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Overview

ID MAG01774
Name HKD2_bin.13
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Ktedonobacteria
Order Ktedonobacterales
Family Ktedonobacteraceae
Genus DATAYF01
Species
Assembly information
Completeness (%) 67.88
Contamination (%) 2.71
GC content (%) 52.0
N50 (bp) 3,138
Genome size (bp) 2,841,687

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2553

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10016925_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 599.0
HKD2_k127_10016925_1 dUTP diphosphatase activity K01520,K13038 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000002609 237.0
HKD2_k127_10016925_2 heat shock protein binding K03686,K05516 - - 0.000000000000000000000002609 106.0
HKD2_k127_10036457_0 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 3.313e-286 893.0
HKD2_k127_10056163_0 Transketolase, pyrimidine binding domain K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 368.0
HKD2_k127_10056163_1 PFAM alpha beta hydrolase fold K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000003165 184.0
HKD2_k127_10056163_2 Dodecin K09165 - - 0.0000000000000001843 79.0
HKD2_k127_10062941_0 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000009159 147.0
HKD2_k127_10062941_1 Domain of unknown function (DUF4203) - - - 0.0000000000000000000000000000001471 131.0
HKD2_k127_10062941_2 COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog K03088 - - 0.0000000000000000000000005224 105.0
HKD2_k127_10062941_3 AI-2E family transporter - - - 0.000000000000000000002284 99.0
HKD2_k127_10062941_4 COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog K03088 - - 0.00003569 48.0
HKD2_k127_10067324_0 transposase activity K07483 - - 0.000000000000000000000000000000006364 130.0
HKD2_k127_10067324_1 CHAT domain - - - 0.0000000000000000000001184 104.0
HKD2_k127_10067324_2 Integrase core domain K07497 - - 0.00000000000000000008722 100.0
HKD2_k127_10067582_0 PFAM Dak phosphatase K07030 - - 2.145e-257 804.0
HKD2_k127_10067582_1 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 356.0
HKD2_k127_10067582_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000004469 69.0
HKD2_k127_10067582_12 PFAM DegV family protein - - - 0.0001071 44.0
HKD2_k127_10067582_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 321.0
HKD2_k127_10067582_4 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000000000000000000000000000000000006332 207.0
HKD2_k127_10067582_5 ATP synthesis coupled proton transport K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000004042 199.0
HKD2_k127_10067582_6 Asp23 family, cell envelope-related function - - - 0.000000000000000000000000000000000000000000000000000004824 192.0
HKD2_k127_10067582_7 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000001147 126.0
HKD2_k127_10067582_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000265 93.0
HKD2_k127_10073908_0 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 336.0
HKD2_k127_10073908_1 PFAM small multidrug resistance protein K03297,K11741 - - 0.000002104 50.0
HKD2_k127_10076866_0 PFAM molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 315.0
HKD2_k127_10076866_1 cell adhesion involved in biofilm formation K07004,K12132 - 2.7.11.1 0.00000000000409 78.0
HKD2_k127_10080491_0 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 417.0
HKD2_k127_10080491_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000002143 221.0
HKD2_k127_10080491_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 - 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000002995 192.0
HKD2_k127_10083455_0 FtsZ-dependent cytokinesis K03975,K19302 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0050896,GO:0051301,GO:0071944 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000009859 248.0
HKD2_k127_10083455_1 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.000000000000000001224 86.0
HKD2_k127_10083455_2 Protein of unknown function (DUF664) - - - 0.00000000000004383 79.0
HKD2_k127_10085013_0 CBS domain containing protein K03699 - - 3.846e-204 645.0
HKD2_k127_10085013_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 527.0
HKD2_k127_10085013_2 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 462.0
HKD2_k127_10096880_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1509.0
HKD2_k127_10097755_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1024.0
HKD2_k127_10097755_1 - K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 361.0
HKD2_k127_1010396_0 Putative exonuclease SbcCD, C subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002145 255.0
HKD2_k127_10133933_0 COGs COG3127 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 3.046e-229 724.0
HKD2_k127_10133933_1 COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.000000000000006727 75.0
HKD2_k127_10161345_0 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 531.0
HKD2_k127_10161345_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003278 258.0
HKD2_k127_10161345_2 Belongs to the GPI family K01810 - 5.3.1.9 0.00001537 56.0
HKD2_k127_10171999_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.43e-233 728.0
HKD2_k127_10171999_1 Glycosyltransferase 28 domain K03715 - 2.4.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 602.0
HKD2_k127_10171999_10 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000003953 130.0
HKD2_k127_10171999_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 541.0
HKD2_k127_10171999_4 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 428.0
HKD2_k127_10171999_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 390.0
HKD2_k127_10171999_6 Haloacid dehalogenase domain protein hydrolase, type 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 355.0
HKD2_k127_10171999_7 PFAM Dual specificity protein phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 296.0
HKD2_k127_10171999_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000003319 217.0
HKD2_k127_10174173_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 580.0
HKD2_k127_10174173_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000009539 226.0
HKD2_k127_1023576_0 histidine kinase A domain protein K11527 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 504.0
HKD2_k127_1026257_0 - K07484 - - 0.0000000000000000000000000000000000000000000000000000007956 195.0
HKD2_k127_1026257_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000005637 164.0
HKD2_k127_1028205_0 inorganic diphosphatase activity K15986 - 3.6.1.1 1.408e-233 731.0
HKD2_k127_1028205_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 406.0
HKD2_k127_104073_0 Alkaline phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 512.0
HKD2_k127_104073_1 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007013 256.0
HKD2_k127_104073_2 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000002258 115.0
HKD2_k127_1044543_0 PFAM transferase hexapeptide repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 313.0
HKD2_k127_1044543_2 deacetylase - - - 0.0000000000000000004098 96.0
HKD2_k127_1046489_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 546.0
HKD2_k127_1046489_1 Membrane protein implicated in regulation of membrane protease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000008768 228.0
HKD2_k127_1046489_2 sequence-specific DNA binding K03427 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000003091 198.0
HKD2_k127_1046489_3 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000002769 133.0
HKD2_k127_1047959_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1790.0
HKD2_k127_1047959_1 Ser-tRNA(Ala) hydrolase activity K01872,K07050 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 393.0
HKD2_k127_1047959_2 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000824 254.0
HKD2_k127_1047959_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000001718 85.0
HKD2_k127_1059243_0 - - - - 0.000000000000000000000000000000000000000000000004727 176.0
HKD2_k127_107404_0 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 1.812e-216 676.0
HKD2_k127_107404_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 526.0
HKD2_k127_107404_2 proteolysis K21140 - 3.13.1.6 0.00000000000000000000000000000000000000000000000000000000000004945 216.0
HKD2_k127_107404_3 PFAM thiamineS protein K03636 - - 0.0000000000000000000000000000000000001581 142.0
HKD2_k127_1094795_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 4.888e-200 637.0
HKD2_k127_1094795_1 NADPH:quinone reductase activity K00344 - 1.6.5.5 0.0000002 52.0
HKD2_k127_110299_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 579.0
HKD2_k127_110299_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 462.0
HKD2_k127_110299_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 306.0
HKD2_k127_110299_6 TIGRFAM transposase, IS605 OrfB family, central region K07496 - - 0.0000000000000000000004162 96.0
HKD2_k127_1110748_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 445.0
HKD2_k127_1110748_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 295.0
HKD2_k127_1111874_0 Serine threonine protein kinase K08884 - 2.7.11.1 5.51e-288 900.0
HKD2_k127_1111874_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 6.307e-194 611.0
HKD2_k127_1111874_2 Protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 381.0
HKD2_k127_1111874_3 Protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000002627 79.0
HKD2_k127_1124161_0 Radical SAM domain protein K04070 - 1.97.1.4 3.831e-194 607.0
HKD2_k127_1124161_1 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000008451 134.0
HKD2_k127_1124161_2 pseudouridine synthase activity K06178 - 5.4.99.22 0.000000000000007177 83.0
HKD2_k127_1127667_0 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 507.0
HKD2_k127_1127667_1 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000007994 196.0
HKD2_k127_1127667_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000000000000000000000000496 178.0
HKD2_k127_1142858_0 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 1.509e-220 691.0
HKD2_k127_1142858_1 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000003104 71.0
HKD2_k127_1162980_0 CHAT domain - - - 0.0 1368.0
HKD2_k127_1162980_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 4.013e-223 698.0
HKD2_k127_1162980_2 protein kinase activity - - - 0.000000006787 58.0
HKD2_k127_1166670_0 SMART serine threonine protein kinase - - - 3.477e-218 687.0
HKD2_k127_1173236_0 Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 284.0
HKD2_k127_1173236_1 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009045 272.0
HKD2_k127_1173236_2 regulation of RNA biosynthetic process - - - 0.0000000000000000000000000000000000000000000000001069 179.0
HKD2_k127_1173236_3 Transposase (IS116 IS110 IS902 family) K07486 - - 0.00000174 51.0
HKD2_k127_120249_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004085 267.0
HKD2_k127_120249_1 Two component transcriptional regulator, winged helix family K07669 - - 0.000000000000000000000000000000000000000000000000000000000000000000003186 236.0
HKD2_k127_1215917_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 6.384e-253 786.0
HKD2_k127_1215917_1 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 335.0
HKD2_k127_1215917_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000007366 79.0
HKD2_k127_1220093_0 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 299.0
HKD2_k127_1220093_1 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008585 259.0
HKD2_k127_1220093_2 queuosine metabolic process K04068,K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 1.97.1.4,4.3.99.3 0.0000000000000000000000000000000000000000000006409 167.0
HKD2_k127_1226793_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.374e-210 662.0
HKD2_k127_1226793_1 Serine Threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000001158 248.0
HKD2_k127_1226793_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000003852 158.0
HKD2_k127_122700_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 295.0
HKD2_k127_122700_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000797 170.0
HKD2_k127_122700_3 - - - - 0.0000000002631 63.0
HKD2_k127_122794_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008623 253.0
HKD2_k127_1266123_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 380.0
HKD2_k127_1266123_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000003579 245.0
HKD2_k127_1266123_2 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000001113 90.0
HKD2_k127_1274506_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 2.191e-270 841.0
HKD2_k127_1274506_1 Domain of unknown function (DUF4405) - - - 0.000000000000000000000000000000000000000000001062 173.0
HKD2_k127_1274506_2 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000001318 79.0
HKD2_k127_1275520_0 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 286.0
HKD2_k127_1275520_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000004027 202.0
HKD2_k127_1275520_2 - - - - 0.00000000000000000007511 89.0
HKD2_k127_1281708_0 symporter activity K03307 - - 4.612e-230 723.0
HKD2_k127_1293625_0 lipopolysaccharide transport K22110 - - 0.0 1049.0
HKD2_k127_1293625_1 PFAM Transposase, IS4-like - - - 0.0004293 44.0
HKD2_k127_1308948_0 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 345.0
HKD2_k127_1320166_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 497.0
HKD2_k127_1320166_1 IMP cyclohydrolase activity K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 295.0
HKD2_k127_1320166_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000003115 199.0
HKD2_k127_1320166_3 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000003132 164.0
HKD2_k127_1320166_4 histone H2A K63-linked ubiquitination K21397 - - 0.0000000000000000000000000000003145 129.0
HKD2_k127_13228_0 PFAM metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 469.0
HKD2_k127_13228_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 292.0
HKD2_k127_13228_2 Putative membrane peptidase family (DUF2324) - - - 0.0000000000000000000000000000000000000000519 157.0
HKD2_k127_1326779_0 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 475.0
HKD2_k127_1326779_2 dihydropteroate synthase K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000005855 203.0
HKD2_k127_1326779_3 Transposase, IS605 OrfB family K07496 - - 0.00000000000000000000000000000000000000000000003725 171.0
HKD2_k127_1326779_4 anaphase-promoting complex binding K12132 - 2.7.11.1 0.000000000000000000000000000000000000000008159 158.0
HKD2_k127_1340112_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 592.0
HKD2_k127_1347747_0 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 475.0
HKD2_k127_1347747_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 298.0
HKD2_k127_1358773_0 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002144 268.0
HKD2_k127_1358773_1 Transposase K07492 - - 0.0000000003144 63.0
HKD2_k127_1358773_2 PFAM Transposase DDE domain - - - 0.0008483 42.0
HKD2_k127_1364948_0 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 483.0
HKD2_k127_1364948_1 PFAM DAHP synthetase I KDSA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 474.0
HKD2_k127_1364948_2 PFAM response regulator receiver K22010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 339.0
HKD2_k127_1364948_3 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000002223 177.0
HKD2_k127_1368050_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.986e-208 651.0
HKD2_k127_1368050_1 - K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 415.0
HKD2_k127_1368050_2 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002989 260.0
HKD2_k127_1368050_3 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000000001794 196.0
HKD2_k127_1369256_0 amino acid K14052 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008324,GO:0008519,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015101,GO:0015203,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015489,GO:0015672,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0033554,GO:0034220,GO:0034641,GO:0040011,GO:0042402,GO:0044106,GO:0044237,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051234,GO:0051674,GO:0051716,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072488,GO:0097164,GO:0098655,GO:0098660,GO:0098662,GO:1901564,GO:1901565,GO:1901575,GO:1902047,GO:1902600 - 1.524e-246 770.0
HKD2_k127_1369256_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000005235 168.0
HKD2_k127_1369256_2 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000237 159.0
HKD2_k127_1369256_3 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000000000000001121 141.0
HKD2_k127_1369256_4 endonuclease activity K01409 - 2.3.1.234 0.00000000000000000000000002172 111.0
HKD2_k127_1369256_6 There are 9 addittional ORFs identical to this one - - - 0.000007112 48.0
HKD2_k127_1396112_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1536.0
HKD2_k127_1396112_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 6.384e-308 946.0
HKD2_k127_1401993_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.344e-278 862.0
HKD2_k127_1401993_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 400.0
HKD2_k127_1401993_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000000000009965 229.0
HKD2_k127_1401993_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000001049 198.0
HKD2_k127_1402086_0 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003784 247.0
HKD2_k127_1459900_0 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 371.0
HKD2_k127_1459900_1 PFAM peptidase M55 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006963 273.0
HKD2_k127_1462522_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 427.0
HKD2_k127_1467882_0 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000009067 197.0
HKD2_k127_1467882_1 Protein of unknown function (DUF1211) - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000005448 174.0
HKD2_k127_1467882_2 Regulatory protein, FmdB family - - - 0.000000000000000003832 87.0
HKD2_k127_1467882_4 COGs COG0589 Universal stress protein UspA and related nucleotide-binding protein - - - 0.0000000000252 67.0
HKD2_k127_147405_0 phosphoenolpyruvate synthase K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 520.0
HKD2_k127_1475492_0 glutamate synthase, alpha subunit domain protein K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2070.0
HKD2_k127_1475492_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005932 276.0
HKD2_k127_1475492_2 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0005016 42.0
HKD2_k127_1486112_0 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002875 259.0
HKD2_k127_1493484_0 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 529.0
HKD2_k127_1493484_1 Protein of unknown function (DUF3300) - - - 0.00000000000000000000007244 104.0
HKD2_k127_1493484_2 domain, Protein K00703,K07082 - 2.4.1.21 0.00000000000000003545 91.0
HKD2_k127_1493484_3 Sulfatase K01130 - 3.1.6.1 0.000000001043 59.0
HKD2_k127_1501350_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 556.0
HKD2_k127_1501350_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 348.0
HKD2_k127_1501350_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 304.0
HKD2_k127_1501502_0 tail collar domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 320.0
HKD2_k127_1501502_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002245 284.0
HKD2_k127_1510457_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001523 276.0
HKD2_k127_1510457_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001905 257.0
HKD2_k127_1517062_0 Succinylglutamate desuccinylase aspartoacylase - - - 0.000000000000000000000000000000000000000000000000000002327 203.0
HKD2_k127_151906_0 anaphase-promoting complex binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 481.0
HKD2_k127_1523454_0 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) K00164 - 1.2.4.2 0.0 1395.0
HKD2_k127_1524144_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 379.0
HKD2_k127_1524144_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K12955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 300.0
HKD2_k127_1528042_0 - K06198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 479.0
HKD2_k127_1528042_1 histidine kinase A domain protein K07646 - 2.7.13.3 0.0000000000002048 74.0
HKD2_k127_1528735_0 - - - - 0.000000000000000000000000000000000000000000000000000000126 198.0
HKD2_k127_1528735_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000004015 195.0
HKD2_k127_1528735_2 Short repeat of unknown function (DUF308) - - - 0.00002583 53.0
HKD2_k127_1534237_0 Isocitrate/isopropylmalate dehydrogenase - - - 4.529e-250 778.0
HKD2_k127_1534237_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000004299 236.0
HKD2_k127_1538765_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 4.633e-288 899.0
HKD2_k127_1538765_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 431.0
HKD2_k127_1540048_0 ABC transporter, transmembrane region K06147,K18890 - - 1.888e-253 789.0
HKD2_k127_1561197_0 DNA modification - - - 4.262e-223 707.0
HKD2_k127_1571581_0 Catalase domain protein K03781 - 1.11.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 281.0
HKD2_k127_1571581_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003952 269.0
HKD2_k127_1575581_0 Thiamine pyrophosphate protein TPP binding domain protein K00156,K00158 - 1.2.3.3,1.2.5.1 3.32e-293 908.0
HKD2_k127_1575581_1 Response regulator receiver K07669 - - 0.000000000000000000000000000000000000000000000000000008184 196.0
HKD2_k127_1575581_2 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.00000000000000000000000000000000002828 137.0
HKD2_k127_157889_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 8.137e-270 843.0
HKD2_k127_1589999_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 368.0
HKD2_k127_1589999_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000007484 177.0
HKD2_k127_1591560_0 PFAM DNA mismatch repair protein MutS domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 419.0
HKD2_k127_1591560_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001499 280.0
HKD2_k127_1591560_2 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000007753 138.0
HKD2_k127_1620869_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 497.0
HKD2_k127_1620869_1 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008062 260.0
HKD2_k127_1643529_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 340.0
HKD2_k127_164698_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 410.0
HKD2_k127_164698_1 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000003125 222.0
HKD2_k127_1646998_0 conserved protein (DUF2156) K14205 - 2.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000001167 252.0
HKD2_k127_1648779_0 PFAM ABC transporter related K06147 - - 1.856e-286 890.0
HKD2_k127_1682362_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 304.0
HKD2_k127_1682362_1 pathogenesis K21471,K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000002333 184.0
HKD2_k127_1682362_2 - - - - 0.000000000000000000000000000000000000005827 151.0
HKD2_k127_1704735_0 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 542.0
HKD2_k127_1704735_1 Uricase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 391.0
HKD2_k127_1728292_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000009197 143.0
HKD2_k127_1728292_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000001749 117.0
HKD2_k127_1734175_0 PFAM Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 353.0
HKD2_k127_1734175_1 Transposase - - - 0.00000000000000000000000000000006349 127.0
HKD2_k127_1734175_2 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.0000000000000000000000001378 109.0
HKD2_k127_1737365_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 444.0
HKD2_k127_1737365_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 376.0
HKD2_k127_1737365_2 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000002781 230.0
HKD2_k127_1755310_0 collagen metabolic process K08677 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003503 277.0
HKD2_k127_1755310_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000003436 123.0
HKD2_k127_1767326_0 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000547 551.0
HKD2_k127_1767326_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 497.0
HKD2_k127_1767326_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 397.0
HKD2_k127_1767326_3 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000001467 256.0
HKD2_k127_1767574_0 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 413.0
HKD2_k127_1767574_1 Mo-molybdopterin cofactor metabolic process K03636 - - 0.00000000000000000000000004068 111.0
HKD2_k127_177031_0 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 1.804e-278 859.0
HKD2_k127_177031_1 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000399 219.0
HKD2_k127_177031_2 AAA domain (dynein-related subfamily) - - - 0.000000000000000807 79.0
HKD2_k127_1774824_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000002131 95.0
HKD2_k127_1774824_1 Acetyltransferase (GNAT) domain - - - 0.00000007274 57.0
HKD2_k127_1776489_0 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 291.0
HKD2_k127_1777333_0 PFAM alpha beta hydrolase fold K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 461.0
HKD2_k127_1777333_1 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000004786 179.0
HKD2_k127_1777333_2 polyhydroxyalkanoic acid synthase, PhaR subunit - - - 0.000000000000000000001548 100.0
HKD2_k127_1778632_0 Lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000008678 172.0
HKD2_k127_1778632_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000001436 167.0
HKD2_k127_1809941_0 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 400.0
HKD2_k127_1809941_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 317.0
HKD2_k127_1809941_2 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000000000000000000000000000001318 170.0
HKD2_k127_1826707_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 600.0
HKD2_k127_1826707_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 416.0
HKD2_k127_1826707_2 Glycogen debranching enzyme N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008697 256.0
HKD2_k127_1846144_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.00000000000000000000000000004659 119.0
HKD2_k127_1852581_0 signal-transduction protein containing cAMP-binding and CBS domains K00384 - 1.8.1.9 1.949e-279 872.0
HKD2_k127_1852581_1 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 330.0
HKD2_k127_1853015_0 Putative exonuclease SbcCD, C subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003614 271.0
HKD2_k127_1853015_1 Domain of unknown function (DUF4194) - - - 0.00000000000000000000000000000000000102 148.0
HKD2_k127_1853015_2 Protein of unknown function (DUF3375) - - - 0.000000004289 63.0
HKD2_k127_1861703_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 427.0
HKD2_k127_1861703_1 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 341.0
HKD2_k127_1861703_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000003232 252.0
HKD2_k127_1869419_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 5.085e-296 920.0
HKD2_k127_1869419_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 290.0
HKD2_k127_1869419_2 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000001473 177.0
HKD2_k127_1869419_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000001618 154.0
HKD2_k127_1902416_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008827 567.0
HKD2_k127_1902416_1 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 460.0
HKD2_k127_1902416_2 hydrolase activity, acting on ester bonds K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 405.0
HKD2_k127_1902416_3 Belongs to the glycosyl hydrolase 3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002282 261.0
HKD2_k127_1913922_0 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 388.0
HKD2_k127_1913922_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 358.0
HKD2_k127_1913922_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000002554 218.0
HKD2_k127_1921704_0 ATPase involved in DNA repair K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 407.0
HKD2_k127_1928169_0 PFAM Transposase - - - 0.00000000000000000000000000000000000000000000000000000000002716 210.0
HKD2_k127_1928169_1 Transposase K07492 - - 0.00000000000000000000000000000000000000000000001822 173.0
HKD2_k127_1928169_2 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000002036 102.0
HKD2_k127_1928169_4 PFAM Uncharacterised protein family UPF0150 - - - 0.00000006948 54.0
HKD2_k127_1928169_5 serine-type peptidase activity K06889 - - 0.000328 53.0
HKD2_k127_1930723_0 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 349.0
HKD2_k127_1930723_2 Pfam:DUF59 - - - 0.0000000000000000000000000000000000000000000000000001266 187.0
HKD2_k127_1931094_0 PFAM conserved K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 484.0
HKD2_k127_1931094_1 PFAM O-antigen polymerase - - - 0.0000000000002048 71.0
HKD2_k127_1935138_0 type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 432.0
HKD2_k127_1935138_1 PFAM Phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 340.0
HKD2_k127_1935138_2 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.00000004052 54.0
HKD2_k127_1944239_0 Alanine racemase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 576.0
HKD2_k127_1944239_1 D-arabinono-1,4-lactone oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 308.0
HKD2_k127_1945090_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 481.0
HKD2_k127_1945090_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 473.0
HKD2_k127_1945090_2 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 353.0
HKD2_k127_1945090_3 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K16422 - 1.1.2.3,1.1.3.46 0.00000000000000000000000000000000000000000004469 164.0
HKD2_k127_1968191_0 PFAM glycosyl transferase, family 51 - - - 5.847e-249 779.0
HKD2_k127_1972612_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 592.0
HKD2_k127_1972612_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000008578 208.0
HKD2_k127_197437_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 562.0
HKD2_k127_197437_1 DNA-dependent DNA replication K02315 - - 0.0000000000000000000000000000000000000000000003095 179.0
HKD2_k127_1984594_0 COG Phage tail sheath protein FI K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004328 264.0
HKD2_k127_1984594_1 Phage tail sheath protein subtilisin-like domain K06907 - - 0.00000000000000000000000000000000000000000000000000000000000006658 230.0
HKD2_k127_1984594_2 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000005997 181.0
HKD2_k127_199697_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206,K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 356.0
HKD2_k127_199697_1 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000003126 213.0
HKD2_k127_2001920_0 Belongs to the RtcB family K14415 - 6.5.1.3 8.744e-253 786.0
HKD2_k127_2001920_1 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 486.0
HKD2_k127_2001920_2 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000000002764 177.0
HKD2_k127_2006665_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000004932 81.0
HKD2_k127_2010846_0 binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009806 255.0
HKD2_k127_2010846_1 PFAM binding-protein-dependent transport systems inner membrane component K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000326 240.0
HKD2_k127_2010846_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000004485 113.0
HKD2_k127_2011555_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 361.0
HKD2_k127_2011555_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003771 252.0
HKD2_k127_2022589_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 359.0
HKD2_k127_2023960_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 361.0
HKD2_k127_2023960_1 choline dehydrogenase activity - - - 0.00000000000000000000000000000000000000001525 172.0
HKD2_k127_2026263_0 - K18320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 388.0
HKD2_k127_2030811_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 323.0
HKD2_k127_2030811_1 PFAM transferase hexapeptide repeat containing protein K16881 - 2.7.7.13,5.4.2.8 0.0000000000000003667 78.0
HKD2_k127_2036234_0 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000002278 92.0
HKD2_k127_2039396_0 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 522.0
HKD2_k127_2039396_1 - - - - 0.00000000002643 64.0
HKD2_k127_2048268_1 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 362.0
HKD2_k127_2048768_0 PFAM copper resistance protein CopC K14166 - - 0.00000000000000000000000000000000000000000000000000000000000003904 224.0
HKD2_k127_2048768_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism - - - 0.000000000000000000000000002504 111.0
HKD2_k127_2053708_0 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 588.0
HKD2_k127_2057874_0 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 421.0
HKD2_k127_2057874_1 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001788 276.0
HKD2_k127_2057874_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001071 258.0
HKD2_k127_2057874_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00000000000000000000000000000000000000000000000000000000002353 212.0
HKD2_k127_2057874_4 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000000000000002069 147.0
HKD2_k127_2057874_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000000001237 130.0
HKD2_k127_2057874_6 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000007515 110.0
HKD2_k127_206196_0 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 341.0
HKD2_k127_206196_1 PFAM Maf family protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 299.0
HKD2_k127_206196_2 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000192 215.0
HKD2_k127_2066130_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 518.0
HKD2_k127_2076952_0 TIGRFAM 6-phosphogluconate dehydrogenase (decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 409.0
HKD2_k127_2110432_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 587.0
HKD2_k127_2110432_1 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 565.0
HKD2_k127_2110432_2 COGs COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 436.0
HKD2_k127_2110432_3 COGs COG0601 ABC-type dipeptide oligopeptide nickel transport systems permease components K02033,K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 312.0
HKD2_k127_2110727_0 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 421.0
HKD2_k127_2114698_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 288.0
HKD2_k127_2114698_1 transposition, DNA-mediated - - - 0.00000000000000000002347 92.0
HKD2_k127_2120011_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 2.363e-248 772.0
HKD2_k127_2120011_1 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 560.0
HKD2_k127_2120011_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 516.0
HKD2_k127_2120011_3 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 394.0
HKD2_k127_2120011_4 2 iron, 2 sulfur cluster binding K03518,K07302 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000103 266.0
HKD2_k127_2120011_5 COGs COG3316 Transposase and inactivated derivatives - - - 0.00000000000000000232 88.0
HKD2_k127_213125_0 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 251.0
HKD2_k127_2134027_0 nitrite transmembrane transporter activity K02575 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 337.0
HKD2_k127_2134027_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000194 206.0
HKD2_k127_2136932_0 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 404.0
HKD2_k127_214298_0 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 436.0
HKD2_k127_214298_1 PFAM amine oxidase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000002684 73.0
HKD2_k127_2199112_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1659.0
HKD2_k127_2199112_1 protein deglycation K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000004986 231.0
HKD2_k127_2219384_0 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 387.0
HKD2_k127_2219384_1 PFAM regulatory protein, ArsR K21903 - - 0.000000000000000000000000000000000000000000000000944 179.0
HKD2_k127_2243687_0 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 511.0
HKD2_k127_2243687_1 glucan 1,4-alpha-glucosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 364.0
HKD2_k127_2243687_3 GYD domain - - - 0.000000000000008823 74.0
HKD2_k127_224392_0 PFAM peptidase S16 lon domain protein K07157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 259.0
HKD2_k127_224392_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000002049 244.0
HKD2_k127_2245506_0 Arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 497.0
HKD2_k127_2245506_1 pseudouridine synthase activity K06178 - 5.4.99.22 0.0000002191 57.0
HKD2_k127_2250454_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 366.0
HKD2_k127_2250454_2 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000007308 50.0
HKD2_k127_2251411_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 574.0
HKD2_k127_2251411_1 TIGRFAM membrane-associated zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 421.0
HKD2_k127_2251411_2 - - - - 0.0000000000000000009219 85.0
HKD2_k127_2288380_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 518.0
HKD2_k127_2288380_1 Belongs to the arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 454.0
HKD2_k127_2288380_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006335 265.0
HKD2_k127_2288380_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000995 194.0
HKD2_k127_2288380_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000009392 83.0
HKD2_k127_2300038_0 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 348.0
HKD2_k127_2300038_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.0000000000000000000000000000000000000000000000007205 182.0
HKD2_k127_2300038_2 PFAM Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000002428 147.0
HKD2_k127_2300038_3 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.00000000000000000000000000001525 122.0
HKD2_k127_2300038_4 - - - - 0.0003034 46.0
HKD2_k127_2300173_0 aminopeptidase activity K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 515.0
HKD2_k127_2300173_1 - K07484 - - 0.000000000000000000000003435 102.0
HKD2_k127_231657_0 cell redox homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 469.0
HKD2_k127_231657_1 PFAM diacylglycerol kinase catalytic region - - - 0.000000000000000000000000000000000000000000000000003798 187.0
HKD2_k127_2317148_0 Domain of unknown function DUF87 K06915 - - 2.432e-311 960.0
HKD2_k127_2317148_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 355.0
HKD2_k127_2317148_2 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002185 243.0
HKD2_k127_2326559_0 ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 552.0
HKD2_k127_2326559_1 PFAM transposase, IS4 family protein - - - 0.000000003335 57.0
HKD2_k127_2338893_0 DSHCT K03727 - - 0.0 1069.0
HKD2_k127_2338893_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 481.0
HKD2_k127_2345762_0 B-1 B cell differentiation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000454 266.0
HKD2_k127_2345762_1 PFAM ABC transporter related K06158 - - 0.00004851 46.0
HKD2_k127_2363007_0 Magnesium chelatase, subunit ChlI K07391 - - 3.382e-200 636.0
HKD2_k127_2363007_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 482.0
HKD2_k127_2363007_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 353.0
HKD2_k127_2364627_0 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 342.0
HKD2_k127_2364627_1 transmembrane transporter activity K16783,K16785 - - 0.000000000000000000000000000000000000000006704 158.0
HKD2_k127_2364627_2 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000006963 139.0
HKD2_k127_2370582_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000004093 164.0
HKD2_k127_2370582_1 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000882 162.0
HKD2_k127_2370582_2 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K09971 - - 0.000000000000000000000000000000000000007289 147.0
HKD2_k127_2370582_3 Transposase, IS605 OrfB family K07496 - - 0.0000000000000000000001406 103.0
HKD2_k127_2384220_0 Fibronectin-binding A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 336.0
HKD2_k127_2384220_1 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000001331 188.0
HKD2_k127_2385121_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 6.317e-199 625.0
HKD2_k127_2385121_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000008573 213.0
HKD2_k127_2385121_2 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000131 65.0
HKD2_k127_2388468_0 LURP-one-related - - - 0.0000000000000000000000000000000000000000000000000001851 191.0
HKD2_k127_2388468_1 LURP-one-related - - - 0.0000000000000000000000000000000000000000000005243 172.0
HKD2_k127_2388468_2 transcriptional regulator, LuxR family - - - 0.00000000000000001429 83.0
HKD2_k127_2392588_0 PFAM copper resistance protein CopC K14166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 388.0
HKD2_k127_2392588_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 317.0
HKD2_k127_2414225_0 PFAM transferase hexapeptide repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002078 230.0
HKD2_k127_2414225_1 cysteine-type peptidase activity K21471 - - 0.0000000000000000000000000000000000000000000000000000131 192.0
HKD2_k127_2414225_2 response to copper ion K07156,K14166 - - 0.0000000000000000000000000000008181 125.0
HKD2_k127_2425160_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 435.0
HKD2_k127_2425160_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 295.0
HKD2_k127_2425160_2 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000159 262.0
HKD2_k127_2425160_3 GMC oxidoreductase - - - 0.0000000000000000000758 90.0
HKD2_k127_2425160_4 COGs COG3387 Glucoamylase and related glycosyl hydrolase K07190 - - 0.00000009584 54.0
HKD2_k127_2437734_0 PFAM glycosyl transferase, family 51 - - - 9.461e-291 919.0
HKD2_k127_2437734_1 DDE superfamily endonuclease K07494 - - 0.00002976 46.0
HKD2_k127_2439103_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000001677 216.0
HKD2_k127_2453859_0 Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 503.0
HKD2_k127_2477038_0 PFAM Mu transposase, C-terminal K07497 - - 0.000000000000000000000000000000012 130.0
HKD2_k127_2477038_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000001825 67.0
HKD2_k127_248775_0 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003866 265.0
HKD2_k127_248775_1 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000004288 188.0
HKD2_k127_248775_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000006272 183.0
HKD2_k127_248775_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000000002126 160.0
HKD2_k127_248775_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.00006318 45.0
HKD2_k127_2499630_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 595.0
HKD2_k127_2499630_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 499.0
HKD2_k127_2499630_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002655 240.0
HKD2_k127_2499630_3 Protein of unknown function (DUF1211) - - - 0.00003355 52.0
HKD2_k127_2507040_0 PFAM FAD linked oxidase domain protein K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 366.0
HKD2_k127_2507483_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 463.0
HKD2_k127_2507483_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000002373 79.0
HKD2_k127_2512660_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 4.541e-232 722.0
HKD2_k127_2512660_1 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000002866 177.0
HKD2_k127_2514909_0 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000005613 166.0
HKD2_k127_252593_0 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000001967 226.0
HKD2_k127_2540705_0 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 460.0
HKD2_k127_2540705_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000699 252.0
HKD2_k127_2540779_0 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 396.0
HKD2_k127_2540779_1 PFAM diacylglycerol kinase catalytic region - - - 0.00000000000000000000000000000000000000000000003487 175.0
HKD2_k127_2552375_0 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003416 245.0
HKD2_k127_2552375_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002797 217.0
HKD2_k127_2558716_0 PFAM amidohydrolase 2 K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 469.0
HKD2_k127_2558716_1 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 365.0
HKD2_k127_2558716_2 PFAM MULE transposase, conserved domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 313.0
HKD2_k127_2558716_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000001824 225.0
HKD2_k127_2558716_5 PFAM MULE transposase, conserved domain - - - 0.000000000000000000000000000000000000000000001659 169.0
HKD2_k127_2566918_0 PFAM LOR SDH bifunctional enzyme conserved region - - - 2.943e-197 625.0
HKD2_k127_2566918_1 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003089 250.0
HKD2_k127_2593211_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.74e-297 916.0
HKD2_k127_2593211_1 Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000000000000000000000000000000000000000002634 175.0
HKD2_k127_2596264_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 1.149e-305 941.0
HKD2_k127_2620579_0 histidine kinase A domain protein - - - 0.00000000000000000000000000002454 119.0
HKD2_k127_2620579_1 COGs COG0589 Universal stress protein UspA and related nucleotide-binding protein - - - 0.00000000000000000000000000004167 126.0
HKD2_k127_262162_0 N-4 methylation of cytosine K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 436.0
HKD2_k127_262162_1 - - - - 0.000000000000000000000000011 111.0
HKD2_k127_262162_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000009091 61.0
HKD2_k127_262282_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 1.126e-271 845.0
HKD2_k127_262282_1 PFAM aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 565.0
HKD2_k127_2635680_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.109e-197 620.0
HKD2_k127_2643023_0 PFAM glycosyl transferase, family 51 K05365,K05367 - 2.4.1.129,3.4.16.4 1.401e-263 842.0
HKD2_k127_2643023_1 PFAM regulatory protein, MerR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 316.0
HKD2_k127_2657464_0 protein kinase activity - - - 5.196e-273 850.0
HKD2_k127_2657464_1 peptidyl-tyrosine sulfation - - - 6.433e-213 675.0
HKD2_k127_2657464_2 methionyl-tRNA aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 2.024e-195 617.0
HKD2_k127_2660235_0 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 521.0
HKD2_k127_2660235_2 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 298.0
HKD2_k127_2673555_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000001685 179.0
HKD2_k127_2675243_0 PFAM UvrD REP helicase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 441.0
HKD2_k127_2675243_1 PFAM ABC transporter related K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 355.0
HKD2_k127_2675243_2 PFAM ABC transporter related K16784,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 351.0
HKD2_k127_2675243_4 transmembrane transporter activity K16785,K16786,K16787 - - 0.00000000000000000000009857 105.0
HKD2_k127_2675243_5 transmembrane transporter activity K16785,K16786,K16787 - - 0.000000000000002829 80.0
HKD2_k127_2675243_6 PFAM UvrD REP helicase - - - 0.00000000000007797 73.0
HKD2_k127_2678146_0 homoserine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007752 285.0
HKD2_k127_2678146_1 Luciferase-like monooxygenase - - - 0.00002182 49.0
HKD2_k127_2683024_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0 1091.0
HKD2_k127_2683024_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 423.0
HKD2_k127_2683024_2 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 415.0
HKD2_k127_2683024_3 PFAM diacylglycerol kinase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 364.0
HKD2_k127_2683024_4 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 349.0
HKD2_k127_2697724_0 Putative nucleotide-binding of sugar-metabolising enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 381.0
HKD2_k127_2697724_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000002239 201.0
HKD2_k127_2697724_2 Ketose-bisphosphate aldolase K08302 - 4.1.2.40 0.0000000000000000000000003325 110.0
HKD2_k127_2708597_0 PFAM GAF domain protein K01628,K03406,K21009 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 308.0
HKD2_k127_2708597_1 cyclic-guanylate-specific phosphodiesterase activity - - - 0.00000000000000000000000000000000000000000000000000001202 196.0
HKD2_k127_2712832_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 340.0
HKD2_k127_2712832_1 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 287.0
HKD2_k127_2712832_2 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000004367 191.0
HKD2_k127_2721940_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.428e-260 825.0
HKD2_k127_2721940_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 417.0
HKD2_k127_2721940_2 PFAM FIST C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 313.0
HKD2_k127_2721940_3 TRANSCRIPTIONal - - - 0.0000000000000000000000000000000000002691 143.0
HKD2_k127_2750149_0 Serine threonine protein kinase - - - 3.572e-270 859.0
HKD2_k127_2750149_1 Serine threonine protein kinase K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 259.0
HKD2_k127_2769555_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 8.12e-226 721.0
HKD2_k127_2769555_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 447.0
HKD2_k127_2769555_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000002903 133.0
HKD2_k127_2769555_3 YbaB/EbfC DNA-binding family K09747 - - 0.0000000000000000000000000000000392 126.0
HKD2_k127_2773307_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01537,K12952 - 3.6.3.2,3.6.3.8 1.434e-241 771.0
HKD2_k127_2773307_1 FMN-dependent dehydrogenase - - - 0.00000000000000004771 82.0
HKD2_k127_2791296_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 470.0
HKD2_k127_2791296_1 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 393.0
HKD2_k127_2791296_2 - - - - 0.0000000000000000000000000000000000000000000000000000000009927 201.0
HKD2_k127_2795291_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 1.386e-224 706.0
HKD2_k127_2795291_1 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 499.0
HKD2_k127_2795291_2 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001282 233.0
HKD2_k127_2795291_3 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.00000000000000000000000000000000000000000007328 168.0
HKD2_k127_2815364_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 587.0
HKD2_k127_2815364_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000002137 189.0
HKD2_k127_2821976_0 Predicted membrane protein (DUF2079) - - - 3.557e-242 769.0
HKD2_k127_2821976_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 360.0
HKD2_k127_2821976_3 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000001718 133.0
HKD2_k127_2821976_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000001864 94.0
HKD2_k127_2828609_0 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865 539.0
HKD2_k127_2828609_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 377.0
HKD2_k127_2849089_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000175 210.0
HKD2_k127_2849089_1 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000009616 181.0
HKD2_k127_2849089_2 tRNA 3'-trailer cleavage - - - 0.000000000000000003335 85.0
HKD2_k127_2855774_0 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 524.0
HKD2_k127_2855774_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 328.0
HKD2_k127_2855774_2 Lipoate-protein ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 309.0
HKD2_k127_2855774_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007964 249.0
HKD2_k127_2855774_4 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000001207 206.0
HKD2_k127_2855774_5 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000004698 192.0
HKD2_k127_2855774_6 PFAM diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000007331 151.0
HKD2_k127_2855774_7 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000005242 89.0
HKD2_k127_2858743_1 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 325.0
HKD2_k127_2858743_3 DDE superfamily endonuclease - - - 0.000000000176 61.0
HKD2_k127_2859286_0 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000006432 173.0
HKD2_k127_2859286_1 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000000003408 152.0
HKD2_k127_2859286_2 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.000000000000000000000000000000000003345 139.0
HKD2_k127_2861344_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 6.783e-222 695.0
HKD2_k127_2861344_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 431.0
HKD2_k127_2861344_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000002355 205.0
HKD2_k127_2872011_0 Potential Queuosine, Q, salvage protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 442.0
HKD2_k127_2872011_1 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 405.0
HKD2_k127_2873637_0 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 418.0
HKD2_k127_2873637_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000321 177.0
HKD2_k127_2876094_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 6.86e-316 981.0
HKD2_k127_2876094_1 AMP-binding enzyme K01912 - 6.2.1.30 6.306e-204 641.0
HKD2_k127_2876094_2 Alkaline phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001458 261.0
HKD2_k127_2878783_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 1.415e-208 655.0
HKD2_k127_2878783_1 glycosyl transferase family - - - 0.0000000000009603 79.0
HKD2_k127_2882118_0 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 321.0
HKD2_k127_2882118_1 PFAM Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 315.0
HKD2_k127_2882118_3 Protein of unknown function (DUF3054) - - - 0.00000109 53.0
HKD2_k127_2888752_0 PFAM Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 365.0
HKD2_k127_2888752_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000001905 144.0
HKD2_k127_2892661_0 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 382.0
HKD2_k127_2892661_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 296.0
HKD2_k127_2892661_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000002206 239.0
HKD2_k127_2900310_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 7.355e-281 880.0
HKD2_k127_2900310_1 PFAM Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 608.0
HKD2_k127_2905049_0 PFAM FAD linked oxidase domain protein - - - 1.524e-216 679.0
HKD2_k127_2905049_1 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 363.0
HKD2_k127_2905049_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000001974 59.0
HKD2_k127_2908384_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 595.0
HKD2_k127_2908384_1 PFAM phenylacetic acid catabolic family protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 580.0
HKD2_k127_2908384_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 481.0
HKD2_k127_2908384_3 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 473.0
HKD2_k127_2908384_4 PFAM phenylacetic acid catabolic family protein K02611 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 378.0
HKD2_k127_2908384_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000181 234.0
HKD2_k127_2908384_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005488 226.0
HKD2_k127_2908384_7 Pfam:DUF59 K02612 - - 0.0000000000000000000000000000000000000000000000000000004198 195.0
HKD2_k127_2908384_8 - - - - 0.00000000000000000000000000001327 119.0
HKD2_k127_2914643_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.101e-310 957.0
HKD2_k127_2914643_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000002486 105.0
HKD2_k127_2922008_0 ATPase activity K02017,K02018,K03750,K15497 - 2.10.1.1,3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 416.0
HKD2_k127_2922819_0 - - - - 0.00001778 53.0
HKD2_k127_29258_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000005122 239.0
HKD2_k127_29258_2 ACT domain K09707 - - 0.000000000000000000000000000000000000000000000000001774 185.0
HKD2_k127_2944249_0 cytochrome c oxidase K02351,K02862 - - 0.000000000000000000000000000000000000000000000000000000000000007481 224.0
HKD2_k127_2944817_0 phosphatidylinositol metabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 334.0
HKD2_k127_2944817_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000001258 79.0
HKD2_k127_2945155_0 NYN domain - - - 2.968e-198 626.0
HKD2_k127_2945155_1 PFAM helix-turn-helix HxlR type - - - 0.0000000000000000000000000000000000000000000000002828 177.0
HKD2_k127_2945155_2 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000731 153.0
HKD2_k127_2946731_0 dUTP biosynthetic process K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 388.0
HKD2_k127_2946731_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000001187 245.0
HKD2_k127_2946731_2 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.000000000000000000009227 93.0
HKD2_k127_2948155_0 PFAM binding-protein-dependent transport systems inner membrane component K02026,K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 372.0
HKD2_k127_2948155_1 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 332.0
HKD2_k127_2969212_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000002395 264.0
HKD2_k127_297894_0 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000002056 216.0
HKD2_k127_297894_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000001252 211.0
HKD2_k127_2989118_0 TIGRFAM metal dependent phophohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 304.0
HKD2_k127_2989118_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000000001909 110.0
HKD2_k127_2989118_3 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000001059 57.0
HKD2_k127_2989118_4 DNA excision K02806 - - 0.000002064 51.0
HKD2_k127_2989118_5 Belongs to the 'phage' integrase family - - - 0.00002134 52.0
HKD2_k127_3000581_0 PFAM GAF domain protein K01628,K03406,K21009 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000001129 229.0
HKD2_k127_3000581_1 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000002199 215.0
HKD2_k127_3002311_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 2.589e-195 614.0
HKD2_k127_3002311_1 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 445.0
HKD2_k127_3002311_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 341.0
HKD2_k127_3003317_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 402.0
HKD2_k127_3003317_1 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 311.0
HKD2_k127_3004243_0 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 350.0
HKD2_k127_3011531_0 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 491.0
HKD2_k127_3011531_1 Pfam:Methyltransf_26 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 454.0
HKD2_k127_3032148_0 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001111 260.0
HKD2_k127_3032148_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000002117 122.0
HKD2_k127_3032148_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000007319 115.0
HKD2_k127_3039079_0 PFAM CobB CobQ domain protein glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 431.0
HKD2_k127_3039079_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0004335 46.0
HKD2_k127_3039079_2 Phosphodiester glycosidase - - - 0.0009645 43.0
HKD2_k127_304529_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 544.0
HKD2_k127_304529_1 Ndr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 341.0
HKD2_k127_304529_2 - - - - 0.000000000000000000000002026 109.0
HKD2_k127_3047185_0 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 392.0
HKD2_k127_3047185_1 PFAM ABC transporter related K01990 - - 0.000000000000000009972 83.0
HKD2_k127_3047185_2 PFAM Transposase IS116 IS110 IS902 family - - - 0.000000000007102 69.0
HKD2_k127_3050733_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.68e-232 723.0
HKD2_k127_3050733_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 593.0
HKD2_k127_3050733_2 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003683 275.0
HKD2_k127_3050733_4 Cell division protein FtsQ K03589 - - 0.0000000000004474 72.0
HKD2_k127_3060776_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 313.0
HKD2_k127_3060776_1 Heat induced stress protein YflT - - - 0.000000000000000000000000000003311 131.0
HKD2_k127_3075710_0 PFAM O-antigen polymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 410.0
HKD2_k127_3075710_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 306.0
HKD2_k127_3075710_2 - - - - 0.0000000203 56.0
HKD2_k127_3095167_0 Belongs to the glycosyl hydrolase 57 family K01176,K07405 - 3.2.1.1 2.867e-235 734.0
HKD2_k127_3095167_1 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 421.0
HKD2_k127_3110789_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1376.0
HKD2_k127_3115585_0 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 2.567e-228 713.0
HKD2_k127_3115585_1 phosphatidylinositol metabolic process - - - 0.00000005125 57.0
HKD2_k127_3117351_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 7.557e-199 624.0
HKD2_k127_3117351_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 604.0
HKD2_k127_3117351_2 AAA domain - - - 0.00000000000000000000000000000000000000000000004446 174.0
HKD2_k127_3117351_3 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000001963 169.0
HKD2_k127_3117351_4 Protein of unknown function (DUF448) K07742 - - 0.0000000000000000000000000000000000002035 143.0
HKD2_k127_3117351_5 Acetyltransferase (GNAT) family - - - 0.000000000000000009543 84.0
HKD2_k127_3117351_6 CBS domain containing protein K03699 - - 0.00000000000005867 73.0
HKD2_k127_3138464_0 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 491.0
HKD2_k127_3138464_1 PFAM CoA-binding domain protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001808 254.0
HKD2_k127_3138464_2 - - - - 0.0000000000000000000000000000000000000000000001013 177.0
HKD2_k127_3138464_3 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000001724 94.0
HKD2_k127_3138464_4 - - - - 0.000000001233 61.0
HKD2_k127_3139503_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 305.0
HKD2_k127_3139503_1 helix_turn_helix, Lux Regulon - - - 0.00000001245 58.0
HKD2_k127_3177690_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 605.0
HKD2_k127_3177690_1 COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.00000000000000000000000000000000000000000000001585 173.0
HKD2_k127_3177690_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000007844 74.0
HKD2_k127_3209873_0 methyltransferase activity K21377 - 2.1.1.302 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 436.0
HKD2_k127_3209873_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 302.0
HKD2_k127_3211280_0 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 287.0
HKD2_k127_3211280_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000004505 217.0
HKD2_k127_3216231_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.2e-236 738.0
HKD2_k127_3219761_0 PFAM GAF domain protein - - - 5.799e-300 934.0
HKD2_k127_3219761_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K21062 - 3.5.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 368.0
HKD2_k127_3219761_2 heat shock protein binding K03686,K05801,K17867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 287.0
HKD2_k127_324972_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 2.567e-228 713.0
HKD2_k127_324972_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 319.0
HKD2_k127_3250451_0 Pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 1.195e-247 771.0
HKD2_k127_3250451_1 Polysaccharide deacetylase - - - 0.0000000000000000000000164 107.0
HKD2_k127_326039_0 Nacht domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 382.0
HKD2_k127_326039_2 - - - - 0.0000000000000000744 85.0
HKD2_k127_326039_3 Helix-turn-helix domain - - - 0.00000008084 56.0
HKD2_k127_326436_0 SMART HNH nuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 297.0
HKD2_k127_326436_1 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000004556 130.0
HKD2_k127_3264656_0 PFAM ABC transporter related K06158 - - 7.407e-277 862.0
HKD2_k127_3271043_0 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 550.0
HKD2_k127_3271043_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002072 254.0
HKD2_k127_3272738_0 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 319.0
HKD2_k127_3272738_1 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000001379 230.0
HKD2_k127_3276233_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 4.259e-230 717.0
HKD2_k127_3276233_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 382.0
HKD2_k127_3276233_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 351.0
HKD2_k127_3276233_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000005733 59.0
HKD2_k127_329912_0 PFAM major facilitator superfamily MFS_1 - - - 3.792e-214 677.0
HKD2_k127_329912_1 membrane transporter protein K07090 - - 0.000000000000000000965 86.0
HKD2_k127_3301146_0 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 415.0
HKD2_k127_3301146_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009116 263.0
HKD2_k127_3303253_0 CBS domain containing protein K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 530.0
HKD2_k127_3303253_1 Acetyltransferase (GNAT) family - - - 0.000000000002446 67.0
HKD2_k127_3304582_0 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00335,K05587 - 1.6.5.3 4.8e-218 683.0
HKD2_k127_3304582_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K14091 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 437.0
HKD2_k127_3304582_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 377.0
HKD2_k127_3304582_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000002207 164.0
HKD2_k127_3336558_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 370.0
HKD2_k127_3342415_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 387.0
HKD2_k127_3342415_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005193 259.0
HKD2_k127_33568_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 599.0
HKD2_k127_33568_1 PFAM FAD dependent oxidoreductase K00301 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 420.0
HKD2_k127_3368926_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 531.0
HKD2_k127_3368926_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000004969 134.0
HKD2_k127_3374588_0 Belongs to the ParA family K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 494.0
HKD2_k127_3374588_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 322.0
HKD2_k127_3374588_2 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 296.0
HKD2_k127_3374588_3 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000000000000000000000000003887 146.0
HKD2_k127_3382328_0 Heat shock 70 kDa protein K04043 - - 0.0 1108.0
HKD2_k127_3382328_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 1.261e-269 833.0
HKD2_k127_3382328_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 525.0
HKD2_k127_3382328_3 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 499.0
HKD2_k127_3382328_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 426.0
HKD2_k127_3382328_5 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 366.0
HKD2_k127_3389349_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 1.08e-208 656.0
HKD2_k127_3389349_1 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000001464 151.0
HKD2_k127_3441743_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 452.0
HKD2_k127_3441743_1 DDE superfamily endonuclease - - - 0.0000000000000000000000002714 105.0
HKD2_k127_3441743_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000003503 66.0
HKD2_k127_3465128_0 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 560.0
HKD2_k127_3465128_1 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001138 279.0
HKD2_k127_3465128_2 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003201 288.0
HKD2_k127_3465128_3 - - - - 0.00001369 49.0
HKD2_k127_3472162_0 deoxyhypusine monooxygenase activity K01387 - 3.4.24.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 466.0
HKD2_k127_3472162_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008163 241.0
HKD2_k127_3477779_0 PFAM dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 595.0
HKD2_k127_3477779_1 PFAM Transketolase central region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 578.0
HKD2_k127_3477779_2 Catalytic domain of components of various dehydrogenase complexes K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 305.0
HKD2_k127_3485125_0 ATPase AAA-2 domain protein - - - 4.997e-206 655.0
HKD2_k127_3486303_0 PFAM Cytochrome oxidase assembly K02257,K02259 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 344.0
HKD2_k127_3486303_1 DDE superfamily endonuclease K07494,K07499 - - 0.00007865 48.0
HKD2_k127_3490725_0 PFAM TPR repeat-containing protein - - - 4.164e-231 745.0
HKD2_k127_34973_0 PFAM Methicillin resistance protein - - - 8.153e-203 635.0
HKD2_k127_34973_1 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 319.0
HKD2_k127_3501084_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 422.0
HKD2_k127_3501084_1 PFAM oxidoreductase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000006093 205.0
HKD2_k127_3505681_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00457 - 1.13.11.27 7.997e-196 614.0
HKD2_k127_3505681_1 PFAM fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 451.0
HKD2_k127_3505681_2 PFAM homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002323 268.0
HKD2_k127_3524371_0 conserved protein (COG2071) K09166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002891 273.0
HKD2_k127_3531494_0 TIGRFAM tRNA-guanine transglycosylase, various specificities K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 477.0
HKD2_k127_3531494_1 Ribosomal RNA methyltransferase (FmrO) K18845 - 2.1.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007197 274.0
HKD2_k127_3531494_2 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000006991 209.0
HKD2_k127_3539164_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 487.0
HKD2_k127_3539164_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 331.0
HKD2_k127_3563471_0 methyltransferase K04786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 389.0
HKD2_k127_3581042_0 PFAM oxidoreductase, molybdopterin binding - - - 1.905e-197 629.0
HKD2_k127_3581042_1 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 373.0
HKD2_k127_3581042_2 PFAM Translin K07477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001658 278.0
HKD2_k127_3581042_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000007927 243.0
HKD2_k127_3581042_5 Translation initiation factor SUI1 K03113 - - 0.00000000000000000000000000000000000000000000001284 174.0
HKD2_k127_3581042_8 nitrite reductase [NAD(P)H] activity - - - 0.000000000002844 67.0
HKD2_k127_3581042_9 nitrite reductase [NAD(P)H] activity - - - 0.000601 43.0
HKD2_k127_3582645_0 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 598.0
HKD2_k127_3582645_1 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000001749 176.0
HKD2_k127_3612669_0 TIGRFAM cysteine desulfurase family protein - - - 4.386e-195 616.0
HKD2_k127_3612669_1 Membrane - - - 0.000000000000000000000000004124 123.0
HKD2_k127_3660918_0 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 401.0
HKD2_k127_3660918_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003156 229.0
HKD2_k127_3662327_0 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000000000000006803 191.0
HKD2_k127_3662327_1 Cupin domain - - - 0.00000000000000000000000000000000002828 137.0
HKD2_k127_3662327_2 Redoxin K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.00007927 52.0
HKD2_k127_3679091_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 502.0
HKD2_k127_3679154_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 542.0
HKD2_k127_3679154_1 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 504.0
HKD2_k127_3679154_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 354.0
HKD2_k127_3679154_3 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 347.0
HKD2_k127_3679154_4 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003511 273.0
HKD2_k127_3679154_5 Cytidyltransferase-related domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005874 232.0
HKD2_k127_3681627_0 Molybdopterin oxidoreductase K08356 - 1.20.2.1,1.20.9.1 1.42e-281 881.0
HKD2_k127_3681627_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000002337 264.0
HKD2_k127_3700681_0 elongation factor Tu domain 2 protein K06207 - - 0.0 1013.0
HKD2_k127_370076_0 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 412.0
HKD2_k127_370076_1 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 299.0
HKD2_k127_370076_2 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001219 257.0
HKD2_k127_370076_3 response regulator, receiver K03412,K03413,K07814 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000007439 138.0
HKD2_k127_371278_0 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 427.0
HKD2_k127_371278_1 AMP-binding enzyme K00666 - - 0.0000000000000000001254 96.0
HKD2_k127_371278_2 FAD binding domain - - - 0.000000000222 62.0
HKD2_k127_3715417_0 Pyridoxal-phosphate dependent enzyme - - - 1.152e-253 787.0
HKD2_k127_3715417_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000016 170.0
HKD2_k127_3715417_2 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000012 139.0
HKD2_k127_3734614_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 2.012e-292 911.0
HKD2_k127_3734614_1 peptidase C39 bacteriocin processing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 320.0
HKD2_k127_3737040_0 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 379.0
HKD2_k127_3737040_1 Glycosyl transferase, family 2 - - - 0.00000000000000002928 86.0
HKD2_k127_3747403_0 ATPase activity K03546,K12132,K16786,K16787,K19171 - 2.7.11.1 0.0 1247.0
HKD2_k127_3747403_1 3'-5' exonuclease activity K03546,K03547 - - 0.00000000000000000000000000000000000000000000000000001252 192.0
HKD2_k127_3762462_0 PFAM CoA-binding domain protein K01905,K09181,K22224 - 6.2.1.13 2.007e-207 649.0
HKD2_k127_3762462_1 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 385.0
HKD2_k127_3776655_0 SMART serine threonine protein kinase - - - 2.017e-205 655.0
HKD2_k127_3776655_1 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000000000000000001513 196.0
HKD2_k127_3776655_2 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000001288 183.0
HKD2_k127_3776655_3 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000005876 171.0
HKD2_k127_3786266_0 peptidase C39 bacteriocin processing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 363.0
HKD2_k127_3811562_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 305.0
HKD2_k127_3825788_0 COGs COG3387 Glucoamylase and related glycosyl hydrolase - - - 0.0 1043.0
HKD2_k127_3829157_0 Arginosuccinate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005766 246.0
HKD2_k127_3829157_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000005105 228.0
HKD2_k127_3829157_2 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000000000000000000000000001535 117.0
HKD2_k127_3850995_0 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 289.0
HKD2_k127_3850995_1 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000009357 233.0
HKD2_k127_3850995_2 NifU-like N terminal domain K04488 - - 0.000000000000008341 74.0
HKD2_k127_3855460_0 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 449.0
HKD2_k127_3855460_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 374.0
HKD2_k127_3855460_2 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.00000000000000000000000000003027 118.0
HKD2_k127_3857780_0 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 404.0
HKD2_k127_3857780_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001448 265.0
HKD2_k127_3873096_0 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 466.0
HKD2_k127_3875344_0 TIGRFAM drug resistance transporter, Bcr CflA subfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 501.0
HKD2_k127_3875344_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003664 249.0
HKD2_k127_390382_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 601.0
HKD2_k127_390382_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 472.0
HKD2_k127_390382_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000233 155.0
HKD2_k127_390382_4 - - - - 0.000000000000000000000000000000000002508 144.0
HKD2_k127_3906209_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649,K02594 - 2.3.3.13,2.3.3.14 1.539e-202 635.0
HKD2_k127_3906209_1 DDE superfamily endonuclease K07494 - - 0.0000000000001598 71.0
HKD2_k127_3910471_0 glycoside hydrolase 15-related K01178 - 3.2.1.3 3.719e-257 806.0
HKD2_k127_3910471_1 GDP-mannose mannosyl hydrolase activity - - - 0.000000000000006868 78.0
HKD2_k127_3924430_0 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 567.0
HKD2_k127_3924430_1 Protease prsW family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 545.0
HKD2_k127_3931093_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 4.663e-258 803.0
HKD2_k127_3931093_1 PucR C-terminal helix-turn-helix domain K09684 - - 1.809e-220 695.0
HKD2_k127_3931093_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 420.0
HKD2_k127_3931093_3 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 330.0
HKD2_k127_3931093_4 Transposase - - - 0.00006371 46.0
HKD2_k127_3938602_0 Zinc dependent phospholipase C - - - 0.0009137 51.0
HKD2_k127_3939595_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.353e-227 711.0
HKD2_k127_3951295_0 Belongs to the thiolase family K00632 - 2.3.1.16 1.93e-202 636.0
HKD2_k127_3951295_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 600.0
HKD2_k127_398619_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 489.0
HKD2_k127_398619_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 309.0
HKD2_k127_398619_2 mRNA catabolic process K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000008332 226.0
HKD2_k127_398619_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000001442 227.0
HKD2_k127_398619_4 PFAM regulatory protein, MerR K13640 - - 0.00000000000000000000000000000000000000000000000000000004097 201.0
HKD2_k127_398619_5 Peptidase M50 - - - 0.0000000000000000000000000000000296 128.0
HKD2_k127_399271_0 Transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 407.0
HKD2_k127_4007847_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000004798 244.0
HKD2_k127_4007847_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000001881 224.0
HKD2_k127_4009995_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 407.0
HKD2_k127_4009995_1 Putative zincin peptidase - - - 0.0003328 44.0
HKD2_k127_4035551_0 Asparagine synthase K01953 - 6.3.5.4 1.151e-208 666.0
HKD2_k127_4035551_1 COGs COG5635 NTPase (NACHT family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 399.0
HKD2_k127_4035551_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 321.0
HKD2_k127_4035551_4 sptr a7nhu5 - - - 0.0000000003559 61.0
HKD2_k127_4035551_5 transposase activity - - - 0.0000002924 53.0
HKD2_k127_4043107_0 Serine threonine protein kinase K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 369.0
HKD2_k127_4043107_1 oxidoreductase K14605 - 5.5.1.19 0.00000000000000000000000000000000000000000000000000000003882 200.0
HKD2_k127_4044546_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 4.948e-207 648.0
HKD2_k127_4044546_1 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 397.0
HKD2_k127_4044546_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008562 243.0
HKD2_k127_4044546_3 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000002162 174.0
HKD2_k127_4045168_0 Forkhead associated domain - - - 0.0000000004351 71.0
HKD2_k127_4068822_0 Spermine/spermidine synthase domain - - - 2.047e-220 698.0
HKD2_k127_4068822_1 PFAM peptidase M16 domain protein - - - 9.877e-209 656.0
HKD2_k127_4068822_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000014 267.0
HKD2_k127_4068992_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 7.564e-204 639.0
HKD2_k127_4068992_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 559.0
HKD2_k127_4068992_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000005754 159.0
HKD2_k127_4075176_0 protein histidine kinase activity - - - 2.67e-222 710.0
HKD2_k127_4086514_0 PFAM phenylalanine histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 407.0
HKD2_k127_4086514_1 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000001981 229.0
HKD2_k127_4114162_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 6.83e-280 875.0
HKD2_k127_4114162_1 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000001818 241.0
HKD2_k127_4114162_2 nitrite reductase [NAD(P)H] activity K00363,K05710 - 1.7.1.15 0.00000000000000000000000000000001957 130.0
HKD2_k127_4120944_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 286.0
HKD2_k127_4125200_0 histidine kinase A domain protein K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 501.0
HKD2_k127_4134927_0 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 343.0
HKD2_k127_4134927_1 TPR repeat-containing protein - - - 0.00000000000000000000000000000007792 129.0
HKD2_k127_4145383_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 452.0
HKD2_k127_4145383_1 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003268 258.0
HKD2_k127_4145383_2 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.00000000000000000000000000000000000003266 149.0
HKD2_k127_4145383_3 lactoylglutathione lyase activity K05593 - - 0.0000000000000000000000000000000000005923 144.0
HKD2_k127_4151525_0 Bacterial extracellular solute-binding protein K10236 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 323.0
HKD2_k127_4151525_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000003955 58.0
HKD2_k127_416596_0 PFAM Transglycosylase-associated protein - - - 0.000000000000000000000000000003963 123.0
HKD2_k127_416596_1 DnaJ-class molecular chaperone with C-terminal Zn finger domain - - - 0.00000004449 59.0
HKD2_k127_4167724_0 PFAM Transketolase central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 537.0
HKD2_k127_4167724_1 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 518.0
HKD2_k127_4167724_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 407.0
HKD2_k127_4167724_3 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 308.0
HKD2_k127_4167724_4 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000003538 174.0
HKD2_k127_41753_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 1.16e-200 637.0
HKD2_k127_41753_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 564.0
HKD2_k127_41753_2 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000995 194.0
HKD2_k127_4196879_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 561.0
HKD2_k127_4196879_2 PFAM glycosyl transferase group 1 K00713,K03867,K06338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 448.0
HKD2_k127_4196879_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 351.0
HKD2_k127_4196879_4 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000003949 224.0
HKD2_k127_4196879_5 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000003606 181.0
HKD2_k127_4203736_0 PFAM Glycosyl hydrolases family 31 K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 591.0
HKD2_k127_4205039_0 PFAM amino acid permease-associated region K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 502.0
HKD2_k127_4210268_0 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K11618 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 319.0
HKD2_k127_4210268_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000002729 237.0
HKD2_k127_4210268_2 transposition, DNA-mediated K02529,K20971 - - 0.00000000000000000000006548 99.0
HKD2_k127_4247870_0 PFAM sigma-70 region 2 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 339.0
HKD2_k127_426739_0 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 1.85e-201 636.0
HKD2_k127_426739_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 462.0
HKD2_k127_426739_2 Serine threonine protein kinase K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000009244 242.0
HKD2_k127_4272876_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 7.516e-231 729.0
HKD2_k127_4272876_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000002412 116.0
HKD2_k127_4274060_0 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 334.0
HKD2_k127_4274060_1 belongs to the PRA-CH family K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000002337 188.0
HKD2_k127_4274060_2 Luciferase-like monooxygenase - - - 0.000000000000002921 81.0
HKD2_k127_4274060_3 Required for chromosome condensation and partitioning K03529 - - 0.0000000000001643 72.0
HKD2_k127_4275968_0 Nitrite and sulphite reductase 4Fe-4S domain K00392 - 1.8.7.1 6.694e-275 856.0
HKD2_k127_4275968_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K18313 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008410,GO:0015977,GO:0016740,GO:0016782,GO:0043427,GO:0071704 2.8.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 433.0
HKD2_k127_4275968_2 uroporphyrin-III C-methyltransferase activity K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 325.0
HKD2_k127_4275968_3 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001027 256.0
HKD2_k127_4275968_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000001633 203.0
HKD2_k127_4275968_5 translation release factor activity K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000002951 129.0
HKD2_k127_4275968_6 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000001909 124.0
HKD2_k127_4275968_7 - - - - 0.00000051 59.0
HKD2_k127_4287907_0 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 455.0
HKD2_k127_4287907_1 - - - - 0.0000000000000000000000000000000000000000000000000000000008768 208.0
HKD2_k127_4287907_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000332 70.0
HKD2_k127_4300168_0 PFAM AMP-dependent synthetase and ligase - - - 3.153e-253 793.0
HKD2_k127_4319052_0 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 494.0
HKD2_k127_4319052_1 Amidohydrolase family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 457.0
HKD2_k127_4326092_0 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 577.0
HKD2_k127_4330114_0 Histidine kinase-like ATPases - - - 2.049e-315 983.0
HKD2_k127_4330114_1 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 448.0
HKD2_k127_4331070_0 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 328.0
HKD2_k127_4331070_1 3-demethylubiquinone-9 3-O-methyltransferase activity K15257,K18534 - 2.1.1.295 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 301.0
HKD2_k127_4333713_0 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 5.735e-275 860.0
HKD2_k127_4333713_1 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 451.0
HKD2_k127_4333713_2 PFAM Enoyl-CoA hydratase isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000001368 149.0
HKD2_k127_433947_0 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000000000003729 155.0
HKD2_k127_433947_1 - - - - 0.000000000000000000000000000000001682 131.0
HKD2_k127_433947_2 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000004064 122.0
HKD2_k127_4352019_0 response to copper ion K07156,K14166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 512.0
HKD2_k127_4352019_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 496.0
HKD2_k127_4352019_2 PFAM Glycosyl transferase family 2 K14597 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 473.0
HKD2_k127_4352983_0 PFAM isocitrate isopropylmalate dehydrogenase K05824 - 1.1.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 514.0
HKD2_k127_4352983_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 279.0
HKD2_k127_43535_0 Protein of unknown function (DUF3054) - - - 0.00000000000000000000000051 108.0
HKD2_k127_43535_1 Putative adhesin - - - 0.000000000000000000009272 104.0
HKD2_k127_4355691_0 PFAM VWA containing CoxE family protein K07161 - - 1.592e-217 683.0
HKD2_k127_4355691_1 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 361.0
HKD2_k127_4355691_2 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003478 244.0
HKD2_k127_4355691_3 XdhC and CoxI family - - - 0.00000000000000000000000000000000000000000000000000002249 191.0
HKD2_k127_4355691_4 TRANSCRIPTIONal - - - 0.00000000000002116 78.0
HKD2_k127_4375151_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.000000000000000000000000000000000000000000000000008542 188.0
HKD2_k127_4377169_0 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 2.426e-242 753.0
HKD2_k127_4377169_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 335.0
HKD2_k127_4378299_0 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 2.227e-224 699.0
HKD2_k127_4378299_1 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 302.0
HKD2_k127_4378299_3 protein tyrosine kinase activity K08252 - 2.7.10.1 0.000000000000000000000000000000004969 136.0
HKD2_k127_4378299_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000002826 122.0
HKD2_k127_4378299_5 capsule polysaccharide biosynthetic process K16692 - - 0.0004981 44.0
HKD2_k127_4383311_0 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 562.0
HKD2_k127_4383311_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000002762 61.0
HKD2_k127_4383311_2 F420H(2)-dependent quinone reductase - - - 0.00000002256 58.0
HKD2_k127_4383311_3 - - - - 0.000008954 52.0
HKD2_k127_4391766_0 PFAM amine oxidase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 507.0
HKD2_k127_4406964_0 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 506.0
HKD2_k127_4406964_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 443.0
HKD2_k127_4414846_0 PFAM peptidase M1, membrane alanine aminopeptidase - - - 4.471e-287 895.0
HKD2_k127_4435326_0 Short-chain dehydrogenase reductase SDR K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 396.0
HKD2_k127_4435326_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000001329 117.0
HKD2_k127_44522_0 lipid kinase activity K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000007362 247.0
HKD2_k127_44522_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000005852 228.0
HKD2_k127_44522_2 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000003873 55.0
HKD2_k127_4457384_0 Glutamine synthetase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 387.0
HKD2_k127_4457384_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K01115 - 3.1.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 369.0
HKD2_k127_447500_0 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 2.592e-277 857.0
HKD2_k127_447500_1 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00821,K05830,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 3.875e-250 781.0
HKD2_k127_447500_2 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004856 289.0
HKD2_k127_4482059_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 478.0
HKD2_k127_4482059_2 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000005198 73.0
HKD2_k127_448991_0 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000005584 207.0
HKD2_k127_448991_1 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.00000000000000000000000000000000000000000000000000000008189 202.0
HKD2_k127_4490208_0 COGs COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase K02031,K02032,K10824,K15587,K16784,K16786,K16787 - 3.6.3.24 2.129e-265 828.0
HKD2_k127_4490208_1 transmembrane transporter activity K16783,K16785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 373.0
HKD2_k127_4490208_2 MASE1 domain protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 325.0
HKD2_k127_4490208_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000001982 214.0
HKD2_k127_4492212_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 470.0
HKD2_k127_4493054_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 451.0
HKD2_k127_4493054_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000001412 224.0
HKD2_k127_4493054_2 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.0000000000000000000000000000000000000000000000000004628 185.0
HKD2_k127_4505144_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.792e-234 729.0
HKD2_k127_4505144_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 463.0
HKD2_k127_4505144_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 404.0
HKD2_k127_4505144_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 306.0
HKD2_k127_4505144_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004105 280.0
HKD2_k127_4506948_0 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006879 254.0
HKD2_k127_4506948_1 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000002134 218.0
HKD2_k127_4522489_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 539.0
HKD2_k127_4522489_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002543 235.0
HKD2_k127_4526484_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 561.0
HKD2_k127_4526484_1 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.00000000000000000000000000000000000000000000000486 174.0
HKD2_k127_4526484_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000002381 124.0
HKD2_k127_4526484_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000001616 89.0
HKD2_k127_4535717_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1251.0
HKD2_k127_4554875_0 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 3.153e-222 696.0
HKD2_k127_4561898_2 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000004837 112.0
HKD2_k127_4562456_0 Nacht domain - - - 0.0 1540.0
HKD2_k127_4562456_1 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 494.0
HKD2_k127_4570581_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 601.0
HKD2_k127_457687_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.115e-244 765.0
HKD2_k127_457687_1 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000000000000000000000000000000000000000001755 209.0
HKD2_k127_4580177_0 tetratricopeptide repeat - - - 0.0000000004748 72.0
HKD2_k127_4580177_1 Bacterial transcriptional activator domain - - - 0.0001029 55.0
HKD2_k127_4586491_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 362.0
HKD2_k127_4586491_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000001801 152.0
HKD2_k127_4593360_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 1.278e-207 649.0
HKD2_k127_4593360_1 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 555.0
HKD2_k127_4593360_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 443.0
HKD2_k127_4601088_0 PFAM ABC transporter related K16784,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000557 284.0
HKD2_k127_4601088_1 transmembrane transporter activity K16785,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004891 261.0
HKD2_k127_4638604_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 575.0
HKD2_k127_4638604_1 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 332.0
HKD2_k127_4638604_2 PFAM peptidase M22 glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000811 283.0
HKD2_k127_4638604_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000003344 150.0
HKD2_k127_4638604_4 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000004689 107.0
HKD2_k127_4638604_5 type I restriction modification DNA specificity domain - - - 0.00000000005321 68.0
HKD2_k127_4668890_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1058.0
HKD2_k127_4671893_0 Uncharacterised ACR (DUF711) K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 462.0
HKD2_k127_4671979_0 DREV methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 331.0
HKD2_k127_4671979_1 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.00000000000000000000000000000000000000000000000000000000000000007971 225.0
HKD2_k127_4678004_0 PrkA AAA domain protein K07180 - - 0.0 1155.0
HKD2_k127_4678004_1 SpoVR like protein K06415 - - 2.49e-258 803.0
HKD2_k127_4678004_2 Belongs to the UPF0229 family K09786 - - 3.912e-228 709.0
HKD2_k127_4678004_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000001487 169.0
HKD2_k127_4684572_0 virulence factor MVIN family protein K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 541.0
HKD2_k127_4684572_2 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000004012 224.0
HKD2_k127_4684572_3 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000001003 142.0
HKD2_k127_4684572_4 General stress protein K06884 - - 0.00000000000000000000000001365 111.0
HKD2_k127_4686951_0 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 361.0
HKD2_k127_4686951_2 transmembrane transporter activity - - - 0.000001301 51.0
HKD2_k127_4690754_0 histidine kinase A domain protein K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000002358 177.0
HKD2_k127_4694432_0 AAA domain - - - 7.701e-295 921.0
HKD2_k127_4696836_0 PFAM FAD dependent oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 317.0
HKD2_k127_4696836_1 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.000000000000000000000000000000000000000000000001901 178.0
HKD2_k127_4699891_0 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 302.0
HKD2_k127_4706884_0 Non-ribosomal peptide synthetase modules and related - - - 0.0 1151.0
HKD2_k127_4706884_1 - K18320 - - 0.0000000000000000000000000005665 113.0
HKD2_k127_4708030_0 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001018 284.0
HKD2_k127_4708256_0 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 1.162e-296 922.0
HKD2_k127_4708742_0 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 365.0
HKD2_k127_4708742_1 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009701 254.0
HKD2_k127_4713139_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 400.0
HKD2_k127_4713139_1 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 334.0
HKD2_k127_4713139_2 Nucleotidyl transferase K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000002652 241.0
HKD2_k127_474786_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000001665 234.0
HKD2_k127_474786_1 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000000000000000000000000000000002117 154.0
HKD2_k127_4756638_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 530.0
HKD2_k127_4756638_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 395.0
HKD2_k127_4756638_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 313.0
HKD2_k127_4756638_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000008712 188.0
HKD2_k127_4756638_4 exodeoxyribonuclease VII activity K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000000000641 69.0
HKD2_k127_4760246_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 468.0
HKD2_k127_4760246_1 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 422.0
HKD2_k127_4770451_0 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 578.0
HKD2_k127_4770451_1 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.00000000000000004153 81.0
HKD2_k127_4786747_0 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000901 208.0
HKD2_k127_4786747_1 DinB family - - - 0.00000000000000000000000000000000000000000008833 163.0
HKD2_k127_4786747_2 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000001132 148.0
HKD2_k127_4786747_4 Alpha/beta hydrolase family - - - 0.0002263 45.0
HKD2_k127_4789743_0 PFAM glutamine amidotransferase class-I K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 347.0
HKD2_k127_4803693_0 PhoQ Sensor - - - 5.187e-298 938.0
HKD2_k127_4803693_1 Peptidase dimerisation domain protein K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 322.0
HKD2_k127_4803693_2 cytosine transport - - - 0.00000000000745 66.0
HKD2_k127_4804195_0 Arsenical pump membrane protein K03893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 415.0
HKD2_k127_4804195_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 333.0
HKD2_k127_4804195_3 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000004029 224.0
HKD2_k127_4804195_4 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000005234 159.0
HKD2_k127_4826876_0 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 337.0
HKD2_k127_4833075_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1537.0
HKD2_k127_4833075_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 576.0
HKD2_k127_4833075_2 Belongs to the transketolase family K00615 - 2.2.1.1 0.0000002124 53.0
HKD2_k127_4834929_0 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 498.0
HKD2_k127_4834929_1 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 398.0
HKD2_k127_4834929_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 393.0
HKD2_k127_4834929_3 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001259 259.0
HKD2_k127_4834929_4 TIGRFAM transposase, IS605 OrfB family K07496 - - 0.00000000000000000000000000000000000000000004104 163.0
HKD2_k127_4834929_5 - K18320 - - 0.000000000000001908 78.0
HKD2_k127_4835113_0 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 565.0
HKD2_k127_4835113_1 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 489.0
HKD2_k127_4842462_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 9.465e-211 672.0
HKD2_k127_4842462_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 578.0
HKD2_k127_4842462_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 311.0
HKD2_k127_4847015_0 COGs COG4591 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0 1147.0
HKD2_k127_4847015_1 COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001379 256.0
HKD2_k127_4847015_2 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002874 240.0
HKD2_k127_4847039_0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002453 287.0
HKD2_k127_4847039_1 PFAM beta-lactamase domain protein - - - 0.000000000000000003588 85.0
HKD2_k127_4847039_2 Belongs to the MraZ family K03925 - - 0.00000003625 54.0
HKD2_k127_4852078_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 525.0
HKD2_k127_4852078_1 'glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 352.0
HKD2_k127_485304_0 PFAM Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 281.0
HKD2_k127_485304_1 Mazg nucleotide pyrophosphohydrolase - - - 0.00000000000000000000000000000000000000000000002406 174.0
HKD2_k127_485304_2 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.00000000000002838 72.0
HKD2_k127_4858679_0 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 450.0
HKD2_k127_4858679_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 298.0
HKD2_k127_4858679_2 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002137 279.0
HKD2_k127_4858679_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000005987 138.0
HKD2_k127_4903901_0 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 372.0
HKD2_k127_4903901_1 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009585 357.0
HKD2_k127_4916860_0 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 385.0
HKD2_k127_4917857_0 cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 531.0
HKD2_k127_4917857_1 Baseplate J-like protein K01218 - 3.2.1.78 0.00000000000000000000000000000000000000000000549 181.0
HKD2_k127_4925986_0 Domain of unknown function (DUF1727) - - - 2.557e-242 755.0
HKD2_k127_4925986_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 366.0
HKD2_k127_4925986_2 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000003795 212.0
HKD2_k127_4935609_0 Belongs to the class-I aminoacyl-tRNA synthetase family - - - 9.692e-224 704.0
HKD2_k127_4935609_1 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000005701 93.0
HKD2_k127_4945443_0 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 401.0
HKD2_k127_4949256_0 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 5.785e-224 701.0
HKD2_k127_4949329_0 PFAM Transposase IS66 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 540.0
HKD2_k127_4949329_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 401.0
HKD2_k127_4949329_2 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K00595,K03399 - 2.1.1.132,2.1.1.289 0.0000000000000000000000000000000000000016 156.0
HKD2_k127_4949329_3 Short repeat of unknown function (DUF308) - - - 0.0000000001926 69.0
HKD2_k127_495788_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1040.0
HKD2_k127_495788_1 Domain of unknown function (DUF4397) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002828 274.0
HKD2_k127_495788_2 Protein of unknown function (DUF2795) - - - 0.000000000000000007103 85.0
HKD2_k127_495788_3 - - - - 0.000000000000000832 80.0
HKD2_k127_4965729_0 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001189 232.0
HKD2_k127_4965729_1 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.0000000000000000000000000000000000000000000000000000000009413 213.0
HKD2_k127_4967415_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 361.0
HKD2_k127_4967415_1 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000002002 226.0
HKD2_k127_4967415_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000002364 70.0
HKD2_k127_4973545_0 Gaf domain K02660,K03406,K11525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 510.0
HKD2_k127_4984505_0 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 590.0
HKD2_k127_4984505_1 phosphosulfolactate synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 338.0
HKD2_k127_4988315_0 PFAM single-stranded nucleic acid binding R3H domain protein - - - 1.306e-273 855.0
HKD2_k127_4988315_1 TIGRFAM FeS assembly protein SufD K09015 - - 1.561e-224 704.0
HKD2_k127_4988315_10 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.000008278 48.0
HKD2_k127_4988315_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 4.195e-218 682.0
HKD2_k127_4988315_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 548.0
HKD2_k127_4988315_4 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 535.0
HKD2_k127_4988315_5 PFAM ABC transporter related K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 458.0
HKD2_k127_4988315_6 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 321.0
HKD2_k127_4988315_7 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009377 264.0
HKD2_k127_4988315_8 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000000000000000002989 219.0
HKD2_k127_4988315_9 PFAM MULE transposase, conserved domain - - - 0.0000002252 56.0
HKD2_k127_5013948_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 540.0
HKD2_k127_5013948_1 PFAM molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 317.0
HKD2_k127_5017344_0 Amidohydrolase family K01464,K01466 - 3.5.2.2,3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 359.0
HKD2_k127_5017344_1 OHCU decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000001526 226.0
HKD2_k127_5017344_2 hydroxyisourate hydrolase activity K07127,K13485 GO:0003674,GO:0005488,GO:0005515,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.2.17,4.1.1.97 0.0000000000000000000000000000000000000000004276 160.0
HKD2_k127_502994_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K11473 - - 2.747e-239 749.0
HKD2_k127_502994_1 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 447.0
HKD2_k127_502994_2 Transposase, IS605 OrfB family K07496 - - 0.000000000000000000000009071 101.0
HKD2_k127_5047271_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 438.0
HKD2_k127_5047271_2 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000000005481 161.0
HKD2_k127_5067286_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000002382 186.0
HKD2_k127_5067286_1 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000001536 172.0
HKD2_k127_5073033_0 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 473.0
HKD2_k127_5073033_1 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000002016 177.0
HKD2_k127_5073033_2 - K07498 - - 0.000000000000000000003342 93.0
HKD2_k127_5073033_3 - K07498 - - 0.0003116 44.0
HKD2_k127_5077867_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 1.532e-226 727.0
HKD2_k127_5077867_1 PFAM regulatory protein, ArsR K03892 - - 0.000000000000000000000000000000000000000000000000000000000002639 213.0
HKD2_k127_5077867_2 PFAM blue (type 1) copper domain protein K00368,K02638 - 1.7.2.1 0.0000000000000000000000001064 111.0
HKD2_k127_5103006_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002949 265.0
HKD2_k127_5103006_1 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000561 139.0
HKD2_k127_5104957_0 PFAM AMP-dependent synthetase and ligase K01907 - 6.2.1.16 0.0 1026.0
HKD2_k127_5104957_1 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 507.0
HKD2_k127_5104957_2 S-layer homology domain - - - 0.0000000000000000000000000000000000000000003774 164.0
HKD2_k127_5104957_3 Protein of unknown function (DUF983) - - - 0.00000000000000000000000000000000004244 137.0
HKD2_k127_5104957_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000005194 60.0
HKD2_k127_5104957_5 ABC transporter K01990,K21397 - - 0.00000007123 61.0
HKD2_k127_5106094_0 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 305.0
HKD2_k127_5106094_1 belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005847 244.0
HKD2_k127_5106094_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000007793 216.0
HKD2_k127_5106094_3 - - - - 0.0000000000000000005488 96.0
HKD2_k127_5120761_0 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 500.0
HKD2_k127_5120761_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000001702 235.0
HKD2_k127_5135888_0 Domain of unknown function (DUF1727) - - - 1.336e-202 645.0
HKD2_k127_5135888_1 PFAM CobB CobQ domain protein glutamine amidotransferase K07009 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 451.0
HKD2_k127_5135888_2 unfolded protein binding K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 289.0
HKD2_k127_5136726_0 elongation factor Tu domain 2 protein K02355 - - 0.0 1047.0
HKD2_k127_5136726_1 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 422.0
HKD2_k127_5136726_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 312.0
HKD2_k127_5136726_4 - - - - 0.000001536 51.0
HKD2_k127_5154569_0 Deoxyhypusine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 397.0
HKD2_k127_5154569_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000383 147.0
HKD2_k127_5154569_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000004192 75.0
HKD2_k127_5202069_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 301.0
HKD2_k127_5202069_1 Alpha amylase, catalytic domain - - - 0.000000000000000000000001163 108.0
HKD2_k127_5202069_2 - K18320 - - 0.00000000000000000001704 96.0
HKD2_k127_5209268_0 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 322.0
HKD2_k127_5209268_1 - - - - 0.0000001646 54.0
HKD2_k127_5213646_0 transcription factor binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 429.0
HKD2_k127_5213646_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 409.0
HKD2_k127_5218822_0 - - - - 0.0000000000000000000000000000000000000000000000000000692 189.0
HKD2_k127_5218822_1 Transposase K07494 - - 0.0000000000000000000000000001672 116.0
HKD2_k127_5218822_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000006376 115.0
HKD2_k127_5234533_0 PFAM ABC transporter related K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 517.0
HKD2_k127_5234533_1 PFAM binding-protein-dependent transport systems inner membrane component K05846 - - 0.000000000000000000000000000000000000000000000005431 175.0
HKD2_k127_5235620_0 calcium, potassium:sodium antiporter activity K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 343.0
HKD2_k127_5263897_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.292e-296 917.0
HKD2_k127_5263897_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism - - - 1.406e-199 625.0
HKD2_k127_5277885_0 Flavodoxin K14338 - 1.14.14.1,1.6.2.4 8.019e-220 702.0
HKD2_k127_5277885_1 Oxidoreductase NAD-binding domain K00380,K02641,K14338 - 1.14.14.1,1.18.1.2,1.6.2.4,1.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 417.0
HKD2_k127_5277885_2 PFAM dehydrogenase, E1 component - - - 0.000000000000000000000000000000000000000000000000000000000000000005118 229.0
HKD2_k127_5284193_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 3.294e-221 692.0
HKD2_k127_5286955_0 PFAM Enoyl-CoA hydratase isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 332.0
HKD2_k127_5286955_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000009386 207.0
HKD2_k127_5286955_2 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.0000000000000000000000001439 106.0
HKD2_k127_5295728_0 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.0 1267.0
HKD2_k127_5295728_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.039e-233 726.0
HKD2_k127_5295728_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 287.0
HKD2_k127_5306686_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000001518 241.0
HKD2_k127_5306686_1 methyltransferase activity - - - 0.00003999 49.0
HKD2_k127_5308213_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 497.0
HKD2_k127_5308213_1 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 503.0
HKD2_k127_5308503_0 PFAM acyltransferase 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 356.0
HKD2_k127_5308503_1 cytochrome c oxidase K02351,K02862 - - 0.00000000000007322 73.0
HKD2_k127_5331976_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 454.0
HKD2_k127_5331976_1 Flavin containing amine oxidoreductase K06955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 421.0
HKD2_k127_5331976_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 417.0
HKD2_k127_5331976_3 Eco57I restriction-modification methylase K07317 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 366.0
HKD2_k127_5334038_0 PFAM Glycoside hydrolase family 42 domain protein K12308 - 3.2.1.23 3.583e-291 901.0
HKD2_k127_5334648_1 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 292.0
HKD2_k127_5339265_0 carbohydrate transport K10544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 509.0
HKD2_k127_5339265_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000003771 237.0
HKD2_k127_5339265_2 glycoside hydrolase 15-related K01178 - 3.2.1.3 0.00000000005195 67.0
HKD2_k127_5381228_0 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 600.0
HKD2_k127_5384251_0 SPTR Q471D1 TPR repeat Bacterial transcriptional activator domain Tetratricopeptide TPR_4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004739 264.0
HKD2_k127_5384251_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000001259 141.0
HKD2_k127_5384251_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000003634 68.0
HKD2_k127_5388369_0 HTH-like domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 379.0
HKD2_k127_5388369_1 YD repeat (two copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 338.0
HKD2_k127_5388369_2 transposase activity K07483,K07497 - - 0.000000000000000000000175 100.0
HKD2_k127_5399599_0 ABC transporter K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 406.0
HKD2_k127_5399599_1 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 377.0
HKD2_k127_5399599_2 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000004465 166.0
HKD2_k127_5402015_0 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 418.0
HKD2_k127_5402015_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 348.0
HKD2_k127_5402015_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism - - - 0.00000000000000000000000000000000000002711 147.0
HKD2_k127_5410405_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 450.0
HKD2_k127_5410405_1 SMART ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 427.0
HKD2_k127_5410405_2 protein histidine kinase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 339.0
HKD2_k127_5410405_3 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000126 255.0
HKD2_k127_5415727_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 303.0
HKD2_k127_5415727_1 acyl-coa hydrolase K18014 - 4.3.1.14 0.0000000000000000000000000000000000000000000000000000002704 196.0
HKD2_k127_5415727_2 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000008739 133.0
HKD2_k127_5425281_0 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 458.0
HKD2_k127_5425281_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.00000000000000000000000000000001003 127.0
HKD2_k127_5437623_0 pseudouridine synthase activity K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 323.0
HKD2_k127_5437623_2 Transglycosylase associated protein - - - 0.0000000000000000000000000000000003189 133.0
HKD2_k127_5437623_3 PFAM amino acid permease-associated region K03294 - - 0.0000000000000000007337 87.0
HKD2_k127_5442909_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP - - - 2.444e-243 756.0
HKD2_k127_5442909_1 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 323.0
HKD2_k127_5442909_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 306.0
HKD2_k127_5443615_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.079e-284 883.0
HKD2_k127_5443615_2 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000917 243.0
HKD2_k127_5443615_3 Carbohydrate kinase - - - 0.0000000000000000000000000000008202 121.0
HKD2_k127_5456169_1 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 298.0
HKD2_k127_5456664_0 Psort location CytoplasmicMembrane, score - - - 7.577e-293 910.0
HKD2_k127_5456664_1 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 409.0
HKD2_k127_5456664_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 331.0
HKD2_k127_5456664_3 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000000000000001063 171.0
HKD2_k127_5460527_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 4.641e-202 637.0
HKD2_k127_5460997_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 578.0
HKD2_k127_5460997_1 integral membrane protein - - - 0.0000000000415 64.0
HKD2_k127_5463348_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 1.194e-216 675.0
HKD2_k127_5463348_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 411.0
HKD2_k127_5463348_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 385.0
HKD2_k127_5463348_3 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002017 239.0
HKD2_k127_5465875_0 AMP-binding enzyme C-terminal domain K00666 - - 3.387e-272 846.0
HKD2_k127_5470067_0 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 503.0
HKD2_k127_5470067_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006082,GO:0006725,GO:0006805,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0017076,GO:0019439,GO:0019748,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0047475,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0097367,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 333.0
HKD2_k127_5470067_2 Mo-molybdopterin cofactor biosynthetic process - - - 0.000000000000000000000000000000000000000005907 164.0
HKD2_k127_5470917_0 Belongs to the aldehyde dehydrogenase family - - - 1.758e-197 622.0
HKD2_k127_5484666_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 361.0
HKD2_k127_5484666_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000005373 193.0
HKD2_k127_5484894_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 419.0
HKD2_k127_5484894_1 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 324.0
HKD2_k127_5484894_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 280.0
HKD2_k127_5484894_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001198 284.0
HKD2_k127_5484894_4 DDE superfamily endonuclease - - - 0.0000000214 55.0
HKD2_k127_5488409_0 DDE superfamily endonuclease - - - 0.000000000002548 66.0
HKD2_k127_5488409_1 integral membrane protein - - - 0.0001465 50.0
HKD2_k127_5502613_0 HPP family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 286.0
HKD2_k127_5502613_1 CAAX protease self-immunity K07052 - - 0.00000000003531 73.0
HKD2_k127_5512390_0 nodulation - - - 0.0000000000000000000000000000000000000000000000000000001837 209.0
HKD2_k127_5512390_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000008302 183.0
HKD2_k127_5512390_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000002341 164.0
HKD2_k127_5512390_3 Cupin domain - - - 0.0000000000000000002814 88.0
HKD2_k127_5519958_0 peptidase C60 sortase A and B - - - 0.00000000000000000000000000000000000000000000000000007587 190.0
HKD2_k127_5543998_0 Acetyl-CoA carboxylase, central region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 419.0
HKD2_k127_5543998_1 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 289.0
HKD2_k127_5543998_2 - K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000008374 227.0
HKD2_k127_5543998_3 conserved protein (DUF2249) - - - 0.000000000000000000000000007313 112.0
HKD2_k127_5546744_1 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000001229 143.0
HKD2_k127_5551300_0 Major facilitator Superfamily - - - 7.113e-255 793.0
HKD2_k127_5551300_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 1.462e-221 692.0
HKD2_k127_5562455_0 spore germination K03605 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 347.0
HKD2_k127_5562455_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 302.0
HKD2_k127_5562455_2 - - - - 0.00000000000000000000000000000000000000000000000004144 181.0
HKD2_k127_5562455_3 spore germination K03605 - - 0.000000000000000000000000000000000000000003891 156.0
HKD2_k127_5564396_0 nitrite reductase [NAD(P)H] activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 389.0
HKD2_k127_5564396_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000001354 203.0
HKD2_k127_5570626_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 6.4e-323 994.0
HKD2_k127_5574445_0 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 482.0
HKD2_k127_5574445_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 414.0
HKD2_k127_5574445_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01011,K02439 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000003242 140.0
HKD2_k127_5584365_0 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002471 255.0
HKD2_k127_5584365_1 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000124 151.0
HKD2_k127_5594509_0 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007821 563.0
HKD2_k127_5594509_2 PFAM histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000002796 166.0
HKD2_k127_5603020_0 Alanine-glyoxylate amino-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 446.0
HKD2_k127_5603020_1 CHAP domain K21471 - - 0.00000000000000000000000000000000000000000000000000000000000626 218.0
HKD2_k127_5603020_2 CHAP domain K21471 - - 0.00000000000000000000000000000000000000000000000008187 181.0
HKD2_k127_5627867_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 2.162e-248 772.0
HKD2_k127_5627867_1 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 335.0
HKD2_k127_5633182_0 PFAM peptidase M29, aminopeptidase II K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 559.0
HKD2_k127_5633182_1 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 390.0
HKD2_k127_5633182_2 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000603 270.0
HKD2_k127_5633182_3 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000002542 210.0
HKD2_k127_5633182_4 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000006004 132.0
HKD2_k127_5654924_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 557.0
HKD2_k127_5654924_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008308 347.0
HKD2_k127_5654924_2 Putative exonuclease SbcCD, C subunit - - - 0.00000000000000000000005389 100.0
HKD2_k127_5658847_0 oxidoreductase K14605 - 5.5.1.19 3.557e-199 629.0
HKD2_k127_5658847_1 methyltransferase - - - 0.0000000000000004465 81.0
HKD2_k127_5662751_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 534.0
HKD2_k127_5662751_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 409.0
HKD2_k127_567884_0 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 357.0
HKD2_k127_567884_1 PFAM DNA methylase N-4 N-6 domain protein K00571,K07316 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 289.0
HKD2_k127_5692304_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 531.0
HKD2_k127_5701223_0 PFAM Methicillin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 457.0
HKD2_k127_5701223_1 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 338.0
HKD2_k127_5701223_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 326.0
HKD2_k127_5701223_3 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000415 265.0
HKD2_k127_5701223_4 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000001825 206.0
HKD2_k127_5701223_6 AI-2E family transporter - - - 0.0000001197 55.0
HKD2_k127_5713214_0 high-affinity ferrous iron transmembrane transporter activity K07243 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 331.0
HKD2_k127_5713214_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity - - - 0.000000000000000000000000000000000001025 144.0
HKD2_k127_5713214_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000009675 93.0
HKD2_k127_5720200_0 nodulation K00612 - - 9.156e-225 704.0
HKD2_k127_5720200_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 434.0
HKD2_k127_5720200_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 380.0
HKD2_k127_5738827_0 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 4.795e-224 698.0
HKD2_k127_5738827_1 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000000000000000000000001358 164.0
HKD2_k127_5738827_2 COGs COG1961 Site-specific recombinase DNA invertase Pin homologs K06400 - - 0.0000000000000000000000000002024 116.0
HKD2_k127_5738827_3 DDE superfamily endonuclease - - - 0.000003989 49.0
HKD2_k127_5754562_0 PFAM transposase, IS4 family protein - - - 8.795e-202 632.0
HKD2_k127_5755138_0 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 389.0
HKD2_k127_5768793_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 396.0
HKD2_k127_5768793_1 PFAM glycoside hydrolase family 5 K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000009293 249.0
HKD2_k127_5789791_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 358.0
HKD2_k127_5790095_0 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 517.0
HKD2_k127_5805890_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 407.0
HKD2_k127_5805890_1 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 382.0
HKD2_k127_5805890_2 PFAM Dimethylmenaquinone methyltransferase K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000251 261.0
HKD2_k127_5811076_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.502e-312 964.0
HKD2_k127_5811076_1 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 632.0
HKD2_k127_581190_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 389.0
HKD2_k127_581190_1 Serine aminopeptidase, S33 K22250 - 3.1.1.76 0.00000000000000000000000000000000000000000000000000000000000001609 220.0
HKD2_k127_5813258_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008573 519.0
HKD2_k127_5813258_1 Glycosyltransferase like family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 405.0
HKD2_k127_5813258_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 336.0
HKD2_k127_5813258_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 295.0
HKD2_k127_5828368_0 Metal-independent alpha-mannosidase (GH125) K09704 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 537.0
HKD2_k127_5828368_1 Transposase K07481 - - 0.0000000000000000000000000000000000002909 145.0
HKD2_k127_5828368_2 Glycosyl hydrolase K09704 - - 0.000000000000000001035 88.0
HKD2_k127_5836543_0 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 554.0
HKD2_k127_5836543_1 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 396.0
HKD2_k127_5836543_2 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 364.0
HKD2_k127_5836543_3 protein some members contain a von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000001095 229.0
HKD2_k127_5836543_4 LysM domain - - - 0.0000000000000000000000001593 122.0
HKD2_k127_5840675_0 Pfam:Methyltransf_26 - - - 4.174e-267 847.0
HKD2_k127_5840675_1 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000005826 102.0
HKD2_k127_5845377_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1763.0
HKD2_k127_5851514_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 406.0
HKD2_k127_5851514_1 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000006556 203.0
HKD2_k127_5851514_2 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000212 106.0
HKD2_k127_5851644_0 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 570.0
HKD2_k127_5851644_1 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 572.0
HKD2_k127_5855503_0 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000481 211.0
HKD2_k127_5855503_1 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000000000002884 149.0
HKD2_k127_5864095_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 6.691e-222 696.0
HKD2_k127_5864095_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 2.052e-221 697.0
HKD2_k127_5864095_2 all-trans-retinol 13,14-reductase activity - - - 5.567e-213 670.0
HKD2_k127_5864095_5 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000001713 67.0
HKD2_k127_5864095_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.0005014 53.0
HKD2_k127_5879715_0 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000000002836 241.0
HKD2_k127_5903543_0 ATPase AAA-2 domain protein K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 2.558e-218 683.0
HKD2_k127_5911744_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 8.269e-290 908.0
HKD2_k127_5923167_0 Glycogen debranching enzyme N terminal - - - 8.777e-227 711.0
HKD2_k127_5923167_1 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000001774 185.0
HKD2_k127_5929763_0 PFAM binding-protein-dependent transport systems inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 287.0
HKD2_k127_5929763_1 PFAM Substrate-binding region of ABC-type glycine betaine transport system K05845 - - 0.00000000000000000000000000000000000000000000000000000000005743 210.0
HKD2_k127_5929763_2 PFAM binding-protein-dependent transport systems inner membrane component K05846 - - 0.00000000000000000000000000000000000000000002679 163.0
HKD2_k127_5934042_0 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 366.0
HKD2_k127_5934042_1 Belongs to the HpcH HpaI aldolase family K01644,K08691 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 346.0
HKD2_k127_5934042_2 - - - - 0.0000000000000000000000000000000000000000000000000001681 185.0
HKD2_k127_5934254_0 Tex-like protein N-terminal domain K06959 - - 0.0 1123.0
HKD2_k127_5934254_1 protein kinase activity - - - 0.0000000000000000000000000001502 120.0
HKD2_k127_5934724_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 507.0
HKD2_k127_5934724_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002388 280.0
HKD2_k127_5945114_0 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 293.0
HKD2_k127_5945114_2 Isochorismatase family - - - 0.0000000000000000000000002911 106.0
HKD2_k127_5961667_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 556.0
HKD2_k127_5961667_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 537.0
HKD2_k127_5961667_2 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 359.0
HKD2_k127_5961667_3 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003599 248.0
HKD2_k127_597792_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 5.224e-224 705.0
HKD2_k127_597792_1 anaphase-promoting complex binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001083 288.0
HKD2_k127_597792_2 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000005101 214.0
HKD2_k127_5980341_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 289.0
HKD2_k127_5980341_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004085 275.0
HKD2_k127_5986809_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1e-323 997.0
HKD2_k127_5986809_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 9.287e-207 647.0
HKD2_k127_5986809_2 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 285.0
HKD2_k127_5986809_3 Dihydrouridine synthase (Dus) - - - 0.000000000000000000000000000000000000000000000000000000000000000001295 235.0
HKD2_k127_5993797_0 PFAM ABC transporter related K10112 - - 0.000000000000000000000000000000000000000000000000000000000004532 211.0
HKD2_k127_5993797_1 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000003002 207.0
HKD2_k127_5994462_0 peptidyl-tyrosine sulfation - - - 7.646e-239 745.0
HKD2_k127_5994462_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.408e-202 641.0
HKD2_k127_6031254_0 Transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 463.0
HKD2_k127_6031254_1 zinc ion binding K04486 - 3.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 311.0
HKD2_k127_6031254_2 PFAM O-methyltransferase, family 3 K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 289.0
HKD2_k127_6031254_3 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000699 71.0
HKD2_k127_6050178_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 427.0
HKD2_k127_6050178_1 SMART serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 311.0
HKD2_k127_6050178_2 Translation initiation factor SUI1 K03113 - - 0.00000000000000000000000000000000000000004682 154.0
HKD2_k127_6065091_0 Type III restriction protein res subunit - - - 5.391e-222 696.0
HKD2_k127_6065091_1 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 490.0
HKD2_k127_6065091_2 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001836 255.0
HKD2_k127_6065091_3 site-specific DNA-methyltransferase (adenine-specific) activity K03427 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000006603 238.0
HKD2_k127_6070483_0 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 416.0
HKD2_k127_6070483_1 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 377.0
HKD2_k127_6070483_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000001709 107.0
HKD2_k127_6074210_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 510.0
HKD2_k127_6074210_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 499.0
HKD2_k127_6074210_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 409.0
HKD2_k127_6074210_3 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000000001308 260.0
HKD2_k127_6074210_4 - - - - 0.00000000000000000000000000000000000000148 148.0
HKD2_k127_6074210_5 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000000000001133 139.0
HKD2_k127_6088056_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 426.0
HKD2_k127_6088056_1 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000001368 232.0
HKD2_k127_6088056_2 periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000001205 175.0
HKD2_k127_6088056_3 Transposase - - - 0.000000000000000000000000000000000000000000000004119 175.0
HKD2_k127_6088850_0 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 596.0
HKD2_k127_6088850_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000006909 137.0
HKD2_k127_6088850_2 all-trans-retinol 13,14-reductase activity - - - 0.0000001163 55.0
HKD2_k127_6089090_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000001162 209.0
HKD2_k127_6089090_2 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000000000000000000000001003 203.0
HKD2_k127_6108359_0 DNA Topoisomerase IV - - - 0.0 1184.0
HKD2_k127_6108359_1 TopoisomeraseII - - - 0.0 1167.0
HKD2_k127_6108359_2 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 417.0
HKD2_k127_6108359_3 protein transport - - - 0.0000000000000000000000000007302 116.0
HKD2_k127_6108359_4 DinB superfamily - - - 0.000000000000000000000003336 108.0
HKD2_k127_6120929_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001599 291.0
HKD2_k127_6120929_1 Alkyl hydroperoxide reductase and or thiol-specific antioxidant family (AhpC TSA) protein - - - 0.00000000000000000000000000000000000000000000000005768 178.0
HKD2_k127_6128190_0 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000001738 192.0
HKD2_k127_6128190_1 quinone binding - - - 0.0000000000000000000000000000000000000000000001569 172.0
HKD2_k127_6128190_2 Transport permease protein K01992 - - 0.0000000000000000001538 89.0
HKD2_k127_6132272_0 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000003749 233.0
HKD2_k127_6132272_2 PFAM short chain dehydrogenase - - - 0.0000000000000000000000000000000000003245 143.0
HKD2_k127_6145397_0 TIGRFAM transposase, IS605 OrfB family K07496 - - 0.00000000000000000000000000000000000000000000000001157 181.0
HKD2_k127_6145397_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000004841 140.0
HKD2_k127_6145397_2 Monogalactosyldiacylglycerol (MGDG) synthase K03429,K03715 - 2.4.1.315,2.4.1.46 0.000000000000000000000000002241 125.0
HKD2_k127_6151111_0 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 451.0
HKD2_k127_6151111_1 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 408.0
HKD2_k127_6151111_2 FtsZ-dependent cytokinesis K03975,K19302 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0050896,GO:0051301,GO:0071944 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000007712 245.0
HKD2_k127_6151111_3 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000009777 224.0
HKD2_k127_6161520_0 PFAM coenzyme PQQ synthesis - - - 0.00000000000000000000000000000004576 129.0
HKD2_k127_6169068_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 6.353e-200 627.0
HKD2_k127_6170860_0 nitrite reductase [NAD(P)H] activity K16937 - 1.8.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 368.0
HKD2_k127_6170860_1 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000495 274.0
HKD2_k127_6170860_2 mercury ion transmembrane transporter activity K07213,K08364 - - 0.0000000000000000136 84.0
HKD2_k127_6170860_3 - - - - 0.000002453 53.0
HKD2_k127_6170860_4 PFAM major facilitator superfamily MFS_1 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0001073 46.0
HKD2_k127_6191764_0 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 441.0
HKD2_k127_6191764_1 Belongs to the glycosyl hydrolase 13 family K01200 - 3.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 383.0
HKD2_k127_6193095_0 Carotenoid biosynthesis protein K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000001815 229.0
HKD2_k127_6193095_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000003896 93.0
HKD2_k127_6203632_0 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 3.742e-300 928.0
HKD2_k127_6203632_2 histone H2A K63-linked ubiquitination K21832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 305.0
HKD2_k127_6208392_0 HELICc2 K03722 - 3.6.4.12 0.0 1179.0
HKD2_k127_6229291_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 396.0
HKD2_k127_6229291_1 DNA binding domain - - - 0.000000000000000000000000001267 113.0
HKD2_k127_6239781_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 5.836e-239 753.0
HKD2_k127_6239781_1 Electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000137 225.0
HKD2_k127_6246121_0 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000008918 188.0
HKD2_k127_6246121_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000001113 168.0
HKD2_k127_6246121_3 spore germination - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000002922 100.0
HKD2_k127_6254955_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.319e-303 944.0
HKD2_k127_6254955_1 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 431.0
HKD2_k127_6254955_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 404.0
HKD2_k127_6254955_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 377.0
HKD2_k127_6254955_4 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000000000000000000000001663 203.0
HKD2_k127_6254955_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000002372 182.0
HKD2_k127_6260002_0 proteolysis K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 295.0
HKD2_k127_6260002_1 proteolysis K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000004733 266.0
HKD2_k127_6262552_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 546.0
HKD2_k127_6262552_1 Cys/Met metabolism PLP-dependent enzyme K11325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 474.0
HKD2_k127_6262552_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 397.0
HKD2_k127_6262552_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 395.0
HKD2_k127_6262552_4 PFAM TrkA-N domain protein - - - 0.0000000000000008557 78.0
HKD2_k127_6267556_0 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 293.0
HKD2_k127_6267556_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000003789 147.0
HKD2_k127_6268762_0 ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD K16013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 399.0
HKD2_k127_6269862_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 2.566e-240 755.0
HKD2_k127_6269862_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 517.0
HKD2_k127_6269862_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000004757 179.0
HKD2_k127_6269862_3 TIGRFAM sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.0000000000000000000000000000000000000006793 149.0
HKD2_k127_6269862_4 TIGRFAM sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.00000000000000002673 85.0
HKD2_k127_6275665_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 599.0
HKD2_k127_6277814_0 PFAM Methicillin resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 578.0
HKD2_k127_6277814_1 PFAM Methicillin resistance protein - - - 0.0000000002899 61.0
HKD2_k127_6277814_2 Transposase - - - 0.0000008066 51.0
HKD2_k127_6285144_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 578.0
HKD2_k127_6285144_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 327.0
HKD2_k127_6285144_2 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009887 252.0
HKD2_k127_6300884_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 439.0
HKD2_k127_6300884_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000001024 93.0
HKD2_k127_6307925_0 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000000000001354 170.0
HKD2_k127_6307925_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0000000000000000000000006282 111.0
HKD2_k127_6313236_0 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 323.0
HKD2_k127_6313236_1 - K09932 - - 0.0000000000000000000000000614 109.0
HKD2_k127_631603_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 2.307e-217 681.0
HKD2_k127_631603_1 PFAM Chlorite dismutase - - - 0.000000000000000000000000000006378 119.0
HKD2_k127_6322269_0 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 421.0
HKD2_k127_6322269_1 Pfam:Methyltransf_26 - - - 0.0000000000000000000000000000000000000004456 152.0
HKD2_k127_6324614_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 422.0
HKD2_k127_6324614_1 FES - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 364.0
HKD2_k127_632486_0 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 511.0
HKD2_k127_632486_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 428.0
HKD2_k127_632486_2 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000898 106.0
HKD2_k127_6326030_0 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 353.0
HKD2_k127_6326030_1 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000000000005511 99.0
HKD2_k127_6326030_2 - - - - 0.000000000000000000009119 92.0
HKD2_k127_6326030_3 Biotin-requiring enzyme K02160 - - 0.0000166 49.0
HKD2_k127_6331340_0 Glycogen debranching enzyme - - - 1.804e-214 678.0
HKD2_k127_6331340_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000003739 130.0
HKD2_k127_6331340_2 Glycogen debranching enzyme - - - 0.0000000000000000000000001457 111.0
HKD2_k127_6331340_3 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.00000000000002142 74.0
HKD2_k127_6350851_0 Catalase domain protein K03781 - 1.11.1.6 2.065e-282 872.0
HKD2_k127_6357634_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 311.0
HKD2_k127_6357634_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000002584 179.0
HKD2_k127_6357634_2 response regulator, receiver - - - 0.0000000000000000000000002748 109.0
HKD2_k127_6364541_0 SMART DNA-directed DNA polymerase B - - - 0.00000000000000000000000000000000000000000000000000567 185.0
HKD2_k127_6364541_1 TIGRFAM isochorismate synthase K02361,K02552 - 5.4.4.2 0.000000000000000000000000000000005987 135.0
HKD2_k127_6366621_0 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 415.0
HKD2_k127_6366621_1 MaoC domain protein dehydratase K00634,K17865 - 2.3.1.19,4.2.1.55 0.000000000000000000007853 98.0
HKD2_k127_6367783_0 PFAM ComEC Rec2-related protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 344.0
HKD2_k127_6367783_2 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000003215 69.0
HKD2_k127_6367842_0 Belongs to the SEDS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 543.0
HKD2_k127_6367842_1 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000000000000000000000000000007855 218.0
HKD2_k127_6367842_2 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000001325 211.0
HKD2_k127_6378710_0 ATP-binding region, ATPase domain protein K02487,K03407,K06596 - 2.7.13.3 0.0 1316.0
HKD2_k127_6378710_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 555.0
HKD2_k127_6378710_2 - - - - 0.00000000000000179 76.0
HKD2_k127_6391775_0 Eco57I restriction-modification methylase K07317 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 331.0
HKD2_k127_6391775_1 GDP-mannose mannosyl hydrolase activity K03574,K13669 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000005434 234.0
HKD2_k127_6391775_2 - - - - 0.00000000000000000000000000000000000000000002741 164.0
HKD2_k127_6398378_0 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 523.0
HKD2_k127_6398378_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000006712 93.0
HKD2_k127_6398378_2 Capsular exopolysaccharide family - - - 0.000000000000009196 79.0
HKD2_k127_6406252_0 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 560.0
HKD2_k127_6407766_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 578.0
HKD2_k127_6407766_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000003989 195.0
HKD2_k127_6407766_2 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000007199 157.0
HKD2_k127_6433286_0 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 497.0
HKD2_k127_6433286_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 321.0
HKD2_k127_6433286_2 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000000000022 211.0
HKD2_k127_6433286_5 protein secretion K03116 - - 0.0000000000000000007453 89.0
HKD2_k127_6437106_0 SMART serine threonine protein kinase - - - 3.712e-195 615.0
HKD2_k127_6437106_1 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 341.0
HKD2_k127_6437106_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000001536 209.0
HKD2_k127_6442560_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 504.0
HKD2_k127_6449391_0 Aminoacyl-tRNA editing domain K01284 - 3.4.15.5 0.000000000000000000000000000000000000000000000000000000000003974 211.0
HKD2_k127_6449391_1 sh3 domain protein K07282 - - 0.0000000000000000000000000000000000000000005885 170.0
HKD2_k127_6451887_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 398.0
HKD2_k127_6451887_1 ADP-ribosylation factor family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 377.0
HKD2_k127_6451887_2 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 363.0
HKD2_k127_6454781_0 Endoribonuclease that initiates mRNA decay K18682 - - 3.853e-248 774.0
HKD2_k127_6454781_1 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 395.0
HKD2_k127_6454781_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000002103 233.0
HKD2_k127_6461830_0 PFAM AAA ATPase central domain protein K07478 - - 5.892e-209 658.0
HKD2_k127_6461830_1 chromate transport K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000004865 226.0
HKD2_k127_6461830_2 chromate transport K07240 - - 0.000000000000000000000000000000000000000000000000000000003301 206.0
HKD2_k127_6476039_0 glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 0.0 1276.0
HKD2_k127_6476039_1 Spermine/spermidine synthase domain - - - 1.991e-205 648.0
HKD2_k127_6476039_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 435.0
HKD2_k127_6506301_0 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 362.0
HKD2_k127_6506301_1 Molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 330.0
HKD2_k127_6508846_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 496.0
HKD2_k127_6511393_1 protein homooligomerization - - - 0.000000000000000000000000005049 115.0
HKD2_k127_6511393_2 Gas vesicle synthesis protein GvpL/GvpF - - - 0.00000000000000000000000982 104.0
HKD2_k127_6524004_1 TIGRFAM MazG family protein K02499 - - 0.0000000000000000000000000065 114.0
HKD2_k127_6524004_2 Glycosyltransferase 28 domain K03715 - 2.4.1.46 0.00000000002429 72.0
HKD2_k127_6524004_3 Alpha beta hydrolase K02170 - 3.1.1.85 0.00000000002536 74.0
HKD2_k127_6524564_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.191e-236 736.0
HKD2_k127_6524564_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 541.0
HKD2_k127_654450_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 586.0
HKD2_k127_654450_1 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009581 336.0
HKD2_k127_6547890_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 404.0
HKD2_k127_6547890_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005057 251.0
HKD2_k127_6555630_0 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000001234 201.0
HKD2_k127_6555630_1 organic acid phosphorylation K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000175 168.0
HKD2_k127_6555630_2 AAA domain K07028 - - 0.00000000000000000000000000005805 121.0
HKD2_k127_656678_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 338.0
HKD2_k127_656678_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000001066 143.0
HKD2_k127_656746_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.069e-243 766.0
HKD2_k127_656746_1 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 490.0
HKD2_k127_656746_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000002253 245.0
HKD2_k127_656746_4 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000001608 145.0
HKD2_k127_656746_5 cellular water homeostasis K16052 - - 0.00000000000000000000000000000000001248 139.0
HKD2_k127_656746_6 Bacterial protein of unknown function (DUF951) - - - 0.000000000000000000000000000002245 121.0
HKD2_k127_6572010_0 Serine aminopeptidase, S33 K22250 - 3.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 297.0
HKD2_k127_6572010_1 Bacterial regulatory helix-turn-helix protein, lysR family K21960 - - 0.0000000000000000000000000000000000000000000000000000000000003058 222.0
HKD2_k127_6572010_2 carboxylic ester hydrolase activity K03929 - - 0.00000013 53.0
HKD2_k127_6579141_0 Major facilitator Superfamily K08176,K08368 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 452.0
HKD2_k127_6610393_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 1.389e-220 690.0
HKD2_k127_6613630_0 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000984 245.0
HKD2_k127_6613630_1 amidase activity K01448,K02395,K17733 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000009765 217.0
HKD2_k127_6617668_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 7.181e-224 710.0
HKD2_k127_6625298_0 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 344.0
HKD2_k127_6625298_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003073 275.0
HKD2_k127_6625298_2 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.00000000000000000000000000000000000000008515 152.0
HKD2_k127_6642652_0 SMART serine threonine protein kinase K12132 - 2.7.11.1 1.172e-199 640.0
HKD2_k127_6642652_1 Selenocysteine-specific translation elongation factor K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 474.0
HKD2_k127_6647462_0 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000004941 263.0
HKD2_k127_6647462_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000003049 218.0
HKD2_k127_6661793_0 Glycoside hydrolase family 3 domain protein K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 354.0
HKD2_k127_6665043_0 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009548 416.0
HKD2_k127_6665043_1 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 304.0
HKD2_k127_6675822_0 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 311.0
HKD2_k127_6675822_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000001399 214.0
HKD2_k127_6675822_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000003398 94.0
HKD2_k127_6680936_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K15580 - - 7.561e-221 698.0
HKD2_k127_6680936_2 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K15580 - - 0.00000000000000002697 84.0
HKD2_k127_6693999_0 Alcohol dehydrogenase GroES domain protein K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 376.0
HKD2_k127_6696567_1 Endodeoxyribonuclease RusA K01160 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000009467 224.0
HKD2_k127_6696567_2 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000000000000000000000000000002145 218.0
HKD2_k127_6700375_0 von Willebrand factor (vWF) type A domain - - - 0.0 1125.0
HKD2_k127_6700375_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 1.047e-254 789.0
HKD2_k127_6700375_2 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 360.0
HKD2_k127_6702351_0 peptidase C39 bacteriocin processing - - - 2.023e-249 794.0
HKD2_k127_6702473_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.7e-279 866.0
HKD2_k127_6702473_1 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 370.0
HKD2_k127_6702473_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000008811 162.0
HKD2_k127_6719574_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 582.0
HKD2_k127_6719574_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 555.0
HKD2_k127_6722528_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 464.0
HKD2_k127_6722528_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 411.0
HKD2_k127_6757478_0 Lanthionine synthetase C-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 291.0
HKD2_k127_6757478_1 peptidase C39 bacteriocin processing - - - 0.0000000000000000000000000000000000000000000000000000000004761 210.0
HKD2_k127_6763322_0 Protein of unknown function (DUF2785) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 325.0
HKD2_k127_6763322_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000004249 146.0
HKD2_k127_6763322_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000005888 147.0
HKD2_k127_6771069_0 SPTR Q2LSA8 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 376.0
HKD2_k127_6771069_1 SPTR B0JN73 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003334 256.0
HKD2_k127_6771069_2 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000001832 145.0
HKD2_k127_6771069_3 - - - - 0.000000000000003575 87.0
HKD2_k127_6778292_0 protein histidine kinase activity - - - 2.785e-194 613.0
HKD2_k127_6778292_1 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 383.0
HKD2_k127_6785683_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 572.0
HKD2_k127_6785683_1 PFAM glycosyl transferase family 9 K02843,K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 526.0
HKD2_k127_6785683_2 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 441.0
HKD2_k127_6785683_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 351.0
HKD2_k127_6785683_5 TIGRFAM transposase, IS605 OrfB family K07496 - - 0.0000000000000000000000000000000000005238 145.0
HKD2_k127_6785683_6 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K03574 - 3.6.1.55 0.000000000000000000000000000000000002528 145.0
HKD2_k127_6788419_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1409.0
HKD2_k127_6788419_1 cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 344.0
HKD2_k127_6789306_0 protein histidine kinase activity - - - 7.757e-242 766.0
HKD2_k127_6789306_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 433.0
HKD2_k127_6789306_2 PFAM PspA IM30 family protein K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002216 278.0
HKD2_k127_6792143_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 601.0
HKD2_k127_6792143_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 512.0
HKD2_k127_6792143_2 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 501.0
HKD2_k127_6792143_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 371.0
HKD2_k127_6792143_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 340.0
HKD2_k127_6792143_5 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000009497 210.0
HKD2_k127_6801267_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 491.0
HKD2_k127_6801267_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 402.0
HKD2_k127_6801267_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 302.0
HKD2_k127_6801267_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000001526 142.0
HKD2_k127_6801267_4 ABC-2 family transporter protein - - - 0.00000000000000000003992 98.0
HKD2_k127_6804358_0 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 434.0
HKD2_k127_6804358_1 cysteine-type peptidase activity K21471 - - 0.000000000000000000000000000000000000000000000000000318 189.0
HKD2_k127_6808834_0 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 402.0
HKD2_k127_6808834_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K02078,K13611,K15337 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 293.0
HKD2_k127_6812455_0 type III restriction protein res subunit K10843 - 3.6.4.12 1.605e-287 890.0
HKD2_k127_6812455_1 PFAM mannose-6-phosphate isomerase type I K01809 - 5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 480.0
HKD2_k127_6812455_12 belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000002155 140.0
HKD2_k127_6812455_14 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000001301 51.0
HKD2_k127_6812455_2 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 414.0
HKD2_k127_6812455_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 397.0
HKD2_k127_6812455_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 412.0
HKD2_k127_6812455_5 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 381.0
HKD2_k127_6812455_6 - K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 336.0
HKD2_k127_6812455_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000227 278.0
HKD2_k127_6812455_8 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000003022 263.0
HKD2_k127_6812455_9 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000379 186.0
HKD2_k127_6820413_0 Acts as a magnesium transporter K06213 - - 7.004e-256 804.0
HKD2_k127_6820413_1 anaphase-promoting complex binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 529.0
HKD2_k127_6820413_2 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 372.0
HKD2_k127_6820413_3 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 342.0
HKD2_k127_6820413_4 hydrolase of the alpha beta K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 314.0
HKD2_k127_6825238_0 collagen metabolic process K08677 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 489.0
HKD2_k127_6825238_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 324.0
HKD2_k127_6825238_2 SnoaL-like polyketide cyclase - - - 0.00000000000000001991 81.0
HKD2_k127_6832851_0 Thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 524.0
HKD2_k127_6832851_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 327.0
HKD2_k127_6832851_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000005934 183.0
HKD2_k127_6839946_1 - - - - 0.00000000000000000000000000000000000000001581 156.0
HKD2_k127_6839946_2 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000629 148.0
HKD2_k127_6854384_0 Pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000004142 255.0
HKD2_k127_6860450_0 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 392.0
HKD2_k127_6860450_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 301.0
HKD2_k127_6869588_0 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 491.0
HKD2_k127_6869588_1 Ribonuclease HI K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.00000000000000000000000000000000001749 144.0
HKD2_k127_6883837_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 7.76e-227 707.0
HKD2_k127_6883837_1 TIGRFAM membrane-associated zinc metalloprotease K11749 - - 0.000000000000000000000000000000006616 128.0
HKD2_k127_6893972_0 Fibronectin-binding A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 522.0
HKD2_k127_690167_0 deoxyhypusine monooxygenase activity K01186 - 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 365.0
HKD2_k127_690167_1 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 328.0
HKD2_k127_690167_2 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 304.0
HKD2_k127_6912233_0 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 338.0
HKD2_k127_6912233_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000007732 105.0
HKD2_k127_6914345_0 COGs COG3387 Glucoamylase and related glycosyl hydrolase K07190 - - 1.14e-307 950.0
HKD2_k127_6929653_0 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 309.0
HKD2_k127_6929653_1 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000008073 194.0
HKD2_k127_6929653_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000004853 128.0
HKD2_k127_6940806_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075,K15780 - 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 436.0
HKD2_k127_6940806_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000111 268.0
HKD2_k127_6950894_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 350.0
HKD2_k127_6950894_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000002083 216.0
HKD2_k127_6961343_0 CpXC protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002667 273.0
HKD2_k127_6961343_1 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003355 249.0
HKD2_k127_6961343_2 anaphase-promoting complex binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004003 250.0
HKD2_k127_6991292_0 TIGRFAM acetylornithine and succinylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 6.443e-206 646.0
HKD2_k127_7002240_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 593.0
HKD2_k127_7008263_0 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 1.304e-263 821.0
HKD2_k127_7008263_1 PFAM Haloacid dehalogenase domain protein hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000005111 260.0
HKD2_k127_7024133_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.729e-205 661.0
HKD2_k127_7024284_0 PFAM AAA ATPase central domain protein K06413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 391.0
HKD2_k127_7024284_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000431 272.0
HKD2_k127_7024284_2 SPTR B2JC10 Transposase IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000008227 217.0
HKD2_k127_7025909_0 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 593.0
HKD2_k127_7025909_1 SPTR D1CGX5 Response regulator receiver protein - - - 0.00000000000000000000000000000000000000006517 156.0
HKD2_k127_7025909_2 Osmosensitive K+ channel His kinase sensor domain - - - 0.0000000000000000000000000000006329 124.0
HKD2_k127_7044016_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 551.0
HKD2_k127_7044016_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02484,K07642,K07653,K07654 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 333.0
HKD2_k127_7045460_0 phosphatidylinositol metabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 403.0
HKD2_k127_7045460_1 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002905 265.0
HKD2_k127_7046850_0 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 442.0
HKD2_k127_7046850_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000009414 149.0
HKD2_k127_7057338_0 Dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 474.0
HKD2_k127_7057338_1 ATP-NAD kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 295.0
HKD2_k127_7057338_2 Transketolase, pyrimidine binding domain K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003488 249.0
HKD2_k127_7079024_0 capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000007801 175.0
HKD2_k127_7079024_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000002527 156.0
HKD2_k127_7079024_2 Protein of unknown function (DUF4012) - - - 0.0000000008269 66.0
HKD2_k127_7079680_0 PFAM DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 379.0
HKD2_k127_7079680_1 DNA helicase K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000212 186.0
HKD2_k127_7089556_0 Bacterial PH domain K08981 - - 2.881e-196 625.0
HKD2_k127_7091142_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000005746 220.0
HKD2_k127_7091720_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005729 258.0
HKD2_k127_7091720_1 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008481 239.0
HKD2_k127_7091720_2 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000006981 199.0
HKD2_k127_7101234_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 457.0
HKD2_k127_7101234_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 436.0
HKD2_k127_7117697_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 5.615e-300 933.0
HKD2_k127_7117697_1 PFAM DNA methylase N-4 N-6 domain protein K00571,K07316 - 2.1.1.72 0.000000000000000000000000000000000000000004732 159.0
HKD2_k127_7120011_0 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 529.0
HKD2_k127_7120011_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 304.0
HKD2_k127_7120011_2 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000004655 267.0
HKD2_k127_7121393_0 PFAM phospholipase D Transphosphatidylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 521.0
HKD2_k127_7121393_1 recombinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002593 282.0
HKD2_k127_7121393_2 plasmid maintenance K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000002834 147.0
HKD2_k127_7121393_3 Resolvase, N terminal domain - - - 0.00004342 47.0
HKD2_k127_7133466_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.963e-311 962.0
HKD2_k127_7133466_1 Transposase DDE domain - - - 0.0000000000132 70.0
HKD2_k127_7135879_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 1.654e-256 806.0
HKD2_k127_7135879_1 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 398.0
HKD2_k127_7135879_2 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 400.0
HKD2_k127_7135879_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 303.0
HKD2_k127_7136897_0 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 470.0
HKD2_k127_7136897_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 338.0
HKD2_k127_7147378_0 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 580.0
HKD2_k127_7147378_1 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000002754 133.0
HKD2_k127_7147378_2 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.0000000000000000000124 98.0
HKD2_k127_7149622_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 326.0
HKD2_k127_7150004_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 3.634e-290 913.0
HKD2_k127_7150004_1 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000003794 229.0
HKD2_k127_7153924_0 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 496.0
HKD2_k127_7153924_1 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 462.0
HKD2_k127_7153924_2 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 328.0
HKD2_k127_7153924_3 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 319.0
HKD2_k127_7153924_4 DoxX - - - 0.0000000000000000000000000000000000000000000009739 169.0
HKD2_k127_7153924_5 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000004586 127.0
HKD2_k127_7167197_0 Protein of unknown function (DUF790) K09744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 609.0
HKD2_k127_7167197_1 oxalate decarboxylase activity K01569 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0033609,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046564,GO:0071704 4.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 453.0
HKD2_k127_7167197_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 355.0
HKD2_k127_7167197_3 Oxalate decarboxylase K01569 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0033609,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046564,GO:0071704 4.1.1.2 0.0000000000000000000000000000000000000000000000005494 176.0
HKD2_k127_716848_0 Methyltransferase small domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 334.0
HKD2_k127_716848_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K08313,K08314 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023 2.2.1.2 0.0000000000000000000000000000000000000000000000000001965 190.0
HKD2_k127_7171045_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 373.0
HKD2_k127_7171045_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 334.0
HKD2_k127_7171045_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 296.0
HKD2_k127_7171045_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000003464 239.0
HKD2_k127_7171045_5 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000001082 116.0
HKD2_k127_718288_0 Esterase of the alpha-beta hydrolase superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000005316 188.0
HKD2_k127_7183645_0 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000002476 143.0
HKD2_k127_7188305_0 Formate nitrite K21990 GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015318,GO:0015499,GO:0015711,GO:0015718,GO:0015724,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004043 286.0
HKD2_k127_7188305_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000001119 80.0
HKD2_k127_7193659_0 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 440.0
HKD2_k127_7193659_1 integral membrane protein - - - 0.000000000002452 69.0
HKD2_k127_7193659_2 Transposase - - - 0.00000002891 54.0
HKD2_k127_7196715_0 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 553.0
HKD2_k127_7196715_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 392.0
HKD2_k127_7204221_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001035 250.0
HKD2_k127_7204221_1 N-Acetylmuramoyl-L-alanine amidase K01207,K01447,K11066 - 3.2.1.52,3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000001876 235.0
HKD2_k127_7204221_2 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.000000000000000000000001458 104.0
HKD2_k127_7204221_3 Peptidase family S51 K13282 - 3.4.15.6 0.000000003721 66.0
HKD2_k127_7206247_0 Inner membrane component of T3SS, cytoplasmic domain - - - 7.443e-219 687.0
HKD2_k127_7206247_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 299.0
HKD2_k127_7206247_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 286.0
HKD2_k127_7206247_3 - - - - 0.0000000000000000000000000000000000000000000000000000009137 196.0
HKD2_k127_7211607_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000004683 233.0
HKD2_k127_7219311_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739,K01761 - 2.5.1.48,4.4.1.11 8.211e-204 638.0
HKD2_k127_7219311_1 Belongs to the 'phage' integrase family - - - 0.0000000000649 67.0
HKD2_k127_7219311_2 - - - - 0.00000001617 55.0
HKD2_k127_7219311_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00004962 53.0
HKD2_k127_7222753_0 Restriction endonuclease K07448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 318.0
HKD2_k127_7222753_1 Transposase K07494 - - 0.00000000000000000000000000000004441 128.0
HKD2_k127_7222753_2 FAD binding domain - - - 0.000000000000000000000000000000116 129.0
HKD2_k127_7222753_3 Transposase K07494 - - 0.0000000000000000000001496 98.0
HKD2_k127_7222753_4 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000004785 48.0
HKD2_k127_7226031_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 304.0
HKD2_k127_7226031_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000003435 239.0
HKD2_k127_7235528_0 4-amino-4-deoxy-L-arabinose transferase activity K00728 - 2.4.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 430.0
HKD2_k127_7241207_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 531.0
HKD2_k127_7241207_1 - - - - 0.00001879 54.0
HKD2_k127_7249637_0 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 542.0
HKD2_k127_7249637_2 DNA-binding transcription factor activity K04096 - - 0.000000000000000000000000000000000000647 141.0
HKD2_k127_7249637_3 pfam nudix K03574 - 3.6.1.55 0.0000000000000001814 85.0
HKD2_k127_7260220_0 ATPase AAA-2 domain protein K03696 - - 0.0 1554.0
HKD2_k127_7260220_1 PFAM RNA binding S1 domain protein K02945 - - 1.912e-219 693.0
HKD2_k127_7260220_2 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004192 237.0
HKD2_k127_7260220_3 ATPase AAA-2 domain protein K03696 - - 0.00000006132 53.0
HKD2_k127_7295124_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000003821 166.0
HKD2_k127_7295124_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000009623 99.0
HKD2_k127_7295124_2 InterPro IPR009057 - - - 0.00000000000000001273 83.0
HKD2_k127_7302159_0 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 558.0
HKD2_k127_7303045_0 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.000000000000000000000000000000000000000000000000000000000009198 225.0
HKD2_k127_7303045_1 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.0000003315 56.0
HKD2_k127_733100_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 8.71e-216 673.0
HKD2_k127_733100_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000002489 153.0
HKD2_k127_733100_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000004152 66.0
HKD2_k127_7334036_0 Protein of unknown function (DUF402) K07586 - - 0.0000000000000000000000000000000000000000000000003962 179.0
HKD2_k127_7334036_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) - - - 0.0000000000000009663 79.0
HKD2_k127_7353069_0 Major facilitator Superfamily - - - 5.917e-288 893.0
HKD2_k127_7353069_1 hydrolase activity, acting on ester bonds K22369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 408.0
HKD2_k127_7353069_2 transposition - - - 0.0000000000000000000003252 98.0
HKD2_k127_7353069_3 PFAM Iron permease FTR1 K07243 - - 0.0000006825 53.0
HKD2_k127_7353707_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003899 242.0
HKD2_k127_7353707_1 DNA-templated transcription, initiation K03088 - - 0.00000000000008237 80.0
HKD2_k127_7359502_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 398.0
HKD2_k127_7359502_1 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 367.0
HKD2_k127_7359502_2 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.0000000000000000000000000001485 115.0
HKD2_k127_7365728_0 Deoxyhypusine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 394.0
HKD2_k127_7365728_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.00000000000000000000000000000000000000000000000000000000000000001492 226.0
HKD2_k127_737841_0 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000001453 207.0
HKD2_k127_737841_1 Flavodoxin - - - 0.0000000000000000000002499 102.0
HKD2_k127_737841_2 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K02479 - - 0.000008339 49.0
HKD2_k127_7408064_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 401.0
HKD2_k127_742973_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K01497,K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 514.0
HKD2_k127_742973_1 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000004163 256.0
HKD2_k127_742973_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000231 197.0
HKD2_k127_742973_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000002866 189.0
HKD2_k127_742973_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000003473 100.0
HKD2_k127_7440270_0 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 450.0
HKD2_k127_7440270_1 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 332.0
HKD2_k127_7440270_2 Major Facilitator Superfamily K08167 - - 0.00000000000000000000000000000000000000000000000167 183.0
HKD2_k127_7446549_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 9.499e-263 818.0
HKD2_k127_7462307_0 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 431.0
HKD2_k127_7473489_0 Zinc-uptake complex component A periplasmic K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 361.0
HKD2_k127_7473489_1 PFAM ABC-3 protein K09816,K09819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 358.0
HKD2_k127_7473489_2 PFAM ABC transporter related K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 350.0
HKD2_k127_7473489_3 PFAM ABC-3 protein K09816,K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 316.0
HKD2_k127_7473489_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004044 246.0
HKD2_k127_7473489_5 AI-2E family transporter - - - 0.0000000000000000000000000002829 117.0
HKD2_k127_7475574_0 TIGRFAM DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 446.0
HKD2_k127_7501446_0 PFAM von Willebrand factor type A K07114 - - 7.573e-230 715.0
HKD2_k127_7501446_1 Protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 529.0
HKD2_k127_7501446_2 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 346.0
HKD2_k127_7501446_3 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009562 318.0
HKD2_k127_7501446_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000000000000008317 145.0
HKD2_k127_7501446_5 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000000000000000001688 121.0
HKD2_k127_7501446_6 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000001424 77.0
HKD2_k127_7502219_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 456.0
HKD2_k127_7515284_0 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 524.0
HKD2_k127_7515284_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 379.0
HKD2_k127_7515284_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000000000000004037 191.0
HKD2_k127_7517493_0 COGs COG3367 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 541.0
HKD2_k127_7517493_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000005713 136.0
HKD2_k127_7526121_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 330.0
HKD2_k127_7526121_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001011 249.0
HKD2_k127_7526121_2 cell adhesion involved in biofilm formation K07004,K12132 - 2.7.11.1 0.00000000000706 73.0
HKD2_k127_7526121_3 cell adhesion involved in biofilm formation K07004,K12132 - 2.7.11.1 0.00009228 53.0
HKD2_k127_7526121_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0002798 45.0
HKD2_k127_7537523_0 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 3.651e-203 638.0
HKD2_k127_7537523_1 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 336.0
HKD2_k127_7537523_2 Chromatin associated protein KTI12 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 308.0
HKD2_k127_7539988_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1111.0
HKD2_k127_7539988_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 432.0
HKD2_k127_7539988_2 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 341.0
HKD2_k127_7539988_3 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 342.0
HKD2_k127_7539988_5 Double zinc ribbon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 285.0
HKD2_k127_7539988_6 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001332 237.0
HKD2_k127_7563583_1 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 336.0
HKD2_k127_7563583_2 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 336.0
HKD2_k127_7563583_3 COG0526, thiol-disulfide isomerase and thioredoxins K03671 - - 0.00000000000000000000000000000000000001728 147.0
HKD2_k127_7563583_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000003293 141.0
HKD2_k127_7574564_0 PFAM magnesium chelatase K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 355.0
HKD2_k127_7574564_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K21479 - 2.1.1.272 0.0000000000000000000000000000000000000000000000000000000000000000001262 236.0
HKD2_k127_7574564_2 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000582 245.0
HKD2_k127_7612459_0 PFAM transglutaminase domain protein - - - 6.332e-263 833.0
HKD2_k127_7612459_1 Protein of unknown function DUF58 - - - 7.366e-196 616.0
HKD2_k127_7612459_2 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 541.0
HKD2_k127_7631837_0 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 304.0
HKD2_k127_7631837_1 WD40 repeat-like protein - - - 0.0000000000000001657 83.0
HKD2_k127_7638381_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 527.0
HKD2_k127_7638381_1 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003135 247.0
HKD2_k127_7638381_2 Cupin domain - - - 0.00000000000000000000000000000000003519 136.0
HKD2_k127_7663151_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.324e-309 954.0
HKD2_k127_7663151_1 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 371.0
HKD2_k127_7663151_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 340.0
HKD2_k127_7663151_3 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000005348 103.0
HKD2_k127_7668098_0 Cobalamin synthesis G C-terminus K02189 - 3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000001194 256.0
HKD2_k127_7668098_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K21479 - 2.1.1.272 0.0000000000000000000000000000000000000000000000000000000001779 208.0
HKD2_k127_7668098_2 Tetrapyrrole (Corrin/Porphyrin) Methylases K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000005291 197.0
HKD2_k127_7678292_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 450.0
HKD2_k127_7691202_1 protein histidine kinase activity K13924 - 2.1.1.80,3.1.1.61 0.000000001279 62.0
HKD2_k127_7708435_0 PFAM beta-lactamase domain protein - - - 3.961e-198 627.0
HKD2_k127_7708435_3 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.0000000000009751 69.0
HKD2_k127_7710572_0 - - - - 0.0000000000000000000000000000000000000000002358 164.0
HKD2_k127_7710572_1 - - - - 0.000000000000003193 87.0
HKD2_k127_7714784_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 1.037e-198 624.0
HKD2_k127_773284_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 543.0
HKD2_k127_773284_1 all-trans-retinol 13,14-reductase activity - - - 0.00000000000000000000000000000000000000000000000000002296 190.0
HKD2_k127_773348_0 PFAM Alcohol dehydrogenase GroES domain protein K00148 - 1.2.1.46 1.332e-217 679.0
HKD2_k127_7749832_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 362.0
HKD2_k127_7749832_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005644 282.0
HKD2_k127_7749832_3 GGDEF domain K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006382 256.0
HKD2_k127_7749832_4 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000003048 220.0
HKD2_k127_7749832_5 chemotaxis K03408 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009605,GO:0019904,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.0000000000000000000000000000000000000000000000000000004216 199.0
HKD2_k127_7749832_6 response regulator - - - 0.0000000000000000000000000000000000000000000002852 178.0
HKD2_k127_7750917_0 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 308.0
HKD2_k127_7750917_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0033554,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000414 198.0
HKD2_k127_7754577_0 Involved in the biosynthesis of porphyrin-containing compound - - - 3.651e-198 623.0
HKD2_k127_7754577_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004836 235.0
HKD2_k127_7754577_2 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.0000006437 54.0
HKD2_k127_7758710_0 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 318.0
HKD2_k127_7758710_1 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001332 271.0
HKD2_k127_7758710_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000006014 217.0
HKD2_k127_7775271_0 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000004432 201.0
HKD2_k127_7775271_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000001139 66.0
HKD2_k127_7789088_0 Dehydratase K06118 - 3.13.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 513.0
HKD2_k127_7789088_1 PFAM Pyrrolo-quinoline quinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 316.0
HKD2_k127_7793089_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 355.0
HKD2_k127_7793089_1 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 292.0
HKD2_k127_7793089_2 General stress protein K06884 - - 0.00000000000000000000000000000000000000000004809 162.0
HKD2_k127_7795010_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 416.0
HKD2_k127_7795010_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000141 267.0
HKD2_k127_7795010_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001971 251.0
HKD2_k127_7795633_0 hyperosmotic response K04065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 378.0
HKD2_k127_78089_0 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 303.0
HKD2_k127_78089_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009695 249.0
HKD2_k127_78089_2 - - - - 0.00000000000000000000000000007684 117.0
HKD2_k127_78089_3 Protein of unknown function DUF262 - - - 0.0000000000000001071 81.0
HKD2_k127_7818677_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins - - - 3.729e-258 803.0
HKD2_k127_7818677_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000000000002408 205.0
HKD2_k127_7818677_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000001018 169.0
HKD2_k127_7820203_0 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 375.0
HKD2_k127_7820203_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004423 252.0
HKD2_k127_7820203_2 acid phosphatase activity - - - 0.000000001481 60.0
HKD2_k127_7822825_0 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 328.0
HKD2_k127_7822825_1 regulatory protein LysR K21703 - - 0.000000000000000000000000000000000000000000000000000000000008403 218.0
HKD2_k127_7822825_2 Restriction endonuclease K07448 - - 0.000000000000000000000000000000000000004361 151.0
HKD2_k127_7822825_3 Transcriptional regulator, LysR K21703 - - 0.00000000000000000005764 95.0
HKD2_k127_7823012_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 580.0
HKD2_k127_7823012_2 FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits - - - 0.0000000000006492 72.0
HKD2_k127_7841049_0 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000002321 190.0
HKD2_k127_7841049_1 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000003757 149.0
HKD2_k127_7862937_0 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000002153 237.0
HKD2_k127_7862937_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000001989 193.0
HKD2_k127_7885486_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1078.0
HKD2_k127_7887403_0 MviN-like protein K03980 - - 0.00000000000000000000000000000000000002567 166.0
HKD2_k127_7889128_0 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 471.0
HKD2_k127_7889128_1 Putative heavy-metal-binding - - - 0.000000000000000000000000000000000000000000000000005432 182.0
HKD2_k127_7900819_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 622.0
HKD2_k127_7900819_1 N-Acetylmuramoyl-L-alanine amidase K01207,K01447,K11066 - 3.2.1.52,3.5.1.28 0.00000000000000000000000000000000000000000000000000000168 202.0
HKD2_k127_7922761_0 PFAM regulatory protein, MerR K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 334.0
HKD2_k127_7922761_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000004986 53.0
HKD2_k127_7922785_0 nitrite transmembrane transporter activity K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 392.0
HKD2_k127_7922785_1 Transcriptional regulator, MarR family - - - 0.00000000000000000000000000000000000000000000006505 172.0
HKD2_k127_7932210_0 PFAM TrkA-N domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 314.0
HKD2_k127_7932210_1 AMP binding - - - 0.0000000000000000000000000000000000000000000000001561 184.0
HKD2_k127_7932210_2 Arsenical pump membrane protein K03893 - - 0.00000000000000000000000000000001105 128.0
HKD2_k127_7948755_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 1.759e-211 668.0
HKD2_k127_7948755_1 PFAM ABC transporter related K02049,K15555,K15578 - - 2.324e-195 617.0
HKD2_k127_7948755_2 PFAM Haloacid dehalogenase domain protein hydrolase K02566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 342.0
HKD2_k127_7948755_3 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000004343 108.0
HKD2_k127_7954791_0 Alkaline and neutral invertase - - - 0.000000000000000000000000000000000000000000000000000000000000000002913 237.0
HKD2_k127_7959449_0 succinate dehydrogenase K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 430.0
HKD2_k127_7959449_1 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 323.0
HKD2_k127_7962776_0 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 6.136e-211 660.0
HKD2_k127_7962776_1 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005634 253.0
HKD2_k127_7962776_2 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000002921 96.0
HKD2_k127_7994910_0 HTH-like domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 306.0
HKD2_k127_7994910_1 transposase activity K07483,K07497 - - 0.000000000000000000000000000000000000001146 150.0
HKD2_k127_8022823_0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 314.0
HKD2_k127_8022823_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 310.0
HKD2_k127_8022823_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000000000006757 163.0
HKD2_k127_8022823_11 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001765 117.0
HKD2_k127_8022823_12 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000006684 90.0
HKD2_k127_8022823_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 304.0
HKD2_k127_8022823_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 303.0
HKD2_k127_8022823_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003951 265.0
HKD2_k127_8022823_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000001262 245.0
HKD2_k127_8022823_6 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008185 240.0
HKD2_k127_8022823_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000004618 226.0
HKD2_k127_8022823_8 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000006407 212.0
HKD2_k127_8022823_9 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000005495 195.0
HKD2_k127_8024596_0 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000538 206.0
HKD2_k127_8031492_0 Tricorn protease homolog K08676 - - 1.5e-323 1006.0
HKD2_k127_8031492_1 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001472 233.0
HKD2_k127_8031492_2 sequence-specific DNA binding - GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000002303 180.0
HKD2_k127_8031492_3 ACT domain K09707 - - 0.00073 44.0
HKD2_k127_8038272_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 582.0
HKD2_k127_8038272_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 489.0
HKD2_k127_8038272_2 TM2 domain - - - 0.0000000000000000000000000003889 121.0
HKD2_k127_8038272_3 Bacterial-like globin K06886 - - 0.000000000000000000000006439 103.0
HKD2_k127_8038272_6 Glycosyltransferase like family 2 - - - 0.0005787 45.0
HKD2_k127_8046445_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004258 287.0
HKD2_k127_8046445_1 COG3547, transposase and inactivated derivatives - - - 0.000000000000000004976 89.0
HKD2_k127_8046445_2 membrane protein (DUF2078) - - - 0.0005446 45.0
HKD2_k127_8053786_0 Atpase (Aaa K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 494.0
HKD2_k127_8053786_1 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000003648 130.0
HKD2_k127_8053786_2 - - - - 0.000005019 51.0
HKD2_k127_8054729_0 Aldo/keto reductase family K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 527.0
HKD2_k127_8054729_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000007397 173.0
HKD2_k127_8054729_2 - K18320 - - 0.0000000000000000000000000000002566 125.0
HKD2_k127_8054729_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000021 63.0
HKD2_k127_8060854_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 8.956e-204 638.0
HKD2_k127_8060854_1 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 581.0
HKD2_k127_8060854_2 Belongs to the 'phage' integrase family - - - 0.000000000006631 68.0
HKD2_k127_8060854_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000003473 63.0
HKD2_k127_8060854_4 Belongs to the 'phage' integrase family - - - 0.000001356 51.0
HKD2_k127_8066069_0 Alkaline and neutral invertase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008736 253.0
HKD2_k127_8070262_0 PFAM AMP-dependent synthetase and ligase - - - 9.02e-255 796.0
HKD2_k127_8070262_1 4'-phosphopantetheinyl transferase superfamily K00997,K06133 - 2.7.8.7 0.000000000000000000000000000000000000000000000000006512 189.0
HKD2_k127_8070262_2 thioesterase involved in non-ribosomal peptide biosynthesis K01071 - 3.1.2.21 0.0000000000005705 70.0
HKD2_k127_8074471_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1237.0
HKD2_k127_8074471_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 3.489e-243 755.0
HKD2_k127_8074471_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 488.0
HKD2_k127_8074471_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 303.0
HKD2_k127_8074471_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000001165 104.0
HKD2_k127_8074471_5 TM2 domain - - - 0.000000000000000000005073 101.0
HKD2_k127_8094134_0 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 445.0
HKD2_k127_8094134_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000003099 216.0
HKD2_k127_8099613_0 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000000000000000000001758 201.0
HKD2_k127_8099613_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K17940 - 1.14.13.182 0.000000000000000000000000000000000000000143 160.0
HKD2_k127_8101439_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 646.0
HKD2_k127_8101439_1 Transposase - - - 0.0000000000000000000000000000000000000000000001428 173.0
HKD2_k127_8101439_2 Transposase K07492 - - 0.0000000000000000000000000000000000000000003263 162.0
HKD2_k127_810283_0 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000007949 206.0
HKD2_k127_810283_1 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000001836 137.0
HKD2_k127_8106496_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 5.224e-239 751.0
HKD2_k127_8106496_1 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 616.0
HKD2_k127_8106496_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 500.0
HKD2_k127_8106496_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 448.0
HKD2_k127_8106496_4 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000000000000000004674 213.0
HKD2_k127_8106496_5 - - - - 0.00000000000000000000000000000008222 130.0
HKD2_k127_8106496_6 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000006116 76.0
HKD2_k127_8113543_0 ATP-grasp - - - 0.0000000000000000000000000001402 127.0
HKD2_k127_8113543_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000002924 126.0
HKD2_k127_8113543_2 PFAM Prenyltransferase squalene oxidase - - - 0.00002064 51.0
HKD2_k127_8117918_0 Belongs to the AAA ATPase family - - - 1.012e-232 736.0
HKD2_k127_8122657_0 Domain of unknown function (DUF929) - - - 0.000000000000000000000000000008507 124.0
HKD2_k127_8122657_1 Transposase - - - 0.000000000000000000002523 108.0
HKD2_k127_8143331_0 Putative zincin peptidase - - - 0.00000000000000000000000000000000000000000000000000000006388 202.0
HKD2_k127_8143331_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000001773 190.0
HKD2_k127_8145584_0 Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde K05829 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 541.0
HKD2_k127_8145584_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 522.0
HKD2_k127_8145584_2 Belongs to the RimK family K05827 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 459.0
HKD2_k127_8145584_3 Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine K05830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 449.0
HKD2_k127_8145584_4 Belongs to the acetylglutamate kinase family. LysZ subfamily K05828 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 362.0
HKD2_k127_8145584_5 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000003873 156.0
HKD2_k127_8145584_6 ABC-2 family transporter protein - - - 0.0000000000000000000000000004048 124.0
HKD2_k127_8145584_7 TIGRFAM lysine biosynthesis protein LysW K05826 - - 0.000000000000000000005429 93.0
HKD2_k127_8145584_8 - - - - 0.00005643 54.0
HKD2_k127_8145584_9 MacB-like periplasmic core domain - - - 0.0005513 51.0
HKD2_k127_8176138_0 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 451.0
HKD2_k127_8176138_1 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000006495 104.0
HKD2_k127_8179031_0 N,N-dimethylaniline monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 304.0
HKD2_k127_8179031_1 ATP-grasp domain - - - 0.000000000000000000000000000103 130.0
HKD2_k127_8179031_2 Polysaccharide deacetylase - - - 0.0000004655 57.0
HKD2_k127_8197422_0 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000002751 197.0
HKD2_k127_8197422_1 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000003913 168.0
HKD2_k127_8197422_2 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000006497 168.0
HKD2_k127_8197422_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000005244 81.0
HKD2_k127_8204150_1 Transposase - - - 0.000003036 50.0
HKD2_k127_8219046_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 7.224e-312 961.0
HKD2_k127_8219046_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.178e-244 758.0
HKD2_k127_8219046_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000009011 238.0
HKD2_k127_8219046_3 acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000002464 222.0
HKD2_k127_8220077_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 7.962e-196 640.0
HKD2_k127_8255225_0 - - - - 0.000000000000000000000000000000000000000000000000001034 206.0
HKD2_k127_8258669_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 445.0
HKD2_k127_8258669_1 cyclic-guanylate-specific phosphodiesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 382.0
HKD2_k127_8272264_0 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 454.0
HKD2_k127_8272264_1 PFAM ABC transporter related K06147 - - 0.000000000000000000000000000000000000000000000009762 175.0
HKD2_k127_8273459_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00006446 47.0
HKD2_k127_828260_0 PFAM peptidase S58, DmpA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 424.0
HKD2_k127_828260_1 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000113 144.0
HKD2_k127_8284494_0 His Kinase A (phosphoacceptor) domain - - - 4.088e-227 724.0
HKD2_k127_8288902_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 619.0
HKD2_k127_8308094_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 457.0
HKD2_k127_8308094_1 PFAM transposase mutator type - - - 0.0000000000000000000000000000000000002024 141.0
HKD2_k127_8308094_2 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000003028 140.0
HKD2_k127_8308094_3 bacterial-type flagellum-dependent cell motility K01317 - 3.4.21.10 0.0000000000000003456 87.0
HKD2_k127_8308954_0 PHP domain protein K02347 - - 1.587e-211 664.0
HKD2_k127_8308954_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000008875 196.0
HKD2_k127_8308954_2 Glycosyltransferase Family 4 - - - 0.000000000000000000000000003795 111.0
HKD2_k127_8313166_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183,K11189 - 2.7.1.202,2.7.3.9 8.867e-230 728.0
HKD2_k127_8313166_1 Periplasmic binding protein LacI transcriptional regulator K03435 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 459.0
HKD2_k127_8324510_0 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 326.0
HKD2_k127_8337880_0 RNA methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007691 256.0
HKD2_k127_8337880_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000001008 139.0
HKD2_k127_8337880_2 RNA methylase - - - 0.00000000000000000000003295 104.0
HKD2_k127_8337880_3 - - - - 0.000007389 48.0
HKD2_k127_8338320_0 Pyridine nucleotide-disulphide oxidoreductase dimerisation region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 590.0
HKD2_k127_8338320_1 S-acyltransferase activity K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 385.0
HKD2_k127_8353596_0 cytosine transport - - - 1.957e-257 801.0
HKD2_k127_8354119_0 Protein of unknown function, DUF255 K06888 - - 0.0 1022.0
HKD2_k127_8354119_1 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000004463 224.0
HKD2_k127_8357752_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 1.23e-203 648.0
HKD2_k127_8357752_1 TIGRFAM transposase, IS605 OrfB family, central region K07496 - - 0.0000000000000000000000000000000000000000002207 159.0
HKD2_k127_8360958_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.008e-195 619.0
HKD2_k127_8360958_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000001594 121.0
HKD2_k127_8379032_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 383.0
HKD2_k127_8379032_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001691 242.0
HKD2_k127_8379032_2 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000001144 249.0
HKD2_k127_8379032_4 PFAM pentapeptide repeat protein - - - 0.000000000000000000002024 103.0
HKD2_k127_8380338_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001933 292.0
HKD2_k127_8380338_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000003124 232.0
HKD2_k127_8380338_2 histone H2A K63-linked ubiquitination - - - 0.00000000000000001646 96.0
HKD2_k127_8381964_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000004101 213.0
HKD2_k127_8381964_1 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000000000001872 189.0
HKD2_k127_8381964_2 COGs COG0859 ADP-heptose LPS heptosyltransferase K02841,K02843 - - 0.0000000000004929 73.0
HKD2_k127_8384716_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 426.0
HKD2_k127_8384716_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000003269 165.0
HKD2_k127_8384881_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 315.0
HKD2_k127_8386990_0 Peptidase dimerisation domain K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 444.0
HKD2_k127_8386990_2 - - - - 0.000000000000000000000000000001382 126.0
HKD2_k127_8402844_0 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 549.0
HKD2_k127_8402844_1 Serine threonine protein kinase K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 525.0
HKD2_k127_8402844_2 Glyoxalase-like domain - - - 0.000005437 53.0
HKD2_k127_8404597_0 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000003525 233.0
HKD2_k127_8404597_1 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000001027 215.0
HKD2_k127_8404597_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000001019 207.0
HKD2_k127_8404597_3 PFAM Transposase IS66 family - - - 0.00000189 50.0
HKD2_k127_8405747_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 413.0
HKD2_k127_8405747_1 Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000002309 213.0
HKD2_k127_8405747_2 ADP-ribosylation factor family K06883 - - 0.000000000000000000000002501 102.0
HKD2_k127_8405747_3 Transposase - - - 0.00000000000000004537 81.0
HKD2_k127_8410839_0 COG0438 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000007328 195.0
HKD2_k127_8410839_1 Glycosyl transferase 4-like - - - 0.00000000000000305 77.0
HKD2_k127_8418282_0 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 455.0
HKD2_k127_8426739_0 PFAM GAF domain protein K01628,K03406,K21009 - 4.1.2.17 4.845e-255 803.0
HKD2_k127_8426739_1 cytosine transport K03457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 515.0
HKD2_k127_8426739_2 cytosine transport K03457 - - 0.00000000000000000000000000000000000004456 146.0
HKD2_k127_8426739_3 TIGRFAM glycosyltransferase, MGT family - - - 0.0000000000000003509 81.0
HKD2_k127_8426739_4 TIGRFAM glycosyltransferase, MGT family - - - 0.0000000006944 63.0
HKD2_k127_8472409_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 400.0
HKD2_k127_8472409_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 352.0
HKD2_k127_8472409_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 327.0
HKD2_k127_8487326_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.297e-259 805.0
HKD2_k127_8487326_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 2.486e-225 703.0
HKD2_k127_8501288_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 9.046e-196 618.0
HKD2_k127_8501288_1 aminotransferase class I and II K10907 - - 9.995e-195 613.0
HKD2_k127_8501288_2 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000002149 196.0
HKD2_k127_8506038_0 DNA mediated transformation K04096,K08312 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019144,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872 - 0.00000000000000000000000000000000001289 146.0
HKD2_k127_8514098_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 5.484e-209 657.0
HKD2_k127_8517999_0 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 441.0
HKD2_k127_8517999_1 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000004155 223.0
HKD2_k127_8517999_2 phosphatase activity K01560,K07025 - 3.8.1.2 0.00000000000000000000000000000000000000000000007658 173.0
HKD2_k127_8526306_0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 377.0
HKD2_k127_8526306_1 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000001901 242.0
HKD2_k127_8526654_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00166,K00167,K11381 - 1.2.4.4 0.0 1170.0
HKD2_k127_8526654_1 PFAM peptidase M16 domain protein - - - 2.719e-197 623.0
HKD2_k127_8526654_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 529.0
HKD2_k127_8526654_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000002611 243.0
HKD2_k127_8526654_4 Double zinc ribbon - - - 0.000000000000000000000000000000000000000000000000000000000000007608 223.0
HKD2_k127_8526654_5 PFAM Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000000000000002516 173.0
HKD2_k127_8529847_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 355.0
HKD2_k127_8529847_1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000000000000000000000000000000000000000000000000000000000004345 211.0
HKD2_k127_8529847_2 succinate dehydrogenase, cytochrome K00241 - - 0.000000000000000000000000000000000000000000000008695 176.0
HKD2_k127_8542030_0 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 398.0
HKD2_k127_8542030_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 398.0
HKD2_k127_8542030_2 PFAM UbiA prenyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006388 253.0
HKD2_k127_8542030_3 RNA-binding protein containing a PIN domain K06962 - - 0.0000000000000000000000000000000000000003898 154.0
HKD2_k127_8559806_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 550.0
HKD2_k127_8559806_1 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 451.0
HKD2_k127_8559806_2 Bacterial PH domain - - - 0.0000000000000000001761 96.0
HKD2_k127_8559806_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000263 52.0
HKD2_k127_8576441_0 Putative methyltransferase - - - 0.00000000000000000000000000000000000000000000000959 184.0
HKD2_k127_8576441_1 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000002105 142.0
HKD2_k127_8576441_2 methyltransferase - - - 0.000000000000000000000000000002916 132.0
HKD2_k127_8576441_3 Putative methyltransferase - - - 0.000000000000000000000003605 113.0
HKD2_k127_8576441_4 methyltransferase - - - 0.0000000000000004738 88.0
HKD2_k127_8606788_0 PFAM amine oxidase - - - 2.821e-214 671.0
HKD2_k127_8610131_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 1.065e-196 618.0
HKD2_k127_8610131_1 Iron-sulfur cluster binding protein K18929 - - 0.0000000000000000000000000000000000000001429 151.0
HKD2_k127_8610131_2 Iron-sulfur cluster binding protein K18929 - - 0.00000000000001207 74.0
HKD2_k127_8629675_0 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 366.0
HKD2_k127_8629675_1 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000001607 216.0
HKD2_k127_8631689_0 PFAM MMPL domain protein K06994 - - 4.081e-216 678.0
HKD2_k127_8631689_1 Lipocalin-like domain - - - 0.0000931 46.0
HKD2_k127_8634855_0 nitrite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 497.0
HKD2_k127_8634855_1 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000001988 167.0
HKD2_k127_8650423_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 1.652e-229 716.0
HKD2_k127_8650423_1 SMART protein phosphatase 2C domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 346.0
HKD2_k127_8650423_2 Serine threonine protein kinase K08884 - 2.7.11.1 0.00000000000000000000000000005513 118.0
HKD2_k127_865105_0 COGs COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 503.0
HKD2_k127_865105_1 negative regulation of transcription, DNA-templated K21600 - - 0.0000000000000000000003014 98.0
HKD2_k127_8653733_0 PFAM CoA-binding domain protein K06929 - - 0.00000000000000000000000000001654 119.0
HKD2_k127_8701372_0 TIGRFAM geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 510.0
HKD2_k127_8701372_1 spheroidene monooxygenase K09847 - 1.14.15.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 319.0
HKD2_k127_8707011_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 539.0
HKD2_k127_8707011_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000001318 177.0
HKD2_k127_8707011_2 Domain of unknown function (DUF4397) - - - 0.000000002739 59.0
HKD2_k127_8714900_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 481.0
HKD2_k127_8714900_1 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000007964 152.0
HKD2_k127_8722104_0 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004531 264.0
HKD2_k127_8722104_1 Gaf domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008503 265.0
HKD2_k127_872794_0 NurA - - - 3.585e-196 617.0
HKD2_k127_872794_1 CpXC protein - - - 0.00000002666 55.0
HKD2_k127_873673_0 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000006598 168.0
HKD2_k127_873673_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000001447 145.0
HKD2_k127_873673_2 PFAM Rh family protein ammonium transporter K03320 - - 0.0000000000000000000000000000574 117.0
HKD2_k127_875704_0 Aldehyde dehydrogenase family - - - 0.0 1264.0
HKD2_k127_875704_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - - 3.789e-315 973.0
HKD2_k127_875704_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 419.0
HKD2_k127_875704_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 355.0
HKD2_k127_875704_4 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 352.0
HKD2_k127_8761914_0 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000005665 237.0
HKD2_k127_8761914_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000003598 102.0
HKD2_k127_8775098_0 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 302.0
HKD2_k127_8775098_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000272 278.0
HKD2_k127_8775098_2 Putative ATPase subunit of terminase (gpP-like) - - - 0.000000000000000000000000000000000000000000000000001052 184.0
HKD2_k127_8775098_3 tRNA (guanine-N2-)-methyltransferase activity K00563,K00571,K07319,K18896 - 2.1.1.156,2.1.1.187,2.1.1.72 0.000000002081 59.0
HKD2_k127_8806168_1 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000001597 208.0
HKD2_k127_8815935_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 364.0
HKD2_k127_8815935_1 - - - - 0.00000000000000000000000000000000000000000000001425 172.0
HKD2_k127_8819167_0 NYN domain - - - 0.000159 53.0
HKD2_k127_8819762_0 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 386.0
HKD2_k127_8819762_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008494 244.0
HKD2_k127_882599_0 - K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 297.0
HKD2_k127_8829403_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 549.0
HKD2_k127_8829403_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000985 104.0
HKD2_k127_8832583_0 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000002075 175.0
HKD2_k127_8832583_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000005583 158.0
HKD2_k127_8855814_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.357e-228 712.0
HKD2_k127_8861054_0 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 464.0
HKD2_k127_8861054_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 410.0
HKD2_k127_8862628_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 9.032e-233 727.0
HKD2_k127_8862628_1 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000004636 131.0
HKD2_k127_8862628_2 beta-lactamase domain protein - - - 0.000000000000000000005991 92.0
HKD2_k127_8867129_0 SnoaL-like domain - - - 0.000000000000000000000000000000000001504 141.0
HKD2_k127_8867129_1 - K09932 - - 0.0000000000000005323 79.0
HKD2_k127_8867129_2 high-affinity ferrous iron transmembrane transporter activity K07243 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000003096 59.0
HKD2_k127_8869905_0 PFAM peptidase M20 - - - 0.000000000000000000000000000000000001421 152.0
HKD2_k127_887231_0 Protein of unknown function (DUF4012) - - - 4.501e-233 749.0
HKD2_k127_887231_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 2.221e-214 674.0
HKD2_k127_8922205_0 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 409.0
HKD2_k127_8922205_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 379.0
HKD2_k127_8922205_2 PFAM PfkB domain protein K00847,K00852 - 2.7.1.15,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000001343 247.0
HKD2_k127_8922205_3 N-acetylglucosaminylinositol deacetylase activity K18455 - 3.5.1.115 0.0000000000000000001074 91.0
HKD2_k127_8922728_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 434.0
HKD2_k127_8958905_0 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 311.0
HKD2_k127_8958905_1 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000008057 147.0
HKD2_k127_8968439_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0 1163.0
HKD2_k127_8968439_1 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 9.146e-220 689.0
HKD2_k127_8977233_0 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 331.0
HKD2_k127_8981548_0 Archaeal transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 400.0
HKD2_k127_8981548_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 298.0
HKD2_k127_8981548_2 heme oxygenase (decyclizing) activity - - - 0.0000000000000000000000000000000000000000000004539 168.0
HKD2_k127_8987461_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 349.0
HKD2_k127_8987461_1 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002008 287.0
HKD2_k127_8990719_0 Terminase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 600.0
HKD2_k127_9021392_0 peptidyl-tyrosine sulfation - - - 3.324e-213 686.0
HKD2_k127_9021392_1 phosphatidylinositol metabolic process K13671 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 606.0
HKD2_k127_9021392_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 574.0
HKD2_k127_9021392_3 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 419.0
HKD2_k127_9021392_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 381.0
HKD2_k127_9021392_6 Homeodomain-like domain - - - 0.0000000000000000000000000000000001076 138.0
HKD2_k127_9021392_7 Portal protein - - - 0.000000000000000000000000000000001334 136.0
HKD2_k127_9021392_8 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.0001193 46.0
HKD2_k127_9022446_0 glycyl-radical enzyme activating activity - - - 2.512e-212 667.0
HKD2_k127_9022446_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 567.0
HKD2_k127_9022446_2 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 535.0
HKD2_k127_9022446_4 acetyltransferase - - - 0.000000000000000000000000000000000000000000000007693 181.0
HKD2_k127_9025629_0 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 462.0
HKD2_k127_9025629_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009059 279.0
HKD2_k127_9025629_2 - - - - 0.0000000000000000000000000000000000001137 145.0
HKD2_k127_9025629_3 Transposase - - - 0.000008327 50.0
HKD2_k127_9034057_0 protein histidine kinase activity K14980 - 2.7.13.3 1.382e-270 856.0
HKD2_k127_9034057_1 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 345.0
HKD2_k127_9034057_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000002483 199.0
HKD2_k127_9065494_0 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 531.0
HKD2_k127_9065494_1 Polysaccharide biosynthesis protein - - - 0.000000000000006655 76.0
HKD2_k127_9065494_2 phosphorelay signal transduction system - - - 0.0004585 44.0
HKD2_k127_9068307_0 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000002179 163.0
HKD2_k127_9097413_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001779 280.0
HKD2_k127_9097413_1 phosphorelay signal transduction system K03413 - - 0.000000000000000000000000000000000000000000000003527 177.0
HKD2_k127_9097413_2 ECF transporter, substrate-specific component - - - 0.000000000000000003202 86.0
HKD2_k127_9102337_0 Isocitrate/isopropylmalate dehydrogenase - - - 3.734e-244 761.0
HKD2_k127_9102337_1 Reversible hydration of carbon dioxide - - - 0.00000001392 55.0
HKD2_k127_9104383_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.042e-314 975.0
HKD2_k127_9104383_1 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 310.0
HKD2_k127_9104383_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001278 259.0
HKD2_k127_9104383_3 negative regulation of transcription, DNA-templated - - - 0.00000004314 55.0
HKD2_k127_9105147_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 307.0
HKD2_k127_9108801_0 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 446.0
HKD2_k127_9108801_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 429.0
HKD2_k127_9110513_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000003705 232.0
HKD2_k127_9147987_0 Histidine kinase - - - 5.603e-238 754.0
HKD2_k127_9149427_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 293.0
HKD2_k127_9149427_1 signal-transduction protein containing cAMP-binding and CBS domains K00384 - 1.8.1.9 0.0000000000000000000000000000000000000003262 150.0
HKD2_k127_915393_0 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 6.072e-268 836.0
HKD2_k127_9165800_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1482.0
HKD2_k127_9177385_0 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K07027,K14205 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 403.0
HKD2_k127_9177385_1 Cytochrome P450 K14370 GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0019748,GO:0020037,GO:0030638,GO:0030639,GO:0033067,GO:0033068,GO:0036094,GO:0044237,GO:0044249,GO:0044550,GO:0046483,GO:0046906,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901363,GO:1901576 1.14.13.154 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 400.0
HKD2_k127_9177385_2 polysaccharide biosynthetic process K00655,K00721 - 2.3.1.51,2.4.1.83 0.0000000000000000000000000000000000000000000000000000000004913 206.0
HKD2_k127_9182556_0 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000003613 263.0
HKD2_k127_9182556_1 B-1 B cell differentiation - - - 0.0000000000000000000000000000000000000000000000000000000008036 205.0
HKD2_k127_9184507_0 histidine kinase A domain protein K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 296.0
HKD2_k127_9184507_1 Belongs to the globin family - - - 0.000002141 53.0
HKD2_k127_9190635_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0 1103.0
HKD2_k127_919651_0 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 583.0
HKD2_k127_919651_1 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 538.0
HKD2_k127_919651_2 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 360.0
HKD2_k127_9211803_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 8.864e-309 949.0
HKD2_k127_9213241_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 511.0
HKD2_k127_9221069_0 histidine kinase A domain protein - - - 2.116e-210 666.0
HKD2_k127_9221069_1 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 542.0
HKD2_k127_9221069_2 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 496.0
HKD2_k127_9221069_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 433.0
HKD2_k127_9221069_4 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 432.0
HKD2_k127_9221069_5 regulation of circadian rhythm - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 384.0
HKD2_k127_9221069_6 nUDIX hydrolase K01515,K03574,K19710 - 2.7.7.53,3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000004594 248.0
HKD2_k127_9221069_7 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000001366 146.0
HKD2_k127_9222933_0 3-dehydroquinate synthase K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 477.0
HKD2_k127_9222933_1 hydrolase activity, acting on ester bonds K07051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 447.0
HKD2_k127_9222933_2 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001405 259.0
HKD2_k127_9222933_3 - - - - 0.00000000000000000000000000427 113.0
HKD2_k127_9253571_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 549.0
HKD2_k127_9253571_1 endonuclease activity K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 458.0
HKD2_k127_9262063_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1476.0
HKD2_k127_9275494_0 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 308.0
HKD2_k127_9275494_1 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000002189 174.0
HKD2_k127_9275494_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000001906 79.0
HKD2_k127_9275494_3 amine dehydrogenase activity - - - 0.00000000000009435 75.0
HKD2_k127_9275494_4 Phospholipase_D-nuclease N-terminal - - - 0.00000000002218 69.0
HKD2_k127_928917_0 Uncharacterised protein family (UPF0261) - - - 1.654e-197 623.0
HKD2_k127_928917_1 Phosphoenolpyruvate hydrolase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 488.0
HKD2_k127_928917_2 - - - - 0.000000000000000005764 85.0
HKD2_k127_928917_3 Transposase DDE domain - - - 0.0008835 45.0
HKD2_k127_9290873_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.092e-228 714.0
HKD2_k127_9290873_1 - - - - 0.000000000000000000000000001184 127.0
HKD2_k127_9290873_2 - - - - 0.000000001742 62.0
HKD2_k127_9296569_0 PFAM transferase hexapeptide repeat containing protein K16881 - 2.7.7.13,5.4.2.8 0.0 1371.0
HKD2_k127_9296569_1 InterPro IPR007367 - - - 0.0000000000000000000000000000000000000007086 149.0
HKD2_k127_9314920_0 Tricorn protease homolog K08676 - - 0.0 1639.0
HKD2_k127_9314920_1 PFAM sugar transferase - - - 4.542e-227 713.0
HKD2_k127_9314920_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 527.0
HKD2_k127_9314920_3 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 517.0
HKD2_k127_9314920_4 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 356.0
HKD2_k127_9314920_5 Peptidase family M20/M25/M40 - - - 0.00000000000000000000000000000002552 128.0
HKD2_k127_9323980_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 409.0
HKD2_k127_9323980_1 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 400.0
HKD2_k127_9323980_2 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002039 249.0
HKD2_k127_9338594_0 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000002274 204.0
HKD2_k127_9338594_1 PFAM ATPase associated with various cellular activities K03924 - - 0.000000000000005612 76.0
HKD2_k127_9391017_0 PFAM ABC transporter related K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 359.0
HKD2_k127_9391017_1 Putative adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 299.0
HKD2_k127_9406629_0 Serine threonine protein kinase - - - 5.848e-279 880.0
HKD2_k127_9419899_0 Nickel-dependent hydrogenase - - - 1.903e-211 664.0
HKD2_k127_9419899_1 coenzyme F420 hydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 390.0
HKD2_k127_9419899_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 377.0
HKD2_k127_9419899_3 Hydrogenase maturation protease - - - 0.000000004826 59.0
HKD2_k127_9423361_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1035.0
HKD2_k127_9423361_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 567.0
HKD2_k127_9423361_3 GYD domain - - - 0.000000000000000000000000000001473 124.0
HKD2_k127_9423361_5 - - - - 0.00000000002255 68.0
HKD2_k127_9426384_0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000005754 187.0
HKD2_k127_9426384_1 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000007974 124.0
HKD2_k127_9428225_0 PFAM glycosyl transferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 469.0
HKD2_k127_9428225_1 PFAM molybdopterin binding domain - - - 0.00000000000000000000000000005628 122.0
HKD2_k127_9428225_2 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000001237 66.0
HKD2_k127_9449060_0 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 373.0
HKD2_k127_9455473_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 565.0
HKD2_k127_9455473_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 432.0
HKD2_k127_9455473_3 histone H2A K63-linked ubiquitination K21397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004203 250.0
HKD2_k127_9455473_4 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000000302 177.0
HKD2_k127_9455473_6 TIGRFAM DNA binding domain - - - 0.000000000000000000000000000007511 120.0
HKD2_k127_9455473_7 Cation transport regulator - - - 0.0000000000000006002 87.0
HKD2_k127_9459988_0 PFAM Phosphomethylpyrimidine kinase type-1 K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 366.0
HKD2_k127_9459988_1 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 351.0
HKD2_k127_9459988_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007851 274.0
HKD2_k127_9463364_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 436.0
HKD2_k127_9463364_1 Transposase - - - 0.00000000000000000000000000000000000000000000000000004033 190.0
HKD2_k127_9469734_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.905e-250 780.0
HKD2_k127_9469734_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000002818 218.0
HKD2_k127_9469734_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000002483 98.0
HKD2_k127_9469734_3 CAAX protease self-immunity K07052 - - 0.0003504 43.0
HKD2_k127_9472093_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000001026 240.0
HKD2_k127_9472093_1 phosphorelay signal transduction system K03413 - - 0.0000000000000000000000000000000000000000000000000000000001757 220.0
HKD2_k127_9472093_2 Phage shock protein A K03969 - - 0.000000000000000000000000000000000000000000000004345 183.0
HKD2_k127_947299_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 3.676e-269 831.0
HKD2_k127_947299_1 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 312.0
HKD2_k127_947299_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004775 269.0
HKD2_k127_947299_3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000000000000000000000000000000000000003929 233.0
HKD2_k127_947299_4 urea catabolic process K01430 - 3.5.1.5 0.00000000000000000000000000000000000000000000002681 171.0
HKD2_k127_947299_5 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.00000000000000000000000000000000000000000000005811 171.0
HKD2_k127_9474994_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 1.623e-215 677.0
HKD2_k127_9477144_0 Hydantoinaseoxoprolinase domain protein K01473 - 3.5.2.14 6.088e-297 923.0
HKD2_k127_9477144_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 1.148e-271 843.0
HKD2_k127_9508756_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000000000000000000001174 239.0
HKD2_k127_9508756_1 Transposase, IS605 OrfB family K07496 - - 0.000000000000000000000000000000000000000000000000003724 183.0
HKD2_k127_9508756_2 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.00001186 57.0
HKD2_k127_9509977_0 cell adhesion involved in biofilm formation K07004,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000444 192.0
HKD2_k127_9510435_1 - - - - 0.000000000002857 72.0
HKD2_k127_9534567_0 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 460.0
HKD2_k127_9574035_0 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 556.0
HKD2_k127_9574035_1 PFAM zinc finger, SWIM domain protein - - - 0.000000000000000000000000000000000000000000000000000001914 192.0
HKD2_k127_9578440_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.463e-267 827.0
HKD2_k127_9578440_1 PFAM Transketolase central region K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 552.0
HKD2_k127_9578440_2 PFAM dehydrogenase, E1 component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 516.0
HKD2_k127_9578440_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 344.0
HKD2_k127_9578997_0 carboxylate-amine ligase domain protein - - - 2.575e-209 657.0
HKD2_k127_9578997_1 Transposase domain (DUF772) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 522.0
HKD2_k127_9578997_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 456.0
HKD2_k127_9578997_3 glycolate biosynthetic process K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000644 262.0
HKD2_k127_9580151_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 375.0
HKD2_k127_9580151_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000004375 232.0
HKD2_k127_9580151_2 translation release factor activity - - - 0.0000000000000000000396 92.0
HKD2_k127_9580151_3 - - - - 0.000000000000000002093 86.0
HKD2_k127_9589653_0 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 321.0
HKD2_k127_9589653_1 ECF transporter, substrate-specific component - - - 0.0000000000000000000000000000000000000000000000000000000000000000001063 236.0
HKD2_k127_9600664_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 455.0
HKD2_k127_9600664_2 Transposase, IS605 OrfB family K07496 - - 0.000000000000000000000000000000000000000000000000000000001313 203.0
HKD2_k127_9613815_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 2.331e-224 699.0
HKD2_k127_9613815_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 8.059e-213 673.0
HKD2_k127_9613815_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 380.0
HKD2_k127_9618138_0 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 326.0
HKD2_k127_9618138_1 BioY family - - - 0.00000000000000000000000000000000000000000000000000000002711 205.0
HKD2_k127_9624043_0 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 591.0
HKD2_k127_9624043_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 367.0
HKD2_k127_9624043_2 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 350.0
HKD2_k127_9624043_3 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000001186 220.0
HKD2_k127_9625588_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 2.453e-280 869.0
HKD2_k127_9625588_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 321.0
HKD2_k127_9625588_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 290.0
HKD2_k127_9625588_3 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.00000000000000000000000000000000000000000000000000000000001495 211.0
HKD2_k127_9625588_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000002463 171.0
HKD2_k127_9625588_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000003926 120.0
HKD2_k127_9633460_0 Putative membrane peptidase family (DUF2324) - - - 0.00000000000000000000000000000000000000000000000000001437 197.0
HKD2_k127_9633460_1 Ring-cleavage extradiol dioxygenase - - - 0.0000000000000000000000000000000000000000000004276 175.0
HKD2_k127_9634059_0 PFAM AMP-dependent synthetase and ligase K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 474.0
HKD2_k127_9634059_1 nitrite transmembrane transporter activity K02575 - - 0.000000000000000000000001666 111.0
HKD2_k127_9639304_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 6.096e-308 960.0
HKD2_k127_9639304_1 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 489.0
HKD2_k127_9639304_2 Transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 431.0
HKD2_k127_9639304_3 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000000000003955 209.0
HKD2_k127_9660678_0 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 378.0
HKD2_k127_9660678_1 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000001899 243.0
HKD2_k127_9676475_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.0 1017.0
HKD2_k127_9676475_1 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000005182 243.0
HKD2_k127_9676475_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000004236 180.0
HKD2_k127_968744_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 476.0
HKD2_k127_968744_1 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000001538 216.0
HKD2_k127_968744_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.00000000000000000000000000000000000000000000003272 172.0
HKD2_k127_9714852_0 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000000000000000000000000000000000000000000552 173.0
HKD2_k127_9714852_1 - - - - 0.00000000000000000000000006704 109.0
HKD2_k127_9725425_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 601.0
HKD2_k127_9744806_0 peptidase dimerisation domain protein - - - 1.561e-228 715.0
HKD2_k127_9744806_1 PFAM peptidase M20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 424.0
HKD2_k127_9744806_2 PFAM ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 387.0
HKD2_k127_9744806_3 water channel activity K02440,K06188,K09874 - - 0.00000000000000000000001665 102.0
HKD2_k127_9744806_4 - - - - 0.00000000000006698 75.0
HKD2_k127_9768731_0 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 338.0
HKD2_k127_9768731_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000462 287.0
HKD2_k127_9768731_2 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000002768 167.0
HKD2_k127_9775869_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 590.0
HKD2_k127_9775869_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 410.0
HKD2_k127_9775869_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 367.0
HKD2_k127_9775869_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 359.0
HKD2_k127_9775869_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 316.0
HKD2_k127_9775869_5 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 306.0
HKD2_k127_9775869_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005629 249.0
HKD2_k127_9775869_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000006154 224.0
HKD2_k127_9775869_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000001029 139.0
HKD2_k127_9775869_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001029 139.0
HKD2_k127_9787201_0 Predicted membrane protein (DUF2079) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 612.0
HKD2_k127_9787201_1 membrane-bound metal-dependent K07038 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0031668,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 306.0
HKD2_k127_9787201_2 YGGT family - - - 0.00000000000000000000000000000000000000000000000000000000002838 210.0
HKD2_k127_9809775_0 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000001452 194.0
HKD2_k127_9809775_2 ABC-2 family transporter protein - - - 0.00000000003237 64.0
HKD2_k127_9827615_0 homoserine kinase activity K01091,K03430,K05306 GO:0003674,GO:0003824 2.6.1.37,3.1.3.18,3.11.1.1 2.411e-292 916.0
HKD2_k127_9827615_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 516.0
HKD2_k127_9827615_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000005151 75.0
HKD2_k127_983164_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 573.0
HKD2_k127_983164_1 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 302.0
HKD2_k127_983164_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000005488 243.0
HKD2_k127_9863571_0 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 328.0
HKD2_k127_9863571_1 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 301.0
HKD2_k127_9863928_0 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 350.0
HKD2_k127_9863928_1 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 303.0
HKD2_k127_9885214_0 conserved protein (DUF2156) K14205 - 2.3.2.3 2.527e-226 714.0
HKD2_k127_9900145_0 PFAM penicillin-binding protein transpeptidase K05364 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 287.0
HKD2_k127_9900145_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000003726 113.0
HKD2_k127_9919256_0 PFAM penicillin-binding protein transpeptidase K05364 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 578.0
HKD2_k127_9919256_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 240.0
HKD2_k127_9919256_2 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000003807 215.0
HKD2_k127_992828_0 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 475.0
HKD2_k127_992828_1 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 449.0
HKD2_k127_9949675_0 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001851 280.0
HKD2_k127_9949675_2 ECF sigma factor - - - 0.0000005909 54.0
HKD2_k127_9959091_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 3.354e-312 962.0
HKD2_k127_9959091_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000012 179.0
HKD2_k127_9959091_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000005617 84.0
HKD2_k127_9966437_0 S-adenosylhomocysteine deaminase activity K05603 - 3.5.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 532.0
HKD2_k127_9966437_1 Tricorn protease homolog K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 468.0
HKD2_k127_9970711_0 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 481.0
HKD2_k127_9970711_1 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000006705 113.0
HKD2_k127_997151_0 PFAM ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 351.0
HKD2_k127_997151_2 Heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000002622 136.0
HKD2_k127_997151_3 protein histidine kinase activity K14980 - 2.7.13.3 0.00000000000000000000001593 104.0
HKD2_k127_9985026_0 TIGRFAM competence protein ComEA helix-hairpin-helix repeat protein K02237 - - 0.0000000000000000000000000000000000000000008846 167.0