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Overview

ID MAG01771
Name HKD2_bin.100
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Myxococcota
Class Polyangia
Order Polyangiales
Family Polyangiaceae
Genus DASXHD01
Species
Assembly information
Completeness (%) 78.66
Contamination (%) 5.14
GC content (%) 69.0
N50 (bp) 8,958
Genome size (bp) 6,823,699

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes5364

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10020518_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 454.0
HKD2_k127_10020518_1 Pyruvate dehydrogenase K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 421.0
HKD2_k127_10020518_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 381.0
HKD2_k127_10020518_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 299.0
HKD2_k127_10020518_4 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003767 250.0
HKD2_k127_10024974_0 Family membership - - - 7.285e-249 813.0
HKD2_k127_10024974_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 574.0
HKD2_k127_10024974_2 Uncharacterised protein family (UPF0158) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 316.0
HKD2_k127_10024974_4 alpha-ribazole phosphatase activity K01834,K15634,K22306 - 3.1.3.85,5.4.2.11,5.4.2.12 0.0000000000000000000000000000000000004824 146.0
HKD2_k127_10024974_5 belongs to the thioredoxin family K03671 - - 0.00000000000000000000000004887 110.0
HKD2_k127_10024974_6 Sigma-70, region 4 K03088 - - 0.0000000000000000008764 95.0
HKD2_k127_10044691_0 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005993 271.0
HKD2_k127_10044691_1 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000003183 267.0
HKD2_k127_10044691_2 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000001038 167.0
HKD2_k127_10044691_3 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000001234 73.0
HKD2_k127_10046961_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 3.851e-280 886.0
HKD2_k127_10046961_1 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 497.0
HKD2_k127_10046961_2 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 308.0
HKD2_k127_10046961_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484 - 2.7.13.3 0.000000000001617 70.0
HKD2_k127_10046961_4 Prokaryotic N-terminal methylation motif K02650 - - 0.00000000002857 76.0
HKD2_k127_10113504_0 DUF1704 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 599.0
HKD2_k127_10113504_1 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 342.0
HKD2_k127_10113504_2 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 338.0
HKD2_k127_10113504_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002474 293.0
HKD2_k127_10113504_4 - - - - 0.00000000000000000000000000000000000000001057 154.0
HKD2_k127_10113504_5 pyrroloquinoline quinone binding - - - 0.00000000636 67.0
HKD2_k127_10113504_6 Involved in the tonB-independent uptake of proteins - - - 0.00000886 48.0
HKD2_k127_10128258_0 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 345.0
HKD2_k127_10128258_1 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000004963 156.0
HKD2_k127_10128258_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000004092 151.0
HKD2_k127_10128258_3 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000003391 140.0
HKD2_k127_10168893_0 acyl-coa dehydrogenase - - - 4.555e-203 639.0
HKD2_k127_10168893_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 534.0
HKD2_k127_10168893_2 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002736 284.0
HKD2_k127_10168893_3 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.00000000000000000000000000000000000000004682 154.0
HKD2_k127_10168893_4 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000004316 146.0
HKD2_k127_10168893_5 Pfam:RRM_6 - - - 0.00000000000000000000000000007874 124.0
HKD2_k127_10178839_0 ABC transporter permease K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 306.0
HKD2_k127_10178839_1 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000288 222.0
HKD2_k127_10178839_2 - - - - 0.00000000000000000000000000000000000000001977 158.0
HKD2_k127_10178839_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000064 63.0
HKD2_k127_10198270_0 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 310.0
HKD2_k127_10198270_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000126 156.0
HKD2_k127_10200101_0 Sulfatase-modifying factor enzyme 1 K08884,K12132 - 2.7.11.1 6.449e-301 946.0
HKD2_k127_10200101_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 526.0
HKD2_k127_1026656_0 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 421.0
HKD2_k127_1030567_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000006951 201.0
HKD2_k127_1030567_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000005938 177.0
HKD2_k127_1030567_3 membrane organization - - - 0.000000000000000000000000000000001124 147.0
HKD2_k127_1030567_5 metallopeptidase activity K01179 - 3.2.1.4 0.000001104 50.0
HKD2_k127_1036390_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 478.0
HKD2_k127_1036390_1 high-affinity sulfate:proton symporter activity K06203 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600 - 0.000000000000000000000000000000000000000002102 166.0
HKD2_k127_1036390_2 - - - - 0.00008526 56.0
HKD2_k127_104236_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 5.537e-203 651.0
HKD2_k127_104236_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 477.0
HKD2_k127_104236_10 - - - - 0.0000000000000000000000000000000000000000000000005696 183.0
HKD2_k127_104236_11 PFAM PHA accumulation regulator DNA-binding protein - - - 0.0000000000000000000000000000000000002441 146.0
HKD2_k127_104236_12 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000009305 156.0
HKD2_k127_104236_13 - - - - 0.00000000000000000000002128 104.0
HKD2_k127_104236_14 Activator of Hsp90 ATPase - - - 0.000000000000000000001092 103.0
HKD2_k127_104236_15 pyrroloquinoline quinone binding - - - 0.000003416 59.0
HKD2_k127_104236_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 384.0
HKD2_k127_104236_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 318.0
HKD2_k127_104236_4 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002493 259.0
HKD2_k127_104236_5 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009347 252.0
HKD2_k127_104236_6 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000004929 222.0
HKD2_k127_104236_7 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate - - - 0.0000000000000000000000000000000000000000000000000000000006048 210.0
HKD2_k127_104236_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000002726 216.0
HKD2_k127_104236_9 - - - - 0.00000000000000000000000000000000000000000000000002518 205.0
HKD2_k127_1044015_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 433.0
HKD2_k127_1044015_1 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009054 269.0
HKD2_k127_1044015_2 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000002288 136.0
HKD2_k127_1044015_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000004241 69.0
HKD2_k127_1044015_4 Domain of unknown function (DUF5122) beta-propeller - - - 0.00003169 57.0
HKD2_k127_1075912_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 475.0
HKD2_k127_1075912_1 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 317.0
HKD2_k127_1075912_2 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000823 92.0
HKD2_k127_1075912_3 amine dehydrogenase activity - - - 0.00000000000000007695 94.0
HKD2_k127_109589_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000005458 216.0
HKD2_k127_109589_1 PFAM Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000000000000000000000000412 204.0
HKD2_k127_1115375_0 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 295.0
HKD2_k127_1115375_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001012 254.0
HKD2_k127_1115375_3 - - - - 0.00000000000000000000000000000007154 133.0
HKD2_k127_1198671_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 351.0
HKD2_k127_1198671_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 349.0
HKD2_k127_1198671_3 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000007011 154.0
HKD2_k127_1216572_0 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 7.013e-257 804.0
HKD2_k127_1216572_1 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000001237 104.0
HKD2_k127_123449_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 560.0
HKD2_k127_123449_2 Glutathione S-transferase, C-terminal domain K07393 - 1.8.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 398.0
HKD2_k127_123449_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 324.0
HKD2_k127_123449_4 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 302.0
HKD2_k127_123449_5 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000006915 246.0
HKD2_k127_123449_6 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000003247 64.0
HKD2_k127_1241530_0 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 412.0
HKD2_k127_1241530_1 - - - - 0.00000000000000000000000000000000000000000000000000000001969 209.0
HKD2_k127_1241530_2 protein kinase activity - - - 0.00000000000000000000000000000009056 133.0
HKD2_k127_127287_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004382 285.0
HKD2_k127_127287_1 acetyltransferase - - - 0.0000000000000000000006602 108.0
HKD2_k127_127287_2 Transcriptional regulator - - - 0.00000000000000001301 85.0
HKD2_k127_1288281_0 FtsX-like permease family K02004 - - 1.219e-207 676.0
HKD2_k127_1288281_1 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 320.0
HKD2_k127_1288281_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004293 258.0
HKD2_k127_1288281_3 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000002709 198.0
HKD2_k127_1288281_5 AI-2E family transporter - - - 0.000000000000000000000002248 117.0
HKD2_k127_1288281_7 Belongs to the thioredoxin family K03671 - - 0.00000000001564 65.0
HKD2_k127_1288281_8 Putative modulator of DNA gyrase - - - 0.0005346 44.0
HKD2_k127_1288314_0 beta-lactamase - - - 1.358e-221 710.0
HKD2_k127_1288314_1 - - - - 0.00000000000000000000000000000000000000000000000000005818 205.0
HKD2_k127_129642_0 Family membership - - - 1.09e-205 684.0
HKD2_k127_129642_1 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 484.0
HKD2_k127_129642_2 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 404.0
HKD2_k127_129642_3 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 418.0
HKD2_k127_129642_4 UDP-glucoronosyl and UDP-glucosyl transferase K05841 - 2.4.1.173 0.000000000000000000000000000000000000000000000000000000000000000000000000003146 269.0
HKD2_k127_129642_5 Family membership K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001236 247.0
HKD2_k127_129642_6 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000006027 235.0
HKD2_k127_129642_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000008379 240.0
HKD2_k127_129642_8 protein trimerization - - - 0.000000000000000000000000000000000000000004781 174.0
HKD2_k127_129642_9 NmrA-like family K00091 - 1.1.1.219 0.00000000000000000000000002655 127.0
HKD2_k127_1302696_0 Multicopper oxidase K06324 - 1.16.3.3 1.23e-215 690.0
HKD2_k127_1302696_1 amine dehydrogenase activity K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 478.0
HKD2_k127_1302696_2 DbpA RNA binding domain K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 449.0
HKD2_k127_1302696_3 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000008768 206.0
HKD2_k127_1302696_4 Thioredoxin - - - 0.00000000000000000000000003367 109.0
HKD2_k127_1304057_0 Belongs to the BI1 family K06890,K19416 - - 0.0000000000000000000000000000000000000000000000000000000000001269 221.0
HKD2_k127_1304057_1 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000000006611 199.0
HKD2_k127_1304057_2 Rhodanese Homology Domain - - - 0.000000000000000000009981 95.0
HKD2_k127_1304057_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000006438 91.0
HKD2_k127_1305751_0 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 466.0
HKD2_k127_1305751_1 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000002241 249.0
HKD2_k127_1305751_3 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000006793 178.0
HKD2_k127_1305751_4 Belongs to the Fur family K03711,K09825 - - 0.00000000000000000000000000000000000000001695 157.0
HKD2_k127_1307513_0 AAA ATPase domain - - - 1.577e-235 774.0
HKD2_k127_1307513_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 2.158e-195 623.0
HKD2_k127_1307513_2 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 416.0
HKD2_k127_1307513_3 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 329.0
HKD2_k127_1307513_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 292.0
HKD2_k127_1307513_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000003312 191.0
HKD2_k127_1307513_6 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000006084 127.0
HKD2_k127_1307513_7 BolA-like protein - - - 0.00000000000000679 86.0
HKD2_k127_1307513_8 - - - - 0.0000004588 55.0
HKD2_k127_1307513_9 Beta-L-arabinofuranosidase, GH127 - - - 0.00001592 58.0
HKD2_k127_1309865_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 319.0
HKD2_k127_1310757_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 6.772e-194 617.0
HKD2_k127_1310757_1 Proposed nucleic acid binding domain - - - 0.000000000000000009602 98.0
HKD2_k127_1310757_2 Putative zinc- or iron-chelating domain - - - 0.00000000000000001565 93.0
HKD2_k127_1321167_0 Carboxypeptidase regulatory-like domain - - - 3.854e-222 722.0
HKD2_k127_1321167_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 292.0
HKD2_k127_1321167_2 - - - - 0.0000000000000000000000000000000000000000000000000000000008195 213.0
HKD2_k127_1321167_3 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.00000000000000000000000000000000000000000002668 170.0
HKD2_k127_1321167_5 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000002115 145.0
HKD2_k127_1321167_6 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000003685 126.0
HKD2_k127_1326193_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 584.0
HKD2_k127_1326193_1 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 509.0
HKD2_k127_1326193_10 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000657 262.0
HKD2_k127_1326193_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000002652 239.0
HKD2_k127_1326193_12 PFAM Nucleotidyl transferase K00966,K00978,K15669 - 2.7.7.13,2.7.7.33,2.7.7.71 0.0000000000000000000000000000000000000000000000000000000000000003716 227.0
HKD2_k127_1326193_13 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000002785 223.0
HKD2_k127_1326193_14 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000006676 232.0
HKD2_k127_1326193_15 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000005591 197.0
HKD2_k127_1326193_16 NUDIX domain - - - 0.00000000000000000000000000000000000001008 153.0
HKD2_k127_1326193_17 - - - - 0.000000000000000000000000000000001156 144.0
HKD2_k127_1326193_18 PFAM ASPIC and UnbV - - - 0.00000000000000000000000009257 124.0
HKD2_k127_1326193_19 MarR family - - - 0.0000003499 59.0
HKD2_k127_1326193_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 505.0
HKD2_k127_1326193_20 Mannosyltransferase (PIG-V) - - - 0.0000008254 61.0
HKD2_k127_1326193_21 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000001078 62.0
HKD2_k127_1326193_23 RAM signalling pathway protein - GO:0000003,GO:0000131,GO:0000920,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005815,GO:0005816,GO:0005856,GO:0005886,GO:0005933,GO:0005937,GO:0007114,GO:0007117,GO:0007118,GO:0007154,GO:0007165,GO:0008150,GO:0008360,GO:0009987,GO:0015630,GO:0016020,GO:0019954,GO:0022414,GO:0022603,GO:0022604,GO:0023052,GO:0030427,GO:0032153,GO:0032505,GO:0032878,GO:0040007,GO:0042995,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043332,GO:0044422,GO:0044424,GO:0044430,GO:0044446,GO:0044463,GO:0044464,GO:0044732,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051286,GO:0051301,GO:0051716,GO:0061160,GO:0061161,GO:0061172,GO:0061173,GO:0065007,GO:0065008,GO:0071944,GO:0120025,GO:0120038,GO:2000099,GO:2000100,GO:2000114,GO:2000247,GO:2000769,GO:2000771 - 0.000002971 55.0
HKD2_k127_1326193_24 Transcriptional regulator - - - 0.00001226 59.0
HKD2_k127_1326193_25 chitin catabolic process K01233 - 3.2.1.132 0.0003208 52.0
HKD2_k127_1326193_3 PFAM GHMP kinase K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 449.0
HKD2_k127_1326193_4 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 411.0
HKD2_k127_1326193_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 416.0
HKD2_k127_1326193_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000971 401.0
HKD2_k127_1326193_7 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 367.0
HKD2_k127_1326193_8 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 305.0
HKD2_k127_1326193_9 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 295.0
HKD2_k127_1326971_0 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002243 279.0
HKD2_k127_1326971_1 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001826 270.0
HKD2_k127_1326971_2 transporter - - - 0.000000000000000000000000000001543 122.0
HKD2_k127_1328236_0 SMART Elongator protein 3 MiaB NifB - - - 2.111e-263 845.0
HKD2_k127_1328236_1 Aldehyde dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 415.0
HKD2_k127_1328236_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 335.0
HKD2_k127_1328236_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008357 258.0
HKD2_k127_1328236_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000002043 121.0
HKD2_k127_1328236_5 cheY-homologous receiver domain - - - 0.000000000000000000003549 109.0
HKD2_k127_1334955_0 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000004546 168.0
HKD2_k127_1334955_1 Associated with various cellular activities K03924 - - 0.00000000002984 76.0
HKD2_k127_1336364_0 UvrD/REP helicase N-terminal domain - - - 8.508e-318 999.0
HKD2_k127_1337503_0 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000001036 184.0
HKD2_k127_1337503_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000375 74.0
HKD2_k127_1345472_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 367.0
HKD2_k127_1345472_2 - - - - 0.000000000000000000000000000000000000000000000000000000078 216.0
HKD2_k127_1345472_3 Peptidase C26 K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000003239 199.0
HKD2_k127_1345472_5 Major facilitator K08218 - - 0.0000000000000000000000000000000000000000000000472 184.0
HKD2_k127_1351625_0 Acyltransferase family - - - 6.514e-207 661.0
HKD2_k127_1351625_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 512.0
HKD2_k127_1352044_0 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 294.0
HKD2_k127_1352044_1 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000002983 257.0
HKD2_k127_1352044_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000000001597 199.0
HKD2_k127_1352044_3 - - - - 0.000000000000000000000000000000000000000000003577 171.0
HKD2_k127_1352044_4 protein kinase activity - - - 0.00000000000000000000000000000000844 149.0
HKD2_k127_1352516_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 6.362e-286 887.0
HKD2_k127_1362517_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000002422 83.0
HKD2_k127_1366717_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 360.0
HKD2_k127_1366717_1 Cyclic nucleotide-monophosphate binding domain K04739 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001209 287.0
HKD2_k127_1366717_2 Extensin-like protein C-terminus - - - 0.0000000000000000000000000000000000000000000000000001767 193.0
HKD2_k127_1367833_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001278 256.0
HKD2_k127_1367833_1 CAAX protease self-immunity K06177,K07052,K09696 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000006686 169.0
HKD2_k127_1367833_2 Protein of unknown function (DUF2752) - - - 0.000000000000000001241 98.0
HKD2_k127_1367833_3 HB1, ASXL, restriction endonuclease HTH domain - - - 0.00000000007249 67.0
HKD2_k127_1367833_4 Interferon-induced transmembrane protein - - - 0.000006894 55.0
HKD2_k127_1367833_5 Domain of unknown function (DUF4190) - - - 0.0005671 49.0
HKD2_k127_1378566_0 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 434.0
HKD2_k127_1378566_1 PFAM Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 319.0
HKD2_k127_1378566_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001561 255.0
HKD2_k127_1378566_3 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000000000000000005165 131.0
HKD2_k127_1378566_4 Methyltransferase domain - - - 0.0000000000000000000000000007003 117.0
HKD2_k127_1378566_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000000003883 96.0
HKD2_k127_1378566_6 Cupin domain - - - 0.00000000002359 68.0
HKD2_k127_1378566_7 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000005876 59.0
HKD2_k127_1378566_8 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.00001792 57.0
HKD2_k127_1378566_9 AraC-like ligand binding domain - - - 0.00002838 53.0
HKD2_k127_1381490_0 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000007272 250.0
HKD2_k127_1381490_1 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000008774 218.0
HKD2_k127_1381490_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000001172 141.0
HKD2_k127_1381490_3 Mycolic acid cyclopropane synthetase - - - 0.0000001453 53.0
HKD2_k127_1381490_4 MarR family transcriptional regulator - - - 0.0002373 50.0
HKD2_k127_1381982_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 564.0
HKD2_k127_1381982_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 383.0
HKD2_k127_1381982_11 Domain of unknown function (DUF4388) - - - 0.0000000003193 71.0
HKD2_k127_1381982_12 PFAM response regulator receiver K15012 - - 0.000001192 62.0
HKD2_k127_1381982_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 315.0
HKD2_k127_1381982_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008231 279.0
HKD2_k127_1381982_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000002491 243.0
HKD2_k127_1381982_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000001549 229.0
HKD2_k127_1381982_6 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000002335 214.0
HKD2_k127_1381982_9 Belongs to the UPF0235 family K09131 - - 0.0000000000000002617 92.0
HKD2_k127_1387700_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 358.0
HKD2_k127_1387700_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001996 280.0
HKD2_k127_1387700_2 Protein of unknown function DUF99 K09120 - - 0.000000000000000000000000000000000000000000000000000000003804 226.0
HKD2_k127_1387700_3 Ami_2 - - - 0.00000000000000000000000000000000001155 154.0
HKD2_k127_1387700_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000417 150.0
HKD2_k127_1387700_5 - - - - 0.0000000000000000000000007538 115.0
HKD2_k127_1387700_6 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000001321 70.0
HKD2_k127_1391877_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000003699 237.0
HKD2_k127_1391877_1 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000001692 99.0
HKD2_k127_1392410_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000003194 265.0
HKD2_k127_1392410_1 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000003052 248.0
HKD2_k127_1392410_2 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000006052 234.0
HKD2_k127_1395004_0 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 586.0
HKD2_k127_1395004_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 402.0
HKD2_k127_1395004_2 Alpha-1,2-mannosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 378.0
HKD2_k127_1395004_3 - - - - 0.00001376 51.0
HKD2_k127_13965_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 4.091e-206 648.0
HKD2_k127_13965_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009521 315.0
HKD2_k127_13965_2 membrane organization K07126,K07277 - - 0.000000000000000000000000000003181 133.0
HKD2_k127_1400848_0 Aminotransferase class-V - - - 2.703e-228 717.0
HKD2_k127_1400848_1 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 291.0
HKD2_k127_1400848_2 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000447 228.0
HKD2_k127_1400848_3 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000003473 138.0
HKD2_k127_1402796_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001407 295.0
HKD2_k127_1402796_1 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000003405 250.0
HKD2_k127_1402796_2 DbpA RNA binding domain K03732,K05592 - 3.6.4.13 0.000000000000000000000000000000000000003897 149.0
HKD2_k127_1402796_3 Belongs to the GbsR family - - - 0.0000000000000000000000000000000000003555 151.0
HKD2_k127_1402796_4 ATP ADP translocase K03301 - - 0.00000000000004272 76.0
HKD2_k127_1409614_0 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 536.0
HKD2_k127_1409614_1 - - - - 0.000000000000000000000000000000000000000000008133 176.0
HKD2_k127_1409693_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 361.0
HKD2_k127_1409693_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 346.0
HKD2_k127_1425458_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 468.0
HKD2_k127_1425458_1 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 395.0
HKD2_k127_1425458_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000004781 213.0
HKD2_k127_1425458_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000001033 183.0
HKD2_k127_1425458_4 Transcriptional regulator K22106 - - 0.000000000000000000000000000000003977 135.0
HKD2_k127_1427321_0 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 304.0
HKD2_k127_1427321_1 Domains REC, HisKA, HATPase_c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006447 269.0
HKD2_k127_1427321_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000005293 113.0
HKD2_k127_1427321_3 cyclic nucleotide binding K00384,K01420 - 1.8.1.9 0.0000000000000000002647 102.0
HKD2_k127_1428040_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1229.0
HKD2_k127_1428040_1 Histidine kinase A domain protein - - - 0.00000000000000000000000001001 114.0
HKD2_k127_1428040_2 cellular manganese ion homeostasis - - - 0.0000000000000000003713 93.0
HKD2_k127_1428040_3 membrane - - - 0.00000000009948 65.0
HKD2_k127_1428040_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000003249 69.0
HKD2_k127_1428070_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000007041 164.0
HKD2_k127_1428070_2 Melibiase K07407 GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0009056,GO:0015925,GO:0016137,GO:0016139,GO:0016787,GO:0016798,GO:0042802,GO:0042803,GO:0046983,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 3.2.1.22 0.00000000000000000000000008148 118.0
HKD2_k127_1428070_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000002499 93.0
HKD2_k127_1428070_4 Component of the counting factor (CF) complex - GO:0005575,GO:0005576,GO:0006928,GO:0006950,GO:0007154,GO:0007155,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0022610,GO:0030587,GO:0031152,GO:0031667,GO:0031668,GO:0031669,GO:0032502,GO:0033500,GO:0033554,GO:0040011,GO:0042592,GO:0042593,GO:0042594,GO:0044764,GO:0048856,GO:0048870,GO:0048878,GO:0050896,GO:0051179,GO:0051674,GO:0051703,GO:0051704,GO:0051716,GO:0065007,GO:0065008,GO:0071496,GO:0090702,GO:0098609,GO:0098630,GO:0098743,GO:0099120 - 0.000000002008 71.0
HKD2_k127_1429069_0 DNA mismatch repair protein K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 523.0
HKD2_k127_1429069_2 Domain of unknown function (DUF4185) - - - 0.0006616 52.0
HKD2_k127_1430643_0 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000041 295.0
HKD2_k127_1430643_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000001927 148.0
HKD2_k127_1430643_2 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000003113 142.0
HKD2_k127_1433921_0 PrkA serine protein kinase C-terminal domain - - - 1.513e-290 910.0
HKD2_k127_1433921_1 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 410.0
HKD2_k127_1433921_2 TIGRFAM MATE efflux family protein K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 326.0
HKD2_k127_1433921_3 TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 306.0
HKD2_k127_1433921_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001439 242.0
HKD2_k127_1433921_6 Universal stress protein - - - 0.0000000002685 68.0
HKD2_k127_1433921_7 TonB C terminal K03832 - - 0.000001616 60.0
HKD2_k127_1433921_9 Protein of unknown function (DUF559) - - - 0.0004444 50.0
HKD2_k127_1441620_0 Polysaccharide biosynthesis protein K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 351.0
HKD2_k127_1441620_1 Hypothetical glycosyl hydrolase family 15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 310.0
HKD2_k127_1441983_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 336.0
HKD2_k127_1441983_1 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001042 261.0
HKD2_k127_1441983_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000005737 177.0
HKD2_k127_1441983_3 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000000000000000000000004854 157.0
HKD2_k127_1441983_4 Protein of unknown function (DUF3105) - - - 0.0000000000000000000000000000000000002638 149.0
HKD2_k127_1441983_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000003287 147.0
HKD2_k127_1442379_0 High confidence in function and specificity - - - 0.00000000000000000000000000000000008474 140.0
HKD2_k127_1442379_1 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000000000000000000000000000003323 151.0
HKD2_k127_1442379_2 - - - - 0.0000000000000000001906 104.0
HKD2_k127_1442379_3 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000008326 66.0
HKD2_k127_1444435_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0005102 43.0
HKD2_k127_1447330_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 351.0
HKD2_k127_1447330_1 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000000236 204.0
HKD2_k127_1447330_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.000000001393 69.0
HKD2_k127_1447330_4 - - - - 0.0006945 49.0
HKD2_k127_1454845_0 VWA domain containing CoxE-like protein K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 483.0
HKD2_k127_1454845_1 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000003567 181.0
HKD2_k127_1454845_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000111 154.0
HKD2_k127_1461131_0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 301.0
HKD2_k127_1461131_1 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 320.0
HKD2_k127_1461131_2 Uncharacterised conserved protein (DUF2156) K14205 - 2.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001469 276.0
HKD2_k127_1461131_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000001565 248.0
HKD2_k127_1461131_4 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000000000000000000000000001536 244.0
HKD2_k127_1461131_5 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000001658 215.0
HKD2_k127_146236_0 Steryl acetyl hydrolase K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006002 277.0
HKD2_k127_146236_1 lysozyme activity K07260 - 3.4.17.14 0.00000000000000000000000000000000000000000000000000000000008797 226.0
HKD2_k127_146236_2 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000006163 174.0
HKD2_k127_146236_3 50S ribosome-binding GTPase - - - 0.0000000000000000000000000000003764 127.0
HKD2_k127_146236_4 YhhN family - - - 0.0000000000000000000000000004646 122.0
HKD2_k127_1471969_0 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 346.0
HKD2_k127_1471969_1 SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000000000000003461 198.0
HKD2_k127_1471969_2 Integral membrane - - - 0.000000000000000000000001267 112.0
HKD2_k127_1471969_3 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.0000002911 56.0
HKD2_k127_1473729_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 4.526e-265 849.0
HKD2_k127_1473729_1 DNA-binding response regulator K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 540.0
HKD2_k127_1473729_2 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 460.0
HKD2_k127_1473729_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 366.0
HKD2_k127_1473729_4 HAMP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 328.0
HKD2_k127_1473729_5 MerR, DNA binding K19591 - - 0.0000000000000000000000000000000000000000000000002835 181.0
HKD2_k127_1473729_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000001359 177.0
HKD2_k127_1473729_7 Thioesterase K07107 - - 0.0000000000000000000000000000000000000000003008 177.0
HKD2_k127_1473729_8 cheY-homologous receiver domain - - - 0.0000000000000000000000003154 116.0
HKD2_k127_1474962_0 COG1061 DNA or RNA helicases of superfamily II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 301.0
HKD2_k127_1474962_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000001329 174.0
HKD2_k127_1474962_2 COGs COG3372 conserved K09744 - - 0.0000000000000000000000000000000000005097 155.0
HKD2_k127_1474962_3 Protein of unknown function (DUF1156) - - - 0.0000000000000000000002508 100.0
HKD2_k127_1490456_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 5.248e-271 883.0
HKD2_k127_1490456_1 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 335.0
HKD2_k127_1490456_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07663,K14981 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008869 279.0
HKD2_k127_1490456_3 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000004459 246.0
HKD2_k127_1490456_4 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000003336 242.0
HKD2_k127_1490456_5 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000002583 225.0
HKD2_k127_1490456_6 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000471 203.0
HKD2_k127_1490456_7 Cysteine-rich secretory protein family - - - 0.000000000000000002574 97.0
HKD2_k127_1490456_8 - - - - 0.0002323 49.0
HKD2_k127_1491727_0 Peptidase, M16 K07263 - - 0.000000000000000000000000000000008419 141.0
HKD2_k127_1491727_1 - - - - 0.0000000000000000000008003 100.0
HKD2_k127_1497119_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 332.0
HKD2_k127_1497119_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 314.0
HKD2_k127_1497119_2 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 334.0
HKD2_k127_1497119_4 DNA binding domain with preference for A/T rich regions K06223,K07318 - 2.1.1.72 0.000000000000000000000000000000000000000000000001399 178.0
HKD2_k127_1504964_0 PFAM sigma-54 factor interaction domain-containing protein K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 394.0
HKD2_k127_1504964_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001063 275.0
HKD2_k127_1504964_3 Cadherin-like beta sandwich domain - - - 0.0000002008 63.0
HKD2_k127_151042_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001098 280.0
HKD2_k127_151042_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000005105 224.0
HKD2_k127_151042_2 GAF domain - - - 0.000000000005418 66.0
HKD2_k127_1512432_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000002776 123.0
HKD2_k127_1512432_1 B12 binding domain K01849 - 5.4.99.2 0.000000000001477 80.0
HKD2_k127_1514475_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 519.0
HKD2_k127_1514475_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 465.0
HKD2_k127_1514475_2 Aminotransferase K00813,K00832 GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0008793,GO:0009058,GO:0009066,GO:0009067,GO:0009072,GO:0009073,GO:0009081,GO:0009082,GO:0009094,GO:0009095,GO:0009098,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019292,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050048,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.6.1.1,2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 407.0
HKD2_k127_1514475_3 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 310.0
HKD2_k127_1514475_4 - - - - 0.000000000000000000000000000000000000000000000000001658 206.0
HKD2_k127_1514475_5 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000008672 105.0
HKD2_k127_1514475_6 - - - - 0.00000002427 64.0
HKD2_k127_1515085_0 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 522.0
HKD2_k127_1515085_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 473.0
HKD2_k127_1515085_12 Beta-L-arabinofuranosidase, GH127 - - - 0.0004823 52.0
HKD2_k127_1515085_2 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 400.0
HKD2_k127_1515085_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 326.0
HKD2_k127_1515085_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 314.0
HKD2_k127_1515085_5 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 305.0
HKD2_k127_1515085_6 PFAM response regulator receiver K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004045 276.0
HKD2_k127_1515085_7 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000003529 257.0
HKD2_k127_1515085_8 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000003254 236.0
HKD2_k127_1515085_9 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000005522 203.0
HKD2_k127_1516038_0 COG1073 hydrolases of the alpha beta superfamily - - - 6.777e-198 660.0
HKD2_k127_1516038_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 521.0
HKD2_k127_1516038_2 COG2755 Lysophospholipase L1 and related esterases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 349.0
HKD2_k127_1516038_3 Long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001168 287.0
HKD2_k127_1516038_4 COG2755 Lysophospholipase L1 and related esterases - - - 0.00000000000000000000000000000000000000000000000000000000000005907 232.0
HKD2_k127_1516038_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000002045 216.0
HKD2_k127_1516038_6 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000004098 198.0
HKD2_k127_1516038_7 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000002324 207.0
HKD2_k127_1519780_0 benzoyl-CoA reductase K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 295.0
HKD2_k127_1519780_1 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000007389 244.0
HKD2_k127_1525368_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 456.0
HKD2_k127_1525368_1 glycoside hydrolase, family K07273 - - 0.000000000000000000000000000000000000000000000005762 192.0
HKD2_k127_1525368_2 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000002372 158.0
HKD2_k127_1525905_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 518.0
HKD2_k127_1525905_1 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000001495 232.0
HKD2_k127_1525905_2 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000003793 205.0
HKD2_k127_1525905_3 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000003297 194.0
HKD2_k127_1525905_4 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000001238 142.0
HKD2_k127_1531554_0 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 601.0
HKD2_k127_1531554_1 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 454.0
HKD2_k127_1531554_2 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 446.0
HKD2_k127_1531554_4 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005702 256.0
HKD2_k127_1531554_6 - - - - 0.000001295 59.0
HKD2_k127_1543461_0 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 428.0
HKD2_k127_1543461_1 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 347.0
HKD2_k127_1543461_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 354.0
HKD2_k127_1543461_3 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 356.0
HKD2_k127_1543461_4 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 352.0
HKD2_k127_1543461_6 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000009799 238.0
HKD2_k127_1543461_7 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000163 149.0
HKD2_k127_1543461_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000002559 148.0
HKD2_k127_1543505_0 PFAM 6-phosphogluconate dehydrogenase NAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 357.0
HKD2_k127_1543505_1 COG0451 Nucleoside-diphosphate-sugar epimerases K05281 - 1.3.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000004113 265.0
HKD2_k127_1543505_2 inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.00000000000000000000000000000009304 132.0
HKD2_k127_1551583_0 B12 binding domain - - - 0.00000000000000000000000000000000001156 147.0
HKD2_k127_1551583_1 Ammonium Transporter Family K03320 - - 0.00000000000006565 72.0
HKD2_k127_1551583_2 B12 binding domain - - - 0.00000002063 64.0
HKD2_k127_1551583_3 Furin-like repeats K01349,K08654 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0032879,GO:0043170,GO:0044238,GO:0044464,GO:0048519,GO:0050789,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.21.75 0.0004732 49.0
HKD2_k127_1551583_4 amine dehydrogenase activity - - - 0.0005894 52.0
HKD2_k127_1561598_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 4.784e-212 681.0
HKD2_k127_1561598_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 540.0
HKD2_k127_1561598_10 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000007436 201.0
HKD2_k127_1561598_11 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.00000000000000000000000000000000000000000002738 172.0
HKD2_k127_1561598_12 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000002241 146.0
HKD2_k127_1561598_13 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000001371 129.0
HKD2_k127_1561598_14 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.00000000000000000000000001935 113.0
HKD2_k127_1561598_15 glucose 6-phosphate dehydrogenase - - - 0.00000000000000000000004197 115.0
HKD2_k127_1561598_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 531.0
HKD2_k127_1561598_3 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 502.0
HKD2_k127_1561598_4 translation initiation factor activity K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 369.0
HKD2_k127_1561598_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 347.0
HKD2_k127_1561598_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 314.0
HKD2_k127_1561598_7 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002189 271.0
HKD2_k127_1561598_8 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000003194 245.0
HKD2_k127_1561598_9 fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000001177 228.0
HKD2_k127_1562324_0 pyridine nucleotide-disulfide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 569.0
HKD2_k127_1562324_1 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 544.0
HKD2_k127_1562324_10 - - - - 0.00000001231 68.0
HKD2_k127_1562324_11 serine-type aminopeptidase activity - - - 0.00002876 57.0
HKD2_k127_1562324_2 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 373.0
HKD2_k127_1562324_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 332.0
HKD2_k127_1562324_4 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000004611 212.0
HKD2_k127_1562324_5 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000002501 180.0
HKD2_k127_1562324_7 diguanylate cyclase K21020 - 2.7.7.65 0.0000000000000000000000000001185 130.0
HKD2_k127_1562324_8 Serine aminopeptidase, S33 - - - 0.000000000000000000000004324 106.0
HKD2_k127_1576626_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.829e-271 863.0
HKD2_k127_1576626_1 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000001479 185.0
HKD2_k127_1576626_2 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0001491 49.0
HKD2_k127_1579342_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008399 302.0
HKD2_k127_1579342_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000001694 179.0
HKD2_k127_1579342_2 Ferredoxin - - - 0.0000000000000001035 86.0
HKD2_k127_1579342_3 - - - - 0.00005156 53.0
HKD2_k127_1580700_0 Tetratricopeptide repeats - - - 3.729e-236 790.0
HKD2_k127_1580700_1 Type ii and iii secretion system protein - - - 0.0000000000000000000000000000003512 128.0
HKD2_k127_1584450_0 HAD-superfamily phosphatase subfamily IIIC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 478.0
HKD2_k127_1584450_1 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 442.0
HKD2_k127_1584450_10 - - - - 0.0000000000000009579 88.0
HKD2_k127_1584450_11 response regulator receiver - - - 0.000000000000001885 81.0
HKD2_k127_1584450_13 seryl-tRNA synthetase - - - 0.00000000001896 66.0
HKD2_k127_1584450_14 Maltose acetyltransferase K00661 - 2.3.1.79 0.00000000002379 74.0
HKD2_k127_1584450_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 390.0
HKD2_k127_1584450_3 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 397.0
HKD2_k127_1584450_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 352.0
HKD2_k127_1584450_5 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000006379 264.0
HKD2_k127_1584450_6 extracellular polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000178 233.0
HKD2_k127_1584450_7 Phosphopantetheine attachment site - - - 0.000000000000000000000000007517 114.0
HKD2_k127_1584450_8 PFAM Bacterial transferase hexapeptide (three repeats) - - - 0.00000000000000000001521 108.0
HKD2_k127_1584450_9 holo-[acyl-carrier-protein] synthase activity K00997 - 2.7.8.7 0.0000000000000000001022 94.0
HKD2_k127_1585825_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000001216 237.0
HKD2_k127_1585825_1 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000009852 233.0
HKD2_k127_1585825_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.00000000000000000000000000000006634 134.0
HKD2_k127_1585825_3 PKD domain containing protein K01179,K07004,K13277,K20276,K21449 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.2.1.4 0.00000001288 66.0
HKD2_k127_1585825_4 Involved in the tonB-independent uptake of proteins - - - 0.00004545 51.0
HKD2_k127_158960_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 454.0
HKD2_k127_158960_1 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 403.0
HKD2_k127_158960_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000003615 150.0
HKD2_k127_158960_3 acid phosphatase activity K03651 - 3.1.4.53 0.0000000000000000000000000000002331 137.0
HKD2_k127_158960_4 ABC transporter K06020 - 3.6.3.25 0.00000000000000000005793 91.0
HKD2_k127_1596654_0 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 340.0
HKD2_k127_1596654_1 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009584 293.0
HKD2_k127_1596654_2 POT family K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006869 243.0
HKD2_k127_1596654_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000008215 154.0
HKD2_k127_1600686_0 Glycosyl hydrolase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 582.0
HKD2_k127_1600686_1 Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 511.0
HKD2_k127_1600686_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000001267 188.0
HKD2_k127_1600686_11 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.000000000000000000000000000000000000000000000001549 183.0
HKD2_k127_1600686_12 lyase activity - - - 0.00000000000000000000000000000000000000000001845 174.0
HKD2_k127_1600686_13 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000008664 170.0
HKD2_k127_1600686_14 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000001659 171.0
HKD2_k127_1600686_15 Acyl-ACP thioesterase K07107 - - 0.000000000000000000000000000000000001081 143.0
HKD2_k127_1600686_16 palmitoyl-(protein) hydrolase activity - - - 0.00000000000003301 83.0
HKD2_k127_1600686_17 serine threonine protein kinase - - - 0.0000000000000616 85.0
HKD2_k127_1600686_2 beta-glucosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 488.0
HKD2_k127_1600686_20 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.000000005027 61.0
HKD2_k127_1600686_21 Chlorophyllase-2 K08099 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006787,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009507,GO:0009536,GO:0009987,GO:0015994,GO:0015996,GO:0016787,GO:0016788,GO:0019439,GO:0033013,GO:0033015,GO:0034641,GO:0042440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046149,GO:0046483,GO:0046700,GO:0047746,GO:0051186,GO:0051187,GO:0052689,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.1.1.14 0.000002541 59.0
HKD2_k127_1600686_22 - - - - 0.000176 44.0
HKD2_k127_1600686_3 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 415.0
HKD2_k127_1600686_4 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 399.0
HKD2_k127_1600686_5 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 352.0
HKD2_k127_1600686_7 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 330.0
HKD2_k127_1600686_8 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000002984 203.0
HKD2_k127_1600686_9 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000001717 195.0
HKD2_k127_1616355_0 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000112 134.0
HKD2_k127_1616355_1 HD domain - - - 0.000007411 49.0
HKD2_k127_1621604_0 oxidoreductase activity K11153 - 1.1.1.300 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 308.0
HKD2_k127_1621604_1 PFAM glutaredoxin - - - 0.0000000000000000000000000000000000009883 147.0
HKD2_k127_1621604_2 NAD(P)H-binding - - - 0.0000000000000000000000000000000002152 147.0
HKD2_k127_1621604_3 - - - - 0.000000000000000000000000000008441 137.0
HKD2_k127_1621604_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000003598 89.0
HKD2_k127_1621604_7 spectrin binding - - - 0.000000003098 70.0
HKD2_k127_1621604_9 - - - - 0.0009916 48.0
HKD2_k127_1631062_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 314.0
HKD2_k127_1631062_1 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005466 280.0
HKD2_k127_1631062_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000003634 215.0
HKD2_k127_1631062_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000001047 195.0
HKD2_k127_1631062_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000001716 155.0
HKD2_k127_1631062_5 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00002766 52.0
HKD2_k127_1634957_0 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 497.0
HKD2_k127_1634957_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 446.0
HKD2_k127_1634957_2 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001347 290.0
HKD2_k127_1634957_3 NnrS protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003915 269.0
HKD2_k127_1634957_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K07052 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000002505 237.0
HKD2_k127_1634957_5 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000988 135.0
HKD2_k127_1634957_6 DoxX-like family - - - 0.000000000000000000000000001658 116.0
HKD2_k127_1634957_8 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00001111 56.0
HKD2_k127_1636004_0 Family membership - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 616.0
HKD2_k127_1636004_1 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001478 300.0
HKD2_k127_1636004_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005806 282.0
HKD2_k127_1636004_3 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000001234 214.0
HKD2_k127_1636004_4 PAS fold K02482 - 2.7.13.3 0.00000000000000000000006459 113.0
HKD2_k127_1636004_5 - - - - 0.000000000000001597 89.0
HKD2_k127_1636004_6 peptidyl-tyrosine sulfation - - - 0.00001471 57.0
HKD2_k127_1641420_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 420.0
HKD2_k127_1641420_1 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 312.0
HKD2_k127_1641420_2 cell envelope organization K05807,K08309 - - 0.00000000000000000000000000000000000000000000000001336 192.0
HKD2_k127_1641420_3 periplasmic or secreted lipoprotein - - - 0.0000000000000005093 84.0
HKD2_k127_1643608_0 RNA-DNA hybrid ribonuclease activity K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 301.0
HKD2_k127_1643608_1 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006695 293.0
HKD2_k127_1643608_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000000000000000000000000001066 209.0
HKD2_k127_1643608_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000001542 172.0
HKD2_k127_1643608_5 pilus assembly protein PilW K02672 - - 0.000000000000000000000000001756 129.0
HKD2_k127_1643608_6 type IV pilus modification protein PilV K02671,K02681 - - 0.000000000000002901 89.0
HKD2_k127_1643608_8 Pfam:N_methyl_2 K02456,K02650 - - 0.000629 51.0
HKD2_k127_1648808_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 364.0
HKD2_k127_1648808_1 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000001216 149.0
HKD2_k127_1649378_0 aconitate hydratase K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 534.0
HKD2_k127_1649378_1 - K07283 - - 0.0000000000000000000000000000000000000000000001207 179.0
HKD2_k127_166119_0 phosphoesterases, related to the Icc protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 318.0
HKD2_k127_166119_1 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 312.0
HKD2_k127_166119_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000002438 230.0
HKD2_k127_166119_3 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000002171 168.0
HKD2_k127_166119_4 cell envelope organization K05807,K08309 - - 0.0000000000000000000000000000000000000000002886 174.0
HKD2_k127_166119_5 PFAM UBA THIF-type NAD FAD binding - - - 0.0000000000000000001395 100.0
HKD2_k127_166119_6 Endonuclease/Exonuclease/phosphatase family K12603,K20363 GO:0000003,GO:0000075,GO:0000077,GO:0000175,GO:0000278,GO:0000288,GO:0000289,GO:0000291,GO:0000956,GO:0003006,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004535,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006977,GO:0007049,GO:0007093,GO:0007154,GO:0007165,GO:0007276,GO:0007281,GO:0007292,GO:0007346,GO:0008150,GO:0008152,GO:0008284,GO:0008356,GO:0008408,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010564,GO:0010603,GO:0010604,GO:0010605,GO:0010606,GO:0010608,GO:0010629,GO:0010638,GO:0010948,GO:0016070,GO:0016071,GO:0016441,GO:0016458,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017145,GO:0017148,GO:0019219,GO:0019222,GO:0019439,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0023052,GO:0030014,GO:0030154,GO:0030330,GO:0031047,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031331,GO:0031334,GO:0031570,GO:0031571,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033043,GO:0033554,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0035194,GO:0035195,GO:0035556,GO:0040029,GO:0042078,GO:0042127,GO:0042770,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0043487,GO:0043488,GO:0043928,GO:0044087,GO:0044089,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044773,GO:0044774,GO:0044783,GO:0044819,GO:0045786,GO:0045787,GO:0045930,GO:0045935,GO:0046483,GO:0046700,GO:0048132,GO:0048468,GO:0048477,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048609,GO:0048856,GO:0048869,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051301,GO:0051704,GO:0051716,GO:0051726,GO:0060255,GO:0061013,GO:0061014,GO:0061157,GO:0065007,GO:0065008,GO:0065009,GO:0070966,GO:0071156,GO:0071158,GO:0071704,GO:0072331,GO:0072395,GO:0072401,GO:0072413,GO:0072422,GO:0072431,GO:0080090,GO:0090068,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0098722,GO:0098728,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902115,GO:1902117,GO:1902400,GO:1902402,GO:1902403,GO:1902680,GO:1902806,GO:1902807,GO:1903047,GO:1903311,GO:1903313,GO:1903506,GO:1903508,GO:2000045,GO:2000112,GO:2000113,GO:2000134,GO:2000325,GO:2000327,GO:2001141 3.1.13.4 0.000000005107 66.0
HKD2_k127_1665761_0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K03624,K04760 - - 0.000000000000000000000000000000000007869 141.0
HKD2_k127_1665761_1 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000002881 144.0
HKD2_k127_1665761_2 Alpha beta hydrolase K01563 - 3.8.1.5 0.0000000000000000000002562 97.0
HKD2_k127_1667167_0 WD40-like Beta Propeller Repeat - - - 0.0 1118.0
HKD2_k127_1667167_1 Protein conserved in bacteria K09800 - - 1.577e-212 706.0
HKD2_k127_1667167_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 593.0
HKD2_k127_1667167_3 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 342.0
HKD2_k127_1667167_4 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 301.0
HKD2_k127_1667167_5 Protein of unknown function (DUF1318) - - - 0.0000000000000000000000000000000000000000000000000006523 212.0
HKD2_k127_1671990_0 Acyl-CoA dehydrogenase, C-terminal domain K00249,K11731 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 528.0
HKD2_k127_1671990_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 468.0
HKD2_k127_1671990_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 356.0
HKD2_k127_1671990_3 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.00000000000000000000000000000000000000007506 167.0
HKD2_k127_1671990_4 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000002639 158.0
HKD2_k127_1671990_5 - - - - 0.000000000000000000000000000000004411 147.0
HKD2_k127_1671990_6 Membrane bound O-acyl transferase family - - - 0.00000000000000000000000000000002747 145.0
HKD2_k127_1671990_7 - - - - 0.00003862 53.0
HKD2_k127_1672263_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.872e-253 808.0
HKD2_k127_1672263_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 389.0
HKD2_k127_1672263_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000002127 224.0
HKD2_k127_1672263_3 Cysteine-rich motif following a subset of SET domains K07117 - - 0.000000001947 70.0
HKD2_k127_1672263_4 - - - - 0.0000002775 53.0
HKD2_k127_1674446_1 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 368.0
HKD2_k127_1674446_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 318.0
HKD2_k127_1674446_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 304.0
HKD2_k127_1674446_4 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000003233 243.0
HKD2_k127_1674446_5 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000002052 237.0
HKD2_k127_1674446_7 Protein of unknown function (DUF507) K09804 - - 0.0000000000000000000000000000000000000000000554 166.0
HKD2_k127_1675035_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 567.0
HKD2_k127_1675035_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 527.0
HKD2_k127_1675035_10 Archease protein family (MTH1598/TM1083) - - - 0.00002409 54.0
HKD2_k127_1675035_2 Dienelactone hydrolase family K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 466.0
HKD2_k127_1675035_3 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004119 271.0
HKD2_k127_1675035_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000004535 186.0
HKD2_k127_1675035_5 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000004987 186.0
HKD2_k127_1675035_6 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000006234 126.0
HKD2_k127_1675035_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000006657 99.0
HKD2_k127_1675035_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000192 88.0
HKD2_k127_1680574_0 Belongs to the glycosyl hydrolase 2 family - - - 7.442e-262 839.0
HKD2_k127_1680574_1 UDP-galactopyranose mutase K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 622.0
HKD2_k127_1680574_10 - - - - 0.000000000000000000000000000000000000000000000001058 186.0
HKD2_k127_1680574_11 domain protein - - - 0.00000000000000000000000000001937 132.0
HKD2_k127_1680574_12 - - - - 0.00000000000000000000000001007 120.0
HKD2_k127_1680574_13 - - - - 0.00000000000000000000000001396 123.0
HKD2_k127_1680574_14 ASPIC and UnbV - - - 0.000000000000000000000002323 119.0
HKD2_k127_1680574_15 PFAM CHAD domain containing protein - - - 0.0000000000001308 82.0
HKD2_k127_1680574_16 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000007491 64.0
HKD2_k127_1680574_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 552.0
HKD2_k127_1680574_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008694 464.0
HKD2_k127_1680574_4 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 441.0
HKD2_k127_1680574_5 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 393.0
HKD2_k127_1680574_6 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 372.0
HKD2_k127_1680574_7 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 303.0
HKD2_k127_1680574_8 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001563 255.0
HKD2_k127_1680574_9 Phosphoesterase family K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000009489 193.0
HKD2_k127_1689827_0 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 3.081e-257 808.0
HKD2_k127_1689827_1 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.000000000000000000000000000000000000001115 166.0
HKD2_k127_1689827_2 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000000008349 151.0
HKD2_k127_169442_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.058e-196 629.0
HKD2_k127_169442_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 412.0
HKD2_k127_169442_10 cellulose binding - - - 0.0000000000000004056 93.0
HKD2_k127_169442_11 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000008413 81.0
HKD2_k127_169442_12 Peptidase family M23 - - - 0.0000000000007194 79.0
HKD2_k127_169442_15 cellulase activity - - - 0.000000006146 66.0
HKD2_k127_169442_16 Heavy-metal resistance - - - 0.00000001519 64.0
HKD2_k127_169442_17 KR domain K00019 - 1.1.1.30 0.00000005062 56.0
HKD2_k127_169442_18 CAAX protease self-immunity K07052 - - 0.0000003317 61.0
HKD2_k127_169442_19 Chitinase class I K03791 - - 0.0000008214 53.0
HKD2_k127_169442_2 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 344.0
HKD2_k127_169442_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 295.0
HKD2_k127_169442_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000004066 239.0
HKD2_k127_169442_5 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000001088 167.0
HKD2_k127_169442_6 RNA recognition motif - - - 0.000000000000000000000001077 107.0
HKD2_k127_169442_7 Polysaccharide lyase - - - 0.000000000000000000000008641 117.0
HKD2_k127_169442_8 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000001758 107.0
HKD2_k127_169442_9 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K00648 - 2.3.1.180 0.00000000000000008815 95.0
HKD2_k127_1695474_0 Tetratricopeptide repeat - - - 1.035e-209 691.0
HKD2_k127_1695474_1 GTP-binding protein K06207 - - 0.00000000000000000000000000002271 118.0
HKD2_k127_1721886_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 400.0
HKD2_k127_1721886_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 379.0
HKD2_k127_1721886_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 297.0
HKD2_k127_1721886_3 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000008436 250.0
HKD2_k127_1721886_4 - - - - 0.0000000000000000000000000000000000000000000000000000000006262 209.0
HKD2_k127_1721886_5 DMT(Drug metabolite transporter) superfamily permease - - - 0.00000000000000000000000000000000000000000000000000001148 201.0
HKD2_k127_1721886_6 protein deglycation K03152,K05520,K12132 - 2.7.11.1,3.5.1.124 0.0000000000000000000000000000000000005639 146.0
HKD2_k127_1721886_8 - - - - 0.000000000000009848 87.0
HKD2_k127_1721886_9 Gluconate 2-dehydrogenase K06152 - 1.1.99.3 0.000004451 57.0
HKD2_k127_1723701_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000006819 211.0
HKD2_k127_1723701_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000001452 150.0
HKD2_k127_1723701_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000001433 129.0
HKD2_k127_1723701_3 nitric oxide dioxygenase activity K17247 - - 0.000000000000000000000002444 112.0
HKD2_k127_1723701_4 - - - - 0.0000005005 59.0
HKD2_k127_1729262_0 transferase activity, transferring glycosyl groups K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000003531 235.0
HKD2_k127_1729262_1 Glycosyltransferase Family 4 K14335 - - 0.00000000000000000000000000000000000000000000000000000000000000006484 239.0
HKD2_k127_1729262_2 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.000000000000000000000000000001414 129.0
HKD2_k127_173215_0 response regulator K07714 - - 4.426e-224 701.0
HKD2_k127_173215_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase K00322 - 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 475.0
HKD2_k127_173215_2 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 446.0
HKD2_k127_173215_3 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000002951 259.0
HKD2_k127_173215_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000112 167.0
HKD2_k127_173215_5 Transglycosylase associated protein - - - 0.00000000000000000000000000000000002056 138.0
HKD2_k127_173215_6 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000007049 49.0
HKD2_k127_174420_0 Signal transduction histidine kinase - - - 6.65e-209 671.0
HKD2_k127_174420_1 alcohol dehydrogenase K18012 - 1.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 408.0
HKD2_k127_174420_2 FHA domain - - - 0.000000000000000000000000000000000000003237 161.0
HKD2_k127_1746660_0 ABC transporter transmembrane region K06147,K18890 - - 6.227e-209 667.0
HKD2_k127_1746660_1 ABC transporter K06147,K18889 - - 1.602e-207 670.0
HKD2_k127_1746660_11 PilZ domain K02676 - - 0.0000000000000000000000000000000000003242 143.0
HKD2_k127_1746660_12 - - - - 0.000000000000000000000000000001623 129.0
HKD2_k127_1746660_13 Domain of unknown function (DUF5071) - - - 0.000000000000000000001301 101.0
HKD2_k127_1746660_14 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000008379 106.0
HKD2_k127_1746660_15 stigma-specific Stig1 family protein - GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0005575,GO:0005576,GO:0005615,GO:0006950,GO:0006952,GO:0006979,GO:0007154,GO:0007165,GO:0007275,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009725,GO:0009751,GO:0009753,GO:0009755,GO:0009791,GO:0009863,GO:0009867,GO:0009889,GO:0009987,GO:0010033,GO:0010035,GO:0010154,GO:0010193,GO:0010337,GO:0010565,GO:0010817,GO:0010941,GO:0010942,GO:0014070,GO:0019216,GO:0019217,GO:0019222,GO:0022414,GO:0023052,GO:0031323,GO:0031326,GO:0032350,GO:0032501,GO:0032502,GO:0032870,GO:0035690,GO:0042221,GO:0042304,GO:0042493,GO:0042742,GO:0043207,GO:0044421,GO:0046677,GO:0046885,GO:0046890,GO:0048316,GO:0048518,GO:0048522,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0061458,GO:0062012,GO:0065007,GO:0065008,GO:0070887,GO:0071229,GO:0071236,GO:0071310,GO:0071395,GO:0071407,GO:0071446,GO:0071495,GO:0080090,GO:0080140,GO:0080141,GO:0080142,GO:0098542,GO:1901700,GO:1901701 - 0.000000000000001664 88.0
HKD2_k127_1746660_18 Transcriptional regulator - - - 0.0001 52.0
HKD2_k127_1746660_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 485.0
HKD2_k127_1746660_3 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 497.0
HKD2_k127_1746660_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 433.0
HKD2_k127_1746660_5 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 312.0
HKD2_k127_1746660_6 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006281 274.0
HKD2_k127_1746660_7 PFAM Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004135 254.0
HKD2_k127_1746660_8 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000004582 267.0
HKD2_k127_1746660_9 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000004345 183.0
HKD2_k127_1752184_0 peptidyl-tyrosine sulfation - - - 6.853e-195 632.0
HKD2_k127_1752184_1 short-chain dehydrogenase K13774 - - 0.000000000000000000000000000000000007505 138.0
HKD2_k127_1752184_2 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000244 70.0
HKD2_k127_1773818_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 523.0
HKD2_k127_1773818_1 DsrC like protein K11179 - - 0.00000000000000001816 97.0
HKD2_k127_1773818_2 DsrE/DsrF/DrsH-like family - - - 0.000001612 50.0
HKD2_k127_1780226_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 533.0
HKD2_k127_1780226_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 458.0
HKD2_k127_1780226_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005601 276.0
HKD2_k127_1780226_3 - - - - 0.00000000000000000000000000000000000000000000000000000000001606 212.0
HKD2_k127_1780226_4 cell envelope organization K05807,K08309 - - 0.00000000000000000000000000000000000000087 167.0
HKD2_k127_1780226_5 Transcriptional regulatory protein, C terminal K07669,K07672 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000002464 83.0
HKD2_k127_1780226_6 extracellular matrix structural constituent - - - 0.000001073 62.0
HKD2_k127_1780226_7 - - - - 0.00002369 57.0
HKD2_k127_178442_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002027 264.0
HKD2_k127_178442_1 SpoVR like protein K06415 - - 0.000000000000000000000000000000000000001433 149.0
HKD2_k127_178442_2 Cold shock protein K03704 - - 0.000000000000000000000000000000008896 128.0
HKD2_k127_178442_3 - - - - 0.000000000000000007649 89.0
HKD2_k127_178442_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.000001145 51.0
HKD2_k127_1786676_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 584.0
HKD2_k127_1786676_1 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 426.0
HKD2_k127_1786676_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 355.0
HKD2_k127_1786676_3 Dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 317.0
HKD2_k127_1786676_4 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000004451 239.0
HKD2_k127_1786676_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000006189 66.0
HKD2_k127_179313_0 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 483.0
HKD2_k127_179313_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000527 194.0
HKD2_k127_179313_2 RNA-binding protein homologous to eukaryotic snRNP - - - 0.00000000000000000000000000000000000000000000008992 186.0
HKD2_k127_179313_4 abc transporter atp-binding protein K06861 - - 0.00000000000000000000000000000000000000000003253 175.0
HKD2_k127_179313_5 recA bacterial DNA recombination protein - - - 0.0000000000000000000000001363 113.0
HKD2_k127_179313_6 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000003615 118.0
HKD2_k127_179313_8 Protein conserved in bacteria K09774 - - 0.0000000001925 71.0
HKD2_k127_182350_0 Lamin Tail Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 614.0
HKD2_k127_182350_1 response to heat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003111 264.0
HKD2_k127_182350_2 PFAM O-methyltransferase family 2 K09846 - 2.1.1.210 0.00000000000000000000000000000000000000000007278 165.0
HKD2_k127_1834476_0 TonB dependent receptor K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 386.0
HKD2_k127_1834476_1 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 328.0
HKD2_k127_1834476_2 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001325 257.0
HKD2_k127_1834476_3 peptidyl-tyrosine sulfation - - - 0.000007932 53.0
HKD2_k127_1834476_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21564 - - 0.00002718 55.0
HKD2_k127_1837318_0 response regulator K02481,K07713 - - 4.899e-212 669.0
HKD2_k127_1837318_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000005853 217.0
HKD2_k127_1837318_2 COG3911 Predicted ATPase - - - 0.000000000000000000000000000000000000000000000000000000001633 205.0
HKD2_k127_1837318_3 Protoglobin - - - 0.000000000000000006493 83.0
HKD2_k127_1837318_4 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000008567 58.0
HKD2_k127_1839946_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 372.0
HKD2_k127_1839946_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000008573 233.0
HKD2_k127_1855909_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000001307 249.0
HKD2_k127_1855909_1 Alpha/beta hydrolase family K18053 - 1.13.12.5 0.000000000000000000000000000000000000000000000000000000000003315 220.0
HKD2_k127_1855909_2 HxlR-like helix-turn-helix - - - 0.00000000000000000000000002377 111.0
HKD2_k127_186418_0 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 605.0
HKD2_k127_186418_1 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 584.0
HKD2_k127_186418_2 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 444.0
HKD2_k127_186418_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 417.0
HKD2_k127_186418_5 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00005511 53.0
HKD2_k127_1866690_0 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 309.0
HKD2_k127_1866690_1 PFAM UvrB UvrC protein K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000006043 258.0
HKD2_k127_1872584_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 622.0
HKD2_k127_1872584_1 protein conserved in bacteria K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 337.0
HKD2_k127_1872584_10 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000004205 207.0
HKD2_k127_1872584_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000001229 209.0
HKD2_k127_1872584_12 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000004549 197.0
HKD2_k127_1872584_13 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000004866 182.0
HKD2_k127_1872584_14 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000005759 179.0
HKD2_k127_1872584_15 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000005672 142.0
HKD2_k127_1872584_16 protein trimerization - - - 0.0000000000000000000000000000000002511 148.0
HKD2_k127_1872584_17 - - - - 0.0000000000000000000000000227 121.0
HKD2_k127_1872584_18 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000002512 122.0
HKD2_k127_1872584_19 Oxidoreductase NAD-binding domain - - - 0.000000000000000074 90.0
HKD2_k127_1872584_2 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 296.0
HKD2_k127_1872584_21 protein kinase activity - - - 0.0000000001092 73.0
HKD2_k127_1872584_22 NosL - - - 0.00000003897 64.0
HKD2_k127_1872584_24 Sugar-specific transcriptional regulator TrmB - - - 0.00002176 55.0
HKD2_k127_1872584_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 283.0
HKD2_k127_1872584_4 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001904 278.0
HKD2_k127_1872584_5 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001427 271.0
HKD2_k127_1872584_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009428 255.0
HKD2_k127_1872584_7 Transcriptional regulator, CarD family K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002894 246.0
HKD2_k127_1872584_8 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002335 265.0
HKD2_k127_1872584_9 PFAM OmpA MotB domain protein K02557 - - 0.000000000000000000000000000000000000000000000000000000000000002063 228.0
HKD2_k127_1900211_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 355.0
HKD2_k127_1900211_1 FHA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 287.0
HKD2_k127_1900211_10 DnaJ molecular chaperone homology domain - - - 0.0000003665 63.0
HKD2_k127_1900211_11 Domain of unknown function (DUF4388) - - - 0.000001472 61.0
HKD2_k127_1900211_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000003015 222.0
HKD2_k127_1900211_5 Belongs to the ompA family K03640 - - 0.0000000000000000000003532 109.0
HKD2_k127_1900211_7 Belongs to the ompA family K03640 - - 0.0000000000000000004655 100.0
HKD2_k127_1900211_8 - - - - 0.000000003506 68.0
HKD2_k127_1900211_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000761 63.0
HKD2_k127_1900730_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 8.419e-213 677.0
HKD2_k127_1900730_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 388.0
HKD2_k127_1900730_2 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 314.0
HKD2_k127_1900730_3 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000452 157.0
HKD2_k127_1900730_4 YmaF family - - - 0.00000000000000000000000000007075 120.0
HKD2_k127_1900730_5 Putative MetA-pathway of phenol degradation - - - 0.00002525 55.0
HKD2_k127_1928561_0 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 517.0
HKD2_k127_1928561_1 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 421.0
HKD2_k127_1928561_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 385.0
HKD2_k127_1928561_3 to ATP-binding component of ABC transporters K10038 - - 0.00000000000000000000000000000000000000000000000000000000001335 214.0
HKD2_k127_1928561_4 AAA domain - - - 0.00000000000000000000000000000000000001388 164.0
HKD2_k127_1928561_5 peptidyl-prolyl cis-trans isomerase activity K03769,K03770,K07533 - 5.2.1.8 0.00027 48.0
HKD2_k127_1936400_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 364.0
HKD2_k127_1936400_1 FlhB HrpN YscU SpaS Family K02401 - - 0.00000000000000000000000000000000000000000115 178.0
HKD2_k127_1936400_2 Phage shock protein A K03969 - - 0.00000000000000000000000000000000002068 139.0
HKD2_k127_1936400_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000003506 136.0
HKD2_k127_1936400_5 cellulose binding - - - 0.000000000000005072 87.0
HKD2_k127_1941979_0 Tetratricopeptide repeat - - - 0.0 1052.0
HKD2_k127_1941979_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 284.0
HKD2_k127_1941979_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000003721 192.0
HKD2_k127_1941979_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000007072 132.0
HKD2_k127_1946543_0 Belongs to the ABC transporter superfamily K02031,K12371,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 407.0
HKD2_k127_1946543_1 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 410.0
HKD2_k127_1946543_2 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 402.0
HKD2_k127_1946543_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001798 272.0
HKD2_k127_1946543_4 Pfam matches to PF08238.7 Sel1, and to PF08238.7 Sel1, and to PF08238.7 Sel1, and to PF08238.7 Sel1 K07126 - - 0.000000000000000000000000000000000000000001383 177.0
HKD2_k127_1946543_5 Has antibacterial activity - GO:0000270,GO:0003674,GO:0003796,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0006897,GO:0006909,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0009605,GO:0009607,GO:0009617,GO:0016192,GO:0016787,GO:0016798,GO:0030203,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0042742,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0050830,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0061783,GO:0071704,GO:0097708,GO:0098542,GO:0098657,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000001886 89.0
HKD2_k127_1946829_0 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 443.0
HKD2_k127_1946829_2 metalloendopeptidase activity - - - 0.00000000000000000000000009531 124.0
HKD2_k127_1946829_3 nucleotide metabolic process - - - 0.000000000000000000002035 94.0
HKD2_k127_1951279_0 Putative glucoamylase K13688 - - 0.0 2315.0
HKD2_k127_1951279_1 PFAM DNA primase small subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 548.0
HKD2_k127_1951279_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 417.0
HKD2_k127_1951279_3 PFAM Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 323.0
HKD2_k127_1951279_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000003847 207.0
HKD2_k127_1951279_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000007551 160.0
HKD2_k127_1951279_7 Domain of unknown function (DUF3854) - - - 0.0004584 47.0
HKD2_k127_1951279_8 Dienelactone hydrolase family - - - 0.0009819 49.0
HKD2_k127_200066_0 DbpA RNA binding domain K03732,K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 310.0
HKD2_k127_200066_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000003555 176.0
HKD2_k127_200730_0 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 417.0
HKD2_k127_200730_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 360.0
HKD2_k127_200730_10 tetratricopeptide repeat - - - 0.000000000000005812 89.0
HKD2_k127_200730_11 Belongs to the UPF0109 family K06960 - - 0.0000000000008019 68.0
HKD2_k127_200730_12 Tetratricopeptide repeat - - - 0.000000007812 67.0
HKD2_k127_200730_13 Beta-L-arabinofuranosidase, GH127 - - - 0.00000009232 64.0
HKD2_k127_200730_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 321.0
HKD2_k127_200730_3 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 307.0
HKD2_k127_200730_4 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000003047 248.0
HKD2_k127_200730_5 SAM-dependent RNA methyltransferase - - - 0.0000000000000000000000000000000000000000000000001925 192.0
HKD2_k127_200730_6 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000006296 170.0
HKD2_k127_200730_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000156 162.0
HKD2_k127_200730_8 WHG domain - - - 0.0000000000000000000000000000002769 131.0
HKD2_k127_200730_9 PFAM methyltransferase small K15460 - 2.1.1.223 0.00000000000000000000000001289 118.0
HKD2_k127_20182_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 611.0
HKD2_k127_20182_1 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.000000000000000000002015 98.0
HKD2_k127_2059888_0 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 392.0
HKD2_k127_2059888_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001397 244.0
HKD2_k127_2059888_2 NUDIX hydrolase - - - 0.000000000000001787 83.0
HKD2_k127_2062305_0 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 293.0
HKD2_k127_2062305_2 - - - - 0.000000000000000000000000000000121 143.0
HKD2_k127_2062305_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000004944 134.0
HKD2_k127_2062305_6 SMART Elongator protein 3 MiaB NifB - - - 0.0002463 52.0
HKD2_k127_206749_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 505.0
HKD2_k127_206749_1 4Fe-4S single cluster domain K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 494.0
HKD2_k127_206749_10 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000001415 144.0
HKD2_k127_206749_11 Sodium Bile acid symporter family - - - 0.000000000000000000002766 107.0
HKD2_k127_206749_12 aminopeptidase N - - - 0.000000000000003447 89.0
HKD2_k127_206749_13 cell redox homeostasis K03671,K03672 - 1.8.1.8 0.00000000000002835 79.0
HKD2_k127_206749_14 Putative phosphatase (DUF442) - - - 0.0000000000006513 76.0
HKD2_k127_206749_2 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 500.0
HKD2_k127_206749_3 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 402.0
HKD2_k127_206749_4 PFAM Glutamine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 288.0
HKD2_k127_206749_5 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003416 269.0
HKD2_k127_206749_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000002788 249.0
HKD2_k127_206749_7 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000005198 235.0
HKD2_k127_206749_8 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000005179 230.0
HKD2_k127_206749_9 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000003953 202.0
HKD2_k127_207578_0 Protoglobin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 501.0
HKD2_k127_207578_1 Response regulator, receiver K03413 - - 0.00000000000000000000000000000000003014 139.0
HKD2_k127_207578_2 AMP binding - - - 0.0000000000000000000000000000000001359 138.0
HKD2_k127_2076278_0 Bacterial regulatory protein, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 424.0
HKD2_k127_2076278_1 Histidine kinase K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000007118 270.0
HKD2_k127_2076278_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000001674 100.0
HKD2_k127_2076278_3 Phage integrase family - - - 0.0000004286 57.0
HKD2_k127_208909_0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 445.0
HKD2_k127_208909_1 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000004682 108.0
HKD2_k127_208909_2 Vault protein inter-alpha-trypsin domain - - - 0.0000000000006173 79.0
HKD2_k127_2099468_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000002543 265.0
HKD2_k127_2099468_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000009005 199.0
HKD2_k127_2101540_0 TIGRFAM methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 2.202e-279 863.0
HKD2_k127_2101540_1 Amidohydrolase family K01464 - 3.5.2.2 8.437e-264 825.0
HKD2_k127_2101540_10 lactoylglutathione lyase activity - - - 0.00000008862 59.0
HKD2_k127_2101540_2 Carbon-nitrogen hydrolase K01431,K12251 - 3.5.1.53,3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 280.0
HKD2_k127_2101540_3 PFAM O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001062 238.0
HKD2_k127_2101540_5 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000802 148.0
HKD2_k127_2101540_6 signal peptide processing K03100 - 3.4.21.89 0.00000000000000000000000000000000002075 144.0
HKD2_k127_2101540_7 Glutaredoxin - - - 0.0000000000000000000000000006068 120.0
HKD2_k127_2101540_8 Belongs to the serpin family K13963 - - 0.000000000000000000000000001827 121.0
HKD2_k127_2101540_9 oxidoreductase activity K07114 - - 0.0000000006952 70.0
HKD2_k127_2107132_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 2.767e-251 817.0
HKD2_k127_2107132_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 511.0
HKD2_k127_2107132_10 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002643 265.0
HKD2_k127_2107132_11 synthase homocitrate synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000531 257.0
HKD2_k127_2107132_12 cellulose binding K13735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003198 268.0
HKD2_k127_2107132_13 PFAM Short-chain dehydrogenase reductase SDR K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000001074 252.0
HKD2_k127_2107132_14 Domain of unknown function (DUF4132) - - - 0.00000000000000000000000000000000000000000000000000000009384 224.0
HKD2_k127_2107132_16 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000001127 185.0
HKD2_k127_2107132_17 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000001316 169.0
HKD2_k127_2107132_18 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07538 - 1.1.1.368 0.00000000000000000000000000000000000000001185 164.0
HKD2_k127_2107132_19 LGFP repeat - - - 0.0000000000000000000000000000000000000003703 166.0
HKD2_k127_2107132_2 Major royal jelly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 463.0
HKD2_k127_2107132_20 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000013 142.0
HKD2_k127_2107132_21 nUDIX hydrolase - - - 0.0000000000000000000002321 102.0
HKD2_k127_2107132_22 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000002927 98.0
HKD2_k127_2107132_23 - - - - 0.00000000000001084 84.0
HKD2_k127_2107132_24 Phosphonate ABC K02044 - - 0.00000000004081 74.0
HKD2_k127_2107132_25 Carbohydrate family 9 binding domain-like - - - 0.0003096 53.0
HKD2_k127_2107132_3 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 348.0
HKD2_k127_2107132_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 347.0
HKD2_k127_2107132_5 Enoyl-CoA hydratase carnithine racemase K01692 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 342.0
HKD2_k127_2107132_6 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 288.0
HKD2_k127_2107132_7 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 283.0
HKD2_k127_2107132_8 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 288.0
HKD2_k127_2107132_9 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007851 304.0
HKD2_k127_211001_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 470.0
HKD2_k127_211001_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 465.0
HKD2_k127_211001_2 - - - - 0.00002568 49.0
HKD2_k127_2118868_0 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 414.0
HKD2_k127_2118868_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000001839 139.0
HKD2_k127_2118868_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000001047 105.0
HKD2_k127_2126423_0 Dehydrogenase E1 component K00164 - 1.2.4.2 2.711e-314 989.0
HKD2_k127_2126423_1 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 402.0
HKD2_k127_2126423_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 335.0
HKD2_k127_2126423_3 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 317.0
HKD2_k127_2126423_4 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000002034 192.0
HKD2_k127_2126423_5 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000000000000000000000000009971 165.0
HKD2_k127_2126423_8 Low-density lipoprotein receptor domain class A - - - 0.0000000000008977 80.0
HKD2_k127_2155548_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 586.0
HKD2_k127_2155548_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 488.0
HKD2_k127_2155548_2 Cytochrome c-type biogenesis protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 386.0
HKD2_k127_2155548_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 302.0
HKD2_k127_2155548_5 - - - - 0.00000000000000000002003 100.0
HKD2_k127_216026_0 Belongs to the pseudouridine synthase RluA family K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003335 296.0
HKD2_k127_216026_1 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000001049 191.0
HKD2_k127_216026_2 Belongs to the serpin family K13963 - - 0.000000000000000002046 87.0
HKD2_k127_216026_3 zinc-ribbon domain - - - 0.0000004372 59.0
HKD2_k127_216472_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 394.0
HKD2_k127_216472_1 - - - - 0.000001175 55.0
HKD2_k127_2187375_0 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 473.0
HKD2_k127_2187375_1 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001524 233.0
HKD2_k127_220709_0 FAD dependent oxidoreductase central domain - - - 0.0 1327.0
HKD2_k127_220709_1 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 546.0
HKD2_k127_220709_10 Tachylectin - - - 0.00000000000000000000000000000000000000004233 166.0
HKD2_k127_220709_11 D-alanyl-D-alanine carboxypeptidase K17733 - - 0.0000000000000000000000000001302 119.0
HKD2_k127_220709_12 polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000003233 100.0
HKD2_k127_220709_13 - - - - 0.00000000000000003559 96.0
HKD2_k127_220709_15 Vault protein inter-alpha-trypsin domain - - - 0.000000000002061 78.0
HKD2_k127_220709_16 guanyl-nucleotide exchange factor activity - - - 0.00000000002344 77.0
HKD2_k127_220709_17 a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans K19355 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004567,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010412,GO:0015923,GO:0016052,GO:0016787,GO:0016798,GO:0016985,GO:0016998,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046355,GO:0071554,GO:0071704,GO:1901575 3.2.1.78 0.0000000005716 71.0
HKD2_k127_220709_18 Parallel beta-helix repeats - - - 0.0000002337 63.0
HKD2_k127_220709_19 Domain of unknown function (DUF4142) K08995 - - 0.00001773 54.0
HKD2_k127_220709_2 Protein kinase domain K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002213 276.0
HKD2_k127_220709_20 NmrA-like family - - - 0.0000264 51.0
HKD2_k127_220709_3 Aldo Keto reductase K01939,K03273,K05275 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 1.1.1.65,3.1.3.82,3.1.3.83,6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000008278 261.0
HKD2_k127_220709_4 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000003358 231.0
HKD2_k127_220709_5 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000002003 214.0
HKD2_k127_220709_6 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000002226 206.0
HKD2_k127_220709_7 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000001743 199.0
HKD2_k127_220709_8 Domain of unknown function (DUF4336) - - - 0.000000000000000000000000000000000000000000000001893 182.0
HKD2_k127_220709_9 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000000000000000000000001519 169.0
HKD2_k127_220841_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 459.0
HKD2_k127_220841_1 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 428.0
HKD2_k127_220841_2 defense response to virus - - - 0.00000000000000000000000000000000000003007 149.0
HKD2_k127_220841_3 PFAM Protein kinase - - - 0.000000000000000000000006883 114.0
HKD2_k127_220841_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000001424 94.0
HKD2_k127_220841_5 helix_turn_helix, arabinose operon control protein K07506 - - 0.0000000000000000003095 95.0
HKD2_k127_220841_6 - - - - 0.00000000000000001906 95.0
HKD2_k127_222380_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 594.0
HKD2_k127_222380_1 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 283.0
HKD2_k127_222380_10 marr family - - - 0.00005146 53.0
HKD2_k127_222380_2 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001246 267.0
HKD2_k127_222380_3 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000004654 264.0
HKD2_k127_222380_4 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000005415 231.0
HKD2_k127_222380_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000009539 211.0
HKD2_k127_222380_6 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000001465 196.0
HKD2_k127_222380_7 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000008604 162.0
HKD2_k127_222380_8 Enoyl-(Acyl carrier protein) reductase K13774 - - 0.0000000000001609 82.0
HKD2_k127_222380_9 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000001286 64.0
HKD2_k127_23304_0 helicase domain protein - - - 4.201e-229 732.0
HKD2_k127_23304_1 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000001164 269.0
HKD2_k127_235112_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 453.0
HKD2_k127_235112_1 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000000002494 177.0
HKD2_k127_235112_2 Endonuclease/Exonuclease/phosphatase family - - - 0.000000191 61.0
HKD2_k127_2372642_0 Belongs to the peptidase S16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 492.0
HKD2_k127_2372642_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 356.0
HKD2_k127_2396231_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 605.0
HKD2_k127_2396231_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003488 274.0
HKD2_k127_2396231_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000007024 251.0
HKD2_k127_2396231_3 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000002008 237.0
HKD2_k127_2396231_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000004749 194.0
HKD2_k127_2396231_5 helix_turn_helix, mercury resistance K22491 - - 0.00000000000000000000000000000000000000000166 167.0
HKD2_k127_2396231_6 peptidase - - - 0.000000000000000000000005134 115.0
HKD2_k127_2488502_1 - - - - 0.00000000000000000000000000000000000000001218 159.0
HKD2_k127_2488502_2 PPIC-type PPIASE domain - - - 0.000000000000000000001905 102.0
HKD2_k127_2488502_3 BON domain - - - 0.00003359 51.0
HKD2_k127_250659_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 458.0
HKD2_k127_250659_1 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000000000000000000000003961 187.0
HKD2_k127_250659_2 SCP-2 sterol transfer family - - - 0.000000000000000000000000007028 124.0
HKD2_k127_250659_4 Signal Transduction Histidine Kinase K03320 - - 0.000000000000000000000003131 105.0
HKD2_k127_250659_5 BON domain - - - 0.00000000000000000003992 98.0
HKD2_k127_250659_6 Peptidoglycan-binding domain 1 protein - - - 0.000000000001345 79.0
HKD2_k127_250659_7 isomerase activity - - - 0.0000001353 63.0
HKD2_k127_250865_0 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000003873 171.0
HKD2_k127_253047_0 IgGFc binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 551.0
HKD2_k127_253047_1 Aldo/keto reductase family - - - 0.000000000000001737 77.0
HKD2_k127_253047_2 COG2931 RTX toxins and related Ca2 -binding - - - 0.0000002533 60.0
HKD2_k127_254885_0 Protein of unknown function (DUF2786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 431.0
HKD2_k127_254885_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 319.0
HKD2_k127_254885_2 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 293.0
HKD2_k127_254885_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000004804 134.0
HKD2_k127_2553232_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001093 237.0
HKD2_k127_2557532_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.414e-240 749.0
HKD2_k127_2557532_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000494 144.0
HKD2_k127_255956_0 Domain of unknown function (DUF4132) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001326 314.0
HKD2_k127_255956_1 luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000001404 237.0
HKD2_k127_255956_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.00000000000000000000000000000000000000000000000000000005845 199.0
HKD2_k127_255956_3 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000002654 188.0
HKD2_k127_255956_4 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.000000000000000000000000000004251 122.0
HKD2_k127_255956_5 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000008173 123.0
HKD2_k127_2560694_0 repeat protein - - - 0.0 1225.0
HKD2_k127_2564399_0 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 347.0
HKD2_k127_2564399_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000349 240.0
HKD2_k127_2564399_2 Cytochrome c - - - 0.0000000000000000000000000000000004518 149.0
HKD2_k127_2564399_3 SPFH domain-Band 7 family - - - 0.000004208 59.0
HKD2_k127_2564399_4 Methyltransferase domain - - - 0.00005266 55.0
HKD2_k127_2576627_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 486.0
HKD2_k127_2576627_1 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 304.0
HKD2_k127_2578503_0 RmlD substrate binding domain K01710,K01784 - 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 447.0
HKD2_k127_2578503_1 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004034 248.0
HKD2_k127_2580478_0 Pfam:Kce K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 611.0
HKD2_k127_2580478_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 366.0
HKD2_k127_2580478_2 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 323.0
HKD2_k127_2580478_3 Belongs to the thiolase family K07508,K17972 GO:0001666,GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006066,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006915,GO:0006950,GO:0006996,GO:0007005,GO:0007006,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008219,GO:0008610,GO:0008637,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009628,GO:0009966,GO:0009968,GO:0009987,GO:0010639,GO:0010646,GO:0010648,GO:0010821,GO:0010823,GO:0010941,GO:0012501,GO:0016042,GO:0016043,GO:0016054,GO:0016125,GO:0016126,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0023051,GO:0023057,GO:0030258,GO:0031974,GO:0032787,GO:0032879,GO:0033043,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034440,GO:0034641,GO:0035383,GO:0035795,GO:0036293,GO:0036294,GO:0042221,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0046395,GO:0046483,GO:0046902,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051179,GO:0051186,GO:0051234,GO:0051716,GO:0055086,GO:0055114,GO:0060548,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071840,GO:0072329,GO:0072521,GO:0090559,GO:1901028,GO:1901029,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902108,GO:1902109,GO:1902652,GO:1902653,GO:1905709,GO:2001233,GO:2001234 2.3.1.16,2.3.1.254 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 295.0
HKD2_k127_2580478_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 323.0
HKD2_k127_2580478_5 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000001434 240.0
HKD2_k127_2599532_0 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 336.0
HKD2_k127_2599532_1 thiamine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002506 283.0
HKD2_k127_2599532_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002497 265.0
HKD2_k127_2599532_3 Glycosyltransferase family 87 - - - 0.00000000000004988 84.0
HKD2_k127_2599532_4 Diacylglycerol acyltransferase - - - 0.000000003758 65.0
HKD2_k127_2606620_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000001663 212.0
HKD2_k127_2606620_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000002329 184.0
HKD2_k127_2606620_2 - - - - 0.00000000000000000000000000000000000001964 158.0
HKD2_k127_2606620_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0002416 44.0
HKD2_k127_2608165_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003275 257.0
HKD2_k127_2608165_1 PEGA domain - - - 0.00000000000000000000000000000000000002321 148.0
HKD2_k127_2608165_2 - - - - 0.00000006439 56.0
HKD2_k127_2608795_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 586.0
HKD2_k127_2608795_1 Transglycosylase SLT domain K08306,K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 439.0
HKD2_k127_2614238_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 1.174e-219 705.0
HKD2_k127_2614238_1 synthase homocitrate synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 406.0
HKD2_k127_2614238_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 328.0
HKD2_k127_2614238_3 Enoyl-CoA hydratase/isomerase K07539 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000000000000000000000000000000000000000000000000006457 196.0
HKD2_k127_2614238_4 SMART Metal-dependent phosphohydrolase, HD region K07141 - 2.7.7.76 0.0005955 49.0
HKD2_k127_2617292_0 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 446.0
HKD2_k127_2617292_1 histone H2A K63-linked ubiquitination K03404,K07114 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000009371 271.0
HKD2_k127_2617292_2 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000000000000000000000000000002835 216.0
HKD2_k127_2617292_3 - - - - 0.000000000000000000000000000000000000000000000000000000000128 232.0
HKD2_k127_2617292_4 histone H2A K63-linked ubiquitination K03404,K07114 - 6.6.1.1 0.0000000000000000000000001624 122.0
HKD2_k127_2617292_6 Rieske 2Fe-2S - - - 0.00000000000000000000000465 108.0
HKD2_k127_2617292_7 histidine kinase A domain protein - - - 0.000000000000004 81.0
HKD2_k127_2619293_0 Domain of unknown function (DUF3488) - - - 3.041e-239 759.0
HKD2_k127_2619293_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 471.0
HKD2_k127_2619293_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 453.0
HKD2_k127_2619293_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 351.0
HKD2_k127_2619293_4 Pkd domain containing protein - - - 0.00003235 55.0
HKD2_k127_2632478_0 GGDEF domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000002266 120.0
HKD2_k127_2632478_1 Sterol carrier protein domain - - - 0.000000000000003315 88.0
HKD2_k127_2632478_2 Sulfatase K01133 - 3.1.6.6 0.00001064 58.0
HKD2_k127_2644190_0 PFAM Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 392.0
HKD2_k127_2644190_1 PFAM Cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000154 203.0
HKD2_k127_2644190_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000005805 113.0
HKD2_k127_2646420_0 cell wall organization K14949 - 2.7.11.1 3.226e-267 909.0
HKD2_k127_2646420_1 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 494.0
HKD2_k127_2646420_2 cell septum assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 356.0
HKD2_k127_2646420_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 346.0
HKD2_k127_2646420_4 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001486 281.0
HKD2_k127_2646420_5 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004638 248.0
HKD2_k127_2646420_7 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000762 178.0
HKD2_k127_2647117_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 7.186e-270 841.0
HKD2_k127_2647117_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 388.0
HKD2_k127_2647117_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003221 267.0
HKD2_k127_2647117_3 GrpB protein - - - 0.000000000000000000000000000001039 128.0
HKD2_k127_2647117_4 Protein of unknown function (DUF2892) - - - 0.0000000000000005025 81.0
HKD2_k127_2649472_0 phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006775 278.0
HKD2_k127_2649472_1 O-acyltransferase activity K00661,K03818 GO:0003674,GO:0003824,GO:0008374,GO:0016740,GO:0016746,GO:0016747 2.3.1.79 0.000000000000000000000000000000000000006971 157.0
HKD2_k127_2649472_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000000001968 147.0
HKD2_k127_2649472_3 O-acyltransferase activity - - - 0.000000000000000000000000000000000005576 144.0
HKD2_k127_2649472_4 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000008739 127.0
HKD2_k127_2650249_0 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 331.0
HKD2_k127_2650249_1 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 325.0
HKD2_k127_2660782_0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 2.106e-246 769.0
HKD2_k127_2660782_1 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 357.0
HKD2_k127_2660782_2 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 345.0
HKD2_k127_2660782_3 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002194 263.0
HKD2_k127_2663414_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 2.365e-260 818.0
HKD2_k127_2663414_1 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 362.0
HKD2_k127_2663414_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 331.0
HKD2_k127_2663414_3 of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000007088 196.0
HKD2_k127_2663414_4 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000000000000000000000000000000004593 208.0
HKD2_k127_2663414_5 Fungal family of unknown function (DUF1776) - - - 0.000000000000000000000000000000000000000000000000005278 195.0
HKD2_k127_2663414_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000004979 158.0
HKD2_k127_2663414_7 Fe-S oxidoreductases - - - 0.0000000000000000000000001664 107.0
HKD2_k127_2666100_0 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 518.0
HKD2_k127_2666100_1 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 308.0
HKD2_k127_2666100_2 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009379 240.0
HKD2_k127_2666100_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000001388 218.0
HKD2_k127_2666100_4 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000006654 155.0
HKD2_k127_2666100_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000004205 139.0
HKD2_k127_2666100_6 DNA-binding transcription factor activity K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000005328 106.0
HKD2_k127_2666100_7 SdpI/YhfL protein family - - - 0.000000000000000000008083 103.0
HKD2_k127_2666386_0 Protein of unknown function, DUF255 K06888 - - 6.213e-222 711.0
HKD2_k127_2666386_1 Heat shock 70 kDa protein K04043 - - 2.289e-221 691.0
HKD2_k127_2666386_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000009427 222.0
HKD2_k127_2666386_12 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000002736 202.0
HKD2_k127_2666386_13 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973,K15257 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000003139 199.0
HKD2_k127_2666386_14 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000003043 190.0
HKD2_k127_2666386_16 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000002704 168.0
HKD2_k127_2666386_17 - - - - 0.0000000000000000000000000000000000000001086 173.0
HKD2_k127_2666386_18 - - - - 0.00000000000000000000000000000000002762 149.0
HKD2_k127_2666386_19 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000003331 128.0
HKD2_k127_2666386_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 611.0
HKD2_k127_2666386_21 Tetratricopeptide repeat - - - 0.0000000000000000000000000642 117.0
HKD2_k127_2666386_22 - - - - 0.0000000000000000000000002274 116.0
HKD2_k127_2666386_23 PilZ domain - - - 0.000000000000000000006193 99.0
HKD2_k127_2666386_25 - - - - 0.000000002314 70.0
HKD2_k127_2666386_27 Dual specificity phosphatase, catalytic domain protein K01090 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.1.3.16 0.00002008 57.0
HKD2_k127_2666386_3 FHA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 472.0
HKD2_k127_2666386_4 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 431.0
HKD2_k127_2666386_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 357.0
HKD2_k127_2666386_6 AAA C-terminal domain K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000898 271.0
HKD2_k127_2666386_7 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001467 259.0
HKD2_k127_2666386_8 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003413 248.0
HKD2_k127_2666386_9 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000001661 237.0
HKD2_k127_2687919_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004068 300.0
HKD2_k127_2687919_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007471 267.0
HKD2_k127_2687919_3 Psort location Cytoplasmic, score K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000003096 205.0
HKD2_k127_2687919_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000002218 189.0
HKD2_k127_2687919_5 Copper binding proteins, plastocyanin/azurin family - GO:0008150,GO:0008152,GO:0055114 - 0.0000000000000000000000000001097 121.0
HKD2_k127_2687919_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000003141 80.0
HKD2_k127_2687919_7 Pectate lyase K01732,K20276 - 4.2.2.10 0.0000000248 67.0
HKD2_k127_2687919_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000001228 61.0
HKD2_k127_2691128_0 General secretion pathway protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000006126 204.0
HKD2_k127_2691128_1 Prokaryotic N-terminal methylation motif K02457 - - 0.00000000000000000000000000000000000000000000001239 180.0
HKD2_k127_2691128_3 general secretion pathway protein K02456 - - 0.00000000000000002457 92.0
HKD2_k127_2699464_0 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000005616 209.0
HKD2_k127_2699464_1 - - - - 0.0000000000000000000000000000000000000000000000000000000003379 207.0
HKD2_k127_2699464_2 - - - - 0.00000000000000000000000000003791 123.0
HKD2_k127_2699464_3 Acid phosphatase homologues - - - 0.0000000000000000000000000007359 124.0
HKD2_k127_2702046_0 AcrB/AcrD/AcrF family K03296,K18138 - - 2.611e-248 782.0
HKD2_k127_2705172_0 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 351.0
HKD2_k127_2705172_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006105 284.0
HKD2_k127_2705172_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003692 254.0
HKD2_k127_2705172_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000002054 192.0
HKD2_k127_2705172_4 Protein of unknown function (DUF1156) - - - 0.0000000000000000000000001731 109.0
HKD2_k127_2717838_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001245 282.0
HKD2_k127_2719028_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 499.0
HKD2_k127_2719028_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000001619 243.0
HKD2_k127_2719028_2 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000008207 211.0
HKD2_k127_2719963_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 481.0
HKD2_k127_2719963_1 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 403.0
HKD2_k127_2719963_2 Ribonuclease E/G family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 364.0
HKD2_k127_2719963_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003293 263.0
HKD2_k127_2719963_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000003533 160.0
HKD2_k127_2719963_5 PilZ domain - - - 0.0000000000000000000000000000000000005386 145.0
HKD2_k127_2719963_6 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000005247 139.0
HKD2_k127_2719963_7 - - - - 0.0000000000134 77.0
HKD2_k127_2722725_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 329.0
HKD2_k127_2722725_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006264 259.0
HKD2_k127_2722725_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000006052 221.0
HKD2_k127_2722725_3 Surface antigen - - - 0.0000000000000000000000000000000000000000005078 174.0
HKD2_k127_2722725_4 - - - - 0.0000000000000000000000000000000000001957 145.0
HKD2_k127_2722725_5 - - - - 0.000000000000001753 87.0
HKD2_k127_2722981_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 614.0
HKD2_k127_2722981_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 425.0
HKD2_k127_2722981_2 enterobactin catabolic process K07214 - - 0.0000000000000000000000000000000000000000000000000000000000003605 227.0
HKD2_k127_2722981_3 TM2 domain - - - 0.000000000000000000000000000000000000004729 145.0
HKD2_k127_2722981_4 - - - - 0.00001443 53.0
HKD2_k127_2751132_0 DNA helicase K03654 - 3.6.4.12 8.932e-206 657.0
HKD2_k127_2751132_1 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 494.0
HKD2_k127_2751132_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 363.0
HKD2_k127_2751132_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 313.0
HKD2_k127_2751132_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000007604 230.0
HKD2_k127_2751132_5 PFAM OsmC family protein K09136 - - 0.00000000000000000000000000000000007343 141.0
HKD2_k127_2751132_6 polysaccharide deacetylase - - - 0.0000000000000000000000000000000008833 150.0
HKD2_k127_2751132_7 - - - - 0.00000000000000000000001043 109.0
HKD2_k127_2758372_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 395.0
HKD2_k127_2758372_1 ATP-grasp K17810 - 6.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 334.0
HKD2_k127_2758372_2 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000349 289.0
HKD2_k127_2758372_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000001259 98.0
HKD2_k127_2759835_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008065 293.0
HKD2_k127_2762753_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 475.0
HKD2_k127_2762753_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 303.0
HKD2_k127_2762753_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004225 247.0
HKD2_k127_2762753_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000001823 173.0
HKD2_k127_2762753_6 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000004343 90.0
HKD2_k127_2762753_7 adenosylhomocysteine nucleosidase activity K01243,K03784,K11783 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.4.2.1,3.2.2.26,3.2.2.9 0.00000000000706 73.0
HKD2_k127_2763344_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.245e-262 818.0
HKD2_k127_2765663_0 Glycosyl hydrolase family 92 - - - 1.233e-199 649.0
HKD2_k127_2765663_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 527.0
HKD2_k127_2765663_10 Domain of unknown function (DUF2383) - - - 0.00000000000000000001297 102.0
HKD2_k127_2765663_2 Protein of unknown function (DUF2515) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003229 275.0
HKD2_k127_2765663_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000001998 185.0
HKD2_k127_2765663_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K15520 - 2.3.1.189 0.000000000000000000000000000000000000001515 156.0
HKD2_k127_2765663_7 Protein of unknown function (DUF1304) K08987 - - 0.00000000000000000000000000000000000005959 148.0
HKD2_k127_2765663_8 - - - - 0.000000000000000000000000000000001598 145.0
HKD2_k127_2765663_9 WGR domain protein - - - 0.00000000000000000000000000004882 130.0
HKD2_k127_2775245_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 287.0
HKD2_k127_2775245_1 S-adenosylhomocysteine deaminase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000008042 240.0
HKD2_k127_2775245_2 - - - - 0.0000000000000001449 93.0
HKD2_k127_2775245_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000003042 58.0
HKD2_k127_2777721_0 protein contain chitin-binding domain type 3 - - - 0.000000000000000000000000000000000000000000000000000000001039 222.0
HKD2_k127_2779664_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 520.0
HKD2_k127_2779664_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 322.0
HKD2_k127_2779664_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000006029 182.0
HKD2_k127_2779664_3 HemY domain protein - - - 0.00000000000000000000000000000000000000000007351 173.0
HKD2_k127_2779664_4 PQQ-like domain - - - 0.0000000000000000000000003579 121.0
HKD2_k127_2786925_0 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 293.0
HKD2_k127_2786925_1 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000005737 229.0
HKD2_k127_2786925_2 energy transducer activity - - - 0.00002688 55.0
HKD2_k127_2793542_0 8-amino-7-oxononanoate synthase activity K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002711 284.0
HKD2_k127_2793542_2 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000000001139 98.0
HKD2_k127_2793542_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000001449 66.0
HKD2_k127_279990_0 protein kinase activity - - - 1.087e-263 822.0
HKD2_k127_279990_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.515e-198 634.0
HKD2_k127_279990_2 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 431.0
HKD2_k127_279990_3 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 431.0
HKD2_k127_279990_4 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 325.0
HKD2_k127_279990_5 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000007973 176.0
HKD2_k127_279990_6 acetyltransferase - - - 0.00000000000000000000000000000001615 135.0
HKD2_k127_279990_8 FR47-like protein - - - 0.000002829 53.0
HKD2_k127_279990_9 - - - - 0.0003393 47.0
HKD2_k127_2802547_0 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 4.375e-266 827.0
HKD2_k127_2840174_0 Domain of unknown function (DUF4132) - - - 1.104e-240 797.0
HKD2_k127_2840174_1 PFAM ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 538.0
HKD2_k127_2840174_10 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000006683 117.0
HKD2_k127_2840174_11 - - - - 0.0000000000000000000003148 113.0
HKD2_k127_2840174_12 protein related to plant photosystem II stability assembly factor - - - 0.00000008395 67.0
HKD2_k127_2840174_2 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 357.0
HKD2_k127_2840174_3 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 347.0
HKD2_k127_2840174_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 295.0
HKD2_k127_2840174_5 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007385 295.0
HKD2_k127_2840174_6 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000009178 279.0
HKD2_k127_2840174_7 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000001156 234.0
HKD2_k127_2840174_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000005286 203.0
HKD2_k127_2840174_9 Antibiotic biosynthesis monooxygenase K09932 - - 0.00000000000000000000000000000000000003761 150.0
HKD2_k127_2845508_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 3.833e-206 658.0
HKD2_k127_2845508_1 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 584.0
HKD2_k127_2845508_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 504.0
HKD2_k127_2845508_3 Family membership K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 323.0
HKD2_k127_2845508_4 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001619 259.0
HKD2_k127_2845508_5 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000211 147.0
HKD2_k127_2845508_6 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000005371 117.0
HKD2_k127_2845508_7 Tetratricopeptide repeat - - - 0.0000000000000000000004305 108.0
HKD2_k127_2845953_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 5.135e-195 634.0
HKD2_k127_2845953_1 Universal stress protein - - - 0.0000161 53.0
HKD2_k127_2848436_0 Pfam:Kce K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 599.0
HKD2_k127_2848436_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 364.0
HKD2_k127_2848436_2 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 340.0
HKD2_k127_2848436_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 327.0
HKD2_k127_2848436_4 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000002555 236.0
HKD2_k127_2848436_5 - - - - 0.000000000000000000000000000000000000000000000002795 179.0
HKD2_k127_2853049_0 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 451.0
HKD2_k127_2853049_1 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 400.0
HKD2_k127_2853049_2 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 309.0
HKD2_k127_2853049_3 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 304.0
HKD2_k127_2853049_4 - - - - 0.0000000000000000000000000000000000000000000000000000000215 208.0
HKD2_k127_2853049_5 Putative diguanylate phosphodiesterase - - - 0.00000000005432 64.0
HKD2_k127_2861630_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001276 285.0
HKD2_k127_2861630_1 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000002829 214.0
HKD2_k127_2861630_4 Thrombospondin type 3 repeat - - - 0.000005058 57.0
HKD2_k127_2867776_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 438.0
HKD2_k127_2867776_1 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001488 250.0
HKD2_k127_2867776_2 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001884 254.0
HKD2_k127_2867776_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000005742 103.0
HKD2_k127_2867776_4 Domain of unknown function (DUF4149) - - - 0.0000000000000000000001227 104.0
HKD2_k127_2870750_0 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003259 229.0
HKD2_k127_2870750_1 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000001563 205.0
HKD2_k127_2870750_2 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000002649 179.0
HKD2_k127_2870750_3 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000001218 130.0
HKD2_k127_290057_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 457.0
HKD2_k127_290057_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 410.0
HKD2_k127_290057_3 - - - - 0.000000000004418 68.0
HKD2_k127_290352_0 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 483.0
HKD2_k127_290352_1 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 462.0
HKD2_k127_290352_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000001198 232.0
HKD2_k127_290352_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000002163 207.0
HKD2_k127_290352_4 - - - - 0.000000000000000000000000000003275 124.0
HKD2_k127_290352_5 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000006265 54.0
HKD2_k127_2906470_0 CoA-substrate-specific enzyme activase - - - 0.0 1529.0
HKD2_k127_2906470_1 4 iron, 4 sulfur cluster binding - - - 6.753e-232 732.0
HKD2_k127_2906470_2 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 567.0
HKD2_k127_2906470_3 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 439.0
HKD2_k127_2906470_4 CoA-substrate-specific enzyme activase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 385.0
HKD2_k127_2906470_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 384.0
HKD2_k127_2906470_6 Proposed nucleic acid binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002412 268.0
HKD2_k127_2906470_7 Transcription elongation factor, GreA/GreB, C-term - - - 0.000000000000000000000003004 108.0
HKD2_k127_2911159_0 Protein phosphatase 2A homologues, catalytic domain. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 386.0
HKD2_k127_2911159_1 Flavodoxin-like fold K00355 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001652 282.0
HKD2_k127_2911159_2 Cupin domain - - - 0.00000000000000000000000000000000000001202 148.0
HKD2_k127_2911159_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000004083 96.0
HKD2_k127_2911159_4 Helix-turn-helix domain - - - 0.0001216 51.0
HKD2_k127_2911460_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 347.0
HKD2_k127_2911460_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000005641 170.0
HKD2_k127_2918405_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 8.444e-286 889.0
HKD2_k127_2918405_1 COGs COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 497.0
HKD2_k127_2918405_2 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 380.0
HKD2_k127_2918405_3 Domain of unknown function (DUF4132) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 323.0
HKD2_k127_2918405_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 302.0
HKD2_k127_2918405_5 FHA domain - - - 0.00000000000000000000000000000000000000000000000007242 190.0
HKD2_k127_2918405_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000004855 169.0
HKD2_k127_2918846_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 339.0
HKD2_k127_2918846_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000001203 65.0
HKD2_k127_2919673_0 von Willebrand factor (vWF) type A domain - - - 4.891e-261 816.0
HKD2_k127_2919673_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 632.0
HKD2_k127_2919673_11 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000001284 81.0
HKD2_k127_2919673_12 PFAM Bacterial Ig-like domain (group 2) - - - 0.0000009663 61.0
HKD2_k127_2919673_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001025 296.0
HKD2_k127_2919673_3 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004587 289.0
HKD2_k127_2919673_4 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001516 293.0
HKD2_k127_2919673_5 - - - - 0.000000000000000000000000000000000000000000000000000000000718 231.0
HKD2_k127_2919673_6 - - - - 0.00000000000000000000000000000000000000000000000000000004974 211.0
HKD2_k127_2919673_7 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000001535 195.0
HKD2_k127_2919673_8 - - - - 0.00000000000000000000000000000000000001045 159.0
HKD2_k127_2919673_9 - - - - 0.00000000000000000003053 99.0
HKD2_k127_2928307_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 593.0
HKD2_k127_2928307_1 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 385.0
HKD2_k127_2928307_2 - - - - 0.000000000000000000000000000000000000000000000000000000003798 221.0
HKD2_k127_2928307_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000002882 101.0
HKD2_k127_2928307_4 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000001945 70.0
HKD2_k127_2938261_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 329.0
HKD2_k127_2938261_1 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000001667 185.0
HKD2_k127_2938261_2 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000479 182.0
HKD2_k127_2938261_3 amine dehydrogenase activity - - - 0.0000000000000001486 94.0
HKD2_k127_2938261_5 - - - - 0.00000002979 66.0
HKD2_k127_295131_0 nitrous-oxide reductase activity K00376 - 1.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 377.0
HKD2_k127_295131_1 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 327.0
HKD2_k127_295131_2 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 306.0
HKD2_k127_295131_3 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000002604 259.0
HKD2_k127_295131_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000005786 179.0
HKD2_k127_295131_5 Cytochrome c - - - 0.000000000000000000000000003578 127.0
HKD2_k127_295131_6 ATP ADP translocase K03301 - - 0.0000000000001493 74.0
HKD2_k127_295131_7 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000002657 69.0
HKD2_k127_2991210_0 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 445.0
HKD2_k127_2991210_1 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 330.0
HKD2_k127_2991210_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 321.0
HKD2_k127_2991210_3 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 302.0
HKD2_k127_2991210_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000003265 244.0
HKD2_k127_2991210_5 aminopeptidase activity K19689 - - 0.000000000000000000000000000000000000000000000000000000000000005707 233.0
HKD2_k127_2991210_6 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000002917 133.0
HKD2_k127_2991210_7 - - - - 0.000000000000000000000002281 108.0
HKD2_k127_2991210_8 cellulase activity - - - 0.000000000000000005986 97.0
HKD2_k127_2991210_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000003269 57.0
HKD2_k127_2996740_0 glycoside hydrolase family 2 sugar binding K01192 - 3.2.1.25 1.617e-221 713.0
HKD2_k127_2996740_1 Glycoside hydrolase family 44 - - - 6.871e-195 630.0
HKD2_k127_2996740_10 Major Facilitator Superfamily K03446 - - 0.0000000000000000000000000000000000000000000000001156 183.0
HKD2_k127_2996740_11 polysaccharide export K01991 - - 0.00000000000000000000000000000000000000001926 159.0
HKD2_k127_2996740_12 transferase activity, transferring acyl groups - - - 0.000000000000000000000000000000000000005023 166.0
HKD2_k127_2996740_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 519.0
HKD2_k127_2996740_3 seryl-tRNA synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 416.0
HKD2_k127_2996740_4 Domain of unknown function (DUF1839) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 347.0
HKD2_k127_2996740_5 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000345 286.0
HKD2_k127_2996740_6 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004598 282.0
HKD2_k127_2996740_7 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000001339 239.0
HKD2_k127_2996740_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000003468 209.0
HKD2_k127_2996740_9 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.000000000000000000000000000000000000000000000000003193 195.0
HKD2_k127_3001689_0 two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 436.0
HKD2_k127_3001689_1 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 343.0
HKD2_k127_3001689_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 324.0
HKD2_k127_3001689_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001662 283.0
HKD2_k127_3001689_5 - - - - 0.0000000000000000000000000000001368 131.0
HKD2_k127_3001689_6 - - - - 0.00000000000000000000000003573 112.0
HKD2_k127_3001689_7 Bacterial pre-peptidase C-terminal domain K14645 - - 0.00000000000001066 87.0
HKD2_k127_3002273_0 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 531.0
HKD2_k127_3002273_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 325.0
HKD2_k127_3002273_2 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.0000000000000000000000000095 123.0
HKD2_k127_3011610_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.179e-212 666.0
HKD2_k127_3011610_1 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001871 271.0
HKD2_k127_3011610_2 - - - - 0.00000000000000000000000000000000000000000000000000002054 192.0
HKD2_k127_3016826_0 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 388.0
HKD2_k127_3016826_1 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 385.0
HKD2_k127_3016826_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000004314 55.0
HKD2_k127_3016826_3 Diguanylate cyclase phosphodiesterase with PAS - - - 0.00004389 56.0
HKD2_k127_3026652_0 GTP-binding protein K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 499.0
HKD2_k127_3026652_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 417.0
HKD2_k127_3026652_10 GRAM domain - - - 0.0000000000000000142 85.0
HKD2_k127_3026652_11 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.00000000000006562 78.0
HKD2_k127_3026652_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 389.0
HKD2_k127_3026652_4 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 314.0
HKD2_k127_3026652_5 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000926 259.0
HKD2_k127_3026652_6 phospholipase C K21302 - 3.1.3.64 0.0000000000000000000000000000000000000002742 162.0
HKD2_k127_3026652_7 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000006879 129.0
HKD2_k127_3026652_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000007847 104.0
HKD2_k127_3052556_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 457.0
HKD2_k127_3052556_2 - - - - 0.00000004857 57.0
HKD2_k127_3069975_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 352.0
HKD2_k127_3069975_1 membrane-bound metal-dependent K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000005553 164.0
HKD2_k127_3069975_2 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000464 98.0
HKD2_k127_3069975_3 - - - - 0.00000000000003023 75.0
HKD2_k127_3076978_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 338.0
HKD2_k127_3076978_2 deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000001797 240.0
HKD2_k127_3076978_3 Cell wall formation K00075,K01921 - 1.3.1.98,6.3.2.4 0.0000000000000000000000000000000000000000000000000000004644 208.0
HKD2_k127_3076978_4 SMART serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000002678 122.0
HKD2_k127_3085161_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007664 545.0
HKD2_k127_3085161_1 - - - - 0.0000000000000000000000006125 115.0
HKD2_k127_3085161_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000005459 95.0
HKD2_k127_3085161_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000004863 88.0
HKD2_k127_3085161_4 Putative Ig domain - - - 0.0000000175 65.0
HKD2_k127_3094593_0 protein kinase activity K12132 - 2.7.11.1 0.00000000000001751 82.0
HKD2_k127_310574_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.0000000000000000005698 88.0
HKD2_k127_310574_1 PFAM SMP-30 Gluconolaconase - - - 0.0000000005644 66.0
HKD2_k127_3111867_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 427.0
HKD2_k127_3111867_1 conserved protein (DUF2183) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 368.0
HKD2_k127_3111867_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000004823 187.0
HKD2_k127_3121437_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1184.0
HKD2_k127_3121437_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 336.0
HKD2_k127_3121437_2 4-vinyl reductase, 4VR K06382,K07013 - 3.1.3.16 0.0000000000000000000000000000000000000000000000001276 198.0
HKD2_k127_3121437_3 phosphatase homologous to the C-terminal domain of histone macroH2A1 - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000003237 172.0
HKD2_k127_3127062_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 4.531e-201 651.0
HKD2_k127_3127062_1 very-long-chain enoyl-CoA reductase activity K05658,K10258 GO:0000038,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005783,GO:0005789,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016631,GO:0019752,GO:0030497,GO:0031224,GO:0031984,GO:0032787,GO:0042175,GO:0042761,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0072330,GO:0098827,GO:1901576 1.3.1.93,3.6.3.44 0.000000000000000000000000000000000000000000008476 169.0
HKD2_k127_3127062_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000002694 137.0
HKD2_k127_3127062_3 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.000000000000000001756 95.0
HKD2_k127_313859_0 YaeQ - - - 0.0000000000000000000000000000000000000000000000591 174.0
HKD2_k127_313859_1 Alpha beta hydrolase - - - 0.00000000000000002622 94.0
HKD2_k127_313859_2 Tetratricopeptide repeat - - - 0.000001277 56.0
HKD2_k127_316001_0 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 354.0
HKD2_k127_316001_1 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000005864 160.0
HKD2_k127_316001_2 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000001254 154.0
HKD2_k127_316001_3 - - - - 0.0000000000000000000000000002291 121.0
HKD2_k127_316001_4 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000002115 103.0
HKD2_k127_316001_5 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.000000000000000005306 96.0
HKD2_k127_3163703_0 Histidine ammonia-lyase K01745 - 4.3.1.3 1.855e-202 663.0
HKD2_k127_3163703_2 lipolytic protein G-D-S-L family K00612 - - 0.0000000000000008063 91.0
HKD2_k127_3167717_0 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 378.0
HKD2_k127_3167717_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000119 166.0
HKD2_k127_3167717_4 FCD - - - 0.0000000000001051 77.0
HKD2_k127_3169164_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 404.0
HKD2_k127_3169164_1 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000003674 254.0
HKD2_k127_3169164_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000811 244.0
HKD2_k127_3169164_3 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000002473 252.0
HKD2_k127_3169164_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000001149 217.0
HKD2_k127_3169164_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000001231 184.0
HKD2_k127_3169164_6 - - - - 0.00000000000000000000002801 112.0
HKD2_k127_3169164_7 peptidyl-tyrosine sulfation - - - 0.00000000003407 76.0
HKD2_k127_3191825_1 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000003247 169.0
HKD2_k127_3191825_2 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000001692 160.0
HKD2_k127_3191825_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000002017 151.0
HKD2_k127_3191825_5 Belongs to the MEMO1 family K06990 - - 0.0001078 46.0
HKD2_k127_320225_0 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 414.0
HKD2_k127_320225_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 395.0
HKD2_k127_320225_2 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000004709 198.0
HKD2_k127_320225_3 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000008543 114.0
HKD2_k127_3206448_0 periplasmic copper-binding protein NosD K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007065 281.0
HKD2_k127_3206448_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000001137 137.0
HKD2_k127_3206448_2 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 0.00000000000000000000000000001871 118.0
HKD2_k127_320649_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000008059 171.0
HKD2_k127_320649_1 Acyl-ACP thioesterase K07107 - - 0.0000000000000000000000000000000000001187 145.0
HKD2_k127_320649_2 oligosaccharyl transferase activity - - - 0.00000000000259 71.0
HKD2_k127_320649_3 PFAM Helix-turn-helix - - - 0.00000001646 58.0
HKD2_k127_3207542_0 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000003465 248.0
HKD2_k127_3207542_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000001121 174.0
HKD2_k127_3207542_2 Methyltransferase domain - - - 0.00000000000003526 79.0
HKD2_k127_321306_0 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 334.0
HKD2_k127_321306_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000001386 226.0
HKD2_k127_321306_2 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000002019 122.0
HKD2_k127_326517_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 599.0
HKD2_k127_326517_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 547.0
HKD2_k127_326517_10 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000001219 222.0
HKD2_k127_326517_14 - - - - 0.00000000000000000000000000000000007401 148.0
HKD2_k127_326517_15 4Fe-4S binding domain - - - 0.000000000000000000000000000000286 130.0
HKD2_k127_326517_17 protein kinase activity - - - 0.00000000000000000000000000007033 135.0
HKD2_k127_326517_18 - - - - 0.000000000005278 79.0
HKD2_k127_326517_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 464.0
HKD2_k127_326517_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 417.0
HKD2_k127_326517_4 Two component transcriptional regulator, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 331.0
HKD2_k127_326517_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 308.0
HKD2_k127_326517_6 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003643 273.0
HKD2_k127_326517_7 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008475 250.0
HKD2_k127_326517_8 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000000000000000000000000000000000000000000000000000000000002063 242.0
HKD2_k127_326517_9 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000000000000000000000000000000000000000000000000000000005106 218.0
HKD2_k127_328154_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 546.0
HKD2_k127_3294574_0 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 319.0
HKD2_k127_3294574_1 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000007613 191.0
HKD2_k127_3294574_2 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000007405 110.0
HKD2_k127_3296221_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 456.0
HKD2_k127_3296221_1 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 362.0
HKD2_k127_3296221_10 SnoaL-like polyketide cyclase - - - 0.0000005457 61.0
HKD2_k127_3296221_11 response regulator - - - 0.00000171 59.0
HKD2_k127_3296221_12 NnrS protein K07234 - - 0.00004038 57.0
HKD2_k127_3296221_2 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 340.0
HKD2_k127_3296221_3 Non-ribosomal peptide synthetase modules and related proteins K04780 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000747 325.0
HKD2_k127_3296221_4 COG1063 Threonine dehydrogenase and related Zn-dependent - - - 0.000000000000000000000000000000000000000000000001205 184.0
HKD2_k127_3296221_5 Von willebrand factor, type a - - - 0.000000000000000000000000000000000000002596 166.0
HKD2_k127_3296221_6 - - - - 0.00000000000000000000000003512 119.0
HKD2_k127_3296221_9 oxidoreductase activity K07114 - - 0.0000002215 64.0
HKD2_k127_3301142_0 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000001301 222.0
HKD2_k127_3301142_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000001021 179.0
HKD2_k127_3301142_2 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000004957 179.0
HKD2_k127_331280_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 321.0
HKD2_k127_331280_1 PEGA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002208 292.0
HKD2_k127_331280_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007076 278.0
HKD2_k127_331280_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001899 230.0
HKD2_k127_331280_7 Stigma-specific protein, Stig1 - - - 0.00000000003474 76.0
HKD2_k127_3320632_0 type IV pilus secretin PilQ K02666 - - 2.758e-268 848.0
HKD2_k127_3320632_1 IgGFc binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 550.0
HKD2_k127_3320632_10 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000000000000000000000003335 161.0
HKD2_k127_3320632_11 Sigma-70, region 4 K02405 - - 0.00000000000000000000000000000000000000004954 158.0
HKD2_k127_3320632_12 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000007446 161.0
HKD2_k127_3320632_13 Bacterial PH domain - - - 0.000000000000000000000000000004868 126.0
HKD2_k127_3320632_14 lipid binding - - - 0.000002451 60.0
HKD2_k127_3320632_15 PFAM Aminotransferase class I and II - - - 0.000003059 53.0
HKD2_k127_3320632_2 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 442.0
HKD2_k127_3320632_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 304.0
HKD2_k127_3320632_4 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002939 265.0
HKD2_k127_3320632_6 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002579 259.0
HKD2_k127_3320632_7 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000000000008768 214.0
HKD2_k127_3320632_8 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000000001887 199.0
HKD2_k127_3322725_0 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 529.0
HKD2_k127_3322725_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000004823 232.0
HKD2_k127_3322725_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000005654 171.0
HKD2_k127_3322725_3 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000000000000000000000003695 128.0
HKD2_k127_3322725_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000001571 87.0
HKD2_k127_3322725_5 Methyltransferase type 12 - - - 0.000000000002694 79.0
HKD2_k127_3373960_1 dihydrofolate reductase activity - - - 0.000000000000000000000000000000002146 132.0
HKD2_k127_3373960_2 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000002321 134.0
HKD2_k127_3373960_3 - - - - 0.000000000000000000000006692 113.0
HKD2_k127_3393812_0 Vault protein inter-alpha-trypsin domain - - - 3.016e-240 789.0
HKD2_k127_3393812_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000002711 148.0
HKD2_k127_3393812_2 InterPro IPR007367 - - - 0.0000000000000000000000000000001146 126.0
HKD2_k127_3393812_3 Stress-induced bacterial acidophilic repeat motif K06884 - - 0.00000000007081 71.0
HKD2_k127_3393812_4 MarR family - - - 0.000000001208 68.0
HKD2_k127_3402542_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.535e-197 625.0
HKD2_k127_3402542_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 611.0
HKD2_k127_3402542_10 Helix-hairpin-helix motif K02237 - - 0.000000000000002537 82.0
HKD2_k127_3402542_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 421.0
HKD2_k127_3402542_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 292.0
HKD2_k127_3402542_4 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000003367 258.0
HKD2_k127_3402542_5 anaphase-promoting complex binding K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002642 265.0
HKD2_k127_3402542_6 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000005752 234.0
HKD2_k127_3402542_7 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000001404 237.0
HKD2_k127_3402542_8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000779 234.0
HKD2_k127_3402542_9 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000001174 118.0
HKD2_k127_3416081_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009155 610.0
HKD2_k127_3416081_1 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 587.0
HKD2_k127_3416081_11 protein conserved in bacteria (DUF2062) K09928 - - 0.0000001935 65.0
HKD2_k127_3416081_2 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 473.0
HKD2_k127_3416081_3 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 411.0
HKD2_k127_3416081_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 348.0
HKD2_k127_3416081_5 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 341.0
HKD2_k127_3416081_6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 303.0
HKD2_k127_3416081_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000002878 196.0
HKD2_k127_3416081_8 - - - - 0.00000000000000000001446 97.0
HKD2_k127_3416081_9 - - - - 0.000000000000006716 87.0
HKD2_k127_3442726_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 373.0
HKD2_k127_3442726_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000001572 106.0
HKD2_k127_3442726_3 Mut7-C RNAse domain K09122 - - 0.000000006705 57.0
HKD2_k127_3443405_0 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 377.0
HKD2_k127_3443405_3 fatty acid desaturase - - - 0.000000000000000003588 85.0
HKD2_k127_3443405_4 Bacterial protein of unknown function (DUF882) - - - 0.000007976 48.0
HKD2_k127_3443988_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000009115 222.0
HKD2_k127_3446054_0 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001072 256.0
HKD2_k127_3446054_1 luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000004499 225.0
HKD2_k127_3446054_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000001361 224.0
HKD2_k127_3446054_3 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000004526 202.0
HKD2_k127_3446054_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000007759 187.0
HKD2_k127_3446054_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000002072 106.0
HKD2_k127_3446054_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000005746 110.0
HKD2_k127_3446054_8 BFD-like [2Fe-2S] binding domain K02192 - - 0.0000000003735 64.0
HKD2_k127_3446054_9 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0001301 52.0
HKD2_k127_3479870_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 489.0
HKD2_k127_3479870_1 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 314.0
HKD2_k127_3479870_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006349 284.0
HKD2_k127_3479870_3 YbbR-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003444 265.0
HKD2_k127_3479870_4 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000008079 167.0
HKD2_k127_3479870_5 Transcriptional regulator - - - 0.00000000000000000000000000002736 122.0
HKD2_k127_3479870_6 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000125 113.0
HKD2_k127_3494212_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.099e-195 639.0
HKD2_k127_3494212_1 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 539.0
HKD2_k127_3494212_11 Belongs to the glycosyl hydrolase 2 family - - - 0.000001265 61.0
HKD2_k127_3494212_2 MCM2/3/5 family K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 469.0
HKD2_k127_3494212_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 432.0
HKD2_k127_3494212_4 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 428.0
HKD2_k127_3494212_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001187 270.0
HKD2_k127_3494212_7 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000124 252.0
HKD2_k127_3494212_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000001053 246.0
HKD2_k127_3494212_9 EamA-like transporter family - - - 0.00000000000000000002619 103.0
HKD2_k127_3497566_0 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 602.0
HKD2_k127_3497566_1 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 517.0
HKD2_k127_3497566_2 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 370.0
HKD2_k127_3497566_3 Beta-lactamase - - - 0.000000000000000000000000000004029 133.0
HKD2_k127_3497566_4 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.00000000000009886 85.0
HKD2_k127_3498865_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.386e-203 661.0
HKD2_k127_3498865_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 373.0
HKD2_k127_3498865_2 Transcriptional Regulator, AraC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002064 262.0
HKD2_k127_3498865_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000005773 173.0
HKD2_k127_3498865_5 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000000000005289 101.0
HKD2_k127_3541597_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 464.0
HKD2_k127_3541597_1 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000006006 230.0
HKD2_k127_3541597_2 ABC transporter K15738 - - 0.00000004411 63.0
HKD2_k127_354910_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009376 593.0
HKD2_k127_354910_1 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000001062 239.0
HKD2_k127_3553913_0 Cytochrome c554 and c-prime - - - 8.409e-279 885.0
HKD2_k127_3553913_1 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 2.164e-205 654.0
HKD2_k127_3553913_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 497.0
HKD2_k127_3553913_3 Protein kinase domain K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 373.0
HKD2_k127_3553913_4 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 370.0
HKD2_k127_3553913_5 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 357.0
HKD2_k127_3553913_6 Fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 329.0
HKD2_k127_3553913_7 NUDIX hydrolase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000001848 183.0
HKD2_k127_3553913_8 4Fe-4S dicluster domain - - - 0.00000000000000000000000000002683 137.0
HKD2_k127_3561961_0 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 1.368e-261 828.0
HKD2_k127_3561961_1 AMP-binding enzyme K12508 - 6.2.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 568.0
HKD2_k127_3561961_10 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000001363 169.0
HKD2_k127_3561961_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000461 114.0
HKD2_k127_3561961_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000002722 104.0
HKD2_k127_3561961_13 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000002888 96.0
HKD2_k127_3561961_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 451.0
HKD2_k127_3561961_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 452.0
HKD2_k127_3561961_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 366.0
HKD2_k127_3561961_5 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001723 287.0
HKD2_k127_3561961_6 phosphogluconate dehydrogenase (decarboxylating) activity K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004355 309.0
HKD2_k127_3561961_7 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000007474 254.0
HKD2_k127_3561961_8 Protein conserved in bacteria K09986 - - 0.000000000000000000000000000000000000000000000004369 177.0
HKD2_k127_3561961_9 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000003191 183.0
HKD2_k127_356434_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 6.469e-203 648.0
HKD2_k127_356434_1 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 619.0
HKD2_k127_356434_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K13890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 321.0
HKD2_k127_356434_3 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000005563 209.0
HKD2_k127_356434_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000002469 143.0
HKD2_k127_356434_5 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000002347 92.0
HKD2_k127_356434_6 Parallel beta-helix repeats - - - 0.00000000000000000005348 101.0
HKD2_k127_3578608_0 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000008631 211.0
HKD2_k127_3578608_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000005372 152.0
HKD2_k127_3578608_2 Aminotransferase - - - 0.0000000000000000000000696 98.0
HKD2_k127_3584164_0 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000002174 159.0
HKD2_k127_3584164_1 - - - - 0.00002646 56.0
HKD2_k127_3585497_0 Alanine racemase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 315.0
HKD2_k127_3585497_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000142 84.0
HKD2_k127_3600186_0 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 442.0
HKD2_k127_3600186_1 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 306.0
HKD2_k127_363443_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 502.0
HKD2_k127_363443_1 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 352.0
HKD2_k127_363443_2 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 294.0
HKD2_k127_363443_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000003438 193.0
HKD2_k127_363443_5 AMP binding - - - 0.000000000000000000000000008575 115.0
HKD2_k127_363443_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000003687 109.0
HKD2_k127_363443_7 - - - - 0.00000000000000007855 94.0
HKD2_k127_363443_8 Beta-L-arabinofuranosidase, GH127 - - - 0.000000008812 67.0
HKD2_k127_363443_9 Fe2 -dicitrate sensor, membrane component K07165 - - 0.0003298 53.0
HKD2_k127_3656122_0 amine dehydrogenase activity - - - 0.00002717 56.0
HKD2_k127_3656122_1 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.0009501 52.0
HKD2_k127_3659924_0 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000005006 181.0
HKD2_k127_3659924_1 - - - - 0.0000000000000000000000000000000000000004171 160.0
HKD2_k127_3659924_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000037 134.0
HKD2_k127_3659924_3 - - - - 0.0000000000001259 78.0
HKD2_k127_367266_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 309.0
HKD2_k127_367266_1 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 315.0
HKD2_k127_367266_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000001207 137.0
HKD2_k127_370000_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 328.0
HKD2_k127_370000_1 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 299.0
HKD2_k127_370000_2 Putative RNA methylase family UPF0020 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008628 278.0
HKD2_k127_370000_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001221 248.0
HKD2_k127_370000_4 Protein conserved in bacteria K09939 - - 0.000000000000000000000000000000000000000000000000000000000000001184 226.0
HKD2_k127_370000_6 - - - - 0.000000000000029 87.0
HKD2_k127_370000_8 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.000000000005334 73.0
HKD2_k127_370000_9 COG1520 FOG WD40-like repeat K17713 - - 0.00000138 61.0
HKD2_k127_374592_0 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 290.0
HKD2_k127_374592_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002901 279.0
HKD2_k127_37564_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 424.0
HKD2_k127_37564_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 347.0
HKD2_k127_37564_10 Belongs to the ompA family K03640 - - 0.00000000000000000000000000001051 126.0
HKD2_k127_37564_11 Histidine kinase K07675,K20263 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000002766 111.0
HKD2_k127_37564_12 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000003137 102.0
HKD2_k127_37564_13 - - - - 0.0000000000000001653 81.0
HKD2_k127_37564_14 - - - - 0.000000000000006825 85.0
HKD2_k127_37564_16 response regulator - - - 0.000000001226 64.0
HKD2_k127_37564_17 PhoQ Sensor - - - 0.00000001444 67.0
HKD2_k127_37564_18 Epidermal growth factor-like domain. - GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.0000001179 63.0
HKD2_k127_37564_19 PFAM regulatory protein LuxR - - - 0.00000565 54.0
HKD2_k127_37564_2 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 328.0
HKD2_k127_37564_20 Sulfate transporter K03321 - - 0.000008018 58.0
HKD2_k127_37564_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 320.0
HKD2_k127_37564_4 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000647 256.0
HKD2_k127_37564_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004046 268.0
HKD2_k127_37564_6 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000000000000000000000000000000000000000000000008324 206.0
HKD2_k127_37564_7 Rossmann-like domain K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000328 197.0
HKD2_k127_37564_8 virulence factor implicated in the pathogenesis of mycobacterium tuberculosis at the level of intracellular survival, by the alteration of cell signaling events or by direct cytotoxicity catalytic activity a phosphatidylcholine H(2)O 1,2- diacylglycerol choline phosphate K01114 GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006629,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009405,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0034480,GO:0035821,GO:0042578,GO:0044003,GO:0044238,GO:0044403,GO:0044419,GO:0044464,GO:0051701,GO:0051704,GO:0051817,GO:0052008,GO:0052043,GO:0052111,GO:0052185,GO:0052188,GO:0052368,GO:0071704,GO:0071944,GO:1901575 3.1.4.3 0.00000000000000000000000000000000000000000000007603 186.0
HKD2_k127_37564_9 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000001799 147.0
HKD2_k127_377901_0 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 347.0
HKD2_k127_377901_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 327.0
HKD2_k127_377901_2 PFAM PHP domain protein K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000004015 267.0
HKD2_k127_377901_3 Diacylglycerol acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001984 243.0
HKD2_k127_377901_4 Major facilitator superfamily - - - 0.00000000000000000000002632 117.0
HKD2_k127_37942_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.113e-232 731.0
HKD2_k127_37942_1 Zinc finger, swim domain protein - - - 3.645e-221 699.0
HKD2_k127_37942_10 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000000000009566 139.0
HKD2_k127_37942_2 RNA-directed DNA polymerase K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 532.0
HKD2_k127_37942_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 398.0
HKD2_k127_37942_4 Dyp-type peroxidase family K07223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 291.0
HKD2_k127_37942_5 Vitamin k epoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002823 293.0
HKD2_k127_37942_6 Bacterial transcriptional repressor C-terminal K16137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007354 256.0
HKD2_k127_37942_7 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000000000000000000000000000000000000000000000001102 231.0
HKD2_k127_37942_8 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001653 246.0
HKD2_k127_37942_9 COG2346, Truncated hemoglobins K06886 - - 0.000000000000000000000000000000000000006865 149.0
HKD2_k127_3835923_0 ABC transporter, ATP-binding protein K01990 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0022857,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 6.745e-269 843.0
HKD2_k127_3835923_1 amino acid K03294 - - 8.778e-195 641.0
HKD2_k127_3835923_2 ABC-2 family transporter protein K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 496.0
HKD2_k127_3835923_3 ABC-2 family transporter protein K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 498.0
HKD2_k127_3835923_4 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 353.0
HKD2_k127_3835923_5 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005312 238.0
HKD2_k127_3835923_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.0000000000000000000000000000000000000000002126 160.0
HKD2_k127_3835923_7 LysR substrate binding domain K18297 - - 0.0000000000000000000002368 98.0
HKD2_k127_3836763_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 586.0
HKD2_k127_3836763_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 503.0
HKD2_k127_3836763_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 487.0
HKD2_k127_3836763_3 TatD related DNase K07051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 401.0
HKD2_k127_3836763_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 363.0
HKD2_k127_3836763_5 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001043 285.0
HKD2_k127_3836763_6 - - - - 0.00000000000000000000000000000000007182 146.0
HKD2_k127_3836763_7 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000001162 138.0
HKD2_k127_3836763_8 Tetratricopeptide repeat - - - 0.00000000000000000000663 98.0
HKD2_k127_3836763_9 DEAD DEAH box helicase K03724 - - 0.000000000000000001759 87.0
HKD2_k127_3837845_0 Von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 485.0
HKD2_k127_3837845_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 472.0
HKD2_k127_3837845_2 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001379 253.0
HKD2_k127_3837845_3 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000006497 183.0
HKD2_k127_3838174_0 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005804 286.0
HKD2_k127_3838174_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000834 171.0
HKD2_k127_3838174_3 phosphorelay signal transduction system K01338 - 3.4.21.53 0.00000377 49.0
HKD2_k127_3849486_0 heat shock protein binding K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 316.0
HKD2_k127_3849486_1 belongs to the thioredoxin family K03671,K05838,K07390,K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 300.0
HKD2_k127_3849486_2 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000004072 208.0
HKD2_k127_3849486_3 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000003624 176.0
HKD2_k127_3849486_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000001953 181.0
HKD2_k127_3853938_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 6.162e-218 685.0
HKD2_k127_3853938_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 404.0
HKD2_k127_3853938_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008349 278.0
HKD2_k127_3853938_3 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001358 260.0
HKD2_k127_3853938_4 - - - - 0.00000000000000000000000000000000000000002587 158.0
HKD2_k127_3853938_5 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.0000000000000000000002189 109.0
HKD2_k127_3853938_6 acid phosphatase activity K03651 - 3.1.4.53 0.0000003936 62.0
HKD2_k127_3853938_8 PFAM regulatory protein, MarR - - - 0.00009437 51.0
HKD2_k127_3856559_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620,K00930 - 2.3.1.1,2.3.1.35,2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 494.0
HKD2_k127_3856559_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000132 258.0
HKD2_k127_3858849_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 533.0
HKD2_k127_3858849_1 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 310.0
HKD2_k127_3858849_2 k transport K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002781 282.0
HKD2_k127_3859405_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 436.0
HKD2_k127_3859405_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 393.0
HKD2_k127_3859405_2 - - - - 0.00000000000000000000000001099 112.0
HKD2_k127_3859405_3 Tetratricopeptide repeat - - - 0.0000000000000000000000005039 108.0
HKD2_k127_3861638_0 N-terminal domain of unknown function (DUF4140) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 336.0
HKD2_k127_3861638_1 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000000000001546 210.0
HKD2_k127_3863227_0 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000003487 214.0
HKD2_k127_3863227_1 Outer membrane efflux protein - - - 0.00000000000000000000000165 117.0
HKD2_k127_387324_0 MMPL family K07003 - - 3.123e-194 643.0
HKD2_k127_387324_1 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 571.0
HKD2_k127_3873554_0 Cyclic nucleotide-monophosphate binding domain K03301 - - 0.00000000000000000000002145 113.0
HKD2_k127_3873554_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000122 100.0
HKD2_k127_3874668_0 kinase activity K01007 - 2.7.9.2 2.706e-242 778.0
HKD2_k127_3874668_1 Sulfatase-modifying factor enzyme 1 K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 408.0
HKD2_k127_3874668_2 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002211 291.0
HKD2_k127_3874668_3 Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair K03573 GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009036,GO:0009987,GO:0015666,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019219,GO:0019222,GO:0031323,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0043765,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000002152 226.0
HKD2_k127_3874668_4 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000001836 235.0
HKD2_k127_3874668_5 pseudouridine synthase activity K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000003918 171.0
HKD2_k127_3874668_6 SEC-C Motif Domain Protein K09858 - - 0.0000000000000000000000000000008916 126.0
HKD2_k127_3874668_7 ATP ADP translocase K03301 - - 0.000000000000000000001274 106.0
HKD2_k127_3874668_9 Uncharacterized conserved protein (COG2071) K09166 - - 0.00005115 53.0
HKD2_k127_3878290_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 394.0
HKD2_k127_3878290_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 396.0
HKD2_k127_3878290_10 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000004067 70.0
HKD2_k127_3878290_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 320.0
HKD2_k127_3878290_3 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 316.0
HKD2_k127_3878290_4 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003646 277.0
HKD2_k127_3878290_7 membrane - - - 0.000000000000000000000000000000004902 141.0
HKD2_k127_3878290_8 Stigma-specific protein, Stig1 - - - 0.00000000000000000001163 103.0
HKD2_k127_3878290_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000001359 83.0
HKD2_k127_3883553_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 618.0
HKD2_k127_3883553_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 480.0
HKD2_k127_3883553_2 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 353.0
HKD2_k127_3883553_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001688 256.0
HKD2_k127_3883553_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000004762 245.0
HKD2_k127_3883553_5 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000001915 230.0
HKD2_k127_3883553_6 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000003532 223.0
HKD2_k127_3883553_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000001136 129.0
HKD2_k127_3883553_8 - - - - 0.0000000000000000000003476 111.0
HKD2_k127_3884075_0 secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000461 214.0
HKD2_k127_3884075_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000002762 195.0
HKD2_k127_3884075_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000001279 184.0
HKD2_k127_3884075_3 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000002945 142.0
HKD2_k127_3885752_0 Carboxyl transferase domain - - - 8.594e-285 891.0
HKD2_k127_3885752_1 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 302.0
HKD2_k127_3885752_2 Pfam:Kce - - - 0.00000000000000000000000000000000000000000000000000000000000000001078 226.0
HKD2_k127_3892910_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 605.0
HKD2_k127_3892910_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 567.0
HKD2_k127_3897957_0 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 342.0
HKD2_k127_3900758_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.266e-284 889.0
HKD2_k127_3903484_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1545.0
HKD2_k127_3903484_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 330.0
HKD2_k127_3903484_2 PA14 domain - - - 0.00000000000000000000000000000000000000000000000000000003252 199.0
HKD2_k127_3904026_0 Tim44 K15539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 357.0
HKD2_k127_3904026_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009611 340.0
HKD2_k127_3904026_2 alcohol dehydrogenase K00043 - 1.1.1.61 0.00000000000000000000325 105.0
HKD2_k127_3904026_3 Membrane K08988 - - 0.000000000000000000006966 106.0
HKD2_k127_3904810_0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000211 273.0
HKD2_k127_3904810_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000002061 243.0
HKD2_k127_3904810_2 Monogalactosyldiacylglycerol synthase K03429 - 2.4.1.315 0.0000000000000000000000000323 121.0
HKD2_k127_3904810_3 - - - - 0.000000000000433 83.0
HKD2_k127_3904810_4 serine-type peptidase activity - - - 0.000000000007042 79.0
HKD2_k127_3907157_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 371.0
HKD2_k127_3907157_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000003855 183.0
HKD2_k127_3907157_2 belongs to the thioredoxin family K00384,K02453,K11912,K20543 - 1.8.1.9,2.7.11.1 0.00000000000000000000000005344 116.0
HKD2_k127_3908261_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1314.0
HKD2_k127_39099_0 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004699 232.0
HKD2_k127_39099_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000007498 210.0
HKD2_k127_3910648_0 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 405.0
HKD2_k127_3910648_1 HB1, ASXL, restriction endonuclease HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 334.0
HKD2_k127_3910648_2 FHA domain - - - 0.00000000000000000000000000000000002705 138.0
HKD2_k127_3910648_3 COG0457 FOG TPR repeat - - - 0.000000000000001782 87.0
HKD2_k127_3911051_0 Mannosyl oligosaccharide glucosidase - - - 4.614e-251 786.0
HKD2_k127_3911051_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001405 254.0
HKD2_k127_3912499_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 548.0
HKD2_k127_3912499_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 537.0
HKD2_k127_3912499_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000001371 85.0
HKD2_k127_3912499_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000001285 79.0
HKD2_k127_3912499_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000001664 60.0
HKD2_k127_3913673_0 Elongator protein 3, MiaB family, Radical SAM K22226,K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 304.0
HKD2_k127_3913673_1 Crp-like helix-turn-helix domain - - - 0.000000000000000002238 87.0
HKD2_k127_3913673_2 Pfam Hemerythrin HHE - - - 0.0004875 51.0
HKD2_k127_3913940_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K15022 - 1.17.1.10 5.86e-274 854.0
HKD2_k127_3913940_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.117e-256 806.0
HKD2_k127_3913940_10 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000002526 198.0
HKD2_k127_3913940_11 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000001042 189.0
HKD2_k127_3913940_12 Methyltransferase type 11 - - - 0.0000000000000000000000000000000003445 140.0
HKD2_k127_3913940_13 - - - - 0.00000000000000000000000000009044 123.0
HKD2_k127_3913940_14 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000001286 126.0
HKD2_k127_3913940_2 HD domain - - - 9.632e-206 651.0
HKD2_k127_3913940_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 470.0
HKD2_k127_3913940_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 474.0
HKD2_k127_3913940_5 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 432.0
HKD2_k127_3913940_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 361.0
HKD2_k127_3913940_7 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 353.0
HKD2_k127_3913940_8 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000045 301.0
HKD2_k127_3913940_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003413 248.0
HKD2_k127_3919220_0 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001773 289.0
HKD2_k127_3919220_1 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000006768 151.0
HKD2_k127_3919220_2 Type II IV secretion system protein K02283,K03609 - - 0.000000000000000000000000000000001738 130.0
HKD2_k127_3919760_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000009373 260.0
HKD2_k127_3919760_1 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002141 254.0
HKD2_k127_3919760_2 Domain of unknown function (DUF4920) - - - 0.0000000000000244 78.0
HKD2_k127_3924441_0 response regulator K02481,K07713 - - 4.31e-215 679.0
HKD2_k127_3924441_1 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 313.0
HKD2_k127_3924441_2 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008447 282.0
HKD2_k127_3924441_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000002292 164.0
HKD2_k127_3924441_4 Histidine kinase-like ATPase domain K17752 - 2.7.11.1 0.0000000000000000000000000000000001061 140.0
HKD2_k127_3924441_5 DNA mismatch repair protein K07456 - - 0.000000000000000000000000000000004061 139.0
HKD2_k127_3924441_6 transporter antisigma-factor antagonist STAS K17762 - - 0.0000000000000000000000001075 119.0
HKD2_k127_3924441_7 Universal stress protein - - - 0.0000000000000000000000002145 113.0
HKD2_k127_3924441_8 anti-sigma regulatory factor K17752 - 2.7.11.1 0.00000000006122 73.0
HKD2_k127_3924441_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000199 63.0
HKD2_k127_393469_0 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 434.0
HKD2_k127_393469_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 331.0
HKD2_k127_393469_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 301.0
HKD2_k127_393469_3 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002221 247.0
HKD2_k127_393469_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0001209 45.0
HKD2_k127_393469_5 flagellar assembly protein FliH K02411 - - 0.0009146 51.0
HKD2_k127_3935085_0 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 364.0
HKD2_k127_3942511_0 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 405.0
HKD2_k127_3942511_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 422.0
HKD2_k127_3942511_2 Glutaredoxin - - - 0.0000000000000000000000000000002291 128.0
HKD2_k127_3948155_0 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 534.0
HKD2_k127_3948155_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 501.0
HKD2_k127_3948155_10 - - - - 0.00001203 57.0
HKD2_k127_3948155_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 370.0
HKD2_k127_3948155_3 Aldose 1-epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 337.0
HKD2_k127_3948155_4 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 - - - 0.000000000000000000000000000000000000000000000000000000000000001106 230.0
HKD2_k127_3948155_5 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000001711 201.0
HKD2_k127_3948155_6 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000001034 187.0
HKD2_k127_3948155_7 RF-1 domain K15034 - - 0.000000000000000000000000000000009863 139.0
HKD2_k127_3948155_8 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000008738 124.0
HKD2_k127_3948155_9 - - - - 0.0000000000000000000000000008334 116.0
HKD2_k127_3949325_0 Methionine synthase K00548 - 2.1.1.13 8.33e-316 980.0
HKD2_k127_3950573_0 Amidohydrolase family K01466 - 3.5.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 555.0
HKD2_k127_3950573_1 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 496.0
HKD2_k127_3950573_10 - - - - 0.00000000000000000000113 108.0
HKD2_k127_3950573_11 - - - - 0.0000000000000005013 90.0
HKD2_k127_3950573_12 PQQ-like domain K17713 - - 0.00000000001139 77.0
HKD2_k127_3950573_2 Belongs to the allantoicase family K01477 - 3.5.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 471.0
HKD2_k127_3950573_3 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 456.0
HKD2_k127_3950573_4 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 338.0
HKD2_k127_3950573_5 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001097 271.0
HKD2_k127_3950573_6 mevalonate kinase K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000005828 237.0
HKD2_k127_3950573_7 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000003827 233.0
HKD2_k127_3950573_8 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000003427 190.0
HKD2_k127_3950573_9 hydroxyisourate hydrolase activity K05689,K07127 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0016812,GO:0033971,GO:0034641,GO:0042579,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.2.17 0.000000000000000000000000001352 126.0
HKD2_k127_3956112_0 Cytochrome c554 and c-prime K01119 - 3.1.3.6,3.1.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 479.0
HKD2_k127_3956112_1 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 336.0
HKD2_k127_3956112_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001725 282.0
HKD2_k127_3956112_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004852 285.0
HKD2_k127_3956112_4 alpha beta K06889 - - 0.000000000000000000000000000000000000000001775 171.0
HKD2_k127_3956112_5 thiolester hydrolase activity - - - 0.0000000003996 74.0
HKD2_k127_3956976_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.842e-229 717.0
HKD2_k127_3956976_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 433.0
HKD2_k127_3956976_2 Glycosyl hydrolases family 43 - - - 0.0000000000000000134 84.0
HKD2_k127_3956976_3 Glycosyl hydrolases family 43 - - - 0.00000000000000001359 85.0
HKD2_k127_3958304_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 346.0
HKD2_k127_3958304_1 VIT family - - - 0.000000000000000000000000000000000000000000000000009095 187.0
HKD2_k127_3958304_2 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.00000004095 58.0
HKD2_k127_3958467_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 451.0
HKD2_k127_3958467_1 RmlD substrate binding domain K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 420.0
HKD2_k127_3958467_2 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000001974 199.0
HKD2_k127_3958467_3 - - - - 0.0000000000000000000000000000000000003639 144.0
HKD2_k127_3959021_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002788 273.0
HKD2_k127_3959021_1 PEGA domain - - - 0.00000000000000000000000000000000000000000000000000000000000004514 226.0
HKD2_k127_3959021_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000616 199.0
HKD2_k127_3962274_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 347.0
HKD2_k127_3962274_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000002725 155.0
HKD2_k127_3976918_0 Type III secretion protein K03230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 516.0
HKD2_k127_3976918_1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 492.0
HKD2_k127_3976918_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 340.0
HKD2_k127_3976918_3 PAP2 superfamily - - - 0.000000000000000000000000000000000000002373 159.0
HKD2_k127_3976918_4 S23 ribosomal protein - - - 0.000000000000000000000000000000001288 134.0
HKD2_k127_3976918_5 Universal stress protein - - - 0.000000000000000002827 95.0
HKD2_k127_3976918_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000002165 91.0
HKD2_k127_3978_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 510.0
HKD2_k127_3978_1 GMC oxidoreductase K03333 - 1.1.3.6 0.000000000000000000000000000000000000000000000000000000000001242 233.0
HKD2_k127_3978_2 Alanine racemase, N-terminal domain - - - 0.00000007043 56.0
HKD2_k127_3978_3 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00002305 53.0
HKD2_k127_3983573_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 524.0
HKD2_k127_3983573_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004118 269.0
HKD2_k127_3983573_2 FMN binding - - - 0.000000000000000000000000000000000002812 143.0
HKD2_k127_3983573_3 Flagellar basal body rod K01183,K02396 - 3.2.1.14 0.00000000000000000000000000000000004287 148.0
HKD2_k127_3992081_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 434.0
HKD2_k127_3992081_2 Tetratricopeptide repeats - - - 0.00009016 44.0
HKD2_k127_3994663_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000001358 174.0
HKD2_k127_3998254_0 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000002733 241.0
HKD2_k127_3998254_1 ABC-type Mn2 Zn2 transport systems permease components K09816 - - 0.00000000000000000000000000000000000000000000000006574 190.0
HKD2_k127_3998548_0 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000003875 148.0
HKD2_k127_3998548_1 AntiSigma factor - - - 0.0000000000000000000000000005509 127.0
HKD2_k127_3998548_2 amine dehydrogenase activity - - - 0.0000005469 62.0
HKD2_k127_3999368_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 1.129e-258 838.0
HKD2_k127_3999368_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 6.941e-251 802.0
HKD2_k127_3999368_10 carbon dioxide binding K04653,K04654 - - 0.00000000000000000000000000000003872 128.0
HKD2_k127_3999368_11 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.00000000000000000000000000000102 136.0
HKD2_k127_3999368_12 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000001524 119.0
HKD2_k127_3999368_14 PFAM regulatory protein LuxR - - - 0.00005738 49.0
HKD2_k127_3999368_2 Belongs to the HypD family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 505.0
HKD2_k127_3999368_3 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 450.0
HKD2_k127_3999368_4 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 434.0
HKD2_k127_3999368_5 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 400.0
HKD2_k127_3999368_6 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 312.0
HKD2_k127_3999368_7 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000001497 227.0
HKD2_k127_3999368_8 Domain of unknown function (DUF4405) - - - 0.000000000000000000000000000000000000000000009649 186.0
HKD2_k127_3999368_9 Enoyl-CoA hydratase carnithine racemase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000007005 171.0
HKD2_k127_4002477_0 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007001 280.0
HKD2_k127_4002477_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000003425 209.0
HKD2_k127_4002477_2 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000000000000001534 196.0
HKD2_k127_4002477_3 Metalloenzyme superfamily - - - 0.0000000000000000000000000000000000000000000000000559 202.0
HKD2_k127_4002477_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000002078 137.0
HKD2_k127_4003530_0 peptidyl-prolyl cis-trans isomerase activity K02597,K03769,K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000001367 224.0
HKD2_k127_4003530_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000005395 208.0
HKD2_k127_4003530_3 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000001664 103.0
HKD2_k127_4012894_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 495.0
HKD2_k127_4012894_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 440.0
HKD2_k127_4012894_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 390.0
HKD2_k127_4012894_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 333.0
HKD2_k127_4012894_4 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 341.0
HKD2_k127_4012894_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000008443 231.0
HKD2_k127_4012894_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000005184 192.0
HKD2_k127_4012894_7 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000006816 196.0
HKD2_k127_4012894_8 PEGA domain - - - 0.0000000000000000000000000000000000000000000006399 178.0
HKD2_k127_4012894_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000007434 137.0
HKD2_k127_4021625_0 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 326.0
HKD2_k127_4021625_1 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000003111 173.0
HKD2_k127_4021625_2 positive regulation of type IV pilus biogenesis K07343 - - 0.00000000000000006349 90.0
HKD2_k127_4021625_3 - K03561,K12287 - - 0.0002173 53.0
HKD2_k127_4029837_0 Family membership - - - 7.564e-207 689.0
HKD2_k127_4029837_1 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008447 361.0
HKD2_k127_4029837_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 329.0
HKD2_k127_4029837_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001026 257.0
HKD2_k127_4029837_4 Biotin-requiring enzyme - - - 0.00000000000000000000000000000000000000001708 160.0
HKD2_k127_4029837_5 Acyl-CoA dehydrogenase, middle domain K00232 - 1.3.3.6 0.0000000000000000000000000000000000000002924 169.0
HKD2_k127_4029837_6 Histidine kinase - - - 0.000000000000000000000000000002201 124.0
HKD2_k127_4029837_8 Collagenase K08303 - - 0.00000000001245 66.0
HKD2_k127_4029837_9 Bacterial virulence factor lipase N-terminal - - - 0.00001474 59.0
HKD2_k127_4042012_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 381.0
HKD2_k127_4042012_1 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 364.0
HKD2_k127_4042012_2 beta-lactamase activity K07126 - - 0.000000000000000000007636 108.0
HKD2_k127_4042012_3 ASPIC and UnbV - - - 0.000000000000001507 90.0
HKD2_k127_4051069_0 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 303.0
HKD2_k127_4051069_2 Transglycosylase K08309 - - 0.0000002186 59.0
HKD2_k127_4057637_0 SMART helicase c2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 475.0
HKD2_k127_4057637_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000944 268.0
HKD2_k127_4068296_0 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 8.29e-218 702.0
HKD2_k127_4068296_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 617.0
HKD2_k127_4068296_10 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.00005571 47.0
HKD2_k127_4068296_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 630.0
HKD2_k127_4068296_3 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 439.0
HKD2_k127_4068296_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 413.0
HKD2_k127_4068296_5 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 317.0
HKD2_k127_4068296_6 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007452 252.0
HKD2_k127_4068296_7 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000008475 144.0
HKD2_k127_4068296_8 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000006329 117.0
HKD2_k127_4068296_9 Phosphocarrier protein HPR K11189 - - 0.000000000000000000001771 109.0
HKD2_k127_4068883_0 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 410.0
HKD2_k127_4068883_1 Coenzyme A transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000004132 276.0
HKD2_k127_4068883_2 Uracil DNA glycosylase superfamily K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001192 256.0
HKD2_k127_4068883_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000004803 231.0
HKD2_k127_4068883_4 serine-type endopeptidase activity K07261 - - 0.000000000000000000000000000000000000000000000000000000001496 216.0
HKD2_k127_4068883_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000001913 137.0
HKD2_k127_4068883_6 Worm-specific repeat type 1 - - - 0.0000004113 61.0
HKD2_k127_4084704_0 Alpha-amylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 611.0
HKD2_k127_4084704_1 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 474.0
HKD2_k127_4084704_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 411.0
HKD2_k127_4084704_3 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 380.0
HKD2_k127_4084704_4 maltodextrin transmembrane transporter activity K02024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 356.0
HKD2_k127_4084704_5 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.000000000000000000000000000000000000001069 156.0
HKD2_k127_4084704_6 DUF218 domain - - - 0.0000000000000000000001352 115.0
HKD2_k127_4084704_7 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000007024 91.0
HKD2_k127_4084704_8 Psort location Cytoplasmic, score - - - 0.000002242 58.0
HKD2_k127_4085643_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 464.0
HKD2_k127_4085643_1 IgGFc binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 413.0
HKD2_k127_4085643_2 Family membership K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000004823 261.0
HKD2_k127_4085643_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K02487,K03832,K06596 - - 0.00000000188 63.0
HKD2_k127_4091245_0 VWA domain containing CoxE-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 442.0
HKD2_k127_4091245_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 343.0
HKD2_k127_4091245_10 Protein of unknown function (DUF3455) - - - 0.000000000000000001009 96.0
HKD2_k127_4091245_11 Domain of unknown function (DUF4382) - - - 0.000000000000000003405 94.0
HKD2_k127_4091245_12 Domain of unknown function (DUF4870) K09940 - - 0.000004442 53.0
HKD2_k127_4091245_13 PFAM WD domain, G-beta repeat - - - 0.0001502 55.0
HKD2_k127_4091245_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 318.0
HKD2_k127_4091245_3 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 317.0
HKD2_k127_4091245_4 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000327 238.0
HKD2_k127_4091245_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000285 182.0
HKD2_k127_4091245_7 Protein of unknown function (DUF1109) - - - 0.0000000000000000000000000000000000000001121 158.0
HKD2_k127_4091245_8 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000001414 132.0
HKD2_k127_4091245_9 - - - - 0.00000000000000000000000009131 122.0
HKD2_k127_4098072_0 Belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 331.0
HKD2_k127_4098072_1 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000000001761 207.0
HKD2_k127_4098072_2 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.00000000000000000000000000000000002298 156.0
HKD2_k127_4098072_3 FHA domain - - - 0.00000000000000000000000000000000004132 153.0
HKD2_k127_4098072_4 NACHT domain - - - 0.0000000000000000000000000000001687 144.0
HKD2_k127_4098072_5 - - - - 0.00000000001493 72.0
HKD2_k127_4098072_6 YCII-related domain - - - 0.0000006042 60.0
HKD2_k127_4098072_7 Dickkopf N-terminal cysteine-rich region - - - 0.0003668 48.0
HKD2_k127_4099091_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 315.0
HKD2_k127_4099091_1 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000009081 50.0
HKD2_k127_4110937_0 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002148 296.0
HKD2_k127_4110937_1 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000002884 188.0
HKD2_k127_4110937_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000003419 171.0
HKD2_k127_4110937_3 signal sequence binding K07152 - - 0.000000000000000000000000000000003512 137.0
HKD2_k127_4110937_4 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000007337 87.0
HKD2_k127_4114941_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001124 265.0
HKD2_k127_4114941_1 COG2755 Lysophospholipase L1 and related esterases - - - 0.0000000000000000000000000000000000000000000001501 185.0
HKD2_k127_4114941_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000005302 159.0
HKD2_k127_4114941_4 Alpha beta hydrolase - - - 0.000000000000000004787 96.0
HKD2_k127_4114973_0 Family membership - - - 0.0000000000000000000000000000000000000000000000000000000001473 220.0
HKD2_k127_4114973_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000003013 156.0
HKD2_k127_4114973_3 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.000001497 53.0
HKD2_k127_4114973_5 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0001668 44.0
HKD2_k127_4117762_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 2.842e-235 754.0
HKD2_k127_4117762_1 Sugar ABC transporter permease K10109,K15770,K15771 - - 1.04e-227 728.0
HKD2_k127_4117762_10 PFAM Glycosyltransferase family 28 C-terminal domain K03429 - 2.4.1.315 0.000000000000000000000000000000000003906 152.0
HKD2_k127_4117762_11 Binding-protein-dependent transport system inner membrane component K10110,K15772 - - 0.00000000000005248 78.0
HKD2_k127_4117762_12 serine-type peptidase activity - - - 0.0000000000002428 83.0
HKD2_k127_4117762_13 - - - - 0.0002625 53.0
HKD2_k127_4117762_2 Belongs to the ABC transporter superfamily K05816,K10112 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 437.0
HKD2_k127_4117762_3 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 403.0
HKD2_k127_4117762_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 362.0
HKD2_k127_4117762_5 Binding-protein-dependent transport system inner membrane component K10110,K15772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 351.0
HKD2_k127_4117762_6 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003791 273.0
HKD2_k127_4117762_7 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000000000000000000000000000000000000000000000000000000003664 220.0
HKD2_k127_4117762_9 Type II IV secretion system protein K02283,K03609 - - 0.00000000000000000000000000000000000000000005099 171.0
HKD2_k127_4120280_1 Bacterial virulence factor lipase N-terminal - - - 0.0000000000000000513 96.0
HKD2_k127_4128972_0 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 454.0
HKD2_k127_4128972_1 Acyl-protein synthetase, LuxE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 305.0
HKD2_k127_4128972_2 gluconolactonase activity - - - 0.0002257 54.0
HKD2_k127_4131292_0 Beta-eliminating lyase K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 490.0
HKD2_k127_4131292_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 435.0
HKD2_k127_4131292_2 Belongs to the beta-ketoacyl-ACP synthases family K00646 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 347.0
HKD2_k127_4131292_3 malonyl CoA-acyl carrier protein transacylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003821 263.0
HKD2_k127_4131292_4 FabA-like domain K02372 - 4.2.1.59 0.00000000000000000000000000000000000003087 153.0
HKD2_k127_4131292_5 Crp-like helix-turn-helix domain - - - 0.000000000000000000000001058 111.0
HKD2_k127_4156165_0 IgGFc binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 430.0
HKD2_k127_4159186_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 546.0
HKD2_k127_4159186_1 lipid kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001482 239.0
HKD2_k127_4159186_2 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000001352 213.0
HKD2_k127_4159186_4 ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD K16013,K16014 - - 0.0000000000000000000000000001626 132.0
HKD2_k127_4174864_0 Oxidoreductase NAD-binding domain K00380 - 1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 304.0
HKD2_k127_417596_0 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 529.0
HKD2_k127_41854_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 601.0
HKD2_k127_41854_1 PFAM alanine dehydrogenase PNT domain protein K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 551.0
HKD2_k127_41854_2 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 313.0
HKD2_k127_41854_3 Highly conserved protein containing a thioredoxin domain - - - 0.0000000000000000000007213 111.0
HKD2_k127_4193810_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 436.0
HKD2_k127_4193810_2 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000002515 219.0
HKD2_k127_4193810_3 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000003772 209.0
HKD2_k127_4193810_4 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000001731 201.0
HKD2_k127_4193810_5 Uncharacterized protein conserved in bacteria (DUF2171) - - - 0.0000000000000000000000008436 106.0
HKD2_k127_4193810_6 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000009095 108.0
HKD2_k127_4193810_7 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000006155 51.0
HKD2_k127_4193810_8 Biopolymer transport protein ExbD/TolR - - - 0.00008909 56.0
HKD2_k127_4206213_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 388.0
HKD2_k127_4206213_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000001146 201.0
HKD2_k127_4206624_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 1.064e-243 782.0
HKD2_k127_4206624_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 553.0
HKD2_k127_4206624_2 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 447.0
HKD2_k127_4206624_3 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 391.0
HKD2_k127_4206624_4 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 362.0
HKD2_k127_4206624_5 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 349.0
HKD2_k127_4206624_6 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000005896 170.0
HKD2_k127_4206624_7 twitching motility protein K02669 - - 0.0000000000000000000000000003745 115.0
HKD2_k127_4206624_8 DGQHR domain - - - 0.0008092 49.0
HKD2_k127_421015_0 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000001056 239.0
HKD2_k127_4217765_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 338.0
HKD2_k127_4217765_1 GAF domain - - - 0.00000000000000000000000000000000000000000000000000001232 206.0
HKD2_k127_4217765_2 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000003659 152.0
HKD2_k127_4222121_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 391.0
HKD2_k127_4222121_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000005022 152.0
HKD2_k127_422232_0 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 511.0
HKD2_k127_422232_1 Flagellar Motor Protein K11892 - - 0.000000000000000000000000000000000000000000000000000000000000000000003604 243.0
HKD2_k127_422232_10 - - - - 0.0000001654 63.0
HKD2_k127_422232_11 4Fe-4S binding domain - - - 0.00008055 46.0
HKD2_k127_422232_2 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000007418 186.0
HKD2_k127_422232_3 - - - - 0.0000000000000000000000000000000000000000008296 169.0
HKD2_k127_422232_4 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000003253 156.0
HKD2_k127_422232_5 - - - - 0.000000000000000000000000001661 120.0
HKD2_k127_422232_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000007358 126.0
HKD2_k127_422232_7 meiotic cell cycle K15216,K16474,K20285,K22207 GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0006355,GO:0008150,GO:0009653,GO:0009889,GO:0010468,GO:0010556,GO:0012505,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048856,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 4.4.1.28 0.0000000000000000002809 100.0
HKD2_k127_422232_9 - - - - 0.000000000000004766 86.0
HKD2_k127_4228112_0 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000008837 188.0
HKD2_k127_4228112_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000004859 186.0
HKD2_k127_4228112_2 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000006339 106.0
HKD2_k127_4246828_0 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 479.0
HKD2_k127_4246828_1 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 417.0
HKD2_k127_4246828_2 IgGFc binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 406.0
HKD2_k127_4246828_3 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009269 292.0
HKD2_k127_4246828_4 Uncharacterised conserved protein (DUF2156) - - - 0.000000000000000000000000000000000000000000000000000000000000001492 231.0
HKD2_k127_4246828_5 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000000000000000003143 156.0
HKD2_k127_4246828_6 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000002931 118.0
HKD2_k127_4246828_7 Chlorophyllase - - - 0.00000000000001603 84.0
HKD2_k127_4246828_9 CBS domain K04767 - - 0.00000000007916 73.0
HKD2_k127_424979_0 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 308.0
HKD2_k127_424979_1 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001156 254.0
HKD2_k127_424979_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000003395 225.0
HKD2_k127_424979_3 Methyltransferase domain K15256 - - 0.0000000000000000000000000000000000000000000003984 174.0
HKD2_k127_424979_4 YXWGXW repeat (2 copies) - - - 0.0000000001848 72.0
HKD2_k127_4250279_0 Tetratricopeptide repeat - - - 0.0 1235.0
HKD2_k127_4250279_1 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001287 269.0
HKD2_k127_4250279_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000345 202.0
HKD2_k127_4250279_3 Protein of unknown function, DUF255 - - - 0.00000000000000000000000000000000001256 138.0
HKD2_k127_4250279_4 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000004629 120.0
HKD2_k127_4255368_0 Bacterial regulatory protein, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 366.0
HKD2_k127_4255368_1 Histidine kinase K02668 - 2.7.13.3 0.000000000000000000000000002758 123.0
HKD2_k127_4256352_0 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006536 284.0
HKD2_k127_4256352_1 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000004662 164.0
HKD2_k127_4256352_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000001089 130.0
HKD2_k127_4277608_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 395.0
HKD2_k127_4277608_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 336.0
HKD2_k127_4277608_3 Histidine kinase - - - 0.00000000000000000000000000000000000000008905 157.0
HKD2_k127_4277608_4 HEAT repeats - - - 0.0000000000000000000000000000000000004681 151.0
HKD2_k127_4282449_0 acid phosphatase activity K22390 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001597 274.0
HKD2_k127_4282449_1 acid phosphatase activity K22390 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001632 268.0
HKD2_k127_4283023_0 PFAM monooxygenase FAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 473.0
HKD2_k127_4283023_1 - - - - 0.000000000000000000000000000000000000000000000001922 181.0
HKD2_k127_4284873_0 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 372.0
HKD2_k127_4284873_1 COG1045 Serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 298.0
HKD2_k127_4284873_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01991,K02005,K06147,K12542,K16552,K19291 - 2.4.1.33 0.000000000000008353 87.0
HKD2_k127_4298050_0 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 3.547e-248 781.0
HKD2_k127_4298050_1 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412,K03224 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 457.0
HKD2_k127_4298050_10 peptidyl-tyrosine sulfation - - - 0.0000000007875 72.0
HKD2_k127_4298050_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 391.0
HKD2_k127_4298050_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 296.0
HKD2_k127_4298050_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003058 273.0
HKD2_k127_4298050_5 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.000000000000000000000000000000000000000000000004114 181.0
HKD2_k127_4298050_6 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000000000000000000001686 160.0
HKD2_k127_4298050_7 High-affinity nickel-transport protein K07241 - - 0.00000000000000000000000000000000000002857 150.0
HKD2_k127_4298050_8 domain protein - - - 0.00000000001152 78.0
HKD2_k127_4298050_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.0000000000199 73.0
HKD2_k127_4299450_0 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 338.0
HKD2_k127_4299450_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000003368 252.0
HKD2_k127_4299450_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000003072 134.0
HKD2_k127_4299450_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000002638 109.0
HKD2_k127_4303545_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 445.0
HKD2_k127_4303545_1 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 374.0
HKD2_k127_430764_0 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 483.0
HKD2_k127_430764_1 Uncharacterized conserved protein (DUF2293) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 305.0
HKD2_k127_430764_2 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000496 217.0
HKD2_k127_430764_3 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000006752 236.0
HKD2_k127_430764_4 Alanine racemase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000001976 217.0
HKD2_k127_430764_5 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000001947 159.0
HKD2_k127_430764_6 membrane organization K07126,K07277 - - 0.0000000000000000000295 103.0
HKD2_k127_430764_7 - - - - 0.000000000000009148 87.0
HKD2_k127_430764_8 exo-alpha-(2->6)-sialidase activity - - - 0.0005895 53.0
HKD2_k127_4308632_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 326.0
HKD2_k127_4308632_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000001912 195.0
HKD2_k127_4308632_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000015 121.0
HKD2_k127_4308632_6 protein transport across the cell outer membrane - - - 0.0000000000000004545 90.0
HKD2_k127_4308632_7 domain, Protein - - - 0.000000000000006421 78.0
HKD2_k127_4321330_0 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 461.0
HKD2_k127_4321330_1 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 372.0
HKD2_k127_4321330_2 Carboxylesterase family - - - 0.0000000000000000002261 93.0
HKD2_k127_4321330_3 ABC-type Mn2 Zn2 transport systems permease components - - - 0.00000000000000003564 89.0
HKD2_k127_4345784_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 344.0
HKD2_k127_4345784_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 292.0
HKD2_k127_4345784_2 Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006599 265.0
HKD2_k127_4345784_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000008674 151.0
HKD2_k127_4345784_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000002046 109.0
HKD2_k127_434917_0 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 315.0
HKD2_k127_434917_1 - - - - 0.000000000000000000000000000000000000000000000000000000001042 220.0
HKD2_k127_434917_2 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000001979 114.0
HKD2_k127_4371139_0 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 546.0
HKD2_k127_4371139_1 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 424.0
HKD2_k127_4371139_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000002535 239.0
HKD2_k127_4371139_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000157 214.0
HKD2_k127_4371139_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000001266 109.0
HKD2_k127_4371139_5 transcriptional regulator K07722 - - 0.00000000000000000000000104 122.0
HKD2_k127_4371139_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000001101 108.0
HKD2_k127_4371139_7 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001597 72.0
HKD2_k127_4376055_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 378.0
HKD2_k127_4376055_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005531 260.0
HKD2_k127_4376055_3 Lysin motif K08307 - - 0.0000000000000000000009599 100.0
HKD2_k127_4380029_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 4.273e-218 696.0
HKD2_k127_4380029_1 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009113 248.0
HKD2_k127_4380029_2 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.00000000000000000000000000000000000000000000000003261 183.0
HKD2_k127_4401291_0 WD40-like Beta Propeller Repeat - - - 1.804e-252 812.0
HKD2_k127_4401291_1 Cell division protein FtsI penicillin-binding protein 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 330.0
HKD2_k127_4401291_2 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 337.0
HKD2_k127_4401291_3 Thymidine kinase K00857 - 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000036 222.0
HKD2_k127_4401291_5 - - - - 0.00000000000000000000001427 113.0
HKD2_k127_4401291_6 Rhodanese Homology Domain - - - 0.000000000000000000006441 97.0
HKD2_k127_4401291_8 Peptidase family S51 - - - 0.00000000002366 77.0
HKD2_k127_4401912_0 protein trimerization K06894,K07114 - - 0.0000000000000000000000000000001051 138.0
HKD2_k127_4405341_0 TIGRFAM glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 3.398e-233 736.0
HKD2_k127_4405341_1 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 364.0
HKD2_k127_4405341_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003453 246.0
HKD2_k127_4405510_0 Family membership - - - 4.008e-288 928.0
HKD2_k127_4405510_1 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 587.0
HKD2_k127_4405510_2 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 313.0
HKD2_k127_4405510_3 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000000001986 233.0
HKD2_k127_4405510_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000008595 222.0
HKD2_k127_4405510_5 NAD+ diphosphatase activity K03426,K20449 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0035529,GO:0043167,GO:0043169,GO:0046872,GO:0046914 1.3.7.1,3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000188 224.0
HKD2_k127_4405510_6 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000013 132.0
HKD2_k127_4405510_7 SCO1/SenC K07152 - - 0.0000000000000000000000000000001519 139.0
HKD2_k127_4405510_8 - - - - 0.0000000000000000000001066 100.0
HKD2_k127_4405510_9 Transcription factor zinc-finger - - - 0.0000000000000000000006573 105.0
HKD2_k127_4410123_0 AMP-binding enzyme C-terminal domain K18660,K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 477.0
HKD2_k127_4410123_1 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 328.0
HKD2_k127_4410123_10 Periplasmic protein thiol disulfide oxidoreductase, DsbE subfamily - - - 0.00001913 54.0
HKD2_k127_4410123_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003875 276.0
HKD2_k127_4410123_3 Iron-containing redox enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000618 269.0
HKD2_k127_4410123_6 - - - - 0.00000000000000000000000005219 107.0
HKD2_k127_4410123_7 Trypsin-like serine protease - - - 0.0000000003474 73.0
HKD2_k127_4410123_8 - - - - 0.0000000007886 59.0
HKD2_k127_4410123_9 Cro/C1-type HTH DNA-binding domain - - - 0.00000002012 59.0
HKD2_k127_4415255_0 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 457.0
HKD2_k127_4415255_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000625 273.0
HKD2_k127_4415255_2 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000035 156.0
HKD2_k127_4420960_0 Amidohydrolase family - - - 1.521e-260 818.0
HKD2_k127_4420960_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - 7.778e-246 776.0
HKD2_k127_4420960_10 Protein of unknown function (DUF465) K09794 - - 0.00000000000009661 76.0
HKD2_k127_4420960_2 Belongs to the amidase family K19176 - 3.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 505.0
HKD2_k127_4420960_3 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 318.0
HKD2_k127_4420960_4 Zinc finger domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 299.0
HKD2_k127_4420960_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000177 265.0
HKD2_k127_4420960_6 4Fe-4S single cluster domain K06139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001179 264.0
HKD2_k127_4420960_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000004989 141.0
HKD2_k127_4420960_8 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000003298 124.0
HKD2_k127_4420960_9 Phosphoesterase family K01114 - 3.1.4.3 0.0000000000000000000000000001718 132.0
HKD2_k127_4420965_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000004542 248.0
HKD2_k127_4420965_1 - - - - 0.0000000000001987 82.0
HKD2_k127_4428857_0 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 479.0
HKD2_k127_4428857_1 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K06147,K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 475.0
HKD2_k127_4428857_2 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000003091 216.0
HKD2_k127_4428857_3 transferase activity, transferring glycosyl groups K16153 - 2.4.1.1,2.4.1.11 0.00000000006939 71.0
HKD2_k127_4428857_4 Colicin V production protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944 - 0.000001918 60.0
HKD2_k127_4428857_5 exo-alpha-(2->6)-sialidase activity - - - 0.000007485 59.0
HKD2_k127_4428857_6 Cupin - - - 0.0006041 51.0
HKD2_k127_4441447_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 444.0
HKD2_k127_4441447_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 383.0
HKD2_k127_4441447_2 Transcriptional regulator K15973 - - 0.0000000000000000000000000000000000004904 145.0
HKD2_k127_4441447_3 - - - - 0.0000000000000000000000000000000001647 138.0
HKD2_k127_4449934_0 Belongs to the transketolase family K00615 - 2.2.1.1 2.3e-311 969.0
HKD2_k127_4449934_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 437.0
HKD2_k127_4449934_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000008238 141.0
HKD2_k127_4449934_3 amine dehydrogenase activity - - - 0.000442 53.0
HKD2_k127_4473975_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000376 219.0
HKD2_k127_4473975_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000001874 156.0
HKD2_k127_4473975_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000002213 126.0
HKD2_k127_4474514_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000004316 60.0
HKD2_k127_4476595_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 479.0
HKD2_k127_4476595_1 Tetratricopeptide repeat - - - 0.00000000000002594 87.0
HKD2_k127_4490844_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.615e-212 666.0
HKD2_k127_4490844_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 485.0
HKD2_k127_4490844_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 425.0
HKD2_k127_4490844_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000004202 203.0
HKD2_k127_450407_1 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000007156 242.0
HKD2_k127_450407_2 zinc-ribbon domain - - - 0.0000000000005495 71.0
HKD2_k127_4504375_0 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 401.0
HKD2_k127_4504375_1 Ubiquinol-cytochrome C reductase - - - 0.0000000000000000000000000000000000000000000003669 175.0
HKD2_k127_4504375_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000034 151.0
HKD2_k127_4504375_4 Leucine-rich repeat (LRR) protein K13730 - - 0.000000000001693 72.0
HKD2_k127_4541563_0 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 412.0
HKD2_k127_4541563_1 GMP synthase (glutamine-hydrolyzing) activity - - - 0.000000000000000000000000000000000000000000000000000000000000008392 221.0
HKD2_k127_4541563_2 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000114 191.0
HKD2_k127_4546785_0 beta-glucosidase K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 456.0
HKD2_k127_4546785_1 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009812 277.0
HKD2_k127_4570402_0 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 581.0
HKD2_k127_4570402_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001637 272.0
HKD2_k127_4570402_2 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000001487 249.0
HKD2_k127_4598165_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 420.0
HKD2_k127_4598165_1 two component, sigma54 specific, transcriptional regulator, Fis family K10941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 353.0
HKD2_k127_4598165_10 cell envelope organization K05807,K08309 - - 0.00000000000000000001886 103.0
HKD2_k127_4598165_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 301.0
HKD2_k127_4598165_3 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006607 286.0
HKD2_k127_4598165_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004873 263.0
HKD2_k127_4598165_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000007869 193.0
HKD2_k127_4598165_6 Glycosyl hydrolases family 25 K07273 - - 0.000000000000000000000000000000000000000000007322 181.0
HKD2_k127_4598165_7 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000006114 166.0
HKD2_k127_4598165_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000001176 114.0
HKD2_k127_4598165_9 Belongs to the ompA family - - - 0.0000000000000000000001064 104.0
HKD2_k127_4621397_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 492.0
HKD2_k127_4621397_1 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008798 368.0
HKD2_k127_4621397_3 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000001848 149.0
HKD2_k127_4621397_4 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.0000000000000000000000000000001388 143.0
HKD2_k127_4621397_5 COG3209 Rhs family protein - - - 0.000000000000000000000000009987 128.0
HKD2_k127_4621397_6 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000003659 107.0
HKD2_k127_4621397_7 Belongs to the UPF0312 family - - - 0.000000005028 66.0
HKD2_k127_463412_0 ABC transporter K06020 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 607.0
HKD2_k127_463412_1 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001295 273.0
HKD2_k127_463412_2 Putative diguanylate phosphodiesterase - - - 0.0000000001076 74.0
HKD2_k127_463412_3 helix_turn_helix, Lux Regulon - - - 0.0000001794 61.0
HKD2_k127_4679759_0 UPF0313 protein - - - 9.743e-287 899.0
HKD2_k127_4679759_1 sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 466.0
HKD2_k127_4679759_10 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000001935 177.0
HKD2_k127_4679759_11 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000004964 176.0
HKD2_k127_4679759_12 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000008038 164.0
HKD2_k127_4679759_13 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000001333 181.0
HKD2_k127_4679759_14 ABC transporter, ATP-binding protein - - - 0.00000000000000000000000000000000000003228 145.0
HKD2_k127_4679759_15 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000000000000000000004101 155.0
HKD2_k127_4679759_16 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000001217 151.0
HKD2_k127_4679759_17 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000001819 143.0
HKD2_k127_4679759_18 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000000000588 119.0
HKD2_k127_4679759_19 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000001119 114.0
HKD2_k127_4679759_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 383.0
HKD2_k127_4679759_23 Domain of unknown function (DUF4266) - - - 0.000000007964 66.0
HKD2_k127_4679759_3 PFAM cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 343.0
HKD2_k127_4679759_4 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 294.0
HKD2_k127_4679759_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007212 299.0
HKD2_k127_4679759_6 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002745 257.0
HKD2_k127_4679759_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000001967 220.0
HKD2_k127_4679759_8 alpha beta - - - 0.000000000000000000000000000000000000000000000000000002968 203.0
HKD2_k127_4679759_9 - - - - 0.0000000000000000000000000000000000000000000000001218 189.0
HKD2_k127_4695922_0 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000004474 219.0
HKD2_k127_4722906_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 376.0
HKD2_k127_4722906_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000045 185.0
HKD2_k127_4722906_2 Protein phosphatase 2A homologues, catalytic domain. - - - 0.0000000000000000000000000000000000000009155 151.0
HKD2_k127_4722906_3 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000002863 85.0
HKD2_k127_4722906_4 - - - - 0.000000000004019 76.0
HKD2_k127_4774471_0 WD domain- G-beta repeat PBS lyase HEAT-like K03497 - - 0.0 1632.0
HKD2_k127_4774471_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA - - - 5.359e-283 899.0
HKD2_k127_4774471_2 Proton-conducting membrane transporter K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 528.0
HKD2_k127_4774471_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 325.0
HKD2_k127_4774471_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343,K05573 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 335.0
HKD2_k127_4774471_5 Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000003289 241.0
HKD2_k127_4774471_6 Rubrerythrin - - - 0.0000000000000000000000000000000000000000001392 165.0
HKD2_k127_4774471_7 PAS domain - - - 0.000000000000000000000000000000005829 144.0
HKD2_k127_4774471_8 Proposed nucleic acid binding domain - - - 0.000000000000000000000000002951 122.0
HKD2_k127_4774471_9 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.00000000000000001278 96.0
HKD2_k127_477711_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 535.0
HKD2_k127_477711_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001383 279.0
HKD2_k127_477711_2 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - - 0.00000000000000000000000000000000000000000000007997 173.0
HKD2_k127_477711_3 k transport K10716 - - 0.000000000000000000000000000000000009683 146.0
HKD2_k127_477711_4 YXWGXW repeat (2 copies) - - - 0.000000000000000000000000008653 128.0
HKD2_k127_4784271_0 Belongs to the glycosyl hydrolase 31 family K01811,K15922 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016798,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777,GO:1990929 3.2.1.177,3.2.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 389.0
HKD2_k127_4784271_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000001762 171.0
HKD2_k127_4789674_0 heat shock protein 70 K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 582.0
HKD2_k127_4789674_1 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 341.0
HKD2_k127_4789674_2 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001326 261.0
HKD2_k127_4789674_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002418 249.0
HKD2_k127_4789674_4 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001801 251.0
HKD2_k127_4789674_5 phospholipase C K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000003835 237.0
HKD2_k127_4801266_0 Found in ATP-dependent protease La (LON) K01338 - 3.4.21.53 1.044e-227 732.0
HKD2_k127_4801266_1 Family membership - - - 6.021e-218 722.0
HKD2_k127_4801266_2 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 375.0
HKD2_k127_4801266_3 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 361.0
HKD2_k127_4801266_4 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000006457 237.0
HKD2_k127_4801266_5 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000002187 236.0
HKD2_k127_4801266_6 S-acyltransferase activity K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000004977 183.0
HKD2_k127_4801266_7 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000000000000212 151.0
HKD2_k127_4801266_8 PFAM Uncharacterised ACR, COG1259 K08999 - - 0.0000000000000001907 87.0
HKD2_k127_4801266_9 Neurotransmitter-gated ion-channel ligand binding domain - - - 0.00000000000006718 83.0
HKD2_k127_482809_0 helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 520.0
HKD2_k127_482809_1 Secretory protein of YscJ/FliF family K03222 - - 0.00000000000000000000000000006244 125.0
HKD2_k127_482809_2 ABC transporter K02065 - - 0.00000003088 57.0
HKD2_k127_48426_0 all-trans-retinol 13,14-reductase activity K09516,K09835 - 1.3.99.23,5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 343.0
HKD2_k127_48426_1 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002076 289.0
HKD2_k127_48426_3 acid phosphatase activity K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000009092 181.0
HKD2_k127_48426_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000004047 156.0
HKD2_k127_48426_5 glutathionylspermidine amidase activity K01460 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008884,GO:0008885,GO:0016787,GO:0016810,GO:0016811,GO:0016874,GO:0016879,GO:0016880,GO:0044424,GO:0044444,GO:0044464 3.5.1.78,6.3.1.8 0.0000000000000000000000000006737 132.0
HKD2_k127_48426_7 Glycosyl hydrolases family 18 - - - 0.000000000001455 81.0
HKD2_k127_485019_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000226 240.0
HKD2_k127_4877749_0 von Willebrand factor type A domain - - - 0.0 1086.0
HKD2_k127_4877749_1 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 616.0
HKD2_k127_4877749_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 405.0
HKD2_k127_4877749_3 Dienelactone hydrolase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 393.0
HKD2_k127_4877749_4 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 365.0
HKD2_k127_4877749_5 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 346.0
HKD2_k127_4877749_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 322.0
HKD2_k127_4877749_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 313.0
HKD2_k127_4877749_8 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000000000000000000006666 204.0
HKD2_k127_4877749_9 - - - - 0.0000000000005881 81.0
HKD2_k127_488631_0 AMP-binding enzyme - - - 5.085e-235 740.0
HKD2_k127_488631_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 503.0
HKD2_k127_488631_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 499.0
HKD2_k127_488631_3 PFAM PEGA domain K02035 - - 0.000007941 57.0
HKD2_k127_4915470_0 Amidohydrolase family - - - 1.024e-234 739.0
HKD2_k127_4915470_1 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000001412 188.0
HKD2_k127_4915470_2 iron ion binding - - - 0.0000000000000000000000000000000003076 139.0
HKD2_k127_4915470_3 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000224 115.0
HKD2_k127_4915470_4 Pentapeptide repeat protein - - - 0.000000000000000000008929 101.0
HKD2_k127_4922377_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 442.0
HKD2_k127_4922377_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 415.0
HKD2_k127_4922377_2 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 302.0
HKD2_k127_4922377_3 peptidyl-tyrosine sulfation - - - 0.0004634 50.0
HKD2_k127_495106_0 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 345.0
HKD2_k127_495106_1 tryptophan 2,3-dioxygenase activity K00453,K03392 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 0.00000000000000000000000000000000000000000000000001183 201.0
HKD2_k127_5018675_0 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 338.0
HKD2_k127_5018675_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000004101 259.0
HKD2_k127_5018675_2 Penicillin-insensitive murein endopeptidase K07261 - - 0.000000000000000000000000000000000000000000000000000000000000000000001802 246.0
HKD2_k127_5018675_4 Domain of unknown function (DUF4412) - - - 0.00000007811 63.0
HKD2_k127_5018675_5 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0001872 49.0
HKD2_k127_502897_0 DNA helicase K03656,K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 636.0
HKD2_k127_502897_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 441.0
HKD2_k127_502897_2 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 342.0
HKD2_k127_502897_3 Protein of unknown function (DUF1592) - - - 0.0000000000000000000000000000000000000000000000000000001306 205.0
HKD2_k127_502897_4 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000004008 195.0
HKD2_k127_502897_7 - - - - 0.0000000000000000000000000000000000000000000003071 178.0
HKD2_k127_502897_9 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.00000000001609 75.0
HKD2_k127_503304_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 4.51e-231 734.0
HKD2_k127_503304_1 Class-II DAHP synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 433.0
HKD2_k127_503304_2 Transglycosylase K08309 - - 0.00000000000000000000000000000000000000000000000000000000000008623 216.0
HKD2_k127_503304_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000006592 147.0
HKD2_k127_503304_4 - - - - 0.0000000000417 77.0
HKD2_k127_503304_6 Tetratricopeptide repeat - - - 0.0004714 52.0
HKD2_k127_50404_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 394.0
HKD2_k127_50404_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 370.0
HKD2_k127_50404_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 299.0
HKD2_k127_50404_3 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001709 216.0
HKD2_k127_50404_4 Putative zinc-finger - - - 0.0000000000000000000000000000000005269 147.0
HKD2_k127_50404_5 ABC-type multidrug transport system ATPase component - - - 0.0000000000005361 82.0
HKD2_k127_50404_6 PHB/PHA accumulation regulator DNA-binding domain - - - 0.000392 44.0
HKD2_k127_5071402_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002969 267.0
HKD2_k127_5071402_1 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000003987 159.0
HKD2_k127_5071402_2 Rieske 2Fe-2S - - - 0.00000000000001019 84.0
HKD2_k127_5083354_0 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 323.0
HKD2_k127_5083354_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000006912 179.0
HKD2_k127_5083354_2 - - - - 0.00000000000000000000000000005999 135.0
HKD2_k127_5083354_3 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 0.00000000000000000000003174 106.0
HKD2_k127_5083354_4 energy transducer activity K03832,K07277 - - 0.000000000000000001854 99.0
HKD2_k127_5083354_5 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000006805 98.0
HKD2_k127_5083354_6 Tetratricopeptide repeat - - - 0.00000000000000006121 95.0
HKD2_k127_5089160_0 Tetratricopeptide repeat - - - 8.959e-320 1008.0
HKD2_k127_509374_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 467.0
HKD2_k127_5103734_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 489.0
HKD2_k127_5103734_1 Psort location Cytoplasmic, score K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 361.0
HKD2_k127_5103734_2 Beta-galactosidase - - - 0.000000000000000000000000000000000000000001372 173.0
HKD2_k127_5103734_3 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000001437 159.0
HKD2_k127_5103734_4 PFAM glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000002438 136.0
HKD2_k127_5103734_5 PFAM Bacterial transferase hexapeptide (three repeats) - - - 0.0000000000000000000001039 107.0
HKD2_k127_5103734_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000001118 78.0
HKD2_k127_5103734_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000003162 65.0
HKD2_k127_5113124_0 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 439.0
HKD2_k127_5116243_0 AAA domain (dynein-related subfamily) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 541.0
HKD2_k127_5116243_1 - - - - 0.0000000000000000000002867 99.0
HKD2_k127_5116243_2 Glycoprotease family K01409,K14742 - 2.3.1.234 0.000000000000005401 88.0
HKD2_k127_5116243_3 - - - - 0.0000004185 61.0
HKD2_k127_5124560_0 Pfam:Kce - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 344.0
HKD2_k127_5124560_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 351.0
HKD2_k127_5124560_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000005729 185.0
HKD2_k127_5127344_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 3.954e-254 797.0
HKD2_k127_5127344_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 1.177e-203 657.0
HKD2_k127_5127344_10 phospholipase C K21302 - 3.1.3.64 0.00000000000000000000000000000000000000375 157.0
HKD2_k127_5127344_12 Flavodoxin - - - 0.00000000000000000005264 105.0
HKD2_k127_5127344_13 ATP ADP translocase K03301 - - 0.000000000000000001356 100.0
HKD2_k127_5127344_14 Cbs domain - - - 0.00000003811 61.0
HKD2_k127_5127344_15 Domain of Unknown function (DUF542) K07322 - - 0.000004301 56.0
HKD2_k127_5127344_16 FecR protein - - - 0.0006684 51.0
HKD2_k127_5127344_3 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 375.0
HKD2_k127_5127344_4 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 343.0
HKD2_k127_5127344_5 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 298.0
HKD2_k127_5127344_6 membrane organization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002049 288.0
HKD2_k127_5127344_7 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003454 264.0
HKD2_k127_5127344_9 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000000004276 166.0
HKD2_k127_5127707_0 Tetratricopeptide repeat - - - 1.773e-315 1031.0
HKD2_k127_5127707_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 614.0
HKD2_k127_5127707_2 Cytochrome c-type biogenesis protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 445.0
HKD2_k127_5127707_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000005823 198.0
HKD2_k127_5127707_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000009666 179.0
HKD2_k127_5127707_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000008002 134.0
HKD2_k127_5127707_6 COG1886 Flagellar motor switch type III secretory pathway protein K02416,K03225 - - 0.0000005795 61.0
HKD2_k127_5127707_7 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.00002003 53.0
HKD2_k127_5128268_0 MMPL family K07789 - - 0.0 1178.0
HKD2_k127_5128268_1 Belongs to the heat shock protein 70 family - - - 0.0 1083.0
HKD2_k127_5128268_10 short-chain dehydrogenase reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001806 283.0
HKD2_k127_5128268_12 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000002935 239.0
HKD2_k127_5128268_13 Domain of unknown function (DUF2760) - - - 0.000000000000000000000000000000000000000000000000000000000000000006264 234.0
HKD2_k127_5128268_14 PFAM Inward rectifier potassium channel K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000003799 233.0
HKD2_k127_5128268_15 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000002941 222.0
HKD2_k127_5128268_16 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000001768 178.0
HKD2_k127_5128268_17 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000207 164.0
HKD2_k127_5128268_18 cyclic nucleotide binding - - - 0.000000000000000000000000000000000005656 147.0
HKD2_k127_5128268_19 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000003071 144.0
HKD2_k127_5128268_2 MreB/Mbl protein - - - 9.652e-281 880.0
HKD2_k127_5128268_20 Thioesterase K07107 - - 0.00000000000000000000000006395 121.0
HKD2_k127_5128268_21 Belongs to the ompA family K03640 - - 0.000000000000000000000008142 110.0
HKD2_k127_5128268_22 Cysteine-rich secretory protein family - - - 0.00000000000000000000003905 111.0
HKD2_k127_5128268_23 Protein of unknown function (DUF2938) - - - 0.00000000000005025 83.0
HKD2_k127_5128268_24 - - - - 0.00000000002817 70.0
HKD2_k127_5128268_25 negative regulation of translational initiation - - - 0.00000001907 64.0
HKD2_k127_5128268_3 Glycosyl hydrolase family 1 - - - 1.43e-209 658.0
HKD2_k127_5128268_4 AMP-binding enzyme K01897 - 6.2.1.3 7.425e-201 643.0
HKD2_k127_5128268_5 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 415.0
HKD2_k127_5128268_6 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 385.0
HKD2_k127_5128268_7 Acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 362.0
HKD2_k127_5128268_8 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 346.0
HKD2_k127_5128268_9 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002565 303.0
HKD2_k127_5128853_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 621.0
HKD2_k127_5128853_1 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 502.0
HKD2_k127_5128853_10 Cytochrome c - - - 0.0000000000000000000006902 112.0
HKD2_k127_5128853_11 response to antibiotic - - - 0.000000000000000003077 100.0
HKD2_k127_5128853_12 Domain of unknown function (DUF4412) - - - 0.0000000000000006966 91.0
HKD2_k127_5128853_13 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000005312 85.0
HKD2_k127_5128853_14 protein secretion K03116 - - 0.0000000000004556 71.0
HKD2_k127_5128853_15 NHL repeat - - - 0.000000000001375 80.0
HKD2_k127_5128853_16 protein secretion K03116 - - 0.000000000008041 66.0
HKD2_k127_5128853_2 4Fe-4S single cluster domain K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 475.0
HKD2_k127_5128853_3 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 474.0
HKD2_k127_5128853_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 356.0
HKD2_k127_5128853_5 fructose 1,6-bisphosphate 1-phosphatase activity K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 343.0
HKD2_k127_5128853_6 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000001008 221.0
HKD2_k127_5128853_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000005884 195.0
HKD2_k127_5128853_9 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000002013 130.0
HKD2_k127_5130070_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 445.0
HKD2_k127_5130070_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 412.0
HKD2_k127_5130070_2 Periplasmic binding protein LacI transcriptional regulator K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 376.0
HKD2_k127_5130070_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 307.0
HKD2_k127_5130070_4 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000143 265.0
HKD2_k127_5130999_0 Aldehyde dehydrogenase - - - 9.948e-208 657.0
HKD2_k127_5130999_1 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 482.0
HKD2_k127_5130999_2 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 462.0
HKD2_k127_5130999_3 Repeat of Unknown Function (DUF347) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 306.0
HKD2_k127_5130999_4 COGs COG0607 Rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000000002712 164.0
HKD2_k127_5130999_5 - - - - 0.0000000000000000000000000000002013 130.0
HKD2_k127_5130999_6 Twin-arginine translocation pathway signal protein - - - 0.000000000001953 73.0
HKD2_k127_5131608_0 DEAD DEAH box K03724 - - 0.0 1429.0
HKD2_k127_5131608_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 385.0
HKD2_k127_5131608_2 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001283 293.0
HKD2_k127_5131608_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003079 283.0
HKD2_k127_5131608_4 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000006773 251.0
HKD2_k127_5131608_5 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000046 163.0
HKD2_k127_5131608_6 - - - - 0.0000000000000000000000000000000001969 148.0
HKD2_k127_5131608_8 Acid phosphatase homologues - - - 0.0000002434 62.0
HKD2_k127_5136002_0 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 477.0
HKD2_k127_5136002_1 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000001517 213.0
HKD2_k127_5136002_2 cellulose binding - - - 0.00000002007 66.0
HKD2_k127_5137532_0 Tetratricopeptide repeat - - - 6.758e-252 799.0
HKD2_k127_5140663_0 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 335.0
HKD2_k127_5140663_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000003459 204.0
HKD2_k127_5140663_2 Galactose oxidase, central domain - - - 0.00000135 60.0
HKD2_k127_5142960_0 COG2067 Long-chain fatty acid transport protein K06076 - - 0.0000000004026 67.0
HKD2_k127_5150797_0 long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 405.0
HKD2_k127_5150797_1 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 373.0
HKD2_k127_5150797_10 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000004619 98.0
HKD2_k127_5150797_2 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 348.0
HKD2_k127_5150797_3 PFAM Inward rectifier potassium channel K08715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003505 281.0
HKD2_k127_5150797_4 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005147 257.0
HKD2_k127_5150797_5 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000001943 218.0
HKD2_k127_5150797_6 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000378 162.0
HKD2_k127_5150797_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000002383 133.0
HKD2_k127_5150797_8 Protease prsW family - - - 0.00000000000000000000000000000002319 139.0
HKD2_k127_5150797_9 protein secretion K03116,K03117 GO:0003674,GO:0005215 - 0.0000000000000000000000002434 112.0
HKD2_k127_5151240_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 435.0
HKD2_k127_5151240_1 response regulator K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 328.0
HKD2_k127_5151240_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000007582 171.0
HKD2_k127_5151240_3 Domain of unknown function (DUF4132) - - - 0.000000000000000000000000000000000000006035 155.0
HKD2_k127_5151240_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0000000000000000000000000000000000006983 142.0
HKD2_k127_5151240_5 Tetratricopeptide repeat - - - 0.00000000000000000000000006826 119.0
HKD2_k127_5151240_6 AhpC/TSA family - - - 0.000001603 56.0
HKD2_k127_5160140_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 522.0
HKD2_k127_5160140_11 CHAP domain protein K21471 - - 0.00001316 57.0
HKD2_k127_5160140_2 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 351.0
HKD2_k127_5160140_3 response regulator K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 344.0
HKD2_k127_5160140_4 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002952 250.0
HKD2_k127_5160140_5 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000004594 219.0
HKD2_k127_5160140_6 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000000001028 190.0
HKD2_k127_5160140_8 DNA methylase K00571,K07316 - 2.1.1.72 0.000000000000000000000000000000000000000000000003512 190.0
HKD2_k127_516029_1 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000001478 189.0
HKD2_k127_516029_3 - - - - 0.0000007311 57.0
HKD2_k127_5165409_0 Alpha amylase, catalytic domain K05343 - 3.2.1.1,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 328.0
HKD2_k127_5165409_1 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 301.0
HKD2_k127_5165409_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.0000000000000000000000000000000000000000001678 169.0
HKD2_k127_5167826_0 COG0208 Ribonucleotide reductase, beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 314.0
HKD2_k127_5167826_1 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000002686 206.0
HKD2_k127_5167826_2 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000003213 226.0
HKD2_k127_5167826_3 COG1121 ABC-type Mn Zn transport systems ATPase component K09817 - - 0.000000000000000000000000000000000000000000000000001724 192.0
HKD2_k127_5167826_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000004216 79.0
HKD2_k127_5167826_7 GPR1 FUN34 yaaH family protein K07034 - - 0.0000001134 61.0
HKD2_k127_5168264_0 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001925 284.0
HKD2_k127_5168264_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000003042 242.0
HKD2_k127_5169354_0 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 443.0
HKD2_k127_5169354_1 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 353.0
HKD2_k127_5169354_2 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000001747 192.0
HKD2_k127_5169354_3 Phosphate acyltransferases - - - 0.000000000000000000000000000000009904 136.0
HKD2_k127_5169354_4 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000000000000000000000000005304 134.0
HKD2_k127_5169354_5 PFAM Fatty acid desaturase - - - 0.00000000000000000000000000284 114.0
HKD2_k127_5169354_6 carboxylic ester hydrolase activity - - - 0.000000000000000001488 100.0
HKD2_k127_5169354_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 - 5.2.1.8 0.000000000009871 72.0
HKD2_k127_5172503_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 601.0
HKD2_k127_5172503_1 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 494.0
HKD2_k127_5172503_2 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 424.0
HKD2_k127_5172503_3 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 400.0
HKD2_k127_5172503_4 DTW K05812 - - 0.0000000000000000000000000000000000000000008557 175.0
HKD2_k127_5172503_5 iron ion homeostasis K04758 - - 0.0000002369 57.0
HKD2_k127_5180071_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 512.0
HKD2_k127_5180071_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 424.0
HKD2_k127_5180071_2 - - - - 0.00000000000000000000000000000000000000000003532 175.0
HKD2_k127_5180071_5 Belongs to the sigma-70 factor family K02405 - - 0.000000000000000000000000009753 119.0
HKD2_k127_5180071_7 COG0457 FOG TPR repeat - - - 0.0005479 52.0
HKD2_k127_518229_0 ATPase domain of DNA mismatch repair MUTS family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 335.0
HKD2_k127_518229_1 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000001083 153.0
HKD2_k127_518229_2 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000001067 156.0
HKD2_k127_518229_3 Molybdenum ABC transporter, permease K02018 - - 0.0000000000000000000000000000000009442 144.0
HKD2_k127_518229_4 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000004817 96.0
HKD2_k127_5190033_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 367.0
HKD2_k127_5190033_1 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 306.0
HKD2_k127_5190033_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002268 233.0
HKD2_k127_5190033_3 Tyrosine phosphatase family - - - 0.0000000000000000000000000000000000000000000001261 181.0
HKD2_k127_5190033_4 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000002539 152.0
HKD2_k127_5190033_5 - K07283 - - 0.0000000000000000000000000000000006468 145.0
HKD2_k127_5190033_6 PPIC-type PPIASE domain - - - 0.0000000000000000000022 96.0
HKD2_k127_5195417_0 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 323.0
HKD2_k127_5196577_0 MMPL family - - - 1.617e-199 648.0
HKD2_k127_5196577_1 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 541.0
HKD2_k127_5196577_10 PFAM Formylglycine-generating sulfatase enzyme K12132,K18912 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.14.99.50,2.7.11.1 0.00000000000000000000000000000000000000002145 174.0
HKD2_k127_5196577_11 TPM domain K06872 - - 0.00000000000000000000000000000003516 146.0
HKD2_k127_5196577_12 - - - - 0.00000000000000000000000007349 109.0
HKD2_k127_5196577_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000001756 116.0
HKD2_k127_5196577_14 PFAM CBS domain containing protein - - - 0.0000000000000000000003622 107.0
HKD2_k127_5196577_15 - - - - 0.0000000004182 68.0
HKD2_k127_5196577_16 Transcription factor zinc-finger - - - 0.00000002714 63.0
HKD2_k127_5196577_17 Septum formation - - - 0.0002569 51.0
HKD2_k127_5196577_2 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 410.0
HKD2_k127_5196577_3 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 366.0
HKD2_k127_5196577_4 Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 351.0
HKD2_k127_5196577_5 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 302.0
HKD2_k127_5196577_6 Belongs to the N(4) N(6)-methyltransferase family K07316 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 301.0
HKD2_k127_5196577_7 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008238 294.0
HKD2_k127_5196577_8 Fumarase C-terminus K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000001285 221.0
HKD2_k127_5196577_9 - - - - 0.00000000000000000000000000000000000000000000006142 175.0
HKD2_k127_5199909_0 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 2.972e-261 835.0
HKD2_k127_5199909_1 glutathionylspermidine amidase activity K01460 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008884,GO:0008885,GO:0016787,GO:0016810,GO:0016811,GO:0016874,GO:0016879,GO:0016880,GO:0044424,GO:0044444,GO:0044464 3.5.1.78,6.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 530.0
HKD2_k127_5199909_10 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000003436 132.0
HKD2_k127_5199909_12 Domain of unknown function (DUF4142) K08995 - - 0.0000000002786 70.0
HKD2_k127_5199909_5 phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit K00479,K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 343.0
HKD2_k127_5199909_6 membrane K08989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 327.0
HKD2_k127_5199909_7 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 304.0
HKD2_k127_5199909_8 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000001785 227.0
HKD2_k127_5201147_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 402.0
HKD2_k127_5201147_1 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 312.0
HKD2_k127_5201147_2 - - - - 0.0000000000000000000000000000000000000000002546 180.0
HKD2_k127_5201147_3 PFAM Protein kinase domain K08309 - - 0.0000000000000000000000000000004217 134.0
HKD2_k127_5201147_4 Transposase - - - 0.00000000000000000000000001004 111.0
HKD2_k127_5201147_5 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.000000000000001987 90.0
HKD2_k127_5201147_6 PFAM Insertion element protein - - - 0.000000000009521 66.0
HKD2_k127_5201147_7 PFAM Insertion element protein - - - 0.00000000003298 64.0
HKD2_k127_5201147_8 COG5659 FOG Transposase - - - 0.0000004287 53.0
HKD2_k127_5201147_9 amine dehydrogenase activity - - - 0.00001617 55.0
HKD2_k127_5212371_0 PFAM ABC transporter K01990,K13926 - - 0.0 1367.0
HKD2_k127_5212371_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 291.0
HKD2_k127_5212371_2 Biotin-lipoyl like K01993 - - 0.000000000000000000000000002115 112.0
HKD2_k127_5213416_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 351.0
HKD2_k127_5213416_1 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000109 104.0
HKD2_k127_5219191_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 502.0
HKD2_k127_5224309_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 489.0
HKD2_k127_5224309_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 471.0
HKD2_k127_5224309_10 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008697 301.0
HKD2_k127_5224309_11 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003397 276.0
HKD2_k127_5224309_12 virulence factor implicated in the pathogenesis of mycobacterium tuberculosis at the level of intracellular survival, by the alteration of cell signaling events or by direct cytotoxicity catalytic activity a phosphatidylcholine H(2)O 1,2- diacylglycerol choline phosphate K01114 GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006629,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009405,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0034480,GO:0035821,GO:0042578,GO:0044003,GO:0044238,GO:0044403,GO:0044419,GO:0044464,GO:0051701,GO:0051704,GO:0051817,GO:0052008,GO:0052043,GO:0052111,GO:0052185,GO:0052188,GO:0052368,GO:0071704,GO:0071944,GO:1901575 3.1.4.3 0.0000000000000000000000000000000000000001408 168.0
HKD2_k127_5224309_13 histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000005636 155.0
HKD2_k127_5224309_14 - - - - 0.00000000000000000000000000002698 127.0
HKD2_k127_5224309_15 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000001245 123.0
HKD2_k127_5224309_16 Tetratricopeptide repeat - - - 0.00000000000000000000000006299 121.0
HKD2_k127_5224309_19 Leucine carboxyl methyltransferase - - - 0.000000000000004234 85.0
HKD2_k127_5224309_2 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 478.0
HKD2_k127_5224309_20 Bacterial regulatory proteins, tetR family - - - 0.0000000002382 69.0
HKD2_k127_5224309_21 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000004508 61.0
HKD2_k127_5224309_22 Domain of unknown function (DUF4333) - - - 0.00000397 49.0
HKD2_k127_5224309_23 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity K16038 - - 0.000009038 57.0
HKD2_k127_5224309_24 - - - - 0.0003077 52.0
HKD2_k127_5224309_3 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 454.0
HKD2_k127_5224309_4 transmembrane transport K03442,K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 386.0
HKD2_k127_5224309_5 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 363.0
HKD2_k127_5224309_6 S1 domain K00243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 354.0
HKD2_k127_5224309_7 polysaccharide biosynthetic process K06409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 336.0
HKD2_k127_5224309_8 Proposed nucleic acid binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 323.0
HKD2_k127_5224309_9 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005239 295.0
HKD2_k127_5228217_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 546.0
HKD2_k127_5228217_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 300.0
HKD2_k127_5228217_2 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.000000000000000000000556 100.0
HKD2_k127_5228217_3 outer membrane efflux protein - - - 0.000000000000001017 84.0
HKD2_k127_522824_1 von willebrand factor, type A K07114 - - 0.00000000000000000000000000009719 131.0
HKD2_k127_5230733_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 512.0
HKD2_k127_5230733_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 331.0
HKD2_k127_5230733_2 LysM domain - - - 0.0000001072 62.0
HKD2_k127_5243564_0 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 365.0
HKD2_k127_5243564_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K17722 - 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 372.0
HKD2_k127_5243564_2 4Fe-4S dicluster domain K17723 - 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 342.0
HKD2_k127_5245595_0 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 347.0
HKD2_k127_5245595_1 - - - - 0.00000000000000000000000000000000001818 140.0
HKD2_k127_5245595_2 - - - - 0.00000000002173 66.0
HKD2_k127_5248519_0 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 347.0
HKD2_k127_5248519_1 COG0618 Exopolyphosphatase-related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 323.0
HKD2_k127_5248519_3 dehydrogenase complex catalyzes the overall conversion of - - - 0.000000000000000000000000008572 126.0
HKD2_k127_5248519_4 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000006834 95.0
HKD2_k127_5248519_5 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000008014 90.0
HKD2_k127_5248519_6 Bacterial Ig-like domain 2 - - - 0.0000000001343 71.0
HKD2_k127_5249922_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 3.389e-196 629.0
HKD2_k127_5249922_1 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 315.0
HKD2_k127_5249922_2 Glutamine amidotransferases class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 290.0
HKD2_k127_5249922_3 PFAM chorismate K01665 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000166 274.0
HKD2_k127_5249922_4 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000007684 178.0
HKD2_k127_5249922_6 TIGRFAM TIGR03790 family protein - - - 0.00000001568 66.0
HKD2_k127_5249922_7 small periplasmic lipoprotein - - - 0.00000008392 61.0
HKD2_k127_5249922_8 Dephospho-CoA kinase K00859 - 2.7.1.24 0.00009822 47.0
HKD2_k127_5255559_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 2.446e-247 777.0
HKD2_k127_5258537_0 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 321.0
HKD2_k127_5258537_1 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000002086 252.0
HKD2_k127_5258537_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000418 201.0
HKD2_k127_5258537_3 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000007432 160.0
HKD2_k127_5258537_4 - - - - 0.0000000000000000000000000000000000000007011 151.0
HKD2_k127_5276343_0 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 390.0
HKD2_k127_5276343_1 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000003413 189.0
HKD2_k127_5276343_2 Archaeal transcriptional regulator TrmB - - - 0.000000000000000000000000000000000002808 154.0
HKD2_k127_5276343_4 transcriptional regulator - - - 0.00007202 54.0
HKD2_k127_5277140_0 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007987 520.0
HKD2_k127_5277140_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 431.0
HKD2_k127_5277140_2 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000001258 195.0
HKD2_k127_5277140_3 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000002718 196.0
HKD2_k127_5277140_4 IgGFc binding protein - - - 0.000000000000009145 76.0
HKD2_k127_5282291_0 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 371.0
HKD2_k127_5282291_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006874 293.0
HKD2_k127_5282291_2 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000006331 200.0
HKD2_k127_5282291_3 Periplasmic protein TonB links inner and outer membranes - - - 0.00000000000000000000000000005385 120.0
HKD2_k127_5282291_4 Aminotransferase class I and II K14267 - 2.6.1.17 0.0000000000000000001499 96.0
HKD2_k127_5282444_0 Ribonuclease E/G family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 437.0
HKD2_k127_5282444_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 355.0
HKD2_k127_5282444_2 ABC-2 family transporter protein - - - 0.000000000000000000000006178 112.0
HKD2_k127_5282444_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000001294 60.0
HKD2_k127_5285088_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 538.0
HKD2_k127_5285088_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 509.0
HKD2_k127_5285088_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 360.0
HKD2_k127_5285088_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 335.0
HKD2_k127_5285088_5 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 329.0
HKD2_k127_5285088_6 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 307.0
HKD2_k127_5285088_7 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 299.0
HKD2_k127_5285088_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000001291 231.0
HKD2_k127_5285088_9 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000001302 130.0
HKD2_k127_5289344_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 5.092e-213 680.0
HKD2_k127_5289344_1 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000001895 179.0
HKD2_k127_5289344_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.00004229 53.0
HKD2_k127_5289344_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000007707 168.0
HKD2_k127_5289344_3 - - - - 0.00000000000000000000000000000000000008907 148.0
HKD2_k127_5289344_5 - - - - 0.0000000000000000000000000009857 126.0
HKD2_k127_5289344_6 - - - - 0.0000000000000000000004243 101.0
HKD2_k127_5289344_7 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000002748 76.0
HKD2_k127_5289344_8 Protein of unknown function (DUF2752) - - - 0.000000000001412 74.0
HKD2_k127_5289344_9 - - - - 0.000000273 58.0
HKD2_k127_5295991_0 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000000000000000141 169.0
HKD2_k127_5300232_0 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.00000000000000000000000000000000006041 143.0
HKD2_k127_5300232_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000002232 102.0
HKD2_k127_5301753_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000002049 221.0
HKD2_k127_5301753_1 B domain of TMEM189, localisation domain K20656 - - 0.00000000000000000000000000000000000000000000000000000000567 211.0
HKD2_k127_5301753_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000535 171.0
HKD2_k127_5301753_3 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000004184 138.0
HKD2_k127_5301753_4 oxidoreductase activity K07114 - - 0.000000000000000002408 98.0
HKD2_k127_5302222_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.141e-209 663.0
HKD2_k127_5302222_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 608.0
HKD2_k127_5302222_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 552.0
HKD2_k127_5302222_3 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 393.0
HKD2_k127_5302222_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003911 272.0
HKD2_k127_5302222_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000004464 137.0
HKD2_k127_5302222_7 PilZ domain - - - 0.000000000000000000000000000001347 141.0
HKD2_k127_5302222_8 Binds to the 23S rRNA K02939 - - 0.000000004119 58.0
HKD2_k127_5302787_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000002031 172.0
HKD2_k127_5302787_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000002175 156.0
HKD2_k127_5302787_2 amine dehydrogenase activity - - - 0.000000000000000006145 95.0
HKD2_k127_5320324_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 311.0
HKD2_k127_5348072_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 565.0
HKD2_k127_5348072_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 291.0
HKD2_k127_5348072_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000002498 224.0
HKD2_k127_5348072_3 - - - - 0.00000000000000001968 92.0
HKD2_k127_5350943_0 Bacterial-like globin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 398.0
HKD2_k127_5350943_1 PFAM Dual specificity protein phosphatase K14165 - 3.1.3.16,3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000003475 285.0
HKD2_k127_5350943_10 - - - - 0.0000000939 64.0
HKD2_k127_5350943_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000002952 231.0
HKD2_k127_5350943_3 transcription factor binding - - - 0.0000000000000000000000000000000000000000000000004562 178.0
HKD2_k127_5350943_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000005639 155.0
HKD2_k127_5350943_5 GTP binding K06883 - - 0.00000000000000000000000000000000000001974 160.0
HKD2_k127_5350943_6 transcription factor binding - - - 0.0000000000000000000000000000001216 138.0
HKD2_k127_5350943_8 Two component, sigma54 specific, transcriptional regulator, Fis family protein - - - 0.00000000000000000003572 96.0
HKD2_k127_5350943_9 response regulator - - - 0.00000001654 68.0
HKD2_k127_535165_0 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001333 268.0
HKD2_k127_535165_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000001273 169.0
HKD2_k127_535165_2 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000001135 158.0
HKD2_k127_5352483_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 458.0
HKD2_k127_5352483_1 Cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 369.0
HKD2_k127_5352483_2 The glycine cleavage system catalyzes the degradation of glycine K00605,K11053 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000004246 207.0
HKD2_k127_5352483_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000003798 156.0
HKD2_k127_5352483_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000001595 69.0
HKD2_k127_5368713_0 Acyltransferase family - - - 0.0000000000000000000000004305 106.0
HKD2_k127_5368713_1 NLP P60 protein - - - 0.00000000004665 75.0
HKD2_k127_5369582_0 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 341.0
HKD2_k127_5369582_1 Rifampin ADP-ribosyl transferase - - - 0.000000000000000000000000000000000000005325 158.0
HKD2_k127_5369582_2 Protein of unknown function (DUF2505) - - - 0.000000000000000000000000000004207 125.0
HKD2_k127_5371565_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 375.0
HKD2_k127_5371565_1 oligosaccharyl transferase activity - - - 0.000001511 60.0
HKD2_k127_537558_0 Family membership - - - 6.2e-262 851.0
HKD2_k127_537558_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000003481 206.0
HKD2_k127_537558_3 CAAX amino terminal protease family - - - 0.00000000000000000000000000000000006702 154.0
HKD2_k127_5386599_0 serine threonine protein kinase - - - 1.923e-233 755.0
HKD2_k127_5386599_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.183e-227 718.0
HKD2_k127_5386599_10 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000001429 246.0
HKD2_k127_5386599_11 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000001496 227.0
HKD2_k127_5386599_12 - - - - 0.00000000000000000000000000000000000008463 157.0
HKD2_k127_5386599_13 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000002006 117.0
HKD2_k127_5386599_15 Signal transduction histidine kinase regulating C4-dicarboxylate transport system K10125 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000009001 100.0
HKD2_k127_5386599_16 Domain of unknown function (DUF2383) - - - 0.000000000006898 74.0
HKD2_k127_5386599_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.214e-198 625.0
HKD2_k127_5386599_3 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 435.0
HKD2_k127_5386599_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 402.0
HKD2_k127_5386599_5 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 370.0
HKD2_k127_5386599_6 KR domain K14189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 292.0
HKD2_k127_5386599_7 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 288.0
HKD2_k127_5386599_8 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 297.0
HKD2_k127_5386599_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001273 256.0
HKD2_k127_5386974_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001353 273.0
HKD2_k127_5386974_1 - - - - 0.000000000000000000000000000000000000000000085 166.0
HKD2_k127_5388910_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 317.0
HKD2_k127_5388910_1 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000001328 216.0
HKD2_k127_5389906_0 Involved in the tonB-independent uptake of proteins - - - 7.432e-204 653.0
HKD2_k127_5389906_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 520.0
HKD2_k127_5389906_2 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 454.0
HKD2_k127_5389906_3 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 334.0
HKD2_k127_5389906_4 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 334.0
HKD2_k127_5389906_5 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000323 271.0
HKD2_k127_5389906_6 PilT protein domain protein - - - 0.000000000000000000000000000000000000000000000000009133 200.0
HKD2_k127_5389906_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000504 194.0
HKD2_k127_5389906_8 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.000000000000000000002581 93.0
HKD2_k127_5389906_9 - - - - 0.0000001368 63.0
HKD2_k127_5390738_0 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 504.0
HKD2_k127_5390738_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 376.0
HKD2_k127_5390738_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 329.0
HKD2_k127_5390738_3 YceI-like domain - - - 0.000000000000000000000000000000000000000000000005987 177.0
HKD2_k127_5390738_4 Cytochrome c - - - 0.000000000000000000000000000000000000000000003736 179.0
HKD2_k127_5390738_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000002761 117.0
HKD2_k127_5394266_0 NAD binding K00333,K05579,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 328.0
HKD2_k127_5394266_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000004571 227.0
HKD2_k127_5396368_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 545.0
HKD2_k127_5396368_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005341 264.0
HKD2_k127_5396368_2 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000006299 193.0
HKD2_k127_5396368_3 LytTr DNA-binding domain K02477,K07705 - - 0.000000000000000000000000000000000000000000002809 184.0
HKD2_k127_5396368_4 YCII-related domain - - - 0.000000000000000000000000000000000000000000003433 166.0
HKD2_k127_5396368_5 - - - - 0.000000000000000000000000000000000000000002372 160.0
HKD2_k127_5396368_6 Biopolymer transport protein ExbD/TolR - - - 0.0000000000001994 72.0
HKD2_k127_5403463_0 - - - - 1.588e-222 724.0
HKD2_k127_5403463_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 413.0
HKD2_k127_5403463_10 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000000000001137 123.0
HKD2_k127_5403463_12 Rieske 2Fe-2S K05710 - - 0.000000004841 61.0
HKD2_k127_5403463_2 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 322.0
HKD2_k127_5403463_3 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 324.0
HKD2_k127_5403463_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003096 243.0
HKD2_k127_5403463_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000009705 237.0
HKD2_k127_5403463_6 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000001098 210.0
HKD2_k127_5403463_7 Glycosyl hydrolases family 25 K07273 - - 0.0000000000000000000000000000000000000000000000000005083 192.0
HKD2_k127_5403463_8 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000000000000000009186 197.0
HKD2_k127_5403463_9 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000001138 149.0
HKD2_k127_5411353_0 PEGA domain K02014 - - 4.913e-234 779.0
HKD2_k127_5411353_1 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 457.0
HKD2_k127_5411353_2 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 318.0
HKD2_k127_5411353_3 oxidoreductase activity K07114 - - 0.000000002231 69.0
HKD2_k127_5414323_0 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 433.0
HKD2_k127_5414323_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001374 278.0
HKD2_k127_5414323_2 Dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.000000000000000000000000000000000000000000000000000000000005024 218.0
HKD2_k127_5414323_3 peptidylprolyl isomerase K01802 - 5.2.1.8 0.000541 51.0
HKD2_k127_5426527_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000006818 198.0
HKD2_k127_5426527_1 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000003578 158.0
HKD2_k127_5426527_2 Aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000004117 163.0
HKD2_k127_5426527_3 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000238 127.0
HKD2_k127_5426527_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000431 72.0
HKD2_k127_5433740_0 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 350.0
HKD2_k127_5433740_1 phosphorelay signal transduction system K01768,K10941,K21405 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001884 269.0
HKD2_k127_5433740_10 cheY-homologous receiver domain - - - 0.0005155 46.0
HKD2_k127_5433740_11 response regulator - - - 0.0008164 48.0
HKD2_k127_5433740_2 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004694 248.0
HKD2_k127_5433740_3 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001332 236.0
HKD2_k127_5433740_4 Seven times multi-haem cytochrome CxxCH K10535 - 1.7.2.6 0.000000000000000000000000000000000000000000000000005224 201.0
HKD2_k127_5433740_6 Cytosol aminopeptidase family, N-terminal domain - - - 0.00000000000000000000000000000000000004049 149.0
HKD2_k127_5433740_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000005546 118.0
HKD2_k127_5433740_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000001214 92.0
HKD2_k127_5433740_9 PFAM Cytochrome C - - - 0.0003866 53.0
HKD2_k127_5434636_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1268.0
HKD2_k127_5434636_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 2.205e-233 736.0
HKD2_k127_5434636_2 Protein kinase; unclassified specificity. K12132 - 2.7.11.1 9.311e-202 660.0
HKD2_k127_5434636_3 drug transmembrane transporter activity K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 437.0
HKD2_k127_5434636_4 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000006041 182.0
HKD2_k127_5434636_6 Belongs to the ompA family K03640 - - 0.00000000000000000003194 100.0
HKD2_k127_5434636_7 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000001045 73.0
HKD2_k127_5453148_0 PFAM SpoVR family protein K06415 - - 4.496e-229 731.0
HKD2_k127_5453148_1 Belongs to the UPF0229 family K09786 - - 0.000000000000000000000000000000000000000000000000000000000000000000001457 236.0
HKD2_k127_5453148_2 Domain of unknown function (DUF4398) - - - 0.00000000000004733 83.0
HKD2_k127_5453148_3 Domain of unknown function (DUF4398) - - - 0.00000008098 59.0
HKD2_k127_5454161_0 Peptidase, M16 K07263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 3.217e-235 763.0
HKD2_k127_5454161_1 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 359.0
HKD2_k127_5454161_10 - - - - 0.0000005735 60.0
HKD2_k127_5454161_12 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000405 53.0
HKD2_k127_5454161_13 helix_turn_helix multiple antibiotic resistance protein - - - 0.0001814 51.0
HKD2_k127_5454161_14 Protein tyrosine kinase - - - 0.0008533 51.0
HKD2_k127_5454161_2 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000788 231.0
HKD2_k127_5454161_3 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000008837 207.0
HKD2_k127_5454161_4 Protein phosphatase 2A homologues, catalytic domain. - - - 0.000000000000000000000000000000000000006386 148.0
HKD2_k127_5454161_5 PEGA domain - - - 0.000000000000000000000000002763 125.0
HKD2_k127_5454161_7 gluconolactonase activity K01053 - 3.1.1.17 0.00000001841 68.0
HKD2_k127_5454161_8 amine dehydrogenase activity - - - 0.00000001896 67.0
HKD2_k127_5454161_9 FecR protein - - - 0.0000002726 62.0
HKD2_k127_5472302_0 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 627.0
HKD2_k127_5472302_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 405.0
HKD2_k127_5472302_3 Periplasmic protein TonB links inner and outer membranes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 385.0
HKD2_k127_5472302_4 Belongs to the bacterial histone-like protein family K05788 - - 0.000000000000000000000000000000000000000000000001271 188.0
HKD2_k127_5483760_0 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 412.0
HKD2_k127_5490081_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 401.0
HKD2_k127_5492885_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family K05991 - 3.2.1.123 0.000000000000000000000000000000000000000000000000007837 194.0
HKD2_k127_5492885_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000003349 156.0
HKD2_k127_5509393_0 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 342.0
HKD2_k127_5509393_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002159 291.0
HKD2_k127_5509393_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000001366 229.0
HKD2_k127_5514337_0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001186 249.0
HKD2_k127_5514337_1 Pectinacetylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002662 271.0
HKD2_k127_5514337_2 Proposed nucleic acid binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003513 248.0
HKD2_k127_5514337_3 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000004155 204.0
HKD2_k127_5514337_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437 - 2.1.1.185,2.1.1.34 0.00000000000000000000000000000000000000001041 170.0
HKD2_k127_552439_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 505.0
HKD2_k127_552439_1 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 380.0
HKD2_k127_552439_10 Membrane - - - 0.0000004097 63.0
HKD2_k127_552439_2 Protein kinase; unclassified specificity. K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000001698 197.0
HKD2_k127_552439_3 - - - - 0.000000000000000000000000000000000000000001445 164.0
HKD2_k127_552439_5 Belongs to the ompA family K03640 - - 0.000000000000000000000001906 117.0
HKD2_k127_552439_6 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000001211 115.0
HKD2_k127_552439_7 Cytochrome c - - - 0.0000000000000000001712 99.0
HKD2_k127_552439_8 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000001379 74.0
HKD2_k127_552439_9 Hemerythrin HHE cation binding domain - - - 0.000000006102 62.0
HKD2_k127_5528957_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.052e-308 957.0
HKD2_k127_5528957_1 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 319.0
HKD2_k127_5528957_2 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001565 255.0
HKD2_k127_5528957_3 Periplasmic binding protein K01999 - - 0.00000000000000000000000000002262 134.0
HKD2_k127_5528957_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000009302 114.0
HKD2_k127_5528957_5 DNA-binding transcription factor activity - - - 0.0000000000000004613 81.0
HKD2_k127_5530503_0 deoxyhypusine monooxygenase activity K01256,K02563,K08776,K12132 - 2.4.1.227,2.7.11.1,3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 329.0
HKD2_k127_5530503_1 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.00000000000000000000000007481 113.0
HKD2_k127_5531568_0 von Willebrand factor type A domain - - - 4.696e-215 685.0
HKD2_k127_5531568_1 Aerotolerance regulator N-terminal - - - 4.042e-201 640.0
HKD2_k127_5538013_0 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000008928 218.0
HKD2_k127_5538013_1 - - - - 0.000003888 61.0
HKD2_k127_5538013_2 Methyltransferase domain - - - 0.0002238 52.0
HKD2_k127_5540464_0 Belongs to the FPG family K05522 - 4.2.99.18 0.0000000000000000000000000000000000002893 145.0
HKD2_k127_5540464_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000003839 126.0
HKD2_k127_5540464_2 - - - - 0.000000000000000000001107 106.0
HKD2_k127_5551765_0 Periplasmic protein TonB links inner and outer membranes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 382.0
HKD2_k127_5551765_1 Large family of predicted nucleotide-binding domains K07175 - - 0.00000000000000000000000000000000000000000000000000000000007349 219.0
HKD2_k127_5551765_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000001762 194.0
HKD2_k127_5551765_4 isomerase activity - - - 0.000000000000004636 86.0
HKD2_k127_5559224_0 Lactonase, 7-bladed beta-propeller K07404 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000004057 215.0
HKD2_k127_5559224_1 - - - - 0.000000107 61.0
HKD2_k127_5559224_2 amine dehydrogenase activity - - - 0.000004993 57.0
HKD2_k127_5559224_3 SnoaL-like polyketide cyclase - - - 0.000009638 51.0
HKD2_k127_5561760_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 333.0
HKD2_k127_5561760_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000005636 177.0
HKD2_k127_5561760_2 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000004477 118.0
HKD2_k127_5561760_3 Ribosomal L32p protein family K02911 - - 0.000000000000000001682 86.0
HKD2_k127_5580439_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 292.0
HKD2_k127_5580439_1 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000005891 163.0
HKD2_k127_5583591_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 413.0
HKD2_k127_5583591_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 325.0
HKD2_k127_5583591_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 308.0
HKD2_k127_5583591_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 302.0
HKD2_k127_5583591_4 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000002665 157.0
HKD2_k127_5583591_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000726 125.0
HKD2_k127_5583591_6 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0000000000000003386 93.0
HKD2_k127_5583591_7 Transcriptional regulator - - - 0.00001842 54.0
HKD2_k127_5594212_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 471.0
HKD2_k127_5594212_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 425.0
HKD2_k127_5594212_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 392.0
HKD2_k127_5594212_3 Domain of unknown function (DUF4070) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 353.0
HKD2_k127_5594212_4 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008379 286.0
HKD2_k127_5594212_5 Acetoacetate decarboxylase (ADC) - - - 0.00000000000000000000000000000000000000000000000000000000007984 227.0
HKD2_k127_5594212_6 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000006357 195.0
HKD2_k127_5594212_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000009607 139.0
HKD2_k127_560137_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 465.0
HKD2_k127_560137_1 transferase activity, transferring glycosyl groups K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 421.0
HKD2_k127_560137_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 406.0
HKD2_k127_560137_3 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000002836 241.0
HKD2_k127_560137_4 Glycosyl transferase 4-like - - - 0.000000000000000000000000000001032 136.0
HKD2_k127_560137_5 response regulator K02481,K07713 - - 0.00000000000000000000000000005132 127.0
HKD2_k127_560137_6 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000001492 129.0
HKD2_k127_560137_7 Methyltransferase domain - - - 0.0000000000000000000000000008426 128.0
HKD2_k127_560137_8 Glycosyltransferase like family 2 - - - 0.00000000000000000007025 100.0
HKD2_k127_560137_9 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000006137 99.0
HKD2_k127_5616378_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 3.479e-197 637.0
HKD2_k127_5616378_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 576.0
HKD2_k127_5616378_11 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000000000000000000000002735 172.0
HKD2_k127_5616378_13 ThiS family K03636 - - 0.000000000000000000000000000000000000007561 146.0
HKD2_k127_5616378_2 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 578.0
HKD2_k127_5616378_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 480.0
HKD2_k127_5616378_4 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 449.0
HKD2_k127_5616378_5 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 413.0
HKD2_k127_5616378_6 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 350.0
HKD2_k127_5616378_8 domain protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000693 228.0
HKD2_k127_5616378_9 iron ion transport K07224 - - 0.000000000000000000000000000000000000000000000000000000000005174 219.0
HKD2_k127_5617105_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 574.0
HKD2_k127_5617105_1 Transcriptional regulator - - - 0.000000000000000000000000001299 117.0
HKD2_k127_5617105_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.00005684 46.0
HKD2_k127_5621399_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1043.0
HKD2_k127_5621399_1 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 368.0
HKD2_k127_5621399_2 Domain of unknown function (DUF4132) - - - 0.00000000000000000000000002295 119.0
HKD2_k127_5629899_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000491 226.0
HKD2_k127_5629899_1 - - - - 0.0000000000000000000000000000000000000000000000000000000001422 220.0
HKD2_k127_5629899_2 peptidase M20 - - - 0.000000000000000000000000000000000000000000001194 172.0
HKD2_k127_5629899_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000001102 151.0
HKD2_k127_5629899_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000005496 68.0
HKD2_k127_5629899_6 Protein kinase domain K12132 - 2.7.11.1 0.000003737 59.0
HKD2_k127_5629899_7 WD-40 repeat - - - 0.000009582 58.0
HKD2_k127_5629899_8 cell envelope organization K05807,K08309 - - 0.00002222 56.0
HKD2_k127_5631101_0 prohibitin homologues K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 479.0
HKD2_k127_5631101_1 glutamate--cysteine ligase K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 479.0
HKD2_k127_5631101_10 Band 7 protein K07192 - - 0.0000000000000000000005892 111.0
HKD2_k127_5631101_11 GHMP kinases N terminal domain K00938 - 2.7.4.2 0.000000000000000000009167 108.0
HKD2_k127_5631101_12 - - - - 0.0000005895 58.0
HKD2_k127_5631101_13 ubiE/COQ5 methyltransferase family - - - 0.00008968 55.0
HKD2_k127_5631101_2 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 447.0
HKD2_k127_5631101_3 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 388.0
HKD2_k127_5631101_4 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008076 284.0
HKD2_k127_5631101_5 mevalonate kinase K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000001222 246.0
HKD2_k127_5631101_6 Chemotaxis protein CheY K03413 - - 0.000000000000000000000000000000000000000000000000000000000000384 227.0
HKD2_k127_5631101_7 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000349 218.0
HKD2_k127_5631101_8 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000004146 194.0
HKD2_k127_5631101_9 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000002065 158.0
HKD2_k127_5634247_0 Tetratricopeptide repeat - - - 0.0 1733.0
HKD2_k127_5637710_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 364.0
HKD2_k127_5637710_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001128 291.0
HKD2_k127_5637710_2 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000001348 179.0
HKD2_k127_5637710_3 peptidyl-prolyl cis-trans isomerase activity K00645,K02597,K03769,K03771 - 2.3.1.39,5.2.1.8 0.0000000000000000000000000002632 132.0
HKD2_k127_5637710_4 - - - - 0.0000000000001997 81.0
HKD2_k127_5638202_0 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 406.0
HKD2_k127_5638202_1 peroxidase activity K00435 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 287.0
HKD2_k127_5638202_10 Peptidase M60-like family - - - 0.000000000000003649 87.0
HKD2_k127_5638202_11 mercury ion transmembrane transporter activity - - - 0.0000000000001278 78.0
HKD2_k127_5638202_12 - - - - 0.00000008567 58.0
HKD2_k127_5638202_13 23S rRNA-intervening sequence protein - - - 0.0004237 48.0
HKD2_k127_5638202_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000005217 264.0
HKD2_k127_5638202_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007222 247.0
HKD2_k127_5638202_4 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005803 241.0
HKD2_k127_5638202_5 Protein of unknown function (DUF1679) - - - 0.0000000000000000000000000000000000000000000000000000000000000567 235.0
HKD2_k127_5638202_6 GAF domain - - - 0.00000000000000000000000000000000000000000000000000002044 205.0
HKD2_k127_5638202_7 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000004848 157.0
HKD2_k127_5638202_8 SEC-C motif - - - 0.0000000000000000000007789 98.0
HKD2_k127_5638202_9 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 0.0000000000000000000008278 96.0
HKD2_k127_5638683_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 463.0
HKD2_k127_5638683_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 400.0
HKD2_k127_5638683_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 353.0
HKD2_k127_5638683_3 PFAM alpha beta hydrolase fold K03821 - - 0.0000009469 62.0
HKD2_k127_5638683_4 peptidyl-tyrosine sulfation - - - 0.000002056 60.0
HKD2_k127_5639599_0 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 475.0
HKD2_k127_5639599_1 TraB family - - - 0.000000000000000000000000000000001336 147.0
HKD2_k127_5649357_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000005197 201.0
HKD2_k127_5649357_1 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000006058 165.0
HKD2_k127_5651037_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 9.222e-291 899.0
HKD2_k127_5651037_1 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007425 282.0
HKD2_k127_5651037_2 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000004187 209.0
HKD2_k127_5651037_3 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000004528 208.0
HKD2_k127_5651037_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000001431 173.0
HKD2_k127_5651037_5 amidohydrolase - - - 0.00000000000000000000000000003504 124.0
HKD2_k127_565122_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001061 256.0
HKD2_k127_565122_1 - - - - 0.000000000000000000000000000000000000000000000000000000000004215 214.0
HKD2_k127_565122_2 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000695 168.0
HKD2_k127_565122_3 Proposed nucleic acid binding domain K10798 GO:0000002,GO:0000003,GO:0000122,GO:0000166,GO:0000228,GO:0000302,GO:0000303,GO:0000305,GO:0000715,GO:0000723,GO:0000724,GO:0000725,GO:0000785,GO:0000790,GO:0000791,GO:0000976,GO:0000977,GO:0000981,GO:0001012,GO:0001067,GO:0001228,GO:0001817,GO:0001818,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002225,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002786,GO:0002791,GO:0002792,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003002,GO:0003006,GO:0003254,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0003824,GO:0003909,GO:0003910,GO:0003950,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005667,GO:0005694,GO:0005700,GO:0005703,GO:0005719,GO:0005730,GO:0005737,GO:0005739,GO:0006139,GO:0006140,GO:0006163,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006282,GO:0006284,GO:0006289,GO:0006293,GO:0006294,GO:0006296,GO:0006302,GO:0006310,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006464,GO:0006471,GO:0006508,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006963,GO:0006974,GO:0006979,GO:0006996,GO:0006997,GO:0007000,GO:0007005,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007389,GO:0007552,GO:0007610,GO:0008069,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009303,GO:0009314,GO:0009408,GO:0009410,GO:0009411,GO:0009416,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009798,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009950,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010043,GO:0010212,GO:0010243,GO:0010332,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010611,GO:0010613,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010990,GO:0012501,GO:0012505,GO:0014070,GO:0014742,GO:0014743,GO:0015030,GO:0016043,GO:0016070,GO:0016072,GO:0016333,GO:0016334,GO:0016485,GO:0016540,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016886,GO:0017144,GO:0018130,GO:0018193,GO:0018209,GO:0018312,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0022616,GO:0023019,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030099,GO:0030154,GO:0030225,GO:0030331,GO:0030534,GO:0030575,GO:0030576,GO:0030707,GO:0030808,GO:0030809,GO:0030855,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031334,GO:0031347,GO:0031349,GO:0031960,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032042,GO:0032101,GO:0032103,GO:0032200,GO:0032204,GO:0032205,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032660,GO:0032700,GO:0032774,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033044,GO:0033143,GO:0033145,GO:0033146,GO:0033148,GO:0033365,GO:0033554,GO:0033683,GO:0033993,GO:0034248,GO:0034250,GO:0034504,GO:0034599,GO:0034605,GO:0034613,GO:0034614,GO:0034622,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034660,GO:0035079,GO:0035080,GO:0035257,GO:0035258,GO:0035363,GO:0036094,GO:0036211,GO:0040008,GO:0040009,GO:0042220,GO:0042221,GO:0042391,GO:0042393,GO:0042493,GO:0042592,GO:0042769,GO:0042802,GO:0042826,GO:0042981,GO:0043067,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043279,GO:0043388,GO:0043412,GO:0043434,GO:0043484,GO:0043502,GO:0043504,GO:0043523,GO:0043565,GO:0043900,GO:0043902,GO:0043933,GO:0044030,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0045087,GO:0045185,GO:0045595,GO:0045597,GO:0045739,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045944,GO:0045980,GO:0046034,GO:0046332,GO:0046483,GO:0047485,GO:0048037,GO:0048148,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048545,GO:0048583,GO:0048584,GO:0048609,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050707,GO:0050708,GO:0050709,GO:0050710,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050879,GO:0050881,GO:0050882,GO:0050896,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051052,GO:0051053,GO:0051054,GO:0051094,GO:0051098,GO:0051099,GO:0051101,GO:0051103,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051287,GO:0051385,GO:0051427,GO:0051457,GO:0051604,GO:0051606,GO:0051641,GO:0051651,GO:0051704,GO:0051716,GO:0051881,GO:0051900,GO:0051901,GO:0055086,GO:0060249,GO:0060255,GO:0060341,GO:0060359,GO:0060390,GO:0060391,GO:0060429,GO:0062012,GO:0062014,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070212,GO:0070412,GO:0070727,GO:0070848,GO:0070887,GO:0070911,GO:0071214,GO:0071241,GO:0071248,GO:0071294,GO:0071310,GO:0071363,GO:0071375,GO:0071417,GO:0071450,GO:0071451,GO:0071478,GO:0071482,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071824,GO:0071840,GO:0072347,GO:0072521,GO:0072595,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090092,GO:0090100,GO:0090257,GO:0090304,GO:0090305,GO:0097159,GO:0097305,GO:0097659,GO:0098687,GO:0098781,GO:0104004,GO:0140096,GO:0140097,GO:0140110,GO:1900180,GO:1900182,GO:1900371,GO:1900372,GO:1900407,GO:1900424,GO:1900426,GO:1900542,GO:1900543,GO:1901135,GO:1901214,GO:1901216,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901652,GO:1901653,GO:1901654,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902175,GO:1902531,GO:1902679,GO:1902680,GO:1902882,GO:1903201,GO:1903203,GO:1903376,GO:1903506,GO:1903507,GO:1903508,GO:1903516,GO:1903518,GO:1903530,GO:1903531,GO:1903578,GO:1903579,GO:1903827,GO:1903829,GO:1904044,GO:1904181,GO:1904356,GO:1904357,GO:1904645,GO:1904646,GO:1904760,GO:1904762,GO:1904950,GO:1905076,GO:1905077,GO:1990404,GO:1990837,GO:1990966,GO:2000112,GO:2000113,GO:2000677,GO:2000679,GO:2001020,GO:2001022,GO:2001141,GO:2001169,GO:2001170,GO:2001233,GO:2001242,GO:2001251 2.4.2.30 0.00000002411 63.0
HKD2_k127_5659758_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 326.0
HKD2_k127_5659758_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000004881 216.0
HKD2_k127_5665215_0 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 314.0
HKD2_k127_5665215_1 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000009512 155.0
HKD2_k127_5665215_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000006384 121.0
HKD2_k127_5665215_3 - - - - 0.0000000000000000000000000007956 125.0
HKD2_k127_5665215_4 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000001492 129.0
HKD2_k127_56746_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 8.65e-260 832.0
HKD2_k127_56746_1 SNF2 family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 577.0
HKD2_k127_56746_10 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000001736 130.0
HKD2_k127_56746_11 Anion-transporting ATPase - - - 0.00000000000000000000002154 116.0
HKD2_k127_56746_2 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 449.0
HKD2_k127_56746_3 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 387.0
HKD2_k127_56746_4 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K10680 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 371.0
HKD2_k127_56746_5 Protein of unknown function (DUF790) K09744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001432 287.0
HKD2_k127_56746_6 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000008375 228.0
HKD2_k127_56746_7 Domain of unknown function (DUF4405) - - - 0.000000000000000000000000000000000000000000001278 189.0
HKD2_k127_56746_8 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000001234 154.0
HKD2_k127_56746_9 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.00000000000000000000000000000165 135.0
HKD2_k127_5676680_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000005795 219.0
HKD2_k127_5676680_1 peptidase M20 - - - 0.00000000000000000000000000000000000000000001414 169.0
HKD2_k127_5678665_0 ADP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 372.0
HKD2_k127_5682766_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 351.0
HKD2_k127_5682766_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000003397 186.0
HKD2_k127_5697477_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.487e-221 696.0
HKD2_k127_5715663_0 Belongs to the peptidase S8 family - - - 8.059e-309 983.0
HKD2_k127_5715663_1 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 300.0
HKD2_k127_573344_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 584.0
HKD2_k127_573344_1 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000005329 198.0
HKD2_k127_573344_2 cell adhesion involved in biofilm formation - - - 0.0005739 51.0
HKD2_k127_5733445_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 349.0
HKD2_k127_5733445_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 306.0
HKD2_k127_5733445_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000002561 216.0
HKD2_k127_5733445_3 phosphate ion binding - - - 0.000000000000000000000000000000000000000000000000000000003819 220.0
HKD2_k127_5733445_4 - - - - 0.000000000000000000000000000002053 135.0
HKD2_k127_5741069_0 - - - - 2.979e-217 705.0
HKD2_k127_5741069_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 6.503e-213 669.0
HKD2_k127_5741069_2 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 432.0
HKD2_k127_5741069_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 321.0
HKD2_k127_5741069_4 PFAM Protein kinase domain K08309 - - 0.000000000000000000000000000000000000000000000000000001057 203.0
HKD2_k127_5748860_0 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 490.0
HKD2_k127_5748860_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 451.0
HKD2_k127_5748860_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 417.0
HKD2_k127_5748860_3 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 359.0
HKD2_k127_5748860_4 copper-translocating P-type ATPase K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 357.0
HKD2_k127_5748860_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 300.0
HKD2_k127_5748860_6 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006245 252.0
HKD2_k127_5748860_8 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000001884 179.0
HKD2_k127_5748860_9 Heavy metal-associated domain protein K07213 - - 0.00000000002416 67.0
HKD2_k127_5771741_0 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000003397 218.0
HKD2_k127_5771741_1 outer membrane efflux protein - - - 0.000000000000000000001525 109.0
HKD2_k127_5771741_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000008476 95.0
HKD2_k127_5771741_3 transcriptional regulator - - - 0.00000000000003169 75.0
HKD2_k127_5775805_0 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 466.0
HKD2_k127_5775805_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 454.0
HKD2_k127_5775805_2 Conserved hypothetical protein 698 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 338.0
HKD2_k127_5775805_3 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.000000000000000000000000000006665 136.0
HKD2_k127_589500_0 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 557.0
HKD2_k127_589500_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 482.0
HKD2_k127_589500_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 401.0
HKD2_k127_589500_3 Phosphopantetheine attachment site K02078 - - 0.000000000000000000000000000001505 123.0
HKD2_k127_5905915_0 protein involved in exopolysaccharide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 622.0
HKD2_k127_5905915_1 Peptidase family M3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 406.0
HKD2_k127_5905915_2 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 313.0
HKD2_k127_5905915_3 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000000000000000000000000000000000000000000000000000000000000383 241.0
HKD2_k127_5905915_5 cellulose binding - - - 0.0000000000007855 83.0
HKD2_k127_591600_0 AAA C-terminal domain K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 350.0
HKD2_k127_591600_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000154 154.0
HKD2_k127_591600_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000007683 66.0
HKD2_k127_591600_3 Putative 2OG-Fe(II) oxygenase - - - 0.00008186 56.0
HKD2_k127_591870_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000009838 87.0
HKD2_k127_591870_1 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000000898 91.0
HKD2_k127_591870_2 COG1846 Transcriptional regulators - - - 0.0005588 51.0
HKD2_k127_5922388_0 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 312.0
HKD2_k127_5922388_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000035 262.0
HKD2_k127_5922388_2 PhoD-like phosphatase K01113 - 3.1.3.1 0.0000000000000182 83.0
HKD2_k127_5948344_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 338.0
HKD2_k127_5948344_1 PFAM Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 334.0
HKD2_k127_5948344_2 Insulinase (Peptidase family M16) K07263 - - 0.0000000006614 72.0
HKD2_k127_5964314_0 AMP-binding enzyme K01897 - 6.2.1.3 1.778e-211 687.0
HKD2_k127_5964314_1 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 548.0
HKD2_k127_5964314_2 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 338.0
HKD2_k127_5964314_3 Phosphopantetheine attachment site - - - 0.000000000000000005384 93.0
HKD2_k127_5970471_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000003198 225.0
HKD2_k127_5970471_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000003354 178.0
HKD2_k127_5970471_2 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000001428 145.0
HKD2_k127_5970471_3 proteolysis - - - 0.00000000000000000000000000002669 127.0
HKD2_k127_5970471_4 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000002698 82.0
HKD2_k127_5987572_0 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 502.0
HKD2_k127_5987572_1 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 426.0
HKD2_k127_5987572_2 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 338.0
HKD2_k127_5987572_3 Binding-protein-dependent transport system inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 311.0
HKD2_k127_5987572_4 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001628 256.0
HKD2_k127_5987572_5 SPFH domain-Band 7 family - - - 0.0000000000000000000000001225 113.0
HKD2_k127_5987572_6 Alpha/beta hydrolase family - - - 0.0000000000000009038 89.0
HKD2_k127_5987572_7 zinc-ribbon domain - - - 0.000001487 57.0
HKD2_k127_6007_0 Type II and III secretion system protein K02453 - - 4.251e-209 674.0
HKD2_k127_6007_1 General secretion pathway protein C K02452 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001259 287.0
HKD2_k127_6007_2 response regulator K07713 - - 0.00000000000000001024 83.0
HKD2_k127_6059635_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 570.0
HKD2_k127_6059635_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000002231 252.0
HKD2_k127_6059635_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000002815 191.0
HKD2_k127_6084267_0 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 501.0
HKD2_k127_6084267_1 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 402.0
HKD2_k127_6096332_0 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 439.0
HKD2_k127_6096332_1 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 385.0
HKD2_k127_6096332_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000307 281.0
HKD2_k127_611088_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 413.0
HKD2_k127_611088_1 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 411.0
HKD2_k127_611088_2 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 313.0
HKD2_k127_611088_3 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004326 283.0
HKD2_k127_611088_4 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000001797 226.0
HKD2_k127_611088_5 - - - - 0.0000000000000000000000000000003392 143.0
HKD2_k127_6111853_0 PFAM Protein kinase domain - - - 0.0 1247.0
HKD2_k127_6111853_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 531.0
HKD2_k127_6111853_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 467.0
HKD2_k127_6111853_3 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 362.0
HKD2_k127_6111853_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000004862 250.0
HKD2_k127_6111853_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000001046 227.0
HKD2_k127_6111853_6 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000004123 235.0
HKD2_k127_6111853_7 Riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000004665 213.0
HKD2_k127_6111853_8 cell envelope organization K05807,K08309 - - 0.0000000000000000000000000000000001266 147.0
HKD2_k127_6111853_9 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000003697 134.0
HKD2_k127_6127346_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 424.0
HKD2_k127_6127346_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 339.0
HKD2_k127_6127346_2 - - - - 0.0000000000000000000000000000000000000000005318 171.0
HKD2_k127_6127346_5 Belongs to the sigma-70 factor family K02405 - - 0.00000000000000000000000001698 117.0
HKD2_k127_6127346_6 - - - - 0.0001034 49.0
HKD2_k127_6127346_7 COG0457 FOG TPR repeat - - - 0.0003908 52.0
HKD2_k127_613056_0 tRNA synthetases class II (D, K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 369.0
HKD2_k127_613056_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 329.0
HKD2_k127_613056_2 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.00000000000000000000000008257 110.0
HKD2_k127_613056_3 Bacterial export proteins, family 3 K02420 - - 0.000009981 56.0
HKD2_k127_61578_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 4.975e-220 700.0
HKD2_k127_61578_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 433.0
HKD2_k127_61578_2 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 321.0
HKD2_k127_61578_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K12132 - 2.7.11.1 0.000000000000000000000000000000000002053 151.0
HKD2_k127_61578_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000003532 142.0
HKD2_k127_61578_6 Acetyltransferase (GNAT) domain K03817 - - 0.00000000000000000000003957 107.0
HKD2_k127_61578_7 Glycosyl transferase family 2 - - - 0.00000000000000000000005643 100.0
HKD2_k127_6160489_0 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 387.0
HKD2_k127_6160489_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000005291 94.0
HKD2_k127_6160489_2 Ferredoxin K04755,K11107 - - 0.000000000000000006994 94.0
HKD2_k127_620158_0 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 330.0
HKD2_k127_620158_1 Predicted membrane protein (DUF2254) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009405,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003262 277.0
HKD2_k127_620158_2 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000001241 229.0
HKD2_k127_620158_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000004093 164.0
HKD2_k127_620158_4 Amino acid permease - - - 0.0000000000000000000000000000000000000009999 151.0
HKD2_k127_620158_5 Pseudouridine synthase K06180 - 5.4.99.23 0.00000000000000000000000000000005434 133.0
HKD2_k127_620158_6 Putative zinc-finger - - - 0.0001171 48.0
HKD2_k127_6306126_0 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 502.0
HKD2_k127_6306126_1 Peptidase dimerisation domain K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000007335 234.0
HKD2_k127_632100_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 451.0
HKD2_k127_632100_1 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 396.0
HKD2_k127_632100_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 319.0
HKD2_k127_632100_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 312.0
HKD2_k127_633362_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 407.0
HKD2_k127_633362_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000528 197.0
HKD2_k127_633362_3 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000003074 210.0
HKD2_k127_633362_4 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000001195 186.0
HKD2_k127_633362_5 Dual specificity phosphatase, catalytic domain - - - 0.0000000000000000000000000000001081 133.0
HKD2_k127_633362_6 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000003704 102.0
HKD2_k127_633362_7 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000005214 78.0
HKD2_k127_6353800_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 367.0
HKD2_k127_6353800_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000004075 168.0
HKD2_k127_6353800_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000008843 157.0
HKD2_k127_6353800_3 Protein of unknown function (DUF533) K06596 - - 0.00007111 51.0
HKD2_k127_635643_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 391.0
HKD2_k127_635643_1 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000197 126.0
HKD2_k127_635643_2 Extensin-like protein C-terminus - - - 0.00000000000000000000000000002808 130.0
HKD2_k127_635643_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.000000000000000000000000007581 116.0
HKD2_k127_6383542_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000009927 214.0
HKD2_k127_6383542_1 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000000004479 113.0
HKD2_k127_6387391_0 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 379.0
HKD2_k127_6387391_1 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 319.0
HKD2_k127_6387391_2 serine-type peptidase activity K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000004331 239.0
HKD2_k127_6387391_3 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000007135 249.0
HKD2_k127_6387391_4 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000002168 129.0
HKD2_k127_6387391_5 Oxidoreductase family, NAD-binding Rossmann fold K03810 - - 0.0000000000000000000001509 109.0
HKD2_k127_6387391_6 Stigma-specific protein, Stig1 - - - 0.00000000000000001758 88.0
HKD2_k127_6389464_0 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003174 276.0
HKD2_k127_6389464_1 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001122 245.0
HKD2_k127_6389464_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000009123 138.0
HKD2_k127_6393344_0 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 311.0
HKD2_k127_6393344_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000006116 183.0
HKD2_k127_6393344_2 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000005006 174.0
HKD2_k127_6393344_3 PEGA domain - - - 0.000000000000000000000000000000000000000008655 176.0
HKD2_k127_6393344_4 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000007437 124.0
HKD2_k127_6394265_0 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 421.0
HKD2_k127_6394265_1 belongs to the thioredoxin family K20543 - - 0.000000000000000000000000000000000000000000000000001245 205.0
HKD2_k127_6394265_2 SCP-2 sterol transfer family - - - 0.000488 48.0
HKD2_k127_6399943_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 2.588e-278 908.0
HKD2_k127_6399943_1 Heat shock 70 kDa protein K04043 - - 2.95e-273 850.0
HKD2_k127_6399943_2 Surface antigen - - - 3.726e-218 717.0
HKD2_k127_6399943_3 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000005289 250.0
HKD2_k127_6399943_4 metallopeptidase activity K03568 - - 0.000000000000000000000000000000000000000000000000000000000000001168 231.0
HKD2_k127_6399943_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000002978 190.0
HKD2_k127_6399943_6 - - - - 0.00000000000000000000000000000337 129.0
HKD2_k127_6399943_7 Protein of unknown function (DUF962) - - - 0.000000000000000000001532 98.0
HKD2_k127_6419036_0 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 412.0
HKD2_k127_6419036_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000005855 119.0
HKD2_k127_6419192_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 632.0
HKD2_k127_6419192_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 456.0
HKD2_k127_6419192_2 Major intrinsic protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 340.0
HKD2_k127_6419192_3 TRANSCRIPTIONal K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 314.0
HKD2_k127_6419192_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000002808 231.0
HKD2_k127_6419192_5 sporulation resulting in formation of a cellular spore - - - 0.000003845 55.0
HKD2_k127_6419320_0 Male sterility protein K01897 - 6.2.1.3 2.044e-249 790.0
HKD2_k127_6421014_0 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 481.0
HKD2_k127_6421542_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 7.379e-202 657.0
HKD2_k127_6421542_1 ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005485 391.0
HKD2_k127_6421542_2 ABC-type multidrug transport system ATPase component K21397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000051 278.0
HKD2_k127_6421542_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000007892 229.0
HKD2_k127_6421542_4 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000001302 189.0
HKD2_k127_6421542_5 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000001765 155.0
HKD2_k127_6429996_0 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 376.0
HKD2_k127_6429996_1 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008236 242.0
HKD2_k127_6429996_2 TLC ATP/ADP transporter K03301 - - 0.000000000000000989 91.0
HKD2_k127_6429996_3 AI-2E family transporter - - - 0.0000000007755 71.0
HKD2_k127_6430438_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 305.0
HKD2_k127_6430438_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000001112 183.0
HKD2_k127_6430438_2 YceI-like domain - - - 0.0000000000000000000000000000000000000000001425 164.0
HKD2_k127_6430438_3 Cytochrome c mono- and diheme variants - - - 0.000000000000000000000000000000000000000005368 169.0
HKD2_k127_6430438_4 deoxyhypusine monooxygenase activity K01387 - 3.4.24.3 0.00000000000000000000000000004681 135.0
HKD2_k127_6432629_0 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 434.0
HKD2_k127_6432629_1 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003647 287.0
HKD2_k127_6432629_2 Putative esterase - - - 0.0000000000001808 70.0
HKD2_k127_6433428_0 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000002879 239.0
HKD2_k127_6433428_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000002132 143.0
HKD2_k127_6433428_2 Cytochrome c - - - 0.000241 51.0
HKD2_k127_6436378_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000133 265.0
HKD2_k127_6436378_1 protein kinase activity K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000146 177.0
HKD2_k127_6436378_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000006131 147.0
HKD2_k127_6436378_3 Trypsin-like peptidase domain - - - 0.0000000000000000000000000165 115.0
HKD2_k127_6436378_4 - - - - 0.000000002485 70.0
HKD2_k127_6436378_5 BetI-type transcriptional repressor, C-terminal - - - 0.000004125 59.0
HKD2_k127_6439159_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 447.0
HKD2_k127_6439159_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 320.0
HKD2_k127_6442297_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.915e-260 815.0
HKD2_k127_6442297_1 AAA ATPase domain - - - 3.134e-243 796.0
HKD2_k127_6442297_11 - - - - 0.00000000000004092 82.0
HKD2_k127_6442297_12 - - - - 0.0000001498 64.0
HKD2_k127_6442297_2 Efflux ABC transporter, permease ATP-binding protein K06147 - - 1.149e-230 727.0
HKD2_k127_6442297_3 Belongs to the aldehyde dehydrogenase family - - - 2.651e-205 647.0
HKD2_k127_6442297_4 GMC oxidoreductase K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 589.0
HKD2_k127_6442297_5 PFAM multicopper oxidase type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 545.0
HKD2_k127_6442297_6 transferase activity, transferring glycosyl groups K09809 - 2.7.8.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 537.0
HKD2_k127_6442297_7 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 426.0
HKD2_k127_6442297_8 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 374.0
HKD2_k127_6442643_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007,K21787 - 2.7.9.2 1.136e-254 818.0
HKD2_k127_6442643_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000001931 233.0
HKD2_k127_6442643_2 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000009468 68.0
HKD2_k127_6443214_0 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001513 278.0
HKD2_k127_6443214_1 COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog K03088 - - 0.000000000000000000000000000000005722 132.0
HKD2_k127_64468_0 Sigma-54 interaction domain K02584 - - 3.03e-274 856.0
HKD2_k127_64468_1 PrkA AAA domain K07180 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 456.0
HKD2_k127_64468_2 Domain of unknown function (DUF4132) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000421 292.0
HKD2_k127_64468_3 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001705 245.0
HKD2_k127_64468_4 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000001545 199.0
HKD2_k127_64468_5 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000104 148.0
HKD2_k127_6450594_0 Serine Threonine protein kinase K12132 - 2.7.11.1 4.359e-266 844.0
HKD2_k127_6450594_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 331.0
HKD2_k127_6457709_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 564.0
HKD2_k127_6457709_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 418.0
HKD2_k127_6457709_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000002248 194.0
HKD2_k127_6457709_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000007349 109.0
HKD2_k127_646484_0 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 611.0
HKD2_k127_646484_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 497.0
HKD2_k127_646484_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 303.0
HKD2_k127_646484_3 Peptidase family M50 - - - 0.000000000000000000000000574 118.0
HKD2_k127_6465261_0 Zn-dependent proteases and their inactivated homologs K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 483.0
HKD2_k127_6465261_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 417.0
HKD2_k127_6465261_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 339.0
HKD2_k127_6465261_3 sequence-specific DNA binding K07726 - - 0.000000000000000000000003714 117.0
HKD2_k127_6469883_0 imidazolonepropionase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 421.0
HKD2_k127_6469883_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 329.0
HKD2_k127_6469883_2 peptidase inhibitor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000291 265.0
HKD2_k127_6469883_3 Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000002716 227.0
HKD2_k127_6469883_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000001684 191.0
HKD2_k127_6469883_6 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000000000000000000000003348 141.0
HKD2_k127_6469883_7 Transmembrane and TPR repeat-containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048878,GO:0050801,GO:0055065,GO:0055074,GO:0055080,GO:0065007,GO:0065008,GO:0072507,GO:0098771,GO:0098827 - 0.000000000001502 81.0
HKD2_k127_6469883_8 Prokaryotic N-terminal methylation motif K02650 - - 0.000000000005112 74.0
HKD2_k127_6469883_9 Tetratricopeptide repeat - - - 0.000006541 59.0
HKD2_k127_6474804_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 529.0
HKD2_k127_6474804_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001153 286.0
HKD2_k127_6474804_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000001412 202.0
HKD2_k127_6474804_3 PilZ domain - - - 0.00000000000000000000000000000000000000000000000000006233 198.0
HKD2_k127_6474804_4 PFAM DHH family - - - 0.000000000000000000009566 95.0
HKD2_k127_6474804_5 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000001134 89.0
HKD2_k127_6491608_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001187 258.0
HKD2_k127_6491608_1 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.00000000000000000000000000000000000000000000000112 177.0
HKD2_k127_6491608_2 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000003896 158.0
HKD2_k127_6491608_3 DNA-binding regulatory protein K03088 - - 0.00000000000000000000000000357 121.0
HKD2_k127_6509800_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 469.0
HKD2_k127_6509800_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000001187 258.0
HKD2_k127_6509800_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000003449 90.0
HKD2_k127_6511096_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.761e-211 680.0
HKD2_k127_6511096_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000001238 223.0
HKD2_k127_6511096_2 DHH family - - - 0.000000000000000000000000000000000000000000000000000000001388 216.0
HKD2_k127_6511096_3 heat shock protein binding K03686 - - 0.00000000000000000000000000118 130.0
HKD2_k127_6511096_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000001091 85.0
HKD2_k127_6511096_5 CAAX protease self-immunity K07052 - - 0.0003724 53.0
HKD2_k127_6513554_0 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 358.0
HKD2_k127_6513554_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000003008 223.0
HKD2_k127_6513554_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000004066 169.0
HKD2_k127_6521940_0 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001182 280.0
HKD2_k127_6521940_1 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000001027 215.0
HKD2_k127_6521940_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000005723 214.0
HKD2_k127_6521940_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000005865 126.0
HKD2_k127_6528672_0 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000008544 161.0
HKD2_k127_6528672_1 SURF4 family K15977 - - 0.000000000000000000000000000000000000001623 153.0
HKD2_k127_6528672_2 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0000000000000000000000000000000004524 132.0
HKD2_k127_6528672_3 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000005476 98.0
HKD2_k127_6528672_4 N-4 methylation of cytosine - - - 0.0000000000001222 72.0
HKD2_k127_6530785_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 317.0
HKD2_k127_6530785_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001985 238.0
HKD2_k127_6530785_2 - - - - 0.00000000000000000000000000000000000000000000009977 184.0
HKD2_k127_6530785_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000008085 64.0
HKD2_k127_6530785_5 Belongs to the SlyX family K03745 - - 0.00001734 49.0
HKD2_k127_6533104_0 anaerobic sulfatase-maturating enzyme K06871 - - 0.0000000000005069 81.0
HKD2_k127_6533104_1 Ankyrin repeats (3 copies) - - - 0.000000002753 65.0
HKD2_k127_6534992_0 GAF domain - - - 1.217e-221 699.0
HKD2_k127_6534992_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 450.0
HKD2_k127_6534992_2 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 400.0
HKD2_k127_6534992_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000008786 250.0
HKD2_k127_6534992_4 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000001746 186.0
HKD2_k127_6534992_5 - - - - 0.000001695 59.0
HKD2_k127_6534992_6 Histidine kinase K03407,K13490 - 2.7.13.3 0.000003599 53.0
HKD2_k127_6539891_0 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 535.0
HKD2_k127_6539891_1 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 491.0
HKD2_k127_6539891_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 354.0
HKD2_k127_6539891_3 PFAM VanW family protein K18346 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006735 280.0
HKD2_k127_6539891_4 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000003092 227.0
HKD2_k127_6539891_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000004633 151.0
HKD2_k127_6539891_6 Cytochrome c - - - 0.00000000000000000000000000001309 124.0
HKD2_k127_6539891_7 - - - - 0.000000009228 66.0
HKD2_k127_6547825_1 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000002426 155.0
HKD2_k127_6547825_2 Putative diguanylate phosphodiesterase - - - 0.000000000000000315 88.0
HKD2_k127_6548448_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 519.0
HKD2_k127_6548448_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 481.0
HKD2_k127_6548448_2 DNA-binding transcription factor activity - - - 0.000000001873 65.0
HKD2_k127_6553945_0 cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 409.0
HKD2_k127_6553945_1 Oxygenase, catalysing oxidative methylation of damaged DNA - - - 0.0000000000000000000000000000003436 138.0
HKD2_k127_6553945_2 - - - - 0.0000000000000000000000005693 114.0
HKD2_k127_6553945_3 - - - - 0.000000000005362 75.0
HKD2_k127_6553945_4 Acetyltransferase (GNAT) domain - - - 0.0000002102 63.0
HKD2_k127_6553945_5 - K14627 - - 0.000009512 55.0
HKD2_k127_6556544_0 N-terminal domain of galactosyltransferase K20438 - 2.4.1.338 0.00000000000000000000000000000000001905 147.0
HKD2_k127_6556544_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000002323 119.0
HKD2_k127_6556544_2 Bacterial membrane protein, YfhO - - - 0.0000000000000000000001749 113.0
HKD2_k127_6556544_3 Belongs to the glycosyl hydrolase 26 family K01218,K01219,K05970,K19355 - 3.1.1.53,3.2.1.78,3.2.1.81 0.0000000000000000000006222 107.0
HKD2_k127_6556544_4 Iron-sulfur cluster-binding domain - - - 0.0000000000000000003587 102.0
HKD2_k127_6556544_5 4Fe-4S single cluster domain K06139 - - 0.000000000000000121 93.0
HKD2_k127_6556544_6 deacetylase - - - 0.000000005474 69.0
HKD2_k127_6556544_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000229 60.0
HKD2_k127_6556544_8 4Fe-4S single cluster domain - - - 0.00001285 58.0
HKD2_k127_6559134_0 translation initiation factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 359.0
HKD2_k127_6559134_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 351.0
HKD2_k127_6559134_10 TIGRFAM phosphate binding protein K02040 - - 0.000001187 60.0
HKD2_k127_6559134_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 335.0
HKD2_k127_6559134_3 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 334.0
HKD2_k127_6559134_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001036 290.0
HKD2_k127_6559134_5 Protein of unknown function (DUF2652) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001155 264.0
HKD2_k127_6559134_6 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000002759 213.0
HKD2_k127_6559134_7 Extradiol ring-cleavage dioxygenase K15777 - - 0.0000000000000000000000000000000000000000004952 172.0
HKD2_k127_6559276_0 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 386.0
HKD2_k127_6559276_1 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 340.0
HKD2_k127_6559276_2 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000344 255.0
HKD2_k127_6559276_3 PFAM Cation efflux - - - 0.0000000000000000000000000000000000000000000000000000000000000574 225.0
HKD2_k127_6559276_4 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000003198 145.0
HKD2_k127_6559276_5 Predicted membrane protein (DUF2085) - - - 0.00000000000000000001003 106.0
HKD2_k127_6559276_6 CHAT domain - - - 0.0000000002932 73.0
HKD2_k127_6560143_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 500.0
HKD2_k127_6560143_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 456.0
HKD2_k127_6560143_2 ATP-NAD kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000159 275.0
HKD2_k127_6560143_3 Zinc-dependent metalloprotease - - - 0.0000000000000000000000000000000000000000000000000000000000000004937 231.0
HKD2_k127_6560143_4 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000005177 215.0
HKD2_k127_6560143_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000001187 205.0
HKD2_k127_6560143_6 nUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000003052 176.0
HKD2_k127_6560143_7 - - - - 0.00000000000000000001571 99.0
HKD2_k127_6560143_9 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000003037 77.0
HKD2_k127_6565236_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.08e-228 719.0
HKD2_k127_6565236_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 405.0
HKD2_k127_6565236_11 Cadherin-like beta sandwich domain - - - 0.0000008329 61.0
HKD2_k127_6565236_2 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 304.0
HKD2_k127_6565236_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000002936 176.0
HKD2_k127_6565236_4 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000004527 141.0
HKD2_k127_6565236_8 TIGRFAM conserved repeat domain - - - 0.000000001085 70.0
HKD2_k127_6565646_0 Multicopper oxidase K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 519.0
HKD2_k127_6565646_1 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008483 280.0
HKD2_k127_6565646_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000352 208.0
HKD2_k127_6565646_3 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000009584 174.0
HKD2_k127_6567168_0 Collagenase K08303 - - 1.777e-286 897.0
HKD2_k127_6573738_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1502.0
HKD2_k127_6573738_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 327.0
HKD2_k127_6573738_2 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004204 269.0
HKD2_k127_6573738_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000004877 225.0
HKD2_k127_6573738_4 Outer membrane efflux protein - - - 0.00000000000000007471 93.0
HKD2_k127_6584656_0 - - - - 0.000000000000000000000000000000000000000000000001224 184.0
HKD2_k127_6584656_1 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000316 134.0
HKD2_k127_6588187_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 339.0
HKD2_k127_6588187_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000001024 83.0
HKD2_k127_6600593_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 573.0
HKD2_k127_6600593_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 403.0
HKD2_k127_6600593_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000006876 162.0
HKD2_k127_6600593_3 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.000000000000000000000000000000000001095 145.0
HKD2_k127_6600593_4 Protein of unknown function (DUF790) K09744 - - 0.00000000000000000000000000001648 127.0
HKD2_k127_6607640_0 SET domain K07117 - - 0.00000000000000000000004527 104.0
HKD2_k127_6607640_1 Bacterial alpha-L-rhamnosidase C-terminal domain K05989 - 3.2.1.40 0.00000003321 63.0
HKD2_k127_6607640_2 Carbohydrate family 9 binding domain-like - - - 0.0000004819 59.0
HKD2_k127_6607640_3 Cysteine-rich CPXCG - - - 0.000007753 57.0
HKD2_k127_6607640_5 Calcineurin-like phosphoesterase - - - 0.00001953 56.0
HKD2_k127_6608324_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 445.0
HKD2_k127_6608324_1 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000009449 98.0
HKD2_k127_6615070_0 Putative heavy-metal-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 336.0
HKD2_k127_6615070_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 297.0
HKD2_k127_6615070_2 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000008109 273.0
HKD2_k127_6615070_3 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000000000107 176.0
HKD2_k127_6615070_4 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000008094 170.0
HKD2_k127_6625895_0 Cation transporter/ATPase, N-terminus K01535 - 3.6.3.6 6.069e-220 710.0
HKD2_k127_6625895_1 COGs COG1252 NADH dehydrogenase FAD-containing subunit K17218 - 1.8.5.4 5.167e-207 653.0
HKD2_k127_6625895_10 domain, Protein K01447 - 3.5.1.28 0.000000000004975 79.0
HKD2_k127_6625895_11 AMP binding - GO:0008150,GO:0040007 - 0.00000008962 62.0
HKD2_k127_6625895_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000006561 56.0
HKD2_k127_6625895_13 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation K01691,K06252 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0007154,GO:0007165,GO:0007166,GO:0007224,GO:0007275,GO:0007399,GO:0008037,GO:0008038,GO:0008039,GO:0008150,GO:0008589,GO:0009966,GO:0009967,GO:0009987,GO:0010646,GO:0010647,GO:0022008,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0030182,GO:0031012,GO:0031647,GO:0032501,GO:0032502,GO:0044421,GO:0045880,GO:0048468,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050821,GO:0050896,GO:0051716,GO:0065007,GO:0065008 - 0.00002064 57.0
HKD2_k127_6625895_14 prohibitin homologues - - - 0.00007326 55.0
HKD2_k127_6625895_2 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 335.0
HKD2_k127_6625895_3 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000002557 276.0
HKD2_k127_6625895_4 self proteolysis - - - 0.000000000000000000000000000000000000000000007469 185.0
HKD2_k127_6625895_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000002112 169.0
HKD2_k127_6625895_6 Universal stress protein - - - 0.0000000000000000000000004165 109.0
HKD2_k127_6625895_7 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000001173 113.0
HKD2_k127_6625895_8 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000005369 109.0
HKD2_k127_6625895_9 AMP binding - GO:0008150,GO:0040007 - 0.0000000000000001054 87.0
HKD2_k127_6635715_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1107.0
HKD2_k127_6635715_1 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000000000000000000000000593 222.0
HKD2_k127_6637097_0 Peptidase family M1 domain K01256 - 3.4.11.2 5.794e-319 999.0
HKD2_k127_6637097_1 tRNA (guanine-N7-)-methyltransferase activity K03439,K18846 - 2.1.1.180,2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 467.0
HKD2_k127_6637097_2 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 434.0
HKD2_k127_6637097_3 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 338.0
HKD2_k127_6637097_4 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009088 267.0
HKD2_k127_6637097_5 Domain of unknown function (DUF1287) K09974 - - 0.00000000000000000000000000000000000000000000000000000000000000003694 230.0
HKD2_k127_6637097_7 Bacterial PH domain - - - 0.00000000000000000000000000001643 125.0
HKD2_k127_6637097_8 - - - - 0.0000000003311 63.0
HKD2_k127_6637097_9 - - - - 0.00000000109 69.0
HKD2_k127_6640270_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 484.0
HKD2_k127_6640270_1 PBS lyase HEAT-like repeat - - - 0.000006517 56.0
HKD2_k127_6644198_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 387.0
HKD2_k127_6644198_1 - - - - 0.000000000000000000000000000000000000000000000000000000672 204.0
HKD2_k127_6644198_2 - - - - 0.00000000000000000000000000000000000000000003857 179.0
HKD2_k127_6648080_0 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 471.0
HKD2_k127_6648080_1 glycine betaine K05845 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000142 279.0
HKD2_k127_6648080_2 ABC-type proline glycine betaine transport K05845,K05846 - - 0.0000000000000000000000000000000000000000000095 168.0
HKD2_k127_6653852_0 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 404.0
HKD2_k127_6653852_1 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 389.0
HKD2_k127_6653852_2 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000001611 232.0
HKD2_k127_6653852_3 PFAM amidohydrolase K20810 - 3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000002973 233.0
HKD2_k127_6653852_4 COGs COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000001729 210.0
HKD2_k127_6660982_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.823e-217 700.0
HKD2_k127_6660982_10 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000001985 166.0
HKD2_k127_6660982_12 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000000000000000000005856 102.0
HKD2_k127_6660982_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000006146 78.0
HKD2_k127_6660982_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000001112 64.0
HKD2_k127_6660982_17 PFAM regulatory protein, MarR - - - 0.00001841 53.0
HKD2_k127_6660982_2 amp-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 500.0
HKD2_k127_6660982_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 473.0
HKD2_k127_6660982_4 Lipase maturation factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007572 437.0
HKD2_k127_6660982_5 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 410.0
HKD2_k127_6660982_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 345.0
HKD2_k127_6660982_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000912 201.0
HKD2_k127_6660982_9 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000004849 160.0
HKD2_k127_6665940_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 415.0
HKD2_k127_6665940_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 356.0
HKD2_k127_6665940_2 Putative glycosyl hydrolase domain - - - 0.00000000000000000000006537 111.0
HKD2_k127_6665940_3 Copper binding proteins, plastocyanin/azurin family - - - 0.000003416 57.0
HKD2_k127_6668985_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 425.0
HKD2_k127_6668985_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 347.0
HKD2_k127_6668985_2 unsaturated fatty acid biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000915 286.0
HKD2_k127_6668985_3 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002336 241.0
HKD2_k127_6668985_4 Acetyltransferase (GNAT) domain K03817 - - 0.000000000000000000000000000000000000000000000000000000003322 205.0
HKD2_k127_6668985_5 Universal stress protein - - - 0.0000000000000000000000006841 110.0
HKD2_k127_6668985_7 Condensation domain - - - 0.00006404 56.0
HKD2_k127_6671346_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 514.0
HKD2_k127_6671346_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 533.0
HKD2_k127_6671346_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000008066 91.0
HKD2_k127_6671346_11 - - - - 0.0000000007257 68.0
HKD2_k127_6671346_12 PilZ domain - - - 0.00001194 56.0
HKD2_k127_6671346_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 502.0
HKD2_k127_6671346_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 383.0
HKD2_k127_6671346_4 EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 322.0
HKD2_k127_6671346_5 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 320.0
HKD2_k127_6671346_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003487 291.0
HKD2_k127_6671346_7 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000001347 230.0
HKD2_k127_6671346_8 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000001191 182.0
HKD2_k127_6671346_9 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000002986 143.0
HKD2_k127_6677003_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000009551 205.0
HKD2_k127_6677003_2 Calcineurin-like phosphoesterase - - - 0.00000000000000006491 91.0
HKD2_k127_6677003_3 PFAM ASPIC and UnbV - - - 0.0000000000000003728 87.0
HKD2_k127_6679385_0 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 522.0
HKD2_k127_6679385_1 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 390.0
HKD2_k127_6679385_2 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 332.0
HKD2_k127_6679385_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000004739 120.0
HKD2_k127_6679385_4 AAA domain K01551 - 3.6.3.16 0.000000000001075 70.0
HKD2_k127_6680411_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 464.0
HKD2_k127_6696167_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 5.046e-210 683.0
HKD2_k127_6696167_1 Belongs to the SEDS family K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 502.0
HKD2_k127_6696167_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000003238 156.0
HKD2_k127_6696167_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000004065 143.0
HKD2_k127_6696167_5 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000006937 140.0
HKD2_k127_6696167_6 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000006343 87.0
HKD2_k127_6702914_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 504.0
HKD2_k127_6702914_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000875 252.0
HKD2_k127_6704275_0 C-terminus of AA_permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 317.0
HKD2_k127_6704275_1 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005812 291.0
HKD2_k127_6707188_0 Sulfatase - - - 1.298e-208 681.0
HKD2_k127_6707188_1 PQQ enzyme repeat K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 437.0
HKD2_k127_6707188_2 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 341.0
HKD2_k127_6707188_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000003955 208.0
HKD2_k127_6707188_4 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000004735 198.0
HKD2_k127_6707188_5 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000006005 188.0
HKD2_k127_6707188_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000004381 172.0
HKD2_k127_6707541_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 537.0
HKD2_k127_6707541_1 Pyrrolo-quinoline quinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000208 297.0
HKD2_k127_6707541_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001591 246.0
HKD2_k127_6707541_3 FR47-like protein - - - 0.000000000000000000000000000000000000000000001226 171.0
HKD2_k127_6707541_4 Protein of unknown function (DUF4019) - - - 0.0000000000000000000000000000000644 141.0
HKD2_k127_6707541_5 cheY-homologous receiver domain - - - 0.0000000000000000001686 93.0
HKD2_k127_6707541_6 - - - - 0.000000000000000003959 96.0
HKD2_k127_6707774_0 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005177 286.0
HKD2_k127_6707774_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342,K10857 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006846 289.0
HKD2_k127_6707774_2 Glycosyl hydrolases family 43 - - - 0.000000000000000000006024 96.0
HKD2_k127_6707774_3 Glycosyl hydrolases family 43 - - - 0.00000006086 62.0
HKD2_k127_6712642_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 455.0
HKD2_k127_6712642_1 PilZ domain K02676 - - 0.0000000008418 59.0
HKD2_k127_6734440_0 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 458.0
HKD2_k127_6734440_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 381.0
HKD2_k127_6734440_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000006428 202.0
HKD2_k127_6734440_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000001049 176.0
HKD2_k127_6734440_4 - - - - 0.0000000000000000000000000000000003843 132.0
HKD2_k127_6734440_5 Putative bacterial sensory transduction regulator - - - 0.00000005086 61.0
HKD2_k127_6742512_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.125e-276 867.0
HKD2_k127_6742512_1 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 339.0
HKD2_k127_6742512_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 340.0
HKD2_k127_6742512_3 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009666 277.0
HKD2_k127_6742512_4 PFAM Fibronectin type III domain protein K05973 - 3.1.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000001854 267.0
HKD2_k127_6742512_5 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000001016 243.0
HKD2_k127_6742512_6 Domain of unknown function (DUF4132) - - - 0.00000000000000000000000000000000000000000000000005396 206.0
HKD2_k127_6742512_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000235 122.0
HKD2_k127_6742512_8 - - - - 0.00000000000000000758 87.0
HKD2_k127_6742512_9 - - - - 0.000000000000004375 88.0
HKD2_k127_674522_1 IgGFc binding protein - - - 0.0000000000002344 70.0
HKD2_k127_674522_2 23S rRNA-intervening sequence protein - - - 0.000008735 54.0
HKD2_k127_6745909_0 Transketolase, pyrimidine binding domain K11381,K21416 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 548.0
HKD2_k127_6745909_1 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 359.0
HKD2_k127_6745909_2 peptidase K19304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009291 287.0
HKD2_k127_6745909_3 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000415 134.0
HKD2_k127_6745909_4 Radical SAM superfamily - - - 0.00000000000000000000000492 117.0
HKD2_k127_6745909_5 Alpha/beta hydrolase family - - - 0.00000000000001885 83.0
HKD2_k127_6745909_6 Bacterial regulatory proteins, tetR family - - - 0.00000000088 67.0
HKD2_k127_6745990_0 Multicopper oxidase K20219 - 1.10.3.4 0.00000000000000000000000000000000000000000000000000000000001694 219.0
HKD2_k127_6746089_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 415.0
HKD2_k127_6746089_1 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 389.0
HKD2_k127_6746089_10 Prokaryotic N-terminal methylation motif K02458 - - 0.000108 48.0
HKD2_k127_6746089_2 Type IV pilus assembly protein PilM; K02461 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 381.0
HKD2_k127_6746089_3 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 311.0
HKD2_k127_6746089_4 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004659 284.0
HKD2_k127_6746089_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009125 260.0
HKD2_k127_6746089_6 BtpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000001993 250.0
HKD2_k127_6746089_7 Type II secretion system (T2SS), protein J K02459 - - 0.00000000000000000000000000000000000000000000000000000000000002618 226.0
HKD2_k127_6746089_9 Heat shock 70 kDa protein K04043 - - 0.000000000000003387 86.0
HKD2_k127_6758108_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.176e-220 690.0
HKD2_k127_6758108_1 cheY-homologous receiver domain - - - 0.000000000000000000000001817 109.0
HKD2_k127_6758108_2 - - - - 0.000003356 49.0
HKD2_k127_6760984_1 Protein of unknown function (DUF533) K06596 - - 0.0000000000000000000000000004711 120.0
HKD2_k127_6762061_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 416.0
HKD2_k127_6762061_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 362.0
HKD2_k127_6762061_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 348.0
HKD2_k127_6762061_3 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001401 258.0
HKD2_k127_6764963_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 420.0
HKD2_k127_6764963_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000005867 110.0
HKD2_k127_6764963_2 Protein of unknown function, DUF255 - - - 0.000000003109 62.0
HKD2_k127_6764963_3 amine dehydrogenase activity - - - 0.00009805 55.0
HKD2_k127_6764963_4 - - - - 0.0002543 44.0
HKD2_k127_677393_0 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 328.0
HKD2_k127_677393_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620,K00930 - 2.3.1.1,2.3.1.35,2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 288.0
HKD2_k127_677393_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000004885 258.0
HKD2_k127_677393_3 cell envelope organization K05807,K08309 - - 0.000000000000000119 95.0
HKD2_k127_680516_0 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 334.0
HKD2_k127_680516_1 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000369 243.0
HKD2_k127_680516_2 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000003876 171.0
HKD2_k127_680516_3 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000004499 104.0
HKD2_k127_680516_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0001721 52.0
HKD2_k127_680516_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000666 50.0
HKD2_k127_6808306_0 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 354.0
HKD2_k127_6808306_1 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 316.0
HKD2_k127_6808306_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000185 137.0
HKD2_k127_6810853_0 Aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 478.0
HKD2_k127_6810853_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000513 201.0
HKD2_k127_6810853_2 Alpha/beta hydrolase family K06999 - - 0.00000000000000000000000000002262 120.0
HKD2_k127_6810930_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 472.0
HKD2_k127_6810930_1 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 361.0
HKD2_k127_6816116_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 410.0
HKD2_k127_6816116_1 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 353.0
HKD2_k127_6816116_2 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001382 269.0
HKD2_k127_6816116_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000001403 269.0
HKD2_k127_6816116_4 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000001426 252.0
HKD2_k127_6816116_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000013 140.0
HKD2_k127_6816116_6 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000006594 131.0
HKD2_k127_6816116_8 MacB-like periplasmic core domain K02004 - - 0.000009793 48.0
HKD2_k127_6816116_9 Trypsin-like serine protease - - - 0.0001256 53.0
HKD2_k127_6816245_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 428.0
HKD2_k127_6816245_1 ABC transporter, ATP-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 409.0
HKD2_k127_6816245_10 transcriptional regulator - - - 0.00000000000111 76.0
HKD2_k127_6816245_2 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 359.0
HKD2_k127_6816245_3 Heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 341.0
HKD2_k127_6816245_4 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 304.0
HKD2_k127_6816245_5 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 312.0
HKD2_k127_6816245_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000001055 251.0
HKD2_k127_6816245_7 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000003339 209.0
HKD2_k127_6816245_8 - - - - 0.000000000000000000000000000000000000006271 155.0
HKD2_k127_6816245_9 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.00000000000000000000003473 100.0
HKD2_k127_6834575_0 Histidine kinase - - - 0.0 1394.0
HKD2_k127_6834575_1 ABC transporter K06147,K06148 - - 7.153e-231 728.0
HKD2_k127_6834575_11 Lycopene cyclase protein - - - 0.000000000000000000000000000000000000000000002626 181.0
HKD2_k127_6834575_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000004418 166.0
HKD2_k127_6834575_13 Domain present in phytochromes and cGMP-specific phosphodiesterases. K07636 - 2.7.13.3 0.000000000000000000000000000000000000006741 160.0
HKD2_k127_6834575_14 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000004781 143.0
HKD2_k127_6834575_16 Protein of unknown function (DUF1109) - - - 0.000000000000004812 83.0
HKD2_k127_6834575_17 Cytochrome c oxidase subunit K00376 - 1.7.2.4 0.0000000000002244 70.0
HKD2_k127_6834575_18 Belongs to the peptidase M12A family K08076 - 3.4.24.21 0.0000000000002401 83.0
HKD2_k127_6834575_2 Bacterial regulatory protein, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 475.0
HKD2_k127_6834575_20 PAS fold - - - 0.0000000001199 73.0
HKD2_k127_6834575_3 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 324.0
HKD2_k127_6834575_4 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 328.0
HKD2_k127_6834575_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000515 278.0
HKD2_k127_6834575_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001923 256.0
HKD2_k127_6834575_7 lysozyme activity K07260 - 3.4.17.14 0.00000000000000000000000000000000000000000000000000000000000000000533 246.0
HKD2_k127_6834575_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000009781 225.0
HKD2_k127_6837201_0 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 4.249e-222 703.0
HKD2_k127_6837201_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 299.0
HKD2_k127_6837201_2 Alpha beta hydrolase K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004641 252.0
HKD2_k127_6837201_4 Glycosyl transferase family 2 - - - 0.00000000000000000003248 90.0
HKD2_k127_6844048_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 409.0
HKD2_k127_6844048_1 ABC transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002163 289.0
HKD2_k127_6844048_2 FMN reductase (NADPH) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005329 253.0
HKD2_k127_6844048_3 - - - - 0.000000000000000000000000000000000000000000000000000000006661 217.0
HKD2_k127_687209_0 Diacylglycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000000002063 198.0
HKD2_k127_687209_1 Protein of unknown function (DUF1298) - - - 0.0000000000000000000002708 111.0
HKD2_k127_6878464_0 nodulation K00612 - - 7.341e-230 733.0
HKD2_k127_6878464_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 463.0
HKD2_k127_6878464_10 - - - - 0.00000000000001588 87.0
HKD2_k127_6878464_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000001277 71.0
HKD2_k127_6878464_12 Methyltransferase - - - 0.000000008659 66.0
HKD2_k127_6878464_13 - - - - 0.00000003899 57.0
HKD2_k127_6878464_14 GDSL-like Lipase/Acylhydrolase family - - - 0.000000495 62.0
HKD2_k127_6878464_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 366.0
HKD2_k127_6878464_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001131 282.0
HKD2_k127_6878464_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005442 269.0
HKD2_k127_6878464_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000001677 267.0
HKD2_k127_6878464_6 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000002976 265.0
HKD2_k127_6878464_7 - - - - 0.0000000000000000000000000000000001839 153.0
HKD2_k127_6878464_8 cell envelope organization K05807,K08309 - - 0.00000000000000000000000000000005678 145.0
HKD2_k127_6878464_9 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000003619 129.0
HKD2_k127_6899575_0 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 497.0
HKD2_k127_6899575_1 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 382.0
HKD2_k127_6899575_10 membrane K00389 - - 0.0000000000000001794 83.0
HKD2_k127_6899575_11 Protein of unknown function (DUF2892) - - - 0.0000000000000002199 88.0
HKD2_k127_6899575_12 - - - - 0.000000000001289 73.0
HKD2_k127_6899575_13 FecR protein - - - 0.000000007142 68.0
HKD2_k127_6899575_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 362.0
HKD2_k127_6899575_3 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000008504 221.0
HKD2_k127_6899575_4 Putative zinc-finger K03088 - - 0.0000000000000000000000000000000000000000000000000000001348 203.0
HKD2_k127_6899575_5 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000003296 162.0
HKD2_k127_6899575_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000001034 154.0
HKD2_k127_6899575_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000009417 139.0
HKD2_k127_6899575_8 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000001271 115.0
HKD2_k127_6899575_9 AMP binding - GO:0008150,GO:0040007 - 0.00000000000000004342 87.0
HKD2_k127_6902523_0 AcrB/AcrD/AcrF family - - - 2.463e-258 823.0
HKD2_k127_6910266_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 417.0
HKD2_k127_6910266_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000002484 196.0
HKD2_k127_6910266_2 Met-10+ like-protein - - - 0.0000000000000000000000000000000000000004338 168.0
HKD2_k127_6910266_3 OsmC-like protein - - - 0.00000000000000000000000000000000008571 137.0
HKD2_k127_6910266_4 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000001323 144.0
HKD2_k127_6910266_5 Domain of unknown function DUF302 - - - 0.000000000000000000000000000003995 128.0
HKD2_k127_6910266_7 PFAM Sodium Bile acid symporter family K03325 - - 0.000000000000000001087 93.0
HKD2_k127_6916557_0 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 389.0
HKD2_k127_6916557_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 359.0
HKD2_k127_6916557_2 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000002165 211.0
HKD2_k127_6916557_3 PFAM CHAD domain containing protein - - - 0.0000000000000000000000006413 121.0
HKD2_k127_6916557_4 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.00003936 56.0
HKD2_k127_6950154_0 thiamine pyrophosphate protein TPP binding domain protein K00156,K01652 - 1.2.5.1,2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 432.0
HKD2_k127_6950154_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 420.0
HKD2_k127_6950154_10 Transcriptional regulatory protein, C terminal K02483 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00001613 51.0
HKD2_k127_6950154_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000006141 164.0
HKD2_k127_6950154_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000003145 137.0
HKD2_k127_6950154_4 Methyltransferase domain - - - 0.000000000000000000002603 102.0
HKD2_k127_6950154_5 Flotillin - - - 0.0000000000004801 72.0
HKD2_k127_6950154_6 cellular response to DNA damage stimulus - GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.000000003505 66.0
HKD2_k127_6950154_7 COG0671 Membrane-associated phospholipid phosphatase - - - 0.0000003881 62.0
HKD2_k127_6950154_8 PFAM Citrate K01647 - 2.3.3.1 0.0000004862 60.0
HKD2_k127_6950154_9 transcriptional regulator - - - 0.000001518 56.0
HKD2_k127_6976272_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 393.0
HKD2_k127_6976272_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000003056 178.0
HKD2_k127_6976272_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000008692 145.0
HKD2_k127_6976272_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000376 96.0
HKD2_k127_6976272_4 Putative metal-binding motif - - - 0.0000000000000001116 95.0
HKD2_k127_6982606_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003005 247.0
HKD2_k127_6982606_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000006027 232.0
HKD2_k127_6982606_2 histidine kinase A domain protein - - - 0.0000000000000000000001124 113.0
HKD2_k127_6998582_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 370.0
HKD2_k127_6999370_0 Flavin-binding monooxygenase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 519.0
HKD2_k127_6999370_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 437.0
HKD2_k127_6999370_2 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001449 280.0
HKD2_k127_6999370_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003265 260.0
HKD2_k127_6999370_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000001599 146.0
HKD2_k127_6999370_5 GON domain - - - 0.0000000000000000000000000000000002291 138.0
HKD2_k127_6999370_6 Uncharacterized conserved protein (DUF2304) K09153 - - 0.000000008018 62.0
HKD2_k127_6999742_0 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 410.0
HKD2_k127_6999742_1 alpha beta - - - 0.000000000000000000000000000000000000000000000001457 196.0
HKD2_k127_6999742_2 glycoside hydrolase, family K07273 - - 0.000000000000000000000000000000000000000000001543 178.0
HKD2_k127_6999742_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.00000000000000000000000001646 120.0
HKD2_k127_700378_0 GGDEF domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 429.0
HKD2_k127_700378_1 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 340.0
HKD2_k127_7004066_0 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000007253 160.0
HKD2_k127_7004066_1 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000001064 117.0
HKD2_k127_7004066_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000008409 101.0
HKD2_k127_7006676_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 381.0
HKD2_k127_7006676_1 Domain of unknown function (DUF4272) - - - 0.0000000000000000000000000000000000000002966 158.0
HKD2_k127_7006676_2 - - - - 0.0000000000000000000000000000005892 128.0
HKD2_k127_7022391_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 292.0
HKD2_k127_7022391_1 Thioredoxin-like - - - 0.0000000000000000000000000000000000121 152.0
HKD2_k127_7025553_0 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 316.0
HKD2_k127_7049780_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000002056 191.0
HKD2_k127_7049780_2 Transcriptional regulator, CarD family K07736 - - 0.00000000000000007327 87.0
HKD2_k127_708699_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 329.0
HKD2_k127_7095935_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 305.0
HKD2_k127_7095935_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 310.0
HKD2_k127_7106802_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 7.849e-281 881.0
HKD2_k127_7125433_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004264 234.0
HKD2_k127_7125433_1 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000002004 228.0
HKD2_k127_7125433_10 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000002803 68.0
HKD2_k127_7125433_12 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000006961 61.0
HKD2_k127_7125433_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000006311 187.0
HKD2_k127_7125433_3 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000000003407 165.0
HKD2_k127_7125433_4 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.0000000000000000000000000000000000004553 152.0
HKD2_k127_7125433_5 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000004289 141.0
HKD2_k127_7125433_6 PAP2 superfamily C-terminal - - - 0.0000000000000000000000000000016 132.0
HKD2_k127_7125433_7 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.000000000000000000000000000002233 126.0
HKD2_k127_7125433_8 Cytochrome c - - - 0.0000000000000000000000000002217 119.0
HKD2_k127_7125433_9 Hemerythrin HHE cation binding domain - - - 0.000000000000000000009362 101.0
HKD2_k127_7134492_0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 625.0
HKD2_k127_7134492_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 635.0
HKD2_k127_7134492_10 Chorismate mutase type II K14187 - 1.3.1.12,5.4.99.5 0.0000000000000000000000000000000000000000000000000002228 201.0
HKD2_k127_7134492_11 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000000000000000000000000000009524 171.0
HKD2_k127_7134492_12 metal cluster binding - - - 0.00000000000000000000000000000000000000000002258 169.0
HKD2_k127_7134492_13 phospholipase C - - - 0.000000000000000000000000000000005043 143.0
HKD2_k127_7134492_15 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000003113 111.0
HKD2_k127_7134492_16 Glutamine amidotransferases class-II - - - 0.000000000000000000002244 104.0
HKD2_k127_7134492_2 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 541.0
HKD2_k127_7134492_3 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 523.0
HKD2_k127_7134492_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 520.0
HKD2_k127_7134492_5 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 396.0
HKD2_k127_7134492_6 Carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 351.0
HKD2_k127_7134492_7 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 336.0
HKD2_k127_7134492_8 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000001447 228.0
HKD2_k127_7134492_9 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000001667 220.0
HKD2_k127_7145031_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 6.397e-308 967.0
HKD2_k127_7145031_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 471.0
HKD2_k127_7145031_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 297.0
HKD2_k127_7145031_3 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002144 271.0
HKD2_k127_7145031_4 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001787 266.0
HKD2_k127_7155002_0 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007427 266.0
HKD2_k127_7155002_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000894 208.0
HKD2_k127_7192680_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.154e-228 717.0
HKD2_k127_7192680_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 566.0
HKD2_k127_7192680_2 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009067 430.0
HKD2_k127_7192680_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 342.0
HKD2_k127_7192680_4 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000594 276.0
HKD2_k127_7192680_5 - - - - 0.000000000000000000000000008339 119.0
HKD2_k127_7192680_6 MerR HTH family regulatory protein - - - 0.000000000000000000000000841 107.0
HKD2_k127_7192680_7 COG COG2755 Lysophospholipase L1 and related esterases - - - 0.00000000007246 70.0
HKD2_k127_719270_0 domain protein K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 550.0
HKD2_k127_719270_1 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 317.0
HKD2_k127_7247798_0 methyltransferase - - - 0.000000000000000000000000000000003777 136.0
HKD2_k127_7247798_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0002651 49.0
HKD2_k127_7251382_0 Histidine biosynthesis protein K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 334.0
HKD2_k127_7251382_2 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000001447 220.0
HKD2_k127_7251382_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000114 142.0
HKD2_k127_7251382_4 Protein of unknown function (DUF533) K11962 - - 0.0000000000000000000000000000004404 126.0
HKD2_k127_7254183_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 2.119e-200 651.0
HKD2_k127_7254183_1 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 474.0
HKD2_k127_7254183_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 321.0
HKD2_k127_7254183_3 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000000000000000000000000000000001589 223.0
HKD2_k127_7274102_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003601 288.0
HKD2_k127_7288291_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 1.225e-234 737.0
HKD2_k127_7288291_2 Stringent starvation protein B K03600 - - 0.0000000000000000000000000000002589 129.0
HKD2_k127_7309521_1 Putative esterase - - - 0.00000000000000000000000000000000000000000000001038 191.0
HKD2_k127_7321856_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 533.0
HKD2_k127_7321856_1 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 457.0
HKD2_k127_7321856_2 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000005317 228.0
HKD2_k127_7321856_3 YjbR - - - 0.0000000000000000000000000000002218 133.0
HKD2_k127_7321856_4 PFAM regulatory protein, MarR - - - 0.0007889 49.0
HKD2_k127_732467_0 Pfam Major Facilitator Superfamily - - - 1.569e-202 641.0
HKD2_k127_732467_1 FAD dependent oxidoreductase K09879 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 362.0
HKD2_k127_732467_2 PFAM Rhodanese domain protein K03892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001053 272.0
HKD2_k127_732467_3 Conserved TM helix - - - 0.000000000000002329 86.0
HKD2_k127_732467_4 FAD dependent oxidoreductase K09879 - - 0.00000525 50.0
HKD2_k127_738809_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000001948 222.0
HKD2_k127_738809_1 Belongs to the glycosyl hydrolase 1 family - - - 0.000000000000000000000000000000000000000006344 156.0
HKD2_k127_7391177_0 Family membership - - - 0.0 1041.0
HKD2_k127_7391177_1 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 571.0
HKD2_k127_7391177_10 Oxygen-binding protein. May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes. The oxygen- binding site contains two iron atoms K07216 - - 0.0008134 46.0
HKD2_k127_7391177_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 328.0
HKD2_k127_7391177_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000001738 247.0
HKD2_k127_7391177_4 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000005682 214.0
HKD2_k127_7391177_5 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000007174 184.0
HKD2_k127_7391177_6 - - - - 0.000000000000000000000000000000000000000000000624 186.0
HKD2_k127_7391177_7 - - - - 0.00000000000000000000000000000002356 141.0
HKD2_k127_7391177_8 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000001336 100.0
HKD2_k127_7391177_9 - - - - 0.00000000007234 74.0
HKD2_k127_739349_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 402.0
HKD2_k127_739349_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 387.0
HKD2_k127_739349_2 PilT protein domain protein - - - 0.00000000000000000000000000000000000000006105 163.0
HKD2_k127_739349_3 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000004758 162.0
HKD2_k127_739349_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000003986 100.0
HKD2_k127_739349_5 Pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0000000000001466 81.0
HKD2_k127_7399662_0 protein kinase activity - - - 0.0 1161.0
HKD2_k127_7399662_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005752 250.0
HKD2_k127_7399662_2 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000005266 233.0
HKD2_k127_7399662_5 Protein of unknown function (DUF533) - - - 0.0004643 49.0
HKD2_k127_74472_0 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 457.0
HKD2_k127_74472_1 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 300.0
HKD2_k127_74472_2 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000006081 282.0
HKD2_k127_74472_3 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000001912 101.0
HKD2_k127_74472_5 domain protein - - - 0.0000004963 61.0
HKD2_k127_747195_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 567.0
HKD2_k127_747195_1 phosphorelay signal transduction system K10941,K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 470.0
HKD2_k127_747195_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 348.0
HKD2_k127_747195_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000002016 217.0
HKD2_k127_747195_4 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.0000000000000000000000000000000000005355 158.0
HKD2_k127_747195_5 Protein of unknown function (DUF1156) - - - 0.000000000000000000009683 100.0
HKD2_k127_747195_6 Fibronectin type 3 domain - - - 0.000000000000002061 91.0
HKD2_k127_7477188_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 364.0
HKD2_k127_7477188_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004458 277.0
HKD2_k127_7477188_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000282 98.0
HKD2_k127_748050_0 Domain of unknown function (DUF4132) - - - 2.845e-220 728.0
HKD2_k127_748050_1 COG0714 MoxR-like ATPases - - - 0.000000000000002767 77.0
HKD2_k127_748619_0 Family membership - - - 5.724e-219 737.0
HKD2_k127_748619_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000005344 237.0
HKD2_k127_748619_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000181 124.0
HKD2_k127_748619_3 oligosaccharyl transferase activity - - - 0.0000000000000000000000001702 111.0
HKD2_k127_7522623_0 Protein of unknown function (DUF790) K09744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005956 289.0
HKD2_k127_7522623_1 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001219 261.0
HKD2_k127_7540356_0 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 326.0
HKD2_k127_7540356_1 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001087 265.0
HKD2_k127_7540356_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000378 208.0
HKD2_k127_7540356_3 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.00000000000000000000009562 108.0
HKD2_k127_7567099_0 MMPL family K07003 - - 5.803e-273 884.0
HKD2_k127_7567099_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 367.0
HKD2_k127_7567099_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000122 299.0
HKD2_k127_7567099_3 Glycosyltransferase Family 4 K14335 - - 0.0000000000000000000000000000000000000000000000002471 188.0
HKD2_k127_7567099_4 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.0000000000000000000000000000553 124.0
HKD2_k127_7567099_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00001492 59.0
HKD2_k127_7569372_0 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000001287 164.0
HKD2_k127_7569372_1 serine threonine protein kinase - - - 0.00000000000000000000000000000000002656 156.0
HKD2_k127_7569372_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K14331 - 4.1.99.5 0.000002063 62.0
HKD2_k127_7604401_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 2.956e-234 751.0
HKD2_k127_7604401_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 347.0
HKD2_k127_7604401_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000001923 171.0
HKD2_k127_7604401_3 HEAT repeat - - - 0.00000000000000000000000000000000000000000000005045 192.0
HKD2_k127_7604401_4 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000006592 153.0
HKD2_k127_7604401_5 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000004069 153.0
HKD2_k127_7604401_6 Chemotaxis protein CheY K03413 - - 0.000000000000000000000000000000001426 138.0
HKD2_k127_7604401_7 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000005266 106.0
HKD2_k127_76160_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 567.0
HKD2_k127_76160_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000002098 121.0
HKD2_k127_76160_2 diguanylate cyclase - - - 0.000000000000000002154 101.0
HKD2_k127_76160_3 lipase activity K15349 - - 0.00000009154 64.0
HKD2_k127_76160_4 alpha beta - - - 0.0000003655 63.0
HKD2_k127_7622897_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 372.0
HKD2_k127_7622897_1 metallopeptidase activity - - - 0.000000000000000000000000000000002822 135.0
HKD2_k127_7622897_2 EamA-like transporter family - - - 0.00000000000000004948 92.0
HKD2_k127_76275_0 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 526.0
HKD2_k127_76275_1 Domain of unknown function (DUF362) - - - 0.00000000000000000008102 101.0
HKD2_k127_76275_2 MatE - - - 0.000000000000000001148 100.0
HKD2_k127_7647303_0 Short-chain dehydrogenase reductase sdr K21883 - 1.1.1.401 0.0000000000000000000000000000000000000000000000000000000000000000000000000000312 270.0
HKD2_k127_7649081_0 Type II/IV secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 568.0
HKD2_k127_7667937_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000001005 184.0
HKD2_k127_7669210_0 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 617.0
HKD2_k127_7669210_1 Thioesterase-like superfamily K01075 - 3.1.2.23 0.00000000000000000000000000000000000002067 147.0
HKD2_k127_7670831_0 Family membership - - - 1.738e-282 906.0
HKD2_k127_7670831_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000463 249.0
HKD2_k127_7670831_2 Alkaline phosphatase with broad substrate specificity K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000003779 229.0
HKD2_k127_7676649_0 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 403.0
HKD2_k127_7676649_1 Protein of unknown function (DUF1595) - - - 0.00000000000000000000000000005749 130.0
HKD2_k127_7676649_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000899 100.0
HKD2_k127_7684616_0 Major facilitator Superfamily K16210 - - 0.00000000000000000000000000000000000000000000000000000000000000000001742 250.0
HKD2_k127_7684616_1 - - - - 0.00000000000000000000000000000000000000000000000000000000003618 229.0
HKD2_k127_7684616_2 COG2771 DNA-binding HTH domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000001153 196.0
HKD2_k127_7684616_3 - - - - 0.00000000000000000000000000000000000000000000000000002383 199.0
HKD2_k127_7684616_4 Peptidase family M48 - - - 0.000000000000157 82.0
HKD2_k127_7685785_0 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 3.677e-280 883.0
HKD2_k127_7685785_1 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 475.0
HKD2_k127_7685785_10 Baseplate J-like protein - - - 0.00000000006122 74.0
HKD2_k127_7685785_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 336.0
HKD2_k127_7685785_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000000000001054 205.0
HKD2_k127_7685785_4 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000003078 190.0
HKD2_k127_7685785_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000705 168.0
HKD2_k127_7685785_6 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000002575 132.0
HKD2_k127_7685785_7 Protein of unknown function (DUF1109) - - - 0.000000000000000000000001276 113.0
HKD2_k127_7685785_8 Matrixin - - - 0.0000000000000000005067 101.0
HKD2_k127_7685785_9 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000144 88.0
HKD2_k127_7690372_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 478.0
HKD2_k127_7690372_1 RmlD substrate binding domain K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 417.0
HKD2_k127_7690372_2 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 315.0
HKD2_k127_7690372_3 - - - - 0.00000000000000000000000000000000000001553 148.0
HKD2_k127_7693059_0 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 319.0
HKD2_k127_7693059_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007567 289.0
HKD2_k127_7693059_2 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004083 278.0
HKD2_k127_7693059_3 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006764 272.0
HKD2_k127_7693059_4 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000001482 239.0
HKD2_k127_7693059_5 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000000005044 200.0
HKD2_k127_7693059_6 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000002879 155.0
HKD2_k127_7693059_7 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000003157 161.0
HKD2_k127_7693059_8 Transporter associated domain K06189 - - 0.00000000000000000000000000000000001952 139.0
HKD2_k127_7693059_9 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000009691 130.0
HKD2_k127_7700433_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 504.0
HKD2_k127_7700433_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 409.0
HKD2_k127_7700433_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 389.0
HKD2_k127_7700433_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000005114 278.0
HKD2_k127_7700433_4 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007255 252.0
HKD2_k127_7700433_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000008416 214.0
HKD2_k127_7700433_6 - - - - 0.000000000000000000000000000000000000002947 166.0
HKD2_k127_7711668_0 Aminotransferase K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 607.0
HKD2_k127_7711668_1 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 403.0
HKD2_k127_7711668_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007405 377.0
HKD2_k127_7711668_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003099 237.0
HKD2_k127_7711668_4 Bacterial SH3 domain homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000207 229.0
HKD2_k127_7711668_5 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000002478 200.0
HKD2_k127_7711668_6 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000001197 124.0
HKD2_k127_7711668_7 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000002289 61.0
HKD2_k127_7711668_9 His Kinase A (phosphoacceptor) domain - - - 0.0001589 49.0
HKD2_k127_7712526_0 DNA methylase K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 382.0
HKD2_k127_7712526_1 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007028 274.0
HKD2_k127_7712526_2 RelA SpoT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001183 282.0
HKD2_k127_7712526_3 MMPL family K06994 - - 0.000000000000000000000000000000000000000006647 156.0
HKD2_k127_7712526_4 - - - - 0.0003092 53.0
HKD2_k127_7719771_0 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003119 254.0
HKD2_k127_7719771_1 glucan 1,4-alpha-glucosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001489 240.0
HKD2_k127_7721953_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1088.0
HKD2_k127_7721953_1 Required for chromosome condensation and partitioning K03529 - - 1.459e-219 725.0
HKD2_k127_7721953_10 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000009097 257.0
HKD2_k127_7721953_11 lipid kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008666 248.0
HKD2_k127_7721953_12 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000258 221.0
HKD2_k127_7721953_13 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000005351 199.0
HKD2_k127_7721953_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000001898 190.0
HKD2_k127_7721953_16 EAL domain - - - 0.000000000000000000000000000000001663 139.0
HKD2_k127_7721953_17 protein conserved in bacteria - - - 0.000000000000000003183 87.0
HKD2_k127_7721953_18 FHA domain - - - 0.00000000000003677 84.0
HKD2_k127_7721953_2 Transcriptional regulator K03655,K10439,K11708 - 3.6.4.12 2.779e-202 644.0
HKD2_k127_7721953_20 High potential iron-sulfur protein - - - 0.000000000216 72.0
HKD2_k127_7721953_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008489 530.0
HKD2_k127_7721953_4 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 539.0
HKD2_k127_7721953_5 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 380.0
HKD2_k127_7721953_6 PFAM asparagine synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 360.0
HKD2_k127_7721953_7 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 346.0
HKD2_k127_7721953_8 geranylgeranyl reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 350.0
HKD2_k127_7721953_9 Dna alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002246 248.0
HKD2_k127_7729493_0 FAD-binding domain K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 499.0
HKD2_k127_7729493_1 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 314.0
HKD2_k127_7729493_2 Oxygen tolerance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001164 274.0
HKD2_k127_7729493_3 Fatty acid desaturase K00508 GO:0001676,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016213,GO:0016215,GO:0016491,GO:0016705,GO:0016717,GO:0019752,GO:0032787,GO:0042759,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:0072330,GO:1901576 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000004648 230.0
HKD2_k127_7729493_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000002532 202.0
HKD2_k127_7729493_7 heat shock protein binding - - - 0.00000000000001587 82.0
HKD2_k127_772974_0 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 430.0
HKD2_k127_772974_1 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 317.0
HKD2_k127_7735776_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 2.093e-241 764.0
HKD2_k127_7735776_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 538.0
HKD2_k127_7735776_2 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000005293 270.0
HKD2_k127_7735776_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004155 259.0
HKD2_k127_7735776_5 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.000000000000000000000003624 116.0
HKD2_k127_7737819_0 Family membership - - - 2.717e-274 890.0
HKD2_k127_7737819_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 2.601e-263 828.0
HKD2_k127_7737819_10 Two component signalling adaptor domain K03408 - - 0.000000003721 66.0
HKD2_k127_7737819_11 CheW-like domain K03408 - - 0.00000001839 62.0
HKD2_k127_7737819_2 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 484.0
HKD2_k127_7737819_3 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 354.0
HKD2_k127_7737819_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000003091 244.0
HKD2_k127_7737819_5 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000002237 242.0
HKD2_k127_7737819_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000002058 185.0
HKD2_k127_7737819_7 Methyl-transferase K00575 - 2.1.1.80 0.00000000000000000000000000000000000001468 159.0
HKD2_k127_7737819_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000002767 145.0
HKD2_k127_7737819_9 Transcriptional regulator K07775 - - 0.000000000000000337 83.0
HKD2_k127_7739470_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 559.0
HKD2_k127_7739470_1 epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 407.0
HKD2_k127_7739470_10 PFAM CBS domain containing protein K04767 - - 0.0000000000002507 76.0
HKD2_k127_7739470_12 - - - - 0.000000004298 69.0
HKD2_k127_7739470_13 High confidence in function and specificity - - - 0.000000005712 57.0
HKD2_k127_7739470_2 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 410.0
HKD2_k127_7739470_3 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 336.0
HKD2_k127_7739470_4 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 310.0
HKD2_k127_7739470_5 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000004902 207.0
HKD2_k127_7739470_6 Domain of unknown function (DUF4398) - - - 0.0000000000000000000000000000000000000000000000000009277 199.0
HKD2_k127_7739470_7 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000008667 133.0
HKD2_k127_7739470_8 Domain of unknown function (DUF4398) - - - 0.000000000000000005154 92.0
HKD2_k127_7739470_9 cheY-homologous receiver domain - - - 0.00000000000000000823 91.0
HKD2_k127_7763170_0 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 390.0
HKD2_k127_7763170_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009122 272.0
HKD2_k127_7763170_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001955 250.0
HKD2_k127_7763170_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000005591 155.0
HKD2_k127_7763494_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 609.0
HKD2_k127_7763494_1 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 314.0
HKD2_k127_7763494_2 Cupin domain - - - 0.000000000000000000000000000000000000002586 155.0
HKD2_k127_7764241_0 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 494.0
HKD2_k127_7764241_1 Gaf domain - - - 0.0000000000000000000000000000001309 144.0
HKD2_k127_7769389_0 Xanthine dehydrogenase K00106,K00157 GO:0000166,GO:0000302,GO:0001932,GO:0001933,GO:0001934,GO:0001936,GO:0001937,GO:0002197,GO:0002237,GO:0003674,GO:0003824,GO:0004031,GO:0004854,GO:0004855,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005783,GO:0005829,GO:0006082,GO:0006139,GO:0006144,GO:0006145,GO:0006150,GO:0006163,GO:0006195,GO:0006206,GO:0006520,GO:0006525,GO:0006568,GO:0006576,GO:0006586,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006919,GO:0006950,GO:0006979,GO:0007275,GO:0007568,GO:0007589,GO:0007595,GO:0008150,GO:0008152,GO:0008285,GO:0008340,GO:0009056,GO:0009058,GO:0009064,GO:0009072,GO:0009112,GO:0009114,GO:0009115,GO:0009117,GO:0009166,GO:0009266,GO:0009308,GO:0009408,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009636,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010044,GO:0010259,GO:0010468,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012505,GO:0016491,GO:0016528,GO:0016529,GO:0016623,GO:0016661,GO:0016662,GO:0016725,GO:0016726,GO:0016727,GO:0016903,GO:0017144,GO:0018130,GO:0019220,GO:0019222,GO:0019438,GO:0019439,GO:0019637,GO:0019752,GO:0022603,GO:0023051,GO:0023056,GO:0023057,GO:0030151,GO:0030162,GO:0030856,GO:0030857,GO:0030879,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032268,GO:0032269,GO:0032270,GO:0032496,GO:0032501,GO:0032502,GO:0032872,GO:0032874,GO:0032991,GO:0033993,GO:0034097,GO:0034404,GO:0034418,GO:0034465,GO:0034612,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042127,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042430,GO:0042493,GO:0042542,GO:0042579,GO:0042802,GO:0042803,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043167,GO:0043168,GO:0043169,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043280,GO:0043281,GO:0043408,GO:0043410,GO:0043436,GO:0043473,GO:0043546,GO:0044093,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045471,GO:0045595,GO:0045596,GO:0045601,GO:0045602,GO:0045862,GO:0045936,GO:0045937,GO:0046100,GO:0046110,GO:0046113,GO:0046415,GO:0046434,GO:0046483,GO:0046486,GO:0046677,GO:0046700,GO:0046872,GO:0046903,GO:0046914,GO:0046983,GO:0048037,GO:0048066,GO:0048069,GO:0048072,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048731,GO:0048732,GO:0048856,GO:0050250,GO:0050421,GO:0050660,GO:0050662,GO:0050678,GO:0050680,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050878,GO:0050896,GO:0051093,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051336,GO:0051345,GO:0051536,GO:0051537,GO:0051540,GO:0051704,GO:0051707,GO:0051716,GO:0051896,GO:0051898,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070302,GO:0070304,GO:0070555,GO:0070674,GO:0070887,GO:0071310,GO:0071345,GO:0071347,GO:0071356,GO:0071704,GO:0071949,GO:0072521,GO:0072522,GO:0072523,GO:0072527,GO:0080090,GO:0080134,GO:0080135,GO:0090287,GO:0090288,GO:0097159,GO:0097184,GO:0097305,GO:0098809,GO:1900744,GO:1900745,GO:1900746,GO:1900747,GO:1901265,GO:1901292,GO:1901342,GO:1901343,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901698,GO:1901700,GO:1902494,GO:1902531,GO:1902532,GO:1902533,GO:1902547,GO:1902548,GO:2000026,GO:2000116,GO:2000181,GO:2000377,GO:2000379,GO:2001056,GO:2001212,GO:2001213 1.17.1.4,1.17.3.2,1.2.3.1 4.206e-277 894.0
HKD2_k127_7769389_1 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 5.592e-220 698.0
HKD2_k127_7769389_2 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000005466 193.0
HKD2_k127_7769389_3 alpha beta - - - 0.00000000000000000000000000000001129 132.0
HKD2_k127_7769389_4 acetyltransferase K03828 - - 0.0000000000000003858 86.0
HKD2_k127_7772583_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 308.0
HKD2_k127_7772583_1 DTW K05812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000224 278.0
HKD2_k127_7772583_2 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000003372 157.0
HKD2_k127_7772583_3 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000002214 156.0
HKD2_k127_7772583_4 Aspartyl Asparaginyl beta-hydroxylase K12979 - - 0.000000000000000000000000001735 122.0
HKD2_k127_7773108_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000004825 228.0
HKD2_k127_7773108_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000008779 156.0
HKD2_k127_7773108_2 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000000000000000003225 112.0
HKD2_k127_7773108_3 regulator of chromosome condensation, RCC1 - - - 0.0002252 49.0
HKD2_k127_7775993_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000009558 230.0
HKD2_k127_7775993_1 - - - - 0.0000000000000000000000000000000000000000000000000001261 192.0
HKD2_k127_7775993_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000007 161.0
HKD2_k127_7775993_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000005676 145.0
HKD2_k127_7775993_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000018 128.0
HKD2_k127_7775993_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000006594 110.0
HKD2_k127_7775993_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000005643 98.0
HKD2_k127_7775993_8 - - - - 0.000000008278 65.0
HKD2_k127_7775993_9 VHL beta domain - - - 0.0001442 51.0
HKD2_k127_7776206_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 588.0
HKD2_k127_7776206_1 Lipopolysaccharide kinase (Kdo/WaaP) family K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000006276 214.0
HKD2_k127_7779017_0 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 1.393e-210 683.0
HKD2_k127_7779017_1 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009711 442.0
HKD2_k127_7779017_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000004743 221.0
HKD2_k127_7779017_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000001123 106.0
HKD2_k127_7779017_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000003859 97.0
HKD2_k127_7779017_5 Endonuclease/Exonuclease/phosphatase family - - - 0.00000005702 64.0
HKD2_k127_7780580_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 411.0
HKD2_k127_7780580_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000279 239.0
HKD2_k127_7780580_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000003417 199.0
HKD2_k127_7780580_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000001651 85.0
HKD2_k127_7780580_5 - - - - 0.0000001793 57.0
HKD2_k127_7791681_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.828e-232 730.0
HKD2_k127_7791681_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005447 275.0
HKD2_k127_7791681_2 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000001483 243.0
HKD2_k127_7791681_3 Cytochrome c - - - 0.000000000000004534 79.0
HKD2_k127_7791681_4 metalloendopeptidase activity K01283 - 3.4.15.1 0.00000000000008845 77.0
HKD2_k127_7791681_5 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000000002426 66.0
HKD2_k127_7791681_6 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000003725 57.0
HKD2_k127_7792092_0 DNA-binding response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 547.0
HKD2_k127_7792092_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 417.0
HKD2_k127_7792092_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 307.0
HKD2_k127_7792092_3 OmpA family K02557 - - 0.00000000000000000000000000000000000000000000000000008246 196.0
HKD2_k127_7792092_4 Cytochrome c K00406,K03889,K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.0000000000000000000000000002046 118.0
HKD2_k127_7792092_5 cheY-homologous receiver domain - - - 0.000000000000000000009749 98.0
HKD2_k127_7792092_6 Thioredoxin-like - - - 0.000000000000005126 85.0
HKD2_k127_7792092_7 diguanylate cyclase - - - 0.0000000299 60.0
HKD2_k127_7799540_0 synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000003023 219.0
HKD2_k127_7799540_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000179 198.0
HKD2_k127_7799540_2 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000005642 164.0
HKD2_k127_7799540_3 Flagellar basal body rod K02396,K03333 - 1.1.3.6 0.000000000000000000000000000001948 135.0
HKD2_k127_7805314_0 Glycogen debranching enzyme - - - 0.0 1296.0
HKD2_k127_7805314_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1208.0
HKD2_k127_7805314_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 486.0
HKD2_k127_7805314_3 ROK family K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 303.0
HKD2_k127_7805314_4 Splits dipeptides with a prolyl residue in the C- terminal position K01271 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 296.0
HKD2_k127_7805314_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000009693 215.0
HKD2_k127_7805314_6 Lipocalin-like domain K03098 - - 0.0000000000000000000000000006103 121.0
HKD2_k127_7805314_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000005243 66.0
HKD2_k127_7812226_0 Voltage gated chloride channel K03281 - - 1.229e-209 672.0
HKD2_k127_7812226_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 307.0
HKD2_k127_7812226_2 protein kinase activity K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005582 287.0
HKD2_k127_7812226_3 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000001873 165.0
HKD2_k127_7812226_4 Copper binding proteins, plastocyanin/azurin family K00368 - 1.7.2.1 0.00000000000000000000000000000000000001176 160.0
HKD2_k127_7812226_5 CRS1_YhbY K07574 - - 0.00000000000000000000000002867 114.0
HKD2_k127_78201_0 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 514.0
HKD2_k127_78201_1 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 449.0
HKD2_k127_78201_10 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000122 214.0
HKD2_k127_78201_11 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000001536 204.0
HKD2_k127_78201_12 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000365 182.0
HKD2_k127_78201_13 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000001679 154.0
HKD2_k127_78201_14 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000001062 151.0
HKD2_k127_78201_15 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000003406 154.0
HKD2_k127_78201_17 Pfam Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000005136 139.0
HKD2_k127_78201_18 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000003964 124.0
HKD2_k127_78201_19 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000001254 107.0
HKD2_k127_78201_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 449.0
HKD2_k127_78201_20 Copper binding proteins, plastocyanin/azurin family - GO:0008150,GO:0008152,GO:0055114 - 0.00000000000000000004384 100.0
HKD2_k127_78201_21 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000006228 100.0
HKD2_k127_78201_23 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000001511 97.0
HKD2_k127_78201_24 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000529 99.0
HKD2_k127_78201_25 amine dehydrogenase activity - - - 0.0000000000000003113 85.0
HKD2_k127_78201_26 Redoxin - - - 0.00000000000001434 87.0
HKD2_k127_78201_27 Cytochrome c K07245,K14166 - - 0.0000000000014 78.0
HKD2_k127_78201_28 - - - - 0.000000001068 70.0
HKD2_k127_78201_29 CHAP domain - - - 0.0000003691 61.0
HKD2_k127_78201_3 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 443.0
HKD2_k127_78201_30 Has antibacterial activity - GO:0000270,GO:0003674,GO:0003796,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0006897,GO:0006909,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0009605,GO:0009607,GO:0009617,GO:0016192,GO:0016787,GO:0016798,GO:0030203,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0042742,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0050830,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0061783,GO:0071704,GO:0097708,GO:0098542,GO:0098657,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000005113 61.0
HKD2_k127_78201_32 Protein of unknown function (DUF3341) - - - 0.000005224 55.0
HKD2_k127_78201_33 Transcriptional regulator - - - 0.000005315 56.0
HKD2_k127_78201_4 dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 418.0
HKD2_k127_78201_5 response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 404.0
HKD2_k127_78201_6 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 417.0
HKD2_k127_78201_7 Phosphate transport regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 390.0
HKD2_k127_78201_8 Cytochrome b(N-terminal)/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 358.0
HKD2_k127_78201_9 PFAM AMP-dependent synthetase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 309.0
HKD2_k127_7821206_0 Thioredoxin - - - 3.371e-196 631.0
HKD2_k127_7834050_0 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides - - - 0.00000000000000000000000000000000000000000000291 183.0
HKD2_k127_7834050_1 Homologues of snake disintegrins - - - 0.000004589 58.0
HKD2_k127_7836846_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 550.0
HKD2_k127_7836846_1 ERAP1-like C-terminal domain K01263 - 3.4.11.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 452.0
HKD2_k127_7836846_2 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 403.0
HKD2_k127_7836846_3 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 382.0
HKD2_k127_7836846_4 AAA domain (dynein-related subfamily) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 364.0
HKD2_k127_7836846_5 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000444 252.0
HKD2_k127_7836846_6 TM2 domain - - - 0.00000000000000005742 80.0
HKD2_k127_7837031_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 348.0
HKD2_k127_7837031_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 340.0
HKD2_k127_7843690_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 566.0
HKD2_k127_7843690_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 485.0
HKD2_k127_7843690_2 penicillin-binding protein K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 391.0
HKD2_k127_7843690_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 305.0
HKD2_k127_7843690_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000003862 215.0
HKD2_k127_7844157_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000001495 231.0
HKD2_k127_7844157_1 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000000000000005968 179.0
HKD2_k127_7844157_2 - - - - 0.00003245 54.0
HKD2_k127_7857685_0 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 502.0
HKD2_k127_7857685_1 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000119 185.0
HKD2_k127_7857685_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000004961 79.0
HKD2_k127_7862384_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001148 259.0
HKD2_k127_7879253_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 484.0
HKD2_k127_7879253_1 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 264.0
HKD2_k127_7879253_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001261 260.0
HKD2_k127_7879253_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000008634 241.0
HKD2_k127_7879253_4 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000000000000000000000000177 190.0
HKD2_k127_7879253_5 - - - - 0.00000000000000000000000000000000147 134.0
HKD2_k127_7879253_6 intracellular protease amidase - - - 0.00000000000000000000000000000003296 142.0
HKD2_k127_7879253_7 CAAX protease self-immunity - - - 0.0000000000000000000000000000003707 132.0
HKD2_k127_7880079_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 533.0
HKD2_k127_7895862_0 CobQ/CobB/MinD/ParA nucleotide binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009355 289.0
HKD2_k127_7895862_1 - - - - 0.000000000000000000000000000000000000000000000007419 181.0
HKD2_k127_7895862_2 TIR domain - - - 0.0000000000000000000000000000000001018 142.0
HKD2_k127_7895862_3 transporter component K07112 - - 0.00000000000000000000000006309 125.0
HKD2_k127_7895862_4 transporter component K07112 - - 0.000000000000000000000001462 114.0
HKD2_k127_7895862_5 - - - - 0.00000000000007544 82.0
HKD2_k127_7895862_6 tetratricopeptide repeat - - - 0.00000000001071 79.0
HKD2_k127_7895862_7 SIR2-like domain - - - 0.00001089 59.0
HKD2_k127_7895862_8 Carbohydrate family 9 binding domain-like - - - 0.00004595 57.0
HKD2_k127_7897621_0 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000000001015 201.0
HKD2_k127_7898745_0 penicillin-binding protein K03587 - 3.4.16.4 3.242e-248 790.0
HKD2_k127_7898745_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 352.0
HKD2_k127_7898745_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001437 299.0
HKD2_k127_7898745_4 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000005815 116.0
HKD2_k127_7901244_0 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 560.0
HKD2_k127_7902270_0 Putative glutamine amidotransferase - - - 3.774e-218 698.0
HKD2_k127_7902270_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 561.0
HKD2_k127_7902270_10 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000438 123.0
HKD2_k127_7902270_11 Armadillo/beta-catenin-like repeats - - - 0.0000000000000000000000000000773 136.0
HKD2_k127_7902270_13 Forkhead associated domain - - - 0.0000000000000000000001672 111.0
HKD2_k127_7902270_14 iron-sulfur cluster assembly K07126,K13819 - - 0.00000000000000000008651 94.0
HKD2_k127_7902270_15 Protein of unknown function (DUF721) - - - 0.000005036 56.0
HKD2_k127_7902270_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 535.0
HKD2_k127_7902270_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 396.0
HKD2_k127_7902270_4 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 289.0
HKD2_k127_7902270_5 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000000000000000000000000000008661 243.0
HKD2_k127_7902270_6 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000001699 226.0
HKD2_k127_7902270_8 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000005595 186.0
HKD2_k127_7928269_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 528.0
HKD2_k127_7928269_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001305 214.0
HKD2_k127_7928269_2 - - - - 0.000000000000000274 89.0
HKD2_k127_7928269_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000002638 81.0
HKD2_k127_7938541_0 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 297.0
HKD2_k127_7938541_1 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001355 278.0
HKD2_k127_7956484_0 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 366.0
HKD2_k127_7956484_1 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002045 283.0
HKD2_k127_7956484_2 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001386 243.0
HKD2_k127_7960189_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1364.0
HKD2_k127_7960189_1 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 362.0
HKD2_k127_7960189_2 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007591 273.0
HKD2_k127_7960189_3 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002951 250.0
HKD2_k127_7960189_4 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000009617 222.0
HKD2_k127_7960189_5 S-adenosylhomocysteine deaminase activity - - - 0.0000000000000000000000000000000000000000000000000004198 203.0
HKD2_k127_7960189_6 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000004129 112.0
HKD2_k127_7960189_7 Thioesterase-like superfamily - - - 0.0000000000003191 76.0
HKD2_k127_7960189_8 Transcription factor zinc-finger - - - 0.00000000001878 73.0
HKD2_k127_7960189_9 Putative heavy-metal-binding - - - 0.00000886 48.0
HKD2_k127_7964521_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1170.0
HKD2_k127_7964521_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 352.0
HKD2_k127_7974905_0 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 397.0
HKD2_k127_7974905_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 335.0
HKD2_k127_7974905_2 Belongs to the SUA5 family K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002778 269.0
HKD2_k127_7974905_3 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002617 271.0
HKD2_k127_7974905_4 PLD-like domain - - - 0.000000000000000000000000000000000000000000006442 177.0
HKD2_k127_7974905_5 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000001715 167.0
HKD2_k127_7974905_6 beta-fructofuranosidase activity - - - 0.000000000000000000000000000000000000000006039 174.0
HKD2_k127_7976611_0 response regulator K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 393.0
HKD2_k127_7976611_1 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 404.0
HKD2_k127_7976611_2 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 331.0
HKD2_k127_7976611_3 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000001985 194.0
HKD2_k127_7976611_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000004365 166.0
HKD2_k127_7976611_5 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000004782 147.0
HKD2_k127_7976611_6 Beta-L-arabinofuranosidase, GH127 - - - 0.0002904 53.0
HKD2_k127_7986420_0 Sigma-54 interaction domain K10941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 444.0
HKD2_k127_7986420_1 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 333.0
HKD2_k127_7986420_2 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007617 266.0
HKD2_k127_7986420_4 Domain of unknown function (DUF2520) K00969,K01488,K03574,K06211 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.1.22,2.7.7.1,2.7.7.18,3.5.4.4,3.6.1.55 0.000000000000000000000001674 116.0
HKD2_k127_7987383_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 476.0
HKD2_k127_7987383_1 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 444.0
HKD2_k127_7987383_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 334.0
HKD2_k127_7987383_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002697 258.0
HKD2_k127_7987383_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000001901 242.0
HKD2_k127_7987383_5 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000001778 206.0
HKD2_k127_7987383_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000003473 185.0
HKD2_k127_7996754_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 358.0
HKD2_k127_7996754_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000002127 233.0
HKD2_k127_7996754_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000002299 96.0
HKD2_k127_8012880_0 Tetratricopeptide repeat - - - 3.34e-236 754.0
HKD2_k127_8012880_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 525.0
HKD2_k127_8013987_0 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000008059 172.0
HKD2_k127_8018110_0 Domain of unknown function (DUF4132) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002775 293.0
HKD2_k127_8021368_0 Large family of predicted nucleotide-binding domains K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 462.0
HKD2_k127_8021368_1 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 308.0
HKD2_k127_8021368_2 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000103 264.0
HKD2_k127_8021368_3 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.0000000000000000000000000000000000003441 153.0
HKD2_k127_8021368_4 Preprotein translocase subunit YajC K03210 - - 0.000003051 55.0
HKD2_k127_8027349_0 Domain of unknown function (DUF1998) K06877 - - 6.269e-311 971.0
HKD2_k127_8027349_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.483e-252 790.0
HKD2_k127_8027349_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 459.0
HKD2_k127_8027349_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 393.0
HKD2_k127_8027349_4 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 349.0
HKD2_k127_8027349_5 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 329.0
HKD2_k127_8027349_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000001714 191.0
HKD2_k127_8027349_7 YXWGXW repeat (2 copies) - - - 0.00000000000000000000000000000004893 133.0
HKD2_k127_8027349_8 PFAM FecR protein K01179,K03933 - 3.2.1.4 0.0000000006297 73.0
HKD2_k127_8027707_0 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 300.0
HKD2_k127_8027707_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000004098 160.0
HKD2_k127_8027707_2 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000183 146.0
HKD2_k127_8027707_4 - - - - 0.00000000001313 74.0
HKD2_k127_8038995_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 464.0
HKD2_k127_8038995_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 306.0
HKD2_k127_8038995_10 Putative metal-binding motif - - - 0.000000000000000009532 95.0
HKD2_k127_8038995_2 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000286 278.0
HKD2_k127_8038995_3 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000006691 229.0
HKD2_k127_8038995_4 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000002515 250.0
HKD2_k127_8038995_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000003092 221.0
HKD2_k127_8038995_6 PFAM Formylglycine-generating sulfatase enzyme K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 0.000000000000000000000000000000000000000000008766 183.0
HKD2_k127_8038995_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000002517 166.0
HKD2_k127_8038995_8 Belongs to the peptidase S1B family - - - 0.000000000000000000000001008 118.0
HKD2_k127_8038995_9 Putative metal-binding motif - - - 0.000000000000000000002192 106.0
HKD2_k127_8060659_0 repeat protein - - - 2.268e-218 693.0
HKD2_k127_8061640_0 Phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 383.0
HKD2_k127_8061640_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 322.0
HKD2_k127_8061640_2 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 299.0
HKD2_k127_8061640_3 PA14 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003566 263.0
HKD2_k127_8061640_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000006057 183.0
HKD2_k127_8061640_5 - - - - 0.0000007102 58.0
HKD2_k127_8063377_0 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002032 262.0
HKD2_k127_8063377_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000009834 151.0
HKD2_k127_8063377_2 cell adhesion involved in biofilm formation - - - 0.000000000000000000008426 104.0
HKD2_k127_8063377_3 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000001454 100.0
HKD2_k127_8063377_4 Cytochrome c - - - 0.00006775 53.0
HKD2_k127_8068916_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 419.0
HKD2_k127_8068916_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001182 302.0
HKD2_k127_8068916_2 'Cold-shock' DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000001532 186.0
HKD2_k127_8068916_3 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.00000000000000000000000000000000000000000000002853 183.0
HKD2_k127_8068916_5 ATPase activity K01990 - - 0.000000000000000000001133 110.0
HKD2_k127_8080249_0 Protein of unknown function (DUF3089) - - - 0.000000000000000000000000000000000000000000000000001076 198.0
HKD2_k127_8080249_1 GON domain - - - 0.0000000000000000000000173 115.0
HKD2_k127_8080249_2 polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000009091 87.0
HKD2_k127_8083556_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 366.0
HKD2_k127_8083556_1 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009087 270.0
HKD2_k127_8083556_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001842 254.0
HKD2_k127_8083556_3 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000006541 217.0
HKD2_k127_8083556_4 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000001301 138.0
HKD2_k127_8083556_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000002115 139.0
HKD2_k127_8100682_0 Major Facilitator Superfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009177 582.0
HKD2_k127_8100682_1 Biotin-lipoyl like K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 293.0
HKD2_k127_8100682_2 regulatory protein TetR - - - 0.00000000000000000001187 103.0
HKD2_k127_8100682_3 outer membrane efflux protein K03287 - - 0.0000000001723 72.0
HKD2_k127_8106591_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000001376 248.0
HKD2_k127_8108426_0 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000001931 233.0
HKD2_k127_8108426_1 Heme NO binding - - - 0.0000000000000000000000000000000006617 137.0
HKD2_k127_8112651_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 6.025e-263 834.0
HKD2_k127_8112651_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 457.0
HKD2_k127_8112651_10 membrane - - - 0.00000000000000000000000000000002521 135.0
HKD2_k127_8112651_11 cell envelope organization K05807,K08309 - - 0.00000000000000000000000000001589 132.0
HKD2_k127_8112651_12 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000000000134 120.0
HKD2_k127_8112651_13 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000453 99.0
HKD2_k127_8112651_16 WD-40 repeat - - - 0.00000472 60.0
HKD2_k127_8112651_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 348.0
HKD2_k127_8112651_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 326.0
HKD2_k127_8112651_4 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 314.0
HKD2_k127_8112651_5 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 299.0
HKD2_k127_8112651_6 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001002 259.0
HKD2_k127_8112651_7 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000001033 216.0
HKD2_k127_8112651_8 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000001148 234.0
HKD2_k127_8112651_9 membrane - - - 0.0000000000000000000000000000000000002459 148.0
HKD2_k127_8116174_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 571.0
HKD2_k127_8116174_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 342.0
HKD2_k127_8116174_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000009622 177.0
HKD2_k127_8116174_11 protein trimerization - - - 0.00000000000000000000000000000000000000002361 169.0
HKD2_k127_8116174_12 SPFH domain / Band 7 family - - - 0.00000000000000000000000000000000000000005087 161.0
HKD2_k127_8116174_13 PFAM regulatory protein TetR - - - 0.00000000000000000000000001765 116.0
HKD2_k127_8116174_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 300.0
HKD2_k127_8116174_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 297.0
HKD2_k127_8116174_4 lipoprotein transporter activity K02003,K09814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000448 247.0
HKD2_k127_8116174_5 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007703 260.0
HKD2_k127_8116174_6 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003053 256.0
HKD2_k127_8116174_7 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000001022 227.0
HKD2_k127_8116174_8 DNA-binding regulatory protein K03088 - - 0.000000000000000000000000000000000000000000000000001275 197.0
HKD2_k127_8116174_9 Methyltransferase small domain K15460 - 2.1.1.223 0.000000000000000000000000000000000000000000000000004222 190.0
HKD2_k127_8129026_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 614.0
HKD2_k127_8129026_1 UvrD/REP helicase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 501.0
HKD2_k127_8129026_2 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000061 207.0
HKD2_k127_8129026_3 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000009278 120.0
HKD2_k127_8136764_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.427e-303 939.0
HKD2_k127_8136764_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000007041 233.0
HKD2_k127_8136764_2 repeat protein - - - 0.00000000000000000000000000000001342 134.0
HKD2_k127_8136764_3 Ribbon-helix-helix domain - - - 0.00000000000000000000008142 102.0
HKD2_k127_8160858_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 345.0
HKD2_k127_8160858_1 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006667 269.0
HKD2_k127_8160858_2 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000004296 176.0
HKD2_k127_8160858_3 protein conserved in bacteria K07192 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000006676 93.0
HKD2_k127_8160858_4 PFAM Ion K10716 - - 0.00001433 52.0
HKD2_k127_8161373_0 Protein kinase domain - - - 1.041e-218 726.0
HKD2_k127_8161373_1 ABC transporter, ATP-binding protein - - - 5.274e-215 680.0
HKD2_k127_8161373_11 WD40-like Beta Propeller Repeat - - - 0.00004273 55.0
HKD2_k127_8161373_12 protein kinase activity - - - 0.0000448 54.0
HKD2_k127_8161373_2 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 367.0
HKD2_k127_8161373_3 LytTr DNA-binding domain K02477,K07705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002146 254.0
HKD2_k127_8161373_4 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001167 237.0
HKD2_k127_8161373_5 Cytochrome c - - - 0.0000000000000000000000000000000000000000000015 175.0
HKD2_k127_8161373_6 - - - - 0.00000000000000000000000000000000015 141.0
HKD2_k127_8161373_7 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000006052 131.0
HKD2_k127_8161373_8 Putative zinc- or iron-chelating domain K06940 - - 0.000000001817 64.0
HKD2_k127_8161469_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 359.0
HKD2_k127_8161469_1 Belongs to the ompA family K03640 - - 0.000009878 53.0
HKD2_k127_8169627_0 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 522.0
HKD2_k127_8169627_1 Major Facilitator Superfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 419.0
HKD2_k127_8169627_2 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 384.0
HKD2_k127_8169627_3 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000009405 197.0
HKD2_k127_8186338_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 454.0
HKD2_k127_8186338_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007543 278.0
HKD2_k127_8186338_2 AAA domain - - - 0.00000000000000000000000000000000001035 149.0
HKD2_k127_8186338_3 Cupredoxin-like domain - - - 0.0000000726 64.0
HKD2_k127_8187971_0 PD-(D/E)XK nuclease superfamily - - - 0.0 1050.0
HKD2_k127_8187971_1 UvrD/REP helicase N-terminal domain - - - 2.726e-226 748.0
HKD2_k127_8187971_2 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 551.0
HKD2_k127_8250099_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 421.0
HKD2_k127_8250099_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 339.0
HKD2_k127_8250099_2 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000000002439 96.0
HKD2_k127_8250099_3 Haloacid dehalogenase-like hydrolase - - - 0.00000000000001258 78.0
HKD2_k127_8259654_0 Bacterial regulatory protein, Fis family K02584 - - 3.484e-289 934.0
HKD2_k127_8259654_1 Cytochrome b subunit of the bc complex K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 422.0
HKD2_k127_8259654_10 PBS lyase HEAT-like repeat - - - 0.00000003317 67.0
HKD2_k127_8259654_11 Domain of unknown function (DUF2383) - - - 0.0000002704 56.0
HKD2_k127_8259654_2 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 317.0
HKD2_k127_8259654_4 Putative esterase - - - 0.00000000000000000000000000000000000000000000001997 190.0
HKD2_k127_8259654_5 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.000000000000000000000000000000000000000000002232 170.0
HKD2_k127_8259654_6 Nitroreductase family - - - 0.000000000000000000000000000000000000000000007514 171.0
HKD2_k127_8259654_7 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000001533 164.0
HKD2_k127_8259654_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000001814 149.0
HKD2_k127_8299949_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.061e-211 671.0
HKD2_k127_8299949_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 607.0
HKD2_k127_8299949_2 Flagellar Motor Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 579.0
HKD2_k127_8299949_3 HAMP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 352.0
HKD2_k127_8299949_4 Aminotransferase class-III K09251 - 2.6.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004201 288.0
HKD2_k127_8299949_5 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002312 278.0
HKD2_k127_8299949_6 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000001506 181.0
HKD2_k127_8299949_7 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000001504 180.0
HKD2_k127_8299949_8 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000001978 149.0
HKD2_k127_831804_0 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane K18093 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003415 256.0
HKD2_k127_831804_1 Bacterial protein of unknown function (DUF882) - - - 0.0000000000002496 78.0
HKD2_k127_831804_2 Serine aminopeptidase, S33 - - - 0.000273 52.0
HKD2_k127_8324941_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 445.0
HKD2_k127_8338570_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 467.0
HKD2_k127_8338570_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000001094 222.0
HKD2_k127_8338570_2 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000001068 214.0
HKD2_k127_8338570_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000001405 201.0
HKD2_k127_8338570_4 Cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000002249 172.0
HKD2_k127_8348712_0 Family membership - - - 7.412e-233 767.0
HKD2_k127_8348712_1 heat shock protein binding - - - 1.033e-216 715.0
HKD2_k127_8348712_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000003019 216.0
HKD2_k127_8348712_11 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000002532 233.0
HKD2_k127_8348712_12 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000000000000001173 203.0
HKD2_k127_8348712_14 heat shock protein binding - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000001201 104.0
HKD2_k127_8348712_15 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000008162 90.0
HKD2_k127_8348712_16 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000001296 76.0
HKD2_k127_8348712_17 - - - - 0.000000000004849 70.0
HKD2_k127_8348712_18 T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000001153 73.0
HKD2_k127_8348712_19 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000002359 59.0
HKD2_k127_8348712_2 Sulfate permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 615.0
HKD2_k127_8348712_20 M6 family metalloprotease domain protein - - - 0.0000003246 61.0
HKD2_k127_8348712_21 Belongs to the glycosyl hydrolase 18 family - - - 0.000006152 58.0
HKD2_k127_8348712_3 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 471.0
HKD2_k127_8348712_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 441.0
HKD2_k127_8348712_6 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007683 282.0
HKD2_k127_8348712_7 NADP oxidoreductase coenzyme F420-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002596 265.0
HKD2_k127_8348712_8 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000004086 231.0
HKD2_k127_8348712_9 peptidase K19304 - - 0.0000000000000000000000000000000000000000000000000000000000000001721 231.0
HKD2_k127_8371052_0 Alpha-amylase domain K01176 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 597.0
HKD2_k127_8371052_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 554.0
HKD2_k127_8371052_2 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 377.0
HKD2_k127_8371052_3 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003826 266.0
HKD2_k127_8371052_4 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000285 262.0
HKD2_k127_8371052_5 protein kinase activity K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000004504 241.0
HKD2_k127_8371052_6 Rare lipoprotein A (RlpA)-like double-psi beta-barrel K20628 - - 0.000000000000001273 86.0
HKD2_k127_8374642_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 325.0
HKD2_k127_8374642_2 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000001125 268.0
HKD2_k127_8374642_4 PHB/PHA accumulation regulator DNA-binding domain - - - 0.000000000000000000000000000000000000000000000003986 179.0
HKD2_k127_8374642_5 Redoxin K02199 - - 0.0000000000000000000000000000000004636 138.0
HKD2_k127_8378195_0 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 529.0
HKD2_k127_8378195_1 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 319.0
HKD2_k127_8378195_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000003517 51.0
HKD2_k127_8381259_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 392.0
HKD2_k127_8435293_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003947 235.0
HKD2_k127_8435293_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000005726 213.0
HKD2_k127_8435293_3 - - - - 0.000000000000000000002057 99.0
HKD2_k127_8435345_0 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 391.0
HKD2_k127_8435345_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 389.0
HKD2_k127_8435345_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000007121 157.0
HKD2_k127_8435345_4 FCD - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043207,GO:0043565,GO:0044403,GO:0044419,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000857 94.0
HKD2_k127_8442971_0 Amidohydrolase family - - - 3.184e-220 692.0
HKD2_k127_8442971_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000004281 113.0
HKD2_k127_84524_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 384.0
HKD2_k127_84524_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 358.0
HKD2_k127_8460144_0 Major Facilitator Superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 435.0
HKD2_k127_8460144_1 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000003679 124.0
HKD2_k127_8460144_3 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000009323 74.0
HKD2_k127_8460144_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00007302 46.0
HKD2_k127_8460144_5 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0001171 52.0
HKD2_k127_8460144_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0008889 52.0
HKD2_k127_8471650_0 PA14 domain - - - 0.00000000000000000000000006885 113.0
HKD2_k127_8471650_1 - - - - 0.000000000000004681 85.0
HKD2_k127_8471650_2 BON domain - - - 0.00000000003676 75.0
HKD2_k127_84754_0 alpha beta - - - 0.0000000000000000000000000000000000001716 155.0
HKD2_k127_8490739_0 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000002997 178.0
HKD2_k127_8490739_1 NUDIX domain - - - 0.0000000000000000000107 102.0
HKD2_k127_852390_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 GO:0000272,GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0005981,GO:0006073,GO:0006091,GO:0006109,GO:0006112,GO:0006810,GO:0006887,GO:0006955,GO:0007275,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0008340,GO:0009056,GO:0009057,GO:0009251,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010259,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0012505,GO:0015980,GO:0016052,GO:0016192,GO:0016740,GO:0016757,GO:0016758,GO:0019222,GO:0019842,GO:0030141,GO:0030170,GO:0030246,GO:0030424,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032501,GO:0032502,GO:0032881,GO:0032940,GO:0032991,GO:0034774,GO:0035578,GO:0036094,GO:0036230,GO:0042119,GO:0042582,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043467,GO:0043470,GO:0043471,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044422,GO:0044424,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045819,GO:0045913,GO:0046903,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0048856,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0055114,GO:0060205,GO:0060255,GO:0062012,GO:0062013,GO:0065007,GO:0070013,GO:0070279,GO:0070873,GO:0070875,GO:0071704,GO:0080090,GO:0097159,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:1901363,GO:1901575 2.4.1.1 2.449e-261 839.0
HKD2_k127_852390_1 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 532.0
HKD2_k127_852390_2 Predicted methyltransferase regulatory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002873 241.0
HKD2_k127_852390_3 PFAM Thioredoxin K05838 - - 0.000000000003679 78.0
HKD2_k127_8547087_0 WD40-like Beta Propeller Repeat - - - 5e-324 1029.0
HKD2_k127_8547087_1 Protein conserved in bacteria K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 645.0
HKD2_k127_8547087_2 lycopene cyclase K06443 - 5.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 379.0
HKD2_k127_8547087_3 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 345.0
HKD2_k127_8547087_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 310.0
HKD2_k127_8547087_5 Belongs to the FPP GGPP synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009527 269.0
HKD2_k127_8547087_6 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.00000000000000000001026 100.0
HKD2_k127_8572562_0 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002596 274.0
HKD2_k127_8572562_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000002314 238.0
HKD2_k127_8572562_2 PEGA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000489 226.0
HKD2_k127_8572562_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000004174 210.0
HKD2_k127_8572562_4 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000004589 205.0
HKD2_k127_8572562_5 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000001165 135.0
HKD2_k127_8572562_7 - - - - 0.0000001351 63.0
HKD2_k127_8572562_8 serine threonine protein kinase - - - 0.000003314 60.0
HKD2_k127_8573831_1 40-residue YVTN family beta-propeller repeat - - - 0.00000001027 65.0
HKD2_k127_8580888_0 Class II Aldolase and Adducin N-terminal domain - - - 1.809e-208 668.0
HKD2_k127_8640916_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 571.0
HKD2_k127_8640916_1 succinate dehydrogenase K00241 - - 0.00000000000000000000001015 111.0
HKD2_k127_866707_0 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 351.0
HKD2_k127_866707_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000008424 235.0
HKD2_k127_866707_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000002085 208.0
HKD2_k127_866707_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000001202 117.0
HKD2_k127_866804_0 Aconitase family (aconitate hydratase) - - - 9.529e-287 893.0
HKD2_k127_866804_1 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 314.0
HKD2_k127_866804_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000009531 248.0
HKD2_k127_866804_3 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000002414 229.0
HKD2_k127_866804_4 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000002758 225.0
HKD2_k127_866804_5 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000003587 168.0
HKD2_k127_866804_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000002586 138.0
HKD2_k127_866804_7 Protein of unknown function (DUF1059) - - - 0.0000000000005512 72.0
HKD2_k127_8682379_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 310.0
HKD2_k127_8682379_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000005796 239.0
HKD2_k127_8682379_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000006748 76.0
HKD2_k127_8682763_0 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 307.0
HKD2_k127_8804519_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 424.0
HKD2_k127_8804519_1 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000002969 227.0
HKD2_k127_8804519_2 Thiopurine S-methyltransferase (TPMT) K00569 - 2.1.1.67 0.000000000000000000000000000000000000002435 158.0
HKD2_k127_8804519_3 Belongs to the peptidase S1B family - - - 0.00000000000000000008176 102.0
HKD2_k127_8804519_4 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000001153 81.0
HKD2_k127_8873546_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 507.0
HKD2_k127_8873546_1 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 515.0
HKD2_k127_8873546_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 338.0
HKD2_k127_8873546_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000003177 183.0
HKD2_k127_8873546_5 COG1073 hydrolases of the alpha beta superfamily - - - 0.000000000000003205 90.0
HKD2_k127_8873546_6 pyrroloquinoline quinone binding - - - 0.00001879 58.0
HKD2_k127_8879773_0 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000002399 251.0
HKD2_k127_8879773_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000001014 201.0
HKD2_k127_8879773_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000003954 164.0
HKD2_k127_8879773_6 Heavy-metal resistance - - - 0.0000000000000000000002372 104.0
HKD2_k127_8879773_7 Thiamine biosynthesis K03154 - - 0.00000000001487 64.0
HKD2_k127_8879773_8 Transcriptional regulatory protein, C terminal - - - 0.000001116 53.0
HKD2_k127_8886918_0 Domain of unknown function (DUF4132) - - - 0.000000000000000000000000000000000000000000000000000000000000007201 247.0
HKD2_k127_8886918_1 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.0000000007712 71.0
HKD2_k127_8932597_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004773 274.0
HKD2_k127_8932597_1 - - - - 0.000000000000000000000000000000000000001986 156.0
HKD2_k127_8944273_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 624.0
HKD2_k127_8944273_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000213 201.0
HKD2_k127_8944273_2 FHA domain - - - 0.000000000000000000001593 106.0
HKD2_k127_8944800_0 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 531.0
HKD2_k127_8944800_1 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000153 125.0
HKD2_k127_8944815_0 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 288.0
HKD2_k127_8944815_1 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008382 289.0
HKD2_k127_8944815_2 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000001034 149.0
HKD2_k127_8944815_3 serine threonine protein kinase - - - 0.00000000000000000000000000000007891 144.0
HKD2_k127_8945182_1 histone H2A K63-linked ubiquitination K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000007447 198.0
HKD2_k127_8945182_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000009978 77.0
HKD2_k127_8945182_3 DUF218 domain - - - 0.0000003691 63.0
HKD2_k127_8947032_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 9.475e-261 816.0
HKD2_k127_8947032_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001428 269.0
HKD2_k127_8947032_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 0.000000000003803 73.0
HKD2_k127_8949238_0 Flagellar Motor Protein K11892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 306.0
HKD2_k127_8949238_1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel K20628 - - 0.00000000000000000000000000000000000000000000000000000000000000000005068 241.0
HKD2_k127_8949238_2 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000004294 232.0
HKD2_k127_8950581_0 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 429.0
HKD2_k127_8950581_1 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 414.0
HKD2_k127_8950581_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 361.0
HKD2_k127_8950581_3 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 353.0
HKD2_k127_8950581_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000026 214.0
HKD2_k127_8950581_5 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000001382 197.0
HKD2_k127_8950581_6 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000001534 196.0
HKD2_k127_8950581_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000005522 158.0
HKD2_k127_8953623_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 364.0
HKD2_k127_8953623_1 Cytochrome c K00406,K03889,K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.00000000000000000000000000000000000007375 150.0
HKD2_k127_8953623_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K04040,K20616 - 2.5.1.133,2.5.1.62 0.00000001116 68.0
HKD2_k127_8953623_3 Transcriptional regulatory protein, C terminal K07663 - - 0.00000002362 63.0
HKD2_k127_8957297_0 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 382.0
HKD2_k127_8957297_1 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 367.0
HKD2_k127_8957297_2 cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007839 249.0
HKD2_k127_8957297_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000003473 100.0
HKD2_k127_8959619_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 307.0
HKD2_k127_8959619_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000002737 186.0
HKD2_k127_8959619_2 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000004573 159.0
HKD2_k127_8959619_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000009498 126.0
HKD2_k127_8963818_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 461.0
HKD2_k127_8963818_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000001146 157.0
HKD2_k127_8963818_2 KH domain K06960 - - 0.000000000000000000000153 100.0
HKD2_k127_8963818_4 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000004784 92.0
HKD2_k127_8964035_0 Radical SAM - - - 2.07e-210 667.0
HKD2_k127_8964035_1 RelA SpoT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 419.0
HKD2_k127_8964035_2 Lamin Tail Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001166 248.0
HKD2_k127_8964035_3 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000002291 243.0
HKD2_k127_8964035_4 deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000008899 142.0
HKD2_k127_8964035_5 SnoaL-like domain - - - 0.00000000000000000000000000005056 121.0
HKD2_k127_8970063_0 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000002111 233.0
HKD2_k127_8970063_1 transmembrane transporter activity - - - 0.0000000000000000000000000002296 115.0
HKD2_k127_8970063_2 - - - - 0.000000000000007717 84.0
HKD2_k127_8971681_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 520.0
HKD2_k127_8971681_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 475.0
HKD2_k127_8971681_10 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000008027 247.0
HKD2_k127_8971681_11 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000001102 194.0
HKD2_k127_8971681_12 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000000000000000000002473 201.0
HKD2_k127_8971681_13 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000005143 144.0
HKD2_k127_8971681_15 - - - - 0.00000000000000000000000004342 119.0
HKD2_k127_8971681_16 DNA-templated transcription, initiation K03088 - - 0.0000000000000000001341 99.0
HKD2_k127_8971681_17 - - - - 0.0000000003557 70.0
HKD2_k127_8971681_18 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain K05989 - 3.2.1.40 0.000002907 54.0
HKD2_k127_8971681_19 Bacterial regulatory proteins, tetR family - - - 0.00002742 54.0
HKD2_k127_8971681_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 406.0
HKD2_k127_8971681_20 Acetyltransferase (GNAT) domain - - - 0.0007271 52.0
HKD2_k127_8971681_3 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 370.0
HKD2_k127_8971681_4 Signal transduction histidine kinase, nitrogen specific - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 368.0
HKD2_k127_8971681_5 serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 364.0
HKD2_k127_8971681_6 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 346.0
HKD2_k127_8971681_7 IgGFc binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 322.0
HKD2_k127_8971681_8 ATP-grasp K17810 - 6.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 314.0
HKD2_k127_8972103_0 hydrolase activity, hydrolyzing O-glycosyl compounds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 475.0
HKD2_k127_8972103_1 - - - - 0.000000000000000000000000000000000000000000000002967 184.0
HKD2_k127_8975897_0 repeat protein - - - 3.842e-200 636.0
HKD2_k127_8978944_0 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K01126,K10716 - 3.1.4.46 1.013e-194 640.0
HKD2_k127_8978944_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 614.0
HKD2_k127_8978944_10 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000001018 222.0
HKD2_k127_8978944_11 Methyl-accepting Chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000001071 188.0
HKD2_k127_8978944_12 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000373 175.0
HKD2_k127_8978944_13 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000001976 173.0
HKD2_k127_8978944_14 dehydratase - - - 0.00000000000000000000000000000000000000004941 159.0
HKD2_k127_8978944_15 Spermidine synthase - - - 0.00000000000000000000000000000009451 143.0
HKD2_k127_8978944_16 - - - - 0.00000000000000000000000001274 115.0
HKD2_k127_8978944_17 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000001943 110.0
HKD2_k127_8978944_18 cellulose binding - - - 0.00000000000000003399 96.0
HKD2_k127_8978944_2 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 591.0
HKD2_k127_8978944_20 Domain of unknown function (DUF4920) - - - 0.00000000000002273 78.0
HKD2_k127_8978944_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 476.0
HKD2_k127_8978944_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 436.0
HKD2_k127_8978944_5 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 353.0
HKD2_k127_8978944_6 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 353.0
HKD2_k127_8978944_7 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 318.0
HKD2_k127_8978944_8 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001547 259.0
HKD2_k127_8978944_9 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001459 269.0
HKD2_k127_8980542_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 392.0
HKD2_k127_8980542_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001109 275.0
HKD2_k127_8980542_2 synthase K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009899 275.0
HKD2_k127_8980542_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001055 251.0
HKD2_k127_8980542_4 Belongs to the enoyl-CoA hydratase isomerase family K15313 - - 0.0000000000000000000000000000000000000000000000000000000895 211.0
HKD2_k127_8980542_5 enoyl-CoA hydratase K15312 - - 0.0000000000000000000000000000000000004755 149.0
HKD2_k127_8980542_6 Phosphopantetheine attachment site K02078 - - 0.000000000000000002161 97.0
HKD2_k127_8981216_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 400.0
HKD2_k127_8981216_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 316.0
HKD2_k127_8981216_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000002765 249.0
HKD2_k127_8981216_3 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.0000000000001084 72.0
HKD2_k127_8983416_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001665 266.0
HKD2_k127_8983416_1 Peptidase S46 - - - 0.000000000000000000000000000000000000000000000000000000000000002195 225.0
HKD2_k127_8983416_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000001216 195.0
HKD2_k127_8984796_0 fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 340.0
HKD2_k127_8984796_1 Domain of unknown function (DUF4132) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001386 280.0
HKD2_k127_8984796_10 Peptidase family S41 K03797 - 3.4.21.102 0.0001634 55.0
HKD2_k127_8984796_11 amine dehydrogenase activity - - - 0.0008031 52.0
HKD2_k127_8984796_2 Pectinacetylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008176 264.0
HKD2_k127_8984796_3 Proposed nucleic acid binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003513 248.0
HKD2_k127_8984796_4 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000006303 198.0
HKD2_k127_8984796_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000008598 166.0
HKD2_k127_8984796_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437 - 2.1.1.185,2.1.1.34 0.00000000000000000000000000000000000000000008943 178.0
HKD2_k127_8984796_7 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000002918 136.0
HKD2_k127_8984796_9 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000001119 62.0
HKD2_k127_8985083_0 OPT oligopeptide transporter protein - - - 5.176e-231 731.0
HKD2_k127_8985083_1 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 593.0
HKD2_k127_8985083_10 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000000000001034 175.0
HKD2_k127_8985083_11 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000002911 179.0
HKD2_k127_8985083_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000002915 176.0
HKD2_k127_8985083_13 LamB/YcsF family K07160 - - 0.0000000000000000000000000000000000009129 155.0
HKD2_k127_8985083_14 Sel1 repeat protein K07126 - - 0.0000000000000000000000000000000006209 152.0
HKD2_k127_8985083_15 Allophanate hydrolase subunit 2 - - - 0.00000000000000000000000000001155 135.0
HKD2_k127_8985083_16 cell envelope organization K05807,K08309 - - 0.00000000000000000000000001537 122.0
HKD2_k127_8985083_17 3-hydroxyacyl-CoA dehydrogenase domain protein K07516 - 1.1.1.35 0.00000000000007494 74.0
HKD2_k127_8985083_18 belongs to the sigma-70 factor family - - - 0.00000000001049 74.0
HKD2_k127_8985083_19 Glycosyl hydrolases family 43 - - - 0.000000006882 68.0
HKD2_k127_8985083_20 Protein of unknown function (DUF1566) - - - 0.00001048 57.0
HKD2_k127_8985083_21 - - - - 0.00004718 57.0
HKD2_k127_8985083_3 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009764 422.0
HKD2_k127_8985083_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 306.0
HKD2_k127_8985083_5 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 295.0
HKD2_k127_8985083_6 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004108 294.0
HKD2_k127_8985083_7 CoA-substrate-specific enzyme activase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005087 233.0
HKD2_k127_8985083_8 LamB/YcsF family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000004936 249.0
HKD2_k127_8985083_9 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000005392 198.0
HKD2_k127_8985734_0 Diguanylate cyclase - - - 7.125e-218 702.0
HKD2_k127_8985734_1 metallocarboxypeptidase activity K01206,K01218 - 3.2.1.51,3.2.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003607 294.0
HKD2_k127_8985734_2 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000004028 143.0
HKD2_k127_8985734_3 Stigma-specific protein, Stig1 - - - 0.000000000000000000000000003751 122.0
HKD2_k127_8985734_4 Stigma-specific protein, Stig1 - - - 0.000000000000000000001004 108.0
HKD2_k127_8985734_5 Stigma-specific protein, Stig1 - - - 0.000000209 63.0
HKD2_k127_8985734_6 peptide catabolic process K01256 - 3.4.11.2 0.00003539 56.0
HKD2_k127_898588_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 474.0
HKD2_k127_898588_1 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 488.0
HKD2_k127_898588_2 Redoxin - - - 0.00000000000000000000000000000000000000000000000242 181.0
HKD2_k127_898588_3 protein kinase activity - - - 0.00000000000000000000000000000000000000000002177 165.0
HKD2_k127_898588_4 Pkd domain containing protein - - - 0.000000000000001641 88.0
HKD2_k127_8986302_0 Prolyl oligopeptidase K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 456.0
HKD2_k127_8986302_1 Vitamin K epoxide reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 391.0
HKD2_k127_8986302_10 cell envelope organization K05807,K08309 - - 0.0000000002611 69.0
HKD2_k127_8986302_2 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 304.0
HKD2_k127_8986302_3 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001115 286.0
HKD2_k127_8986302_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000002019 261.0
HKD2_k127_8986302_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008081 267.0
HKD2_k127_8986302_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000005355 234.0
HKD2_k127_8986302_7 FHA domain - - - 0.000000000000000000000000000000000000000000006481 181.0
HKD2_k127_8986302_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000858 138.0
HKD2_k127_8986302_9 - - - - 0.00000000000000000001099 106.0
HKD2_k127_8986672_0 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 435.0
HKD2_k127_8986672_1 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 370.0
HKD2_k127_8986672_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000024 269.0
HKD2_k127_8986672_3 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003428 236.0
HKD2_k127_8994561_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 5.303e-307 967.0
HKD2_k127_8994561_1 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 343.0
HKD2_k127_8994561_2 conserved protein (DUF2183) - - - 0.00000000000000000000000000000000000000000000000000000001055 201.0
HKD2_k127_8994561_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000000000000007461 209.0
HKD2_k127_8994561_4 conserved protein (DUF2183) - - - 0.00000000000000000000000000000000000000000001603 168.0
HKD2_k127_8997101_0 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 548.0
HKD2_k127_8997101_1 - - - - 0.000000001165 71.0
HKD2_k127_8997101_2 PilZ domain - - - 0.000008028 59.0
HKD2_k127_8997101_3 - - - - 0.0001116 51.0
HKD2_k127_8999491_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K11206,K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000353 206.0
HKD2_k127_8999491_1 M6 family metalloprotease domain protein - - - 0.00000000444 69.0
HKD2_k127_9000022_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1385.0
HKD2_k127_9000022_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 451.0
HKD2_k127_9000022_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 296.0
HKD2_k127_9000022_3 Glycoside-hydrolase family GH114 - - - 0.00000000000000000000000000000000000000000000000000000000000009375 228.0
HKD2_k127_9000022_4 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000001056 198.0
HKD2_k127_9000022_5 - - - - 0.0000000000000000000000000000000001489 143.0
HKD2_k127_9003007_0 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 289.0
HKD2_k127_9003007_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000313 258.0
HKD2_k127_9003007_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000004214 213.0
HKD2_k127_9003007_3 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000002144 118.0
HKD2_k127_9007650_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001289 292.0
HKD2_k127_9007650_1 N-4 methylation of cytosine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009695 249.0
HKD2_k127_9007650_3 Domain of unknown function (DUF4142) K08995 - - 0.00000000000000000000006992 103.0
HKD2_k127_9007650_4 cytochrome P450 - - - 0.000000000001583 68.0
HKD2_k127_9012115_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 542.0
HKD2_k127_9012115_1 - - - - 0.00000001951 65.0
HKD2_k127_9012115_3 - - - - 0.0003484 53.0
HKD2_k127_9014159_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 291.0
HKD2_k127_9014159_1 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001253 269.0
HKD2_k127_9014159_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009314 261.0
HKD2_k127_9014159_3 MlaD protein K02067 - - 0.0000000004688 68.0
HKD2_k127_9022830_0 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 321.0
HKD2_k127_9022830_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000006269 216.0
HKD2_k127_9022830_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000003124 155.0
HKD2_k127_9022830_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000003271 127.0
HKD2_k127_9025125_0 B12 binding domain - - - 2.413e-199 629.0
HKD2_k127_9025125_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001912 235.0
HKD2_k127_9027318_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000003948 247.0
HKD2_k127_9027318_1 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.00000000000007268 72.0
HKD2_k127_9027548_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 447.0
HKD2_k127_9027548_1 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 289.0
HKD2_k127_9035601_0 VWA domain containing CoxE-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 456.0
HKD2_k127_9035601_1 Zinc finger, swim domain protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000009163 241.0
HKD2_k127_9035601_2 protein containing a von Willebrand factor type A (vWA) domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000019 184.0
HKD2_k127_9037522_0 Protein of unknown function (DUF455) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 307.0
HKD2_k127_9037522_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003095 240.0
HKD2_k127_9037522_2 Cysteine-rich CPCC - - - 0.0000000000000000000000000000005571 124.0
HKD2_k127_9037522_3 Heat shock 70 kDa protein K04043 - - 0.000000006679 63.0
HKD2_k127_9044290_0 - - - - 0.000000000000000000000000000000000000000000004439 182.0
HKD2_k127_9044290_1 Glycosyl hydrolases family 15 - - - 0.000000000000000000000000000000000000000000007853 179.0
HKD2_k127_9044290_2 GAF domain-containing protein K08968 - 1.8.4.14 0.0000000000000000000004243 101.0
HKD2_k127_9047863_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000002863 220.0
HKD2_k127_9047863_1 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000003339 207.0
HKD2_k127_9047863_2 TPR repeat - - - 0.00001057 58.0
HKD2_k127_9047863_3 carbohydrate binding K17513 - - 0.00004774 55.0
HKD2_k127_9048198_0 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004135 254.0
HKD2_k127_9048198_1 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000005254 240.0
HKD2_k127_9048198_2 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000009206 205.0
HKD2_k127_9048198_3 Putative modulator of DNA gyrase - - - 0.000000000000002461 76.0
HKD2_k127_9052381_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 3.754e-217 692.0
HKD2_k127_9052381_1 Histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 406.0
HKD2_k127_9052381_4 - - - - 0.000000000000000000000000009989 113.0
HKD2_k127_9053653_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001471 278.0
HKD2_k127_9053653_1 helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002466 237.0
HKD2_k127_9055225_0 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.000000000000000001932 85.0
HKD2_k127_9055225_1 cellular response to heat K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000001988 81.0
HKD2_k127_9066812_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 582.0
HKD2_k127_9066812_1 Uncharacterised protein family (UPF0158) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009427 317.0
HKD2_k127_9066812_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001527 303.0
HKD2_k127_9066812_3 nitric oxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001083 261.0
HKD2_k127_9066812_4 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000002922 218.0
HKD2_k127_9066812_5 alpha beta - - - 0.0000000000000000000000000000000000000187 155.0
HKD2_k127_9066812_7 histone H2A K63-linked ubiquitination - - - 0.00000000000000000003422 103.0
HKD2_k127_9066826_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 1.881e-308 962.0
HKD2_k127_9066826_1 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 550.0
HKD2_k127_9066826_10 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.0000000000000000000000000000000000000000000000000000009285 212.0
HKD2_k127_9066826_11 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000002044 112.0
HKD2_k127_9066826_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 380.0
HKD2_k127_9066826_3 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 329.0
HKD2_k127_9066826_4 Urease, gamma subunit K01430,K14048 - 3.5.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 312.0
HKD2_k127_9066826_5 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 299.0
HKD2_k127_9066826_6 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 296.0
HKD2_k127_9066826_7 GH3 auxin-responsive promoter - - - 0.00000000000000000000000000000000000000000000000000000000000000000002286 252.0
HKD2_k127_9066826_8 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000000000000000000000000000000007089 252.0
HKD2_k127_9066826_9 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000212 231.0
HKD2_k127_9071824_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 352.0
HKD2_k127_9071824_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000586 224.0
HKD2_k127_9071824_2 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000004396 218.0
HKD2_k127_9071824_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000009864 195.0
HKD2_k127_9071824_5 alpha/beta hydrolase fold K01055 - 3.1.1.24 0.0000000000000000000000000000000001799 151.0
HKD2_k127_9071824_7 peptidyl-prolyl cis-trans isomerase activity K01802,K03769,K03770 - 5.2.1.8 0.00000000000000008255 80.0
HKD2_k127_9075898_0 - - - - 4.421e-196 646.0
HKD2_k127_9075898_3 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000000000000000009478 86.0
HKD2_k127_9075898_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000003169 69.0
HKD2_k127_9077723_0 Domain of unknown function (DUF4175) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 623.0
HKD2_k127_9077723_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 319.0
HKD2_k127_9077723_2 SMART serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000005973 187.0
HKD2_k127_9093085_0 Domain of unknown function (DUF4132) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 413.0
HKD2_k127_9093085_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000001584 222.0
HKD2_k127_9102127_0 Pfam:DUF955 K07110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 501.0
HKD2_k127_9102127_1 Belongs to the malate synthase family K01638 - 2.3.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008044 280.0
HKD2_k127_9109964_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 573.0
HKD2_k127_9109964_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 310.0
HKD2_k127_9109964_10 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000005799 121.0
HKD2_k127_9109964_12 - - - - 0.000000000433 72.0
HKD2_k127_9109964_2 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004808 287.0
HKD2_k127_9109964_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005101 259.0
HKD2_k127_9109964_4 PilZ domain - - - 0.000000000000000000000000000000000000000000000000000000000006712 228.0
HKD2_k127_9109964_5 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000001172 181.0
HKD2_k127_9109964_6 glycoside hydrolase, family K07273 - - 0.000000000000000000000000000000000000000000119 176.0
HKD2_k127_9109964_7 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000001176 157.0
HKD2_k127_9109964_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000001709 147.0
HKD2_k127_9111786_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 362.0
HKD2_k127_9111786_1 chlorophyll binding K16191,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000325 235.0
HKD2_k127_9111786_2 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000007242 201.0
HKD2_k127_9111786_3 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000003619 159.0
HKD2_k127_9111786_4 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000000000273 124.0
HKD2_k127_9111786_5 - - - - 0.00000000000000000008609 94.0
HKD2_k127_9111786_6 Belongs to the HesB IscA family K13628 - - 0.00000000000000000009463 88.0
HKD2_k127_9111786_7 - - - - 0.000000000000003716 78.0
HKD2_k127_9118283_0 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 289.0
HKD2_k127_9118283_1 methyltransferase - - - 0.0000000000000000000000000000000001276 140.0
HKD2_k127_9118283_2 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0000009634 57.0
HKD2_k127_9118283_3 rRNA processing K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000001113 59.0
HKD2_k127_9119957_0 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 370.0
HKD2_k127_9119957_1 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005587 277.0
HKD2_k127_9119957_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.00000000000000000000000000000000000000000000000001804 192.0
HKD2_k127_9119957_3 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000004996 175.0
HKD2_k127_9119957_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03214 - - 0.00000000000000000000000001607 121.0
HKD2_k127_9119957_5 Carbohydrate family 9 binding domain-like - - - 0.000000000757 68.0
HKD2_k127_9120844_0 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 526.0
HKD2_k127_9120844_1 Two component regulator propeller - - - 0.0000000000000000004063 91.0
HKD2_k127_9121429_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 8.54e-312 973.0
HKD2_k127_9121429_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000004048 235.0
HKD2_k127_9121429_10 - - - - 0.000000001043 67.0
HKD2_k127_9121429_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K04760 - - 0.000000000000000000000000000000000000000000000000000000002669 207.0
HKD2_k127_9121429_3 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000000000000000000000000000001839 193.0
HKD2_k127_9121429_4 Methyltransferase domain K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000001079 179.0
HKD2_k127_9121429_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000001703 177.0
HKD2_k127_9121429_6 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000003161 172.0
HKD2_k127_9121429_8 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000001646 126.0
HKD2_k127_9121558_0 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 5.033e-259 837.0
HKD2_k127_9121558_1 Domain of unknown function (DUF4291) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002808 255.0
HKD2_k127_9121558_2 Domain of unknown function (DUF3463) - - - 0.00000000000000000000000000000000000000000000000000000000000001747 217.0
HKD2_k127_9121558_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000002291 154.0
HKD2_k127_9121558_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000503 135.0
HKD2_k127_9121558_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000001715 128.0
HKD2_k127_9127532_0 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 573.0
HKD2_k127_9127532_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001282 290.0
HKD2_k127_9127532_2 - - - - 0.00000000000000000000000000000000000006588 165.0
HKD2_k127_9127532_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000008676 102.0
HKD2_k127_9137183_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 430.0
HKD2_k127_9137183_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000547 396.0
HKD2_k127_9137183_2 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 315.0
HKD2_k127_9137183_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000002176 59.0
HKD2_k127_9143511_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 316.0
HKD2_k127_9143511_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 327.0
HKD2_k127_9143511_2 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004064 271.0
HKD2_k127_9143511_3 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000000000000000000000000000000000000000009916 167.0
HKD2_k127_9143511_5 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000008448 66.0
HKD2_k127_9143511_6 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000005008 70.0
HKD2_k127_9143511_7 Binds the 23S rRNA K02909 - - 0.0000001062 55.0
HKD2_k127_9147701_0 Transporter associated domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008292 266.0
HKD2_k127_9147701_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001247 256.0
HKD2_k127_9155817_0 CAAX amino terminal protease family - - - 0.0000000000000000000000000000000000000622 161.0
HKD2_k127_9155817_1 Family membership - - - 0.0000000000000004687 80.0
HKD2_k127_9156888_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 414.0
HKD2_k127_9156888_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 366.0
HKD2_k127_9156888_2 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000001992 252.0
HKD2_k127_9156888_3 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000005556 223.0
HKD2_k127_9156888_4 Cytochrome c - - - 0.00000000000000000000000000000003988 139.0
HKD2_k127_9156888_5 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000001109 113.0
HKD2_k127_9156888_6 Class III cytochrome C family - - - 0.000000000000868 80.0
HKD2_k127_9159148_0 PFAM AMP-dependent synthetase and ligase K04110 - 6.2.1.25 2.118e-221 698.0
HKD2_k127_9159148_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 2.944e-194 635.0
HKD2_k127_9159148_2 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 480.0
HKD2_k127_9159148_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000002186 281.0
HKD2_k127_9159148_4 HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001407 250.0
HKD2_k127_9159148_5 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000005991 92.0
HKD2_k127_9159148_6 PFAM Protein kinase K12132 - 2.7.11.1 0.000000000005188 79.0
HKD2_k127_9159148_7 - - - - 0.0000001998 56.0
HKD2_k127_916416_0 metallopeptidase activity K01081,K01183,K20276 - 3.1.3.5,3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 423.0
HKD2_k127_9166124_0 - - - - 0.0000000000000000000000000406 109.0
HKD2_k127_9166124_1 Transcription factor zinc-finger - - - 0.000000000000000000004853 98.0
HKD2_k127_9166124_2 N-formylglutamate amidohydrolase - - - 0.000000000000007177 83.0
HKD2_k127_9166124_3 - - - - 0.000000001364 70.0
HKD2_k127_9166363_0 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 301.0
HKD2_k127_9166363_2 - - - - 0.00000000000000000000000000000000000000000000000000002655 201.0
HKD2_k127_9174948_0 protein kinase activity - - - 0.0 1112.0
HKD2_k127_9174948_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 428.0
HKD2_k127_9174948_10 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000007496 126.0
HKD2_k127_9174948_13 PHP domain protein - - - 0.000000000000004159 90.0
HKD2_k127_9174948_14 domain, Protein - - - 0.000000000000445 80.0
HKD2_k127_9174948_16 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.000001258 61.0
HKD2_k127_9174948_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 340.0
HKD2_k127_9174948_4 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 341.0
HKD2_k127_9174948_6 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000181 273.0
HKD2_k127_9174948_7 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000004641 260.0
HKD2_k127_9174948_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009836 260.0
HKD2_k127_9174948_9 domain, Protein - - - 0.000000000000000000000000000000005772 140.0
HKD2_k127_9185502_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 423.0
HKD2_k127_9185502_1 glycoside hydrolase, family K07273 - - 0.000000000000000000000000000000000000003802 154.0
HKD2_k127_9186680_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 395.0
HKD2_k127_9186680_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 318.0
HKD2_k127_9186680_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000003243 209.0
HKD2_k127_9188976_0 HD domain - - - 7.899e-238 755.0
HKD2_k127_9188976_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 409.0
HKD2_k127_9188976_2 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 362.0
HKD2_k127_9188976_3 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 329.0
HKD2_k127_9188976_4 - - - - 0.00000000000000000000000000000000000000000000001298 191.0
HKD2_k127_9188976_5 YXWGXW repeat (2 copies) - - - 0.000000001957 68.0
HKD2_k127_9188976_6 VWA domain containing CoxE-like protein K09989 - - 0.000000005881 69.0
HKD2_k127_9214932_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.579e-207 676.0
HKD2_k127_9214932_1 Glycosyl transferase family 21 - - - 5.927e-205 646.0
HKD2_k127_9214932_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 318.0
HKD2_k127_9214932_3 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 301.0
HKD2_k127_9214932_4 ATP hydrolysis coupled proton transport - - - 0.0000000000000000000000000000000000000000002569 183.0
HKD2_k127_9214932_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000001856 169.0
HKD2_k127_9214932_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000002923 147.0
HKD2_k127_9214932_7 - - - - 0.000000000000000000000001008 118.0
HKD2_k127_9214932_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000004631 63.0
HKD2_k127_9214932_9 Ankyrin repeat K06867 - - 0.000001456 62.0
HKD2_k127_9219417_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002476 273.0
HKD2_k127_9219417_2 PLC-like phosphodiesterase - - - 0.0000000000000000000000000000000004479 144.0
HKD2_k127_9219417_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000422 147.0
HKD2_k127_9219417_4 Belongs to the ompA family - - - 0.000000000000000003007 98.0
HKD2_k127_9219417_5 Thrombospondin type 3 repeat - - - 0.00003866 57.0
HKD2_k127_9227268_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 571.0
HKD2_k127_9227268_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000002642 141.0
HKD2_k127_9227268_2 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.00000000000000000006252 91.0
HKD2_k127_9229892_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 506.0
HKD2_k127_9231676_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 512.0
HKD2_k127_9234191_0 Aminotransferase - - - 3.451e-207 649.0
HKD2_k127_9234191_1 DNA-binding response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 533.0
HKD2_k127_9234191_2 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004036 278.0
HKD2_k127_9234191_3 Rubrerythrin K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000004591 223.0
HKD2_k127_9234191_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000004788 199.0
HKD2_k127_9234191_5 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000000000000000000000001115 172.0
HKD2_k127_9234191_6 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000002458 139.0
HKD2_k127_9234191_7 Histidine kinase - - - 0.00000000000000000008313 101.0
HKD2_k127_9234191_8 Protein of unknown function (DUF1328) - - - 0.000000000001299 70.0
HKD2_k127_9234191_9 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.0000007445 57.0
HKD2_k127_9240365_0 Fad dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007345 290.0
HKD2_k127_9240365_1 diguanylate cyclase - - - 0.0000000000000000000002547 106.0
HKD2_k127_9240365_2 Transcription factor zinc-finger - - - 0.0000000721 65.0
HKD2_k127_9245280_0 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 3.381e-228 724.0
HKD2_k127_9245280_1 FAD dependent oxidoreductase K09879 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 521.0
HKD2_k127_9245280_2 lycopene cyclase K06443 - 5.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 369.0
HKD2_k127_9245280_3 Belongs to the FPP GGPP synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001559 265.0
HKD2_k127_9245280_4 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000002735 229.0
HKD2_k127_9245280_5 pyrroloquinoline quinone binding - - - 0.0004736 52.0
HKD2_k127_9255442_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 2.54e-231 751.0
HKD2_k127_9255442_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 452.0
HKD2_k127_9255442_10 Pfam:RRM_6 - - - 0.000000000000000000000000000000000007869 141.0
HKD2_k127_9255442_11 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000002085 124.0
HKD2_k127_9255442_12 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000805 129.0
HKD2_k127_9255442_13 - - - - 0.0000000000000000000000000002063 117.0
HKD2_k127_9255442_14 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000000006838 117.0
HKD2_k127_9255442_15 NUDIX hydrolase - - - 0.000000000000000000000000001014 121.0
HKD2_k127_9255442_18 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000007957 85.0
HKD2_k127_9255442_19 - - - - 0.00000000000000003564 89.0
HKD2_k127_9255442_2 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 443.0
HKD2_k127_9255442_21 WD40-like Beta Propeller Repeat - - - 0.00000000003369 75.0
HKD2_k127_9255442_23 Belongs to the ompA family - - - 0.00000006322 66.0
HKD2_k127_9255442_24 Ferredoxin - - - 0.0000007405 59.0
HKD2_k127_9255442_25 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000001799 61.0
HKD2_k127_9255442_3 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 351.0
HKD2_k127_9255442_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 297.0
HKD2_k127_9255442_5 transcription factor binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009406 273.0
HKD2_k127_9255442_6 Belongs to the ompA family K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000006885 251.0
HKD2_k127_9255442_7 deoxyhypusine monooxygenase activity K01932 - - 0.000000000000000000000000000000000000000000000000005509 209.0
HKD2_k127_9255442_8 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000001453 164.0
HKD2_k127_9255442_9 Sh3 type 3 domain protein K01185,K07184,K07260 - 3.2.1.17,3.4.17.14 0.00000000000000000000000000000000000001062 157.0
HKD2_k127_9258490_0 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 509.0
HKD2_k127_9258490_1 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.000000000000000000000000000000000000008507 163.0
HKD2_k127_9258490_2 YXWGXW repeat (2 copies) - - - 0.0000000000000741 78.0
HKD2_k127_9258490_3 Aminotransferase class-V - - - 0.00000002173 59.0
HKD2_k127_9263708_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 4.773e-256 802.0
HKD2_k127_9263708_1 Dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 532.0
HKD2_k127_9263708_10 R3H domain K06346 - - 0.000000000000000000000000000000000000000000003057 169.0
HKD2_k127_9263708_11 Peptidase M15 K02395 - - 0.0000000000000000000000000000000000000000004343 171.0
HKD2_k127_9263708_12 - - - - 0.0000000000000000000000000000000000000007906 154.0
HKD2_k127_9263708_13 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000005271 151.0
HKD2_k127_9263708_14 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000001229 147.0
HKD2_k127_9263708_15 - - - - 0.0000000000000000000000000000003538 132.0
HKD2_k127_9263708_2 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 462.0
HKD2_k127_9263708_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 441.0
HKD2_k127_9263708_4 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 331.0
HKD2_k127_9263708_5 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 322.0
HKD2_k127_9263708_6 Acyl-protein synthetase, LuxE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007521 289.0
HKD2_k127_9263708_7 Belongs to the peptidase S1B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000009219 244.0
HKD2_k127_9263708_9 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000006257 178.0
HKD2_k127_9272782_0 Periplasmic protein TonB links inner and outer membranes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 430.0
HKD2_k127_9272782_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000009503 250.0
HKD2_k127_9292810_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 373.0
HKD2_k127_9292810_1 Type II IV secretion system protein K02283,K03609 - - 0.000000000000000000000000000000000000000000000000001781 185.0
HKD2_k127_9292810_2 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000007685 153.0
HKD2_k127_9293765_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 558.0
HKD2_k127_929626_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 6.576e-195 653.0
HKD2_k127_929626_1 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 452.0
HKD2_k127_929626_10 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000641 286.0
HKD2_k127_929626_12 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000000000000000000007249 208.0
HKD2_k127_929626_13 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000004283 155.0
HKD2_k127_929626_14 pilus assembly protein PilW K02672 - - 0.000000000000000000000000000137 133.0
HKD2_k127_929626_16 type IV pilus modification protein PilV K02671,K02681 - - 0.00000000000001753 87.0
HKD2_k127_929626_18 Bacterial regulatory proteins, tetR family - - - 0.000000001446 66.0
HKD2_k127_929626_2 transmembrane transport K03442,K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 385.0
HKD2_k127_929626_20 protein transport across the cell outer membrane K02246,K08084 - - 0.00003483 55.0
HKD2_k127_929626_21 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0001327 53.0
HKD2_k127_929626_3 S1 domain K00243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 359.0
HKD2_k127_929626_4 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 333.0
HKD2_k127_929626_5 polysaccharide biosynthetic process K06409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 347.0
HKD2_k127_929626_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 297.0
HKD2_k127_929626_7 RNA-DNA hybrid ribonuclease activity K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 294.0
HKD2_k127_929626_8 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002796 299.0
HKD2_k127_929626_9 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008083 286.0
HKD2_k127_9296526_0 Carboxyl transferase domain - - - 2.961e-262 814.0
HKD2_k127_9296526_1 Flagellar basal body rod K02396 - - 0.0000000000000000000000000000000000000000000000000000000000004676 230.0
HKD2_k127_9296526_2 M6 family metalloprotease domain protein - - - 0.0000000004976 68.0
HKD2_k127_9299180_0 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 525.0
HKD2_k127_9299180_1 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 311.0
HKD2_k127_9299180_2 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000007562 199.0
HKD2_k127_9299180_3 Patatin-like phospholipase - - - 0.00000000003508 77.0
HKD2_k127_9318161_0 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 3.231e-235 736.0
HKD2_k127_9318161_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 454.0
HKD2_k127_9318161_10 Bacterial protein of unknown function (YtfJ_HI0045) K07109 - - 0.000000000000000000000000000000000000009995 162.0
HKD2_k127_9318161_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 419.0
HKD2_k127_9318161_3 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 328.0
HKD2_k127_9318161_4 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 324.0
HKD2_k127_9318161_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000005532 241.0
HKD2_k127_9318161_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000395 231.0
HKD2_k127_9318161_7 helix_turn_helix, mercury resistance K22491 - - 0.00000000000000000000000000000000000000000000000000000000000008806 224.0
HKD2_k127_9318161_8 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000001755 205.0
HKD2_k127_9318161_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000001495 207.0
HKD2_k127_9318636_0 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 514.0
HKD2_k127_9318636_1 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 486.0
HKD2_k127_9318636_2 phosphatase homologous to the C-terminal domain of histone macroH2A1 - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 397.0
HKD2_k127_9318636_3 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001755 235.0
HKD2_k127_9318730_0 Belongs to the ClpA ClpB family K03694 - - 2.157e-318 992.0
HKD2_k127_9318730_1 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 520.0
HKD2_k127_9318730_2 protein kinase activity K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 346.0
HKD2_k127_9318730_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 317.0
HKD2_k127_9318730_4 - - - - 0.00000000000000000000000000000000000000000000000293 181.0
HKD2_k127_9318730_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000001924 139.0
HKD2_k127_9318730_6 Multidrug transporter MatE K03327 - - 0.0000000000000001234 87.0
HKD2_k127_9318730_8 response regulator K02481,K07713 - - 0.0000003124 58.0
HKD2_k127_9323690_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 334.0
HKD2_k127_9323690_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001287 275.0
HKD2_k127_9323690_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000004073 257.0
HKD2_k127_9323690_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000613 139.0
HKD2_k127_9331022_0 AcrB/AcrD/AcrF family K15726 - - 4.982e-295 938.0
HKD2_k127_9331022_1 Heat shock 70 kDa protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 573.0
HKD2_k127_9331022_10 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000002189 130.0
HKD2_k127_9331022_2 Biotin carboxylase K01961,K01968 - 6.3.4.14,6.4.1.2,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 561.0
HKD2_k127_9331022_3 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 464.0
HKD2_k127_9331022_4 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 459.0
HKD2_k127_9331022_5 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 360.0
HKD2_k127_9331022_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000001836 288.0
HKD2_k127_9331022_7 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000001388 216.0
HKD2_k127_9331022_8 Flagellar basal body rod K02396,K03333 - 1.1.3.6 0.00000000000000000000000000000000000000000000000000006619 202.0
HKD2_k127_9331022_9 HlyD family secretion protein K15727 - - 0.0000000000000000000000000000000000000002029 167.0
HKD2_k127_9332575_0 Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA K00219,K09461 - 1.14.13.40,1.3.1.34 1.309e-254 807.0
HKD2_k127_9332575_1 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 473.0
HKD2_k127_9332575_2 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006735 256.0
HKD2_k127_9332575_3 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000104 257.0
HKD2_k127_9332575_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000004507 226.0
HKD2_k127_9332575_5 Histidine kinase K03406,K21470 - - 0.00000000000000000000000000000000000000000000000000004711 199.0
HKD2_k127_9332575_6 - - - - 0.0000000000000000000000000000000000000000000006137 176.0
HKD2_k127_9349189_0 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 349.0
HKD2_k127_9349189_1 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002403 241.0
HKD2_k127_9349189_2 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000000000006196 174.0
HKD2_k127_93535_0 Belongs to the glycosyl hydrolase 35 family K12308 - 3.2.1.23 1.446e-226 720.0
HKD2_k127_93535_1 Protein-arginine deiminase (PAD) middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 495.0
HKD2_k127_93535_2 Choline/ethanolamine kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 330.0
HKD2_k127_93535_3 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000009002 253.0
HKD2_k127_93535_4 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000005118 229.0
HKD2_k127_93535_5 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000002079 151.0
HKD2_k127_93535_6 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000005638 122.0
HKD2_k127_93535_7 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.000000000000005867 80.0
HKD2_k127_93535_8 Belongs to the eIF-2B alpha beta delta subunits family K03680 GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005851,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0019222,GO:0019538,GO:0019899,GO:0030234,GO:0031323,GO:0031326,GO:0032045,GO:0032268,GO:0032991,GO:0034248,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0051020,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0080090,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000001654 61.0
HKD2_k127_93535_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000001673 64.0
HKD2_k127_93564_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 405.0
HKD2_k127_93564_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 308.0
HKD2_k127_9376238_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1019.0
HKD2_k127_9376238_1 Aldehyde dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 287.0
HKD2_k127_9376238_2 Belongs to the glutathione peroxidase family K00432,K20207 - 1.11.1.22,1.11.1.9 0.000000000000000000000000000000000000000000000000000000132 198.0
HKD2_k127_9376238_3 helix_turn_helix multiple antibiotic resistance protein K06075 - - 0.000455 49.0
HKD2_k127_9376947_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 606.0
HKD2_k127_9376947_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 477.0
HKD2_k127_9376947_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 344.0
HKD2_k127_9376947_3 Phosphoribulokinase / Uridine kinase family K00855,K00876 - 2.7.1.19,2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000126 255.0
HKD2_k127_9376947_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000006483 238.0
HKD2_k127_9376947_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000003948 149.0
HKD2_k127_9376947_6 PFAM Phospholipase Carboxylesterase K06999 - - 0.000000202 61.0
HKD2_k127_9376947_7 Transcription factor zinc-finger K09981 - - 0.0004873 46.0
HKD2_k127_9378685_0 Tetratricopeptide repeat - - - 1.767e-235 761.0
HKD2_k127_9378685_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 509.0
HKD2_k127_9378685_10 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.0000000000000000000007732 102.0
HKD2_k127_9378685_11 Right handed beta helix region - - - 0.0000000000000000001031 101.0
HKD2_k127_9378685_12 SpoVT / AbrB like domain - - - 0.00000000004487 66.0
HKD2_k127_9378685_13 chemotaxis protein K03406 - - 0.000001546 60.0
HKD2_k127_9378685_14 Response regulator receiver domain - - - 0.0004861 48.0
HKD2_k127_9378685_2 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 409.0
HKD2_k127_9378685_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 394.0
HKD2_k127_9378685_4 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 393.0
HKD2_k127_9378685_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 309.0
HKD2_k127_9378685_6 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 313.0
HKD2_k127_9378685_7 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000001145 214.0
HKD2_k127_9378685_8 Two component signalling adaptor domain - - - 0.0000000000000000000000000000000000000000000001818 192.0
HKD2_k127_9378685_9 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000000000005504 154.0
HKD2_k127_9381504_0 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 353.0
HKD2_k127_9381504_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 359.0
HKD2_k127_9381504_2 epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 311.0
HKD2_k127_9381504_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000004908 245.0
HKD2_k127_9381504_4 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000009488 200.0
HKD2_k127_9381504_5 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000001008 138.0
HKD2_k127_9381504_6 SCP-2 sterol transfer family - - - 0.000000000000000000000000000002501 124.0
HKD2_k127_9381504_7 cheY-homologous receiver domain - - - 0.0000000000000000000000007696 112.0
HKD2_k127_9381504_9 helix_turn_helix, Lux Regulon - - - 0.0005153 50.0
HKD2_k127_9395102_0 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 436.0
HKD2_k127_9395102_1 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 359.0
HKD2_k127_9395102_2 - - - - 0.00000000000000000000000000000000000000000000000000367 198.0
HKD2_k127_9395102_3 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000005457 188.0
HKD2_k127_9395102_4 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000000000000000001947 140.0
HKD2_k127_9395102_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.00000000000000000000000000000001304 145.0
HKD2_k127_9395102_8 Sel1 domain protein repeat-containing protein K07126 - - 0.0000005735 60.0
HKD2_k127_9406359_0 Carbohydrate-selective porin, OprB family - - - 0.000000000000000000000000000000000000000000000000000000005139 202.0
HKD2_k127_9406359_1 OmpA family K03286 - - 0.0000000000000273 85.0
HKD2_k127_9457167_0 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 450.0
HKD2_k127_9457167_1 Transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' - - - 0.0000000000000000000000000000000000000000007143 162.0
HKD2_k127_9457167_2 - - - - 0.00000000000000000000000000000000000000006712 159.0
HKD2_k127_9457167_3 Flagellar basal body rod K02396 - - 0.000000000000000000000000000000001055 136.0
HKD2_k127_9457167_5 Transposase - - - 0.000000000000000003311 91.0
HKD2_k127_9457167_6 Insulin-induced protein (INSIG) - - - 0.00000007656 66.0
HKD2_k127_9476101_0 TPR repeat - - - 0.000001145 61.0
HKD2_k127_9488295_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 463.0
HKD2_k127_9488295_1 Signal peptide peptidase K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 415.0
HKD2_k127_9488295_2 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005011 283.0
HKD2_k127_9488295_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009509 281.0
HKD2_k127_9488295_4 Nudix hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000001633 211.0
HKD2_k127_9488295_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000003349 221.0
HKD2_k127_9488295_6 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000005728 192.0
HKD2_k127_9488295_7 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000005053 109.0
HKD2_k127_9488295_8 - - - - 0.000000000000000000003388 103.0
HKD2_k127_9488295_9 Forkhead associated domain - - - 0.0000000000657 63.0
HKD2_k127_9510082_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006928,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0010212,GO:0031668,GO:0033554,GO:0034641,GO:0040011,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 489.0
HKD2_k127_9510082_1 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000008966 223.0
HKD2_k127_9510082_2 phosphohistidine phosphatase, SixA K08296 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - 0.000000000000000000001603 101.0
HKD2_k127_9530688_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 302.0
HKD2_k127_9530688_1 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000003874 185.0
HKD2_k127_9530688_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000007928 117.0
HKD2_k127_9530688_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000002449 114.0
HKD2_k127_9530688_4 D-alanyl-D-alanine carboxypeptidase - - - 0.00004969 53.0
HKD2_k127_9533957_0 AcrB/AcrD/AcrF family K07788 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 428.0
HKD2_k127_9533957_1 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 340.0
HKD2_k127_9533957_2 Thioesterase K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000000002703 242.0
HKD2_k127_9533957_3 long-chain fatty acid transport protein K06076 - - 0.0000000000000002658 94.0
HKD2_k127_9533957_4 long-chain fatty acid transporting porin activity K06076 - - 0.0000000005482 72.0
HKD2_k127_9551256_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 432.0
HKD2_k127_9551256_1 LysR substrate binding domain K18297 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 326.0
HKD2_k127_9551256_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K03921,K07052 - 1.14.19.11,1.14.19.2,1.14.19.26,1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 299.0
HKD2_k127_9554319_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000001506 105.0
HKD2_k127_9554319_1 lactoylglutathione lyase activity - - - 0.00000000000000000002164 96.0
HKD2_k127_9558684_0 response regulator K07713 - - 1.046e-209 663.0
HKD2_k127_9558684_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 610.0
HKD2_k127_9558684_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 505.0
HKD2_k127_9558684_3 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 494.0
HKD2_k127_9558684_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 315.0
HKD2_k127_9558684_5 zinc-ribbon domain - - - 0.00000000000000000000000000000000000002995 161.0
HKD2_k127_9558684_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000001244 143.0
HKD2_k127_9558684_7 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000003748 136.0
HKD2_k127_9558684_8 cheY-homologous receiver domain - - - 0.00000000000000001086 98.0
HKD2_k127_9562727_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 460.0
HKD2_k127_9562727_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000002205 222.0
HKD2_k127_9562727_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000001977 158.0
HKD2_k127_9576432_0 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0001857 44.0
HKD2_k127_95876_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000001714 223.0
HKD2_k127_95876_1 Phosphoesterase - - - 0.000000000000000000000000000000000000000000000000005938 199.0
HKD2_k127_95876_3 S-layer homology domain - - - 0.00000000133 70.0
HKD2_k127_9589154_0 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 452.0
HKD2_k127_9589154_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 334.0
HKD2_k127_9589154_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000001073 90.0
HKD2_k127_9599734_0 DnaJ C terminal domain K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 340.0
HKD2_k127_9599734_1 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000002909 248.0
HKD2_k127_9599734_2 - - - - 0.0000000000000000000000000000000000000000084 164.0
HKD2_k127_9599734_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000007135 153.0
HKD2_k127_9599734_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000003386 145.0
HKD2_k127_960145_0 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000003398 246.0
HKD2_k127_960145_1 threonine synthase K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.00000000000000000001258 96.0
HKD2_k127_960145_2 zinc-ribbon domain - - - 0.000004184 54.0
HKD2_k127_9607189_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000006394 183.0
HKD2_k127_9607189_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000001139 118.0
HKD2_k127_9653045_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 363.0
HKD2_k127_9653045_1 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000327 280.0
HKD2_k127_9653045_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000008894 234.0
HKD2_k127_9653045_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000005764 187.0
HKD2_k127_9654358_0 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 404.0
HKD2_k127_9654358_1 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 334.0
HKD2_k127_9654358_10 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000001459 133.0
HKD2_k127_9654358_11 - - - - 0.00000000000000000001759 101.0
HKD2_k127_9654358_12 Phosphotransferase enzyme family - - - 0.000003066 60.0
HKD2_k127_9654358_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001215 284.0
HKD2_k127_9654358_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001098 269.0
HKD2_k127_9654358_4 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000001903 250.0
HKD2_k127_9654358_6 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000003342 206.0
HKD2_k127_9654358_7 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000008542 190.0
HKD2_k127_9654358_8 Adenylate guanylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000483 174.0
HKD2_k127_9654358_9 Belongs to the phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000001781 149.0
HKD2_k127_9663930_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.418e-199 649.0
HKD2_k127_9663930_1 Aldehyde dehydrogenase family K02618,K15514 - 1.2.1.77,1.2.1.91,3.3.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 614.0
HKD2_k127_9663930_10 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000008104 104.0
HKD2_k127_9663930_11 cheY-homologous receiver domain - - - 0.000000000007055 71.0
HKD2_k127_9663930_12 - - - - 0.0000000001314 73.0
HKD2_k127_9663930_13 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000001225 62.0
HKD2_k127_9663930_14 PFAM Protein kinase - - - 0.000001716 60.0
HKD2_k127_9663930_15 Protein conserved in bacteria - - - 0.0005654 52.0
HKD2_k127_9663930_2 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 321.0
HKD2_k127_9663930_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891,K15546 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000007251 233.0
HKD2_k127_9663930_4 hemerythrin HHE cation binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000005006 186.0
HKD2_k127_9663930_5 Dolichol kinase - - - 0.00000000000000000000000000000000000000000000001595 179.0
HKD2_k127_9663930_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000003812 170.0
HKD2_k127_9663930_7 - - - - 0.00000000000000000000000000000000000000007724 156.0
HKD2_k127_9663930_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000001017 112.0
HKD2_k127_9663930_9 lipolytic protein G-D-S-L family - - - 0.00000000000000000000002448 112.0
HKD2_k127_9673325_0 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 585.0
HKD2_k127_9673325_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 342.0
HKD2_k127_9673325_2 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005766 278.0
HKD2_k127_9673325_3 LysM domain - - - 0.0000000000000000001387 103.0
HKD2_k127_9673325_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000001057 96.0
HKD2_k127_9706018_0 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005936 238.0
HKD2_k127_9706018_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000009149 133.0
HKD2_k127_9712388_0 belongs to the thioredoxin family K03671,K05838,K07390,K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 301.0
HKD2_k127_9712388_1 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000005688 211.0
HKD2_k127_9712388_2 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000002118 180.0
HKD2_k127_9712388_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000002615 183.0
HKD2_k127_9712388_4 heat shock protein binding K03686 - - 0.000000000000000000000000001267 113.0
HKD2_k127_9712388_5 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000188 77.0
HKD2_k127_9738734_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 372.0
HKD2_k127_9738734_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000117 269.0
HKD2_k127_9738734_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002586 237.0
HKD2_k127_9738734_4 Tetratricopeptide repeat - - - 0.000001826 60.0
HKD2_k127_9784385_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 315.0
HKD2_k127_9784385_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol - - - 0.00000000000000000000000000000000000000000000000000000000000000000001821 258.0
HKD2_k127_9784385_2 Thioredoxin-like - - - 0.000000000000000000000000000000000000002164 162.0
HKD2_k127_9784385_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000001939 134.0
HKD2_k127_9784385_5 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000003116 85.0
HKD2_k127_9789252_0 Protease prsW family - - - 0.000000000000000000000000000000000000000000000000000000000000000001985 241.0
HKD2_k127_9789252_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000001225 177.0
HKD2_k127_9789252_3 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000001016 68.0
HKD2_k127_9799249_1 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 0.00002074 47.0
HKD2_k127_9799249_2 - - - - 0.0000351 56.0
HKD2_k127_9807328_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 557.0
HKD2_k127_9807328_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 465.0
HKD2_k127_9807328_2 phosphoglycolate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000443 259.0
HKD2_k127_9807328_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000002343 254.0
HKD2_k127_9807328_4 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000003984 203.0
HKD2_k127_9807328_6 N-6 DNA Methylase - - - 0.0000000000000000000008498 99.0
HKD2_k127_9807328_7 - - - - 0.0000000000000001193 83.0
HKD2_k127_9830373_0 Tetratricopeptide repeats - - - 1.249e-319 1065.0
HKD2_k127_9830373_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 498.0
HKD2_k127_9830373_2 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000911 283.0
HKD2_k127_9830373_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000003194 233.0
HKD2_k127_9841802_0 - - - - 0.00000000000000000000000000000000000001459 153.0
HKD2_k127_9855192_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 379.0
HKD2_k127_9855192_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000002971 231.0
HKD2_k127_9855192_2 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000004102 192.0
HKD2_k127_9855192_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000436 160.0
HKD2_k127_9864458_0 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 405.0
HKD2_k127_9864458_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 383.0
HKD2_k127_9864458_2 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001339 280.0
HKD2_k127_9864458_3 Leucine-rich repeat (LRR) protein - - - 0.000000000000000000000000000000000000001622 157.0
HKD2_k127_9884202_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 366.0
HKD2_k127_9884202_1 desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007311 236.0
HKD2_k127_9884202_2 Regulatory protein, MerR - - - 0.000000000000000000000000000000000000000000000000000002295 206.0
HKD2_k127_9884202_3 phospholipase C K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000007621 193.0
HKD2_k127_9884202_4 DGQHR domain - - - 0.0001385 54.0
HKD2_k127_9897696_0 transposition K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 293.0
HKD2_k127_9897696_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000001153 251.0
HKD2_k127_9897696_2 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000001544 106.0
HKD2_k127_9897696_3 Phosphopantetheine attachment site - - - 0.0000000000000004976 89.0
HKD2_k127_9909142_0 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 445.0
HKD2_k127_9909142_1 - - - - 0.00000000000000000000000000000000000047 153.0
HKD2_k127_9909142_2 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000005671 123.0
HKD2_k127_9917448_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 475.0
HKD2_k127_9917448_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000001312 151.0
HKD2_k127_9933478_0 ABC1 family K03688 - - 4.131e-197 628.0
HKD2_k127_9933478_1 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 421.0
HKD2_k127_9933478_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 372.0
HKD2_k127_9934331_0 acyl-CoA dehydrogenase K09456,K20035 - - 1.944e-272 850.0
HKD2_k127_9934331_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 343.0
HKD2_k127_9934331_2 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000009544 181.0
HKD2_k127_9934331_3 - - - - 0.000000000000000000004635 108.0
HKD2_k127_9934331_4 NUDIX domain K12152 - - 0.0000000000000002231 85.0
HKD2_k127_9934331_5 Transcriptional regulator - - - 0.000000000003041 78.0
HKD2_k127_9934331_7 - - - - 0.0000004166 57.0
HKD2_k127_9934331_8 twitching motility protein K02669 - - 0.0001992 50.0
HKD2_k127_9965260_0 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 363.0
HKD2_k127_9965260_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 300.0
HKD2_k127_9965260_2 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003484 254.0
HKD2_k127_9965260_3 Tetratricopeptide repeat - - - 0.000000000000000003064 92.0
HKD2_k127_9980466_0 DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000002829 214.0
HKD2_k127_9983894_0 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004285 272.0
HKD2_k127_9983894_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000005958 230.0
HKD2_k127_9983894_2 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000006625 215.0
HKD2_k127_9983894_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0007338 47.0
HKD2_k127_9995742_0 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000004191 233.0
HKD2_k127_9995742_1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000002917 201.0
HKD2_k127_9995742_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000004021 159.0
HKD2_k127_9995742_3 FR47-like protein K15520 - 2.3.1.189 0.0000000000000000000000005006 115.0
HKD2_k127_9995742_4 unfolded protein binding K06142 - - 0.00000001832 56.0