Overview

ID MAG01769
Name HKD1_bin.90
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Bacillota
Class Clostridia
Order Tissierellales
Family Sedimentibacteraceae
Genus Sedimentibacter
Species
Assembly information
Completeness (%) 86.96
Contamination (%) 7.18
GC content (%) 30.0
N50 (bp) 2,570
Genome size (bp) 2,522,124

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2830

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_101037_0 S-layer homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 370.0
HKD1_k127_1016258_0 Aminotransferase class I and II K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 4.069e-205 643.0
HKD1_k127_1016258_1 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 561.0
HKD1_k127_1016258_2 - - - - 0.000000000000003831 81.0
HKD1_k127_102091_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 568.0
HKD1_k127_102091_1 Pfam:DUF342 K09749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001476 269.0
HKD1_k127_102091_2 Flagella basal body rod protein K02388,K02391,K02392 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.00000000000000000000000000000000000000000000000000000000000000004352 230.0
HKD1_k127_102091_3 Sigma-70 region 3 K02405 - - 0.0000000000000000000000000000000000000000000000005803 181.0
HKD1_k127_102091_4 Flagellar basal body rod FlgEFG protein C-terminal K02390,K02392 - - 0.00000000000000000000000000000000000000001238 161.0
HKD1_k127_102091_5 RNA polymerase sigma-70 factor, sigma-B F G subfamily K03090,K03091 - - 0.0003688 44.0
HKD1_k127_1031673_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 409.0
HKD1_k127_1038851_0 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000005773 273.0
HKD1_k127_104729_0 ABC transporter K06147 - - 1.734e-207 648.0
HKD1_k127_104729_1 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 337.0
HKD1_k127_104729_2 Abc transporter K06147 - - 0.0000000000000000000000000000000001599 133.0
HKD1_k127_1049112_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 479.0
HKD1_k127_1050533_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000001242 121.0
HKD1_k127_1073735_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 553.0
HKD1_k127_1073735_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001194 259.0
HKD1_k127_1073735_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000003866 83.0
HKD1_k127_1074754_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 608.0
HKD1_k127_1076827_0 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 449.0
HKD1_k127_1076827_1 Protein of unknown function (DUF1444) - - - 0.00000000000000000000000000000000000000000000000378 178.0
HKD1_k127_1077374_0 carboxyltransferase K01571 - 4.1.1.3 1.494e-202 639.0
HKD1_k127_1077374_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000009977 158.0
HKD1_k127_108107_0 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 291.0
HKD1_k127_108107_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000004855 87.0
HKD1_k127_1084789_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 582.0
HKD1_k127_108676_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1026.0
HKD1_k127_108676_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.23e-244 766.0
HKD1_k127_108676_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 521.0
HKD1_k127_108676_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 328.0
HKD1_k127_108676_4 FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000000000000000000000000005406 209.0
HKD1_k127_108676_5 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000008618 187.0
HKD1_k127_108676_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000000000009106 173.0
HKD1_k127_108676_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000002731 162.0
HKD1_k127_108676_8 Belongs to the UPF0297 family - - - 0.00000000000000000000000000003174 118.0
HKD1_k127_108676_9 Protein of unknown function (DUF1292) K07447 - - 0.0000000179 59.0
HKD1_k127_1088280_0 Glycerate kinase family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 535.0
HKD1_k127_1088412_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003997 253.0
HKD1_k127_1098898_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 533.0
HKD1_k127_1098898_1 Metallo-beta-lactamase superfamily - - - 0.0000000000003581 74.0
HKD1_k127_1100141_0 flavodoxin nitric oxide synthase K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0010181,GO:0016491,GO:0016651,GO:0016661,GO:0016662,GO:0016966,GO:0022900,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0050664,GO:0055114,GO:0072593,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 293.0
HKD1_k127_110581_0 Sporulation and spore germination - - - 0.0000000000000000000000000000000000000000000000000000001811 211.0
HKD1_k127_110581_1 COG NOG18757 non supervised orthologous group - - - 0.000000000000000000000000000002652 124.0
HKD1_k127_1120321_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 376.0
HKD1_k127_1120321_1 Formiminotransferase-cyclodeaminase - - - 0.000000000000000000001051 96.0
HKD1_k127_1121606_0 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003442 256.0
HKD1_k127_112260_0 Catalyzes the carbon skeleton rearrangement of L- glutamate to L-threo-3-methylaspartate ((2S,3S)-3- methylaspartate) K19268 - 5.4.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 591.0
HKD1_k127_112260_1 MutL protein - - - 0.000000000000000000000000000000000000000000000008179 175.0
HKD1_k127_1126854_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005415 240.0
HKD1_k127_1126854_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000001538 174.0
HKD1_k127_1126854_2 SEC-C motif - - - 0.000000000000000000000000002949 114.0
HKD1_k127_112924_0 Bacterial regulatory protein, Fis family K06714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 505.0
HKD1_k127_112924_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000009673 182.0
HKD1_k127_1129461_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 548.0
HKD1_k127_1129461_1 Membrane protein insertase, YidC Oxa1 family K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001761 278.0
HKD1_k127_1129461_2 R3H domain protein K06346 - - 0.0000000000000000000000000000000000000000000000000000000000000002313 229.0
HKD1_k127_1129461_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000005675 108.0
HKD1_k127_1129461_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000116 100.0
HKD1_k127_1129461_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000002031 69.0
HKD1_k127_1131038_0 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001425 235.0
HKD1_k127_1131038_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000003932 108.0
HKD1_k127_1131038_2 Thioesterase superfamily protein - - - 0.000004384 54.0
HKD1_k127_1131038_3 Psort location CytoplasmicMembrane, score - - - 0.00009822 47.0
HKD1_k127_1146541_0 PFAM methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004025 233.0
HKD1_k127_1146541_1 Abc transporter K06147 - - 0.0000000000000000000000000000000000000000000000000000000000009376 214.0
HKD1_k127_1146541_2 Protein of unknown function (DUF1456) - - - 0.000000000000000000000000000000000000000000000000000000000001842 213.0
HKD1_k127_1162431_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 488.0
HKD1_k127_1162431_1 P22 coat protein-protein 5 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 334.0
HKD1_k127_1162431_2 - - - - 0.000000000000000000000000000000000000000000000000000000000007803 218.0
HKD1_k127_1162431_4 - - - - 0.0000000000000000000000000151 111.0
HKD1_k127_1169160_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 538.0
HKD1_k127_1170485_0 UPF0210 protein K09157 - - 0.000000000000000000000000000000000000000000000000000000000000000000001404 239.0
HKD1_k127_1170485_1 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000009386 205.0
HKD1_k127_1170485_2 Belongs to the UPF0237 family K07166 - - 0.000000000000000000000000452 109.0
HKD1_k127_1170485_3 RNA polymerase sigma54 factor K03092 - - 0.0000000000000000000007972 98.0
HKD1_k127_1178888_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009063 422.0
HKD1_k127_1178888_1 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003922 266.0
HKD1_k127_1178888_2 maltose O-acetyltransferase K00633,K00661 - 2.3.1.18,2.3.1.79 0.00000000000000000000000000001465 118.0
HKD1_k127_1178888_3 Conserved TM helix - - - 0.0000000000000000004607 91.0
HKD1_k127_1178888_4 - - - - 0.000000101 54.0
HKD1_k127_117893_0 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 312.0
HKD1_k127_117893_1 Domain of Unknown Function (DUF1540) - - - 0.0000000000000005499 79.0
HKD1_k127_1179331_0 ammonia monooxygenase K07120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 332.0
HKD1_k127_1179331_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 0.000000000000000000000000000000000001145 141.0
HKD1_k127_1183293_0 DNA recombination K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000008039 239.0
HKD1_k127_1183293_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000001007 169.0
HKD1_k127_1183746_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 496.0
HKD1_k127_1183746_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000002585 199.0
HKD1_k127_1183945_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.714e-199 626.0
HKD1_k127_1183945_1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007977 321.0
HKD1_k127_1183955_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 406.0
HKD1_k127_1184653_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 365.0
HKD1_k127_1184653_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000006571 117.0
HKD1_k127_1186228_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000007055 224.0
HKD1_k127_1186228_1 Sporulation integral membrane protein YlbJ - - - 0.000000000000001597 81.0
HKD1_k127_1186368_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 606.0
HKD1_k127_1186624_0 coproporphyrinogen III oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 323.0
HKD1_k127_1186624_1 'dna polymerase iii - - - 0.000000000549 60.0
HKD1_k127_1189099_0 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009445 260.0
HKD1_k127_1189099_1 flagellar basal body K02390 - - 0.000000000000000000000000000000000000001381 150.0
HKD1_k127_1189099_2 Flagellar protein (FlbD) K02385 - - 0.000000000000000005855 85.0
HKD1_k127_1190021_0 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000003898 192.0
HKD1_k127_1196498_0 Belongs to the bacterial solute-binding protein 3 family K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000001706 214.0
HKD1_k127_1196498_1 acid ABC transporter K02029,K02030 - - 0.0001124 46.0
HKD1_k127_1197667_0 Aminotransferase class I and II K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007182 276.0
HKD1_k127_1197667_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000007863 65.0
HKD1_k127_1198804_0 Pyridine nucleotide-disulphide oxidoreductase K10797 - 1.3.1.31 3.986e-242 752.0
HKD1_k127_1199051_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 421.0
HKD1_k127_1199051_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000001386 231.0
HKD1_k127_1199051_2 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.0000000000000000000000000000000000000226 146.0
HKD1_k127_1199746_0 Protein of unknown function (DUF1064) - - - 0.000000000000000000000000000002055 125.0
HKD1_k127_1199746_1 Diguanylate cyclase - - - 0.000000000000000000008315 98.0
HKD1_k127_1199966_0 Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002613 232.0
HKD1_k127_1199966_1 Heavy-metal-associated domain - - - 0.000000000000000004666 84.0
HKD1_k127_1208065_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 481.0
HKD1_k127_1212893_0 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000002602 200.0
HKD1_k127_1212893_1 Tryptophan/tyrosine permease family - - - 0.0000000000000000000000000000000000000000000000000000005724 207.0
HKD1_k127_1229623_0 PFAM peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 439.0
HKD1_k127_1229623_1 Membrane transport protein K07088 - - 0.000000000000000000000000000000009527 130.0
HKD1_k127_1229623_2 Prolyl oligopeptidase family K01303 - 3.4.19.1 0.000000002192 58.0
HKD1_k127_1231341_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004501 241.0
HKD1_k127_1231341_1 Cytoplasmic, score 8.87 K03719 - - 0.000000000000000000000000000000000000009597 147.0
HKD1_k127_1234324_0 peptidoglycan binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 433.0
HKD1_k127_1234324_1 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000001416 133.0
HKD1_k127_1235902_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 473.0
HKD1_k127_1235902_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 388.0
HKD1_k127_1235902_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000003197 185.0
HKD1_k127_123785_0 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 319.0
HKD1_k127_123785_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005147 274.0
HKD1_k127_123785_2 Methyltransferase K15460 - 2.1.1.223 0.000000000000000000000000000000000003171 138.0
HKD1_k127_1242027_0 Oligopeptide/dipeptide transporter, C-terminal region K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 465.0
HKD1_k127_1242027_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 396.0
HKD1_k127_1242027_2 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000002805 94.0
HKD1_k127_1250676_0 Psort location CytoplasmicMembrane, score 9.99 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 408.0
HKD1_k127_1250676_1 - - - - 0.00002533 48.0
HKD1_k127_1251973_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 514.0
HKD1_k127_1251973_1 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 337.0
HKD1_k127_1251973_2 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000006172 259.0
HKD1_k127_1253360_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03169 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 580.0
HKD1_k127_1253360_1 Mo-molybdopterin cofactor biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 308.0
HKD1_k127_1253360_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000001564 204.0
HKD1_k127_1253652_0 tigr00255 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 293.0
HKD1_k127_1253652_1 Fibronectin-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003791 260.0
HKD1_k127_1253652_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000002454 252.0
HKD1_k127_1253652_3 Belongs to the UPF0296 family K09777 - - 0.000000000000000000000000000002998 121.0
HKD1_k127_1253652_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000008369 57.0
HKD1_k127_1253652_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000001017 57.0
HKD1_k127_1257009_0 Arsenical pump membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 552.0
HKD1_k127_1257009_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000001687 226.0
HKD1_k127_1257640_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 420.0
HKD1_k127_1257640_1 glucose-1-phosphate adenylyltransferase GlgD subunit K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 340.0
HKD1_k127_1257640_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 294.0
HKD1_k127_1257640_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001268 274.0
HKD1_k127_1257640_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000002255 181.0
HKD1_k127_1259130_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 358.0
HKD1_k127_1259130_1 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000002535 151.0
HKD1_k127_126719_0 TRAP transporter solute receptor TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 392.0
HKD1_k127_126719_1 TRAP transporter, 4TM 12TM fusion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 368.0
HKD1_k127_126719_2 Domain of unknown function (DUF1850) - - - 0.000000000000001082 83.0
HKD1_k127_1268653_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 4.535e-217 685.0
HKD1_k127_1268653_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 311.0
HKD1_k127_1268779_0 Oxidoreductase K07137 - - 3.204e-242 754.0
HKD1_k127_1268779_1 - - - - 0.00000000000000000005475 92.0
HKD1_k127_1272378_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 356.0
HKD1_k127_1272378_1 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002799 270.0
HKD1_k127_1272378_2 Diguanylate cyclase K21022 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000004051 218.0
HKD1_k127_1272378_3 phosphate ABC transporter K02038 - - 0.000000000000000009357 86.0
HKD1_k127_1272493_0 Aromatic amino acid lyase K01745 - 4.3.1.3 5.786e-238 742.0
HKD1_k127_1272493_1 Aminotransferase K10907,K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 414.0
HKD1_k127_1272493_2 PFAM HutP K09683 - - 0.0000000000000000000000000000000000000000007361 160.0
HKD1_k127_1272493_3 PFAM HutP K09683 - - 0.000000000000000000000000000000000000001731 152.0
HKD1_k127_1272493_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000001867 100.0
HKD1_k127_1272501_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 325.0
HKD1_k127_1272501_1 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 308.0
HKD1_k127_1272501_2 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition K06379 - 2.7.11.1 0.0000000000000000000000000000000000000000000000003482 179.0
HKD1_k127_1272501_3 Anti-sigma F factor antagonist K06378 - - 0.00000000000000000000001213 103.0
HKD1_k127_1272501_4 Domain of unknown function (DUF4342) - - - 0.0000000000007392 75.0
HKD1_k127_1272501_5 Psort location CytoplasmicMembrane, score - - - 0.000000003156 57.0
HKD1_k127_1273019_0 Psort location Cytoplasmic, score K06334 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007698 255.0
HKD1_k127_1273019_1 Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000009347 161.0
HKD1_k127_1273019_2 CotJB protein K06333 - - 0.00000000000007844 74.0
HKD1_k127_1273295_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06951 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 282.0
HKD1_k127_1273295_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000000000000000000000001846 143.0
HKD1_k127_1276054_0 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 9.661e-207 650.0
HKD1_k127_1276054_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 393.0
HKD1_k127_1276054_2 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000002194 248.0
HKD1_k127_1276054_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000006559 198.0
HKD1_k127_1276054_4 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000003094 194.0
HKD1_k127_1276054_5 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000009954 158.0
HKD1_k127_1276054_6 DRTGG domain - - - 0.000000000000000000000000000001256 124.0
HKD1_k127_1276054_7 DRTGG domain - - - 0.00000000000000000000000000001498 121.0
HKD1_k127_1276054_8 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000003049 72.0
HKD1_k127_1278556_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 430.0
HKD1_k127_1278556_1 Domain of unknown function (DUF2172) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 393.0
HKD1_k127_1278862_0 import. Responsible for energy coupling to the transport system K10441,K10542 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 393.0
HKD1_k127_1278862_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 370.0
HKD1_k127_1278862_2 C4-dicarboxylate anaerobic carrier - - - 0.00000000000000000000000000000000000000000000000000000000002407 209.0
HKD1_k127_1278862_3 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose K06726 - 5.4.99.62 0.00000000000000000000000000000000000000000000002886 173.0
HKD1_k127_1280083_0 Belongs to the UbiD family K01612 - 4.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 484.0
HKD1_k127_1280083_1 Belongs to the acetokinase family K00929 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761 2.7.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 366.0
HKD1_k127_1280083_2 PFAM Phosphate acetyl butaryl transferase K00634 - 2.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 293.0
HKD1_k127_1283585_0 Collagenase K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 299.0
HKD1_k127_1283585_1 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0009559 51.0
HKD1_k127_1283802_0 Glycoprotease family K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005327 278.0
HKD1_k127_1283802_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000005128 243.0
HKD1_k127_1283802_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000001751 130.0
HKD1_k127_1283802_3 Asp23 family, cell envelope-related function - - - 0.0000000000000000000000001462 110.0
HKD1_k127_1283802_4 stage III sporulation protein AG K06396 - - 0.000000000000008621 81.0
HKD1_k127_1283802_5 Stage III sporulation protein AC K06392 - - 0.000000000005709 66.0
HKD1_k127_1283802_6 Stage III sporulation protein AD K06393 - - 0.0000000001872 66.0
HKD1_k127_1283802_7 TIGRFAM stage III sporulation protein AE K06394 - - 0.0000002405 63.0
HKD1_k127_1283802_8 SpoIIIAH-like protein K06397 - - 0.000001031 59.0
HKD1_k127_1283802_9 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.000001289 52.0
HKD1_k127_130964_0 Transposase - - - 1.305e-207 656.0
HKD1_k127_1316913_0 Efflux ABC transporter, permease protein K02004 - - 2.567e-277 872.0
HKD1_k127_1316913_1 ABC transporter, ATP-binding protein K02003 - - 0.000000000000678 70.0
HKD1_k127_1316913_2 secretion protein - - - 0.0000001183 56.0
HKD1_k127_1319175_0 conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 381.0
HKD1_k127_1321580_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.088e-264 827.0
HKD1_k127_1324831_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 503.0
HKD1_k127_1324831_1 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 413.0
HKD1_k127_1324831_2 transcriptional regulator, RpiR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 320.0
HKD1_k127_1324831_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000005993 231.0
HKD1_k127_1324831_4 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000528 197.0
HKD1_k127_1324831_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000001374 191.0
HKD1_k127_1324831_6 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000005991 189.0
HKD1_k127_1324831_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000008695 178.0
HKD1_k127_1325128_0 MFS_1 like family K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000001053 240.0
HKD1_k127_1325128_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - - 0.0000000000000000000000000000000000000000002133 167.0
HKD1_k127_1327487_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 455.0
HKD1_k127_1332313_0 Belongs to the UPF0061 (SELO) family - - - 4.084e-244 761.0
HKD1_k127_1332313_1 Belongs to the acetokinase family K00929 - 2.7.2.7 0.0000000000000009873 82.0
HKD1_k127_1333964_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 440.0
HKD1_k127_1333964_1 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000361 266.0
HKD1_k127_1334724_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 7.345e-315 968.0
HKD1_k127_1342205_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 341.0
HKD1_k127_1342205_1 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000006215 63.0
HKD1_k127_1342415_0 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 320.0
HKD1_k127_1342415_1 universal stress protein - - - 0.0000000000000000000000000000000000000002844 154.0
HKD1_k127_1344184_0 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 345.0
HKD1_k127_135325_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.89e-273 848.0
HKD1_k127_1355822_0 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 411.0
HKD1_k127_1358410_0 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 392.0
HKD1_k127_1358410_1 histidine kinase HAMP region domain protein K07651,K07652 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 338.0
HKD1_k127_1359293_0 PFAM ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 462.0
HKD1_k127_1359293_1 vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0000000000000000000000000000002399 141.0
HKD1_k127_1360003_0 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 456.0
HKD1_k127_1360003_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 288.0
HKD1_k127_1360003_2 binding-protein-dependent transport K02050,K15552 - - 0.00000000000000000000000000000000482 128.0
HKD1_k127_1363605_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 483.0
HKD1_k127_1363605_1 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 383.0
HKD1_k127_1363605_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 335.0
HKD1_k127_1363605_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000005905 240.0
HKD1_k127_1363605_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000004325 130.0
HKD1_k127_1364573_0 lipoprotein YddW precursor K01189 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 437.0
HKD1_k127_1364668_0 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 313.0
HKD1_k127_1364668_1 PFAM Metallopeptidase family M24 - - - 0.000000000000000000000000000005473 121.0
HKD1_k127_1368684_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000009423 218.0
HKD1_k127_1368684_1 PTS system mannose fructose sorbose family IID component K02796 - - 0.0000000000000000000000000000000001097 142.0
HKD1_k127_1368903_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1270.0
HKD1_k127_1368903_1 Mate efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000006539 197.0
HKD1_k127_1368903_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000001364 152.0
HKD1_k127_1370072_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 6.599e-302 939.0
HKD1_k127_1370072_1 Alpha/beta hydrolase family K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 325.0
HKD1_k127_1370072_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000001247 246.0
HKD1_k127_1370072_3 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000005336 100.0
HKD1_k127_1374169_0 radical SAM protein K07139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 436.0
HKD1_k127_1374169_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009379 240.0
HKD1_k127_1374169_2 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000005302 132.0
HKD1_k127_1375203_0 peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 418.0
HKD1_k127_1375203_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000999 289.0
HKD1_k127_1375203_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001187 279.0
HKD1_k127_1375203_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000001937 201.0
HKD1_k127_137650_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 452.0
HKD1_k127_137786_0 Alanine racemase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 382.0
HKD1_k127_137786_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000004068 197.0
HKD1_k127_137786_2 S-layer homology domain - - - 0.000000000000000000000000000000000000000000008172 175.0
HKD1_k127_1384729_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 423.0
HKD1_k127_1387979_0 Psort location - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001281 254.0
HKD1_k127_1387979_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000007873 216.0
HKD1_k127_1388587_0 ABC transporter, solute-binding protein K11069,K11070 - - 7.045e-222 704.0
HKD1_k127_1388587_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K11072 - 3.6.3.30,3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 430.0
HKD1_k127_1388587_2 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 344.0
HKD1_k127_1388587_3 Integral membrane protein (intg_mem_TP0381) - - - 0.000000000000000000000000000000000000000000000000000000000000011 223.0
HKD1_k127_1388952_0 FtsX-like permease family K02004,K19084 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 356.0
HKD1_k127_1393656_0 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11070 - - 4.636e-208 649.0
HKD1_k127_1393656_1 Abc transporter, permease protein K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 442.0
HKD1_k127_1393656_2 SIS domain protein K19510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005006 265.0
HKD1_k127_1393656_3 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000003472 57.0
HKD1_k127_1394335_0 Major Facilitator K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 338.0
HKD1_k127_1394335_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000767 253.0
HKD1_k127_1394335_2 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000001247 227.0
HKD1_k127_1394335_3 Coat F domain - - - 0.00000000000000000000000000000000000000000000000001666 187.0
HKD1_k127_1394912_0 TIGRFAM ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent K00525 - 1.17.4.1 0.0 1131.0
HKD1_k127_1394912_1 PFAM ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000225 213.0
HKD1_k127_1398212_0 PFAM SpoVR K06415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001099 254.0
HKD1_k127_1398212_1 Adenylate cyclase K05873 - 4.6.1.1 0.0000000000000000000000000000000000000000000007474 171.0
HKD1_k127_1398324_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0022610,GO:0034641,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0051186,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0140030,GO:0140032,GO:1901360,GO:1901564 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 451.0
HKD1_k127_1398324_1 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 396.0
HKD1_k127_1398324_2 Transcriptional regulator K05311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 309.0
HKD1_k127_143982_0 Psort location CytoplasmicMembrane, score - - - 0.0000000004778 65.0
HKD1_k127_1441143_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 520.0
HKD1_k127_1441143_1 C4-dicarboxylate anaerobic carrier - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 459.0
HKD1_k127_1441143_2 HMGL-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 382.0
HKD1_k127_1441143_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00058,K16843 - 1.1.1.26,1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 312.0
HKD1_k127_1441143_4 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 295.0
HKD1_k127_145576_0 ThiS family - - - 0.000000000000003438 78.0
HKD1_k127_145576_1 protein transport into plasma membrane raft K10421,K10422,K10423 GO:0000226,GO:0000278,GO:0000775,GO:0000776,GO:0001578,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0005768,GO:0005794,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0005874,GO:0005875,GO:0005876,GO:0005881,GO:0005882,GO:0006810,GO:0006886,GO:0006996,GO:0007010,GO:0007017,GO:0007026,GO:0007049,GO:0007275,GO:0007349,GO:0007399,GO:0008017,GO:0008092,GO:0008104,GO:0008150,GO:0008270,GO:0009653,GO:0009987,GO:0010638,GO:0010639,GO:0010720,GO:0010975,GO:0010976,GO:0012505,GO:0015031,GO:0015630,GO:0015631,GO:0015833,GO:0016043,GO:0017022,GO:0022008,GO:0030141,GO:0030154,GO:0030424,GO:0030425,GO:0030426,GO:0030427,GO:0031110,GO:0031111,GO:0031112,GO:0031113,GO:0031114,GO:0031116,GO:0031334,GO:0031344,GO:0031346,GO:0031410,GO:0031967,GO:0031975,GO:0031982,GO:0032036,GO:0032271,GO:0032273,GO:0032501,GO:0032502,GO:0032594,GO:0032596,GO:0032886,GO:0032991,GO:0033036,GO:0033043,GO:0033267,GO:0034613,GO:0035371,GO:0036477,GO:0042599,GO:0042802,GO:0042803,GO:0042886,GO:0042995,GO:0043005,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043242,GO:0043244,GO:0043254,GO:0044087,GO:0044089,GO:0044295,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044860,GO:0044861,GO:0045111,GO:0045169,GO:0045184,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0046872,GO:0046907,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048646,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050773,GO:0050789,GO:0050793,GO:0050794,GO:0051010,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051493,GO:0051494,GO:0051495,GO:0051641,GO:0051649,GO:0051668,GO:0051960,GO:0051962,GO:0060284,GO:0061024,GO:0065007,GO:0070507,GO:0070727,GO:0070853,GO:0070854,GO:0071702,GO:0071705,GO:0071840,GO:0072657,GO:0090150,GO:0097447,GO:0097458,GO:0097708,GO:0098687,GO:0099080,GO:0099081,GO:0099503,GO:0099512,GO:0099513,GO:0120025,GO:0120035,GO:0120038,GO:0150034,GO:1900006,GO:1901588,GO:1901879,GO:1901880,GO:1902903,GO:1902904,GO:1902905,GO:1903044,GO:1990752,GO:1990778,GO:2000026 - 0.0000000001383 74.0
HKD1_k127_145576_2 response to antibiotic - - - 0.00001003 51.0
HKD1_k127_1468910_0 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000008238 163.0
HKD1_k127_148366_0 - - - - 0.000000000000000000000000000000000000000000001862 175.0
HKD1_k127_148366_1 FlhB HrpN YscU SpaS Family K04061 - - 0.0000000000000000000000000234 110.0
HKD1_k127_148366_2 PilZ domain - - - 0.0000008022 59.0
HKD1_k127_1483772_0 Domain of unknown function (DUF5058) - - - 0.000000000000000000000000000000000000000000544 162.0
HKD1_k127_1492079_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 501.0
HKD1_k127_1492079_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002683 279.0
HKD1_k127_1503919_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331 - 1.12.1.3,1.6.5.3 1.321e-282 877.0
HKD1_k127_1503919_1 glutamate synthase (NADPH) - - - 1.019e-267 839.0
HKD1_k127_1503919_2 M18 family aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 258.0
HKD1_k127_1503919_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001026 240.0
HKD1_k127_1504231_0 reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 382.0
HKD1_k127_1504231_1 Methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000005461 186.0
HKD1_k127_1509028_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 8.748e-271 844.0
HKD1_k127_1509028_1 AAA ATPase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000001411 220.0
HKD1_k127_1509028_2 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.000000000000000000814 91.0
HKD1_k127_1509547_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.505e-217 694.0
HKD1_k127_1509547_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000388 157.0
HKD1_k127_151283_0 Sigma54 specific transcriptional regulator, Fis family K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 469.0
HKD1_k127_1516047_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 479.0
HKD1_k127_1521908_0 amine oxidase K00274 - 1.4.3.4 2.725e-205 653.0
HKD1_k127_1521908_1 Psort location Cytoplasmic, score 8.87 - - - 0.000000000001289 67.0
HKD1_k127_1521908_2 Hydrogenase maturation protease K03605 - - 0.000001029 52.0
HKD1_k127_1529651_0 n-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000001725 78.0
HKD1_k127_1529651_1 - - - - 0.00000000002801 67.0
HKD1_k127_1529651_2 - - - - 0.00000001716 58.0
HKD1_k127_153387_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 6.661e-253 785.0
HKD1_k127_153387_1 Alpha beta hydrolase K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 378.0
HKD1_k127_153387_2 Psort location Cytoplasmic, score - - - 0.000000000000000000000002944 102.0
HKD1_k127_153387_3 Psort location - - - 0.0000000004693 61.0
HKD1_k127_1536587_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 555.0
HKD1_k127_1536587_1 BioY protein K03523 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 297.0
HKD1_k127_1536587_2 Sigma54 specific transcriptional regulator, Fis family K21405 - - 0.00000000000001489 82.0
HKD1_k127_1536587_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000007158 74.0
HKD1_k127_1544394_0 RyR domain - - - 0.0 1154.0
HKD1_k127_1544394_1 TIGR00266 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 388.0
HKD1_k127_1544394_2 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 331.0
HKD1_k127_1544394_3 Psort location Cytoplasmic, score 8.87 - - - 0.00000000000000000000006436 100.0
HKD1_k127_1545298_0 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses K05339 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 309.0
HKD1_k127_1545298_1 LrgA family K05338 - - 0.000000000000000000003973 95.0
HKD1_k127_1546490_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0003674,GO:0005488,GO:0005515,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0042802,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - 0.0 1357.0
HKD1_k127_1546490_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 450.0
HKD1_k127_1546490_2 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002614 285.0
HKD1_k127_1549103_0 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 345.0
HKD1_k127_1549103_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000002594 110.0
HKD1_k127_155366_0 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 451.0
HKD1_k127_155366_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001041 274.0
HKD1_k127_156913_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 411.0
HKD1_k127_156913_1 TIGRFAM glutamate synthases, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 360.0
HKD1_k127_1587648_0 UPF0182 protein K09118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 304.0
HKD1_k127_1587648_1 Sigma-70 region 3 K03090,K03091 - - 0.0000000000000000000000000000000000000000000007078 169.0
HKD1_k127_1592405_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002773 280.0
HKD1_k127_1592405_1 Archaeal vacuolar-type H -ATPase subunit C K02119 - - 0.00000000000000000000000000000000000000000000000000000009127 203.0
HKD1_k127_1599057_0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000001391 206.0
HKD1_k127_1599057_1 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000001143 160.0
HKD1_k127_1600623_0 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 287.0
HKD1_k127_1600623_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000003392 255.0
HKD1_k127_1600623_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000003472 183.0
HKD1_k127_1627884_0 COG2508, regulator of polyketide synthase expression K09684 - - 0.00000000000000000000000000000000000000000000000000000000000000000004489 245.0
HKD1_k127_1627884_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000005247 130.0
HKD1_k127_1633551_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 473.0
HKD1_k127_1633551_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 383.0
HKD1_k127_1633551_2 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 374.0
HKD1_k127_164044_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 570.0
HKD1_k127_164044_1 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 343.0
HKD1_k127_164346_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 346.0
HKD1_k127_164346_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 318.0
HKD1_k127_1650911_0 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 523.0
HKD1_k127_1650911_1 lactate/malate dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000291 113.0
HKD1_k127_1654910_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 539.0
HKD1_k127_1654910_1 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000006569 156.0
HKD1_k127_165589_0 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 379.0
HKD1_k127_165589_1 peptidase U62, modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008521 263.0
HKD1_k127_1656960_0 amino acid K03294,K03758 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 377.0
HKD1_k127_1656960_1 Competence protein ComEC K02238 - - 0.00000000000000000000000000000008568 131.0
HKD1_k127_1657356_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 426.0
HKD1_k127_1657356_1 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000005154 164.0
HKD1_k127_1657356_2 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000003615 72.0
HKD1_k127_1668423_0 MerR, DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 361.0
HKD1_k127_1668423_1 Protein of unknown function (DUF434) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 310.0
HKD1_k127_1668423_2 'dna polymerase iii - - - 0.0000000000000000000000000000003596 124.0
HKD1_k127_1670816_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 336.0
HKD1_k127_1670816_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001307 267.0
HKD1_k127_1670816_2 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000297 261.0
HKD1_k127_1670816_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000001294 134.0
HKD1_k127_1672440_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 364.0
HKD1_k127_1672440_1 Heavy metal transport detoxification protein - - - 0.000000000000000000000000005198 111.0
HKD1_k127_1672440_2 Protein of unknown function (DUF2512) - - - 0.00004516 48.0
HKD1_k127_1701204_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 497.0
HKD1_k127_1701204_1 ACT domain K01653 - 2.2.1.6 0.00000000003529 66.0
HKD1_k127_1703888_0 PFAM acetate and butyrate kinase K00929 - 2.7.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 400.0
HKD1_k127_1703888_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000007155 183.0
HKD1_k127_1705405_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 357.0
HKD1_k127_1705405_1 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000009562 225.0
HKD1_k127_1705405_2 3-oxoacid CoA-transferase, B subunit K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.0000000000000000000000000006105 114.0
HKD1_k127_1709086_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.135e-242 756.0
HKD1_k127_1709086_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.0000000000000000000001731 96.0
HKD1_k127_1709086_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000002626 98.0
HKD1_k127_1709086_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000457 72.0
HKD1_k127_170913_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 344.0
HKD1_k127_170913_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000001525 214.0
HKD1_k127_1709655_0 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000001792 236.0
HKD1_k127_1709655_1 Penicillin-binding Protein K05515 - 3.4.16.4 0.00000000000000000000000000000000000003939 159.0
HKD1_k127_1709655_2 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000008188 138.0
HKD1_k127_1709655_3 NAD dependent epimerase/dehydratase family - - - 0.000000000000001058 77.0
HKD1_k127_1709655_4 Rod shape-determining protein K03571 - - 0.00000003288 61.0
HKD1_k127_1762609_0 Permease family K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 327.0
HKD1_k127_1784886_0 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007747 342.0
HKD1_k127_1784886_1 PFAM Lysine exporter protein (LYSE YGGA) K06895 - - 0.000000000000000000000000000000000000000000000000000000000001025 214.0
HKD1_k127_179658_0 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.00000000000000000000818 94.0
HKD1_k127_179658_1 PFAM CheW domain protein K03408 - - 0.00000000000004492 78.0
HKD1_k127_179658_2 FlgN protein - - - 0.0000004792 57.0
HKD1_k127_179658_3 chemotaxis K03408 - - 0.0003133 43.0
HKD1_k127_181699_0 glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 332.0
HKD1_k127_181699_1 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000616 199.0
HKD1_k127_181699_2 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000001571 172.0
HKD1_k127_1852632_0 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 510.0
HKD1_k127_1852632_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 507.0
HKD1_k127_1852632_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000004685 227.0
HKD1_k127_1852632_3 Glyco_18 K06306 - - 0.000000000000000000000001608 107.0
HKD1_k127_1853948_0 FMN_bind - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 287.0
HKD1_k127_1853948_1 PFAM C4-dicarboxylate anaerobic carrier-like - - - 0.000000000000000000004035 93.0
HKD1_k127_185409_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1544.0
HKD1_k127_185409_1 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 5.229e-215 670.0
HKD1_k127_185409_2 NifU-like domain - - - 0.0000000000000000000000001156 109.0
HKD1_k127_185409_3 dehydratase - - - 0.000000000000000006878 85.0
HKD1_k127_1854964_0 molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009845 252.0
HKD1_k127_1885200_0 Glycosyltransferase, group 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 356.0
HKD1_k127_1885200_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000004759 178.0
HKD1_k127_1887357_0 SNF2 family N-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 389.0
HKD1_k127_1887357_1 HD containing hydrolase-like enzyme K07023,K08722 - 3.1.3.89 0.00000000000000000000000000000000000000000000000000000000000000007782 227.0
HKD1_k127_1887357_2 SNF2 family N-terminal domain K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000002928 220.0
HKD1_k127_1887357_3 Beta propeller domain - - - 0.000000000000000000000000003587 115.0
HKD1_k127_1887822_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.247e-244 759.0
HKD1_k127_1891597_0 Regulatory protein GntR HTH K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001052 252.0
HKD1_k127_1891597_1 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000003157 87.0
HKD1_k127_1893854_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 362.0
HKD1_k127_1893854_1 Chromate K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000001219 237.0
HKD1_k127_1893854_2 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000007178 219.0
HKD1_k127_1893854_3 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000003528 67.0
HKD1_k127_1894793_0 Psort location Cytoplasmic, score 10.00 K01893 - 6.1.1.22 1.155e-195 616.0
HKD1_k127_1894793_1 ABC transporter, permease protein K17073,K17074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 348.0
HKD1_k127_1894793_2 An automated process has identified a potential problem with this gene model K17073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 334.0
HKD1_k127_1894793_3 ABC transporter K02028,K17074,K17076 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000003999 246.0
HKD1_k127_1905780_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 537.0
HKD1_k127_1905780_1 stage V sporulation protein T K04769 - - 0.0000000000000000000000000000000000000000000000000000000000087 209.0
HKD1_k127_1905780_2 SurA N-terminal domain K03769,K07533 - 5.2.1.8 0.000000000000000000000000000000000000000000002394 177.0
HKD1_k127_1929301_0 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000003271 148.0
HKD1_k127_1929301_1 S4 domain protein - - - 0.0000000000000000000000000000000001233 138.0
HKD1_k127_1929301_2 peptidase - - - 0.000000000000000000006243 95.0
HKD1_k127_1943826_0 PFAM PilT protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 411.0
HKD1_k127_1943826_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 312.0
HKD1_k127_1943826_2 PFAM Transcription factor CarD K07736 - - 0.0000000000000000000000000000000000000000000000000000002588 198.0
HKD1_k127_1943826_3 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000000000131 187.0
HKD1_k127_1943826_4 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000008809 83.0
HKD1_k127_1943826_5 Domain of unknown function (DUF4363) - - - 0.00000000001099 70.0
HKD1_k127_1990177_0 CoA-substrate-specific enzyme activase - - - 1.707e-227 714.0
HKD1_k127_199317_0 S-layer homology domain - - - 0.000004329 51.0
HKD1_k127_20035_0 Cell envelope-related transcriptional attenuator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 374.0
HKD1_k127_2008067_0 C4-dicarboxylate anaerobic carrier - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 514.0
HKD1_k127_202020_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 301.0
HKD1_k127_202020_1 COG COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.0000000000000000000000000000000000000000002302 163.0
HKD1_k127_202094_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 446.0
HKD1_k127_202094_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000001634 113.0
HKD1_k127_2026807_0 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005104 229.0
HKD1_k127_2026807_1 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000011 200.0
HKD1_k127_203258_0 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 384.0
HKD1_k127_203258_1 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16783,K16785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 363.0
HKD1_k127_203258_2 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 344.0
HKD1_k127_203258_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009223 279.0
HKD1_k127_203258_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000001748 211.0
HKD1_k127_203258_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000007451 194.0
HKD1_k127_203258_6 QueT transporter - - - 0.00000000000000000000000004391 111.0
HKD1_k127_203258_7 Transcriptional regulator, LysR family K21900 - - 0.00001579 49.0
HKD1_k127_203948_0 Potassium uptake protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 286.0
HKD1_k127_203948_1 potassium uptake protein, TrkH family K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001646 261.0
HKD1_k127_203948_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000376 211.0
HKD1_k127_203948_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000003399 149.0
HKD1_k127_209957_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 477.0
HKD1_k127_209957_1 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 301.0
HKD1_k127_209957_2 Aminotransferase - - - 0.000000000000001861 77.0
HKD1_k127_2114073_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 499.0
HKD1_k127_2114073_1 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 479.0
HKD1_k127_2128302_0 biosynthesis protein ThiH K03150 - 4.1.99.19 2.555e-240 745.0
HKD1_k127_2128302_1 Iron-only hydrogenase maturation rSAM protein HydE K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000002847 171.0
HKD1_k127_2128651_0 Domain of unknown function (DUF2935) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 373.0
HKD1_k127_2128651_1 Cytidine monophosphokinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 293.0
HKD1_k127_2128651_2 Belongs to the pyridoxine kinase family K00868 - 2.7.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000001898 269.0
HKD1_k127_2128651_3 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step K05985 - 3.1.26.8 0.0000000000000000000000000000000000000000000000000000000000000222 219.0
HKD1_k127_2128651_4 G5 domain protein - - - 0.00000000000000000000000000000000000000000000000000007712 195.0
HKD1_k127_2128651_5 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000004852 140.0
HKD1_k127_2128651_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000004921 60.0
HKD1_k127_2130695_0 - - - - 0.000000000000000000000000000000000000000000000000002482 197.0
HKD1_k127_2135962_0 pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 518.0
HKD1_k127_2135962_1 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 445.0
HKD1_k127_2135962_2 Belongs to the acetokinase family K00929 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761 2.7.2.7 0.000000000000000000000000000000000000000000000000000000000003158 211.0
HKD1_k127_2135962_3 bacterial-type flagellum organization - - - 0.000000000000000000000000000000000000000000349 162.0
HKD1_k127_2135962_4 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000004983 140.0
HKD1_k127_2135962_5 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.00000000000000000000000001315 111.0
HKD1_k127_2135962_6 bacterial-type flagellum organization - - - 0.000000000000000004143 85.0
HKD1_k127_2144251_0 BadF BadG BcrA BcrD - - - 0.0 1070.0
HKD1_k127_2144251_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 574.0
HKD1_k127_2144251_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 450.0
HKD1_k127_2144251_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000002564 199.0
HKD1_k127_214952_0 Psort location Cytoplasmic, score 9.98 K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 561.0
HKD1_k127_214952_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 413.0
HKD1_k127_2150_0 LytTr DNA-binding domain K02477 - - 0.00001587 55.0
HKD1_k127_2150_1 Nuclease-related domain - - - 0.00002848 47.0
HKD1_k127_215684_0 FtsX-like permease family K02004 - - 3.41e-304 944.0
HKD1_k127_2188752_0 PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 3.265e-196 616.0
HKD1_k127_219101_0 Psort location CytoplasmicMembrane, score 10.00 K03458 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 589.0
HKD1_k127_219101_1 Involved in chromosome partitioning - - - 0.0000000001514 63.0
HKD1_k127_2209222_0 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 407.0
HKD1_k127_2209222_1 FCD - - - 0.000000000000003698 77.0
HKD1_k127_2209222_2 C4-dicarboxylate anaerobic carrier - - - 0.000000003827 59.0
HKD1_k127_2210826_0 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008361 378.0
HKD1_k127_2210826_1 auxin efflux carrier K07088 - - 0.0000000000000000000006033 102.0
HKD1_k127_2212458_0 Methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 346.0
HKD1_k127_2212458_1 Methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000008098 204.0
HKD1_k127_2212898_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 6.54e-250 773.0
HKD1_k127_22286_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 377.0
HKD1_k127_22286_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003081 267.0
HKD1_k127_22286_2 Psort location Cytoplasmic, score K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000003102 253.0
HKD1_k127_22286_3 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000005564 164.0
HKD1_k127_22286_4 - - - - 0.000000000000000000000000000000000003461 139.0
HKD1_k127_224380_0 SdpI/YhfL protein family - - - 0.000000000000000000000000000000000000000000000000000000000000144 218.0
HKD1_k127_224380_1 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000001128 142.0
HKD1_k127_224380_2 PFAM ABC transporter substrate binding protein K01989 - - 0.000000000004869 70.0
HKD1_k127_2247250_0 YycH protein - - - 0.0000000000000000000000000000000000005194 150.0
HKD1_k127_2247250_1 YycH protein - - - 0.0000000000000000000000000000006357 130.0
HKD1_k127_2247684_0 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000003572 136.0
HKD1_k127_2279542_0 aconitate hydratase K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 544.0
HKD1_k127_2292813_0 stage III sporulation protein AA K06390 - - 0.0000000000000000000000000000000000000000000004266 171.0
HKD1_k127_2292813_1 Stage III sporulation protein AC K06392 - - 0.0000000000000000003194 89.0
HKD1_k127_2295238_0 amidohydrolase K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 309.0
HKD1_k127_2295238_1 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004089 264.0
HKD1_k127_2295238_2 Molecular chaperone, DnaJ - - - 0.000000000000000000000000000000000000000002713 162.0
HKD1_k127_2295238_3 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000004797 113.0
HKD1_k127_2295238_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000004765 78.0
HKD1_k127_2309394_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 379.0
HKD1_k127_2309394_1 Serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000002016 263.0
HKD1_k127_2309394_2 GntP family permease K03299 - - 0.000000004514 57.0
HKD1_k127_2314546_0 Alpha-amylase domain K01187,K01200 - 3.2.1.20,3.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 471.0
HKD1_k127_2330428_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 364.0
HKD1_k127_2330428_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 306.0
HKD1_k127_2330428_2 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR K06383 - - 0.0000000000002041 78.0
HKD1_k127_2330428_3 sporulation protein, YlmC YmxH family - - - 0.000000000622 63.0
HKD1_k127_2360358_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 591.0
HKD1_k127_2372363_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 519.0
HKD1_k127_2372363_1 DMT(Drug metabolite transporter) superfamily permease - - - 0.0000000000000000000000000000000000000000000000000000006043 204.0
HKD1_k127_2372363_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 - - - 0.0000000000000000000000000000000000000006177 153.0
HKD1_k127_2378690_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 437.0
HKD1_k127_2378690_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000004217 99.0
HKD1_k127_2380154_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 451.0
HKD1_k127_2380154_1 C4-dicarboxylate anaerobic carrier - - - 0.0000000000000000000000000000000000000006005 153.0
HKD1_k127_2380154_2 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000005733 138.0
HKD1_k127_2382143_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 349.0
HKD1_k127_244201_0 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000009494 166.0
HKD1_k127_244201_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000006974 145.0
HKD1_k127_244201_2 acetyltransferase - - - 0.00000000000000000000000000003991 127.0
HKD1_k127_2447766_0 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 547.0
HKD1_k127_2447766_1 OsmC-like protein - - - 0.0000000000000000000000000000000000002401 145.0
HKD1_k127_2447766_2 Chloride transporter ClC family - - - 0.00000105 51.0
HKD1_k127_2448655_0 MobA-like NTP transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000001364 221.0
HKD1_k127_2448655_1 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000173 153.0
HKD1_k127_2448655_2 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000007175 101.0
HKD1_k127_2448655_3 molybdopterin binding domain - - - 0.000000000000005198 74.0
HKD1_k127_2449784_0 TIGRFAM citrate H symporter, CitMHS family K03300 - - 2.486e-199 630.0
HKD1_k127_2449784_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 456.0
HKD1_k127_2449784_2 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase K01910 - 6.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 431.0
HKD1_k127_2449784_3 Covalent carrier of the coenzyme of citrate lyase K01646 - - 0.000000000000000000000001782 106.0
HKD1_k127_2449784_4 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000002249 95.0
HKD1_k127_2456159_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 9.606e-262 826.0
HKD1_k127_2456159_1 ComF family K02242 - - 0.000000000000000000000000000000000000000000000000000001537 200.0
HKD1_k127_2456159_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000001655 153.0
HKD1_k127_2456159_3 Polysaccharide biosynthesis protein K06409 - - 0.0000000000000000000000000000002829 125.0
HKD1_k127_24621_0 phospholipase C K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 340.0
HKD1_k127_24621_1 VTC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 297.0
HKD1_k127_24621_2 Domain of unknown function (DUF4956) - - - 0.0000000000000000000000000000000000008687 143.0
HKD1_k127_24621_3 PFAM ATP dependent DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000001311 62.0
HKD1_k127_24621_4 PFAM ATP dependent DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000004314 55.0
HKD1_k127_246879_0 Radical SAM K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 502.0
HKD1_k127_246879_1 ADP-ribosylglycohydrolase - - - 0.0001163 49.0
HKD1_k127_2495331_0 hmm pf00294 K00852,K16328 - 2.7.1.15,2.7.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 506.0
HKD1_k127_2495331_1 FMN binding - - - 0.00000000000000000000000000000000000000000573 160.0
HKD1_k127_2495331_2 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000001713 116.0
HKD1_k127_2495331_3 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000158 44.0
HKD1_k127_2523058_0 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 464.0
HKD1_k127_2523058_1 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000001091 175.0
HKD1_k127_2528246_0 formate acetyltransferase K00656 - 2.3.1.54 0.0 1095.0
HKD1_k127_2528246_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 5.043e-235 745.0
HKD1_k127_2528246_2 L-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 587.0
HKD1_k127_2528246_3 GntR domain protein K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 295.0
HKD1_k127_2528246_4 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000873 290.0
HKD1_k127_2528246_5 YbaK proline--tRNA ligase associated domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000295 224.0
HKD1_k127_2528246_6 Membrane - - - 0.000000002353 65.0
HKD1_k127_2529053_0 Penicillin-binding Protein K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 514.0
HKD1_k127_2529053_1 Belongs to the ParA family K03609 GO:0000910,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0032506,GO:0036214,GO:0051179,GO:0051301,GO:0061640 - 0.0000000000005114 78.0
HKD1_k127_25363_0 D-galactarate dehydratase altronate hydrolase K16850 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 445.0
HKD1_k127_25363_1 SAF K16849 - 4.2.1.7 0.00000000000000001564 84.0
HKD1_k127_2565691_0 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 607.0
HKD1_k127_2565691_1 Methenyltetrahydrofolate cyclohydrolase - - - 0.0000000000000000000000000000000000005831 143.0
HKD1_k127_2567844_0 type II secretion pathway protein E K01509 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 359.0
HKD1_k127_2567844_1 Domain of unknown function (DUF4860) - - - 0.00000000000000001768 88.0
HKD1_k127_258009_0 Psort location Cytoplasmic, score K01585 - 4.1.1.19 3.527e-243 758.0
HKD1_k127_258009_1 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 4.288e-216 675.0
HKD1_k127_258009_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 478.0
HKD1_k127_258009_3 2-dehydropantoate 2-reductase activity K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 362.0
HKD1_k127_258009_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000007891 134.0
HKD1_k127_2585204_0 PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 385.0
HKD1_k127_2585204_1 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000009069 268.0
HKD1_k127_2585204_2 Thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000287 246.0
HKD1_k127_2585204_3 Cyclic-di-AMP receptor - - - 0.00000000000000000000000000001974 120.0
HKD1_k127_2585204_4 Ferredoxin - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.0000000000000000000000001783 105.0
HKD1_k127_2585204_5 Orn Lys Arg decarboxylase major K01585 - 4.1.1.19 0.0000000000000729 75.0
HKD1_k127_2585204_6 Fe-S oxidoreductase - - - 0.00000136 50.0
HKD1_k127_2611312_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 375.0
HKD1_k127_2611312_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000008071 231.0
HKD1_k127_2611312_2 Phage integrase, N-terminal SAM-like domain - - - 0.000132 48.0
HKD1_k127_2653160_0 cell envelope-related function transcriptional attenuator - - - 0.0000000000000000000000000000000000000000000000000000000000000005303 230.0
HKD1_k127_2653160_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000001634 199.0
HKD1_k127_2653160_2 PFAM small acid-soluble spore protein alpha beta type K06421 - - 0.0002323 46.0
HKD1_k127_2655485_0 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000001599 167.0
HKD1_k127_2655485_1 family 18 K06306 - - 0.0000000001804 61.0
HKD1_k127_2683143_0 UPF0182 protein K09118 - - 3.49e-229 722.0
HKD1_k127_2686853_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 578.0
HKD1_k127_2686853_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 520.0
HKD1_k127_2686853_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 453.0
HKD1_k127_2686853_3 sirohydrochlorin cobaltochelatase K02190 - 4.99.1.3 0.000000000000000000000000000000000000000000000002651 182.0
HKD1_k127_2686853_4 Cysteine-rich small domain K07162 - - 0.00000000000000000000000000000008775 125.0
HKD1_k127_2692063_0 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002256 256.0
HKD1_k127_2692063_1 Radical_SAM C-terminal domain - - - 0.00000000000000000000000001242 111.0
HKD1_k127_2692783_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.161e-262 831.0
HKD1_k127_2692783_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 540.0
HKD1_k127_2692783_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 378.0
HKD1_k127_2692783_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000001833 271.0
HKD1_k127_2692783_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000001093 143.0
HKD1_k127_2692783_5 S4 RNA-binding domain - - - 0.000000000000000000000000006039 111.0
HKD1_k127_2694786_0 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 415.0
HKD1_k127_2694786_1 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 316.0
HKD1_k127_2704514_0 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 410.0
HKD1_k127_2704514_1 Cobalt ABC transporter, permease protein CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 295.0
HKD1_k127_2704514_2 ABC-type cobalt transport system ATPase component K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 286.0
HKD1_k127_2713488_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 4.521e-319 984.0
HKD1_k127_2718134_0 xyloglucan:xyloglucosyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 319.0
HKD1_k127_2718134_1 TaqI-like C-terminal specificity domain K07317 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000002395 210.0
HKD1_k127_2718241_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 433.0
HKD1_k127_2719198_0 Belongs to the serine threonine dehydratase family. DsdA subfamily K01753 - 4.3.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 281.0
HKD1_k127_2719198_1 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001486 270.0
HKD1_k127_2721561_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 590.0
HKD1_k127_2721561_1 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 374.0
HKD1_k127_2721561_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000001839 202.0
HKD1_k127_2723882_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 529.0
HKD1_k127_2723882_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 443.0
HKD1_k127_2723882_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000001531 137.0
HKD1_k127_2724574_0 NADH flavin oxidoreductase NADH oxidase - - - 4.108e-223 694.0
HKD1_k127_2724574_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000005189 229.0
HKD1_k127_2724574_2 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000002147 194.0
HKD1_k127_2737389_0 sigma factor activity K03091,K03093 - - 0.00000000000000000000000000000000000000000000000000000000000000000001088 241.0
HKD1_k127_2737389_1 Anti-sigma factor N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000009296 222.0
HKD1_k127_2737389_2 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000007943 48.0
HKD1_k127_2737539_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 370.0
HKD1_k127_2737539_1 - - - - 0.00000000000000000005997 92.0
HKD1_k127_2737539_2 PFAM Rubrerythrin - - - 0.00000000000001839 74.0
HKD1_k127_2738975_0 Cache domain K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 455.0
HKD1_k127_2738975_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 300.0
HKD1_k127_2741678_0 Rhodanese Homology Domain K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 300.0
HKD1_k127_2762375_0 alcohol dehydrogenase K18012 - 1.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 374.0
HKD1_k127_2762375_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000007181 197.0
HKD1_k127_2803509_0 Protease prsW family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007514 274.0
HKD1_k127_2824815_0 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001008 272.0
HKD1_k127_2824815_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000004517 215.0
HKD1_k127_2826279_0 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 347.0
HKD1_k127_2826279_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006441 259.0
HKD1_k127_2843667_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 291.0
HKD1_k127_2843667_1 Belongs to the binding-protein-dependent transport system permease family K05832 - - 0.000000000000000000000000000000000000000154 154.0
HKD1_k127_2846901_0 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000002458 183.0
HKD1_k127_2846901_1 flagellar motor switch protein K02416 - - 0.00000000000000000000000000007933 119.0
HKD1_k127_2880147_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 306.0
HKD1_k127_2880147_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000005672 173.0
HKD1_k127_2880147_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000004904 163.0
HKD1_k127_2880147_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000009494 166.0
HKD1_k127_2880147_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000000000001028 148.0
HKD1_k127_2880147_5 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000000000004134 132.0
HKD1_k127_2883336_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 370.0
HKD1_k127_2883336_1 AAA ATPase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007821 240.0
HKD1_k127_290112_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009801 434.0
HKD1_k127_2902547_0 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003438 279.0
HKD1_k127_298072_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001038 273.0
HKD1_k127_3007590_0 stage II sporulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 336.0
HKD1_k127_3007590_1 Iron only hydrogenase large subunit, C-terminal domain K00533 - 1.12.7.2 0.000000000000000000000000000000000000000001103 160.0
HKD1_k127_3012168_0 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 503.0
HKD1_k127_3012168_1 Allophanate hydrolase subunit 1 K06351 - - 0.00000000000000000000000000000000005296 136.0
HKD1_k127_3012168_2 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000001151 83.0
HKD1_k127_3022570_0 ABC-type sugar transport system, ATPase component K10441 - 3.6.3.17 5.629e-214 675.0
HKD1_k127_3022570_1 ABC-type sugar transport system, periplasmic K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 290.0
HKD1_k127_3032494_0 diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000000009068 184.0
HKD1_k127_3032494_1 chemotaxis response regulator protein-glutamate methylesterase 1 - - - 0.00000000000000000001793 96.0
HKD1_k127_3053900_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 290.0
HKD1_k127_3053900_1 ABC transporter substrate binding protein K01989 - - 0.00000001864 59.0
HKD1_k127_3059591_0 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 529.0
HKD1_k127_3059591_1 PFAM major facilitator superfamily MFS_1 K08170 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 443.0
HKD1_k127_306157_0 Oxidoreductase K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 586.0
HKD1_k127_306157_1 HI0933 family K07007 - - 0.0000000000000000000000000000000000004065 143.0
HKD1_k127_307088_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 420.0
HKD1_k127_3079524_0 Psort location CytoplasmicMembrane, score 10.00 K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 375.0
HKD1_k127_3079524_1 S-layer homology domain - - - 0.00000000000000000000000000000000002001 148.0
HKD1_k127_3079524_2 ABC transporter K02003 - - 0.000000000002313 67.0
HKD1_k127_30942_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.135e-262 813.0
HKD1_k127_30942_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 511.0
HKD1_k127_30942_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 387.0
HKD1_k127_30942_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 319.0
HKD1_k127_30942_4 PFAM single-strand binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 293.0
HKD1_k127_30942_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000003536 193.0
HKD1_k127_3121279_0 Peptidase family M20/M25/M40 - - - 0.000000000000000000000000001286 116.0
HKD1_k127_3121279_1 SMART AAA ATPase K06923 - - 0.0000001041 59.0
HKD1_k127_3123668_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.579e-304 956.0
HKD1_k127_3123668_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 383.0
HKD1_k127_3123668_2 Preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000005592 102.0
HKD1_k127_3129573_0 Phosphorylase superfamily K03784 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 333.0
HKD1_k127_3129573_1 ADP-ribosylglycohydrolase - - - 0.000000000000000000000008089 104.0
HKD1_k127_3136010_0 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000005132 232.0
HKD1_k127_3136010_1 PFAM MaoC domain protein dehydratase K17865 - 4.2.1.55 0.000000000000000000000000000000000000000000000000000000004698 202.0
HKD1_k127_3136010_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000005436 160.0
HKD1_k127_3140024_0 belongs to the iron- containing alcohol dehydrogenase family K04072 - 1.1.1.1,1.2.1.10 0.0 1404.0
HKD1_k127_3145486_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 499.0
HKD1_k127_3145486_1 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 439.0
HKD1_k127_3145486_2 Transposase domain (DUF772) - - - 0.0000000000000000000000000000000000000001704 152.0
HKD1_k127_3146778_0 Beta propeller domain - - - 0.00000000000000000000000000000000000000000004961 173.0
HKD1_k127_3146778_1 Domain of Unknown Function (DUF1540) - - - 0.000001893 53.0
HKD1_k127_3162412_0 chemotaxis protein K03410 - - 0.00000000000000000000000000000000000000000000000000000004767 202.0
HKD1_k127_3162412_1 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000001451 175.0
HKD1_k127_3162412_2 S-layer homology domain - - - 0.0000000000001588 76.0
HKD1_k127_3172646_0 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 291.0
HKD1_k127_3172646_1 Histidine kinase K07650 - 2.7.13.3 0.000000000000000034 82.0
HKD1_k127_3182172_0 ABC transporter K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 580.0
HKD1_k127_3182172_1 Abc transporter K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 533.0
HKD1_k127_31839_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03169 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 496.0
HKD1_k127_3204511_0 elongation factor G K02355 - - 1.143e-247 777.0
HKD1_k127_3204511_1 Protein of unknown function (DUF445) - - - 0.0000000000000000000000000005932 118.0
HKD1_k127_3229911_0 DNA replication protein DnaD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007947 257.0
HKD1_k127_3229911_1 DNA replication protein K02315 - - 0.000000000000000000000000000003555 124.0
HKD1_k127_3229966_0 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000008682 176.0
HKD1_k127_32531_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 386.0
HKD1_k127_32531_1 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 355.0
HKD1_k127_32531_2 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 GO:0003674,GO:0003824,GO:0003855,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019752,GO:0032787,GO:0042537,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002282 283.0
HKD1_k127_32531_3 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004675 269.0
HKD1_k127_326843_0 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005752 248.0
HKD1_k127_326843_1 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000092 179.0
HKD1_k127_326843_2 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000001811 72.0
HKD1_k127_3284922_0 DAK2 domain fusion protein YloV K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 592.0
HKD1_k127_3284922_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 475.0
HKD1_k127_3284922_2 Asp23 family, cell envelope-related function - - - 0.000000000000000000000000000000000000000001155 159.0
HKD1_k127_3298206_0 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 479.0
HKD1_k127_3298206_1 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006203 273.0
HKD1_k127_3311354_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 2.535e-217 680.0
HKD1_k127_3325889_0 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 472.0
HKD1_k127_3325889_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 466.0
HKD1_k127_3325889_2 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 377.0
HKD1_k127_3325889_3 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.00000000000001033 74.0
HKD1_k127_3326254_0 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001844 254.0
HKD1_k127_3326254_1 - - - - 0.00000003725 57.0
HKD1_k127_3368572_0 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 438.0
HKD1_k127_3368572_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002545 268.0
HKD1_k127_3368936_0 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000002747 177.0
HKD1_k127_3368936_1 acetolactate synthase large subunit K01652 - 2.2.1.6 0.00000000000000000000000000003697 120.0
HKD1_k127_3368936_2 Psort location Cytoplasmic, score - - - 0.000000000002243 70.0
HKD1_k127_3381806_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.04e-270 838.0
HKD1_k127_3391342_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 518.0
HKD1_k127_3391342_1 amino acid ABC transporter K02029,K16962 - - 0.00000000000000000000000000000000000000000000000000000000000001042 223.0
HKD1_k127_3391342_2 GNAT family - - - 0.00000000000000000000000004587 112.0
HKD1_k127_3391342_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000001663 96.0
HKD1_k127_339711_0 Methyltransferase K15460 - 2.1.1.223 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 338.0
HKD1_k127_339711_1 ABC transporter K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 314.0
HKD1_k127_3397798_0 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 484.0
HKD1_k127_3398182_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000961 392.0
HKD1_k127_3398182_1 Adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000005232 196.0
HKD1_k127_3398182_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000001211 174.0
HKD1_k127_3398182_3 Belongs to the phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000002672 116.0
HKD1_k127_3412371_0 zinc-ribbon family - - - 0.0000000000000000000000000000009036 125.0
HKD1_k127_3412371_1 MmcQ-like protein - - - 0.0000000000000000000000000005284 119.0
HKD1_k127_3412371_2 S-layer homology domain - - - 0.00000000000000000000000001007 112.0
HKD1_k127_3416345_0 NADH flavin oxidoreductase NADH oxidase - - - 8.251e-261 810.0
HKD1_k127_3416345_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 449.0
HKD1_k127_3427662_0 Heat shock 70 kDa protein K04043 - - 5.59e-215 673.0
HKD1_k127_3427662_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 357.0
HKD1_k127_3427662_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000002029 148.0
HKD1_k127_3429831_0 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 332.0
HKD1_k127_3429831_1 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000003047 182.0
HKD1_k127_3429831_2 Involved in chromosome partitioning - - - 0.00000000000000000000000000000000000000000003702 169.0
HKD1_k127_3439933_0 C4-dicarboxylate anaerobic carrier - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 414.0
HKD1_k127_3439933_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000001602 149.0
HKD1_k127_3449529_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 440.0
HKD1_k127_3449529_1 Methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 371.0
HKD1_k127_3449529_2 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 302.0
HKD1_k127_3456010_0 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 475.0
HKD1_k127_3456010_1 peptidase, M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 447.0
HKD1_k127_3456333_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 387.0
HKD1_k127_3456333_1 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate K00674,K05822 - 2.3.1.117,2.3.1.89 0.00000000000000000000000000009337 116.0
HKD1_k127_346633_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.932e-272 849.0
HKD1_k127_346633_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 282.0
HKD1_k127_346633_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000001008 178.0
HKD1_k127_346633_3 YmaF family - - - 0.00000000000000000000000000000000000000000000001585 173.0
HKD1_k127_3478759_0 Glycosyl hydrolase family 26 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 403.0
HKD1_k127_3478759_1 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000001104 169.0
HKD1_k127_348829_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 5.387e-199 632.0
HKD1_k127_348829_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 336.0
HKD1_k127_348829_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000008268 170.0
HKD1_k127_3501151_0 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 362.0
HKD1_k127_3501151_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 336.0
HKD1_k127_3501151_2 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000003219 246.0
HKD1_k127_350482_0 Spore photoproduct lyase K03716 GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0016829,GO:0016830,GO:0043167,GO:0043169,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0070283,GO:0140097 4.1.99.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 525.0
HKD1_k127_350482_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000004702 209.0
HKD1_k127_3516126_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 527.0
HKD1_k127_3516126_1 ABC transporter permease K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 489.0
HKD1_k127_3516767_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 471.0
HKD1_k127_3516767_1 domain protein K06959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 284.0
HKD1_k127_3518058_0 Protein of unknown function (DUF445) - - - 0.000000000000000000002596 106.0
HKD1_k127_351954_0 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 362.0
HKD1_k127_351954_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000478 166.0
HKD1_k127_3531608_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 540.0
HKD1_k127_3531608_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 305.0
HKD1_k127_35444_0 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 391.0
HKD1_k127_3551762_0 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 360.0
HKD1_k127_3551762_1 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000001034 243.0
HKD1_k127_3551762_2 ABC-type nitrate sulfonate bicarbonate transport - - - 0.0000000000000000000000000000000000000000000000003062 177.0
HKD1_k127_355636_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 370.0
HKD1_k127_355636_1 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000000004727 177.0
HKD1_k127_355636_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000001012 146.0
HKD1_k127_355636_3 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000004979 95.0
HKD1_k127_3567512_0 permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 369.0
HKD1_k127_3567512_1 redox-active disulfide protein 2 - - - 0.00000000000000000000000000000001192 128.0
HKD1_k127_3567512_2 PFAM regulatory protein ArsR K03892 - - 0.0000000000000000000000000000004147 124.0
HKD1_k127_357894_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 392.0
HKD1_k127_357894_1 - - - - 0.0000000000000001001 82.0
HKD1_k127_358562_0 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 360.0
HKD1_k127_358562_1 Glycosyltransferase, group 2 family protein - - - 0.000000000000001145 78.0
HKD1_k127_3598132_0 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004571 278.0
HKD1_k127_3598132_1 Domain of Unknown function (DUF542) K07322 - - 0.00000000000000000000000000000000000001425 146.0
HKD1_k127_360694_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 3.918e-218 685.0
HKD1_k127_360694_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000007831 61.0
HKD1_k127_361598_0 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 322.0
HKD1_k127_36326_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.198e-195 619.0
HKD1_k127_36326_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 330.0
HKD1_k127_36326_2 50S ribosomal protein L31 K02909 - - 0.000000000000000000000000000000002876 128.0
HKD1_k127_36326_3 Thioredoxin-like [2Fe-2S] ferredoxin - - - 0.00000000000000000000000214 104.0
HKD1_k127_3635284_0 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 296.0
HKD1_k127_3635284_1 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000001485 217.0
HKD1_k127_3638095_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 557.0
HKD1_k127_3638095_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000004779 124.0
HKD1_k127_3639260_0 pyrroloquinoline quinone binding - - - 1.618e-246 766.0
HKD1_k127_3639260_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000005355 234.0
HKD1_k127_3654211_0 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 445.0
HKD1_k127_3654211_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 341.0
HKD1_k127_3654211_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000007715 160.0
HKD1_k127_3658388_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.895e-283 876.0
HKD1_k127_3662645_0 Histidyl-tRNA synthetase K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003326 278.0
HKD1_k127_3662645_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000001795 192.0
HKD1_k127_3662999_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 532.0
HKD1_k127_3662999_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 353.0
HKD1_k127_3662999_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 304.0
HKD1_k127_3662999_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000007615 220.0
HKD1_k127_3662999_4 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000001537 173.0
HKD1_k127_367196_0 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003082 277.0
HKD1_k127_367196_1 Cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002752 265.0
HKD1_k127_367196_2 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000009223 195.0
HKD1_k127_367196_3 heptaprenyl diphosphate synthase K00805 - 2.5.1.30 0.000000000000003285 78.0
HKD1_k127_367196_4 Psort location CytoplasmicMembrane, score 9.75 - - - 0.000000000007651 68.0
HKD1_k127_3681687_0 helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 374.0
HKD1_k127_3681883_0 Dinuclear metal center protein, YbgI family - - - 0.00000000000000000000000000000000000000000000000000000001144 206.0
HKD1_k127_3681883_1 SAM-dependent methyltransferase K06967 - 2.1.1.217 0.000001624 53.0
HKD1_k127_3682434_0 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 573.0
HKD1_k127_3682434_1 Phosphate acetyl/butaryl transferase K00634 - 2.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005468 302.0
HKD1_k127_3682434_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000002999 178.0
HKD1_k127_368440_0 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002738 232.0
HKD1_k127_3685655_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1437.0
HKD1_k127_3685655_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000001604 54.0
HKD1_k127_3708229_0 ATPase MipZ - - - 0.0000000000000000000000000000000000000000000000000000000006579 208.0
HKD1_k127_3708229_1 Chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000007652 186.0
HKD1_k127_3708229_2 NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.00000000000000306 75.0
HKD1_k127_3709088_0 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 458.0
HKD1_k127_3709088_1 sugar fermentation stimulation protein K06206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 349.0
HKD1_k127_3709088_2 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000002911 114.0
HKD1_k127_3710517_0 Radical SAM K04034 - 1.21.98.3 0.000000000000000000000000000009496 120.0
HKD1_k127_3710517_1 ADP-ribosylglycohydrolase - - - 0.00000000001075 71.0
HKD1_k127_3710517_2 ADP-ribosylglycohydrolase - - - 0.000007015 53.0
HKD1_k127_372069_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.622e-216 678.0
HKD1_k127_372069_1 Na H antiporter K03315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 387.0
HKD1_k127_3723262_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 419.0
HKD1_k127_3723262_1 Glutaredoxin - - - 0.000000000000000000000000001494 112.0
HKD1_k127_3723262_2 - - - - 0.0000009622 53.0
HKD1_k127_3733522_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.155e-265 828.0
HKD1_k127_3733522_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000007104 135.0
HKD1_k127_3733522_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000001274 115.0
HKD1_k127_3739446_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000001578 163.0
HKD1_k127_3739446_1 Bacterial Ig-like domain - - - 0.0000000000000000000002315 107.0
HKD1_k127_3739446_2 S-layer homology domain K01183,K01190,K01224,K07407 - 3.2.1.14,3.2.1.22,3.2.1.23,3.2.1.89 0.00002815 49.0
HKD1_k127_3756260_0 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 373.0
HKD1_k127_3756260_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008361 376.0
HKD1_k127_3756260_2 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001841 263.0
HKD1_k127_3756260_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000000000000005199 218.0
HKD1_k127_3756260_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000000002059 172.0
HKD1_k127_3756260_5 DNA replication protein DnaD - - - 0.0000000000000000000000000000000000000000006877 164.0
HKD1_k127_3756260_6 Protein of unknown function (DUF523) - - - 0.0000000000000000000000000000000000000000008309 162.0
HKD1_k127_3756260_7 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000001859 117.0
HKD1_k127_375943_0 Psort location CytoplasmicMembrane, score K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 357.0
HKD1_k127_376571_0 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000002081 190.0
HKD1_k127_376571_1 nitroreductase - - - 0.0000000005207 63.0
HKD1_k127_376851_0 PFAM Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000001733 153.0
HKD1_k127_378064_0 Belongs to the ABC transporter superfamily K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 445.0
HKD1_k127_378064_1 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000003138 237.0
HKD1_k127_3785249_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 516.0
HKD1_k127_3785249_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000004295 156.0
HKD1_k127_3785249_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000002251 83.0
HKD1_k127_3785813_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 301.0
HKD1_k127_3785813_1 RNA-binding protein K06962 - - 0.0000000000000000000000000000000000000000000000000003015 189.0
HKD1_k127_3785813_2 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) K11145 - - 0.000000000000000000000000000000001157 139.0
HKD1_k127_3785813_3 tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 0.000000000000000000007484 94.0
HKD1_k127_3792359_0 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000006264 205.0
HKD1_k127_3792359_1 Membrane-associated phospholipid phosphatase - - - 0.0000000000000000000000000000000000000003329 167.0
HKD1_k127_3800276_0 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 457.0
HKD1_k127_3800276_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 332.0
HKD1_k127_380831_0 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 300.0
HKD1_k127_3823756_0 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 370.0
HKD1_k127_3823756_1 Fructose-1,6-bisphosphatase K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 336.0
HKD1_k127_382470_0 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 431.0
HKD1_k127_382470_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 412.0
HKD1_k127_382470_2 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 288.0
HKD1_k127_3828423_0 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 411.0
HKD1_k127_3831908_0 3-hydroxybutyryl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 402.0
HKD1_k127_3831908_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000005346 152.0
HKD1_k127_3831908_2 Belongs to the UPF0761 family K07058 - - 0.0000000000001769 77.0
HKD1_k127_3832873_0 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 524.0
HKD1_k127_3833410_0 peptidase - - - 2.525e-253 784.0
HKD1_k127_3833410_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain - - - 2.466e-215 672.0
HKD1_k127_3833410_2 4fe-4S ferredoxin, iron-sulfur binding domain protein K12527 - 1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 583.0
HKD1_k127_3848473_0 undecaprenyl K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 338.0
HKD1_k127_3848473_1 HAD hydrolase, family IA, variant K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000004638 207.0
HKD1_k127_38553_0 exonuclease K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 515.0
HKD1_k127_38553_1 FOG Transposase and inactivated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 496.0
HKD1_k127_38553_2 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000000000006334 176.0
HKD1_k127_38553_3 Domain of Unknown Function (DUF1540) - - - 0.00000000000001106 76.0
HKD1_k127_385820_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1016.0
HKD1_k127_3858332_0 Mate efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 290.0
HKD1_k127_3858332_1 - - - - 0.00000000006405 64.0
HKD1_k127_3858332_4 PFAM Resolvase, N-terminal - - - 0.0001273 45.0
HKD1_k127_3863197_0 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 548.0
HKD1_k127_3863197_1 esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 511.0
HKD1_k127_3863197_2 Aminotransferase K00841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 462.0
HKD1_k127_3863197_3 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009669 270.0
HKD1_k127_3863197_4 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000001032 197.0
HKD1_k127_387109_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009611 480.0
HKD1_k127_3890594_0 MATE efflux family protein - - - 4.965e-201 635.0
HKD1_k127_3890594_1 transcriptional regulator - - - 0.00000008907 55.0
HKD1_k127_389643_0 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000002108 211.0
HKD1_k127_389643_1 SH3 type 3 domain protein K01447 - 3.5.1.28 0.0000000000000000000000000000000000000000000000001255 183.0
HKD1_k127_390896_0 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 530.0
HKD1_k127_390896_1 Catalyzes the sodium-dependent transport of glutamate K03312 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 517.0
HKD1_k127_390896_2 Electron transfer flavoprotein K03521 - - 0.000000000000000000001664 94.0
HKD1_k127_3918375_0 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.0000000000000000000000000000000000000000000000000000000000000000184 231.0
HKD1_k127_3918375_1 Holo-ACP synthase CitX K05964 - 2.7.7.61 0.000000000000000000004393 96.0
HKD1_k127_3924311_0 Ser Thr phosphatase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009297 311.0
HKD1_k127_3934480_0 Histidine kinase K07718 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 567.0
HKD1_k127_3934480_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 0.000000000000000000000000000000000000000000006596 169.0
HKD1_k127_3934480_2 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000988 135.0
HKD1_k127_3937754_0 PFAM ATP-binding region K07717 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 338.0
HKD1_k127_3937754_1 YcbB domain K07719 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 295.0
HKD1_k127_3950049_0 Flagellar hook protein FlgE K02390 - - 0.00000000000000000000000000000000000000000000003767 173.0
HKD1_k127_3950049_1 Required for flagellar hook formation. May act as a scaffolding protein K02389 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.000000000000000000000000000181 119.0
HKD1_k127_3950049_2 TIGRFAM flagellar operon protein - - - 0.000000000000000000000003887 106.0
HKD1_k127_3951686_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001155 255.0
HKD1_k127_3951686_1 methanol dehydrogenase K06872 - - 0.0000000000000000000000000000000000000000000000000000000008276 210.0
HKD1_k127_3951686_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000004791 143.0
HKD1_k127_3969724_0 NAD(P)H dehydrogenase (quinone) activity K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.00000000000000000000000000000000000000000000000000000001096 203.0
HKD1_k127_3969724_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000009891 71.0
HKD1_k127_3969724_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000004258 59.0
HKD1_k127_3982507_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 2.55e-199 631.0
HKD1_k127_3991353_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 391.0
HKD1_k127_3991353_1 Belongs to the acetokinase family K00929 - 2.7.2.7 0.000000000000000000000000000000000000000000000005187 175.0
HKD1_k127_3994283_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 385.0
HKD1_k127_3994283_1 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 316.0
HKD1_k127_3994283_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 300.0
HKD1_k127_3994283_3 protein histidine kinase activity - - - 0.0000000000000000000000000000000000001251 145.0
HKD1_k127_3994283_4 - - - - 0.000000000000000000000000001352 128.0
HKD1_k127_3994283_5 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.000000000000000000004757 95.0
HKD1_k127_3994283_6 Protein of unknown function (DUF1232) - - - 0.00000000000000000001865 96.0
HKD1_k127_3998878_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 411.0
HKD1_k127_3998878_1 stage V sporulation protein D K03587,K08384 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000244 200.0
HKD1_k127_3998878_2 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000003998 181.0
HKD1_k127_3998878_3 cell cycle K05589,K12065,K13052 - - 0.0000000005406 66.0
HKD1_k127_400901_0 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 361.0
HKD1_k127_400901_1 Glycosyl hydrolase family 26 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002779 241.0
HKD1_k127_400901_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000003408 204.0
HKD1_k127_4013964_0 Urocanase C-terminal domain K01712 - 4.2.1.49 0.0 1128.0
HKD1_k127_4013964_1 Formiminotransferase domain, N-terminal subdomain K00603 - 2.1.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 427.0
HKD1_k127_4014422_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 325.0
HKD1_k127_4014422_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004566 262.0
HKD1_k127_4014422_2 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000000000002779 228.0
HKD1_k127_4024010_0 Iron only hydrogenase large subunit, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 372.0
HKD1_k127_4024010_1 - - - - 0.000000000002792 68.0
HKD1_k127_402919_0 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 425.0
HKD1_k127_402919_1 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000001049 176.0
HKD1_k127_4032824_0 Cation transporter/ATPase, N-terminus K01537,K01539 - 3.6.3.8,3.6.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 496.0
HKD1_k127_4032824_1 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 323.0
HKD1_k127_403420_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 3.273e-270 843.0
HKD1_k127_403420_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000002655 130.0
HKD1_k127_403420_2 Psort location Cytoplasmic, score 9.98 K00334 - 1.6.5.3 0.00000000000004175 73.0
HKD1_k127_4036664_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 357.0
HKD1_k127_4036664_1 sporulation protein YunB - - - 0.0000000000000000000000000000000000000000000006598 173.0
HKD1_k127_4036664_2 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.000000000004231 69.0
HKD1_k127_4039465_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 307.0
HKD1_k127_4039465_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004801 259.0
HKD1_k127_4045749_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 5.295e-282 898.0
HKD1_k127_4045749_1 stage V sporulation protein K06407 - - 0.0000000000000000000000000000000001971 135.0
HKD1_k127_405224_0 Conserved hypothetical protein 698 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 332.0
HKD1_k127_405224_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 305.0
HKD1_k127_4055724_0 Aconitase family (aconitate hydratase) - - - 3.655e-196 620.0
HKD1_k127_4055724_1 K03540 ribonuclease P protein subunit RPR2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000017 278.0
HKD1_k127_4055724_2 - - - - 0.000000000000000000000284 102.0
HKD1_k127_4066838_0 PFAM Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 556.0
HKD1_k127_4066838_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 495.0
HKD1_k127_4066838_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 329.0
HKD1_k127_4066838_3 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000001613 177.0
HKD1_k127_4066838_4 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000000001348 161.0
HKD1_k127_4066838_5 Cache domain - - - 0.00000000000000000000004845 109.0
HKD1_k127_4069896_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 408.0
HKD1_k127_4069896_1 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 - 2.7.14.1 0.00000000000000000000000000000000000000000000000000000003167 201.0
HKD1_k127_4073087_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 611.0
HKD1_k127_4073087_1 BadF BadG BcrA BcrD - - - 0.0000000000000000000000000000000000000000000000000000000000000004654 229.0
HKD1_k127_4073087_2 Transcriptional Coactivator p15 (PC4) - - - 0.00000000000000000000000000002113 118.0
HKD1_k127_4073087_3 PFAM 4Fe-4S K05337 - - 0.000000000000002162 77.0
HKD1_k127_407715_0 - - - - 0.000000000000000000000000000000001866 140.0
HKD1_k127_407715_1 Thioesterase - - - 0.0000000000008283 71.0
HKD1_k127_4080506_0 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 355.0
HKD1_k127_4080506_1 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000109 280.0
HKD1_k127_4080506_2 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008261 260.0
HKD1_k127_4080506_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000001079 97.0
HKD1_k127_4080760_0 Dehydratase large subunit K01699,K06120 - 4.2.1.28,4.2.1.30 6.39e-295 911.0
HKD1_k127_4080760_1 BMC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 387.0
HKD1_k127_4080760_2 Dehydratase medium subunit K06121,K13919 - 4.2.1.28,4.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 286.0
HKD1_k127_4080760_3 BMC - - - 0.0000000000000000000000000000000000000000000279 162.0
HKD1_k127_4080760_4 Dehydratase small subunit K13920 - 4.2.1.28 0.000000004842 61.0
HKD1_k127_4090855_0 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 354.0
HKD1_k127_4090855_1 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000004985 234.0
HKD1_k127_4090855_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000001373 58.0
HKD1_k127_4091140_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000002751 238.0
HKD1_k127_4091140_1 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000001777 235.0
HKD1_k127_4100271_0 NADH flavin oxidoreductase NADH oxidase K10797 - 1.3.1.31 0.0 1077.0
HKD1_k127_4100271_1 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000002014 191.0
HKD1_k127_4100271_2 EamA-like transporter family - - - 0.00000000000003888 72.0
HKD1_k127_4101404_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 393.0
HKD1_k127_4101404_1 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.00000000000000000000000000000000000000000000000000000000000000000003971 242.0
HKD1_k127_4103741_0 MgtC SapB transporter K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000001352 234.0
HKD1_k127_4103741_1 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02342,K03763 - 2.7.7.7 0.000001015 59.0
HKD1_k127_4112434_0 MutL protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 488.0
HKD1_k127_4112434_1 cobalamin binding K17898 - 5.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 410.0
HKD1_k127_411672_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 9.305e-210 676.0
HKD1_k127_411672_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 564.0
HKD1_k127_411672_2 pur operon repressor K09685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 329.0
HKD1_k127_411672_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000001657 234.0
HKD1_k127_411672_4 Could be involved in septation K06412 - - 0.00000000000000000000000000000000000000003801 153.0
HKD1_k127_411672_5 Psort location CytoplasmicMembrane, score - - - 0.0000000000000051 78.0
HKD1_k127_4133941_0 PFAM transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 334.0
HKD1_k127_4148831_0 AbgT putative transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 331.0
HKD1_k127_4148831_1 AbgT putative transporter family - - - 0.00000000000000000000000000000003736 126.0
HKD1_k127_4148831_2 helix_turn_helix, mercury resistance - - - 0.0003338 46.0
HKD1_k127_415033_0 Binding-protein-dependent transport system inner membrane component K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 400.0
HKD1_k127_4152465_0 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 356.0
HKD1_k127_4152465_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000008242 153.0
HKD1_k127_4172118_0 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000047 259.0
HKD1_k127_4172118_1 NQR2, RnfD, RnfE family K03614 - - 0.00000000000000000000000000000000000000000000000000000001386 201.0
HKD1_k127_4172118_2 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000007151 102.0
HKD1_k127_4172118_3 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000009201 78.0
HKD1_k127_4172938_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008585 266.0
HKD1_k127_4172938_1 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000003882 233.0
HKD1_k127_4179349_0 Fatty acid synthesis protein K21576 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 405.0
HKD1_k127_4179349_1 Membrane-associated sensor domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 347.0
HKD1_k127_4179403_0 Radical_SAM C-terminal domain K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 399.0
HKD1_k127_4179403_1 aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 374.0
HKD1_k127_4179403_2 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000001815 159.0
HKD1_k127_4179403_3 dipeptide transport - - - 0.000000000000000000000214 104.0
HKD1_k127_4200522_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 586.0
HKD1_k127_4200522_1 Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation K01305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 559.0
HKD1_k127_4200522_2 C4-dicarboxylate anaerobic carrier - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 285.0
HKD1_k127_4205152_0 Psort location Cytoplasmic, score 8.87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 296.0
HKD1_k127_4205152_1 Propionate catabolism activator K11914 - - 0.0000000000000000000000000005773 120.0
HKD1_k127_4214793_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 486.0
HKD1_k127_4214793_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 475.0
HKD1_k127_4214793_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 312.0
HKD1_k127_4214793_3 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000311 285.0
HKD1_k127_4214793_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000007429 87.0
HKD1_k127_421527_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006038 267.0
HKD1_k127_421527_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000008405 194.0
HKD1_k127_421527_2 S4 domain protein - - - 0.00000000000000000000000000000000000001344 152.0
HKD1_k127_421527_3 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.00000000000000000000000006387 112.0
HKD1_k127_421527_4 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000001785 70.0
HKD1_k127_421803_0 Belongs to the methyltransferase superfamily K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 475.0
HKD1_k127_421803_1 May be required for sporulation K09762 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 355.0
HKD1_k127_421803_2 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000000000001048 160.0
HKD1_k127_421803_3 peptidylprolyl isomerase K03769,K07533 - 5.2.1.8 0.00000000000000000000000000003103 119.0
HKD1_k127_421803_4 HPr family K11184,K11189 - - 0.000000000000000001425 88.0
HKD1_k127_421803_5 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.0000009454 51.0
HKD1_k127_4227315_0 FtsK/SpoIIIE family K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 301.0
HKD1_k127_4230139_0 iron-sulfur cluster-binding protein K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000004757 255.0
HKD1_k127_4230139_1 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000000001968 113.0
HKD1_k127_4230139_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000003795 88.0
HKD1_k127_4231990_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000004196 227.0
HKD1_k127_424075_0 UPF0313 protein - - - 3.406e-271 845.0
HKD1_k127_424075_1 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate K15024 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000006518 265.0
HKD1_k127_424075_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000006871 263.0
HKD1_k127_424364_0 COG2414 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 6.255e-278 865.0
HKD1_k127_424364_1 Psort location Cytoplasmic, score 9.98 K05796 - - 0.00000000000000000000000000000000000000000000000000002034 192.0
HKD1_k127_424364_2 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000004326 173.0
HKD1_k127_424364_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000001363 130.0
HKD1_k127_424364_4 ThiS family - - - 0.00000000000002869 74.0
HKD1_k127_4248947_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.455e-236 745.0
HKD1_k127_4248947_1 hydrolase, family 3 K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 304.0
HKD1_k127_4248947_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 - - 0.0000000000000000000000000000000000002022 145.0
HKD1_k127_4250465_0 domain protein K06959 - - 2.443e-201 635.0
HKD1_k127_4263750_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 308.0
HKD1_k127_4263750_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000288 264.0
HKD1_k127_4264791_0 C4-dicarboxylate anaerobic carrier - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 499.0
HKD1_k127_4264791_1 amidohydrolase K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 478.0
HKD1_k127_4264791_2 amidohydrolase - - - 0.0000000003382 61.0
HKD1_k127_4274354_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.377e-211 665.0
HKD1_k127_4274354_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 384.0
HKD1_k127_4274354_2 Belongs to the SAICAR synthetase family K01756,K01923 - 4.3.2.2,6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 340.0
HKD1_k127_4274719_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 576.0
HKD1_k127_4274719_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 553.0
HKD1_k127_4274719_10 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.000000000000000000000000000000008493 133.0
HKD1_k127_4274719_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000001822 78.0
HKD1_k127_4274719_12 SNF2 family K08282 - 2.7.11.1 0.00000000001167 72.0
HKD1_k127_4274719_13 Protein of unknown function (DUF3343) - - - 0.0000000003016 63.0
HKD1_k127_4274719_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 430.0
HKD1_k127_4274719_3 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 407.0
HKD1_k127_4274719_4 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 387.0
HKD1_k127_4274719_5 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 332.0
HKD1_k127_4274719_6 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 288.0
HKD1_k127_4274719_7 Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000006951 221.0
HKD1_k127_4274719_8 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000003385 201.0
HKD1_k127_4274719_9 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000001895 200.0
HKD1_k127_4287431_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 4.08e-291 899.0
HKD1_k127_4287431_1 Psort location Cytoplasmic, score K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 354.0
HKD1_k127_4287431_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000000001501 123.0
HKD1_k127_4287431_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00001065 52.0
HKD1_k127_4293472_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000001784 211.0
HKD1_k127_4293472_1 Amidinotransferase - - - 0.000000000000000000000000000000000000003825 147.0
HKD1_k127_4295343_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 454.0
HKD1_k127_4295343_1 Division initiation protein - - - 0.0000000000008281 70.0
HKD1_k127_4295343_2 small basic protein - - - 0.00000000006828 67.0
HKD1_k127_4296391_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 397.0
HKD1_k127_4296391_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000004562 178.0
HKD1_k127_4296391_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000002782 72.0
HKD1_k127_4296411_0 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 507.0
HKD1_k127_4296411_1 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 339.0
HKD1_k127_4300347_0 carboxyltransferase K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 573.0
HKD1_k127_4300347_1 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 334.0
HKD1_k127_4300347_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000231 277.0
HKD1_k127_4300347_3 Uncharacterized protein family UPF0029 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005988 268.0
HKD1_k127_4306835_0 M42 glutamyl aminopeptidase K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 377.0
HKD1_k127_4306835_1 peptidase M42 family protein K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 367.0
HKD1_k127_4306835_2 PFAM UBA THIF-type NAD FAD binding - - - 0.000000000000000000000000000000000000000000000000000000000000000007069 232.0
HKD1_k127_4306835_3 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000002434 130.0
HKD1_k127_4307398_0 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000122 69.0
HKD1_k127_4307398_1 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 0.000000000001324 77.0
HKD1_k127_4307398_2 EDD domain protein, DegV family - - - 0.0000000003386 60.0
HKD1_k127_4314422_0 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000005298 200.0
HKD1_k127_4314422_1 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000005083 122.0
HKD1_k127_4314422_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000002066 82.0
HKD1_k127_4318028_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 336.0
HKD1_k127_4320043_0 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 415.0
HKD1_k127_4323830_0 dehydrogenase complex catalyzes the overall conversion of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 370.0
HKD1_k127_4323830_1 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000691 239.0
HKD1_k127_4323830_2 Belongs to the UPF0371 family - - - 0.00000000000000000000000000000000000000000000000000000000000006178 215.0
HKD1_k127_4323830_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000002118 182.0
HKD1_k127_4324735_0 ABC-type cobalt transport system ATPase component K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 336.0
HKD1_k127_4324735_1 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 331.0
HKD1_k127_4327829_0 exonuclease K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 306.0
HKD1_k127_4328848_0 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003507 260.0
HKD1_k127_4328848_1 PFAM SEC-C motif - - - 0.00000000000000000000000000000000000000000000000000003992 192.0
HKD1_k127_4329379_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000002149 199.0
HKD1_k127_4329379_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000001127 157.0
HKD1_k127_4329379_2 - - - - 0.000000000000000000000000000000000000000001212 156.0
HKD1_k127_4329379_3 Acetyltransferase (GNAT) domain - - - 0.000000000000001908 78.0
HKD1_k127_4332596_0 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 396.0
HKD1_k127_4332596_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001228 247.0
HKD1_k127_4332596_2 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000005494 227.0
HKD1_k127_4334266_0 PFAM Amino acid K03293 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 289.0
HKD1_k127_4334266_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000001313 173.0
HKD1_k127_433732_0 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 549.0
HKD1_k127_433732_1 - - - - 0.0004827 44.0
HKD1_k127_4341937_0 Hydrolase Family 3 K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 341.0
HKD1_k127_4344876_0 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 436.0
HKD1_k127_4344876_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 361.0
HKD1_k127_4344876_2 acetyltransferase K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000006121 229.0
HKD1_k127_4344876_3 FCD domain K05799 - - 0.000000000000000000000000000000000000000000000000000000005416 207.0
HKD1_k127_4344876_4 Major facilitator superfamily - - - 0.00000000004471 68.0
HKD1_k127_4350752_0 PFAM aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 372.0
HKD1_k127_4350752_1 Glycosyl hydrolases family 18 K06306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 367.0
HKD1_k127_4351040_0 Belongs to the D-alanine--D-alanine ligase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 414.0
HKD1_k127_4351040_1 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.00000000000000000002644 90.0
HKD1_k127_4360008_0 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 314.0
HKD1_k127_4360008_1 Domain of unknown function (DUF4364) - - - 0.0000000000000000000000000000000000000000000001207 173.0
HKD1_k127_4360008_2 40-residue YVTN family beta-propeller - - - 0.0000005991 61.0
HKD1_k127_4370896_0 Histidine kinase K07652 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 364.0
HKD1_k127_4370896_1 YycH protein - - - 0.0000000000000000000000000000000001018 147.0
HKD1_k127_4371451_0 Domain of unknown function (DUF2935) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 418.0
HKD1_k127_4371451_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 321.0
HKD1_k127_4371451_2 anion transmembrane transporter activity K02049,K15558 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 303.0
HKD1_k127_4371451_3 Band 7 protein K07192 - - 0.0000000000000000000000000000000000000000000000000000000006362 203.0
HKD1_k127_4371451_4 NMT1-like family K02051 - - 0.0000000000000000000000007301 104.0
HKD1_k127_4376562_0 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K14205 - 2.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 300.0
HKD1_k127_4376562_1 Bacterial PH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001485 225.0
HKD1_k127_4376562_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000885 229.0
HKD1_k127_4376562_3 Hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000175 207.0
HKD1_k127_4376562_4 Cold-shock protein K03704 - - 0.00000000000000000000000000000002777 126.0
HKD1_k127_4376562_5 PFAM cytochrome - - - 0.00000000000000000000000000000008562 130.0
HKD1_k127_4379012_0 phosphoribosylformylglycinamidine synthase K01952 - 6.3.5.3 0.0 1667.0
HKD1_k127_4379012_1 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 5.784e-244 764.0
HKD1_k127_4379012_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000005987 214.0
HKD1_k127_4408010_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 531.0
HKD1_k127_4408010_1 Aromatic amino acid lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 460.0
HKD1_k127_4408010_2 Bacterial regulatory protein, Fis family K06714 - - 0.0000000000000004671 80.0
HKD1_k127_4416772_0 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 429.0
HKD1_k127_4419549_0 PFAM Amino acid K03293 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 528.0
HKD1_k127_4419549_1 Acetyltransferase GNAT family K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000002033 196.0
HKD1_k127_4421888_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009695 249.0
HKD1_k127_4421888_1 PHP domain K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000004773 246.0
HKD1_k127_4421888_2 Cysteine-rich small domain K07162 - - 0.00000000000000000000000000000000000009748 142.0
HKD1_k127_4421888_3 - - - - 0.0000000001466 67.0
HKD1_k127_4421888_4 system, fructose subfamily IIA component K02793 - 2.7.1.191 0.000009607 47.0
HKD1_k127_4422660_0 carbon starvation protein CstA - - - 4.575e-218 683.0
HKD1_k127_4422660_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000009128 119.0
HKD1_k127_4423412_0 inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005459 254.0
HKD1_k127_4423412_1 PFAM ABC transporter related K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000002796 253.0
HKD1_k127_4423412_2 molybdenum cofactor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006855 245.0
HKD1_k127_4423412_3 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000001495 196.0
HKD1_k127_4423412_4 PBP superfamily domain K05772 - - 0.0000000000000000001032 89.0
HKD1_k127_4425207_0 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 539.0
HKD1_k127_4426924_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0 1144.0
HKD1_k127_4426924_1 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 299.0
HKD1_k127_4431745_0 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005228 286.0
HKD1_k127_4431745_1 Belongs to the bacterial flagellin family K02397 - - 0.00000000000000001173 88.0
HKD1_k127_4433740_0 Belongs to the UPF0371 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 424.0
HKD1_k127_4433740_1 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000000000000000000000000000000000005634 191.0
HKD1_k127_4433820_0 AMMECR1 K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 550.0
HKD1_k127_4433820_1 Psort location CytoplasmicMembrane, score K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 310.0
HKD1_k127_4434459_0 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process K07699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 337.0
HKD1_k127_4434459_1 Stage IV sporulation protein B K06399 - 3.4.21.116 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 295.0
HKD1_k127_4434459_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002565 286.0
HKD1_k127_4434459_3 nudix family K01515 - 3.6.1.13 0.00000000000000000000000000000000000001343 146.0
HKD1_k127_4440074_0 Branched-chain amino acid aminotransferase K00826,K02619 - 2.6.1.42,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 577.0
HKD1_k127_4440074_1 Calcium-translocating P-type ATPase, PMCA-type K01537 - 3.6.3.8 0.0000000000000009663 79.0
HKD1_k127_4441275_0 HELICc2 K07464,K10844 - 3.1.12.1,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 327.0
HKD1_k127_4441275_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001328 248.0
HKD1_k127_4441275_2 SMART helicase K07464,K10844 - 3.1.12.1,3.6.4.12 0.0000000000000000000000000000000003122 137.0
HKD1_k127_4441275_3 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000005478 103.0
HKD1_k127_4444288_0 lactate metabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 403.0
HKD1_k127_4444288_1 hydrogenase beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000183 240.0
HKD1_k127_4445310_0 Catalyzes the sodium-dependent transport of glutamate K03312 - - 5.237e-203 638.0
HKD1_k127_4445310_1 HutD - - - 0.0000003526 53.0
HKD1_k127_4445910_0 PFAM Cys Met metabolism K01739,K01760 - 2.5.1.48,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 535.0
HKD1_k127_4445910_1 PFAM Aminotransferase class I and II K14155 - 4.4.1.8 0.000000000000000000001664 94.0
HKD1_k127_4446252_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 519.0
HKD1_k127_4448810_0 Division initiation protein - - - 0.0000000000000000000000000000000000001118 149.0
HKD1_k127_4448810_1 Bacterial protein of unknown function (DUF881) - - - 0.00000000000000000000000002772 112.0
HKD1_k127_4449085_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.613e-229 721.0
HKD1_k127_4451085_0 oligopeptide transporter, OPT family - - - 0.0 1004.0
HKD1_k127_4451085_1 aminoacyl-histidine dipeptidase K01270 - - 6.339e-272 841.0
HKD1_k127_4451085_2 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000000000000000000000000000000004219 174.0
HKD1_k127_4451085_3 - - - - 0.000000000002792 68.0
HKD1_k127_4452557_0 FliG middle domain K02410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 284.0
HKD1_k127_4452557_1 ATP synthase alpha/beta family, beta-barrel domain K02412,K03224 - 3.6.3.14 0.00000000000000000000000000000000000000000005414 165.0
HKD1_k127_4452557_2 Flagellar assembly protein FliH - - - 0.0000000000000000000000005693 114.0
HKD1_k127_4458581_0 Polysaccharide deacetylase K01567,K22278 GO:0005575,GO:0016020 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 368.0
HKD1_k127_4458581_1 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000000003531 226.0
HKD1_k127_4458581_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000001436 106.0
HKD1_k127_4460694_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001082 256.0
HKD1_k127_4460694_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000009881 218.0
HKD1_k127_4460694_2 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000000009582 111.0
HKD1_k127_4460694_3 Psort location Cytoplasmic, score - - - 0.00000000000000002255 84.0
HKD1_k127_4475361_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 417.0
HKD1_k127_4475415_0 Carbon starvation protein K06200 - - 2.954e-197 626.0
HKD1_k127_4475415_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 312.0
HKD1_k127_4475415_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K18330,K22340 - 1.12.1.3,1.17.1.11,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000009594 228.0
HKD1_k127_4475415_3 Cold shock protein K03704 - - 0.00000000000000000000000000000001054 127.0
HKD1_k127_4478514_0 O-acetylhomoserine K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 581.0
HKD1_k127_4478514_1 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000003504 227.0
HKD1_k127_4478514_2 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000000000000000000000000000000001892 191.0
HKD1_k127_4479117_0 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 389.0
HKD1_k127_4479117_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006778 274.0
HKD1_k127_4479435_0 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 369.0
HKD1_k127_4479435_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000005199 218.0
HKD1_k127_4479435_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000002745 203.0
HKD1_k127_4482027_0 Transposase domain (DUF772) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 578.0
HKD1_k127_4487921_0 magnesium chelatase K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 342.0
HKD1_k127_4487921_1 magnesium chelatase K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 332.0
HKD1_k127_4487921_2 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003642 252.0
HKD1_k127_4487921_3 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001775 244.0
HKD1_k127_449401_0 Bacterial regulatory protein, Fis family K06714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 461.0
HKD1_k127_4504140_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 434.0
HKD1_k127_4504140_1 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 373.0
HKD1_k127_4504140_2 PFAM response regulator receiver K02483 - - 0.000000000000000000000000000000000000000000001432 166.0
HKD1_k127_4504140_3 inner membrane component K05773 - - 0.000000000000000000000000000002958 122.0
HKD1_k127_4504679_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.009e-222 699.0
HKD1_k127_4504679_1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 582.0
HKD1_k127_4504679_2 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 517.0
HKD1_k127_4504679_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 411.0
HKD1_k127_4504679_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 318.0
HKD1_k127_4504679_5 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001969 160.0
HKD1_k127_4504679_6 Predicted membrane protein (DUF2232) - - - 0.000000000000000000000000001854 124.0
HKD1_k127_4504679_7 LysM domain - - - 0.0000000000000002032 86.0
HKD1_k127_4515843_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000001327 159.0
HKD1_k127_4532625_0 Initiates the rapid degradation of small, acid-soluble proteins during spore germination K06012 - 3.4.24.78 0.00000000000000000000000000000000000000000000000000000000000000000000002962 250.0
HKD1_k127_4532625_1 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000008831 106.0
HKD1_k127_4538515_0 helicase K07464,K10844 - 3.1.12.1,3.6.4.12 0.000000000000000000000000000000000000000000000000009765 186.0
HKD1_k127_4538515_1 Aminotransferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000004431 147.0
HKD1_k127_4541952_0 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008323 282.0
HKD1_k127_4541952_1 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000001241 161.0
HKD1_k127_4541952_2 Na+/H+ antiporter family - - - 0.0000000000000000000000000001579 123.0
HKD1_k127_4567934_0 Cytidylyltransferase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 534.0
HKD1_k127_4575770_0 gluconate H symporter K03299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 564.0
HKD1_k127_4575770_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000002199 151.0
HKD1_k127_4575770_2 PFAM FGGY family of carbohydrate kinases, N-terminal domain K00854,K11216 - 2.7.1.17,2.7.1.189 0.0000003758 55.0
HKD1_k127_4582047_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 412.0
HKD1_k127_4582047_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 325.0
HKD1_k127_4582047_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000009175 244.0
HKD1_k127_4582047_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000001843 152.0
HKD1_k127_458460_0 Protein of unknown function (DUF4003) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 349.0
HKD1_k127_458460_1 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000000000000000000000001143 203.0
HKD1_k127_4584678_0 binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007931 263.0
HKD1_k127_4589611_0 Family 5 K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 587.0
HKD1_k127_4589611_1 Psort location CytoplasmicMembrane, score K10823 - - 0.00000000000000000000000000000000000000000000000000000000000002334 216.0
HKD1_k127_4589611_2 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000827 66.0
HKD1_k127_4592923_0 Hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 448.0
HKD1_k127_4592923_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000007593 192.0
HKD1_k127_4599174_0 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 419.0
HKD1_k127_4599174_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000002224 116.0
HKD1_k127_4605283_0 stage V sporulation protein D K03587,K08384 - 3.4.16.4 3.18e-215 687.0
HKD1_k127_4619829_0 ATPase. Has a role at an early stage in the morphogenesis of the spore coat K06398 GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 481.0
HKD1_k127_4619829_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00001926 51.0
HKD1_k127_4626480_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 413.0
HKD1_k127_4632231_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 503.0
HKD1_k127_4632231_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000000000000000531 85.0
HKD1_k127_4635942_0 amino acid K03758 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 472.0
HKD1_k127_4635942_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000002803 59.0
HKD1_k127_4642655_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000006644 191.0
HKD1_k127_4642655_1 Acyltransferase family - - - 0.0000000000000000000000000000000000000000001968 172.0
HKD1_k127_4642655_2 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000002426 93.0
HKD1_k127_4650519_0 Six-Cys-in-45 modification radical SAM protein K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 388.0
HKD1_k127_4650519_1 six-cysteine peptide SCIFF - - - 0.0000000000002116 70.0
HKD1_k127_4657876_0 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 496.0
HKD1_k127_4657876_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 428.0
HKD1_k127_4657876_2 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 315.0
HKD1_k127_4662796_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000551 271.0
HKD1_k127_4662796_1 Domain of unknown function (DUF1893) - - - 0.000000000000000000004043 94.0
HKD1_k127_4663855_0 PFAM acetate and butyrate kinase K00929 - 2.7.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 454.0
HKD1_k127_4663855_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 459.0
HKD1_k127_4670859_0 Stage V sporulation protein B K06409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006237 341.0
HKD1_k127_4670859_1 aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 313.0
HKD1_k127_4673317_0 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000003548 197.0
HKD1_k127_4673317_1 - - - - 0.000000000000000000000000000000000000000008357 158.0
HKD1_k127_4677098_0 maturation GTPase HydF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 592.0
HKD1_k127_4677098_1 TIGRFAM glutamate synthases, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 501.0
HKD1_k127_4677098_2 biosynthesis protein ThiH K03150 - 4.1.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 345.0
HKD1_k127_4681038_0 malic enzyme K00027 - 1.1.1.38 5.676e-210 655.0
HKD1_k127_4681038_1 2-keto-3-deoxygluconate permease K02526 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 531.0
HKD1_k127_4688466_0 protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain - - - 0.0000000000000000000000000000000000000000000000001503 188.0
HKD1_k127_4688466_1 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000006681 118.0
HKD1_k127_4688538_0 Domain of unknown function (DUF362) K07138 - - 3.998e-194 609.0
HKD1_k127_4688538_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000004945 216.0
HKD1_k127_4688538_2 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000009111 160.0
HKD1_k127_4691223_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 3.692e-236 739.0
HKD1_k127_4691223_1 TIM barrel - - - 0.00000000000000000000000000000000000000001658 156.0
HKD1_k127_4693646_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 601.0
HKD1_k127_4693646_1 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 601.0
HKD1_k127_4693646_2 ANTAR domain protein K22010 - - 0.00000000000000000000000000000000000000000000000000000000002806 211.0
HKD1_k127_4693646_3 PFAM Glutamine synthetase, catalytic K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000001696 172.0
HKD1_k127_4693646_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000002238 53.0
HKD1_k127_4693815_0 helicase K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 449.0
HKD1_k127_4693815_1 PFAM Rubrerythrin - - - 0.00000000000000005488 84.0
HKD1_k127_4697007_0 Cache 3/Cache 2 fusion domain - - - 3.07e-201 644.0
HKD1_k127_4697007_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 500.0
HKD1_k127_4697007_2 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 402.0
HKD1_k127_4697007_3 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 381.0
HKD1_k127_4697007_4 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 378.0
HKD1_k127_4697007_5 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 322.0
HKD1_k127_4697007_6 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000005982 102.0
HKD1_k127_4698851_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 582.0
HKD1_k127_4698851_1 CbiG protein K02189 - 3.7.1.12 0.00000000000000000000001151 104.0
HKD1_k127_471069_0 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 464.0
HKD1_k127_471069_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000003392 171.0
HKD1_k127_4712780_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K05565,K14086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 501.0
HKD1_k127_4712780_1 NADH dehydrogenase K00337,K14087 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 443.0
HKD1_k127_4712780_2 NADH ubiquinone oxidoreductase K00331,K14088 - 1.6.5.3 0.00000000000000000000000000000000000000000001074 162.0
HKD1_k127_4721466_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 467.0
HKD1_k127_4721466_1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000003363 248.0
HKD1_k127_4721967_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 405.0
HKD1_k127_4721967_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 337.0
HKD1_k127_4721967_2 hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002975 279.0
HKD1_k127_4721967_3 Homoserine dehydrogenase - - - 0.000000000000000000004312 93.0
HKD1_k127_4725938_0 Molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 356.0
HKD1_k127_4725938_1 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.000000000000000000009778 94.0
HKD1_k127_4726511_0 PFAM Manganese containing catalase K06334 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 353.0
HKD1_k127_4726511_1 EDD domain protein, DegV family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 288.0
HKD1_k127_4726511_2 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000000205 202.0
HKD1_k127_4726511_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000003563 199.0
HKD1_k127_4726511_6 Spore coat associated protein JA (CotJA) - - - 0.00000000000000000000002654 100.0
HKD1_k127_4726511_7 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000001192 95.0
HKD1_k127_4728609_0 basic membrane K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 440.0
HKD1_k127_4728609_1 Purine nucleoside phosphorylase K03784 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 421.0
HKD1_k127_4729518_0 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000003532 146.0
HKD1_k127_4732194_0 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000054 220.0
HKD1_k127_4732194_1 Domain of unknown function (DUF378) K09779 - - 0.00000000000274 68.0
HKD1_k127_4732194_2 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00003538 47.0
HKD1_k127_4736668_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 449.0
HKD1_k127_4736668_1 DNA polymerase K02337,K14162 - 2.7.7.7 0.000000000000000000000000003956 119.0
HKD1_k127_4747661_0 M18 family aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 539.0
HKD1_k127_4752004_0 methyl-accepting chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 403.0
HKD1_k127_4752004_1 methyl-accepting chemotaxis protein K03406 - - 0.0000000006779 64.0
HKD1_k127_4754191_0 ABC transporter, ATP-binding protein K16960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 355.0
HKD1_k127_4754191_1 Bacterial periplasmic substrate-binding proteins K16957 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005545 274.0
HKD1_k127_4754849_0 Belongs to the UPF0348 family - - - 0.000000000000000000000000000000000000000000004438 169.0
HKD1_k127_4754849_1 - - - - 0.00000000000000000000000000000000000000002012 157.0
HKD1_k127_4755180_0 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 544.0
HKD1_k127_4755180_1 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 316.0
HKD1_k127_4755180_2 GntR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000659 255.0
HKD1_k127_4755180_3 PFAM Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase K05964 - 2.7.7.61 0.0000000000000000000006067 99.0
HKD1_k127_4755180_4 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.000008409 48.0
HKD1_k127_4755464_0 PFAM Appr-1-p processing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 430.0
HKD1_k127_4755464_1 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 293.0
HKD1_k127_4760395_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 2.149e-204 642.0
HKD1_k127_4760452_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 310.0
HKD1_k127_4760452_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000002498 162.0
HKD1_k127_4761824_0 Putative nucleotide-binding of sugar-metabolising enzyme K22129 - 2.7.1.219,2.7.1.220 9.042e-201 633.0
HKD1_k127_4761824_1 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 557.0
HKD1_k127_4761824_2 GntP family permease K03299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 407.0
HKD1_k127_4761824_3 PFAM Sporulation and spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 350.0
HKD1_k127_4761824_4 transcriptional regulator DeoR family K02081,K03436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 332.0
HKD1_k127_4761824_5 FCD - - - 0.0000000000000000000000000000000000000000000000000000000002263 209.0
HKD1_k127_4762570_0 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009615 501.0
HKD1_k127_4762570_1 S1, RNA binding domain K00243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 309.0
HKD1_k127_4763605_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 441.0
HKD1_k127_4763605_1 PRC-barrel domain - - - 0.000000004361 60.0
HKD1_k127_4764387_0 PFAM peptidase S11, D-alanyl-D-alanine carboxypeptidase K07258 - 3.4.16.4 0.00000000000000001157 86.0
HKD1_k127_4764387_1 Sporulation protein YtfJ - - - 0.00006586 51.0
HKD1_k127_4767071_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 3.206e-263 820.0
HKD1_k127_4767071_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 294.0
HKD1_k127_4767071_2 Protein of unknown function (DUF3006) - - - 0.000000000000000006146 85.0
HKD1_k127_4767071_3 Metallo-beta-lactamase domain protein K02238 - - 0.0000000000000003992 79.0
HKD1_k127_4768203_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006023 230.0
HKD1_k127_4768203_1 Na driven multidrug efflux pump - - - 0.000000000000001207 79.0
HKD1_k127_4768203_2 Na driven multidrug efflux pump - - - 0.0000000001802 63.0
HKD1_k127_4772216_0 aminoacyl-histidine dipeptidase K01270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 484.0
HKD1_k127_4772216_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000007899 194.0
HKD1_k127_4775195_0 ABC transporter transmembrane region K06147 - - 1.651e-200 631.0
HKD1_k127_477619_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 2.576e-257 800.0
HKD1_k127_477619_1 peptidoglycan binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 447.0
HKD1_k127_477619_2 Biotin carboxyl carrier protein - - - 0.0000000000000000000000000000000002777 136.0
HKD1_k127_477619_3 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000007444 119.0
HKD1_k127_477619_4 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000003327 117.0
HKD1_k127_477619_7 - - - - 0.00009517 52.0
HKD1_k127_4779763_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 417.0
HKD1_k127_4779763_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000007444 233.0
HKD1_k127_4780167_0 ribonuclease, Rne Rng family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 331.0
HKD1_k127_4782589_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 450.0
HKD1_k127_4782589_1 Periplasmic binding protein K02016 - - 0.000000000000006439 76.0
HKD1_k127_4782589_2 PFAM IstB domain protein ATP-binding protein - - - 0.0005311 42.0
HKD1_k127_4786252_0 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA) K03429 GO:0003674,GO:0003824,GO:0008194,GO:0016740,GO:0016757,GO:0016758,GO:0035251,GO:0046527,GO:0047228 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 336.0
HKD1_k127_4786252_1 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000001113 129.0
HKD1_k127_4786252_2 Sigma-54 interaction domain - - - 0.0000006677 52.0
HKD1_k127_4786883_0 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000005873 202.0
HKD1_k127_4786883_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000302 76.0
HKD1_k127_4786883_2 Belongs to the pirin family K06911 - - 0.00000000001025 65.0
HKD1_k127_4787167_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 359.0
HKD1_k127_4787167_1 TIGRFAM competence protein ComEA helix-hairpin-helix K02237 - - 0.00000000000003838 78.0
HKD1_k127_4792720_0 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000004974 211.0
HKD1_k127_4792720_1 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000626 126.0
HKD1_k127_4792720_2 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000004207 49.0
HKD1_k127_4793220_0 Permease K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 344.0
HKD1_k127_4793220_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000003666 183.0
HKD1_k127_4794439_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 297.0
HKD1_k127_4794439_1 thiamine pyrophosphokinase K00949 - 2.7.6.2 0.0000000000000000000000000000000000000000000000000003465 191.0
HKD1_k127_4794439_2 Asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.00000000000000000000000003246 110.0
HKD1_k127_4794439_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000001039 99.0
HKD1_k127_4813779_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 7.41e-289 897.0
HKD1_k127_4836957_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 388.0
HKD1_k127_4836957_1 HhH-GPD superfamily base excision DNA repair protein K00567,K01247 - 2.1.1.63,3.2.2.21 0.000000000000000000000000000000000000000144 153.0
HKD1_k127_4849016_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.367e-278 870.0
HKD1_k127_4859090_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.495e-289 913.0
HKD1_k127_4859090_1 Class II release factor RF3, C-terminal domain K02837 - - 7.073e-273 846.0
HKD1_k127_4859090_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 601.0
HKD1_k127_4859090_3 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 561.0
HKD1_k127_4859090_4 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 438.0
HKD1_k127_4859090_5 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 411.0
HKD1_k127_4859090_6 BadF BadG BcrA BcrD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
HKD1_k127_4859090_7 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000004609 151.0
HKD1_k127_4869756_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 472.0
HKD1_k127_4869756_1 Psort location Cytoplasmic, score 8.87 K10672 - 1.21.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002076 260.0
HKD1_k127_4869756_2 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672,K21579 - 1.21.4.2,1.21.4.4 0.0000000000000000000000000000000000000005865 149.0
HKD1_k127_4872609_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 551.0
HKD1_k127_4873643_0 Belongs to the nlpA lipoprotein family K02073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001387 280.0
HKD1_k127_4873643_1 FCD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001223 249.0
HKD1_k127_487697_0 phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 289.0
HKD1_k127_487697_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
HKD1_k127_487697_2 phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000004459 228.0
HKD1_k127_489566_0 metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 527.0
HKD1_k127_489566_1 Sigma54 specific transcriptional regulator, Fis family K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005084 279.0
HKD1_k127_490405_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 5.883e-197 621.0
HKD1_k127_490405_1 Folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000003612 88.0
HKD1_k127_490405_2 Helix-turn-helix diphteria tox regulatory element - - - 0.00000000000000001407 83.0
HKD1_k127_490405_3 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.00002976 46.0
HKD1_k127_4913454_0 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 301.0
HKD1_k127_4913454_1 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003501 244.0
HKD1_k127_4913688_0 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 506.0
HKD1_k127_4913688_1 Psort location CytoplasmicMembrane, score 10.00 K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 442.0
HKD1_k127_4913688_2 Psort location CytoplasmicMembrane, score K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 372.0
HKD1_k127_4920224_0 Transglutaminase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001462 251.0
HKD1_k127_4920224_1 twitching motility protein K02669 - - 0.0000000000000000000003872 97.0
HKD1_k127_4920253_0 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 523.0
HKD1_k127_4920253_1 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002735 260.0
HKD1_k127_4920253_2 PFAM cobalamin B12-binding domain protein - - - 0.000000000000000000000000000000009744 128.0
HKD1_k127_4931476_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 535.0
HKD1_k127_4931476_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003095 227.0
HKD1_k127_4931476_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0001073 46.0
HKD1_k127_4935325_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 474.0
HKD1_k127_4935325_1 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 450.0
HKD1_k127_4935325_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000003575 207.0
HKD1_k127_4935325_3 sporulation protein, YlmC YmxH - - - 0.0000000000000001643 81.0
HKD1_k127_4953903_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000007389 141.0
HKD1_k127_4957845_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 296.0
HKD1_k127_4957845_1 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.000000000000000000000000000000000000000000000000000000000808 205.0
HKD1_k127_4963958_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 535.0
HKD1_k127_4965780_0 MutL protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 442.0
HKD1_k127_4965780_1 Catalyzes the carbon skeleton rearrangement of L- glutamate to L-threo-3-methylaspartate ((2S,3S)-3- methylaspartate) K01846 - 5.4.99.1 0.0000000000000000001589 88.0
HKD1_k127_4965877_0 Orn Lys Arg decarboxylase major K01582 - 4.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 403.0
HKD1_k127_4965877_1 Fusaric acid resistance protein-like - - - 0.0000000000000000000000000000000001451 140.0
HKD1_k127_4965877_2 TSCPD domain - - - 0.000000000000000000000000005453 111.0
HKD1_k127_4965877_3 Sigma-K factor-processing regulatory protein BofA K06317 - - 0.0000001917 56.0
HKD1_k127_4966058_0 NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 471.0
HKD1_k127_4966058_1 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 303.0
HKD1_k127_4966058_2 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000001417 194.0
HKD1_k127_4966168_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 496.0
HKD1_k127_4966168_1 Thymidine kinase K00857 - 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000005826 260.0
HKD1_k127_4966874_0 Belongs to the peptidase S16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002233 252.0
HKD1_k127_4968253_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008536 249.0
HKD1_k127_4970347_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 434.0
HKD1_k127_4974264_0 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.00000000000000000000000000000000000000000000000000003114 194.0
HKD1_k127_4974264_1 FCD - - - 0.00000000000000000000000000000000000000000000000000009323 191.0
HKD1_k127_4974514_0 Abc transporter K06158 - - 3.521e-199 625.0
HKD1_k127_4974514_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 392.0
HKD1_k127_4975216_0 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000002674 242.0
HKD1_k127_4975216_1 malic enzyme K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000005545 218.0
HKD1_k127_4977450_0 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 307.0
HKD1_k127_4977450_1 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.000000000000000000000000000000000001358 142.0
HKD1_k127_4977450_2 Cupin domain-containing protein - - - 0.0000000000000000000000000000000007301 133.0
HKD1_k127_4979109_0 extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 464.0
HKD1_k127_4979109_1 ABC transporter K02028 - 3.6.3.21 0.0000000000000000000000000000000000000001236 151.0
HKD1_k127_4979769_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 365.0
HKD1_k127_4979769_1 carbohydrate transport K21395 - - 0.000000000000000000000000000000000000000000002568 170.0
HKD1_k127_4981861_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 396.0
HKD1_k127_4983508_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 542.0
HKD1_k127_4988422_0 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 336.0
HKD1_k127_4988422_1 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000001919 202.0
HKD1_k127_5004190_0 Putative amidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 516.0
HKD1_k127_5006500_0 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 464.0
HKD1_k127_5006500_1 PFAM periplasmic binding protein K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 394.0
HKD1_k127_5006500_2 import. Responsible for energy coupling to the transport system K10441,K10542 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 341.0
HKD1_k127_5006500_3 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 338.0
HKD1_k127_5014408_0 Permease family K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 459.0
HKD1_k127_5021984_0 transcriptional regulator K03721 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 331.0
HKD1_k127_5021984_1 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding - - - 0.0000000000000000000000000000000000000000000000000000001111 207.0
HKD1_k127_5028158_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 3.238e-308 952.0
HKD1_k127_5028158_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000003999 146.0
HKD1_k127_5029383_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.0 1238.0
HKD1_k127_5029640_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000003966 234.0
HKD1_k127_5029640_1 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000001903 131.0
HKD1_k127_5036886_0 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000003362 188.0
HKD1_k127_5036886_1 bacterial-type flagellum-dependent cell motility K02387,K02388 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009425,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.0000000000000000000000001234 110.0
HKD1_k127_5041251_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 419.0
HKD1_k127_5041251_1 stage II sporulation protein P K06385 - - 0.000000000000000000000000000000000000000000002787 179.0
HKD1_k127_5041357_0 S-layer homology domain - - - 0.000000000000000000000002605 119.0
HKD1_k127_5041357_1 WG containing repeat - - - 0.00000000000000000005161 105.0
HKD1_k127_5043675_0 MazG family K02428,K02499 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 487.0
HKD1_k127_5043675_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000004728 147.0
HKD1_k127_5044114_0 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 513.0
HKD1_k127_5044114_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002009 275.0
HKD1_k127_5047787_0 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 472.0
HKD1_k127_5047787_1 Oligopeptide/dipeptide transporter, C-terminal region K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 468.0
HKD1_k127_5047787_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 300.0
HKD1_k127_5047787_3 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.00000000000000000000000000000000001886 138.0
HKD1_k127_5068121_0 Cytidylyltransferase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 539.0
HKD1_k127_5073074_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001542 235.0
HKD1_k127_5073074_1 Ion channel K10716 - - 0.0005135 50.0
HKD1_k127_5079758_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 459.0
HKD1_k127_5079758_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704,K20453 - 4.2.1.33,4.2.1.35,4.2.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000005303 254.0
HKD1_k127_5079758_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000002142 68.0
HKD1_k127_5087366_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 574.0
HKD1_k127_5087366_1 Phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000003986 141.0
HKD1_k127_5087366_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000002957 132.0
HKD1_k127_5092014_0 Aminotransferase class I and II K00832 - 2.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 588.0
HKD1_k127_5092014_1 Cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 522.0
HKD1_k127_5092014_2 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 497.0
HKD1_k127_5092014_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 426.0
HKD1_k127_5092014_4 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 353.0
HKD1_k127_5092014_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006218 255.0
HKD1_k127_5092014_6 MatE - - - 0.0000000000000000004349 89.0
HKD1_k127_5097759_0 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 504.0
HKD1_k127_5097759_1 hmm pf00294 K00852,K16328 - 2.7.1.15,2.7.1.83 0.00000000000000000000000000000000003384 138.0
HKD1_k127_5103704_0 PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 299.0
HKD1_k127_5107684_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000004589 166.0
HKD1_k127_5107684_1 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000006459 135.0
HKD1_k127_5107684_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000002863 115.0
HKD1_k127_5107684_3 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000003918 116.0
HKD1_k127_5107684_4 response regulator, receiver K03413 - - 0.0000001789 52.0
HKD1_k127_5107937_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 474.0
HKD1_k127_5107937_1 Zinc carboxypeptidase K01308 - 3.4.19.11 0.0000000000000000006668 95.0
HKD1_k127_5110402_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.067e-226 707.0
HKD1_k127_5110402_1 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 373.0
HKD1_k127_5110402_2 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 306.0
HKD1_k127_5110402_3 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 288.0
HKD1_k127_5110402_4 Peptidase, M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001452 276.0
HKD1_k127_5110402_5 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000005725 233.0
HKD1_k127_5110402_6 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000003703 227.0
HKD1_k127_5110402_7 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000008563 189.0
HKD1_k127_5110402_8 Mazg nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000000000000000000005382 160.0
HKD1_k127_5110402_9 PrcB C-terminal - - - 0.00000000000000000000000000000000000214 143.0
HKD1_k127_5116962_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K21577 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 502.0
HKD1_k127_5116962_1 In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.000000000000000000000000000000000000000000000000000001233 192.0
HKD1_k127_5116962_2 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000001337 181.0
HKD1_k127_5116962_3 Glycine sarcosine betaine reductase complex K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0000000000000001268 79.0
HKD1_k127_5117941_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.126e-204 645.0
HKD1_k127_5117941_1 domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000004799 246.0
HKD1_k127_5117941_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000007148 243.0
HKD1_k127_5117941_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000001698 128.0
HKD1_k127_5117941_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000006157 55.0
HKD1_k127_5119028_0 Bacterial regulatory protein, Fis family K06714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 531.0
HKD1_k127_5119028_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000001619 242.0
HKD1_k127_5119028_2 Stage II sporulation protein R (spore_II_R) K06387 - - 0.0000000000000000000000000000000000000004583 157.0
HKD1_k127_5119028_3 Domain of unknown function (DUF1934) - - - 0.00000000003281 69.0
HKD1_k127_5120067_0 Methylmalonyl-CoA mutase - - - 1.311e-230 724.0
HKD1_k127_5120067_1 PFAM cobalamin B12-binding domain protein - - - 0.00000000000000000000000000000000000000000000005289 171.0
HKD1_k127_5120067_2 PFAM sigma-54 factor interaction domain-containing protein, Propionate catabolism activator domain-containing protein - - - 0.00000000000000000000000000000000000000000002861 168.0
HKD1_k127_5122275_0 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 461.0
HKD1_k127_5124291_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000001023 259.0
HKD1_k127_5124291_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000002984 195.0
HKD1_k127_5124291_2 nitroreductase - - - 0.000000000000000000000000000000000000000000000000004271 186.0
HKD1_k127_5124291_3 Psort location Cytoplasmic, score 9.97 K00248 - 1.3.8.1 0.0001475 44.0
HKD1_k127_5124525_0 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 575.0
HKD1_k127_5124525_1 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 424.0
HKD1_k127_5124525_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 384.0
HKD1_k127_5124525_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 296.0
HKD1_k127_5124525_4 NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002516 270.0
HKD1_k127_5124525_5 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002829 263.0
HKD1_k127_5124525_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000001974 106.0
HKD1_k127_5128966_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 318.0
HKD1_k127_5128966_1 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000003721 214.0
HKD1_k127_5128966_2 SMART Glycoside hydrolase, family 10 K01181 - 3.2.1.8 0.0000007562 61.0
HKD1_k127_51332_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 441.0
HKD1_k127_5137803_0 ATP-dependent helicase deoxyribonuclease subunit B K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 375.0
HKD1_k127_5137803_1 domain protein K03698 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 341.0
HKD1_k127_5137803_2 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000000000001788 152.0
HKD1_k127_5139_0 Protein of unknown function (DUF819) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 479.0
HKD1_k127_5139_1 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 433.0
HKD1_k127_5144004_0 TIGRFAM citrate H symporter, CitMHS family K03300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 574.0
HKD1_k127_5144004_1 Acyclic terpene utilisation family protein AtuA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 300.0
HKD1_k127_5147200_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 291.0
HKD1_k127_5147200_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000003305 77.0
HKD1_k127_5161477_0 histidine kinase HAMP region domain protein K07651,K07652 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 447.0
HKD1_k127_5161477_1 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 380.0
HKD1_k127_5161477_2 Protein of unknown function (DUF2680) - - - 0.000000000000000000000000000000000001004 143.0
HKD1_k127_5168675_0 PFAM extracellular solute-binding protein, family 5 K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 494.0
HKD1_k127_5168675_1 RNA polymerase sigma54 factor K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 428.0
HKD1_k127_5168675_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 397.0
HKD1_k127_5170864_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 565.0
HKD1_k127_5170864_1 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01034 - 2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 303.0
HKD1_k127_5170864_2 3-oxoacid CoA-transferase, B subunit K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000002349 147.0
HKD1_k127_5173617_0 AMP-binding enzyme C-terminal domain - - - 3.991e-280 870.0
HKD1_k127_5173617_1 pentaerythritol trinitrate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 523.0
HKD1_k127_5173617_2 2-keto-3-deoxygluconate permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 308.0
HKD1_k127_5173617_3 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.0005692 43.0
HKD1_k127_5174121_0 Psort location CytoplasmicMembrane, score 9.97 K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000002936 233.0
HKD1_k127_5174121_1 - - - - 0.0000000000000000387 84.0
HKD1_k127_5174121_2 Family of unknown function (DUF5317) - - - 0.0000000009505 67.0
HKD1_k127_5175615_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 473.0
HKD1_k127_5175615_1 Mo-molybdopterin cofactor biosynthetic process - - - 0.0000005189 53.0
HKD1_k127_5181598_0 - - - - 0.00000000000000000000000000000000000004365 150.0
HKD1_k127_5181598_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000012 89.0
HKD1_k127_5185530_0 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 566.0
HKD1_k127_5185530_1 Elongation factor G C-terminus K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 447.0
HKD1_k127_5185530_2 Bacterial transcription activator, effector binding domain - - - 0.00000000000000000000000000000000000000000000000008867 182.0
HKD1_k127_5185530_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000001785 112.0
HKD1_k127_5193858_0 Glycosyltransferase, group 1 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 464.0
HKD1_k127_5193858_1 Psort location Cytoplasmic, score 8.87 - - - 0.0006524 42.0
HKD1_k127_5198599_0 Psort location Cytoplasmic, score K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 445.0
HKD1_k127_5198599_1 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000001411 160.0
HKD1_k127_5198599_2 RNA pseudouridylate synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000001116 119.0
HKD1_k127_5198716_0 Binding-protein-dependent transport system inner membrane component K10037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 299.0
HKD1_k127_5198716_1 COG COG1126 ABC-type polar amino acid transport system, ATPase component K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 287.0
HKD1_k127_5198716_2 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000001839 240.0
HKD1_k127_52028_0 Domain of unknown function (DUF1858) - - - 0.0000000000000000001575 89.0
HKD1_k127_5219730_0 Collagenase K08303 - - 2.377e-195 611.0
HKD1_k127_5219730_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 489.0
HKD1_k127_5219812_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 305.0
HKD1_k127_5219812_1 Abc transporter K15738 - - 0.0000000000000000000000000000000000000000000000000000000000001079 216.0
HKD1_k127_5219812_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000002258 120.0
HKD1_k127_5222205_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.876e-204 642.0
HKD1_k127_5222205_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 409.0
HKD1_k127_5222205_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 332.0
HKD1_k127_5222205_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000001474 220.0
HKD1_k127_5222205_4 FMN binding - - - 0.000000000000000000000000000000000000000000000002402 175.0
HKD1_k127_5222205_5 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000002217 173.0
HKD1_k127_5222205_6 FMN binding - - - 0.000000000001958 66.0
HKD1_k127_5227169_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03169 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 368.0
HKD1_k127_5227169_1 - - - - 0.000001311 56.0
HKD1_k127_5228074_0 Hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 348.0
HKD1_k127_5228074_1 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.0000000000000000000000000000000001836 134.0
HKD1_k127_5228074_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000003162 95.0
HKD1_k127_5232048_0 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 429.0
HKD1_k127_5232048_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000001624 115.0
HKD1_k127_5241230_0 TIGRFAM cysteine desulfurase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 483.0
HKD1_k127_5241230_1 MATE efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 440.0
HKD1_k127_5241230_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 324.0
HKD1_k127_5241230_3 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000000000000000000000000001814 191.0
HKD1_k127_5241230_4 Bacterial protein of unknown function (DUF951) - - - 0.000000000000000000005042 94.0
HKD1_k127_5241230_5 Colicin V production protein K03558 - - 0.0000000000000007399 86.0
HKD1_k127_5241230_6 - - - - 0.000000001408 69.0
HKD1_k127_5248783_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 424.0
HKD1_k127_5248783_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401,K03229,K04061,K13820,K22510 - - 0.0000000000000000000000000000000000000000000000000005252 186.0
HKD1_k127_5251055_0 Major Facilitator K08151,K08153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002551 281.0
HKD1_k127_5251055_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000005497 253.0
HKD1_k127_5251055_2 Sigma factor PP2C-like phosphatases K06382 - 3.1.3.16 0.0000000000000000000000000000002199 141.0
HKD1_k127_5251055_3 Sporulation protein YabP - - - 0.0000000000000001225 83.0
HKD1_k127_5251055_4 Septum formation initiator K13052 - - 0.0000000000000105 81.0
HKD1_k127_5251055_5 Spore cortex biosynthesis protein YabQ - - - 0.0000000000001349 78.0
HKD1_k127_5252792_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K15580 - - 3.065e-230 729.0
HKD1_k127_5252792_1 PFAM binding-protein-dependent transport systems inner membrane component K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 407.0
HKD1_k127_5252792_2 Beta-lactamase enzyme family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 331.0
HKD1_k127_5252792_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 296.0
HKD1_k127_5252792_4 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15582 - - 0.00000000000000002653 83.0
HKD1_k127_5259981_0 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0033739,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 295.0
HKD1_k127_5259981_1 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000004588 162.0
HKD1_k127_5262628_0 Cobalt transport protein K02008 - - 0.00000000000000000000000000004274 122.0
HKD1_k127_5262628_1 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000004137 109.0
HKD1_k127_5262628_2 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02009 - - 0.00000000000000000000000004475 110.0
HKD1_k127_5265928_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0 1058.0
HKD1_k127_5265928_1 Polyprenyl synthetase K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 441.0
HKD1_k127_5265928_2 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 289.0
HKD1_k127_5265928_3 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000002317 259.0
HKD1_k127_5265928_4 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000004977 126.0
HKD1_k127_5265928_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000000000000002801 113.0
HKD1_k127_5268588_0 PFAM Metallophosphoesterase K07099 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 290.0
HKD1_k127_5273117_0 Citrate lyase alpha subunit K01643 - 2.8.3.10 7.304e-258 802.0
HKD1_k127_5273117_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 484.0
HKD1_k127_5273117_2 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase K01910 - 6.2.1.22 0.0000000000000000000000000000000000000000008363 159.0
HKD1_k127_5273117_3 Covalent carrier of the coenzyme of citrate lyase K01646 - - 0.000000000000000000000001108 106.0
HKD1_k127_5273117_4 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase K05964 - 2.7.7.61 0.00000000000007886 72.0
HKD1_k127_5277321_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 581.0
HKD1_k127_5277321_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000005281 83.0
HKD1_k127_5280612_0 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 355.0
HKD1_k127_5280612_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000005257 219.0
HKD1_k127_5280612_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000005637 81.0
HKD1_k127_5280810_0 Bacterial SH3 domain K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000001691 259.0
HKD1_k127_5280810_1 Belongs to the peptidase M50B family K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.0000002354 59.0
HKD1_k127_5280810_2 Domain of unknown function (DUF4163) - - - 0.000002368 58.0
HKD1_k127_5280810_3 Peptidase family M23 - - - 0.0001373 49.0
HKD1_k127_5282932_0 cell envelope-related function transcriptional attenuator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005656 269.0
HKD1_k127_5282932_1 cell envelope-related function transcriptional attenuator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002048 254.0
HKD1_k127_5284590_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 564.0
HKD1_k127_5284590_1 Hsp90 protein K04079 - - 0.000000000000000000000000000000000006582 137.0
HKD1_k127_5289475_0 - - - - 0.00000000000000000000000000000000006663 136.0
HKD1_k127_5289475_1 PFAM UbiE COQ5 methyltransferase - - - 0.0000000008801 60.0
HKD1_k127_5295363_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 537.0
HKD1_k127_5295363_1 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 307.0
HKD1_k127_5295363_2 polysaccharide biosynthetic process - - - 0.0000000000000000000000000006991 115.0
HKD1_k127_5299329_0 PFAM PrkA AAA domain K07180 - - 0.0 1108.0
HKD1_k127_5299329_1 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 548.0
HKD1_k127_5299329_2 stage V sporulation protein R K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 427.0
HKD1_k127_5299329_3 Putative threonine/serine exporter - - - 0.00000000000000000000000000000000000000000000000000001854 201.0
HKD1_k127_5300214_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K05565,K14086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 451.0
HKD1_k127_5300857_0 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system K02071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 456.0
HKD1_k127_5300857_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 340.0
HKD1_k127_5300857_2 Binding-protein-dependent transport system inner membrane component K02072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007812 254.0
HKD1_k127_5300857_3 Belongs to the nlpA lipoprotein family K02073 - - 0.0000000000000000000000000000000000000000000000000000000000002203 216.0
HKD1_k127_5305219_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 567.0
HKD1_k127_5305219_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000006943 249.0
HKD1_k127_5305219_2 aldolase class II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000001034 243.0
HKD1_k127_5305219_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000003779 141.0
HKD1_k127_5305219_4 Sigma-54 interaction domain - - - 0.00000005854 55.0
HKD1_k127_5310832_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 409.0
HKD1_k127_5310832_1 COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006839 268.0
HKD1_k127_5310832_2 - - - - 0.000000000000000000000000000000006407 141.0
HKD1_k127_5311586_0 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 387.0
HKD1_k127_5311586_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000174 266.0
HKD1_k127_5311586_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000002226 216.0
HKD1_k127_5311586_3 aspartate carbamoyltransferase, regulatory K00610 - - 0.000000000000000000000000000000000000000000000000000003094 194.0
HKD1_k127_5311586_4 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000291 52.0
HKD1_k127_5315300_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 546.0
HKD1_k127_5315300_1 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000000000101 160.0
HKD1_k127_5315300_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000006402 148.0
HKD1_k127_5315300_3 RNA-binding protein K07574 - - 0.0000000000000000000000000000000000004715 141.0
HKD1_k127_5315300_4 Cysteine protease Prp K07584 - - 0.000000000000001379 80.0
HKD1_k127_5315300_5 ribonuclease, Rne Rng family K08301 - - 0.0000000001291 68.0
HKD1_k127_5315784_0 sigma factor activity K03091,K03093 - - 0.00000000000000000000000000000000000000001355 158.0
HKD1_k127_5315784_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000003217 147.0
HKD1_k127_5315784_2 - - - - 0.0000000000000000000000000004236 114.0
HKD1_k127_5323766_0 Belongs to the SEDS family K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000921 372.0
HKD1_k127_5323766_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 0.000000000000000000000000007592 111.0
HKD1_k127_5324680_0 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 389.0
HKD1_k127_5324680_1 Thioredoxin - - - 0.000000000000000000000003548 104.0
HKD1_k127_5326454_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.896e-210 659.0
HKD1_k127_5326454_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000002922 72.0
HKD1_k127_5329433_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.763e-313 969.0
HKD1_k127_5332097_0 Manganese containing catalase K07217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 385.0
HKD1_k127_5332097_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 337.0
HKD1_k127_5337828_0 Aldehyde dehydrogenase family K13922 - 1.2.1.87 1.104e-200 630.0
HKD1_k127_5337828_1 RnfC Barrel sandwich hybrid domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 338.0
HKD1_k127_5338367_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 522.0
HKD1_k127_5338367_1 Collagen triple helix repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001066 230.0
HKD1_k127_5338367_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000003925 232.0
HKD1_k127_5338367_3 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000003309 179.0
HKD1_k127_5338367_4 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.0000000008919 62.0
HKD1_k127_5356658_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 406.0
HKD1_k127_5356658_1 Glutaredoxin - - - 0.00000000000000000004941 90.0
HKD1_k127_5363699_0 COG3279 Response regulator of the LytR AlgR family - - - 0.000000000000000000000001707 106.0
HKD1_k127_5363699_1 GHKL domain - - - 0.00000000000000000000004341 107.0
HKD1_k127_5366192_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005079 225.0
HKD1_k127_5374159_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 296.0
HKD1_k127_5374159_1 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000147 193.0
HKD1_k127_5380886_0 Bacterial extracellular solute-binding protein K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 469.0
HKD1_k127_5382758_0 Polysaccharide biosynthesis protein K06409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 392.0
HKD1_k127_5383741_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 344.0
HKD1_k127_5383741_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 315.0
HKD1_k127_5383741_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000006176 188.0
HKD1_k127_5383741_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000005625 186.0
HKD1_k127_5387218_0 - - - - 0.0004987 51.0
HKD1_k127_5390952_0 Na H antiporter K03315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 344.0
HKD1_k127_5390952_1 SPFH Band 7 PHB domain protein K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 291.0
HKD1_k127_5390952_2 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000001118 171.0
HKD1_k127_5390952_3 - - - - 0.0000000000000109 79.0
HKD1_k127_5396675_0 M18 family aminopeptidase K01267 - 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 487.0
HKD1_k127_54005_0 Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000000000000000000000000000000001944 193.0
HKD1_k127_54005_1 flagellar protein FliS K02422 - - 0.0003525 44.0
HKD1_k127_5405018_0 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 439.0
HKD1_k127_5405745_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 418.0
HKD1_k127_5405745_1 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 328.0
HKD1_k127_5405745_2 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000001254 236.0
HKD1_k127_5406058_0 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 289.0
HKD1_k127_5406058_1 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000004356 102.0
HKD1_k127_5409905_0 rRNA processing K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000009519 264.0
HKD1_k127_5409905_1 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000007975 227.0
HKD1_k127_5409905_2 Protein of unknown function (DUF554) K07150 - - 0.0000000000000001314 82.0
HKD1_k127_541301_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 436.0
HKD1_k127_541301_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000007946 222.0
HKD1_k127_541301_3 Peptidase dimerisation domain K21613 - - 0.000000000000000000000000000000005295 130.0
HKD1_k127_541301_4 PFAM Integrase catalytic region K07483,K07497 - - 0.0000000002008 61.0
HKD1_k127_5415474_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 297.0
HKD1_k127_5415474_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000005507 128.0
HKD1_k127_5415474_2 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000009425 106.0
HKD1_k127_5415474_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000001659 74.0
HKD1_k127_5416285_0 4Fe-4S single cluster domain - - - 8.085e-245 761.0
HKD1_k127_5421948_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 572.0
HKD1_k127_5425374_0 TIGRFAM arsenite-activated ATPase ArsA K01551 - 3.6.3.16 6.778e-310 956.0
HKD1_k127_5425374_1 TIGRFAM arsenical-resistance protein K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 556.0
HKD1_k127_5425374_2 Arsenical resistance operon trans-acting repressor ArsD - - - 0.0000000000000000000000000000000000000000000000000000001289 196.0
HKD1_k127_5425374_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000000001103 154.0
HKD1_k127_5425374_4 regulatory protein, arsR K03892 - - 0.000000000000000000000000000000000005529 139.0
HKD1_k127_5426113_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 499.0
HKD1_k127_5426113_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000002431 113.0
HKD1_k127_5434978_0 Belongs to the BCCT transporter (TC 2.A.15) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 494.0
HKD1_k127_5434978_1 Major Facilitator K08151,K08153 - - 0.000000000000000000000000000000000000000000000000000000007624 208.0
HKD1_k127_5442022_0 branched-chain amino acid permease (azaleucine resistance) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 294.0
HKD1_k127_5442022_1 Spore maturation protein K06373 - - 0.000000000000000000000000000000000000000000000000001641 188.0
HKD1_k127_5442022_2 Spore maturation protein K06374 - - 0.000000000000000000000000000000000000000000000000249 181.0
HKD1_k127_5442022_3 branched-chain amino acid - - - 0.000006783 49.0
HKD1_k127_5444255_0 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 393.0
HKD1_k127_5444470_0 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 462.0
HKD1_k127_5444470_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 351.0
HKD1_k127_5444470_2 PFAM pyridoxamine 5'-phosphate - - - 0.0000000000000000000000001372 110.0
HKD1_k127_5447933_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005764 254.0
HKD1_k127_5449465_0 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000157 246.0
HKD1_k127_5449836_0 elongation factor G - - - 0.00000000000000000000000000000000000000000000000000000000000000004272 228.0
HKD1_k127_5463075_0 ATPases associated with a variety of cellular activities K05833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 344.0
HKD1_k127_5463075_1 GAF domain K08968 - 1.8.4.14 0.000000000002409 68.0
HKD1_k127_5463511_0 CoA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 374.0
HKD1_k127_5469560_0 lactate/malate dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 391.0
HKD1_k127_5469560_1 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 378.0
HKD1_k127_5482338_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 451.0
HKD1_k127_5494461_0 ABC-type transport system, periplasmic component surface lipoprotein K07335 - - 1.759e-198 626.0
HKD1_k127_5494461_1 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000005833 158.0
HKD1_k127_5494461_2 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000001162 140.0
HKD1_k127_5495397_0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07502 - - 0.000000000000000000000000000000008734 139.0
HKD1_k127_5495798_0 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 491.0
HKD1_k127_5495798_1 DHHW protein - - - 0.00000000000000004851 89.0
HKD1_k127_5495877_0 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 430.0
HKD1_k127_5495877_1 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 398.0
HKD1_k127_5495877_2 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000171 188.0
HKD1_k127_5495877_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000000000000000000000000000317 160.0
HKD1_k127_5495877_4 Hit family K02503 - - 0.0000000000000000000000000000000000005835 142.0
HKD1_k127_5495877_5 Belongs to the UPF0102 family K07460 - - 0.000000000000000000004107 94.0
HKD1_k127_5495877_6 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000005131 94.0
HKD1_k127_5495877_7 sporulation protein K06438 - - 0.000000000000000004113 97.0
HKD1_k127_5495877_8 sporulation protein YqfC - - - 0.0000002343 56.0
HKD1_k127_5497613_0 cation transport ATPase K01533,K17686 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 284.0
HKD1_k127_5497613_1 negative regulation of transcription, DNA-templated K21600 - - 0.0000000000000000000000000000007104 123.0
HKD1_k127_5497667_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 473.0
HKD1_k127_5497667_1 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K03763 - 2.7.7.7 0.000000003335 57.0
HKD1_k127_5499075_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 410.0
HKD1_k127_5499075_1 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 383.0
HKD1_k127_5499075_2 sporulation integral membrane protein YtvI - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 297.0
HKD1_k127_5499075_3 GTP cyclohydrolase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001498 276.0
HKD1_k127_5499075_4 Channel protein, hemolysin III family K11068 - - 0.000000000000000000000000000000000000000000000000000000000000008392 221.0
HKD1_k127_5499075_5 SMART Metal-dependent phosphohydrolase, HD region K06950 - - 0.0000000000000000000000000000000000000000000000000000000000001416 216.0
HKD1_k127_5499075_6 Sporulation and spore germination - - - 0.000000000000000000000000000008507 124.0
HKD1_k127_5500779_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 445.0
HKD1_k127_5500779_1 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000009299 163.0
HKD1_k127_5501753_0 Formiminotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 437.0
HKD1_k127_5501753_1 HutD - - - 0.0000000000000000000000000000000000000000000000000000000000000002743 226.0
HKD1_k127_5501753_2 Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000000000000000000000000000000003205 201.0
HKD1_k127_5502106_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 467.0
HKD1_k127_5504699_0 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 464.0
HKD1_k127_5504847_0 mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000008312 246.0
HKD1_k127_5505027_0 oligoendopeptidase, M3 family - - - 1.503e-234 737.0
HKD1_k127_5505027_1 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000001068 220.0
HKD1_k127_5511525_0 Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 288.0
HKD1_k127_5511525_1 ThiS family - - - 0.000000000000000000003853 94.0
HKD1_k127_5514250_0 Magnesium transport protein CorA K03284 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000586 242.0
HKD1_k127_5516606_0 Belongs to the glutaminase family K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 308.0
HKD1_k127_5516606_1 Spore Coat Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001543 267.0
HKD1_k127_5516606_2 Protein of unknown function (DUF3810) - - - 0.00000000002227 70.0
HKD1_k127_5516861_0 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 362.0
HKD1_k127_5516861_1 Flavodoxin - - - 0.00000000000000000000002723 100.0
HKD1_k127_5526281_0 - - - - 0.000000000000000000000000000000000000000000000003395 186.0
HKD1_k127_5526281_1 - - - - 0.00000000001109 72.0
HKD1_k127_5527281_0 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 492.0
HKD1_k127_5527281_1 Binding-protein-dependent transport system inner membrane component K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 456.0
HKD1_k127_5527281_2 ABC transporter, ATP-binding protein K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 430.0
HKD1_k127_5527281_3 creatinase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 426.0
HKD1_k127_5527281_4 Psort location CytoplasmicMembrane, score 10.00 K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 422.0
HKD1_k127_5535165_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 3.116e-238 749.0
HKD1_k127_5536968_0 Voltage gated chloride channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 378.0
HKD1_k127_5536968_1 YbaK proline--tRNA ligase associated domain protein K19055 - - 0.0000006805 52.0
HKD1_k127_5538013_0 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 382.0
HKD1_k127_5538013_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 358.0
HKD1_k127_5544160_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 430.0
HKD1_k127_5544160_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000007944 60.0
HKD1_k127_5544160_2 Cold shock K03704 - - 0.00000002891 54.0
HKD1_k127_5549759_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 1.834e-206 651.0
HKD1_k127_5549759_1 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000172 277.0
HKD1_k127_5549759_2 S4 domain protein - - - 0.000000002177 59.0
HKD1_k127_5550823_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 586.0
HKD1_k127_5550823_1 ACT domain protein - - - 0.00000000000000000000000000001883 122.0
HKD1_k127_5555880_0 Pyridoxal-phosphate dependent enzyme K01753 - 4.3.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 302.0
HKD1_k127_5555880_1 Protein of unknown function (DUF2922) - - - 0.000000001233 61.0
HKD1_k127_5567392_0 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 357.0
HKD1_k127_5567392_1 RNA pseudouridylate synthase K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000002355 256.0
HKD1_k127_5574081_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 512.0
HKD1_k127_5574081_1 PP-loop family K04075,K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 331.0
HKD1_k127_5585309_0 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 329.0
HKD1_k127_5618929_0 ABC transporter - - - 8.416e-277 857.0
HKD1_k127_5618929_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0003059 46.0
HKD1_k127_5635181_0 SNARE associated Golgi protein - - - 0.00000000000000000000000000001533 123.0
HKD1_k127_5635181_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000001204 79.0
HKD1_k127_5635181_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - 0.0000000000000006192 84.0
HKD1_k127_5637974_0 CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 574.0
HKD1_k127_5637974_1 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000004472 174.0
HKD1_k127_5643245_0 AAA domain - - - 9.431e-277 870.0
HKD1_k127_5643245_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 562.0
HKD1_k127_5643245_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 427.0
HKD1_k127_5643245_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 370.0
HKD1_k127_5648962_0 FtsX-like permease family K02004 - - 9.846e-262 826.0
HKD1_k127_5657265_0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009992 378.0
HKD1_k127_5657265_1 ATPase. Has a role at an early stage in the morphogenesis of the spore coat K06398 GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000009378 120.0
HKD1_k127_5658192_0 DegV family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 321.0
HKD1_k127_5658192_1 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 321.0
HKD1_k127_5665574_0 Radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000001144 181.0
HKD1_k127_5665574_1 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000001033 123.0
HKD1_k127_5665574_2 Pfam:DUF1049 - - - 0.00003237 53.0
HKD1_k127_5684884_0 TIGRFAM UbiD family decarboxylases K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 421.0
HKD1_k127_5684884_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000526 184.0
HKD1_k127_5705214_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001611 239.0
HKD1_k127_5705214_1 - - - - 0.00000000000000000000000000000000000000000000000007016 188.0
HKD1_k127_573446_0 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005188 242.0
HKD1_k127_573446_1 Methyltransferase domain - - - 0.00000000000000000000000000009757 121.0
HKD1_k127_573446_2 Nodulation protein S (NodS) - - - 0.0000001544 53.0
HKD1_k127_5758073_0 potassium uptake protein, TrkH family K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 468.0
HKD1_k127_5758073_1 TrkA N-terminal domain protein K03499 - - 0.0000000000000000000000000000001131 126.0
HKD1_k127_5764051_0 selenium metabolism protein SsnA K20810 - 3.5.4.40 2.221e-232 724.0
HKD1_k127_5764051_1 permease K03458 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 422.0
HKD1_k127_5764051_2 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 368.0
HKD1_k127_5766584_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 607.0
HKD1_k127_5770130_0 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 313.0
HKD1_k127_5770130_1 methyl-accepting chemotaxis protein K03406 - - 0.00002678 49.0
HKD1_k127_5772506_0 Belongs to the peptidase S16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 529.0
HKD1_k127_5772506_1 protein conserved in bacteria - - - 0.00000001131 56.0
HKD1_k127_5773450_0 Small, acid-soluble spore proteins, alpha/beta type - - - 0.0000000000008206 70.0
HKD1_k127_5773867_0 Formyltetrahydrofolate synthetase K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 456.0
HKD1_k127_5773867_1 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000002844 224.0
HKD1_k127_5781252_0 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000000003669 167.0
HKD1_k127_5781252_1 LysM domain - - - 0.0000000000000000000000000000236 120.0
HKD1_k127_5781252_2 ABC transporter, permease protein K02029,K17073,K17074 - - 0.00000001568 56.0
HKD1_k127_5786231_0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 501.0
HKD1_k127_5786231_1 ATPase domain of DNA mismatch repair MUTS family K07456 - - 0.000000000000000000000000000000001371 132.0
HKD1_k127_5789500_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 1.438e-257 801.0
HKD1_k127_5789500_1 Domain of unknown function (DUF3787) - - - 0.0000000000000000004558 89.0
HKD1_k127_5795492_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000001936 223.0
HKD1_k127_5795492_1 elongation factor G - - - 0.00000000000000000000000000000000000000000000000000000000000003881 219.0
HKD1_k127_5798154_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 455.0
HKD1_k127_5798154_1 Single-stranded-DNA-specific exonuclease recj K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 377.0
HKD1_k127_5798154_2 Phosphodiester glycosidase - - - 0.0000000000004392 73.0
HKD1_k127_5822526_0 DMT(Drug metabolite transporter) superfamily permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001155 252.0
HKD1_k127_5822526_1 Uncharacterized conserved protein (DUF2164) - - - 0.000000000000000000000000000002082 121.0
HKD1_k127_5822526_2 methylglyoxal synthase K00859,K01734 - 2.7.1.24,4.2.3.3 0.0000000000000005561 78.0
HKD1_k127_5826380_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 5.948e-222 693.0
HKD1_k127_5826380_1 Permease K02824 - - 0.00000000000000000000000000000000000000000000000000000000000000000004032 233.0
HKD1_k127_5826969_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 446.0
HKD1_k127_5826969_1 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 333.0
HKD1_k127_5826969_2 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009526 273.0
HKD1_k127_5826969_3 amidohydrolase K01436 - - 0.0000000000000000000000000000000000000004073 151.0
HKD1_k127_5833000_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 500.0
HKD1_k127_5833000_1 Methyltransferase, chemotaxis proteins K00575 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006479,GO:0006807,GO:0006935,GO:0008022,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0008983,GO:0009605,GO:0009987,GO:0010340,GO:0016020,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0032991,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051998,GO:0071704,GO:0071944,GO:0098561,GO:0140096,GO:1901564 2.1.1.80 0.00000000000000000000001158 102.0
HKD1_k127_5842870_0 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 378.0
HKD1_k127_5842870_1 Bacterial transferase hexapeptide repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 287.0
HKD1_k127_5842870_2 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000002421 180.0
HKD1_k127_5842870_3 iron-only hydrogenase system regulator - - - 0.00000000000000000000000000000000153 131.0
HKD1_k127_5847715_0 SNF2 family N-terminal domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 395.0
HKD1_k127_5850510_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 411.0
HKD1_k127_5850510_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 365.0
HKD1_k127_5850510_2 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 332.0
HKD1_k127_5850510_3 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000003344 233.0
HKD1_k127_5850510_4 PFAM Accessory gene regulator B K07813 - - 0.0000000000000000000000007308 107.0
HKD1_k127_5850510_5 Psort location - - - 0.0000000000000000000004586 100.0
HKD1_k127_5850510_6 - - - - 0.000000000000000008422 89.0
HKD1_k127_5851433_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1027.0
HKD1_k127_5851433_1 basic membrane K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 531.0
HKD1_k127_5851433_2 transcriptional regulator, MerR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 312.0
HKD1_k127_5851433_3 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 298.0
HKD1_k127_5851433_4 4Fe-4S dicluster domain K05796 - - 0.00000000000000000000000000000000000000000000000000000000002834 207.0
HKD1_k127_5851433_6 spore protein K06434 - - 0.0001697 46.0
HKD1_k127_5852715_0 C4-dicarboxylate anaerobic carrier - - - 3.153e-231 722.0
HKD1_k127_5853798_0 COG COG1951 Tartrate dehydratase alpha subunit Fumarate hydratase class I, N-terminal domain K03779 - 4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 318.0
HKD1_k127_5853798_1 Fumarase C-terminus K03780 GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896 4.2.1.32 0.00000000000000000000000000000000000000000000000000000007668 196.0
HKD1_k127_5853798_2 Tartrate K03779 GO:0008150,GO:0008152,GO:1901275 4.2.1.32 0.000000000000000000000000000002345 120.0
HKD1_k127_5856473_0 PFAM surface presentation of antigens (SPOA) K02417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 322.0
HKD1_k127_5856473_1 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000125 284.0
HKD1_k127_5856473_2 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000006179 180.0
HKD1_k127_5856473_3 Bacterial export proteins, family 3 K02420 - - 0.00000000000000000000006143 100.0
HKD1_k127_5856473_4 Bacterial export proteins, family 1 K02421 - - 0.000000000000094 74.0
HKD1_k127_5856473_5 Flagellar biosynthesis protein, FliO K02418 - - 0.000002576 55.0
HKD1_k127_5856504_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.632e-247 775.0
HKD1_k127_5856610_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000005046 177.0
HKD1_k127_5856610_1 ABC transporter, substrate-binding protein, family 5 K02035 - - 0.0000000000000001933 83.0
HKD1_k127_5856966_0 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 300.0
HKD1_k127_5856966_1 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000002699 194.0
HKD1_k127_5856966_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000006565 72.0
HKD1_k127_5884746_0 PFAM Major Facilitator Superfamily - - - 3.306e-202 636.0
HKD1_k127_5884746_1 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 416.0
HKD1_k127_5892368_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 3.479e-297 918.0
HKD1_k127_5892368_1 FR47-like protein - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - 0.00000001712 61.0
HKD1_k127_5893546_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1875.0
HKD1_k127_5893546_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1781.0
HKD1_k127_5893546_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.661e-286 887.0
HKD1_k127_5893546_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 292.0
HKD1_k127_5893546_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003 275.0
HKD1_k127_5893546_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000003348 228.0
HKD1_k127_5893546_6 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000002271 221.0
HKD1_k127_5893546_7 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K07590 - - 0.0000000000000001508 81.0
HKD1_k127_5896946_0 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) K07862 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 557.0
HKD1_k127_5896946_1 MATE efflux family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 542.0
HKD1_k127_5896946_2 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001498 224.0
HKD1_k127_5896946_3 PFAM Lysine exporter protein (LYSE YGGA) K11249 - - 0.0000000000000000000000000000000000000000000002852 169.0
HKD1_k127_5897397_0 S-layer homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000007985 239.0
HKD1_k127_5897397_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000003751 186.0
HKD1_k127_5898801_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 366.0
HKD1_k127_5898801_1 - - - - 0.000000000000008505 77.0
HKD1_k127_5902257_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 341.0
HKD1_k127_5902257_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000001033 74.0
HKD1_k127_5904119_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 3.814e-292 908.0
HKD1_k127_5904119_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 6.496e-271 837.0
HKD1_k127_5904119_2 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 349.0
HKD1_k127_5917151_0 Stage V sporulation protein AD K06406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 298.0
HKD1_k127_5917151_1 stage V sporulation protein AC K06405 - - 0.00000000000000000000000000000000000000000136 160.0
HKD1_k127_5920371_0 Abc transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001495 258.0
HKD1_k127_5920371_1 Transcriptional regulator K07979 - - 0.0000000000000000000001829 101.0
HKD1_k127_5920371_2 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.00001421 58.0
HKD1_k127_5923992_0 Glycosyl hydrolase family 26 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 340.0
HKD1_k127_5923992_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000004353 179.0
HKD1_k127_5923992_2 - - - - 0.000000000000000000000004797 105.0
HKD1_k127_5946191_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 320.0
HKD1_k127_5946191_1 GNAT family - - - 0.00000000000000000000000000000000000000000000000005466 182.0
HKD1_k127_5946191_2 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000005885 168.0
HKD1_k127_5946191_3 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000131 138.0
HKD1_k127_5950915_0 Alanine racemase, N-terminal domain K21898 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0019842,GO:0036094,GO:0036361,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0048037,GO:0050157,GO:0070279,GO:0070280,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901605 5.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 441.0
HKD1_k127_5950915_1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K02395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 435.0
HKD1_k127_5950915_2 MutL protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006919 246.0
HKD1_k127_5952992_0 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 458.0
HKD1_k127_5952992_1 Formiminotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 454.0
HKD1_k127_5952992_2 Formiminotransferase-cyclodeaminase - - - 0.000000000000000002415 86.0
HKD1_k127_5955176_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 359.0
HKD1_k127_5955176_1 Metallopeptidase family M24 K01262 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000002162 239.0
HKD1_k127_5982472_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 426.0
HKD1_k127_6043102_0 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000002561 188.0
HKD1_k127_6043102_1 Radical SAM - - - 0.000000000001163 69.0
HKD1_k127_6050618_0 Iron only hydrogenase large subunit, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 553.0
HKD1_k127_6050618_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000001651 151.0
HKD1_k127_6050618_2 Carbohydrate-binding domain-containing protein Cthe_2159 - GO:0001871,GO:0003674,GO:0005488,GO:0005509,GO:0030246,GO:0030247,GO:0030248,GO:0043167,GO:0043169,GO:0046872,GO:0048028,GO:2001062 - 0.0000000000000000000000000000000000003518 147.0
HKD1_k127_6065566_0 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 343.0
HKD1_k127_6065566_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833,K03851,K12256,K15372 - 2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77 0.00000000000000000000000000000000000000000000000000000005952 197.0
HKD1_k127_6072085_0 cell wall hydrolase K01449 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000007485 269.0
HKD1_k127_6072085_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000005963 225.0
HKD1_k127_6072085_2 protein conserved in bacteria - - - 0.0000000000000005999 83.0
HKD1_k127_6086864_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.073e-305 948.0
HKD1_k127_6086864_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.561e-304 943.0
HKD1_k127_6086864_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004477 268.0
HKD1_k127_6096871_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 334.0
HKD1_k127_6096871_1 RnfC Barrel sandwich hybrid domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001176 226.0
HKD1_k127_6096871_2 BMC domain - - - 0.0000000000000000000000000000000000000000000000000000002635 199.0
HKD1_k127_6096871_3 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate K00899 - 2.7.1.100 0.00003926 48.0
HKD1_k127_6112891_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 3.666e-208 658.0
HKD1_k127_6112891_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 477.0
HKD1_k127_6112891_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 318.0
HKD1_k127_6112891_3 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000001118 212.0
HKD1_k127_6141182_0 Transporter, CPA2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 355.0
HKD1_k127_6141182_1 4Fe-4S binding domain - - - 0.000000008282 57.0
HKD1_k127_6156929_0 DHHW protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003901 234.0
HKD1_k127_6156929_1 - - - - 0.00000000000000000000000000000001163 133.0
HKD1_k127_6156929_2 S-layer homology domain - - - 0.0000007424 56.0
HKD1_k127_6158442_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 5.25e-218 683.0
HKD1_k127_6179279_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002633 271.0
HKD1_k127_6179279_1 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000000000000000002154 199.0
HKD1_k127_6179279_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000702 155.0
HKD1_k127_6211853_0 Electron transfer flavoprotein K03522 - - 1.206e-205 644.0
HKD1_k127_6211853_1 FAD linked oxidase domain protein K00104 - 1.1.3.15 4.761e-199 623.0
HKD1_k127_6211853_2 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 432.0
HKD1_k127_6211853_3 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001125 247.0
HKD1_k127_6212838_0 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.0000000000000000000000000000008392 127.0
HKD1_k127_6212838_1 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.00000000000000000000000001901 113.0
HKD1_k127_6212838_2 PTS system sorbose-specific iic component K02795,K17466 - - 0.000000000000000007826 89.0
HKD1_k127_6213814_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 599.0
HKD1_k127_6213814_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 556.0
HKD1_k127_6213814_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 472.0
HKD1_k127_6213814_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 434.0
HKD1_k127_6213814_4 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 351.0
HKD1_k127_6213814_5 Psort location CytoplasmicMembrane, score K01996 - - 0.00000000000000000000000000002146 121.0
HKD1_k127_6216843_0 PFAM Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005217 264.0
HKD1_k127_6216843_1 Diguanylate cyclase - - - 0.00000000000000000000008952 98.0
HKD1_k127_6228591_0 of the major facilitator superfamily - - - 4.371e-233 725.0
HKD1_k127_6228591_1 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 400.0
HKD1_k127_6228591_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000005222 69.0
HKD1_k127_6228591_3 PFAM Transposase IS66 family - - - 0.000000006944 59.0
HKD1_k127_6228591_4 Psort location Cytoplasmic, score - - - 0.000001606 50.0
HKD1_k127_6231224_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1210.0
HKD1_k127_6231224_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 382.0
HKD1_k127_6231224_2 permease K03458 - - 0.000000000000000000000062 98.0
HKD1_k127_6243364_0 Prolyl oligopeptidase family K01303 - 3.4.19.1 1.803e-277 865.0
HKD1_k127_6243364_1 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 578.0
HKD1_k127_6243364_2 Amino acid amide ABC transporter membrane protein 2, HAAT family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 477.0
HKD1_k127_6243364_3 Amino acid amide ABC transporter membrane protein 1, HAAT family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 459.0
HKD1_k127_6243364_4 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 424.0
HKD1_k127_6243364_5 Psort location CytoplasmicMembrane, score K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 309.0
HKD1_k127_6243364_6 CBS domain containing protein K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 304.0
HKD1_k127_6243364_7 - - - - 0.00003134 48.0
HKD1_k127_6260021_0 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 526.0
HKD1_k127_6260021_1 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000002709 215.0
HKD1_k127_6270290_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 544.0
HKD1_k127_6270290_1 PFAM Uncharacterised ACR, YkgG family COG1556 - - - 0.000000000000000000000000000000000000000000000000000000000000000008717 231.0
HKD1_k127_6270290_2 hmm pf01594 - - - 0.000000000004329 67.0
HKD1_k127_6270351_0 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 471.0
HKD1_k127_6289539_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738,K12339,K21400 GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 2.3.1.263,2.5.1.47 2.16e-229 717.0
HKD1_k127_6289539_1 dihydrodipicolinate reductase K21672 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047530,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000001613 233.0
HKD1_k127_6289539_2 - K21399 GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 2.3.1.263 0.0000000000000000000000000000000000000000000003749 168.0
HKD1_k127_6298488_0 PFAM carboxyl transferase - - - 6.511e-304 935.0
HKD1_k127_6298488_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 589.0
HKD1_k127_6298488_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 477.0
HKD1_k127_6298488_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000002719 159.0
HKD1_k127_6301734_0 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02342,K03763 - 2.7.7.7 1.524e-194 615.0
HKD1_k127_6305620_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.4.1.3,1.4.1.4 6.088e-229 715.0
HKD1_k127_6312227_0 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002815 267.0
HKD1_k127_6312227_1 Macrocin-O-methyltransferase (TylF) K05303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002278 254.0
HKD1_k127_6337720_0 AAA domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 460.0
HKD1_k127_6337720_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000001505 154.0
HKD1_k127_6338191_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1322.0
HKD1_k127_6338522_0 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 551.0
HKD1_k127_6338522_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 282.0
HKD1_k127_6338522_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000004299 164.0
HKD1_k127_6338522_3 Prokaryotic diacylglycerol kinase - - - 0.00000000000000000000000002279 113.0
HKD1_k127_6338522_4 Psort location Cytoplasmic, score - - - 0.0000000000007599 68.0
HKD1_k127_6344969_0 - K16788 - - 0.00000000000000000000000000000000000000000000000000000000000075 217.0
HKD1_k127_6344969_1 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000009314 211.0
HKD1_k127_6344969_2 regulation of RNA biosynthetic process K07105 - - 0.0000000000000000000000000000000000000000000000000001599 191.0
HKD1_k127_6344969_3 Transcriptional regulator - - - 0.00000000000000000000000000000001355 133.0
HKD1_k127_6344969_4 - - - - 0.000000000004877 66.0
HKD1_k127_6345252_0 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 330.0
HKD1_k127_6345252_1 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000004014 193.0
HKD1_k127_6345252_2 4Fe-4S binding domain - - - 0.00000000000000002297 83.0
HKD1_k127_6345252_3 Small, acid-soluble spore proteins, alpha/beta type - - - 0.0000000000000005932 79.0
HKD1_k127_6347155_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000001717 197.0
HKD1_k127_6351011_0 malic enzyme K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 523.0
HKD1_k127_6351011_1 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 306.0
HKD1_k127_6351011_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000009873 184.0
HKD1_k127_6353932_0 RNA pseudouridylate synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 299.0
HKD1_k127_6353932_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000002042 255.0
HKD1_k127_6353932_2 histidine kinase - - - 0.000000000000000000006408 94.0
HKD1_k127_6358205_0 - - - - 0.000000000000000000000000000000000000000000000000000000000004702 209.0
HKD1_k127_6358205_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000004776 181.0
HKD1_k127_6358205_2 Domain of unknown function (DUF4180) - - - 0.000000000000000000000000000000000000000002826 157.0
HKD1_k127_6358205_3 - - - - 0.000000000000000008735 89.0
HKD1_k127_635911_0 ABC-type nitrate sulfonate bicarbonate transport system, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 374.0
HKD1_k127_635911_1 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 370.0
HKD1_k127_635911_2 ABC-type nitrate sulfonate bicarbonate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 368.0
HKD1_k127_635911_3 Thiamine-binding protein - - - 0.00000000000001265 78.0
HKD1_k127_6360544_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008702 241.0
HKD1_k127_6360544_1 Cadmium resistance transporter - - - 0.00000000000000000000000000000000000000000000000000001714 195.0
HKD1_k127_6360544_2 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000000000000000001742 170.0
HKD1_k127_6360544_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000000003599 167.0
HKD1_k127_6360544_4 transcriptional regulator - - - 0.0003314 43.0
HKD1_k127_6361953_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833,K03851,K12256,K15372 - 2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 447.0
HKD1_k127_6361953_1 Catalyzes the sodium-dependent transport of glutamate K03312 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 341.0
HKD1_k127_6371811_0 precorrin-3B C17-methyltransferase K05934,K21479 - 2.1.1.131,2.1.1.272 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 327.0
HKD1_k127_6371811_1 Precorrin-2 C(20)-methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 286.0
HKD1_k127_6371811_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009077 274.0
HKD1_k127_6385163_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 465.0
HKD1_k127_6385163_1 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000004883 213.0
HKD1_k127_6394178_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 559.0
HKD1_k127_6400003_0 Belongs to the AlaDH PNT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 567.0
HKD1_k127_6400003_1 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.0004132 44.0
HKD1_k127_6403101_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 376.0
HKD1_k127_6403101_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 285.0
HKD1_k127_6403526_0 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 338.0
HKD1_k127_6407505_0 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 524.0
HKD1_k127_6407505_1 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000001959 136.0
HKD1_k127_6407505_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000005466 126.0
HKD1_k127_6409910_0 Belongs to the binding-protein-dependent transport system permease family K05832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 379.0
HKD1_k127_6409910_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000006991 154.0
HKD1_k127_6409910_2 ABC transporter, ATP-binding protein K05833 - - 0.000000000000006068 75.0
HKD1_k127_6414469_0 2-keto-3-deoxygluconate permease K02526 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 514.0
HKD1_k127_6415500_0 Type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 348.0
HKD1_k127_6415500_1 Prepilin-type N-terminal cleavage methylation domain K02456,K02650 - - 0.0000001258 59.0
HKD1_k127_6416571_0 peptidase S8 and S53, subtilisin, kexin, sedolisin K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 411.0
HKD1_k127_6416571_1 PFAM response regulator receiver K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 288.0
HKD1_k127_6416571_2 Histidine kinase K07652 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007296 275.0
HKD1_k127_641905_0 Belongs to the complex I 49 kDa subunit family K00333,K14090 - 1.6.5.3 1.565e-195 613.0
HKD1_k127_641905_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K14091 - - 0.00000000000000000000000000000000000000000000001052 173.0
HKD1_k127_641905_2 NADH dehydrogenase K14089 - - 0.00000000000000000000000000000000000202 139.0
HKD1_k127_6421795_0 Major Facilitator K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 376.0
HKD1_k127_6421795_1 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000002154 167.0
HKD1_k127_6421895_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 481.0
HKD1_k127_642911_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 456.0
HKD1_k127_642911_1 AP endonuclease family 2 C terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 302.0
HKD1_k127_642911_2 ABC-type sugar transport system, periplasmic K10439 - - 0.00000008695 57.0
HKD1_k127_6441259_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000139 267.0
HKD1_k127_6461298_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 3.111e-195 618.0
HKD1_k127_6461298_1 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000005845 209.0
HKD1_k127_6461298_2 - - - - 0.00000000000001429 85.0
HKD1_k127_6461298_3 - - - - 0.000000000001514 79.0
HKD1_k127_647707_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 438.0
HKD1_k127_647707_1 regulatory protein, arsR - - - 0.00000000000001386 74.0
HKD1_k127_6478603_0 Beta-eliminating lyase K01667 - 4.1.99.1 5.022e-218 682.0
HKD1_k127_6478603_1 ATPases associated with a variety of cellular activities K06158 - - 0.0000000000000000000000000000000000000000000000000000000000003062 213.0
HKD1_k127_6488067_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 468.0
HKD1_k127_6488067_1 Psort location Cytoplasmic, score K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000001351 215.0
HKD1_k127_6488067_2 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K20445 - 1.17.1.5 0.00000000000000000000000000000000355 135.0
HKD1_k127_6511733_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 397.0
HKD1_k127_6511733_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000003252 200.0
HKD1_k127_6511733_2 Domain of unknown function (DUF4163) - - - 0.000000000000000000000000000000000000000000000000001113 190.0
HKD1_k127_6511733_3 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000007454 169.0
HKD1_k127_6511733_4 PFAM LysM domain - - - 0.000000000000000000000000000000000000000009619 162.0
HKD1_k127_6512885_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 7.863e-207 671.0
HKD1_k127_6512885_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 472.0
HKD1_k127_6512885_2 Clp protease K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 289.0
HKD1_k127_6512885_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000007323 162.0
HKD1_k127_6528525_0 PAP2 superfamily - - - 1.788e-211 669.0
HKD1_k127_6528525_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000002244 70.0
HKD1_k127_6535212_0 PFAM Phosphate acetyl butaryl transferase K00634 - 2.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 300.0
HKD1_k127_6535212_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000001789 253.0
HKD1_k127_6535212_2 FMN binding - - - 0.000000000000000000000000000000000000000000001715 169.0
HKD1_k127_6535212_3 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) - - - 0.0000000000000000005663 87.0
HKD1_k127_6541222_0 Spore germination protein K06310 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 487.0
HKD1_k127_6541222_1 PFAM spore germination K06296,K06311 - - 0.00000000000000000000003603 112.0
HKD1_k127_6541222_2 PFAM spore germination B3 GerAC family protein K06297 - - 0.000000308 53.0
HKD1_k127_6541382_0 Spore germination B3/ GerAC like, C-terminal K06297 - - 0.00000000000000000000000000000000000000001113 167.0
HKD1_k127_6541382_1 PFAM Sporulation stage II protein R K06387 - - 0.000000000000000000002142 98.0
HKD1_k127_6545803_0 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02342,K03763 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 580.0
HKD1_k127_6545803_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 432.0
HKD1_k127_6545803_2 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000006868 146.0
HKD1_k127_6545803_3 Protein of unknown function (DUF448) K07742 - - 0.000000000000000000000000000001751 122.0
HKD1_k127_6545803_4 PFAM ribosomal protein L7Ae L30e S12e Gadd45 - - - 0.0000000000000001637 82.0
HKD1_k127_6545803_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000005163 55.0
HKD1_k127_6546712_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 9.758e-250 793.0
HKD1_k127_6546712_1 Collagenase K08303 - - 0.000000000000000000000000000000000000000000000000001536 198.0
HKD1_k127_6546712_2 Acetyltransferase (GNAT) domain - - - 0.00000000000361 76.0
HKD1_k127_6548509_0 Na H antiporter K03315 - - 0.00000000000000000000000000000000000000000000000008655 183.0
HKD1_k127_6548509_1 metallo-beta-lactamase - - - 0.000000000000000000000000000000000000000000000003765 177.0
HKD1_k127_6549721_0 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 426.0
HKD1_k127_6549721_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 314.0
HKD1_k127_6550901_0 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 393.0
HKD1_k127_6550901_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000006991 196.0
HKD1_k127_6550901_2 Polysaccharide biosynthesis protein - - - 0.00000000217 58.0
HKD1_k127_6557628_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 309.0
HKD1_k127_6557628_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000002569 248.0
HKD1_k127_6563698_0 potassium uptake protein, TrkH family K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 297.0
HKD1_k127_6578731_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 357.0
HKD1_k127_6581365_0 Na H antiporter - - - 3.814e-212 670.0
HKD1_k127_6581365_1 endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000004651 197.0
HKD1_k127_6581365_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000001276 179.0
HKD1_k127_6585145_0 ATPase domain of DNA mismatch repair MUTS family K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 332.0
HKD1_k127_6585145_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 302.0
HKD1_k127_6585145_2 lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000002157 64.0
HKD1_k127_6587461_0 stage II sporulation protein D K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007913 258.0
HKD1_k127_6587461_1 Stage III sporulation protein D K06283 - - 0.000000000000000000000000000001617 122.0
HKD1_k127_6587461_2 peptidase - - - 0.00000000000000000000000000002101 126.0
HKD1_k127_6592461_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002336 273.0
HKD1_k127_6592461_1 amidohydrolase - - - 0.00000000000000000000000000000000001621 136.0
HKD1_k127_6593113_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 352.0
HKD1_k127_6593113_1 Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 352.0
HKD1_k127_6593113_2 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 310.0
HKD1_k127_6593113_3 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001652 257.0
HKD1_k127_6593113_4 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000000000000001699 237.0
HKD1_k127_6593113_5 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.0000000001709 61.0
HKD1_k127_6593997_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 416.0
HKD1_k127_6612496_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.86e-248 775.0
HKD1_k127_6612496_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.438e-196 619.0
HKD1_k127_6612496_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000004271 119.0
HKD1_k127_6619513_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008668 536.0
HKD1_k127_6624419_0 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 339.0
HKD1_k127_6626350_0 ATPase (AAA superfamily) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000002484 229.0
HKD1_k127_6626350_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000002162 214.0
HKD1_k127_6626350_2 Putative zinc-finger - - - 0.000000000001756 72.0
HKD1_k127_6644703_0 FMN-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 379.0
HKD1_k127_6647056_0 Belongs to the sulfur carrier protein TusA family - - - 3.316e-260 807.0
HKD1_k127_6647322_0 Abc transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005637 277.0
HKD1_k127_6656375_0 LysM domain - - - 0.000000000000000001724 93.0
HKD1_k127_6666181_0 Psort location Cytoplasmic, score K07720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 296.0
HKD1_k127_6666181_1 Sensory domain found in PocR K02478,K08082 - 2.7.13.3 0.00000000000000000000003736 102.0
HKD1_k127_6675815_0 Transcriptional regulator, LacI family K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 379.0
HKD1_k127_6675815_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000003464 63.0
HKD1_k127_6691759_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 502.0
HKD1_k127_6691759_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 338.0
HKD1_k127_6694848_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 403.0
HKD1_k127_6699003_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 359.0
HKD1_k127_6699003_1 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 289.0
HKD1_k127_6726968_0 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 530.0
HKD1_k127_6726968_1 PFAM HD domain - - - 0.000004406 51.0
HKD1_k127_6742006_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 413.0
HKD1_k127_6742006_1 Radical SAM domain protein - - - 0.00000000000000000003274 90.0
HKD1_k127_6745607_0 Negative regulator of genetic competence clpC mecB K03697 - - 0.0 1023.0
HKD1_k127_6745607_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 364.0
HKD1_k127_6745607_2 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate K00674,K05822 - 2.3.1.117,2.3.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 317.0
HKD1_k127_6745607_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005911 269.0
HKD1_k127_6745607_4 EDD domain protein, DegV family - - - 0.000000000000000000000000000000000000000000000000000000000000002063 228.0
HKD1_k127_6745607_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000001497 151.0
HKD1_k127_6745607_6 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000005091 142.0
HKD1_k127_6751710_0 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000104 221.0
HKD1_k127_6751710_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000135 143.0
HKD1_k127_6751710_2 metalloprotease K11749 - - 0.0000000000000000000000000000000000009045 144.0
HKD1_k127_6755201_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 297.0
HKD1_k127_6759312_0 DNA binding domain, excisionase family K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 583.0
HKD1_k127_6759312_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000001767 265.0
HKD1_k127_6759969_0 Protein of unknown function (DUF445) - - - 0.000000002293 63.0
HKD1_k127_6759969_1 efflux transmembrane transporter activity - - - 0.00000005622 61.0
HKD1_k127_6765608_0 Abc transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 547.0
HKD1_k127_6765608_1 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 448.0
HKD1_k127_6765608_2 Sporulation and spore germination K06298 - - 0.00000000000000000000000000000000000000000000000000000000000000001012 237.0
HKD1_k127_6765608_3 Phosphate transporter family K03306 - - 0.00000000009461 62.0
HKD1_k127_6766700_0 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 363.0
HKD1_k127_6766700_1 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 321.0
HKD1_k127_6792633_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 3.166e-289 897.0
HKD1_k127_6792633_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 3.601e-285 888.0
HKD1_k127_6792633_2 iron hydrogenase, small subunit K00336,K18332 - 1.12.1.3,1.6.5.3 5.673e-258 807.0
HKD1_k127_6792633_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 553.0
HKD1_k127_6792633_4 sporulation initiation inhibitor protein Soj K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 362.0
HKD1_k127_6792633_5 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 286.0
HKD1_k127_6792633_6 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000001327 263.0
HKD1_k127_6792633_7 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000166 265.0
HKD1_k127_6792633_8 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330,K22340 - 1.12.1.3,1.17.1.11,1.6.5.3 0.0000000000000000000000000000000000000000000000000000002157 198.0
HKD1_k127_6792633_9 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000000000000001726 169.0
HKD1_k127_6806585_0 2-nitropropane dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 389.0
HKD1_k127_6806585_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 332.0
HKD1_k127_6806585_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
HKD1_k127_6806585_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.00000000000000000002585 92.0
HKD1_k127_6809389_0 PFAM Glycine sarcosine betaine reductase complex, protein B, alpha and beta subunits K10671 - 1.21.4.2 2.829e-201 630.0
HKD1_k127_6809389_1 Psort location Cytoplasmic, score 8.87 K10672 - 1.21.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 546.0
HKD1_k127_6832001_0 PFAM major facilitator superfamily MFS_1 K08170 - - 3.142e-240 749.0
HKD1_k127_6832001_1 amidohydrolase - - - 3.778e-230 715.0
HKD1_k127_6832001_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000001846 235.0
HKD1_k127_6832001_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000001937 132.0
HKD1_k127_6837478_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.866e-268 838.0
HKD1_k127_6837478_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 605.0
HKD1_k127_6837478_2 Electron transfer flavoprotein FAD-binding domain K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 447.0
HKD1_k127_6837478_3 Psort location Cytoplasmic, score K03521,K22431 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 420.0
HKD1_k127_6837478_4 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715,K15866,K20036 - 4.2.1.155,4.2.1.17,5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 366.0
HKD1_k127_6837478_5 domain protein K06959 - - 0.0000000000000000000000000000000000000000000000001479 178.0
HKD1_k127_6837478_6 IA, variant 1 K01091,K06019 - 3.1.3.18,3.6.1.1 0.0000000000000000000000000000000000000007926 156.0
HKD1_k127_683970_0 AAA domain - - - 0.00000000000000000000000000000008668 138.0
HKD1_k127_683970_1 DNA repair exonuclease K03547 - - 0.00000000000000000000000001206 118.0
HKD1_k127_6851716_0 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000332 266.0
HKD1_k127_6862748_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 1.513e-195 615.0
HKD1_k127_6862748_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000007261 108.0
HKD1_k127_6883669_0 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 453.0
HKD1_k127_6883669_1 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001781 245.0
HKD1_k127_6883669_2 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000008506 200.0
HKD1_k127_68925_0 Oxidoreductase K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 434.0
HKD1_k127_6901362_0 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000883 201.0
HKD1_k127_6901362_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000001358 155.0
HKD1_k127_6901362_2 Protein of unknown function (DUF1294) - - - 0.000000000000001731 79.0
HKD1_k127_6917234_0 Catalyzes the formation of L-proline from pyrroline-5-carboxylate K00286,K02239 - 1.5.1.2 0.00000000000000000000000000000000007712 143.0
HKD1_k127_6917234_1 Tartrate K03779 GO:0008150,GO:0008152,GO:1901275 4.2.1.32 0.00003723 46.0
HKD1_k127_692252_0 resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 428.0
HKD1_k127_692252_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 343.0
HKD1_k127_692252_2 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000003409 98.0
HKD1_k127_692252_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000006459 68.0
HKD1_k127_6937298_0 Elongation factor G C-terminus K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 550.0
HKD1_k127_6937298_1 Bacterial regulatory protein, Fis family K06714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 518.0
HKD1_k127_6937298_2 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 - 4.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000006496 237.0
HKD1_k127_6946222_0 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 313.0
HKD1_k127_6946222_1 Copper amine oxidase N-terminal domain - - - 0.0003772 48.0
HKD1_k127_6951160_0 ATPases associated with a variety of cellular activities K05833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 342.0
HKD1_k127_6951160_1 PFAM 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 332.0
HKD1_k127_6951160_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 328.0
HKD1_k127_6951160_3 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000001745 170.0
HKD1_k127_6951160_4 Belongs to the binding-protein-dependent transport system permease family K05832 - - 0.0000000000000000000000000000000000000000004877 160.0
HKD1_k127_6951160_5 DNA repair exonuclease K03547 - - 0.00000000000000000000000002068 113.0
HKD1_k127_6969611_0 Catalyzes the sodium-dependent transport of glutamate K03312 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 535.0
HKD1_k127_6969611_1 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000001094 119.0
HKD1_k127_6973198_0 Belongs to the 'phage' integrase family K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 379.0
HKD1_k127_6973198_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000007965 256.0
HKD1_k127_6973198_2 Lysin motif - - - 0.0000000000003594 73.0
HKD1_k127_699137_0 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000001347 216.0
HKD1_k127_702554_0 Permease K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001234 282.0
HKD1_k127_702554_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000007149 213.0
HKD1_k127_702554_2 - - - - 0.00000000000000000000000000000000006108 141.0
HKD1_k127_7027003_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 K04041 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 497.0
HKD1_k127_7027003_1 hmm pf02588 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005933 269.0
HKD1_k127_7030269_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 447.0
HKD1_k127_7030832_0 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 367.0
HKD1_k127_7030832_1 - - - - 0.00000000000000000001275 92.0
HKD1_k127_7037753_0 Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000009595 179.0
HKD1_k127_7037753_1 Cold-shock protein K03704 - - 0.00000000000000000000000000000002127 126.0
HKD1_k127_7052464_0 Psort location Cytoplasmic, score K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 505.0
HKD1_k127_7052464_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 447.0
HKD1_k127_7052464_2 - - - - 0.0000000000000000000000000000000000000000000000001522 179.0
HKD1_k127_7054164_0 transporter K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 359.0
HKD1_k127_7054164_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008307 272.0
HKD1_k127_7054164_2 Belongs to the 5'-nucleotidase family K01081,K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000002121 100.0
HKD1_k127_7054164_3 Biofilm formation stimulator VEG - - - 0.0000000000002213 73.0
HKD1_k127_7055190_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 317.0
HKD1_k127_7055190_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000648 261.0
HKD1_k127_7069392_0 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 492.0
HKD1_k127_7069392_1 Protein of unknown function (DUF1445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 388.0
HKD1_k127_7069392_2 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 384.0
HKD1_k127_7069392_3 Allophanate hydrolase subunit 1 K06351 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 300.0
HKD1_k127_7069392_4 Thioesterase - - - 0.000000000000000007542 89.0
HKD1_k127_7069392_5 - - - - 0.000008774 49.0
HKD1_k127_7070607_0 L-serine dehydratase, iron-sulfur-dependent, alpha subunit K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 332.0
HKD1_k127_7070607_1 Putative, 10TM heavy-metal exporter K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000001589 233.0
HKD1_k127_7070607_2 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000001371 151.0
HKD1_k127_7070762_0 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000001055 140.0
HKD1_k127_7070762_1 glutaredoxin-like protein, YruB-family - - - 0.0000000000000000000000001235 108.0
HKD1_k127_7074363_0 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 395.0
HKD1_k127_7074363_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000008184 253.0
HKD1_k127_7074363_2 Acetyltransferase GNAT family - - - 0.000000000000000000000000133 106.0
HKD1_k127_7083646_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008348 274.0
HKD1_k127_7083646_1 inosine-uridine preferring nucleoside hydrolase K01239,K01250,K12700 - 3.2.2.1 0.00000000000000000000000000000000000000002061 156.0
HKD1_k127_7101482_0 5-bromo-4-chloroindolyl phosphate hydrolysis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 309.0
HKD1_k127_7101482_1 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000287 168.0
HKD1_k127_7101482_2 PFAM Uncharacterised ACR, YkgG family COG1556 - - - 0.000000000000201 70.0
HKD1_k127_7104546_0 Fibronectin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 428.0
HKD1_k127_7118533_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 290.0
HKD1_k127_7118533_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000005922 70.0
HKD1_k127_713397_0 Mate efflux family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 619.0
HKD1_k127_713397_1 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 294.0
HKD1_k127_713397_2 Putative ABC-transporter type IV - - - 0.000000000000000000000000000004225 121.0
HKD1_k127_7135851_0 S-layer homology domain - - - 0.0000000000000000000000000000000000000000000927 177.0
HKD1_k127_7135851_1 peptidoglycan binding domain protein - - - 0.0000004722 51.0
HKD1_k127_7142306_0 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 325.0
HKD1_k127_7142306_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000007261 190.0
HKD1_k127_7154034_0 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 503.0
HKD1_k127_7161054_0 ATP synthase alpha/beta family, nucleotide-binding domain K02412,K03224 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 531.0
HKD1_k127_7161054_1 bacterial-type flagellum organization K02411 - - 0.00000000000000000000000004819 115.0
HKD1_k127_7167653_0 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000001105 268.0
HKD1_k127_7167653_1 S-layer homology domain - - - 0.00000000000000000001125 101.0
HKD1_k127_7169078_0 PFAM copper amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000003798 228.0
HKD1_k127_7169078_1 NADPH-dependent FMN reductase - - - 0.00000007674 53.0
HKD1_k127_717825_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006944 228.0
HKD1_k127_717825_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000001987 200.0
HKD1_k127_717825_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000006833 174.0
HKD1_k127_717825_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000006735 97.0
HKD1_k127_717825_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0003645 49.0
HKD1_k127_7180925_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 327.0
HKD1_k127_7184052_0 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 364.0
HKD1_k127_7195431_0 Radical SAM-linked protein - - - 0.000000000000000000000000000000000000001409 155.0
HKD1_k127_7195431_1 ribonuclease, Rne Rng family K08301 - - 0.00000000000000000000001878 103.0
HKD1_k127_7216065_0 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 474.0
HKD1_k127_7216065_1 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000002055 184.0
HKD1_k127_7219404_0 Methyltransferase K10218 - 4.1.3.17 0.000000000000000000000000000000000000000014 161.0
HKD1_k127_7219404_1 PFAM Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000002096 138.0
HKD1_k127_7227478_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 6.611e-196 621.0
HKD1_k127_7227478_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000001697 118.0
HKD1_k127_7231088_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 3.64e-240 745.0
HKD1_k127_7231088_1 PFAM SNARE associated Golgi protein K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 501.0
HKD1_k127_7231088_2 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K14205 - 2.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 445.0
HKD1_k127_7239388_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.264e-200 651.0
HKD1_k127_7239388_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000004353 179.0
HKD1_k127_7239388_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000008307 117.0
HKD1_k127_7247798_0 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 426.0
HKD1_k127_7247798_1 carbon dioxide binding K04653,K04654 - - 0.0000000000000000000000003871 105.0
HKD1_k127_7293902_0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 407.0
HKD1_k127_7293902_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 361.0
HKD1_k127_7293902_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002321 242.0
HKD1_k127_7293902_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000002806 153.0
HKD1_k127_7312956_0 DegV family - - - 0.0000000000000000000000000000000000000000002731 162.0
HKD1_k127_7312956_1 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.00000000000000000000000000000000000000271 150.0
HKD1_k127_7312956_2 Excinuclease ABC C subunit domain protein K07461 - - 0.00000000000000000000000000007321 117.0
HKD1_k127_7317884_0 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 317.0
HKD1_k127_7317884_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000001633 206.0
HKD1_k127_7317884_2 Catalyzes the carbon skeleton rearrangement of L- glutamate to L-threo-3-methylaspartate ((2S,3S)-3- methylaspartate) K01846 - 5.4.99.1 0.00000000000000000000000000000000000000000007836 166.0
HKD1_k127_73205_0 Abc transporter K02056 - 3.6.3.17 5.832e-234 730.0
HKD1_k127_73205_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 319.0
HKD1_k127_7337516_0 ABC transporter K06147 - - 2.633e-222 704.0
HKD1_k127_7337516_1 ABC transporter K06147 - - 0.0000000000000000005994 89.0
HKD1_k127_7337545_0 Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009766 244.0
HKD1_k127_7337545_1 stage III sporulation protein AA K06390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002974 247.0
HKD1_k127_7341484_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 424.0
HKD1_k127_7341484_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000005764 123.0
HKD1_k127_7352372_0 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 409.0
HKD1_k127_7352372_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 386.0
HKD1_k127_7352372_2 Stage II sporulation E family protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 359.0
HKD1_k127_7352372_3 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 342.0
HKD1_k127_7352372_4 DNA polymerase alpha chain like domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008153 256.0
HKD1_k127_7352372_5 amidohydrolase - - - 0.00000000000000000000000000000000000007597 144.0
HKD1_k127_7357183_0 Histidine kinase - - - 2.602e-225 725.0
HKD1_k127_7357183_1 NADH flavin oxidoreductase NADH oxidase K10797 - 1.3.1.31 0.00000000000000000000000000001767 119.0
HKD1_k127_7372860_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 563.0
HKD1_k127_7372860_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 326.0
HKD1_k127_7376341_0 xanthine dehydrogenase activity K00087 - 1.17.1.4 1.076e-301 944.0
HKD1_k127_7376341_1 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 319.0
HKD1_k127_7376341_2 2 iron, 2 sulfur cluster binding K03518,K07302 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000005992 243.0
HKD1_k127_7376341_3 enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000002215 216.0
HKD1_k127_7376341_4 enoyl-CoA hydratase isomerase family - - - 0.00000000000000000002884 92.0
HKD1_k127_7377493_0 Iron hydrogenase small subunit K00336,K18332 - 1.12.1.3,1.6.5.3 1.337e-275 857.0
HKD1_k127_7377493_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 411.0
HKD1_k127_7382198_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 405.0
HKD1_k127_7382198_1 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.000000000000000000000000000000000000000000000000000000000000000000003488 235.0
HKD1_k127_7382198_2 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000003482 146.0
HKD1_k127_7410875_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 378.0
HKD1_k127_7413088_0 Permease K02824 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 567.0
HKD1_k127_7415009_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 3.726e-194 616.0
HKD1_k127_7416157_0 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 496.0
HKD1_k127_7416157_1 ECF-type riboflavin transporter, S component - - - 0.000000000000000000000000000000000000008126 151.0
HKD1_k127_7418386_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 318.0
HKD1_k127_7418386_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000001051 230.0
HKD1_k127_7418386_2 ABC transporter, substrate-binding protein, family 5 K02035 - - 0.000000000000000000207 91.0
HKD1_k127_7428726_0 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 1.961e-194 611.0
HKD1_k127_7428726_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000008952 174.0
HKD1_k127_7445437_0 Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006759 469.0
HKD1_k127_7445437_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001832 267.0
HKD1_k127_7445437_2 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000001203 232.0
HKD1_k127_7448459_0 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 310.0
HKD1_k127_7448459_1 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000002249 129.0
HKD1_k127_746039_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009254 470.0
HKD1_k127_746039_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001353 274.0
HKD1_k127_746039_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000659 233.0
HKD1_k127_746039_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000003963 156.0
HKD1_k127_746039_4 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000002561 93.0
HKD1_k127_746039_5 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000004487 65.0
HKD1_k127_7465932_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 314.0
HKD1_k127_7465932_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.00000000000000000000000002376 108.0
HKD1_k127_7466807_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000001667 176.0
HKD1_k127_7466807_1 Transcriptional regulator K03724,K15545 - - 0.000000000000000000000000003706 118.0
HKD1_k127_7466807_2 PFAM BFD domain protein 2Fe-2S -binding domain protein - - - 0.000003214 49.0
HKD1_k127_7470088_0 cadmium-exporting ATPase K01534 - 3.6.3.3,3.6.3.5 1.718e-209 657.0
HKD1_k127_7470088_1 cadmium-exporting ATPase K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 289.0
HKD1_k127_7470088_2 PFAM Bacterial regulatory protein, arsR family K21903 - - 0.00000000000000000000000000000000000000000000000000000000003443 206.0
HKD1_k127_7470088_3 Lysine exporter LysO - - - 0.000000000000000000000000000000000000000000000000001574 188.0
HKD1_k127_7470088_4 Belongs to the phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000001321 157.0
HKD1_k127_7470088_5 Heavy-metal-associated domain - - - 0.000000000000000000000000003441 112.0
HKD1_k127_7470088_6 - - - - 0.000000003532 62.0
HKD1_k127_7482096_0 Bacterial export proteins, family 1 K02421,K03228,K13820 - - 0.000000000000000000000000000000000000000000000000000000152 203.0
HKD1_k127_7482096_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401,K03229,K04061,K13820,K22510 - - 0.000000000000000000000000000000000000001284 154.0
HKD1_k127_7482096_2 Bacterial export proteins, family 3 K02420 - - 0.000000000000004649 75.0
HKD1_k127_7504656_0 NADH flavin oxidoreductase NADH oxidase K10797 - 1.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 481.0
HKD1_k127_7506326_0 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 506.0
HKD1_k127_7506326_1 Outer membrane efflux protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 362.0
HKD1_k127_7506326_2 ABC transporter K01990 - - 0.000000000000000000000000000007275 118.0
HKD1_k127_7513509_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 510.0
HKD1_k127_7513509_1 Sporulation and spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000002132 251.0
HKD1_k127_7513509_2 PFAM Manganese containing catalase K07217 - - 0.00002976 46.0
HKD1_k127_7520215_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 421.0
HKD1_k127_7520215_1 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000001278 205.0
HKD1_k127_7520215_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000002979 171.0
HKD1_k127_7520215_3 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.000000000000000000000000000000000000000006391 160.0
HKD1_k127_7520215_4 negative regulation of DNA recombination - - - 0.0000000000000000000000000000000000001173 146.0
HKD1_k127_7526198_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 437.0
HKD1_k127_7526198_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.000000000000000000000000002276 112.0
HKD1_k127_7527593_0 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 291.0
HKD1_k127_7527593_1 uridine kinase K00876 - 2.7.1.48 0.00000000000000000000004192 104.0
HKD1_k127_7527850_0 PFAM Transposase DDE domain - - - 0.00000000000000000000000001916 108.0
HKD1_k127_7528983_0 methyl-accepting chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 474.0
HKD1_k127_7528983_1 amino acid carrier protein K03310 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 358.0
HKD1_k127_7528983_2 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 344.0
HKD1_k127_7530262_0 Inorganic pyrophosphatase K15986 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 396.0
HKD1_k127_7530262_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000002206 239.0
HKD1_k127_7530303_0 extracellular solute-binding protein, family 7 K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001038 259.0
HKD1_k127_7530303_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000008191 213.0
HKD1_k127_7530303_2 PFAM Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000000000000000000000000000000000002613 154.0
HKD1_k127_7533040_0 Thymidylate synthase K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 456.0
HKD1_k127_7533040_1 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000004896 175.0
HKD1_k127_7533060_0 molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005236 264.0
HKD1_k127_7533060_1 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000000001249 200.0
HKD1_k127_7537450_0 family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 416.0
HKD1_k127_7537450_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 369.0
HKD1_k127_7537450_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 331.0
HKD1_k127_7538584_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 398.0
HKD1_k127_7538584_1 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein K09787 - - 0.00000000000000000002254 95.0
HKD1_k127_7542926_0 transporter, DctM subunit K21393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 381.0
HKD1_k127_7542926_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000004801 259.0
HKD1_k127_7542926_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000006381 226.0
HKD1_k127_7542926_3 carbohydrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000308 230.0
HKD1_k127_7542926_4 Trap-type c4-dicarboxylate transport system, small permease component K11689,K21394 - - 0.0000000000000000002299 94.0
HKD1_k127_7565751_0 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.00000000000000000000000000000000000000001814 156.0
HKD1_k127_7565751_1 Putative rRNA methylase - - - 0.00000000000000000000000000000000000003909 149.0
HKD1_k127_7566465_0 amino acid carrier protein K03310 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 475.0
HKD1_k127_7566465_1 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 428.0
HKD1_k127_7572171_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 331.0
HKD1_k127_7572171_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008498 267.0
HKD1_k127_7572171_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000003347 214.0
HKD1_k127_7572852_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 580.0
HKD1_k127_7572852_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 579.0
HKD1_k127_7572852_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 390.0
HKD1_k127_7572852_3 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 386.0
HKD1_k127_7573991_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.6e-309 953.0
HKD1_k127_7575267_0 EcsC protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 299.0
HKD1_k127_7575267_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000358 63.0
HKD1_k127_7576960_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 557.0
HKD1_k127_7576960_1 Arginine dihydrolase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 440.0
HKD1_k127_7583714_0 TIGRFAM UbiD family decarboxylases K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 514.0
HKD1_k127_7583714_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000004905 256.0
HKD1_k127_7583714_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000001212 184.0
HKD1_k127_7583838_0 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 314.0
HKD1_k127_7583838_1 FecCD transport family K02015 - - 0.0000000000000000000000000000000000000000000006227 167.0
HKD1_k127_7583838_2 Diphthamide synthase - - - 0.00000000000000000012 89.0
HKD1_k127_7594165_0 overlaps another CDS with the same product name - - - 1.2e-202 639.0
HKD1_k127_7594165_1 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 456.0
HKD1_k127_7594165_2 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000002309 213.0
HKD1_k127_7594165_3 Radical SAM domain protein - - - 0.0000000000000000000001528 99.0
HKD1_k127_7608593_0 Psort location Cytoplasmic, score 8.87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 486.0
HKD1_k127_7620578_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1473.0
HKD1_k127_7620578_1 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000003421 175.0
HKD1_k127_7630241_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 420.0
HKD1_k127_7630241_1 Histidine biosynthesis protein K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008436 321.0
HKD1_k127_7630241_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001729 261.0
HKD1_k127_7630241_3 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000195 86.0
HKD1_k127_7630480_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002853 236.0
HKD1_k127_7630480_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000002202 209.0
HKD1_k127_7630480_2 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000000001635 140.0
HKD1_k127_7636171_0 tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001303 267.0
HKD1_k127_7636171_1 Belongs to the BI1 family K06890 - - 0.000000000000000000000000000000007516 136.0
HKD1_k127_7650311_0 the current gene model (or a revised gene model) may contain a frame shift K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 517.0
HKD1_k127_7650311_1 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 332.0
HKD1_k127_7650311_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001195 250.0
HKD1_k127_7650311_3 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000001666 78.0
HKD1_k127_7650311_4 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000114 47.0
HKD1_k127_7651242_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 462.0
HKD1_k127_7651242_1 Sporulation protein YyaC - - - 0.0000000000000000000000000000000000000001855 154.0
HKD1_k127_7670011_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 462.0
HKD1_k127_7670011_1 Belongs to the D-alanine--D-alanine ligase family - - - 0.0000000000000000000000000000000000000000000000000000000002874 206.0
HKD1_k127_7678281_0 N-4 methylation of cytosine K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 401.0
HKD1_k127_7678281_1 Menaquinone biosynthesis K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 299.0
HKD1_k127_7678281_2 MjaI restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000004125 239.0
HKD1_k127_7678281_3 Iron-only hydrogenase system regulator - - - 0.00000000000000000000000000002271 118.0
HKD1_k127_7678281_4 Helix-turn-helix XRE-family like proteins - - - 0.00001442 49.0
HKD1_k127_7680635_0 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 443.0
HKD1_k127_7680635_1 Psort location Cytoplasmic, score 8.87 K00899 - 2.7.1.100 0.000000000000000000000000000000000000000000000000000000000000000005551 235.0
HKD1_k127_7697384_0 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000008969 199.0
HKD1_k127_7697457_0 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 475.0
HKD1_k127_7697457_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001149 275.0
HKD1_k127_7718445_0 PFAM Transposase, Mutator - - - 6.738e-227 706.0
HKD1_k127_7718740_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 301.0
HKD1_k127_7718740_1 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 280.0
HKD1_k127_7721311_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005301 273.0
HKD1_k127_7721311_1 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000003329 138.0
HKD1_k127_7726305_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000007958 255.0
HKD1_k127_7726305_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 - - 0.000000000000000000000000000000000000000000003594 166.0
HKD1_k127_7729093_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000001503 214.0
HKD1_k127_7729093_1 HutD - - - 0.00000000000000000000000000000000000000000001118 169.0
HKD1_k127_773359_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 574.0
HKD1_k127_773359_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00651 - 2.3.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000005907 259.0
HKD1_k127_7755984_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 1.703e-241 759.0
HKD1_k127_7755984_1 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000002114 163.0
HKD1_k127_7755984_2 NusG domain II - - - 0.00000000000000000001061 96.0
HKD1_k127_7756222_0 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02342,K03763 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004705 284.0
HKD1_k127_7808011_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000001479 219.0
HKD1_k127_7808011_1 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000001087 89.0
HKD1_k127_7808011_2 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0004424 45.0
HKD1_k127_7811118_0 ABC transporter K02056 - 3.6.3.17 5.21e-213 666.0
HKD1_k127_7811118_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 584.0
HKD1_k127_7811118_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 529.0
HKD1_k127_7811118_3 PucR C-terminal helix-turn-helix domain K09684 - - 0.000000000002419 70.0
HKD1_k127_7816133_0 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 514.0
HKD1_k127_7816133_1 Flavodoxin K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000108 214.0
HKD1_k127_7816133_2 DegV family - - - 0.00000000000000002588 81.0
HKD1_k127_7821192_0 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 429.0
HKD1_k127_7821192_1 Psort location K03546 - - 0.000000000000000000000000000000000000000000000000000000002293 208.0
HKD1_k127_7822624_0 plasmid maintenance K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 336.0
HKD1_k127_7822624_1 chemotaxis K03408 - - 0.000000000000000000000000000000000000000000000000000006061 194.0
HKD1_k127_7822624_2 Late competence development protein ComFB - - - 0.00000000000000000000004159 104.0
HKD1_k127_7828581_0 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005705 258.0
HKD1_k127_7828581_1 Integral membrane sensor signal transduction histidine kinase K07680,K07778,K11617,K14988 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000006958 225.0
HKD1_k127_7828581_2 FAD binding domain - - - 0.000000000000000000000000001651 117.0
HKD1_k127_7834975_0 response to heat K03694,K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 353.0
HKD1_k127_7834975_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003925 252.0
HKD1_k127_7847433_0 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000001458 224.0
HKD1_k127_7847433_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000001144 192.0
HKD1_k127_7847433_2 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000009241 171.0
HKD1_k127_7847433_3 Protein of unknown function (DUF1294) - - - 0.00000003183 56.0
HKD1_k127_7850708_0 Polysaccharide biosynthesis C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 601.0
HKD1_k127_7850708_1 Psort location CytoplasmicMembrane, score 10.00 K06147 - - 0.0000000000000000000000000000000000000000000002254 168.0
HKD1_k127_7850708_2 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000000000000000000003073 162.0
HKD1_k127_7850708_3 GCN5-related N-acetyl-transferase K06975 - - 0.000003394 49.0
HKD1_k127_7859443_0 elongation factor G - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003555 276.0
HKD1_k127_7863174_0 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 361.0
HKD1_k127_7863174_1 tRNA wobble cytosine modification - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003883 245.0
HKD1_k127_7863174_2 transcriptional regulatory protein K02475,K11615,K11692,K11712 - - 0.00000000000000000000000000000000000000009362 152.0
HKD1_k127_7868547_0 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000006996 237.0
HKD1_k127_7868547_1 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000001003 200.0
HKD1_k127_7868547_2 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000003489 85.0
HKD1_k127_7869088_0 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001404 250.0
HKD1_k127_7869088_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000001011 159.0
HKD1_k127_7869088_2 MOSC domain containing protein - - - 0.00004487 45.0
HKD1_k127_7878598_0 Belongs to the sulfur carrier protein TusA family - - - 1.311e-303 937.0
HKD1_k127_7878598_1 TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 443.0
HKD1_k127_7878598_2 domain protein - - - 0.00000000000000000000000000000000000000000001124 164.0
HKD1_k127_7914811_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1229.0
HKD1_k127_7936171_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 7.695e-254 788.0
HKD1_k127_7936171_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 423.0
HKD1_k127_7936171_2 Belongs to the P(II) protein family K03320 - - 0.0005102 43.0
HKD1_k127_7944945_0 PFAM Amino acid K16238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 301.0
HKD1_k127_7944945_1 MmgE PrpD family protein - - - 0.0000000000000000000004817 99.0
HKD1_k127_7951181_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 467.0
HKD1_k127_7951181_1 Malate/L-lactate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009781 298.0
HKD1_k127_7951181_2 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002048 274.0
HKD1_k127_7951181_3 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000004691 158.0
HKD1_k127_7951181_4 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000001704 96.0
HKD1_k127_7964276_0 Staygreen protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 406.0
HKD1_k127_7964276_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 320.0
HKD1_k127_7964276_2 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000001986 181.0
HKD1_k127_7964276_3 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000002686 153.0
HKD1_k127_7973340_0 Domain of unknown function (DUF4153) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 370.0
HKD1_k127_7973340_1 DegV family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 311.0
HKD1_k127_7973340_2 SNARE associated Golgi protein K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000004447 205.0
HKD1_k127_7973340_3 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000004608 196.0
HKD1_k127_7981614_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 428.0
HKD1_k127_7981614_1 Domain of unknown function (DUF4474) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 308.0
HKD1_k127_7989449_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 1.911e-229 724.0
HKD1_k127_7989449_1 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001514 261.0
HKD1_k127_799047_0 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 404.0
HKD1_k127_799047_1 Acetylglutamate kinase - - - 0.00002068 48.0
HKD1_k127_7992586_0 PFAM sigma-54 factor interaction domain-containing protein K02688 - - 5.41e-247 777.0
HKD1_k127_7992586_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 330.0
HKD1_k127_7992586_2 COG2610 H gluconate symporter and related permeases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 322.0
HKD1_k127_8002512_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 447.0
HKD1_k127_8002512_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000005653 192.0
HKD1_k127_8002512_2 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000002726 174.0
HKD1_k127_8005189_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 544.0
HKD1_k127_8005189_1 aldo keto reductase family K07079 - - 0.0000000000001305 71.0
HKD1_k127_8014658_0 Calcineurin-like phosphoesterase - - - 1.29e-198 626.0
HKD1_k127_8025965_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 3.785e-255 792.0
HKD1_k127_8025965_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 522.0
HKD1_k127_8025965_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 432.0
HKD1_k127_8025965_3 Deoxyguanosinetriphosphate triphosphohydrolase K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 417.0
HKD1_k127_8025965_4 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 329.0
HKD1_k127_8025965_5 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001189 235.0
HKD1_k127_8025965_6 SAM-dependent methyltransferase K06967 - 2.1.1.217 0.000000000000000000000000000000000000003207 150.0
HKD1_k127_8025965_7 UBA TS-N domain - - - 0.0000000000005139 73.0
HKD1_k127_802851_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000003471 189.0
HKD1_k127_802851_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000614 160.0
HKD1_k127_8029414_0 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 291.0
HKD1_k127_8029414_1 cytochrome c biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000008996 135.0
HKD1_k127_8035883_0 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 319.0
HKD1_k127_8035883_1 PFAM transposase, mutator K07493 - - 0.0004293 44.0
HKD1_k127_8036137_0 synthase K01654 - 2.5.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 305.0
HKD1_k127_8036137_1 Cytidylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 306.0
HKD1_k127_815657_0 COG4880 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 385.0
HKD1_k127_841571_0 - - - - 0.000000000000000000000000000000008808 135.0
HKD1_k127_841571_1 heme binding K00759 - 2.4.2.7 0.0000000000000005422 89.0
HKD1_k127_847122_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.159e-263 820.0
HKD1_k127_847122_1 LysM domain - - - 0.00000000000000000000000000006553 128.0
HKD1_k127_866359_0 ABC transporter K06158 - - 0.00000000000000000000000000000000136 133.0
HKD1_k127_866359_1 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000008669 83.0
HKD1_k127_868175_0 helicase superfamily c-terminal domain K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 438.0
HKD1_k127_868175_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003485 231.0
HKD1_k127_868175_2 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000001073 85.0
HKD1_k127_8767_0 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 575.0
HKD1_k127_8767_1 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 462.0
HKD1_k127_8767_2 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 339.0
HKD1_k127_8946_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 550.0
HKD1_k127_8946_1 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 464.0
HKD1_k127_8946_2 Peptidase family M20/M25/M40 - - - 0.00000000000000000000000000000000000001817 149.0
HKD1_k127_89512_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000002257 256.0
HKD1_k127_89512_1 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000002686 180.0
HKD1_k127_89512_2 conserved protein (DUF2156) K01163 - - 0.000000006421 67.0
HKD1_k127_89512_3 - - - - 0.00000001373 58.0
HKD1_k127_93102_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 5.695e-215 670.0
HKD1_k127_93102_1 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003612 265.0
HKD1_k127_93102_2 4 iron, 4 sulfur cluster binding K18356 - 1.2.1.58 0.00000000000000000000000000000000000000000000000000003623 189.0
HKD1_k127_935224_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 324.0
HKD1_k127_935224_1 ATP synthase subunit C K02124 - - 0.00000000000000000000000000000000000000000000000000000000001226 210.0
HKD1_k127_935224_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000002432 184.0
HKD1_k127_936628_0 flavin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 372.0
HKD1_k127_936628_1 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 298.0
HKD1_k127_971141_0 Belongs to the UPF0348 family - - - 0.00000000000000000000000000000001439 138.0
HKD1_k127_971141_1 Sporulation integral membrane protein YlbJ - - - 0.0000181 55.0
HKD1_k127_98331_0 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 502.0
HKD1_k127_98331_1 FAD dependent oxidoreductase K00302 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 486.0
HKD1_k127_98331_2 domain protein K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 458.0
HKD1_k127_98331_3 potassium uptake protein TrkH K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 443.0
HKD1_k127_98331_4 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000003548 197.0
HKD1_k127_98331_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000001103 173.0
HKD1_k127_98331_6 BFD-like [2Fe-2S] binding domain - - - 0.000000000000000000000000000386 115.0