD1_k127_5244272_18 Metallo-beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 356.0
HKD1_k127_5244272_19 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 323.0
HKD1_k127_5244272_2 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.0 1129.0
HKD1_k127_5244272_20 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 323.0
HKD1_k127_5244272_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 287.0
HKD1_k127_5244272_22 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 280.0
HKD1_k127_5244272_23 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002606 280.0
HKD1_k127_5244272_24 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003384 252.0
HKD1_k127_5244272_25 Putative threonine/serine exporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009774 250.0
HKD1_k127_5244272_26 Psort location - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009229 241.0
HKD1_k127_5244272_27 Hydrolase, NUDIX family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002971 240.0
HKD1_k127_5244272_28 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.00000000000000000000000000000000000000000000000000000000000000009467 224.0
HKD1_k127_5244272_29 Protein of unknown function (DUF3792) - - - 0.0000000000000000000000000000000000000000000000000000000000002372 213.0
HKD1_k127_5244272_3 ABC1 family K03688 - - 1.98e-304 939.0
HKD1_k127_5244272_30 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000001752 204.0
HKD1_k127_5244272_31 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000003232 199.0
HKD1_k127_5244272_32 - - - - 0.00000000000000000000000000000000000000000000000000009736 191.0
HKD1_k127_5244272_33 - - - - 0.0000000000000000000000000000000000000000005108 160.0
HKD1_k127_5244272_34 Preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000000000000006782 155.0
HKD1_k127_5244272_35 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000000000000000001253 154.0
HKD1_k127_5244272_36 Domain of Unknown Function (DUF1540) - - - 0.0000000000000000000000000000000003092 134.0
HKD1_k127_5244272_37 Small, acid-soluble spore proteins, alpha/beta type - - - 0.0000000000000000000000000000002695 124.0
HKD1_k127_5244272_38 six-cysteine peptide - - - 0.0000000000000000000002796 96.0
HKD1_k127_5244272_39 SNARE associated Golgi protein - - - 0.000000002365 59.0
HKD1_k127_5244272_4 coproporphyrinogen III oxidase - - - 2.095e-289 892.0
HKD1_k127_5244272_5 Six-Cys-in-45 modification radical SAM protein K06871 - - 4.258e-281 866.0
HKD1_k127_5244272_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 2.89e-255 794.0
HKD1_k127_5244272_7 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 4.234e-244 755.0
HKD1_k127_5244272_8 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.353e-232 724.0
HKD1_k127_5244272_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 1.299e-203 635.0
HKD1_k127_5373386_0 - - - - 6.856e-244 762.0
HKD1_k127_5373386_1 sequence-specific DNA binding - - - 4.518e-236 735.0
HKD1_k127_5373386_10 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001791 275.0
HKD1_k127_5373386_11 VanZ-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001233 242.0
HKD1_k127_5373386_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001141 232.0
HKD1_k127_5373386_13 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000118 221.0
HKD1_k127_5373386_14 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000000000000000000000000000000000000029 218.0
HKD1_k127_5373386_16 - - - - 0.0000000000000000000000000000000000000000000000000000000001218 205.0
HKD1_k127_5373386_17 - - - - 0.000000000000000000000000000000000000000000000000000000007633 199.0
HKD1_k127_5373386_18 Domain of unknown function (DUF4825) - - - 0.00000000000000000000000000000000000000000000000004045 183.0
HKD1_k127_5373386_19 permease - - - 0.000000000000000000000000000000000000000000000000304 196.0
HKD1_k127_5373386_2 Cellulose biosynthesis protein BcsQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 507.0
HKD1_k127_5373386_20 Mor transcription activator family - - - 0.0000000000000000000000000000000000000000000005685 166.0
HKD1_k127_5373386_21 - - - - 0.0000000000000000000000000000000000000000005517 162.0
HKD1_k127_5373386_22 Filamentation induced by cAMP protein fic - - - 0.000000000000000000000000000000000000007935 146.0
HKD1_k127_5373386_23 - - - - 0.00000000000000000000000000000000000001547 146.0
HKD1_k127_5373386_25 Protein of unknown function (DUF2922) - - - 0.000000000000000000000000000000007675 128.0
HKD1_k127_5373386_26 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000000000000001268 126.0
HKD1_k127_5373386_27 - - - - 0.0000000000000000000000000000001145 124.0
HKD1_k127_5373386_28 - - - - 0.00000000000000000000000007076 113.0
HKD1_k127_5373386_29 Protein of unknown function (DUF1659) - - - 0.0000000000000000000000005058 106.0
HKD1_k127_5373386_3 ATPases associated with a variety of cellular activities K01990,K16907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 471.0
HKD1_k127_5373386_30 - - - - 0.00000000000000000000003599 101.0
HKD1_k127_5373386_32 - - - - 0.0000000000000000001077 93.0
HKD1_k127_5373386_34 Antirestriction protein (ArdA) - - - 0.0000000000001388 76.0
HKD1_k127_5373386_35 Cysteine-rich CPCC - - - 0.000000000000359 71.0
HKD1_k127_5373386_36 - - - - 0.0000000002065 65.0
HKD1_k127_5373386_37 - - - - 0.00000001304 59.0
HKD1_k127_5373386_39 - - - - 0.000002056 54.0
HKD1_k127_5373386_4 Resolvase, N terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 464.0
HKD1_k127_5373386_5 transposase or invertase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 404.0
HKD1_k127_5373386_6 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 346.0
HKD1_k127_5373386_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 302.0
HKD1_k127_5373386_8 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 301.0
HKD1_k127_5373386_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 296.0
HKD1_k127_5400505_0 conserved repeat domain protein - - - 0.0 3426.0
HKD1_k127_5400505_1 Belongs to the glycosyl hydrolase 13 family K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0 1013.0
HKD1_k127_5400505_10 capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 434.0
HKD1_k127_5400505_11 Cell envelope-like function transcriptional attenuator common domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 434.0
HKD1_k127_5400505_12 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 405.0
HKD1_k127_5400505_13 cell wall organization K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 372.0
HKD1_k127_5400505_14 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 349.0
HKD1_k127_5400505_15 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 343.0
HKD1_k127_5400505_16 UbiC transcription regulator-associated domain protein K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 324.0
HKD1_k127_5400505_17 Conserved repeat domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 316.0
HKD1_k127_5400505_18 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 304.0
HKD1_k127_5400505_19 Threonine/Serine exporter, ThrE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 308.0
HKD1_k127_5400505_2 Permease family K06901 - - 5.086e-229 715.0
HKD1_k127_5400505_20 Serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 297.0
HKD1_k127_5400505_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007865 267.0
HKD1_k127_5400505_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002975 229.0
HKD1_k127_5400505_23 PFAM Transposase, IS801 IS1294 - - - 0.00000000000000000000000000000000000000000000000000000000000000000427 227.0
HKD1_k127_5400505_24 Putative small multi-drug export protein - - - 0.0000000000000000000000000000000000000000000000000006287 188.0
HKD1_k127_5400505_26 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000001001 176.0
HKD1_k127_5400505_27 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000000000003554 168.0
HKD1_k127_5400505_28 Threonine/Serine exporter, ThrE - - - 0.00000000000000000000000000000000000000000427 160.0
HKD1_k127_5400505_29 - - - - 0.0000000000000000000000000000000000000006944 148.0
HKD1_k127_5400505_3 AI-2E family transporter - - - 3.553e-195 614.0
HKD1_k127_5400505_30 Protein of unknown function (DUF1294) - - - 0.0000000000000000000000004243 106.0
HKD1_k127_5400505_31 Membrane transport protein K07088 - - 0.000000000000000000009283 93.0
HKD1_k127_5400505_32 - - - - 0.000000000000007866 78.0
HKD1_k127_5400505_33 LysM domain - - - 0.00000000000002089 76.0
HKD1_k127_5400505_34 Belongs to the 'phage' integrase family - - - 0.00000000000005026 72.0
HKD1_k127_5400505_36 Putative cyclase - - - 0.00000002158 58.0
HKD1_k127_5400505_4 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 538.0
HKD1_k127_5400505_5 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 531.0
HKD1_k127_5400505_6 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 516.0
HKD1_k127_5400505_7 Protein of unknown function (DUF3810) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 521.0
HKD1_k127_5400505_8 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 498.0
HKD1_k127_5400505_9 pfkB family carbohydrate kinase K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 488.0
HKD1_k127_5413805_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.0 2188.0
HKD1_k127_5413805_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1787.0
HKD1_k127_5413805_10 Psort location Cytoplasmic, score K08602 - - 0.0 1062.0
HKD1_k127_5413805_100 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000003934 184.0
HKD1_k127_5413805_101 - - - - 0.00000000000000000000000000000000000000000000000001022 181.0
HKD1_k127_5413805_102 - - - - 0.000000000000000000000000000000000000000000000003236 177.0
HKD1_k127_5413805_103 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000000000000000000000000000000000000000000001809 168.0
HKD1_k127_5413805_104 TSCPD domain - - - 0.000000000000000000000000000000000000000005614 154.0
HKD1_k127_5413805_105 FMN-binding domain protein - - - 0.000000000000000000000000000000000000003092 162.0
HKD1_k127_5413805_106 ferrous iron transport protein K04758 - - 0.00000000000000000000000000000000003283 135.0
HKD1_k127_5413805_107 Domain of unknown function (DUF3899) - - - 0.0000000000000000000000000000000002251 135.0
HKD1_k127_5413805_108 Small, acid-soluble spore proteins, alpha/beta type - - - 0.0000000000000000000000000000001682 123.0
HKD1_k127_5413805_109 - K02663 - - 0.0000000000000000000000000000005833 127.0
HKD1_k127_5413805_11 Pyruvate kinase K00873 - 2.7.1.40 0.0 1045.0
HKD1_k127_5413805_110 - - - - 0.000000000000000000000000000002678 122.0
HKD1_k127_5413805_111 Bacterial protein of unknown function (DUF881) - - - 0.000000000000000000000000000002819 130.0
HKD1_k127_5413805_112 Spo0E like sporulation regulatory protein - - - 0.00000000000000000000001159 101.0
HKD1_k127_5413805_113 Prokaryotic N-terminal methylation motif K02650 - - 0.000000000000000000003297 96.0
HKD1_k127_5413805_115 Bacterial PH domain - - - 0.00000000000000000002585 92.0
HKD1_k127_5413805_116 PFAM Small, acid-soluble spore proteins, alpha beta type - - - 0.00000000000000004746 84.0
HKD1_k127_5413805_117 Prokaryotic N-terminal methylation motif K02650 - - 0.00000000000213 69.0
HKD1_k127_5413805_12 Sodium:neurotransmitter symporter family - - - 0.0 1014.0
HKD1_k127_5413805_121 - - - - 0.0002177 44.0
HKD1_k127_5413805_13 'oxidoreductase K07137 - - 1.05e-321 987.0
HKD1_k127_5413805_14 Sigma-54 interaction domain protein - - - 1.183e-320 987.0
HKD1_k127_5413805_15 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 5.19e-312 966.0
HKD1_k127_5413805_16 Family 5 K15580 - - 7.429e-292 902.0
HKD1_k127_5413805_17 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 2.968e-288 888.0
HKD1_k127_5413805_18 Belongs to the GPI family K01810 - 5.3.1.9 2.079e-282 869.0
HKD1_k127_5413805_19 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 9.106e-281 865.0
HKD1_k127_5413805_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1763.0
HKD1_k127_5413805_20 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 2.083e-277 855.0
HKD1_k127_5413805_21 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 1.835e-267 826.0
HKD1_k127_5413805_22 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 6.144e-254 785.0
HKD1_k127_5413805_23 Folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 2.425e-247 767.0
HKD1_k127_5413805_24 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 3.042e-243 755.0
HKD1_k127_5413805_25 PFAM amine oxidase K00274 - 1.4.3.4 8.328e-243 762.0
HKD1_k127_5413805_26 electron transport complex protein RnfC K03615 - - - 3.846e-235 730.0
HKD1_k127_5413805_27 Belongs to the UPF0597 family - - - 1.728e-234 730.0
HKD1_k127_5413805_28 RNA polymerase K03092 - - 6.321e-233 726.0
HKD1_k127_5413805_29 Type II IV secretion system protein K02454,K02652 - - 1.017e-230 720.0
HKD1_k127_5413805_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1415.0
HKD1_k127_5413805_30 Bacterial regulatory protein, Fis family - - - 3.803e-222 694.0
HKD1_k127_5413805_31 Required for morphogenesis under gluconeogenic growth conditions - - - 2.584e-218 679.0
HKD1_k127_5413805_32 Belongs to the ABC transporter superfamily K15583 - - 3.205e-204 637.0
HKD1_k127_5413805_33 Mo-molybdopterin cofactor biosynthetic process - - - 6.725e-203 634.0
HKD1_k127_5413805_34 Psort location Cytoplasmic, score 8.87 K05823 - 3.5.1.47 8.402e-202 632.0
HKD1_k127_5413805_35 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15582 - - 4.538e-201 628.0
HKD1_k127_5413805_36 Proline racemase K01777 - 5.1.1.4 9.268e-201 627.0
HKD1_k127_5413805_37 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 2.868e-198 619.0
HKD1_k127_5413805_38 SEC-C motif - - - 1.649e-195 614.0
HKD1_k127_5413805_39 MacB-like periplasmic core domain K02004 - - 2.963e-195 615.0
HKD1_k127_5413805_4 COG COG1894 NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335,K18331 - 1.12.1.3,1.6.5.3 0.0 1219.0
HKD1_k127_5413805_40 Trypsin-like peptidase domain K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 606.0
HKD1_k127_5413805_41 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 598.0
HKD1_k127_5413805_42 Putative sugar-binding domain K05311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 594.0
HKD1_k127_5413805_43 May be required for sporulation K09762 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 574.0
HKD1_k127_5413805_44 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 554.0
HKD1_k127_5413805_45 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 548.0
HKD1_k127_5413805_46 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 544.0
HKD1_k127_5413805_47 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 538.0
HKD1_k127_5413805_48 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 535.0
HKD1_k127_5413805_49 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 533.0
HKD1_k127_5413805_5 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1209.0
HKD1_k127_5413805_50 Bacterial type II secretion system K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 527.0
HKD1_k127_5413805_51 Binding-protein-dependent transport system inner membrane component K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 522.0
HKD1_k127_5413805_52 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 511.0
HKD1_k127_5413805_53 Formate/nitrite transporter K21993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 504.0
HKD1_k127_5413805_54 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 501.0
HKD1_k127_5413805_55 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 503.0
HKD1_k127_5413805_56 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 494.0
HKD1_k127_5413805_57 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 491.0
HKD1_k127_5413805_58 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 480.0
HKD1_k127_5413805_59 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007654 475.0
HKD1_k127_5413805_6 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0 1164.0
HKD1_k127_5413805_60 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 474.0
HKD1_k127_5413805_61 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 467.0
HKD1_k127_5413805_62 Mechanosensitive ion channel K22044 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 455.0
HKD1_k127_5413805_63 GHKL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 460.0
HKD1_k127_5413805_64 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 452.0
HKD1_k127_5413805_65 Belongs to the ABC transporter superfamily K10823 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 451.0
HKD1_k127_5413805_66 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 447.0
HKD1_k127_5413805_67 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 446.0
HKD1_k127_5413805_68 Glycine/sarcosine/betaine reductase component B subunits K10793,K10795 - 1.21.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 439.0
HKD1_k127_5413805_69 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 430.0
HKD1_k127_5413805_7 Psort location Cytoplasmic, score K00336,K18332 - 1.12.1.3,1.6.5.3 0.0 1121.0
HKD1_k127_5413805_70 Formate/nitrite transporter K21993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 425.0
HKD1_k127_5413805_71 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate K00674,K05822 - 2.3.1.117,2.3.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 422.0
HKD1_k127_5413805_72 DNA polymerase alpha chain like domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 415.0
HKD1_k127_5413805_73 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 403.0
HKD1_k127_5413805_74 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 394.0
HKD1_k127_5413805_75 PFAM single-strand binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 392.0
HKD1_k127_5413805_76 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 390.0
HKD1_k127_5413805_77 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 389.0
HKD1_k127_5413805_78 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 375.0
HKD1_k127_5413805_79 4Fe-4S binding domain K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 375.0
HKD1_k127_5413805_8 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0 1103.0
HKD1_k127_5413805_80 YvbH-like oligomerisation region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 363.0
HKD1_k127_5413805_81 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 362.0
HKD1_k127_5413805_82 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 362.0
HKD1_k127_5413805_83 Fusaric acid resistance protein-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 360.0
HKD1_k127_5413805_84 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 352.0
HKD1_k127_5413805_85 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 347.0
HKD1_k127_5413805_86 Domain of unknown function (DUF4364) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 335.0
HKD1_k127_5413805_87 Domain of unknown function (DUF4397) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 309.0
HKD1_k127_5413805_88 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 301.0
HKD1_k127_5413805_89 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 301.0
HKD1_k127_5413805_9 D-proline reductase K10793 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046992,GO:0050002,GO:0050485,GO:0055114 1.21.4.1 0.0 1091.0
HKD1_k127_5413805_90 Pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 302.0
HKD1_k127_5413805_91 Glycine/sarcosine/betaine reductase component B subunits K10796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 284.0
HKD1_k127_5413805_92 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 280.0
HKD1_k127_5413805_93 Phosphoesterase K07095 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001633 258.0
HKD1_k127_5413805_94 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005642 232.0
HKD1_k127_5413805_95 Response regulator of the LytR AlgR family - - - 0.000000000000000000000000000000000000000000000000000000000000003639 224.0
HKD1_k127_5413805_96 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000005225 219.0
HKD1_k127_5413805_97 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000004061 222.0
HKD1_k127_5413805_98 - - - - 0.00000000000000000000000000000000000000000000000000000002763 203.0
HKD1_k127_5413805_99 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000006428 199.0
HKD1_k127_5425989_0 AAA domain - - - 0.0 1380.0
HKD1_k127_5425989_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 1.024e-305 939.0
HKD1_k127_5425989_10 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 322.0
HKD1_k127_5425989_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 299.0
HKD1_k127_5425989_12 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002518 275.0
HKD1_k127_5425989_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006044 265.0
HKD1_k127_5425989_14 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000000000000000000000000000000002729 233.0
HKD1_k127_5425989_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000007756 234.0
HKD1_k127_5425989_16 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000000000000000001568 219.0
HKD1_k127_5425989_17 ATP synthase I chain - - - 0.0000000000000000000000000000000000000000000000000004368 186.0
HKD1_k127_5425989_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000007974 166.0
HKD1_k127_5425989_19 - - - - 0.00000000000000000000000000000000006335 134.0
HKD1_k127_5425989_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 5.423e-283 871.0
HKD1_k127_5425989_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000004112 126.0
HKD1_k127_5425989_21 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000000000000000000000000000005531 126.0
HKD1_k127_5425989_22 Ribbon-helix-helix protein, copG family K07723 - - 0.000000000000003214 79.0
HKD1_k127_5425989_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.566e-210 658.0
HKD1_k127_5425989_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 2.466e-205 643.0
HKD1_k127_5425989_5 Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 567.0
HKD1_k127_5425989_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 472.0
HKD1_k127_5425989_7 Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 470.0
HKD1_k127_5425989_8 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 379.0
HKD1_k127_5425989_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 329.0
HKD1_k127_5435129_0 Belongs to the carbamoyltransferase HypF family K04656 - - 2.873e-279 877.0
HKD1_k127_5435129_1 import. Responsible for energy coupling to the transport system K10441,K10542 - 3.6.3.17 5.665e-264 820.0
HKD1_k127_5435129_10 hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 445.0
HKD1_k127_5435129_11 Nitrite and sulphite reductase 4Fe-4S domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 406.0
HKD1_k127_5435129_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 356.0
HKD1_k127_5435129_13 Domain of unknown function (DUF4163) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 353.0
HKD1_k127_5435129_14 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 329.0
HKD1_k127_5435129_15 methyl-accepting chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 332.0
HKD1_k127_5435129_16 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 295.0
HKD1_k127_5435129_17 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004228 259.0
HKD1_k127_5435129_18 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001781 256.0
HKD1_k127_5435129_19 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002393 257.0
HKD1_k127_5435129_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 5.475e-250 781.0
HKD1_k127_5435129_20 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose K06726 - 5.4.99.62 0.00000000000000000000000000000000000000000000000000000000000042 212.0
HKD1_k127_5435129_21 - - - - 0.0000000000000000000000000000000000000000000000000000001682 195.0
HKD1_k127_5435129_22 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000001532 159.0
HKD1_k127_5435129_23 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000000001279 141.0
HKD1_k127_5435129_24 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000000001174 138.0
HKD1_k127_5435129_25 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000001255 141.0
HKD1_k127_5435129_26 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000000003801 113.0
HKD1_k127_5435129_27 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000000000001011 104.0
HKD1_k127_5435129_28 - - - - 0.000000004148 57.0
HKD1_k127_5435129_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 2.169e-241 758.0
HKD1_k127_5435129_4 helicase superfamily c-terminal domain K11927 - 3.6.4.13 1.633e-223 699.0
HKD1_k127_5435129_5 Transcriptional regulator, LacI family K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 572.0
HKD1_k127_5435129_6 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 496.0
HKD1_k127_5435129_7 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 477.0
HKD1_k127_5435129_8 PFAM AIR synthase related protein K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 464.0
HKD1_k127_5435129_9 PFAM periplasmic binding protein K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 451.0
HKD1_k127_5483128_0 FtsX-like permease family K02004 - - 3.666e-247 779.0
HKD1_k127_5483128_1 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) K07862 - - 2.245e-236 734.0
HKD1_k127_5483128_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 263.0
HKD1_k127_5483128_11 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005413 266.0
HKD1_k127_5483128_12 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000003545 230.0
HKD1_k127_5483128_13 FMN-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000007712 198.0
HKD1_k127_5483128_14 - - - - 0.000000000000000000000000000117 119.0
HKD1_k127_5483128_15 membrane - - - 0.0000000000000000002048 88.0
HKD1_k127_5483128_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 569.0
HKD1_k127_5483128_3 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 499.0
HKD1_k127_5483128_4 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 442.0
HKD1_k127_5483128_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 400.0
HKD1_k127_5483128_6 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 372.0
HKD1_k127_5483128_7 Acetyltransferase (GNAT) domain K06323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 366.0
HKD1_k127_5483128_8 4Fe-4S binding domain K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 361.0
HKD1_k127_5483128_9 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 317.0
HKD1_k127_5486668_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1305.0
HKD1_k127_5486668_1 hmm pf01447 K01400 - 3.4.24.28 0.0 1126.0
HKD1_k127_5486668_10 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 3.599e-252 781.0
HKD1_k127_5486668_11 Psort location Cytoplasmic, score K07007 - - 7.543e-240 744.0
HKD1_k127_5486668_12 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 2.895e-238 740.0
HKD1_k127_5486668_13 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 9.311e-238 744.0
HKD1_k127_5486668_14 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 3.764e-235 729.0
HKD1_k127_5486668_15 Patatin-like phospholipase K07001 - - 1.35e-229 714.0
HKD1_k127_5486668_16 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - 1.4e-223 696.0
HKD1_k127_5486668_17 cell wall organization - - - 9.377e-219 717.0
HKD1_k127_5486668_18 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 2.273e-215 675.0
HKD1_k127_5486668_19 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 3.069e-207 647.0
HKD1_k127_5486668_2 Glycosyl hydrolase-like 10 - - - 0.0 1101.0
HKD1_k127_5486668_20 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.461e-206 653.0
HKD1_k127_5486668_21 UDP-glucose 4-epimerase K01784 - 5.1.3.2 2.405e-200 626.0
HKD1_k127_5486668_22 Aminotransferase class I and II K04720 - 4.1.1.81 2.506e-198 621.0
HKD1_k127_5486668_23 aspartate--ammonia ligase K01914 - 6.3.1.1 2.608e-195 611.0
HKD1_k127_5486668_24 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 580.0
HKD1_k127_5486668_25 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 570.0
HKD1_k127_5486668_26 Phosphotransferase system, EIIC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 565.0
HKD1_k127_5486668_27 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 548.0
HKD1_k127_5486668_28 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 551.0
HKD1_k127_5486668_29 Cell envelope-like function transcriptional attenuator common domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 528.0
HKD1_k127_5486668_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0 1022.0
HKD1_k127_5486668_30 Group 1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 531.0
HKD1_k127_5486668_31 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 528.0
HKD1_k127_5486668_32 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 509.0
HKD1_k127_5486668_33 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 509.0
HKD1_k127_5486668_34 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 505.0
HKD1_k127_5486668_35 PAP2 superfamily K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 495.0
HKD1_k127_5486668_36 Glycosyltransferase, group 2 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 484.0
HKD1_k127_5486668_37 Glycosyltransferase like family 2 K12997,K16698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 452.0
HKD1_k127_5486668_38 Capsular polysaccharide synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 442.0
HKD1_k127_5486668_39 undecaprenyl K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 423.0
HKD1_k127_5486668_4 Ami_3 K01448 - 3.5.1.28 6.4e-323 998.0
HKD1_k127_5486668_40 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 418.0
HKD1_k127_5486668_41 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 381.0
HKD1_k127_5486668_42 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 370.0
HKD1_k127_5486668_43 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate K15024 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 364.0
HKD1_k127_5486668_44 NlpC/P60 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 361.0
HKD1_k127_5486668_45 Putative cell wall binding repeat 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 362.0
HKD1_k127_5486668_46 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 352.0
HKD1_k127_5486668_47 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 352.0
HKD1_k127_5486668_48 cell wall organization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 349.0
HKD1_k127_5486668_49 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 320.0
HKD1_k127_5486668_5 Stage II sporulation protein E K07315 - 3.1.3.3 1.632e-316 975.0
HKD1_k127_5486668_50 Putative amidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 310.0
HKD1_k127_5486668_51 cell wall binding repeat 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002735 301.0
HKD1_k127_5486668_52 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000004721 269.0
HKD1_k127_5486668_53 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002319 249.0
HKD1_k127_5486668_54 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000441 247.0
HKD1_k127_5486668_55 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000008441 240.0
HKD1_k127_5486668_56 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000001565 232.0
HKD1_k127_5486668_57 cell wall binding repeat 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000008599 243.0
HKD1_k127_5486668_58 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000000000000002229 199.0
HKD1_k127_5486668_59 COG COG0791 Cell wall-associated hydrolases (invasion-associated proteins) K13694,K19224,K21471 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000001168 204.0
HKD1_k127_5486668_6 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 3.064e-307 948.0
HKD1_k127_5486668_60 - - - - 0.00000000000000000000000000000000000000000000000007268 179.0
HKD1_k127_5486668_61 HPr family K02784,K11189 - - 0.0000000000000000000000000000000000000003109 150.0
HKD1_k127_5486668_62 Toxin ToxN, type III toxin-antitoxin system - - - 0.000000000000000000000000000000000000001903 153.0
HKD1_k127_5486668_63 'small, acid-soluble spore protein K06418,K06419,K06420,K06421 - - 0.00000000000000000000000000000001628 126.0
HKD1_k127_5486668_64 - - - - 0.000000000000000000000000009176 109.0
HKD1_k127_5486668_65 S-layer homology domain - - - 0.0000000000000000000000144 117.0
HKD1_k127_5486668_68 Glycosyl transferases group 1 - - - 0.000003196 50.0
HKD1_k127_5486668_7 TaqI-like C-terminal specificity domain K07317 - 2.1.1.72 7.129e-276 858.0
HKD1_k127_5486668_70 Beta-lactamase enzyme family - - - 0.00001208 48.0
HKD1_k127_5486668_8 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 8.607e-266 820.0
HKD1_k127_5486668_9 membrane protein involved in D-alanine export K19294 - - 1.715e-252 784.0
HKD1_k127_5488215_0 Protein of unknown function (DUF3800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002555 258.0
HKD1_k127_5488215_1 Host cell surface-exposed lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000676 218.0
HKD1_k127_5488215_2 n-acetylmuramoyl-l-alanine amidase - - - 0.00000000000000000000000000000000000000000000000000002045 196.0
HKD1_k127_5488215_3 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000000000003685 161.0
HKD1_k127_5488215_4 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000009447 92.0
HKD1_k127_5488215_6 Bacteriophage holin family - - - 0.00001723 51.0
HKD1_k127_5500613_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1534.0
HKD1_k127_5500613_1 Belongs to the sulfur carrier protein TusA family - - - 0.0 1287.0
HKD1_k127_5500613_10 phosphoglycerate mutase K02226,K22305 - 3.1.3.3,3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 387.0
HKD1_k127_5500613_11 Belongs to the arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 388.0
HKD1_k127_5500613_12 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 369.0
HKD1_k127_5500613_13 TraX protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 357.0
HKD1_k127_5500613_14 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 351.0
HKD1_k127_5500613_15 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 339.0
HKD1_k127_5500613_16 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 315.0
HKD1_k127_5500613_17 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 307.0
HKD1_k127_5500613_18 PFAM Cyclic nucleotide-binding K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 295.0
HKD1_k127_5500613_19 6,7-dimethyl-8-ribityllumazine synthase K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 287.0
HKD1_k127_5500613_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0 1255.0
HKD1_k127_5500613_20 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005475 238.0
HKD1_k127_5500613_21 Belongs to the GPAT DAPAT family - - - 0.000000000000000000000000000000000000000000000000000000000000000007632 228.0
HKD1_k127_5500613_22 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000419 203.0
HKD1_k127_5500613_23 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis K06208 - 5.4.99.5 0.00000000000000000000000000000000000000000000000000000004432 198.0
HKD1_k127_5500613_24 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000000000000005954 177.0
HKD1_k127_5500613_25 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000003625 153.0
HKD1_k127_5500613_28 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000003031 92.0
HKD1_k127_5500613_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 5.794e-262 812.0
HKD1_k127_5500613_4 HI0933-like protein K07007 - - 5.461e-229 712.0
HKD1_k127_5500613_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.006e-226 706.0
HKD1_k127_5500613_6 Cation diffusion facilitator family transporter - - - 2.604e-211 661.0
HKD1_k127_5500613_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 603.0
HKD1_k127_5500613_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 509.0
HKD1_k127_5500613_9 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 461.0
HKD1_k127_5587209_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1242.0
HKD1_k127_5587209_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 2.962e-306 942.0
HKD1_k127_5587209_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.068e-261 808.0
HKD1_k127_5587209_3 phosphoglycerate kinase K00927,K01803 - 2.7.2.3,5.3.1.1 1.514e-244 757.0
HKD1_k127_5587209_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 477.0
HKD1_k127_5587209_5 NB-ARC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 460.0
HKD1_k127_5587209_6 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 287.0
HKD1_k127_5587209_7 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000001728 224.0
HKD1_k127_5587209_8 - - - - 0.000000000000000000000000000000000000000000000007222 173.0
HKD1_k127_5587209_9 Preprotein translocase, SecG subunit K03075 - - 0.0000000000000000000000000000001652 124.0
HKD1_k127_5717678_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 2130.0
HKD1_k127_5717678_1 Belongs to the ClpA ClpB family K03696 - - 0.0 1374.0
HKD1_k127_5717678_10 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 469.0
HKD1_k127_5717678_11 Belongs to the sigma-70 factor family K03091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 398.0
HKD1_k127_5717678_12 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 387.0
HKD1_k127_5717678_13 Psort location Cytoplasmic, score K06962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 323.0
HKD1_k127_5717678_14 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 301.0
HKD1_k127_5717678_15 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) K11145 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004717 238.0
HKD1_k127_5717678_16 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000002797 79.0
HKD1_k127_5717678_17 - - - - 0.000000000000003695 76.0
HKD1_k127_5717678_2 Elongation factor K02355 - - 0.0 1174.0
HKD1_k127_5717678_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0 1059.0
HKD1_k127_5717678_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 4.325e-311 955.0
HKD1_k127_5717678_5 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.095e-284 877.0
HKD1_k127_5717678_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 7.846e-282 869.0
HKD1_k127_5717678_7 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation K07067 - 2.7.7.85 4.656e-203 634.0
HKD1_k127_5717678_8 PIN domain protein - - - 6.271e-200 626.0
HKD1_k127_5717678_9 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 474.0
HKD1_k127_5782264_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 5.727e-266 820.0
HKD1_k127_5782264_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 282.0
HKD1_k127_5849793_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 2043.0
HKD1_k127_5849793_1 Required for chromosome condensation and partitioning K03529 - - 0.0 1825.0
HKD1_k127_5849793_10 Psort location Cytoplasmic, score - - - 0.0 1043.0
HKD1_k127_5849793_100 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 387.0
HKD1_k127_5849793_101 thiamine K00949 - 2.7.6.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 376.0
HKD1_k127_5849793_102 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 372.0
HKD1_k127_5849793_103 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 352.0
HKD1_k127_5849793_104 DeoR-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 332.0
HKD1_k127_5849793_105 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 332.0
HKD1_k127_5849793_106 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 330.0
HKD1_k127_5849793_107 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 323.0
HKD1_k127_5849793_108 SpoIIIAH-like protein K06397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 324.0
HKD1_k127_5849793_109 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 321.0
HKD1_k127_5849793_11 May be involved in recombinational repair of damaged DNA K03631 - - 9.256e-315 969.0
HKD1_k127_5849793_110 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 319.0
HKD1_k127_5849793_111 - K06384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 318.0
HKD1_k127_5849793_112 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 316.0
HKD1_k127_5849793_113 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 303.0
HKD1_k127_5849793_114 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 301.0
HKD1_k127_5849793_115 Stage III sporulation protein AF (Spore_III_AF) K06395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 299.0
HKD1_k127_5849793_116 negative regulation of DNA recombination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 296.0
HKD1_k127_5849793_117 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 311.0
HKD1_k127_5849793_118 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 280.0
HKD1_k127_5849793_119 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004056 274.0
HKD1_k127_5849793_12 DAK2 domain fusion protein YloV K07030 - - 3.595e-311 957.0
HKD1_k127_5849793_120 Flavodoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001041 274.0
HKD1_k127_5849793_121 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006322 271.0
HKD1_k127_5849793_122 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001436 267.0
HKD1_k127_5849793_123 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001852 266.0
HKD1_k127_5849793_124 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002315 263.0
HKD1_k127_5849793_125 Stage III sporulation protein AG K06396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008784 254.0
HKD1_k127_5849793_126 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001013 247.0
HKD1_k127_5849793_127 Divergent PAP2 family K09775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003703 245.0
HKD1_k127_5849793_128 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000441 247.0
HKD1_k127_5849793_129 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000000000000007221 234.0
HKD1_k127_5849793_13 Mg chelatase-like protein K07391 - - 9.132e-296 912.0
HKD1_k127_5849793_130 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000002621 235.0
HKD1_k127_5849793_131 Asp23 family, cell envelope-related function - - - 0.0000000000000000000000000000000000000000000000000000000000000000135 225.0
HKD1_k127_5849793_132 Stage III sporulation protein AC/AD protein family K06393 - - 0.00000000000000000000000000000000000000000000000000000000000000006354 223.0
HKD1_k127_5849793_133 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein K09787 - - 0.0000000000000000000000000000000000000000000000000000000000000001395 222.0
HKD1_k127_5849793_134 - - - - 0.000000000000000000000000000000000000000000000000000000000000002486 223.0
HKD1_k127_5849793_135 - - - - 0.000000000000000000000000000000000000000000000000000000000000002558 218.0
HKD1_k127_5849793_136 Stage III sporulation protein AB (spore_III_AB) K06391 - - 0.000000000000000000000000000000000000000000000000000000000002639 213.0
HKD1_k127_5849793_137 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000000000000000000000000000000000006064 206.0
HKD1_k127_5849793_138 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000000000000000000000000000001387 201.0
HKD1_k127_5849793_139 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000002693 191.0
HKD1_k127_5849793_14 Sodium:alanine symporter family K03310 - - 4.3e-288 889.0
HKD1_k127_5849793_140 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000000000000000000004132 184.0
HKD1_k127_5849793_141 - - - - 0.0000000000000000000000000000000000000000000000002454 177.0
HKD1_k127_5849793_142 Belongs to the UPF0297 family - - - 0.0000000000000000000000000000000000000000005987 158.0
HKD1_k127_5849793_143 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000000000000000001704 156.0
HKD1_k127_5849793_144 YGGT family K02221 - - 0.0000000000000000000000000000000000006662 140.0
HKD1_k127_5849793_145 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000761 137.0
HKD1_k127_5849793_146 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000000000009015 131.0
HKD1_k127_5849793_147 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.000000000000000000000000000000001238 136.0
HKD1_k127_5849793_148 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000001451 129.0
HKD1_k127_5849793_149 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000001282 127.0
HKD1_k127_5849793_15 Penicillin binding protein transpeptidase domain K05515 - 3.4.16.4 3.111e-286 887.0
HKD1_k127_5849793_150 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000000003535 124.0
HKD1_k127_5849793_151 Stage III sporulation protein AC/AD protein family K06392 - - 0.00000000000000000000000000000006501 124.0
HKD1_k127_5849793_152 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000000000001983 121.0
HKD1_k127_5849793_153 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000003063 120.0
HKD1_k127_5849793_154 transcription antitermination K03625 - - 0.000000000000000000001968 101.0
HKD1_k127_5849793_155 - - - - 0.000000000000000000891 87.0
HKD1_k127_5849793_156 mannose-6-phosphate isomerase, class I - - - 0.000000000000002591 76.0
HKD1_k127_5849793_157 Copper amine oxidase N-terminal domain - - - 0.0004171 51.0
HKD1_k127_5849793_16 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.291e-281 869.0
HKD1_k127_5849793_17 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 7.357e-272 839.0
HKD1_k127_5849793_18 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 2.679e-270 834.0
HKD1_k127_5849793_19 L-lactate permease K03303 - - 2.519e-264 821.0
HKD1_k127_5849793_2 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1585.0
HKD1_k127_5849793_20 Psort location CytoplasmicMembrane, score K12132 - 2.7.11.1 4.562e-263 820.0
HKD1_k127_5849793_21 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 6.162e-249 770.0
HKD1_k127_5849793_22 pyrimidine-nucleoside phosphorylase K00756,K00758 - 2.4.2.2,2.4.2.4 6.451e-246 763.0
HKD1_k127_5849793_23 electron transfer flavoprotein K03522 - - 3.204e-242 750.0
HKD1_k127_5849793_24 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1 1.411e-241 748.0
HKD1_k127_5849793_25 His Kinase A (phosphoacceptor) domain - - - 1.441e-240 768.0
HKD1_k127_5849793_26 Psort location Cytoplasmic, score 8.87 K22373 - 5.1.2.1 2.067e-240 747.0
HKD1_k127_5849793_27 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1e-237 737.0
HKD1_k127_5849793_28 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 4.965e-235 729.0
HKD1_k127_5849793_29 Belongs to the UPF0348 family - - - 7.206e-233 725.0
HKD1_k127_5849793_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1581.0
HKD1_k127_5849793_30 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 1.086e-231 719.0
HKD1_k127_5849793_31 Permease family K02824 - - 7.033e-226 704.0
HKD1_k127_5849793_32 Component of the transport system for branched-chain amino acids K03311 - - 1.453e-225 704.0
HKD1_k127_5849793_33 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 1.009e-221 691.0
HKD1_k127_5849793_34 Thiamine pyrophosphokinase C terminal - - - 1.057e-219 683.0
HKD1_k127_5849793_35 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 1.794e-219 682.0
HKD1_k127_5849793_36 Psort location Cytoplasmic, score K07478 - - 1.784e-218 683.0
HKD1_k127_5849793_37 Protein of unknown function (DUF3866) - - - 9.899e-212 660.0
HKD1_k127_5849793_38 Radical SAM - - - 6.752e-211 657.0
HKD1_k127_5849793_39 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 1.496e-206 643.0
HKD1_k127_5849793_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1502.0
HKD1_k127_5849793_40 Sporulation integral membrane protein YlbJ - - - 3.109e-205 644.0
HKD1_k127_5849793_41 Stage III sporulation protein AE (spore_III_AE) K06394 - - 9.726e-202 633.0
HKD1_k127_5849793_42 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 1.115e-200 627.0
HKD1_k127_5849793_43 dehydrogenase (FMN-dependent) - - - 2.59e-196 616.0
HKD1_k127_5849793_44 DNA protecting protein DprA K04096 - - 4.409e-195 612.0
HKD1_k127_5849793_45 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 594.0
HKD1_k127_5849793_46 ATPases associated with a variety of cellular activities K06390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 591.0
HKD1_k127_5849793_47 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 597.0
HKD1_k127_5849793_48 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 586.0
HKD1_k127_5849793_49 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 584.0
HKD1_k127_5849793_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1270.0
HKD1_k127_5849793_50 enoyl- acyl-carrier-protein reductase II K02371 - 1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 571.0
HKD1_k127_5849793_51 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 567.0
HKD1_k127_5849793_52 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 567.0
HKD1_k127_5849793_53 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 573.0
HKD1_k127_5849793_54 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 556.0
HKD1_k127_5849793_55 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 556.0
HKD1_k127_5849793_56 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process K07699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 546.0
HKD1_k127_5849793_57 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 547.0
HKD1_k127_5849793_58 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 540.0
HKD1_k127_5849793_59 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 537.0
HKD1_k127_5849793_6 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1250.0
HKD1_k127_5849793_60 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 543.0
HKD1_k127_5849793_61 2-hydroxyglutaryl-CoA dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 537.0
HKD1_k127_5849793_62 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 535.0
HKD1_k127_5849793_63 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 530.0
HKD1_k127_5849793_64 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 525.0
HKD1_k127_5849793_65 Peptidase, U32 family K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 525.0
HKD1_k127_5849793_66 SpoIVB peptidase S55 K06399 - 3.4.21.116 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 526.0
HKD1_k127_5849793_67 Ribosomal RNA large subunit methyltransferase J K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 510.0
HKD1_k127_5849793_68 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 511.0
HKD1_k127_5849793_69 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 508.0
HKD1_k127_5849793_7 arylsulfatase activity - - - 0.0 1168.0
HKD1_k127_5849793_70 Glycoprotease family K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 508.0
HKD1_k127_5849793_71 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 509.0
HKD1_k127_5849793_72 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 503.0
HKD1_k127_5849793_73 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009885 503.0
HKD1_k127_5849793_74 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 491.0
HKD1_k127_5849793_75 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 491.0
HKD1_k127_5849793_76 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 482.0
HKD1_k127_5849793_77 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 476.0
HKD1_k127_5849793_78 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 467.0
HKD1_k127_5849793_79 S4 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 456.0
HKD1_k127_5849793_8 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1131.0
HKD1_k127_5849793_80 3-oxoacyl- acyl-carrier-protein reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 454.0
HKD1_k127_5849793_81 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor K03706 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 454.0
HKD1_k127_5849793_82 Copper transport outer membrane protein, MctB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 444.0
HKD1_k127_5849793_83 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 434.0
HKD1_k127_5849793_84 phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 430.0
HKD1_k127_5849793_85 Glycosyltransferase, group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 427.0
HKD1_k127_5849793_86 CoA-substrate-specific enzyme activase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 429.0
HKD1_k127_5849793_87 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 424.0
HKD1_k127_5849793_88 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 419.0
HKD1_k127_5849793_89 GNAT acetyltransferase K06976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 420.0
HKD1_k127_5849793_9 PAS domain - - - 0.0 1070.0
HKD1_k127_5849793_90 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 413.0
HKD1_k127_5849793_91 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 409.0
HKD1_k127_5849793_92 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 407.0
HKD1_k127_5849793_93 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 402.0
HKD1_k127_5849793_94 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 396.0
HKD1_k127_5849793_95 zinc metallopeptidase K06973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 395.0
HKD1_k127_5849793_96 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 393.0
HKD1_k127_5849793_97 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 394.0
HKD1_k127_5849793_98 Cytidine monophosphokinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 388.0
HKD1_k127_5849793_99 FCD K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 389.0
HKD1_k127_5875391_0 Diguanylate cyclase - - - 1.617e-230 734.0
HKD1_k127_5875391_1 Nucleoside H+ symporter K05820 - - 2.919e-218 682.0
HKD1_k127_5875391_10 Cupin superfamily (DUF985) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 307.0
HKD1_k127_5875391_11 cysteine-type peptidase activity K01447,K21471 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 296.0
HKD1_k127_5875391_12 acetyltransferase, GNAT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002345 279.0
HKD1_k127_5875391_13 Integral membrane protein (intg_mem_TP0381) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003237 281.0
HKD1_k127_5875391_14 transcriptional regulatory protein K02475,K11615,K11692,K11712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000251 260.0
HKD1_k127_5875391_15 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009949 252.0
HKD1_k127_5875391_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002917 246.0
HKD1_k127_5875391_17 BFD-like [2Fe-2S] binding domain K02192 - - 0.0000000000000000188 84.0
HKD1_k127_5875391_18 Belongs to the glycosyl hydrolase 1 family K01223 - 3.2.1.86 0.0000000000000001943 79.0
HKD1_k127_5875391_19 GyrI-like small molecule binding domain - - - 0.0000000000000005846 79.0
HKD1_k127_5875391_2 Ammonium Transporter K06580 - - 3.387e-200 630.0
HKD1_k127_5875391_21 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000006051 59.0
HKD1_k127_5875391_22 Ribosomal protein L7/L12 C-terminal domain - - - 0.000000006939 58.0
HKD1_k127_5875391_23 Sugar (and other) transporter - - - 0.0000008969 51.0
HKD1_k127_5875391_24 Pyruvate formate lyase-like K20038 - 4.3.99.4 0.000001602 51.0
HKD1_k127_5875391_25 Nucleoside H+ symporter K05820 - - 0.000002725 49.0
HKD1_k127_5875391_26 InsA N-terminal domain - - - 0.000003356 49.0
HKD1_k127_5875391_27 Pyruvate formate lyase-like K00656,K20038 - 2.3.1.54,4.3.99.4 0.00004098 46.0
HKD1_k127_5875391_3 Glycosyl hydrolase-like 10 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 590.0
HKD1_k127_5875391_4 Phospholipase, patatin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 516.0
HKD1_k127_5875391_5 CHASE4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 547.0
HKD1_k127_5875391_6 Competence protein ComEC K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 431.0
HKD1_k127_5875391_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 409.0
HKD1_k127_5875391_8 Psort location Cytoplasmic, score - GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005506,GO:0006091,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009266,GO:0009268,GO:0009408,GO:0009409,GO:0009628,GO:0009636,GO:0009651,GO:0009987,GO:0010035,GO:0010446,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0016999,GO:0017001,GO:0017144,GO:0022900,GO:0033554,GO:0034599,GO:0034605,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070417,GO:0070482,GO:0070887,GO:0071214,GO:0071236,GO:0071453,GO:0071467,GO:0071469,GO:0071470,GO:0071472,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:0104004,GO:1901700,GO:1901701,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 349.0
HKD1_k127_5875391_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 310.0
HKD1_k127_5878006_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1166.0
HKD1_k127_5878006_1 Molydopterin dinucleotide binding domain K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 3.795e-317 975.0
HKD1_k127_5878006_10 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system K02071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 535.0
HKD1_k127_5878006_11 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 475.0
HKD1_k127_5878006_12 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 438.0
HKD1_k127_5878006_13 Belongs to the nlpA lipoprotein family K02073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 401.0
HKD1_k127_5878006_14 Helix-turn-helix domain K07219 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 392.0
HKD1_k127_5878006_15 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 383.0
HKD1_k127_5878006_16 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 366.0
HKD1_k127_5878006_17 Molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 373.0
HKD1_k127_5878006_18 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 339.0
HKD1_k127_5878006_19 ABC transporter permease K02072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 326.0
HKD1_k127_5878006_2 DNA binding domain, excisionase family K03750,K07219 - 2.10.1.1 4.984e-218 693.0
HKD1_k127_5878006_20 Type I restriction enzyme R protein N terminus (HSDR_N) K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 315.0
HKD1_k127_5878006_21 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 297.0
HKD1_k127_5878006_22 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 297.0
HKD1_k127_5878006_23 FdhD/NarQ family K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 291.0
HKD1_k127_5878006_24 Protein of unknown function (DUF3793) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008315 250.0
HKD1_k127_5878006_25 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000001261 237.0
HKD1_k127_5878006_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000004547 216.0
HKD1_k127_5878006_27 inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000082 179.0
HKD1_k127_5878006_28 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000000004529 138.0
HKD1_k127_5878006_29 lipid binding - - - 0.000000000000000000000000000000001576 130.0
HKD1_k127_5878006_3 Molybdopterin oxidoreductase, Fe4S4 K00123,K22341 - 1.17.1.11,1.17.1.9 1.404e-212 662.0
HKD1_k127_5878006_30 PFAM ABC transporter related K06857 - 3.6.3.55 0.00000000000000000000000000003423 125.0
HKD1_k127_5878006_32 - - - - 0.00000000000000000003825 90.0
HKD1_k127_5878006_4 Sulfate permease family K03321 - - 2.255e-200 631.0
HKD1_k127_5878006_5 L-aspartate oxidase K00278 - 1.4.3.16 3.027e-194 614.0
HKD1_k127_5878006_6 VanW like protein K18346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 593.0
HKD1_k127_5878006_7 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 571.0
HKD1_k127_5878006_8 Protein of unknown function (DUF1002) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 561.0
HKD1_k127_5878006_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 544.0
HKD1_k127_5924886_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1066.0
HKD1_k127_5924886_1 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 346.0
HKD1_k127_5924886_2 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 361.0
HKD1_k127_5924886_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 274.0
HKD1_k127_5924886_4 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002073 231.0
HKD1_k127_6097753_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1447.0
HKD1_k127_6097753_1 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 1.176e-212 665.0
HKD1_k127_6097753_10 Phosphate acetyl/butaryl transferase K00634 - 2.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 354.0
HKD1_k127_6097753_11 B3/4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 298.0
HKD1_k127_6097753_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000007207 219.0
HKD1_k127_6097753_13 - - - - 0.00000000000000000000000000000000000000004859 154.0
HKD1_k127_6097753_14 NADH ubiquinone oxidoreductase 24 kD subunit - - - 0.0000000000000000000000000000484 117.0
HKD1_k127_6097753_15 - - - - 0.0000000000000000000000000002344 114.0
HKD1_k127_6097753_16 - - - - 0.0000000000000000006871 88.0
HKD1_k127_6097753_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 9.372e-207 657.0
HKD1_k127_6097753_3 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K03317 - - 4.483e-201 632.0
HKD1_k127_6097753_4 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 591.0
HKD1_k127_6097753_5 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 589.0
HKD1_k127_6097753_6 Aldehyde dehydrogenase family K13922,K18119 - 1.2.1.76,1.2.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 577.0
HKD1_k127_6097753_7 Belongs to the acetokinase family K00929 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761 2.7.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 463.0
HKD1_k127_6097753_8 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 449.0
HKD1_k127_6097753_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 357.0
HKD1_k127_6184409_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 561.0
HKD1_k127_619907_0 malic enzyme K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 427.0
HKD1_k127_619907_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 382.0
HKD1_k127_619907_10 PFAM NADPH-dependent FMN reductase - - - 0.00000000889 58.0
HKD1_k127_619907_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000002871 172.0
HKD1_k127_619907_3 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000006718 165.0
HKD1_k127_619907_4 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000249 164.0
HKD1_k127_619907_5 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000006967 143.0
HKD1_k127_619907_6 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000008431 116.0
HKD1_k127_619907_8 Protein of unknown function (DUF421) - - - 0.00000000000001423 75.0
HKD1_k127_619907_9 GNAT family K03790 - 2.3.1.128 0.000000000008294 65.0
HKD1_k127_6261642_0 DnaB-like helicase N terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 290.0
HKD1_k127_6261642_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001068 264.0
HKD1_k127_6261642_2 Mor transcription activator family - - - 0.000000000000000000000000000000000002252 139.0
HKD1_k127_6261642_3 sequence-specific DNA binding - - - 0.0000000000000000000000000002189 115.0
HKD1_k127_6261642_4 Protein of unknown function (DUF1659) - - - 0.000000000000000000000007657 102.0
HKD1_k127_6261642_5 Protein of unknown function (DUF2922) - - - 0.0000000000000000000006325 96.0
HKD1_k127_6261642_6 YvrJ protein family - - - 0.00000000000000004403 81.0
HKD1_k127_6261642_7 - - - - 0.000000000008715 65.0
HKD1_k127_6261642_8 PFAM transposase, mutator K07493 - - 0.0003445 50.0
HKD1_k127_6379909_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 2047.0
HKD1_k127_6379909_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1449.0
HKD1_k127_6379909_10 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 8.223e-270 832.0
HKD1_k127_6379909_11 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 2.905e-265 822.0
HKD1_k127_6379909_12 Psort location Cytoplasmic, score K19689 - - 4.031e-253 782.0
HKD1_k127_6379909_13 COG COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 1.304e-246 764.0
HKD1_k127_6379909_14 Cys/Met metabolism PLP-dependent enzyme K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 8.852e-234 726.0
HKD1_k127_6379909_15 Amidinotransferase K01478 - 3.5.3.6 1.751e-232 723.0
HKD1_k127_6379909_16 Helix-turn-helix XRE-family like proteins - - - 2.279e-225 704.0
HKD1_k127_6379909_17 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 6.653e-224 696.0
HKD1_k127_6379909_18 Carbamoyl-phosphate synthetase glutamine chain K01956 - 6.3.5.5 3.836e-222 689.0
HKD1_k127_6379909_19 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 3.756e-219 682.0
HKD1_k127_6379909_2 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0 1334.0
HKD1_k127_6379909_20 Replication initiation and membrane attachment - - - 8.162e-206 642.0
HKD1_k127_6379909_21 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611 - 2.1.3.3 3.297e-202 631.0
HKD1_k127_6379909_22 pfkB family carbohydrate kinase K00852,K16328 - 2.7.1.15,2.7.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 601.0
HKD1_k127_6379909_23 DNA replication protein DnaC K02315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 579.0
HKD1_k127_6379909_24 RmlD substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 574.0
HKD1_k127_6379909_25 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 568.0
HKD1_k127_6379909_26 Metallo-beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 512.0
HKD1_k127_6379909_27 cysteine desulfurase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 510.0
HKD1_k127_6379909_28 AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 500.0
HKD1_k127_6379909_29 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 487.0
HKD1_k127_6379909_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1203.0
HKD1_k127_6379909_30 sporulation initiation inhibitor protein Soj K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 473.0
HKD1_k127_6379909_31 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 473.0
HKD1_k127_6379909_32 Psort location Cytoplasmic, score K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 456.0
HKD1_k127_6379909_33 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 441.0
HKD1_k127_6379909_34 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 434.0
HKD1_k127_6379909_35 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 431.0
HKD1_k127_6379909_36 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 428.0
HKD1_k127_6379909_37 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 422.0
HKD1_k127_6379909_38 Membrane protein insertase, YidC Oxa1 family K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 398.0
HKD1_k127_6379909_39 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 398.0
HKD1_k127_6379909_4 DHHA1 domain protein - - - 0.0 1178.0
HKD1_k127_6379909_40 4Fe-4S binding domain K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 392.0
HKD1_k127_6379909_41 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 380.0
HKD1_k127_6379909_42 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 342.0
HKD1_k127_6379909_43 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 329.0
HKD1_k127_6379909_44 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 306.0
HKD1_k127_6379909_45 Single-stranded DNA-binding protein K03111 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 304.0
HKD1_k127_6379909_46 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 321.0
HKD1_k127_6379909_47 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 298.0
HKD1_k127_6379909_48 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 292.0
HKD1_k127_6379909_49 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001339 255.0
HKD1_k127_6379909_5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1172.0
HKD1_k127_6379909_50 PhnA Zinc-Ribbon K06193 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007506 240.0
HKD1_k127_6379909_51 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004498 238.0
HKD1_k127_6379909_52 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001166 233.0
HKD1_k127_6379909_53 cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000003341 211.0
HKD1_k127_6379909_54 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000003106 211.0
HKD1_k127_6379909_55 MazG-like family - - - 0.000000000000000000000000000000000000000000000000000000006122 199.0
HKD1_k127_6379909_56 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000000000000000000000000000000007594 200.0
HKD1_k127_6379909_57 Vitamin B12 dependent methionine synthase, activation domain K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000003616 190.0
HKD1_k127_6379909_58 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000004702 181.0
HKD1_k127_6379909_59 STAS domain K04749 - - 0.000000000000000000000000000000000000000000000000008036 181.0
HKD1_k127_6379909_6 Peptidase family M1 domain - - - 4.982e-274 849.0
HKD1_k127_6379909_60 - - - - 0.0000000000000000000000000000000000000000000000002627 180.0
HKD1_k127_6379909_61 Putative inner membrane exporter, YdcZ K09936 - - 0.00000000000000000000000000000000000000000000005759 174.0
HKD1_k127_6379909_62 Putative inner membrane exporter, YdcZ K09936 - - 0.00000000000000000000000000000000000000000000405 168.0
HKD1_k127_6379909_63 YtxH-like protein - - - 0.00000000000000000000000000000000000000000001748 163.0
HKD1_k127_6379909_64 R3H domain protein K06346 - - 0.0000000000000000000000000000000000000000000209 168.0
HKD1_k127_6379909_65 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000000000000000028 153.0
HKD1_k127_6379909_66 Protein of unknown function (DUF3343) - - - 0.00000000000000000000000000000000000000006253 152.0
HKD1_k127_6379909_67 domain, Protein K05349 - 3.2.1.21 0.0000000000000000000000000000000000000006108 168.0
HKD1_k127_6379909_68 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000002386 154.0
HKD1_k127_6379909_69 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000001491 144.0
HKD1_k127_6379909_7 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 5.383e-274 844.0
HKD1_k127_6379909_70 - - - - 0.0000000000000000000000000000000000005091 142.0
HKD1_k127_6379909_71 competence protein COMEC - - - 0.00000000000000000000000000000000000137 157.0
HKD1_k127_6379909_72 - - - - 0.000000000000000000000000000000000001603 139.0
HKD1_k127_6379909_73 Protein of unknown function (DUF1653) - - - 0.00000000000000000000000000000001221 127.0
HKD1_k127_6379909_74 S4 domain K14761 - - 0.0000000000000000000000000000006603 122.0
HKD1_k127_6379909_75 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000000000000001732 114.0
HKD1_k127_6379909_76 - - - - 0.000000000000000000000007359 104.0
HKD1_k127_6379909_78 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000006388 80.0
HKD1_k127_6379909_79 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 - 4.4.1.21 0.00000000000000009257 79.0
HKD1_k127_6379909_8 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 3.484e-273 843.0
HKD1_k127_6379909_80 - - - - 0.0000000000007961 68.0
HKD1_k127_6379909_81 NlpC/P60 family - - - 0.000000005303 58.0
HKD1_k127_6379909_9 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 5.28e-272 838.0
HKD1_k127_6395499_0 Ethanolamine ammonia lyase large subunit (EutB) K03735 - 4.3.1.7 9.33e-297 910.0
HKD1_k127_6395499_1 Ethanolamine utilisation protein EutA K04019 - - 5.22e-287 884.0
HKD1_k127_6395499_10 VanW like protein K18346 - - 3.066e-194 612.0
HKD1_k127_6395499_11 Ethanolamine ammonia-lyase light chain (EutC) K03736 - 4.3.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 569.0
HKD1_k127_6395499_12 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 539.0
HKD1_k127_6395499_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 501.0
HKD1_k127_6395499_14 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 494.0
HKD1_k127_6395499_15 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 473.0
HKD1_k127_6395499_16 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 464.0
HKD1_k127_6395499_17 Predicted membrane protein (DUF2232) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 458.0
HKD1_k127_6395499_18 BMC K04026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 414.0
HKD1_k127_6395499_19 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 402.0
HKD1_k127_6395499_2 Histidine kinase K00936 - 2.7.13.3 1.001e-278 860.0
HKD1_k127_6395499_20 ABC transporter, ATP-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 392.0
HKD1_k127_6395499_21 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 389.0
HKD1_k127_6395499_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 372.0
HKD1_k127_6395499_23 ANTAR K22010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 372.0
HKD1_k127_6395499_24 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 361.0
HKD1_k127_6395499_25 Psort location Cytoplasmic, score - GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005506,GO:0006091,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009266,GO:0009268,GO:0009408,GO:0009409,GO:0009628,GO:0009636,GO:0009651,GO:0009987,GO:0010035,GO:0010446,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0016999,GO:0017001,GO:0017144,GO:0022900,GO:0033554,GO:0034599,GO:0034605,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070417,GO:0070482,GO:0070887,GO:0071214,GO:0071236,GO:0071453,GO:0071467,GO:0071469,GO:0071470,GO:0071472,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:0104004,GO:1901700,GO:1901701,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 350.0
HKD1_k127_6395499_26 SurA N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 320.0
HKD1_k127_6395499_27 Glycerophosphoryl diester phosphodiesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 296.0
HKD1_k127_6395499_28 Ethanolamine utilisation - propanediol utilisation K04029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 289.0
HKD1_k127_6395499_29 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004166 265.0
HKD1_k127_6395499_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 1.045e-239 745.0
HKD1_k127_6395499_30 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000848 258.0
HKD1_k127_6395499_31 BMC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008556 244.0
HKD1_k127_6395499_32 PFAM microcompartments protein K04031 - - 0.000000000000000000000000000000000000000000000000000000000000002016 218.0
HKD1_k127_6395499_33 WLM domain K07043 - - 0.0000000000000000000000000000000000000000000000000000000000005827 218.0
HKD1_k127_6395499_34 - - - - 0.0000000000000000000000000000000000000000000000000000001642 203.0
HKD1_k127_6395499_35 Domain of unknown function (DUF4870) K09940 - - 0.00000000000000000000000000000000000000000000965 165.0
HKD1_k127_6395499_37 Dynamin family - - - 0.00000000000000000000000000000000000000000002395 164.0
HKD1_k127_6395499_38 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000002162 161.0
HKD1_k127_6395499_39 Peptidase dimerisation domain K02083 - 3.5.3.9 0.00000000000000000000000000000006393 126.0
HKD1_k127_6395499_4 ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - 2.898e-235 739.0
HKD1_k127_6395499_40 - - - - 0.000000000000000000000001883 104.0
HKD1_k127_6395499_41 Thioredoxin - - - 0.0000000000000000003724 94.0
HKD1_k127_6395499_43 - - - - 0.00000000000000004017 85.0
HKD1_k127_6395499_44 Ferrous iron transport protein B K04759 - - 0.000001204 51.0
HKD1_k127_6395499_45 Threonine aldolase K01620 - 4.1.2.48 0.000008278 48.0
HKD1_k127_6395499_46 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928,K14392 - - 0.00004633 46.0
HKD1_k127_6395499_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 5.199e-235 729.0
HKD1_k127_6395499_6 Psort location CytoplasmicMembrane, score 10.00 K03294 - - 7.766e-231 720.0
HKD1_k127_6395499_7 Iron-containing alcohol dehydrogenase - - - 1.151e-212 663.0
HKD1_k127_6395499_8 Domain of unknown function (DUF362) - - - 1.95e-204 640.0
HKD1_k127_6395499_9 Efflux ABC transporter, permease protein K02004 - - 4.106e-201 632.0
HKD1_k127_6490037_0 Peptidase, U32 family K08303 - - 3.407e-242 751.0
HKD1_k127_6490037_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 2.225e-232 724.0
HKD1_k127_6490037_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.533e-224 702.0
HKD1_k127_6490037_3 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 295.0
HKD1_k127_6527482_0 DNA helicase K03657 - 3.6.4.12 0.0 1374.0
HKD1_k127_6527482_1 von Willebrand factor (vWF) type A domain - - - 1.527e-275 857.0
HKD1_k127_6527482_2 M18 family aminopeptidase K01267 - 3.4.11.21 2.639e-257 796.0
HKD1_k127_6527482_3 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 522.0
HKD1_k127_6527482_4 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 496.0
HKD1_k127_6527482_5 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 415.0
HKD1_k127_6527482_6 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 407.0
HKD1_k127_6527482_7 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 368.0
HKD1_k127_6527482_8 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002796 253.0
HKD1_k127_6527482_9 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02009 - - 0.00000000000000000000000000001415 119.0
HKD1_k127_6612921_0 Bacterial SNF2 helicase associated K08282 - 2.7.11.1 0.0 1838.0
HKD1_k127_6612921_1 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K17898 - 5.4.3.5 0.0 1441.0
HKD1_k127_6612921_10 PAS fold - - - 4.175e-271 847.0
HKD1_k127_6612921_11 Bacterial regulatory protein, Fis family K06714 - - 9.272e-266 822.0
HKD1_k127_6612921_12 DbpA RNA binding domain K05592 - 3.6.4.13 1.107e-258 803.0
HKD1_k127_6612921_13 argininosuccinate lyase K01755 - 4.3.2.1 1.512e-256 794.0
HKD1_k127_6612921_14 Extracellular solute-binding protein K10117 - - 2.957e-250 775.0
HKD1_k127_6612921_15 His Kinase A (phosphoacceptor) domain - - - 3.628e-239 751.0
HKD1_k127_6612921_16 Subtilase family - - - 1.763e-225 711.0
HKD1_k127_6612921_17 dihydrodipicolinate reductase K21672 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047530,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.4.1.12,1.4.1.26 6.687e-215 669.0
HKD1_k127_6612921_18 Na+/H+ antiporter family K03315 - - 2.84e-213 671.0
HKD1_k127_6612921_19 Transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 575.0
HKD1_k127_6612921_2 Glycosyl hydrolase family 65 central catalytic domain protein K00691 - 2.4.1.8 0.0 1326.0
HKD1_k127_6612921_20 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 569.0
HKD1_k127_6612921_21 UV-endonuclease UvdE K13281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 525.0
HKD1_k127_6612921_22 Fusaric acid resistance protein-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 529.0
HKD1_k127_6612921_23 PFAM Binding-protein-dependent transport system inner membrane component K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 503.0
HKD1_k127_6612921_24 ABC transporter permease K10119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 466.0
HKD1_k127_6612921_25 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 453.0
HKD1_k127_6612921_26 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 437.0
HKD1_k127_6612921_27 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 437.0
HKD1_k127_6612921_28 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005914 436.0
HKD1_k127_6612921_29 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 431.0
HKD1_k127_6612921_3 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O - - - 0.0 1063.0
HKD1_k127_6612921_30 Rossmann fold nucleotide-binding protein involved in DNA uptake - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 424.0
HKD1_k127_6612921_31 Alanine racemase, N-terminal domain K21898 - 5.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 424.0
HKD1_k127_6612921_32 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 401.0
HKD1_k127_6612921_33 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 378.0
HKD1_k127_6612921_34 Hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 372.0
HKD1_k127_6612921_35 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 343.0
HKD1_k127_6612921_36 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 324.0
HKD1_k127_6612921_37 Haloacid dehalogenase-like hydrolase K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 324.0
HKD1_k127_6612921_38 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 293.0
HKD1_k127_6612921_39 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 291.0
HKD1_k127_6612921_4 Alpha-amylase domain K01176,K01182,K01215 - 3.2.1.1,3.2.1.10,3.2.1.70 1.9e-322 990.0
HKD1_k127_6612921_40 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008636 274.0
HKD1_k127_6612921_41 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003513 282.0
HKD1_k127_6612921_43 - - - - 0.000000000000000000000000000000000000000000000000000001393 201.0
HKD1_k127_6612921_44 - K21399 GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 2.3.1.263 0.00000000000000000000000000000000000000000000000000000424 191.0
HKD1_k127_6612921_45 helix_turn_helix gluconate operon transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000004466 177.0
HKD1_k127_6612921_46 D-ornithine 4,5-aminomutase alpha-subunit K17899 - 5.4.3.5 0.00000000000000000000000000000000000000000002998 164.0
HKD1_k127_6612921_47 3D domain - - - 0.000000000000000000000000000000000000001035 152.0
HKD1_k127_6612921_48 hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000001504 141.0
HKD1_k127_6612921_49 Transcriptional Coactivator p15 (PC4) - - - 0.000000000000000000000000000000001266 130.0
HKD1_k127_6612921_5 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 1.353e-294 905.0
HKD1_k127_6612921_50 PFAM cytochrome - - - 0.0000000000000000000000000002719 118.0
HKD1_k127_6612921_51 Domain of unknown function (DUF3787) - - - 0.000000000000000000000000001016 113.0
HKD1_k127_6612921_52 Ferredoxin K05337 - - 0.000000000000000000000000002051 111.0
HKD1_k127_6612921_6 Pyridoxal-phosphate dependent enzyme K21400 - 2.3.1.263 5.723e-283 872.0
HKD1_k127_6612921_7 Subtilase family - - - 6.624e-278 872.0
HKD1_k127_6612921_8 MutL protein - - - 1.943e-273 844.0
HKD1_k127_6612921_9 Polysaccharide biosynthesis protein K06409 - - 3.604e-273 847.0
HKD1_k127_6622237_0 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0 2195.0
HKD1_k127_6622237_1 stage V sporulation protein K K06413 - - 0.0 1602.0
HKD1_k127_6622237_10 Anion-transporting ATPase K01551 - 3.6.3.16 0.0 1113.0
HKD1_k127_6622237_100 Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 284.0
HKD1_k127_6622237_101 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 281.0
HKD1_k127_6622237_102 IclR helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003251 274.0
HKD1_k127_6622237_103 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005362 287.0
HKD1_k127_6622237_104 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003436 270.0
HKD1_k127_6622237_105 rubredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001546 267.0
HKD1_k127_6622237_106 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003198 274.0
HKD1_k127_6622237_107 Removes the formyl group from the N-terminal Met of newly synthesized proteins K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000001244 249.0
HKD1_k127_6622237_108 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007906 244.0
HKD1_k127_6622237_109 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001565 250.0
HKD1_k127_6622237_11 ABC transporter transmembrane region K06147 - - 0.0 1077.0
HKD1_k127_6622237_110 YcxB-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000123 240.0
HKD1_k127_6622237_111 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000000000000000000000000000000000000000000000000000000000000000000009471 246.0
HKD1_k127_6622237_112 Transcriptional regulator, Crp Fnr family( K21562 - - 0.00000000000000000000000000000000000000000000000000000000000000000002131 239.0
HKD1_k127_6622237_113 Putative Fe-S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000003148 236.0
HKD1_k127_6622237_114 PFAM MaoC domain protein dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000001455 231.0
HKD1_k127_6622237_115 CAAX amino terminal protease family - - - 0.000000000000000000000000000000000000000000000000000000000000000004375 232.0
HKD1_k127_6622237_116 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000000000000000000000000000000000000102 218.0
HKD1_k127_6622237_117 YcxB-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000001864 218.0
HKD1_k127_6622237_118 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000008086 215.0
HKD1_k127_6622237_119 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000002653 222.0
HKD1_k127_6622237_12 His Kinase A (phosphoacceptor) domain - - - 0.0 1022.0
HKD1_k127_6622237_120 Protein of unknown function (DUF2089) - - - 0.00000000000000000000000000000000000000000000000000000000000188 211.0
HKD1_k127_6622237_121 Protein of unknown function (DUF2812) - - - 0.000000000000000000000000000000000000000000000000000000000003875 214.0
HKD1_k127_6622237_122 - - - - 0.000000000000000000000000000000000000000000000000000000000004958 212.0
HKD1_k127_6622237_123 - - - - 0.0000000000000000000000000000000000000000000000000000000001394 206.0
HKD1_k127_6622237_124 PucR C-terminal helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000007373 213.0
HKD1_k127_6622237_125 Arsenical resistance operon trans-acting repressor ArsD - - - 0.0000000000000000000000000000000000000000000000000000001103 196.0
HKD1_k127_6622237_126 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000172 204.0
HKD1_k127_6622237_127 - - - - 0.0000000000000000000000000000000000000000000000000000003574 214.0
HKD1_k127_6622237_128 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000003005 220.0
HKD1_k127_6622237_129 - - - - 0.000000000000000000000000000000000000000000000000000005375 191.0
HKD1_k127_6622237_13 Cache 3/Cache 2 fusion domain - - - 0.0 1013.0
HKD1_k127_6622237_130 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000002034 192.0
HKD1_k127_6622237_131 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000000000000000001117 185.0
HKD1_k127_6622237_132 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000001586 184.0
HKD1_k127_6622237_133 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000000000004505 180.0
HKD1_k127_6622237_134 Transcriptional regulator, HxlR family - - - 0.00000000000000000000000000000000000000000000000007029 179.0
HKD1_k127_6622237_135 belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000001864 172.0
HKD1_k127_6622237_136 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000002613 168.0
HKD1_k127_6622237_137 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000001342 168.0
HKD1_k127_6622237_138 - - - - 0.00000000000000000000000000000000000000000001911 165.0
HKD1_k127_6622237_139 - - - - 0.0000000000000000000000000000000000000000000319 162.0
HKD1_k127_6622237_14 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 1.914e-314 969.0
HKD1_k127_6622237_140 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000002051 159.0
HKD1_k127_6622237_142 - - - - 0.00000000000000000000000000000000000000003342 159.0
HKD1_k127_6622237_143 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000003372 148.0
HKD1_k127_6622237_144 Cache 3/Cache 2 fusion domain - - - 0.000000000000000000000000000000000000004203 146.0
HKD1_k127_6622237_145 Nitroreductase family - - - 0.0000000000000000000000000000000000001482 147.0
HKD1_k127_6622237_146 Mor transcription activator family - - - 0.00000000000000000000000000000000001366 136.0
HKD1_k127_6622237_147 Accessory gene regulator B K07813 - - 0.00000000000000000000000000000000006014 140.0
HKD1_k127_6622237_148 PFAM Helix-turn-helix K07729 - - 0.000000000000000000000000000000004363 128.0
HKD1_k127_6622237_149 RDD family - - - 0.00000000000000000000000000000001423 131.0
HKD1_k127_6622237_15 DNA polymerase K02334 - 2.7.7.7 8.559e-312 964.0
HKD1_k127_6622237_150 - - - - 0.0000000000000000000000000000009296 123.0
HKD1_k127_6622237_151 FMN_bind K00244,K17363 - 1.3.5.4,1.3.99.33 0.000000000000000000000000000001669 122.0
HKD1_k127_6622237_152 Helix-turn-helix domain K03892 - - 0.00000000000000000000000000001132 120.0
HKD1_k127_6622237_153 Protein of unknown function (DUF454) K09790 - - 0.0000000000000000000000000001825 120.0
HKD1_k127_6622237_154 - - - - 0.0000000000000000000000000004019 117.0
HKD1_k127_6622237_155 Domain of unknown function (DUF4177) - - - 0.0000000000000000000000000005539 114.0
HKD1_k127_6622237_157 - - - - 0.000000000000000000000000001803 115.0
HKD1_k127_6622237_158 - - - - 0.000000000000000000000000002716 113.0
HKD1_k127_6622237_159 PFAM regulatory protein TetR - - - 0.0000000000000000000000000732 114.0
HKD1_k127_6622237_16 ABC-2 family transporter protein K09696 - - 7.877e-308 955.0
HKD1_k127_6622237_160 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000001542 107.0
HKD1_k127_6622237_161 - - - - 0.0000000000000000000000002017 107.0
HKD1_k127_6622237_163 - - - - 0.0000000000000000000000004693 107.0
HKD1_k127_6622237_164 Protein of unknown function (DUF2922) - - - 0.0000000000000000000000004742 106.0
HKD1_k127_6622237_166 - - - - 0.00000000000000000000000112 115.0
HKD1_k127_6622237_167 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000000000000005982 102.0
HKD1_k127_6622237_168 redox-active disulfide protein 2 - - - 0.00000000000000000000003644 100.0
HKD1_k127_6622237_17 Histidine kinase K07718 - 2.7.13.3 5.184e-301 930.0
HKD1_k127_6622237_170 YvrJ protein family - - - 0.0000000000000000001281 89.0
HKD1_k127_6622237_171 - - - - 0.0000000000000000002502 88.0
HKD1_k127_6622237_172 YvrJ protein family - - - 0.0000000000000000003322 87.0
HKD1_k127_6622237_173 - - - - 0.00000000000000001151 83.0
HKD1_k127_6622237_174 YvrJ protein family - - - 0.00000000000000001235 82.0
HKD1_k127_6622237_175 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000003369 80.0
HKD1_k127_6622237_177 - - - - 0.0000000000000001637 82.0
HKD1_k127_6622237_178 Protein of unknown function (DUF2922) - - - 0.0000000000000002671 78.0
HKD1_k127_6622237_179 Bacterial regulatory proteins, tetR family - - - 0.000000000001305 70.0
HKD1_k127_6622237_18 PAS fold - - - 2.147e-270 844.0
HKD1_k127_6622237_181 Restriction endonuclease K07448 GO:0001101,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009295,GO:0009415,GO:0009628,GO:0009987,GO:0010035,GO:0015666,GO:0016787,GO:0016788,GO:0032067,GO:0034641,GO:0042221,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051599,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901700 - 0.00000000001328 65.0
HKD1_k127_6622237_184 - - - - 0.000001612 50.0
HKD1_k127_6622237_185 Protein of unknown function (DUF2922) - - - 0.00000839 48.0
HKD1_k127_6622237_186 - - - - 0.00004773 53.0
HKD1_k127_6622237_187 AAA domain - - - 0.00006735 46.0
HKD1_k127_6622237_19 Amino acid permease - - - 6.566e-270 837.0
HKD1_k127_6622237_190 - - - - 0.0001461 47.0
HKD1_k127_6622237_191 - - - - 0.0002971 53.0
HKD1_k127_6622237_2 FtsX-like permease family K02004 - - 0.0 1345.0
HKD1_k127_6622237_20 transporter K02445,K07783 - - 1.05e-269 833.0
HKD1_k127_6622237_21 Na Pi-cotransporter II-like protein K03324 - - 2.514e-269 837.0
HKD1_k127_6622237_22 Peptidase family M28 - - - 3.034e-266 824.0
HKD1_k127_6622237_23 metal-dependent phosphohydrolase, HD sub domain - - - 7.202e-261 820.0
HKD1_k127_6622237_24 ABC transporter K06148 - - 5.671e-258 805.0
HKD1_k127_6622237_25 C4-dicarboxylate anaerobic carrier - - - 5.985e-257 801.0
HKD1_k127_6622237_26 pyrimidine-nucleoside phosphorylase K00756 - 2.4.2.2 1.609e-242 753.0
HKD1_k127_6622237_27 permease K03458,K16345 - - 2.891e-236 736.0
HKD1_k127_6622237_28 MatE - - - 1.799e-229 718.0
HKD1_k127_6622237_29 Sodium/hydrogen exchanger family - - - 1.943e-228 711.0
HKD1_k127_6622237_3 virulence-associated E family protein - - - 0.0 1290.0
HKD1_k127_6622237_30 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 2.489e-227 707.0
HKD1_k127_6622237_31 Branched-chain amino acid transport protein K03311 - - 2.731e-225 704.0
HKD1_k127_6622237_32 Voltage gated chloride channel K03281 - - 3.065e-223 697.0
HKD1_k127_6622237_33 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.118e-221 692.0
HKD1_k127_6622237_34 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K03317 - - 1.695e-208 655.0
HKD1_k127_6622237_35 SBF-like CPA transporter family (DUF4137) K03325 - - 3.998e-205 641.0
HKD1_k127_6622237_36 Transmembrane secretion effector - - - 2.682e-204 642.0
HKD1_k127_6622237_37 CotH protein - - - 1.654e-196 629.0
HKD1_k127_6622237_38 alcohol dehydrogenase - - - 4.697e-196 616.0
HKD1_k127_6622237_39 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 599.0
HKD1_k127_6622237_4 Peroxidase K03782 - 1.11.1.21 0.0 1288.0
HKD1_k127_6622237_40 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 561.0
HKD1_k127_6622237_41 FMN_bind K00244,K17363 - 1.3.5.4,1.3.99.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 563.0
HKD1_k127_6622237_42 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 555.0
HKD1_k127_6622237_43 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 546.0
HKD1_k127_6622237_44 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 528.0
HKD1_k127_6622237_45 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 527.0
HKD1_k127_6622237_46 Alpha beta hydrolase K00433,K01055 - 1.11.1.10,3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 511.0
HKD1_k127_6622237_47 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 509.0
HKD1_k127_6622237_48 PHB de-polymerase C-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 507.0
HKD1_k127_6622237_49 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 493.0
HKD1_k127_6622237_5 Psort location Cytoplasmic, score K00656 - 2.3.1.54 0.0 1227.0
HKD1_k127_6622237_50 permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 490.0
HKD1_k127_6622237_51 iron-sulfur cluster-binding protein K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 490.0
HKD1_k127_6622237_52 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 471.0
HKD1_k127_6622237_53 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 458.0
HKD1_k127_6622237_54 domain protein K22230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 452.0
HKD1_k127_6622237_55 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 452.0
HKD1_k127_6622237_56 beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 441.0
HKD1_k127_6622237_57 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 438.0
HKD1_k127_6622237_58 ABC transporter, ATP-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 427.0
HKD1_k127_6622237_59 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 426.0
HKD1_k127_6622237_6 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.0 1213.0
HKD1_k127_6622237_60 Nitroreductase family K19285 - 1.5.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 425.0
HKD1_k127_6622237_61 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 433.0
HKD1_k127_6622237_62 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 417.0
HKD1_k127_6622237_63 ABC transporter K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 410.0
HKD1_k127_6622237_64 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 405.0
HKD1_k127_6622237_65 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 406.0
HKD1_k127_6622237_66 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 400.0
HKD1_k127_6622237_67 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 407.0
HKD1_k127_6622237_68 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 407.0
HKD1_k127_6622237_69 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 394.0
HKD1_k127_6622237_7 AAA domain - - - 0.0 1168.0
HKD1_k127_6622237_70 Cbs domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 397.0
HKD1_k127_6622237_71 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 393.0
HKD1_k127_6622237_72 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 389.0
HKD1_k127_6622237_73 LUD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 382.0
HKD1_k127_6622237_74 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 376.0
HKD1_k127_6622237_75 Belongs to the peptidase S8 family K13275 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 371.0
HKD1_k127_6622237_76 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 366.0
HKD1_k127_6622237_77 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 353.0
HKD1_k127_6622237_78 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 347.0
HKD1_k127_6622237_79 Provides the (R)-glutamate required for cell wall biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 340.0
HKD1_k127_6622237_8 ABC transporter transmembrane region K06147 - - 0.0 1141.0
HKD1_k127_6622237_80 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 341.0
HKD1_k127_6622237_81 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 332.0
HKD1_k127_6622237_82 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 334.0
HKD1_k127_6622237_83 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 328.0
HKD1_k127_6622237_84 SIR2-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 361.0
HKD1_k127_6622237_85 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 321.0
HKD1_k127_6622237_86 Riboflavin biosynthesis protein RibD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 318.0
HKD1_k127_6622237_87 orniTHIne cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 326.0
HKD1_k127_6622237_88 Diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 332.0
HKD1_k127_6622237_89 adenylate kinase (ATP-AMP transphosphorylase) K00939 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 311.0
HKD1_k127_6622237_9 helicase - - - 0.0 1132.0
HKD1_k127_6622237_90 membrane K07149 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 312.0
HKD1_k127_6622237_91 membrane K07149 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 311.0
HKD1_k127_6622237_92 membrane K07149 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 309.0
HKD1_k127_6622237_93 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 311.0
HKD1_k127_6622237_94 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 302.0
HKD1_k127_6622237_95 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 297.0
HKD1_k127_6622237_96 restriction endonuclease K07448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 295.0
HKD1_k127_6622237_97 Domain of unknown function (DUF4179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 304.0
HKD1_k127_6622237_98 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 286.0
HKD1_k127_6622237_99 Protein of unknown function (DUF2815) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 285.0
HKD1_k127_6949018_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.0 1022.0
HKD1_k127_6949018_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 5.637e-313 961.0
HKD1_k127_6949018_10 Protein of unknown function (DUF2804) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 561.0
HKD1_k127_6949018_11 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 554.0
HKD1_k127_6949018_12 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K17722 - 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 531.0
HKD1_k127_6949018_13 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 499.0
HKD1_k127_6949018_14 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006579 479.0
HKD1_k127_6949018_15 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 474.0
HKD1_k127_6949018_16 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 472.0
HKD1_k127_6949018_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 455.0
HKD1_k127_6949018_18 alcohol dehydrogenase K18012 - 1.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 418.0
HKD1_k127_6949018_19 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 411.0
HKD1_k127_6949018_2 Acetyl-CoA hydrolase/transferase N-terminal domain K18118 - 2.8.3.18 2.694e-281 869.0
HKD1_k127_6949018_20 Domain of unknown function (DUF4153) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 414.0
HKD1_k127_6949018_21 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 326.0
HKD1_k127_6949018_22 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004883 273.0
HKD1_k127_6949018_23 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000004159 239.0
HKD1_k127_6949018_24 Thioesterase superfamily K18014 - 4.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000005795 235.0
HKD1_k127_6949018_25 Biotin-requiring enzyme - - - 0.0000000000000000000000000000000000000000000000000000000001038 205.0
HKD1_k127_6949018_26 Oxaloacetate decarboxylase, gamma chain - - - 0.00000000000000000000000000000000000004456 146.0
HKD1_k127_6949018_27 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000000000000003068 138.0
HKD1_k127_6949018_28 BFD-like [2Fe-2S] binding domain - - - 0.000000000000000000973 98.0
HKD1_k127_6949018_29 - - - - 0.000000001501 65.0
HKD1_k127_6949018_3 Predicted Permease Membrane Region K07085 - - 1.935e-246 766.0
HKD1_k127_6949018_4 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 5.682e-226 702.0
HKD1_k127_6949018_5 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 5.886e-222 692.0
HKD1_k127_6949018_6 Metallopeptidase family M24 K01271 - 3.4.13.9 1.339e-210 657.0
HKD1_k127_6949018_7 Reductive dehalogenase subunit - - - 2.946e-208 649.0
HKD1_k127_6949018_8 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 607.0
HKD1_k127_6949018_9 electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 563.0
HKD1_k127_7089480_0 HD domain - - - 6.784e-198 620.0
HKD1_k127_7089480_1 Aldose 1-epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007971 509.0
HKD1_k127_7089480_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 367.0
HKD1_k127_7089480_3 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04068 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 285.0
HKD1_k127_7091751_0 Psort location Cytoplasmic, score - - - 0.0 1588.0
HKD1_k127_7091751_1 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 3.809e-204 649.0
HKD1_k127_7091751_10 Protein of unknown function (DUF2922) - - - 0.00000000000000000000000000000001676 127.0
HKD1_k127_7091751_11 Mor transcription activator family - - - 0.0000000000000000000000000000001169 125.0
HKD1_k127_7091751_12 - - - - 0.0000000000000000000000000000001298 124.0
HKD1_k127_7091751_13 Mor transcription activator family - - - 0.0000000000000000000000000000001604 125.0
HKD1_k127_7091751_14 Protein of unknown function (DUF1659) - - - 0.00000000000000000000000000521 111.0
HKD1_k127_7091751_15 Cro Cl family transcriptional regulator K07729 - - 0.0000000000000000000000001385 109.0
HKD1_k127_7091751_16 Transcriptional - - - 0.00000000000000000000008167 103.0
HKD1_k127_7091751_17 IrrE N-terminal-like domain - - - 0.00000000000000000000008663 104.0
HKD1_k127_7091751_18 YvrJ protein family - - - 0.0000000000000000009532 86.0
HKD1_k127_7091751_19 - - - - 0.0000000000000183 78.0
HKD1_k127_7091751_2 Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 501.0
HKD1_k127_7091751_21 Helix-turn-helix - - - 0.00000004266 58.0
HKD1_k127_7091751_22 Divergent AAA domain protein - - - 0.0000585 47.0
HKD1_k127_7091751_3 Replication initiation and membrane attachment - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 454.0
HKD1_k127_7091751_4 YqaJ viral recombinase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 438.0
HKD1_k127_7091751_5 PFAM IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 340.0
HKD1_k127_7091751_6 N-acetylmuramoyl-L-alanine amidase, peptidoglycan hydrolase, LytC amidase family K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 311.0
HKD1_k127_7091751_7 BRO family, N-terminal domain K07741 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 296.0
HKD1_k127_7091751_8 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000000000000000000000000000009362 185.0
HKD1_k127_7091751_9 - - - - 0.0000000000000000000000000000000000000000000000000803 191.0
HKD1_k127_7123177_0 Cys/Met metabolism PLP-dependent enzyme K00812 - 2.6.1.1 1.678e-254 787.0
HKD1_k127_7123177_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 493.0
HKD1_k127_733101_0 Penicillin-binding protein, transpeptidase domain protein K05515 - 3.4.16.4 0.0 1454.0
HKD1_k127_733101_1 Radical SAM domain protein - - - 0.0 1200.0
HKD1_k127_733101_10 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 382.0
HKD1_k127_733101_11 MGS-like domain K01734 - 4.2.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000009087 254.0
HKD1_k127_733101_12 Rod shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000000000000000000000000000000000000001272 236.0
HKD1_k127_733101_13 RNA-binding protein, YhbY family K07574 - - 0.00000000000000000000000000000000000000000000000000000000000000002793 224.0
HKD1_k127_733101_14 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000000000000000009715 201.0
HKD1_k127_733101_15 Pfam:Peptidase_C108 K07584 - - 0.0000000000000000000000000000000000000000000000000000004675 193.0
HKD1_k127_733101_16 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000000000000000572 181.0
HKD1_k127_733101_17 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.0000000000000000000000000000000000000000000005937 167.0
HKD1_k127_733101_18 Cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000002588 93.0
HKD1_k127_733101_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 1.943e-261 807.0
HKD1_k127_733101_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 1.139e-259 803.0
HKD1_k127_733101_4 S1 RNA binding domain protein K08301 - - 6.533e-246 766.0
HKD1_k127_733101_5 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 2.118e-241 752.0
HKD1_k127_733101_6 Belongs to the SEDS family K05837 - - 2.702e-195 613.0
HKD1_k127_733101_7 Cellulose biosynthesis protein BcsQ K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 482.0
HKD1_k127_733101_8 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 447.0
HKD1_k127_733101_9 Radical SAM-linked protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 390.0
HKD1_k127_7351959_0 Psort location CytoplasmicMembrane, score - - - 1.079e-306 946.0
HKD1_k127_7351959_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 337.0
HKD1_k127_7351959_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000002725 49.0
HKD1_k127_7375560_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0 1141.0
HKD1_k127_7375560_1 Cache 3/Cache 2 fusion domain - - - 1e-323 1000.0
HKD1_k127_7375560_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 520.0
HKD1_k127_7375560_11 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 509.0
HKD1_k127_7375560_12 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 479.0
HKD1_k127_7375560_13 Anion-transporting ATPase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 458.0
HKD1_k127_7375560_14 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 432.0
HKD1_k127_7375560_15 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 451.0
HKD1_k127_7375560_16 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 408.0
HKD1_k127_7375560_17 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 374.0
HKD1_k127_7375560_18 VTC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 370.0
HKD1_k127_7375560_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 336.0
HKD1_k127_7375560_2 Belongs to the UPF0061 (SELO) family - - - 4.585e-275 851.0
HKD1_k127_7375560_20 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 304.0
HKD1_k127_7375560_21 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K15600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 289.0
HKD1_k127_7375560_22 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001497 299.0
HKD1_k127_7375560_23 Domain of unknown function (DUF4956) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000295 267.0
HKD1_k127_7375560_24 MgtC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005437 259.0
HKD1_k127_7375560_25 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002825 258.0
HKD1_k127_7375560_26 Response regulator receiver domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000008337 234.0
HKD1_k127_7375560_27 Response regulator receiver domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001383 215.0
HKD1_k127_7375560_28 - - - - 0.0000000000000000000000000000000000000000000000000000000000000154 220.0
HKD1_k127_7375560_29 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000002411 211.0
HKD1_k127_7375560_3 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 2.434e-251 781.0
HKD1_k127_7375560_30 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000000000000000001649 201.0
HKD1_k127_7375560_31 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000002565 191.0
HKD1_k127_7375560_32 TIGRFAM sporulation peptidase YabG K06436 - - 0.00000000000000000000000000000000000000000000000006643 196.0
HKD1_k127_7375560_33 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000341 166.0
HKD1_k127_7375560_34 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000002714 152.0
HKD1_k127_7375560_35 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000005954 71.0
HKD1_k127_7375560_36 helicase K07464,K10844 - 3.1.12.1,3.6.4.12 0.00000000000302 68.0
HKD1_k127_7375560_37 - - - - 0.0000000000328 64.0
HKD1_k127_7375560_38 - - - - 0.000000009175 56.0
HKD1_k127_7375560_39 Rhodanese Homology Domain - - - 0.0000879 45.0
HKD1_k127_7375560_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.895e-248 768.0
HKD1_k127_7375560_40 DnaB-like helicase N terminal domain - - - 0.0001078 46.0
HKD1_k127_7375560_41 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.000392 44.0
HKD1_k127_7375560_5 Polysaccharide biosynthesis C-terminal domain - - - 6.151e-216 677.0
HKD1_k127_7375560_6 - - - - 4.752e-201 635.0
HKD1_k127_7375560_7 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 559.0
HKD1_k127_7375560_8 Protein of unknown function DUF116 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 558.0
HKD1_k127_7375560_9 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 527.0
HKD1_k127_7427416_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1449.0
HKD1_k127_7427416_1 Aminotransferase K00812,K10907 - 2.6.1.1 1.554e-198 624.0
HKD1_k127_7427416_2 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04068 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 313.0
HKD1_k127_7529494_0 PAS domain - - - 0.0 1137.0
HKD1_k127_7529494_1 Elongation factor SelB, winged helix K03833 - - 0.0 1064.0
HKD1_k127_7529494_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 8.939e-256 793.0
HKD1_k127_7529494_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 575.0
HKD1_k127_7529494_4 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000000000000000000000000000000000000000000001714 226.0
HKD1_k127_7564381_0 Cache 3/Cache 2 fusion domain - - - 1e-323 997.0
HKD1_k127_7564381_1 ABC-type nitrate sulfonate bicarbonate transport K15598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 559.0
HKD1_k127_7564381_10 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000009941 200.0
HKD1_k127_7564381_11 - K21471 - - 0.000000000000000000000000000000000000004362 160.0
HKD1_k127_7564381_12 - K21471 - - 0.00000000000000000000000000000000000001229 160.0
HKD1_k127_7564381_13 Putative cell wall binding repeat 2 - - - 0.0000004618 53.0
HKD1_k127_7564381_2 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 545.0
HKD1_k127_7564381_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 428.0
HKD1_k127_7564381_4 Cell envelope-like function transcriptional attenuator common domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 372.0
HKD1_k127_7564381_5 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 357.0
HKD1_k127_7564381_6 Domain of unknown function (DUF4153) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 321.0
HKD1_k127_7564381_7 HutD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 315.0
HKD1_k127_7564381_8 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K15600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003789 253.0
HKD1_k127_7564381_9 ABC transporter permease K15599 - - 0.00000000000000000000000000000000000000000000000000000000000000002759 231.0
HKD1_k127_7564690_0 Glycosyl transferase family 2 - - - 3.75e-304 948.0
HKD1_k127_7564690_1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - 1.155e-296 919.0
HKD1_k127_7564690_10 PFAM Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 298.0
HKD1_k127_7564690_11 Flagellar hook capping protein - N-terminal region K02389 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009011 267.0
HKD1_k127_7564690_12 Flagellar basal body rod FlgEFG protein C-terminal K02388 - - 0.000000000000000000000000000000000000000000000000000000000000000000001983 236.0
HKD1_k127_7564690_13 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000004703 239.0
HKD1_k127_7564690_14 Flagellar FliJ protein K02413 - - 0.000000000000000000000000000000000000000000000000006016 184.0
HKD1_k127_7564690_15 bacterial-type flagellum organization K02411 - - 0.0000000000000000000000000000000000000000000000008478 184.0
HKD1_k127_7564690_16 - K02418 - - 0.000000000000000000000000000000000000000000000003328 178.0
HKD1_k127_7564690_17 Flagella basal body rod protein K02387 - - 0.00000000000000000000000000000000000000000000004284 171.0
HKD1_k127_7564690_18 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000000000000000003698 128.0
HKD1_k127_7564690_19 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000001977 108.0
HKD1_k127_7564690_2 ATP synthase alpha/beta family, beta-barrel domain K02412,K03224 - 3.6.3.14 5.464e-259 801.0
HKD1_k127_7564690_20 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000003682 48.0
HKD1_k127_7564690_3 The M ring may be actively involved in energy transduction K02409 - - 4.402e-235 736.0
HKD1_k127_7564690_4 FliG C-terminal domain K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 602.0
HKD1_k127_7564690_5 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 593.0
HKD1_k127_7564690_6 Flagellar basal body rod FlgEFG protein C-terminal K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 526.0
HKD1_k127_7564690_7 PFAM Glycosyl transferase family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 473.0
HKD1_k127_7564690_8 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 404.0
HKD1_k127_7564690_9 Flagellar hook-length control protein FliK K02414 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 373.0
HKD1_k127_7621211_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 2066.0
HKD1_k127_7621211_1 Serine/threonine phosphatases, family 2C, catalytic domain K06382 - 3.1.3.16 0.0 1336.0
HKD1_k127_7621211_10 Peptidase family M28 K01258 - 3.4.11.4 8.93e-209 652.0
HKD1_k127_7621211_11 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 2.799e-207 647.0
HKD1_k127_7621211_12 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 9.598e-207 644.0
HKD1_k127_7621211_13 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 4.567e-194 606.0
HKD1_k127_7621211_14 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 578.0
HKD1_k127_7621211_15 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 580.0
HKD1_k127_7621211_16 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 557.0
HKD1_k127_7621211_17 PFAM Type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 569.0
HKD1_k127_7621211_18 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 546.0
HKD1_k127_7621211_19 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 533.0
HKD1_k127_7621211_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1275.0
HKD1_k127_7621211_20 operon repressor K09685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 526.0
HKD1_k127_7621211_21 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 511.0
HKD1_k127_7621211_22 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 507.0
HKD1_k127_7621211_23 SurA N-terminal domain K03769,K07533 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 504.0
HKD1_k127_7621211_24 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 500.0
HKD1_k127_7621211_25 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 494.0
HKD1_k127_7621211_26 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 421.0
HKD1_k127_7621211_27 Pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 430.0
HKD1_k127_7621211_28 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 404.0
HKD1_k127_7621211_29 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 404.0
HKD1_k127_7621211_3 Oligopeptidase F K08602 - - 0.0 1085.0
HKD1_k127_7621211_30 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 393.0
HKD1_k127_7621211_31 thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 379.0
HKD1_k127_7621211_32 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 360.0
HKD1_k127_7621211_33 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step K05985 - 3.1.26.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 336.0
HKD1_k127_7621211_34 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 327.0
HKD1_k127_7621211_35 SpoVT / AbrB like domain K04769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 307.0
HKD1_k127_7621211_36 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 305.0
HKD1_k127_7621211_37 isomerase B K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 302.0
HKD1_k127_7621211_38 Spore cortex protein YabQ (Spore_YabQ) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 280.0
HKD1_k127_7621211_39 cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001472 278.0
HKD1_k127_7621211_4 Stage V sporulation protein B K06409 - - 1.153e-290 898.0
HKD1_k127_7621211_40 carbon utilization K02664 - - 0.000000000000000000000000000000000000000000000000000000000001634 220.0
HKD1_k127_7621211_41 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000000000000000002658 186.0
HKD1_k127_7621211_42 Could be involved in septation K06412 - - 0.000000000000000000000000000000000000000000000000005447 181.0
HKD1_k127_7621211_43 YabP family - - - 0.00000000000000000000000000000000000000005379 153.0
HKD1_k127_7621211_44 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000000008016 139.0
HKD1_k127_7621211_45 S4 domain protein - - - 0.000000000000000000000000000000000001454 139.0
HKD1_k127_7621211_46 Septum formation initiator - - - 0.0000000000000000000000000000000004973 132.0
HKD1_k127_7621211_47 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000002976 116.0
HKD1_k127_7621211_48 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000685 86.0
HKD1_k127_7621211_49 Prokaryotic N-terminal methylation motif K02650 - - 0.000000000003036 78.0
HKD1_k127_7621211_5 Tetrapyrrole methylase K02428,K02499 - 3.6.1.66 3.407e-289 891.0
HKD1_k127_7621211_50 - - - - 0.000000579 61.0
HKD1_k127_7621211_6 Belongs to the MurCDEF family K01924 - 6.3.2.8 6.788e-278 856.0
HKD1_k127_7621211_7 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.182e-277 859.0
HKD1_k127_7621211_8 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 8.507e-272 839.0
HKD1_k127_7621211_9 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 3.187e-213 664.0
HKD1_k127_7850249_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 587.0
HKD1_k127_7850249_1 Transcriptional regulatory protein, C terminal K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 391.0
HKD1_k127_7850249_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 333.0
HKD1_k127_7850249_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 291.0
HKD1_k127_7850249_4 ABC transporter, ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000001201 217.0