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Overview

ID MAG01797
Name HKD2_bin.42
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Actinomycetes
Order Actinomycetales
Family Micrococcaceae
Genus Arthrobacter
Species Arthrobacter sp030410515
Assembly information
Completeness (%) 58.84
Contamination (%) 0.07
GC content (%) 70.0
N50 (bp) 3,562
Genome size (bp) 2,061,308

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2310

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10048457_0 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 323.0
HKD2_k127_10048457_1 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001905 257.0
HKD2_k127_10049431_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.071e-264 820.0
HKD2_k127_10049431_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 434.0
HKD2_k127_10049431_2 DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 356.0
HKD2_k127_10049431_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000003039 190.0
HKD2_k127_10053548_0 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 414.0
HKD2_k127_10053548_1 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009056 276.0
HKD2_k127_10053548_2 Putative NAD(P)-binding K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000005511 249.0
HKD2_k127_10131825_0 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 516.0
HKD2_k127_10131825_1 Identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds - - - 0.00000000000000000000000000000000000000000000000000000000000000000007474 241.0
HKD2_k127_10131825_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.00000000000000000000000000000001925 126.0
HKD2_k127_10131825_4 pyridine nucleotide-disulfide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000005337 96.0
HKD2_k127_10136957_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 605.0
HKD2_k127_10136957_1 ISPsy14, transposition helper protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 300.0
HKD2_k127_10136957_2 peptidyl-tyrosine sulfation - - - 0.000004253 54.0
HKD2_k127_10152773_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 541.0
HKD2_k127_10152773_1 Belongs to the bacterial solute-binding protein 3 family K02030,K02424,K17073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 369.0
HKD2_k127_103155_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 5.107e-273 844.0
HKD2_k127_103155_1 Glycosyl transferases group 1 K16148 - 2.4.1.342 4.135e-245 759.0
HKD2_k127_103155_2 short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 589.0
HKD2_k127_103155_3 Acyl-CoA oxidase K00232 - 1.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000001616 237.0
HKD2_k127_1037654_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0008150,GO:0040007 6.1.1.6 4.112e-315 970.0
HKD2_k127_1037654_1 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 403.0
HKD2_k127_1037654_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000004807 104.0
HKD2_k127_1037654_3 - - - - 0.000000000000004581 81.0
HKD2_k127_1037654_4 Lsr2 - - - 0.000000000009711 65.0
HKD2_k127_104809_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0 1005.0
HKD2_k127_104809_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 8.204e-275 850.0
HKD2_k127_104809_2 homoserine dehydrogenase K00003,K12524 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 404.0
HKD2_k127_104809_3 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000001503 166.0
HKD2_k127_1059199_0 AI-2E family transporter K20469 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 595.0
HKD2_k127_1059199_1 PFAM Aldose 1-epimerase K01785 - 5.1.3.3 0.00000000000000000000000000000007185 124.0
HKD2_k127_1080980_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1489.0
HKD2_k127_1080980_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 295.0
HKD2_k127_1080980_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000007659 147.0
HKD2_k127_1127158_0 required for the transposition of insertion element IS2404 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 356.0
HKD2_k127_1127158_1 PFAM ADP-ribosylglycohydrolase - - - 0.0000000006523 62.0
HKD2_k127_1171246_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 2.311e-255 794.0
HKD2_k127_1171246_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 351.0
HKD2_k127_1171246_2 KR domain K00059 - 1.1.1.100 0.000000000000001497 77.0
HKD2_k127_119117_0 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 423.0
HKD2_k127_119117_1 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 397.0
HKD2_k127_119117_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 330.0
HKD2_k127_119117_3 - - - - 0.0006871 51.0
HKD2_k127_12254_0 GntP family permease K03299 - - 4.524e-264 819.0
HKD2_k127_12254_1 Fructose-bisphosphate aldolase class-II K01624,K08302 - 4.1.2.13,4.1.2.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 352.0
HKD2_k127_1295289_0 phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 531.0
HKD2_k127_1295289_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 403.0
HKD2_k127_1295289_2 Phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 364.0
HKD2_k127_1295289_3 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002109 287.0
HKD2_k127_1295289_4 Identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006855 245.0
HKD2_k127_1295289_5 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000003288 239.0
HKD2_k127_1295289_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000001954 146.0
HKD2_k127_1295289_7 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000001398 65.0
HKD2_k127_131454_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 488.0
HKD2_k127_131454_1 5-oxoprolinase (ATP-hydrolyzing) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 313.0
HKD2_k127_1326293_0 Melibiase K07407 - 3.2.1.22 0.0 1270.0
HKD2_k127_1326293_1 Beta-galactosidase - - - 0.0 1247.0
HKD2_k127_1326293_2 Bacterial extracellular solute-binding protein K02027 - - 6.058e-265 818.0
HKD2_k127_1326293_3 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 546.0
HKD2_k127_1326293_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 524.0
HKD2_k127_1326293_5 DeoR C terminal sensor domain K02444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 464.0
HKD2_k127_1326293_6 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 421.0
HKD2_k127_1326293_7 Protein of unknown function (DUF1524) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 407.0
HKD2_k127_1326293_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 334.0
HKD2_k127_1326293_9 pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 334.0
HKD2_k127_1330598_0 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 4.224e-209 656.0
HKD2_k127_1330598_1 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 316.0
HKD2_k127_1337337_0 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 373.0
HKD2_k127_1346223_0 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 453.0
HKD2_k127_1346223_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 434.0
HKD2_k127_1350538_0 ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 4.215e-295 923.0
HKD2_k127_1350538_1 Vitamin K epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 384.0
HKD2_k127_1350538_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000844 279.0
HKD2_k127_1350538_3 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000002762 257.0
HKD2_k127_1350538_4 Protein of unknown function (DUF4233) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006963 244.0
HKD2_k127_1357145_0 Integral membrane protein MviN K03980 GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0 1041.0
HKD2_k127_1357145_1 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 1.852e-286 883.0
HKD2_k127_1357145_2 serine threonine protein kinase - - - 2.303e-200 636.0
HKD2_k127_1357145_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 6.196e-199 623.0
HKD2_k127_1357145_4 Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 378.0
HKD2_k127_1357145_5 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 361.0
HKD2_k127_1357145_6 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000000000000000000000000000001512 218.0
HKD2_k127_1360845_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 516.0
HKD2_k127_1360845_1 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000001737 166.0
HKD2_k127_1360845_2 transcriptional regulator K05596 GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003700,GO:0005488,GO:0006275,GO:0006355,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000005226 60.0
HKD2_k127_1366204_0 PFAM CBS domain - - - 4.604e-243 755.0
HKD2_k127_1366204_1 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 608.0
HKD2_k127_1366204_2 ABC transporter K02074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 469.0
HKD2_k127_1366204_3 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 385.0
HKD2_k127_1368226_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1 0.0 1232.0
HKD2_k127_1368226_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 321.0
HKD2_k127_1382894_0 Transglutaminase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 461.0
HKD2_k127_1382894_1 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004287 243.0
HKD2_k127_1382894_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000001435 156.0
HKD2_k127_1384611_0 PFAM Amino acid K11738 - - 5.535e-295 910.0
HKD2_k127_1384611_1 Fumarase C C-terminus K01744 - 4.3.1.1 9.961e-281 868.0
HKD2_k127_1384611_2 Belongs to the AAA ATPase family - - - 9.039e-258 798.0
HKD2_k127_1384611_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 486.0
HKD2_k127_1384611_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00937,K01139 - 2.7.4.1,2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 312.0
HKD2_k127_1384611_5 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005562 274.0
HKD2_k127_1384611_6 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000000000000000000000000000000002466 237.0
HKD2_k127_1384611_7 L-asparaginase II - - - 0.00000000000000000000001186 101.0
HKD2_k127_1396373_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 344.0
HKD2_k127_1396373_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000001946 196.0
HKD2_k127_1396373_2 - - - - 0.000000000000000000000000000000008493 133.0
HKD2_k127_1401730_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 611.0
HKD2_k127_1401730_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 385.0
HKD2_k127_1417263_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 443.0
HKD2_k127_1417263_1 - - - - 0.00000000000000000000000000000000000000000000002741 172.0
HKD2_k127_1417263_2 Helix-turn-helix domain protein - - - 0.000000000005436 67.0
HKD2_k127_1419147_0 spermidine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 453.0
HKD2_k127_1419147_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000006024 166.0
HKD2_k127_1419147_2 aminotransferase class I and II K00812,K14260,K14267 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.6.1.1,2.6.1.17,2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000002931 152.0
HKD2_k127_1422059_0 PFAM aldo keto reductase K06221 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.346 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 527.0
HKD2_k127_1422059_1 regulation of cellular protein catabolic process - GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 304.0
HKD2_k127_1422059_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000007441 238.0
HKD2_k127_1422059_3 Carbon starvation protein CstA K06200 - - 0.00000000000000000000000000000000000000002997 153.0
HKD2_k127_1422059_4 Selenoprotein, putative - - - 0.000000000000000000000000000343 119.0
HKD2_k127_1422059_6 - - - - 0.00008661 46.0
HKD2_k127_1424860_0 Peptidase M50B-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 325.0
HKD2_k127_1424860_1 zinc ion binding K06204 - - 0.0000000000000000000000000000000000000000000000009819 185.0
HKD2_k127_1424860_2 conserved protein (DUF2249) - - - 0.000000000000000000000000000000000000000000003543 169.0
HKD2_k127_1438510_0 WYL domain K13572,K13573 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 7.619e-201 633.0
HKD2_k127_1438510_1 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 500.0
HKD2_k127_1438510_2 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 415.0
HKD2_k127_1438510_3 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003081 266.0
HKD2_k127_144018_0 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase K01236 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016787,GO:0016798,GO:0030978,GO:0030980,GO:0033942,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0071704,GO:1901575,GO:1901576 3.2.1.141 0.0 1058.0
HKD2_k127_144018_1 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 8.698e-226 700.0
HKD2_k127_144018_2 aldo keto reductase K19265 - - 1.838e-206 644.0
HKD2_k127_144018_3 synthase K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 5.4.99.15 2.093e-206 647.0
HKD2_k127_144018_4 Protein conserved in bacteria - - - 0.0000000000000000000000000000000001223 133.0
HKD2_k127_1440491_0 Phenol hydroxylase, C-terminal dimerisation domain K03380 - 1.14.13.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 374.0
HKD2_k127_1440491_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 341.0
HKD2_k127_1463598_0 Diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 510.0
HKD2_k127_1463598_1 Fusaric acid resistance protein-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 498.0
HKD2_k127_1463598_2 transcriptional regulator K02624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 419.0
HKD2_k127_1463598_3 CoA-transferase K01029,K01032 GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482 2.8.3.5,2.8.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 410.0
HKD2_k127_1463598_4 CoA-transferase K01031 - 2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 373.0
HKD2_k127_1463598_5 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000000000000001904 241.0
HKD2_k127_1463598_8 helix_turn_helix isocitrate lyase regulation - - - 0.0001651 44.0
HKD2_k127_1470487_0 DNA-binding transcription factor activity - - - 1.651e-290 911.0
HKD2_k127_1470487_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 384.0
HKD2_k127_1470487_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000002884 213.0
HKD2_k127_1470487_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000003164 217.0
HKD2_k127_1470487_4 TniQ - - - 0.000000000000000000000000000000001295 147.0
HKD2_k127_1470487_5 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000001578 115.0
HKD2_k127_1470487_6 TniQ - - - 0.00000000000000000000000005762 119.0
HKD2_k127_1470487_7 Integrase catalytic - - - 0.00000000000000000001614 93.0
HKD2_k127_1490228_0 PFAM Transposase, IS204 IS1001 IS1096 IS1165 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 341.0
HKD2_k127_1490228_1 TAP-like protein - - - 0.00000000000000000000000000000006293 131.0
HKD2_k127_1490228_2 RNA-directed DNA polymerase (reverse transcriptase) K00986 - 2.7.7.49 0.0000000000000001391 80.0
HKD2_k127_1536124_0 cell division ATP-binding protein K09812 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 466.0
HKD2_k127_1536124_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005579 255.0
HKD2_k127_1536124_2 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.000000000000000000009119 92.0
HKD2_k127_1559863_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 4.55e-238 739.0
HKD2_k127_1559863_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 577.0
HKD2_k127_1560956_0 transposase activity - - - 3.188e-223 699.0
HKD2_k127_1582981_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 6.135e-254 788.0
HKD2_k127_1582981_1 Isochorismatase family K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 362.0
HKD2_k127_1582981_2 Domain of unknown function (DUF2017) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 323.0
HKD2_k127_1582981_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000000005125 180.0
HKD2_k127_1582981_5 Type III restriction enzyme, res subunit - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000003339 119.0
HKD2_k127_1596691_0 Histidine kinase K02484 - 2.7.13.3 1.935e-237 746.0
HKD2_k127_1596691_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 490.0
HKD2_k127_1596691_2 response regulator K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 310.0
HKD2_k127_1596691_3 Belongs to the WXG100 family - - - 0.00000000000000000000000000000000000002589 149.0
HKD2_k127_1596691_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679 - 0.000000000007704 64.0
HKD2_k127_1604331_0 PFAM MULE transposase, conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 410.0
HKD2_k127_1604331_1 - - - - 0.0000000000000000000000000000000000000000000000006159 187.0
HKD2_k127_1604331_2 Transposase - - - 0.00000000000006365 80.0
HKD2_k127_162362_0 probably involved in cell wall - - - 0.0 1180.0
HKD2_k127_162362_1 phospholipase C K01114 - 3.1.4.3 1.734e-306 957.0
HKD2_k127_162362_10 Uncharacterised protein family (UPF0014) K02069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 291.0
HKD2_k127_162362_11 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001655 276.0
HKD2_k127_162362_12 Asp23 family, cell envelope-related function - - - 0.000000000000000000000000000000000000000000000000000000000000000000007125 237.0
HKD2_k127_162362_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000566 234.0
HKD2_k127_162362_14 - - - - 0.00000000000000000000000000000000000000000000000000000000001016 213.0
HKD2_k127_162362_15 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000001252 164.0
HKD2_k127_162362_17 Protein of unknown function (DUF2945) - - - 0.0000000000000000000000000000002695 124.0
HKD2_k127_162362_18 CsbD-like - - - 0.000000000000000000000000007338 111.0
HKD2_k127_162362_2 - - - - 8.006e-266 834.0
HKD2_k127_162362_21 - - - - 0.000000000000000000000005053 102.0
HKD2_k127_162362_3 chitin binding K01183 - 3.2.1.14 2.159e-212 672.0
HKD2_k127_162362_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 604.0
HKD2_k127_162362_5 Sugar (and other) transporter K03762 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 498.0
HKD2_k127_162362_6 cyclic-guanylate-specific phosphodiesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 409.0
HKD2_k127_162362_7 hydrolase activity, acting on ester bonds K19707 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 392.0
HKD2_k127_162362_8 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 316.0
HKD2_k127_162362_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 303.0
HKD2_k127_1633522_0 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 555.0
HKD2_k127_1633522_1 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 327.0
HKD2_k127_1633522_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 300.0
HKD2_k127_1633522_3 Mo-molybdopterin cofactor metabolic process K03636,K21142 - 2.8.1.12 0.00000000000000000000000000000000000001199 145.0
HKD2_k127_1633522_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000706 91.0
HKD2_k127_1646533_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 454.0
HKD2_k127_1646533_1 Transposase and inactivated derivatives - - - 0.000000000000005737 79.0
HKD2_k127_1646533_2 PFAM Transposase DDE domain - - - 0.00000001195 56.0
HKD2_k127_1665874_0 drug resistance transporter, Bcr CflA subfamily K07552 - - 3.044e-219 688.0
HKD2_k127_1665874_1 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 355.0
HKD2_k127_1665874_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 294.0
HKD2_k127_1682113_0 Domain of unknown function (DUF5129) - - - 2.71e-202 647.0
HKD2_k127_1682113_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 445.0
HKD2_k127_1682113_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 291.0
HKD2_k127_1682113_3 cysteine-type peptidase activity K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 289.0
HKD2_k127_1682113_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000001081 197.0
HKD2_k127_1682113_5 - - - - 0.0000000000000000000000000000000000000127 155.0
HKD2_k127_1692815_0 Major facilitator superfamily K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 436.0
HKD2_k127_1692815_1 Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05565,K14086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 424.0
HKD2_k127_1696568_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 8.828e-221 686.0
HKD2_k127_1696568_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 537.0
HKD2_k127_1696568_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000009319 131.0
HKD2_k127_1696568_3 homoserine dehydrogenase K00003,K12524 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 0.000000000000000000002285 94.0
HKD2_k127_171060_0 Subtilase family - - - 0.0 1171.0
HKD2_k127_171060_1 Histidine Phosphotransfer domain - - - 6.744e-263 844.0
HKD2_k127_171060_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 409.0
HKD2_k127_171060_3 Small secreted domain (DUF320) - - - 0.0000000000000000000000000000000000000000000000004725 181.0
HKD2_k127_171060_6 Belongs to the UPF0337 (CsbD) family - - - 0.000000002291 59.0
HKD2_k127_1726908_0 Required for chromosome condensation and partitioning K03529 - - 5.536e-212 677.0
HKD2_k127_1726908_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648,K22317 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 305.0
HKD2_k127_175730_0 Sodium hydrogen exchanger - - - 1.305e-228 715.0
HKD2_k127_175730_1 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide K01479 - 3.5.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 439.0
HKD2_k127_1763055_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.118e-248 770.0
HKD2_k127_1763055_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K11608 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005488,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0019637,GO:0019693,GO:0019752,GO:0030497,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033818,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035336,GO:0035337,GO:0035383,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901567,GO:1901568,GO:1901576,GO:1901681 2.3.1.180 8.01e-198 619.0
HKD2_k127_1763055_2 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 391.0
HKD2_k127_1763055_3 Acyl transferase domain K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000001051 240.0
HKD2_k127_1763055_4 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000009719 166.0
HKD2_k127_1763055_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000002372 152.0
HKD2_k127_1800934_0 Bifunctional purine biosynthesis protein PurH K00602 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 441.0
HKD2_k127_1800934_1 Bifunctional purine biosynthesis protein PurH K00602 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 437.0
HKD2_k127_1805395_0 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 541.0
HKD2_k127_1805395_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 302.0
HKD2_k127_1805395_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000002874 218.0
HKD2_k127_1821528_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1215.0
HKD2_k127_1821528_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 4.177e-251 781.0
HKD2_k127_1821528_2 Belongs to the globin family K05916 - 1.14.12.17 1.766e-228 711.0
HKD2_k127_1821528_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 299.0
HKD2_k127_1821528_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001577 254.0
HKD2_k127_1821528_5 transcriptional regulator K13771 - - 0.00000000000000000000000000000000000000000000000000000000000000000001236 240.0
HKD2_k127_1826523_0 PFAM Uncharacterised protein family (UPF0236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 364.0
HKD2_k127_1826665_0 AMP-binding enzyme K00666 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.0 1020.0
HKD2_k127_1826665_1 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 542.0
HKD2_k127_1826665_2 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 341.0
HKD2_k127_1826665_3 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 314.0
HKD2_k127_1826665_4 Belongs to the thioredoxin family K00384,K03671 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000003166 259.0
HKD2_k127_1826665_5 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000004097 169.0
HKD2_k127_1826665_6 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000002695 93.0
HKD2_k127_1833054_0 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 601.0
HKD2_k127_1833054_1 Uncharacterized protein family UPF0029 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 354.0
HKD2_k127_1833054_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 0.0000000000000000000000000000000000000004362 149.0
HKD2_k127_1833054_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000002139 93.0
HKD2_k127_1866392_0 Histidine kinase K07768 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 1.283e-217 679.0
HKD2_k127_1866392_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 503.0
HKD2_k127_1866392_2 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0016020,GO:0019220,GO:0019222,GO:0022611,GO:0031323,GO:0031324,GO:0032502,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042221,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044444,GO:0044464,GO:0045936,GO:0046677,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:0071944,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 376.0
HKD2_k127_1866392_3 protein-(glutamine-N5) methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000663 247.0
HKD2_k127_1866392_4 Transcriptional regulatory protein, C terminal K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000004173 110.0
HKD2_k127_1869587_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 2.681e-235 731.0
HKD2_k127_1869587_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 356.0
HKD2_k127_1870124_0 heat shock protein binding - - - 0.0009521 49.0
HKD2_k127_187533_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0 1020.0
HKD2_k127_187533_1 Superfamily I DNA and RNA helicases and helicase subunits - - - 1.774e-288 893.0
HKD2_k127_187533_2 Domain of unknown function (DUF3817) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 305.0
HKD2_k127_187533_3 SURF1 family - - - 0.000000000000000000000002618 103.0
HKD2_k127_1888502_0 PFAM sodium calcium exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 499.0
HKD2_k127_1888502_1 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD K16013,K16014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 300.0
HKD2_k127_189646_0 cell envelope-related transcriptional attenuator - - - 2.873e-256 807.0
HKD2_k127_189646_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.3.4.18 8.946e-210 668.0
HKD2_k127_189646_2 mannose-6-phosphate isomerase, class I K01809 - 5.3.1.8 1.052e-195 617.0
HKD2_k127_189646_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 543.0
HKD2_k127_189646_4 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 435.0
HKD2_k127_189646_5 GtrA-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 312.0
HKD2_k127_189646_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0008150,GO:0040007 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 307.0
HKD2_k127_189646_7 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - - 0.00000000000000000000000000000000000000000000000000129 187.0
HKD2_k127_19188_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 534.0
HKD2_k127_19188_1 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000000000000000000000000003843 221.0
HKD2_k127_19188_2 branched-chain amino acid - - - 0.000000000000000000000000000006561 119.0
HKD2_k127_19188_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000003953 94.0
HKD2_k127_1923914_0 Bacterial periplasmic substrate-binding proteins K02424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 471.0
HKD2_k127_1923914_1 phage tail protein - - - 0.000000000000000000000000000000000000000000000000000000000000002408 222.0
HKD2_k127_1923914_2 Binding-protein-dependent transport system inner membrane component K02029,K02030,K02424,K10009 - - 0.00000000000000000000000000000000000000003921 153.0
HKD2_k127_1933950_0 UvrD-like helicase C-terminal domain K03657 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 0.0 1044.0
HKD2_k127_1933950_1 Belongs to the Nudix hydrolase family K03426 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 379.0
HKD2_k127_1944733_0 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 543.0
HKD2_k127_1944733_1 ABC transporter permease K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 466.0
HKD2_k127_194798_0 Circularly permuted ATP-grasp type 2 - - - 0.0 1008.0
HKD2_k127_194798_1 ERAP1-like C-terminal domain K01256,K08776 - 3.4.11.2 2.041e-284 876.0
HKD2_k127_194798_2 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 605.0
HKD2_k127_194798_3 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 461.0
HKD2_k127_1952636_0 Major facilitator superfamily - - - 4.511e-217 681.0
HKD2_k127_1952636_1 SseB protein N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 434.0
HKD2_k127_1952636_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814,K01817 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 332.0
HKD2_k127_1982959_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 483.0
HKD2_k127_1982959_1 Tryptophan halogenase K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 445.0
HKD2_k127_1982959_2 Isochorismate synthase K02552 - 5.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 304.0
HKD2_k127_2069601_0 Restriction endonuclease K07448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 388.0
HKD2_k127_2069601_1 - - - - 0.0000000000000000001495 93.0
HKD2_k127_2069601_2 required for the transposition of insertion element IS2404 - - - 0.00005036 45.0
HKD2_k127_2099634_0 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 4.354e-222 694.0
HKD2_k127_2099634_1 Glycosyl hydrolase family 76 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 595.0
HKD2_k127_2099634_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 451.0
HKD2_k127_2120201_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 0.0 1125.0
HKD2_k127_2120201_1 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 389.0
HKD2_k127_2120201_2 tyrosine recombinase K04763 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000004697 211.0
HKD2_k127_2120201_3 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000003047 140.0
HKD2_k127_2125547_0 Domain of unknown function (DUF4032) - - - 1.493e-247 766.0
HKD2_k127_2125547_1 ABC transporter K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001476 265.0
HKD2_k127_2155732_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000001452 242.0
HKD2_k127_2155732_1 UPF0060 membrane protein K09771 - - 0.0000000000000000000000000000000000000000000000000000000000295 214.0
HKD2_k127_2158958_0 DEAD DEAH box helicase - - - 0.0 1546.0
HKD2_k127_2158958_1 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 538.0
HKD2_k127_2158958_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 295.0
HKD2_k127_2215997_0 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005799 251.0
HKD2_k127_2215997_1 Lsr2 - - - 0.00000000000000000000000001264 114.0
HKD2_k127_2215997_2 Acid phosphatase homologues K06153,K19302 - 3.6.1.27 0.0001491 49.0
HKD2_k127_2220918_0 phosphatase K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 424.0
HKD2_k127_2220918_1 ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 299.0
HKD2_k127_2220918_2 (FHA) domain - - - 0.00000000000000000000000000000000000000000001236 179.0
HKD2_k127_2291533_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 7.502e-210 653.0
HKD2_k127_2291533_1 LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 542.0
HKD2_k127_229167_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 547.0
HKD2_k127_229167_1 Belongs to the peptidase S1B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003034 252.0
HKD2_k127_2294567_0 Major Facilitator Superfamily K19577 - - 1.558e-210 657.0
HKD2_k127_2294567_1 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000003022 216.0
HKD2_k127_2307585_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 6.189e-229 711.0
HKD2_k127_2307585_1 Phosphate starvation-inducible protein PhoH K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 6.342e-215 671.0
HKD2_k127_2307585_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 598.0
HKD2_k127_2307585_3 Protein of unknown function (DUF3097) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 529.0
HKD2_k127_2307585_4 Sporulation and spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 458.0
HKD2_k127_2307585_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 410.0
HKD2_k127_2307585_6 Transporter associated domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 340.0
HKD2_k127_2307585_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 302.0
HKD2_k127_2307585_8 Domain of unknown function (DUF4870) K09940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006661 266.0
HKD2_k127_2307585_9 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000006909 142.0
HKD2_k127_2394442_0 Major Facilitator Superfamily - - - 1.279e-266 824.0
HKD2_k127_2394442_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 5.883e-212 662.0
HKD2_k127_2394442_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 404.0
HKD2_k127_2394442_3 PspC domain - - - 0.000000000000000000000000000000000000000000000000000000007312 201.0
HKD2_k127_2394442_4 PspC domain - - - 0.000000000000000000000000000000000000007025 145.0
HKD2_k127_2394442_5 - - - - 0.00000000000000000000000003875 109.0
HKD2_k127_241449_0 Displays ATPase and GTPase activities K06958 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 560.0
HKD2_k127_241449_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 335.0
HKD2_k127_241449_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 325.0
HKD2_k127_2435202_0 Vitamin K-dependent gamma-carboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 302.0
HKD2_k127_2435202_2 - - - - 0.0000000000000000000000000001193 125.0
HKD2_k127_24385_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009699 555.0
HKD2_k127_24385_1 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000000000000000000000105 230.0
HKD2_k127_24385_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000009934 131.0
HKD2_k127_243911_0 Aldehyde dehydrogenase family K00146,K11947 - 1.2.1.39 3.565e-240 758.0
HKD2_k127_243911_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 379.0
HKD2_k127_243911_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 293.0
HKD2_k127_2440450_0 Phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 2.861e-226 719.0
HKD2_k127_2440450_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 381.0
HKD2_k127_2440450_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000002405 197.0
HKD2_k127_2440450_3 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000000000000000004897 175.0
HKD2_k127_2460153_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1162.0
HKD2_k127_2460153_1 MgsA AAA+ ATPase C terminal K07478 - - 7.171e-250 773.0
HKD2_k127_2460153_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 397.0
HKD2_k127_2460153_3 Bacterial protein of unknown function (DUF948) - - - 0.00000000000000000000000000000000000000000000000000000000062 203.0
HKD2_k127_2460153_4 - - - - 0.0000000000000000000000000000001326 125.0
HKD2_k127_2474752_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204 1.2.4.1 0.0 1797.0
HKD2_k127_2474752_1 PucR C-terminal helix-turn-helix domain - GO:0008150,GO:0040007 - 1.481e-238 741.0
HKD2_k127_2474752_2 Acyl transferase domain K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 461.0
HKD2_k127_2474752_3 Redoxin K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000169 275.0
HKD2_k127_2474752_4 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001294 269.0
HKD2_k127_2474752_5 Protein of unknown function (DUF3052) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001041 255.0
HKD2_k127_2531125_0 ABC-type Fe3 transport system permease component K02011 - - 2.92e-213 667.0
HKD2_k127_2531125_1 COG1840 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 587.0
HKD2_k127_2560486_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 1.197e-195 611.0
HKD2_k127_2560486_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 567.0
HKD2_k127_2560486_2 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 436.0
HKD2_k127_2567057_0 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 374.0
HKD2_k127_2567057_1 cytochrome c biogenesis protein K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 352.0
HKD2_k127_2567057_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 344.0
HKD2_k127_2567057_3 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 340.0
HKD2_k127_2567057_4 ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006443 283.0
HKD2_k127_2567057_5 - - - - 0.0000000000000000000000000000000000000000000000000003049 193.0
HKD2_k127_2569382_0 Major facilitator superfamily - - - 2.03e-322 990.0
HKD2_k127_2569382_1 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K08139 - - 2.485e-278 859.0
HKD2_k127_2569382_2 Major Facilitator Superfamily K08221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 460.0
HKD2_k127_2569382_3 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005646 268.0
HKD2_k127_2569382_4 Major Facilitator - - - 0.000000000000000000000007231 111.0
HKD2_k127_2575296_0 Histidine kinase - - - 2.107e-248 778.0
HKD2_k127_2575296_1 Bacterial transglutaminase-like N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 563.0
HKD2_k127_2575296_2 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 462.0
HKD2_k127_2575296_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 379.0
HKD2_k127_2575296_4 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 325.0
HKD2_k127_2575473_0 Domain of Unknown Function (DUF349) - - - 6.164e-226 707.0
HKD2_k127_2575473_1 Histidine--tRNA ligase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 454.0
HKD2_k127_2575473_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 433.0
HKD2_k127_2583131_0 Belongs to the aldehyde dehydrogenase family K13821 - 1.2.1.88,1.5.5.2 4.128e-217 678.0
HKD2_k127_2584929_0 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 463.0
HKD2_k127_2584929_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 306.0
HKD2_k127_2585395_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 512.0
HKD2_k127_2585395_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 370.0
HKD2_k127_2585395_2 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000206 164.0
HKD2_k127_2586468_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 1.429e-298 922.0
HKD2_k127_2586468_1 Rieske-like [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000583 276.0
HKD2_k127_2602156_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 477.0
HKD2_k127_2602156_1 Amino-transferase class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 395.0
HKD2_k127_2626550_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.309e-214 673.0
HKD2_k127_2626550_1 NmrA-like family K19267 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 402.0
HKD2_k127_2626550_2 Pfam NUDIX - - - 0.000000000000000000000000000000000000000000000000000000000000001399 227.0
HKD2_k127_2626550_3 acetyltransferase K20791 - 2.3.1.255 0.00000000000000000000000726 110.0
HKD2_k127_2632769_0 Domain of unknown function (DUF4118) K07646 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 2.7.13.3 8.979e-272 846.0
HKD2_k127_2632769_1 Two component transcriptional regulator, winged helix family K02483,K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 382.0
HKD2_k127_2632769_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003121 236.0
HKD2_k127_2632769_3 Identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds - - - 0.00000000000000000000000000000000000004199 152.0
HKD2_k127_2640500_0 Penicillin binding protein transpeptidase domain K05364 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 1.492e-277 857.0
HKD2_k127_2640500_1 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 582.0
HKD2_k127_26435_0 Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.1.1.16,6.3.1.13 6.207e-224 697.0
HKD2_k127_26435_1 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 560.0
HKD2_k127_26435_2 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 384.0
HKD2_k127_26435_3 Belongs to the peptidase M50B family - - - 0.00000005617 56.0
HKD2_k127_2652915_0 synthetase K01895 - 6.2.1.1 0.0 1084.0
HKD2_k127_2652915_1 acyl-CoA dehydrogenase K00252 - 1.3.8.6 3.63e-222 694.0
HKD2_k127_2652915_2 diguanylate cyclase - - - 6.352e-201 633.0
HKD2_k127_2652915_3 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 541.0
HKD2_k127_2652915_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 298.0
HKD2_k127_2652915_5 transcriptional regulator K21685 - - 0.000000000000000000000000000000000000000000000000000000000000000003221 236.0
HKD2_k127_2652915_6 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000003545 86.0
HKD2_k127_2652995_0 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 509.0
HKD2_k127_2652995_1 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 427.0
HKD2_k127_2652995_2 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 299.0
HKD2_k127_2652995_3 ABC-type nitrate sulfonate bicarbonate transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 308.0
HKD2_k127_2653016_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 572.0
HKD2_k127_2653016_1 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 316.0
HKD2_k127_2670559_0 Major facilitator superfamily - - - 9.877e-209 656.0
HKD2_k127_2670559_1 Mediates influx of magnesium ions K03284 - - 1.957e-195 613.0
HKD2_k127_2670559_2 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 308.0
HKD2_k127_2670559_3 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 304.0
HKD2_k127_2670559_4 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000004019 287.0
HKD2_k127_2670559_5 ABC1 family K03688 - - 0.00000000000000002398 86.0
HKD2_k127_2677693_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 1.18e-196 634.0
HKD2_k127_2677693_1 ABC transporter substrate-binding protein K02051,K15553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 460.0
HKD2_k127_2677693_2 Binding-protein-dependent transport system inner membrane component K15554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 404.0
HKD2_k127_2677693_3 ATPases associated with a variety of cellular activities K15555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 374.0
HKD2_k127_2677693_4 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000001753 198.0
HKD2_k127_2679843_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 596.0
HKD2_k127_2679843_1 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002654 238.0
HKD2_k127_2689222_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 4.63e-242 748.0
HKD2_k127_2689222_1 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002418 269.0
HKD2_k127_2711846_0 Secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 591.0
HKD2_k127_2711846_1 bacterial-type flagellum organization - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 455.0
HKD2_k127_2711846_2 Type ii secretion system K12510 - - 0.000000000000000000000000000000000000000000000000000005381 201.0
HKD2_k127_2712444_0 Rieske [2Fe-2S] domain K03890 - - 4.118e-202 631.0
HKD2_k127_2712444_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 571.0
HKD2_k127_2712444_2 Cytochrome c K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 475.0
HKD2_k127_2712444_3 cytochrome c oxidase, subunit III K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 441.0
HKD2_k127_2712444_4 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 349.0
HKD2_k127_2712444_5 isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001847 286.0
HKD2_k127_2712444_6 Protein of unknown function (DUF3054) - - - 0.000000000000000000000000000000000000000000000000000006068 192.0
HKD2_k127_2712444_7 AsnC family - - - 0.000000000000000000000000000000000000000000000000092 179.0
HKD2_k127_2712444_8 Transcriptional regulator - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0010045,GO:0032025,GO:0042221,GO:0050896,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000985 180.0
HKD2_k127_2712444_9 tautomerase - - - 0.000000000000000000000000000000000000000000000008179 175.0
HKD2_k127_2730704_0 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 7.018e-309 953.0
HKD2_k127_2730704_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 433.0
HKD2_k127_2730704_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 0.000000003358 58.0
HKD2_k127_2734690_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0 1011.0
HKD2_k127_2734690_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 571.0
HKD2_k127_2734690_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 489.0
HKD2_k127_2734690_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 447.0
HKD2_k127_2734690_4 Preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000000000000000000000000000000000000002546 217.0
HKD2_k127_2740254_0 PFAM Extracellular ligand-binding receptor K01999 - - 2.243e-252 784.0
HKD2_k127_2740254_1 ACT domain K09964 - - 0.00000000000000000000000000000000000000000000000000000000000000000003625 233.0
HKD2_k127_2748055_0 haloacid dehalogenase-like hydrolase - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 477.0
HKD2_k127_2748055_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 387.0
HKD2_k127_2748055_2 Glutaredoxin-like domain (DUF836) - - - 0.000000000000000000000000000000001013 131.0
HKD2_k127_2782371_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 8.454e-292 900.0
HKD2_k127_2782371_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 1.359e-230 717.0
HKD2_k127_2782371_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 1.099e-219 687.0
HKD2_k127_2782371_3 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 564.0
HKD2_k127_2782371_4 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000000000000000000000345 179.0
HKD2_k127_2782371_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000002573 66.0
HKD2_k127_2790878_0 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 505.0
HKD2_k127_2790878_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 461.0
HKD2_k127_2790878_2 Transglycosylase associated protein - - - 0.00000000000000000000000000000000000000000000002397 171.0
HKD2_k127_2790878_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000000008771 152.0
HKD2_k127_2790878_4 Major Facilitator Superfamily K19577 - - 0.00000000000000000000000000001679 117.0
HKD2_k127_2795544_0 DNA polymerase K02337 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 0.0 1013.0
HKD2_k127_2795544_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000006797 168.0
HKD2_k127_28081_0 PFAM AMP-dependent synthetase and ligase - - - 2.915e-275 855.0
HKD2_k127_28081_1 aminotransferase class I and II K05825 - - 1.028e-253 785.0
HKD2_k127_28081_2 Binding-protein-dependent transport system inner membrane component K02033 - - 6.446e-203 632.0
HKD2_k127_28081_3 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 542.0
HKD2_k127_28081_4 NAD(P)H-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 321.0
HKD2_k127_28081_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 297.0
HKD2_k127_28081_6 universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001548 229.0
HKD2_k127_28081_8 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000008031 142.0
HKD2_k127_2810250_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 4.607e-269 829.0
HKD2_k127_2810250_1 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000009442 136.0
HKD2_k127_2818518_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 594.0
HKD2_k127_2834829_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001548 265.0
HKD2_k127_2834829_1 Homeodomain-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000003091 216.0
HKD2_k127_2834829_2 DDE_Tnp_1-associated - - - 0.000000000000000000000000000007048 128.0
HKD2_k127_2834829_3 Transposase DDE domain - - - 0.00000000000000001178 86.0
HKD2_k127_2834829_4 - - - - 0.000000000002901 79.0
HKD2_k127_2878459_0 Major Facilitator Superfamily - - - 1.224e-282 871.0
HKD2_k127_2878459_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000005858 162.0
HKD2_k127_2882768_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 353.0
HKD2_k127_2882768_4 - - - - 0.000000003523 57.0
HKD2_k127_2882877_0 Belongs to the phosphoglycerate mutase family - GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009628,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036293,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 329.0
HKD2_k127_2882877_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000002899 200.0
HKD2_k127_2882877_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000003541 137.0
HKD2_k127_2884952_0 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 346.0
HKD2_k127_2884952_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001278 267.0
HKD2_k127_2884952_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000000008441 201.0
HKD2_k127_2884952_3 - - - - 0.000000000000000000000000000000005322 128.0
HKD2_k127_2884952_4 - - - - 0.00000000000000000000007202 98.0
HKD2_k127_2891169_0 Succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 7.522e-207 652.0
HKD2_k127_2891169_1 integral membrane protein - - - 1.254e-202 639.0
HKD2_k127_2891169_10 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 294.0
HKD2_k127_2891169_11 ABC transporter K10007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 287.0
HKD2_k127_2891169_12 regulation of cell shape - - - 0.0000000000000000000000000000000002621 136.0
HKD2_k127_2891169_13 Protein of unknown function (DUF3117) - - - 0.000000000000000000000000000000001499 130.0
HKD2_k127_2891169_2 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 584.0
HKD2_k127_2891169_3 Bacterial periplasmic substrate-binding proteins K10005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 509.0
HKD2_k127_2891169_4 ABC transporter K10007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 469.0
HKD2_k127_2891169_5 ABC transporter, ATP-binding protein K10008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 466.0
HKD2_k127_2891169_6 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 466.0
HKD2_k127_2891169_7 O-methyltransferase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 397.0
HKD2_k127_2891169_8 heme binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 374.0
HKD2_k127_2891169_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 326.0
HKD2_k127_2901917_0 PFAM sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 463.0
HKD2_k127_2901917_1 PFAM Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000127 162.0
HKD2_k127_2901917_2 Transposase DDE domain - - - 0.000000000000000000000000000000000009222 137.0
HKD2_k127_2901917_3 PFAM Integrase core domain K07497 - - 0.00002536 53.0
HKD2_k127_2910697_0 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 426.0
HKD2_k127_2910697_1 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 368.0
HKD2_k127_2919785_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1412.0
HKD2_k127_2919785_1 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 7.766e-303 938.0
HKD2_k127_2919785_2 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 394.0
HKD2_k127_2919785_3 Gcn5-related n-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006462 263.0
HKD2_k127_2919948_0 PFAM 60 kDa inner membrane insertion protein K03217 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 560.0
HKD2_k127_2919948_1 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 384.0
HKD2_k127_2919948_2 Putative single-stranded nucleic acids-binding domain K06346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001035 276.0
HKD2_k127_2919948_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000000000000000000000000000000000000000849 224.0
HKD2_k127_2919948_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0008150,GO:0040007 3.1.26.5 0.00000000000000000000000000000000000000000000000000000000104 203.0
HKD2_k127_2919948_5 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.00000000000000000000000000000000000000005865 154.0
HKD2_k127_2919948_6 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000003844 84.0
HKD2_k127_2929835_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 1.733e-283 874.0
HKD2_k127_2929835_1 synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 435.0
HKD2_k127_2929835_2 Amino-transferase class IV K02619 - 4.1.3.38 0.000000000000000000003518 93.0
HKD2_k127_2933082_0 Penicillin-binding Protein dimerisation domain K01286 - 3.4.16.4 2.669e-245 767.0
HKD2_k127_2959284_0 LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 524.0
HKD2_k127_2959284_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005654 270.0
HKD2_k127_2959284_2 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000001428 199.0
HKD2_k127_2959284_3 amino acid K03294 - - 0.00000000006531 63.0
HKD2_k127_2960518_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 385.0
HKD2_k127_2960518_1 YCII-related domain - - - 0.000000000000000000000000000000000000005109 147.0
HKD2_k127_2960518_2 Major Facilitator Superfamily - - - 0.000000000000002431 76.0
HKD2_k127_2963833_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0008094,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0042623,GO:0061505,GO:0140097 5.99.1.3 1.67e-311 958.0
HKD2_k127_2963833_1 Transmembrane domain of unknown function (DUF3566) - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 294.0
HKD2_k127_2990711_0 Extracellular solute-binding protein K02027 - - 7.693e-230 718.0
HKD2_k127_2990711_1 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 533.0
HKD2_k127_2990711_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 497.0
HKD2_k127_2990711_3 PFAM regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 346.0
HKD2_k127_2997853_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 582.0
HKD2_k127_2997853_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 567.0
HKD2_k127_2998636_0 FOG Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002189 273.0
HKD2_k127_2998636_1 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000009043 207.0
HKD2_k127_2998636_2 Transposase - - - 0.0000000000000000000000000000000000000000000000000000001103 201.0
HKD2_k127_2998636_3 Winged helix-turn helix K07499 - - 0.00000000006757 65.0
HKD2_k127_3008968_0 TIGRFAM formaldehyde dehydrogenase, glutathione-independent K00148 - 1.2.1.46 6.263e-260 803.0
HKD2_k127_3008968_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006198,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0008199,GO:0008663,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009187,GO:0009214,GO:0009259,GO:0009261,GO:0009405,GO:0009987,GO:0016043,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042301,GO:0042545,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0045229,GO:0046058,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051704,GO:0055086,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.4.53 0.0000000000000000000000000000000000000000000000008976 177.0
HKD2_k127_3015093_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 377.0
HKD2_k127_3015093_1 Transposase K00957,K07497 - 2.7.7.4 0.00000000000001206 86.0
HKD2_k127_3017707_0 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 298.0
HKD2_k127_3017707_1 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 310.0
HKD2_k127_3017707_2 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000003501 217.0
HKD2_k127_3017707_3 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000001608 175.0
HKD2_k127_3017707_4 DDE superfamily endonuclease - - - 0.00000000000000000004335 96.0
HKD2_k127_3068672_0 HELICc2 K03722 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.4.12 5e-324 994.0
HKD2_k127_3068672_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 2.087e-214 668.0
HKD2_k127_3068672_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 461.0
HKD2_k127_3068672_3 Lysin motif - - - 0.00000000000000000000000000000000000000002926 158.0
HKD2_k127_3068672_4 imidazoleglycerol-phosphate dehydratase K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.0000000000000000000007516 96.0
HKD2_k127_3072435_0 Ammonium Transporter K03320 - - 8.722e-229 715.0
HKD2_k127_3072435_1 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 572.0
HKD2_k127_3072435_2 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 348.0
HKD2_k127_3072435_3 Na H antiporter K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000165 231.0
HKD2_k127_3072435_4 transposase activity K07483 - - 0.000000000000000000000000000000000003519 143.0
HKD2_k127_3074523_0 - - - - 0.00000000000000000000000000000000000000000000000000000000004373 213.0
HKD2_k127_3074523_1 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000004001 141.0
HKD2_k127_3074523_2 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000001414 115.0
HKD2_k127_3074523_3 - - - - 0.0000000000000000000000159 102.0
HKD2_k127_3085688_0 Beta-Casp domain K07576 - - 8.12e-255 791.0
HKD2_k127_3085688_1 Erythromycin esterase - - - 2.501e-246 779.0
HKD2_k127_3085688_2 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 464.0
HKD2_k127_3085688_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000875 245.0
HKD2_k127_3114827_0 transmembrane transport K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 567.0
HKD2_k127_3114827_1 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 527.0
HKD2_k127_3114827_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 440.0
HKD2_k127_3114827_3 TipAS antibiotic-recognition domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 343.0
HKD2_k127_3114827_4 Methyltransferase small domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006118 276.0
HKD2_k127_3114827_7 Belongs to the UPF0176 family K07146 - - 0.0000000000000000002202 87.0
HKD2_k127_3128009_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 7.505e-203 637.0
HKD2_k127_3128009_1 Dehydrogenase E1 component K00161 - 1.2.4.1 6.086e-197 617.0
HKD2_k127_3128009_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 507.0
HKD2_k127_3128009_3 Sh3 type 3 domain protein K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000004028 221.0
HKD2_k127_3128009_4 Biotin-requiring enzyme K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000003024 173.0
HKD2_k127_3128009_5 amino acid K03293,K11735,K16237 - - 0.00000000000000305 76.0
HKD2_k127_3155003_0 DNA topoisomerase (ATP-hydrolyzing) K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 513.0
HKD2_k127_3155003_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002189 238.0
HKD2_k127_3155003_2 - - - - 0.000000000000000000000000000000000009372 138.0
HKD2_k127_3158871_0 permease K06901 - - 8.363e-294 904.0
HKD2_k127_3158871_1 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 453.0
HKD2_k127_3158871_2 N,N-dimethylaniline monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 323.0
HKD2_k127_3158871_3 Copper resistance protein CopC K07156,K14166 - - 0.00000000000000000000000000000000000000000000000000000000000000001568 230.0
HKD2_k127_3158871_4 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide K01479 - 3.5.3.8 0.00000000000000000000000002823 110.0
HKD2_k127_3171634_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 7.632e-252 789.0
HKD2_k127_3171634_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 584.0
HKD2_k127_3171634_2 chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 447.0
HKD2_k127_3171634_3 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 384.0
HKD2_k127_3171634_4 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000001103 196.0
HKD2_k127_3171634_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000008584 113.0
HKD2_k127_317167_0 Thioredoxin-like - - - 0.0 1236.0
HKD2_k127_317167_1 Bacterial protein of unknown function (DUF853) K06915 - - 4.918e-305 941.0
HKD2_k127_317167_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 582.0
HKD2_k127_317167_3 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 577.0
HKD2_k127_317167_4 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 516.0
HKD2_k127_317167_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 511.0
HKD2_k127_317167_6 PFAM ThiJ PfpI domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 391.0
HKD2_k127_317167_7 Copper resistance K02351,K07245 - - 0.00000000001185 64.0
HKD2_k127_3188487_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 512.0
HKD2_k127_3188487_1 LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 398.0
HKD2_k127_3208635_0 Peptidase family M28 - - - 1.907e-274 845.0
HKD2_k127_3208635_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 309.0
HKD2_k127_3212450_0 Dehydrogenase E1 component K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 1.489e-252 781.0
HKD2_k127_3212450_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 479.0
HKD2_k127_3212450_2 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 394.0
HKD2_k127_3212450_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 305.0
HKD2_k127_3248997_0 ABC transporter K06147 - - 3.514e-242 750.0
HKD2_k127_3248997_1 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006603 248.0
HKD2_k127_3255077_0 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 5.344e-220 687.0
HKD2_k127_3255077_1 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 286.0
HKD2_k127_3264302_0 PFAM transposase, IS4 family protein - - - 3.723e-203 646.0
HKD2_k127_3264302_1 iron dependent repressor K02003,K02565,K15545 - - 0.00000000000000000000000000000000000000006897 155.0
HKD2_k127_3266663_0 Two component regulator propeller - - - 5.067e-224 699.0
HKD2_k127_3266663_1 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000000000000000000001003 181.0
HKD2_k127_3266663_2 ThiS family K03636 - - 0.00000000000000000000000000000000001911 136.0
HKD2_k127_3268528_0 Glycosyltransferase like family 2 - - - 2.795e-213 672.0
HKD2_k127_3268528_1 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 510.0
HKD2_k127_3268528_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 480.0
HKD2_k127_3268528_3 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003496 260.0
HKD2_k127_3268528_4 Domain of unknown function (DUF1737) - - - 0.000000000000000000000000000000000000000000000001067 178.0
HKD2_k127_3268528_5 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000003186 181.0
HKD2_k127_3268528_6 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000001444 126.0
HKD2_k127_3287489_0 Biotin carboxylase K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3 3.615e-314 974.0
HKD2_k127_3304331_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 503.0
HKD2_k127_3304331_1 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 390.0
HKD2_k127_3304331_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000001966 213.0
HKD2_k127_3304331_3 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K13940 GO:0008150,GO:0040007 1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000242 143.0
HKD2_k127_3305300_0 - - - - 0.00000000000000000000000000000001508 132.0
HKD2_k127_3305300_1 IMG reference gene - - - 0.000000000000000000002132 106.0
HKD2_k127_3310945_0 Sugar (and other) transporter K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 554.0
HKD2_k127_3310945_1 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 475.0
HKD2_k127_3310945_2 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000000000000000000000000002398 143.0
HKD2_k127_3321116_0 Belongs to the catalase family K03781 - 1.11.1.6 6.165e-304 943.0
HKD2_k127_3321116_1 Transmembrane secretion effector K08225 - - 1.829e-226 706.0
HKD2_k127_3321116_2 Belongs to the Fur family K22297 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 281.0
HKD2_k127_3321116_3 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000003428 209.0
HKD2_k127_3331554_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 390.0
HKD2_k127_3331554_1 Efflux transporter, RND family, MFP subunit K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001888 265.0
HKD2_k127_3331554_2 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.0000000000000000083 91.0
HKD2_k127_3335180_0 Aminotransferase K00826 - 2.6.1.42 8.529e-230 714.0
HKD2_k127_3335180_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 537.0
HKD2_k127_3335180_2 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 507.0
HKD2_k127_3335180_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 402.0
HKD2_k127_3335180_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 0.00000000000000000000000000000000005177 135.0
HKD2_k127_3454418_0 May be required for sporulation K09762 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 - 2.982e-196 613.0
HKD2_k127_3454418_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 426.0
HKD2_k127_3454418_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000005099 217.0
HKD2_k127_3454418_3 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000008779 79.0
HKD2_k127_346272_0 Major facilitator superfamily - - - 1.261e-270 835.0
HKD2_k127_346272_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 552.0
HKD2_k127_346272_2 3-hydroxybutyrate dehydrogenase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 450.0
HKD2_k127_346272_3 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 295.0
HKD2_k127_346272_5 LysR family - - - 0.00000000000000000000000000000002822 128.0
HKD2_k127_3470220_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657 3.3.1.1 1.017e-309 951.0
HKD2_k127_3470220_1 Non-essential cell division protein that could be required for efficient cell constriction - - - 2.295e-208 664.0
HKD2_k127_3470220_2 L,D-transpeptidase catalytic domain - - - 1.476e-204 648.0
HKD2_k127_3470220_3 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 611.0
HKD2_k127_3470220_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 425.0
HKD2_k127_3470220_5 Zincin-like metallopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001219 271.0
HKD2_k127_3470220_6 Protein of unknown function (DUF3499) - - - 0.00000000000000000000000000000000000000000000000000000000000123 213.0
HKD2_k127_3470220_7 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000006425 109.0
HKD2_k127_3470220_8 TIGRFAM integral membrane protein TIGR01906 - - - 0.000000000476 63.0
HKD2_k127_3487300_0 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K10974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 299.0
HKD2_k127_3487300_1 - - - - 0.0000000000000000000000000000000000914 136.0
HKD2_k127_3500446_0 Formamidopyrimidine-DNA glycosylase N-terminal domain K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006891 494.0
HKD2_k127_3500446_1 DEAD DEAH box helicase K03724 - - 0.0000000000000000000000000000000000000000000000000000004788 193.0
HKD2_k127_3500446_2 DEAD/H associated K03724 - - 0.000000000000000000000008473 103.0
HKD2_k127_3500446_3 membrane K07149 - - 0.0000000000000007761 78.0
HKD2_k127_352724_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 484.0
HKD2_k127_352724_1 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 437.0
HKD2_k127_352724_2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001694 273.0
HKD2_k127_352724_3 - - - - 0.00000000000000000000000000000000000006687 147.0
HKD2_k127_3551582_0 DEAD DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0 1203.0
HKD2_k127_3556085_0 McrBC 5-methylcytosine restriction system component K19147 - - 4.049e-219 685.0
HKD2_k127_3556085_1 AAA domain (dynein-related subfamily) K07452 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 429.0
HKD2_k127_3556085_2 May nick specific sequences that contain T G mispairs resulting from m5C-deamination K07458 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003617 254.0
HKD2_k127_3556085_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000004056 83.0
HKD2_k127_3556085_4 EAL domain - - - 0.000005226 55.0
HKD2_k127_3567578_0 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 503.0
HKD2_k127_3567578_1 Lipoate-protein ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 324.0
HKD2_k127_3567578_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 304.0
HKD2_k127_3567578_3 Predicted membrane protein (DUF2177) - - - 0.00000000000000000000000000000000000000000000000000000000003413 207.0
HKD2_k127_3621087_0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 1.955e-203 644.0
HKD2_k127_3621087_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 436.0
HKD2_k127_364364_0 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 527.0
HKD2_k127_364364_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 433.0
HKD2_k127_364364_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 372.0
HKD2_k127_364364_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000003611 206.0
HKD2_k127_364364_4 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000002229 108.0
HKD2_k127_3646205_0 Amidohydrolase family - - - 6.406e-220 688.0
HKD2_k127_3646205_1 prohibitin homologues - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 530.0
HKD2_k127_3646205_2 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 464.0
HKD2_k127_3646205_3 Methyltransferase domain K00563 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 363.0
HKD2_k127_3646205_4 Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters - GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000001485 225.0
HKD2_k127_3646205_5 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000000000000000000000000000000000000000002857 224.0
HKD2_k127_368392_0 DNA helicase - - - 0.0 1321.0
HKD2_k127_368392_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 1.065e-250 778.0
HKD2_k127_368392_2 AlkA N-terminal domain K13529 - 3.2.2.21 4.782e-198 623.0
HKD2_k127_368392_3 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 345.0
HKD2_k127_368392_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002601 278.0
HKD2_k127_368392_5 - - - - 0.0001028 45.0
HKD2_k127_3684199_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 402.0
HKD2_k127_3684199_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000000000000000001806 139.0
HKD2_k127_3684199_2 - - - - 0.00000000000000000000000000000004969 131.0
HKD2_k127_3684199_3 WYL domain K13572,K13573 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000001055 69.0
HKD2_k127_3686393_0 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 468.0
HKD2_k127_3686393_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 374.0
HKD2_k127_3686393_2 Region found in RelA / SpoT proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 345.0
HKD2_k127_3697875_0 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 529.0
HKD2_k127_3697875_1 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000151 198.0
HKD2_k127_3718618_0 Methionine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 496.0
HKD2_k127_3718618_1 response regulator K07670 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 440.0
HKD2_k127_3718618_2 Domain of unknown function (DUF4166) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 397.0
HKD2_k127_3718618_3 Histidine kinase K07636,K07654 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002288 253.0
HKD2_k127_373992_0 response regulator K02483 GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0098771 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 481.0
HKD2_k127_3783657_0 amino acid - - - 3.895e-263 826.0
HKD2_k127_3783657_1 Glutathionylspermidine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 336.0
HKD2_k127_3783657_2 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.00000000002275 64.0
HKD2_k127_3834050_0 Heat shock 70 kDa protein K04043 GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 584.0
HKD2_k127_3834050_1 DnaJ molecular chaperone homology domain K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 452.0
HKD2_k127_3834050_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 368.0
HKD2_k127_3834052_0 Belongs to the carbohydrate kinase PfkB family K00882,K16370 - 2.7.1.11,2.7.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 551.0
HKD2_k127_3834052_1 lacI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 529.0
HKD2_k127_3834052_2 transcriptional regulator, DeoR family K03436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 401.0
HKD2_k127_3834052_3 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 366.0
HKD2_k127_3834052_4 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 285.0
HKD2_k127_3834052_5 PTS system, fructose-specific K02768,K02769,K02770 - 2.7.1.202 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006922 270.0
HKD2_k127_3834052_6 - - - - 0.00000000000000000000000000000000000001578 147.0
HKD2_k127_3839774_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 1.427e-228 715.0
HKD2_k127_3839774_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 297.0
HKD2_k127_3839774_2 Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor K00845,K00886 - 2.7.1.2,2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 293.0
HKD2_k127_3839774_3 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000864 218.0
HKD2_k127_3839842_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.99.16 0.0 1292.0
HKD2_k127_3839842_1 Trehalose synthase K05343 GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576 3.2.1.1,5.4.99.16 2.439e-226 702.0
HKD2_k127_3839842_2 Protein of unknown function (DUF3417) K00688 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1 5.116e-211 660.0
HKD2_k127_3840371_0 Glycosyl hydrolase family 65 central catalytic domain - - - 0.0 1444.0
HKD2_k127_3840371_1 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000003702 93.0
HKD2_k127_3847072_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 322.0
HKD2_k127_3847072_1 LytR cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000000000000000007928 183.0
HKD2_k127_3847072_2 Cold shock protein domain K03704 - - 0.0000000000000000000000000000000006004 132.0
HKD2_k127_3859356_0 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 467.0
HKD2_k127_3859356_1 May play a role in the intracellular transport of hydrophobic ligands - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 397.0
HKD2_k127_3859356_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 388.0
HKD2_k127_3859356_3 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000006351 139.0
HKD2_k127_3859356_5 Transcriptional regulatory protein, C terminal - - - 0.00000000008668 66.0
HKD2_k127_3877106_0 alcohol dehydrogenase K18369 - - 1.902e-206 649.0
HKD2_k127_3877106_1 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 612.0
HKD2_k127_3877106_2 cytochrome C oxidase K02351,K07245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 429.0
HKD2_k127_3877106_3 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004754 296.0
HKD2_k127_3877106_4 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009427 258.0
HKD2_k127_3877106_5 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000008901 204.0
HKD2_k127_3877106_6 Domain of unknown function (DUF4282) - - - 0.000000000000000000000000000004377 125.0
HKD2_k127_3877106_8 Amidohydrolase family - - - 0.0000000000000000000000003332 119.0
HKD2_k127_387852_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 4.276e-223 692.0
HKD2_k127_3880022_0 Transcriptional regulator - - - 4.278e-307 944.0
HKD2_k127_3880022_1 Isocitrate lyase K01637 GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0006950,GO:0008150,GO:0008152,GO:0009268,GO:0009405,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0010033,GO:0010034,GO:0010447,GO:0016020,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019899,GO:0032787,GO:0033554,GO:0033993,GO:0035375,GO:0036293,GO:0036294,GO:0042221,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046421,GO:0046487,GO:0046677,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0070542,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071944,GO:0072350,GO:0075136,GO:0075141,GO:1901700 4.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 500.0
HKD2_k127_3880022_2 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007282 273.0
HKD2_k127_3882748_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 536.0
HKD2_k127_3882748_1 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000001393 187.0
HKD2_k127_3882748_2 - - - - 0.00000000000000000001696 97.0
HKD2_k127_3892752_0 maleylpyruvate isomerase K16163 - 5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 383.0
HKD2_k127_3892752_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000002832 271.0
HKD2_k127_3892752_2 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000739 235.0
HKD2_k127_3900848_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009069,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019752,GO:0019842,GO:0020012,GO:0030170,GO:0030312,GO:0030682,GO:0036094,GO:0042133,GO:0042783,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044464,GO:0046983,GO:0048037,GO:0050662,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0071944,GO:0075136,GO:0097159,GO:1901363,GO:1901564,GO:1901605 2.1.2.1 2.476e-267 825.0
HKD2_k127_3900848_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000001625 247.0
HKD2_k127_3901564_0 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 557.0
HKD2_k127_3901564_1 Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA K00564,K11391 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172,2.1.1.174 0.000000000000000000000000000000000000000000000000000000000000000006747 226.0
HKD2_k127_391073_0 helix_turn_helix, Lux Regulon - - - 1.205e-260 829.0
HKD2_k127_391073_1 luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001028 242.0
HKD2_k127_3912882_0 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 1.571e-220 692.0
HKD2_k127_3912882_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000006347 222.0
HKD2_k127_3921131_0 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 3.755e-291 896.0
HKD2_k127_3921131_1 MATE efflux family protein - - - 6.312e-214 671.0
HKD2_k127_3921131_10 - - - - 0.00000000000000000000000000000000000000000001911 165.0
HKD2_k127_3921131_11 - - - - 0.000000000001597 68.0
HKD2_k127_3921131_2 Thioesterase superfamily K01075,K10806 - 3.1.2.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 613.0
HKD2_k127_3921131_3 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 545.0
HKD2_k127_3921131_4 thymidilate synthase from Mycobacterium tuberculosis. Many phenazine compounds are found in nature and are produced by bacteria such as Pseudomonas spp., Streptomyces spp., and Pantoea agglomerans. These compounds have been implicated in the virulence and competitive fitness of producing organisms. For example, the phenazine pyocyanin produced by Pseudomonas aeruginosa contributes to its ability to colonise the lungs of cystic fibrosis patients. Similarly, phenazine-1-carboxylic acid, produced by a number of Pseudomonas, increases survival in soil environments and has been shown to be essential for the biological control activity of certain strains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 435.0
HKD2_k127_3921131_5 FMN reductase K00299 - 1.5.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 340.0
HKD2_k127_3921131_6 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 309.0
HKD2_k127_3921131_7 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 283.0
HKD2_k127_3921131_8 response to pH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005868 256.0
HKD2_k127_3923701_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.875e-292 900.0
HKD2_k127_3923701_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 1.713e-230 727.0
HKD2_k127_3923701_2 Cysteine desulfurase K04487 GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840 2.8.1.7 1.039e-224 700.0
HKD2_k127_3923701_3 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 439.0
HKD2_k127_3934831_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0 1062.0
HKD2_k127_3934831_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 441.0
HKD2_k127_3934831_2 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 438.0
HKD2_k127_3934831_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008603 266.0
HKD2_k127_3935989_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 495.0
HKD2_k127_3935989_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 484.0
HKD2_k127_3956880_0 RNB K12573 - - 5.314e-276 855.0
HKD2_k127_3956880_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 1.248e-256 793.0
HKD2_k127_3956880_2 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 296.0
HKD2_k127_3956880_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000003609 79.0
HKD2_k127_395833_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 589.0
HKD2_k127_395833_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 437.0
HKD2_k127_3971520_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 508.0
HKD2_k127_3971520_1 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000000000000000000000000000000000000001126 220.0
HKD2_k127_3977144_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1628.0
HKD2_k127_3977144_1 Participates in both transcription termination and antitermination K02600 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 6.485e-202 633.0
HKD2_k127_3977144_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 332.0
HKD2_k127_3977144_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009176 259.0
HKD2_k127_3977144_4 Protein of unknown function (DUF448) K07742 - - 0.000000000000000000000000000000000000000000000008179 175.0
HKD2_k127_3981750_0 Uncharacterised conserved protein (DUF2156) - - - 0.0 1311.0
HKD2_k127_3981750_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 4.087e-308 947.0
HKD2_k127_3981750_10 Type III restriction enzyme, res subunit - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 400.0
HKD2_k127_3981750_11 Protein of unknown function (DUF2550) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001879 261.0
HKD2_k127_3981750_12 Protein of unknown function (DUF3039) - - - 0.0000000000000000000000000000000000000000000000000000001103 196.0
HKD2_k127_3981750_13 ATP- GTP-binding protein - - - 0.000000000000000000000000000000000000000000000000000006366 193.0
HKD2_k127_3981750_14 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000000000003925 145.0
HKD2_k127_3981750_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000002812 83.0
HKD2_k127_3981750_2 - - - - 3.48e-276 861.0
HKD2_k127_3981750_3 NADH flavin oxidoreductase NADH oxidase - - - 3.956e-211 665.0
HKD2_k127_3981750_4 AI-2E family transporter - - - 1.342e-202 637.0
HKD2_k127_3981750_5 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 614.0
HKD2_k127_3981750_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 505.0
HKD2_k127_3981750_7 hydrolase of the alpha beta K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 484.0
HKD2_k127_3981750_8 Tetratricopeptide repeat K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 480.0
HKD2_k127_3981750_9 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 448.0
HKD2_k127_3986303_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 486.0
HKD2_k127_3986303_1 Belongs to the CarA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003351 258.0
HKD2_k127_3986303_2 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000003207 196.0
HKD2_k127_3993456_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.0 1238.0
HKD2_k127_3993456_1 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 2.001e-298 916.0
HKD2_k127_3993456_2 Methionine aminopeptidase K01265 GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 558.0
HKD2_k127_3993456_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 505.0
HKD2_k127_3993456_4 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 340.0
HKD2_k127_3993456_5 - - - - 0.000000000000000000000000003203 111.0
HKD2_k127_4006370_0 ABC transporter substrate-binding protein PnrA-like K07335 - - 2.007e-214 668.0
HKD2_k127_4006370_1 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 605.0
HKD2_k127_4006370_2 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 294.0
HKD2_k127_4006370_3 Organic hydroperoxide resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000001949 203.0
HKD2_k127_40092_0 extracellular solute-binding protein K02027 - - 1.549e-232 724.0
HKD2_k127_40092_1 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 3.822e-196 614.0
HKD2_k127_40092_2 Periplasmic binding proteins and sugar binding domain of LacI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 576.0
HKD2_k127_40092_3 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 550.0
HKD2_k127_40092_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009517 254.0
HKD2_k127_40092_5 - - - - 0.0000000000000000000000000000000008315 132.0
HKD2_k127_4016070_0 Phenol hydroxylase, C-terminal dimerisation domain K03380 - 1.14.13.7 2.954e-237 736.0
HKD2_k127_4016070_1 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 314.0
HKD2_k127_4021837_0 Acyltransferase - - - 1.222e-303 944.0
HKD2_k127_4021837_1 Acyltransferase - - - 1.836e-296 916.0
HKD2_k127_4021837_2 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 450.0
HKD2_k127_4040354_0 amino acid - - - 0.0 1133.0
HKD2_k127_4040354_1 Antar domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 304.0
HKD2_k127_4040354_2 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000003869 160.0
HKD2_k127_4055812_0 ABC transporter - - - 0.0 1099.0
HKD2_k127_4055812_1 Transcriptional regulator, deor family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 375.0
HKD2_k127_4055812_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
HKD2_k127_4055812_3 Penicillin-binding Protein dimerisation domain K01286 - 3.4.16.4 0.000000000000000008082 82.0
HKD2_k127_4067041_0 PFAM Amino acid K11738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 559.0
HKD2_k127_4067041_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000519 237.0
HKD2_k127_4074652_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 476.0
HKD2_k127_4074652_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000003621 179.0
HKD2_k127_4074652_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000004263 181.0
HKD2_k127_4096938_0 Prolyl oligopeptidase K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 387.0
HKD2_k127_4096938_1 oxidoreductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 363.0
HKD2_k127_4108359_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 513.0
HKD2_k127_4108359_1 aldo keto reductase K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 432.0
HKD2_k127_4108359_2 Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.1.1.16,6.3.1.13 0.0000005113 51.0
HKD2_k127_4186590_0 amino acid K03293,K11735,K16237 - - 6.831e-221 696.0
HKD2_k127_4225138_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016020,GO:0016070,GO:0034641,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 574.0
HKD2_k127_4225200_0 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003849 273.0
HKD2_k127_4225200_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000000008006 229.0
HKD2_k127_4225200_3 heat shock protein binding K05516 - - 0.000000000000004897 79.0
HKD2_k127_4271381_0 Glycosyltransferase Family 4 K12583 GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 552.0
HKD2_k127_4271381_1 PFAM Band 7 protein - - - 0.000000000000000000000000000000000001179 140.0
HKD2_k127_4271381_2 - - - - 0.000000000000000000000000000000000003947 138.0
HKD2_k127_4279301_0 Major facilitator superfamily - - - 4.011e-261 812.0
HKD2_k127_4279301_1 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 595.0
HKD2_k127_4279301_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 443.0
HKD2_k127_4279301_3 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 322.0
HKD2_k127_4279301_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002253 245.0
HKD2_k127_4284643_0 cystathionine gamma-synthase K01739,K01758 - 2.5.1.48,4.4.1.1 1.258e-215 677.0
HKD2_k127_4284643_1 DNA polymerase III K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 2.568e-208 660.0
HKD2_k127_4284643_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 343.0
HKD2_k127_4284643_3 TAP-like protein - - - 0.000000000000000000000000000000000000154 145.0
HKD2_k127_4284643_4 Protein of unknown function (DUF2516) - - - 0.0000001116 53.0
HKD2_k127_4292771_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 3.021e-236 737.0
HKD2_k127_4292771_1 Mycothiol-dependent formaldehyde dehydrogenase K00153 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.306 2.146e-220 687.0
HKD2_k127_4292771_2 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 465.0
HKD2_k127_4292771_3 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 378.0
HKD2_k127_4292771_4 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006324 247.0
HKD2_k127_4292771_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008098 239.0
HKD2_k127_4292771_6 Chorismate mutase type II K04782 - 4.2.99.21 0.000000000000000000000000000000000000000000000001797 175.0
HKD2_k127_4292771_7 Glutaredoxin K18917 - 1.20.4.3 0.0000000000000000000000000000000000000000000003595 176.0
HKD2_k127_4292771_8 - - - - 0.00000000000000000000000000000000000000000004928 164.0
HKD2_k127_4292771_9 Protein of unknown function (DUF664) - - - 0.000000000000000004005 86.0
HKD2_k127_4307463_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 589.0
HKD2_k127_4307463_1 Carbon-nitrogen hydrolase K11206 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 401.0
HKD2_k127_4307463_2 Belongs to the glycosyl hydrolase 13 family K01214,K02438 - 3.2.1.196,3.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 319.0
HKD2_k127_4312799_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 429.0
HKD2_k127_4312799_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000002232 211.0
HKD2_k127_4325151_0 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 602.0
HKD2_k127_4325151_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 - 3.5.4.1,3.5.4.33 0.0000000000000000000000000000000000000000000000000278 179.0
HKD2_k127_4325151_2 Glycosyl transferases group 1 - - - 0.0000000000000000002222 90.0
HKD2_k127_4327413_0 Glycosyltransferase family 87 K13671 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 1.109e-206 660.0
HKD2_k127_4327413_1 cystathionine K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 380.0
HKD2_k127_4327413_2 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 356.0
HKD2_k127_4327413_3 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 283.0
HKD2_k127_4342733_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 321.0
HKD2_k127_4342733_1 Belongs to the UPF0225 family K09858 - - 0.0000000000000000000000000000000000000000000000000000000000000006336 223.0
HKD2_k127_4342733_2 Aldo/keto reductase family - - - 0.0000000000000000000000000004629 117.0
HKD2_k127_4358979_0 best DB hits BLAST gb AAD45539.1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006314 267.0
HKD2_k127_4364981_0 Bax inhibitor 1 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 383.0
HKD2_k127_4364981_1 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002079 258.0
HKD2_k127_4396626_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 378.0
HKD2_k127_4396626_1 transposase activity - - - 0.0000000000000000000000000000000000000000000000000028 204.0
HKD2_k127_4396626_2 DDE superfamily endonuclease - - - 0.0006157 42.0
HKD2_k127_4426406_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 615.0
HKD2_k127_4426406_1 Helix-turn-helix domain - - - 0.000000000000000000000000000000000006546 136.0
HKD2_k127_4434781_0 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process K07067 - 2.7.7.85 1.193e-213 665.0
HKD2_k127_4434781_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 6.526e-209 669.0
HKD2_k127_4434781_2 FES K03575 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 505.0
HKD2_k127_4434781_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000103 245.0
HKD2_k127_4434781_4 PTS system fructose IIA component K05881 - 2.7.1.121 0.0000000000000000000000000000000000000000000000001276 179.0
HKD2_k127_4491340_0 iron dependent repressor - - - 2.119e-288 891.0
HKD2_k127_4491340_1 SnoaL-like domain - - - 0.000000000000000000000003718 104.0
HKD2_k127_4506212_0 Dehydrogenase K07077 - - 3.674e-298 921.0
HKD2_k127_4506212_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.5.2,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002188 270.0
HKD2_k127_4506212_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000006446 220.0
HKD2_k127_4520089_0 ANTAR domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 355.0
HKD2_k127_4520089_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 353.0
HKD2_k127_4520089_2 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 296.0
HKD2_k127_4520089_3 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000019 252.0
HKD2_k127_4520089_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000006361 193.0
HKD2_k127_4520089_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000001982 158.0
HKD2_k127_4540055_0 transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 495.0
HKD2_k127_4557881_0 Belongs to the peptidase S8 family K14743 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008437 571.0
HKD2_k127_4557881_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 505.0
HKD2_k127_4557881_2 Protein of unknown function (DUF501) K09009 - - 0.000000000000000000000000000008756 119.0
HKD2_k127_456584_0 DNA alkylation repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 286.0
HKD2_k127_456584_1 integral membrane protein - - - 0.000000000000000000000000000000004354 134.0
HKD2_k127_456584_2 Single-stranded DNA-binding protein K03111 - - 0.0000000000000000000002188 102.0
HKD2_k127_47391_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 408.0
HKD2_k127_47391_1 DoxX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001699 276.0
HKD2_k127_47391_2 Putative zinc-finger - - - 0.000000000000000000000000000000000000000009987 164.0
HKD2_k127_47391_3 Transcriptional regulator - - - 0.000000000000000002958 84.0
HKD2_k127_4749385_0 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 597.0
HKD2_k127_4749385_1 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000002873 194.0
HKD2_k127_4749385_2 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000001474 189.0
HKD2_k127_4749385_3 transcriptional regulator - - - 0.000000000004075 65.0
HKD2_k127_4865602_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 7.043e-266 822.0
HKD2_k127_4865602_1 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 3.34e-258 799.0
HKD2_k127_4875593_0 decarboxylase K01593 - 4.1.1.105,4.1.1.28 1.034e-246 767.0
HKD2_k127_4875593_1 Aminoglycoside/hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 449.0
HKD2_k127_4875593_2 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 374.0
HKD2_k127_4875593_3 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000000000000000000000000000000003827 209.0
HKD2_k127_4875593_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000002026 198.0
HKD2_k127_48875_0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 412.0
HKD2_k127_48875_1 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 293.0
HKD2_k127_48875_2 flagellar hook-associated protein K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000001081 228.0
HKD2_k127_48875_3 bacterial-type flagellum assembly K13626 - - 0.0000000000000000000000000003496 122.0
HKD2_k127_4901945_0 Mur ligase - - - 6.449e-250 779.0
HKD2_k127_4901945_1 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000003948 237.0
HKD2_k127_4901945_2 glutamine amidotransferase K07009 - - 0.0000000000000000000000000000000000000000000000000003754 197.0
HKD2_k127_49441_0 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.795e-317 976.0
HKD2_k127_49441_1 Glyoxalase-like domain - - - 0.00000000000000000307 85.0
HKD2_k127_4972140_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 3.146e-206 643.0
HKD2_k127_4972140_1 Inositol monophosphatase family K01092,K05602 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 505.0
HKD2_k127_5003093_0 Signal transduction histidine kinase regulating citrate malate metabolism K02476 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 436.0
HKD2_k127_5003093_1 Citrate transporter K03300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 392.0
HKD2_k127_5007823_0 alcohol dehydrogenase K13979 - - 1.657e-216 673.0
HKD2_k127_5007823_1 Luciferase-like monooxygenase - - - 2.122e-211 671.0
HKD2_k127_5007823_2 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008502 275.0
HKD2_k127_5009379_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 438.0
HKD2_k127_5009379_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000000000000000000000000000000006709 154.0
HKD2_k127_5009379_2 - - - - 0.00000000000000004201 83.0
HKD2_k127_5010838_0 mandelate racemase muconate lactonizing K08323 GO:0000287,GO:0003674,GO:0005488,GO:0043167,GO:0043169,GO:0046872 4.2.1.8 1.052e-268 828.0
HKD2_k127_5010838_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 392.0
HKD2_k127_5010838_2 PAP2 superfamily K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 359.0
HKD2_k127_5010838_3 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 300.0
HKD2_k127_5010838_4 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000000000000000000001047 147.0
HKD2_k127_5010838_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000421 102.0
HKD2_k127_503540_0 ABC transporter K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 459.0
HKD2_k127_503540_1 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
HKD2_k127_503540_2 Bacterial extracellular solute-binding proteins, family 3 K02029,K02030,K10009 - - 0.00000000000000000000000000000000000000000000000000000000000000004552 223.0
HKD2_k127_503540_3 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000000236 204.0
HKD2_k127_503540_4 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 0.000000000000000000000000000000000000000000000000000000006454 198.0
HKD2_k127_5056562_0 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 319.0
HKD2_k127_5056562_1 Bacterial dnaA protein - - - 0.0000006255 53.0
HKD2_k127_5070890_0 Belongs to the HpcH HpaI aldolase family K01644 GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0071704 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 488.0
HKD2_k127_5070890_1 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 335.0
HKD2_k127_5070890_2 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 313.0
HKD2_k127_5070890_3 3-oxoacid CoA-transferase, B subunit K01029 GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482 2.8.3.5 0.000000000000000000000000000001264 121.0
HKD2_k127_5074398_1 Zinc-dependent metalloprotease - - - 0.0000000000000000000000000005131 127.0
HKD2_k127_5108360_0 Tetratricopeptide repeat - - - 0.00004687 56.0
HKD2_k127_5125507_0 PFAM Rhodanese-like domain - - - 0.000000000000000000000000000000000000007102 153.0
HKD2_k127_5125507_1 pathogenesis K07507 - - 0.000000000000000000000000000000000002569 143.0
HKD2_k127_5125507_2 - - - - 0.00000001644 55.0
HKD2_k127_5125507_3 - - - - 0.000002438 49.0
HKD2_k127_5131726_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 568.0
HKD2_k127_5131726_1 4Fe-4S binding domain K05524 - - 0.0000000000000000000000007677 104.0
HKD2_k127_5131726_2 - - - - 0.000000000000000000000005637 104.0
HKD2_k127_5133483_0 phosphate transporter K03306 - - 1.745e-216 676.0
HKD2_k127_5133483_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 449.0
HKD2_k127_5133483_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 281.0
HKD2_k127_5133483_3 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001471 240.0
HKD2_k127_5133483_4 - - - - 0.0000000000000000000000000001105 115.0
HKD2_k127_5135343_0 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 540.0
HKD2_k127_5135343_1 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 433.0
HKD2_k127_5135343_2 rRNA methyltransferase K00556 - 2.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 418.0
HKD2_k127_5135343_3 Amidohydrolase family K01443 - 3.5.1.25 0.00000001835 55.0
HKD2_k127_5137162_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 345.0
HKD2_k127_5137162_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 330.0
HKD2_k127_5146909_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 1.932e-249 772.0
HKD2_k127_5146909_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 3.287e-218 678.0
HKD2_k127_5146909_2 fructose-bisphosphate aldolase K01624 - 4.1.2.13 2.51e-214 666.0
HKD2_k127_5146909_3 uracil-dna glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 390.0
HKD2_k127_5146909_4 Protein of unknown function (DUF3151) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002105 268.0
HKD2_k127_5146909_5 Amidohydrolase family K01443 - 3.5.1.25 0.00000000000000000000000000000000000001638 148.0
HKD2_k127_5154083_0 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 298.0
HKD2_k127_5154083_1 HutD K09975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 289.0
HKD2_k127_5154083_2 acid phosphatase activity K03651 - 3.1.4.53 0.0000439 46.0
HKD2_k127_5159849_0 ABC transporter K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 425.0
HKD2_k127_5159849_1 Efflux transporter, RND family, MFP subunit K02005,K13888 - - 0.0000000000000000000000000000000000000000855 160.0
HKD2_k127_5162768_0 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007977 484.0
HKD2_k127_5162768_1 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 469.0
HKD2_k127_5162768_2 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 444.0
HKD2_k127_5162768_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 429.0
HKD2_k127_5162768_4 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 414.0
HKD2_k127_5170961_0 Glycoside hydrolase - - - 9.314e-215 669.0
HKD2_k127_5170961_1 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 306.0
HKD2_k127_5181456_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 3.693e-294 909.0
HKD2_k127_5181456_1 - - - - 0.000000000001597 68.0
HKD2_k127_5182054_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 421.0
HKD2_k127_5182054_1 Phage integrase SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 304.0
HKD2_k127_5182054_2 Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000198 242.0
HKD2_k127_5182054_3 phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000004144 233.0
HKD2_k127_5182054_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000446 238.0
HKD2_k127_5182054_5 Integrase - - - 0.0000000000000000001964 89.0
HKD2_k127_5193148_0 helicase - - - 0.0 1027.0
HKD2_k127_5193148_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 578.0
HKD2_k127_5193148_2 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 395.0
HKD2_k127_5193148_3 transporter K03761 - - 0.000000000000000000000000007869 109.0
HKD2_k127_5196740_0 Glycosyltransferase family 87 - - - 4.841e-243 758.0
HKD2_k127_5196740_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 546.0
HKD2_k127_5202060_0 Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000005401 205.0
HKD2_k127_5202060_1 Belongs to the 'phage' integrase family K03733 - - 0.000000002364 64.0
HKD2_k127_5204547_0 Rossmann fold nucleotide-binding protein - - - 6.762e-197 618.0
HKD2_k127_5204547_1 Matrixin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 424.0
HKD2_k127_5204547_2 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 333.0
HKD2_k127_5204547_3 PFAM Polyketide cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001501 256.0
HKD2_k127_5204547_4 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000005051 198.0
HKD2_k127_5219616_0 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001311 285.0
HKD2_k127_5219616_1 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000000000000000000000000003801 153.0
HKD2_k127_5219616_2 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0000000000000000000000000000000006907 132.0
HKD2_k127_5219616_3 double-strand break repair K09946 - - 0.00000000000000000000000000025 119.0
HKD2_k127_5223711_0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 516.0
HKD2_k127_5223711_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001025 255.0
HKD2_k127_5223711_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000002291 154.0
HKD2_k127_5243595_0 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 555.0
HKD2_k127_5243595_1 ABC transporter K02017,K02018 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 479.0
HKD2_k127_5243595_2 ABC transporter K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 395.0
HKD2_k127_5243595_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000003135 73.0
HKD2_k127_5248338_0 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 298.0
HKD2_k127_5248338_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000184 263.0
HKD2_k127_5248338_2 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001432 256.0
HKD2_k127_5248338_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000008891 216.0
HKD2_k127_5248338_6 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0004005 46.0
HKD2_k127_5251225_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 1.592e-196 619.0
HKD2_k127_5251225_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000188 282.0
HKD2_k127_5251225_2 Fusaric acid resistance protein-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009445 238.0
HKD2_k127_5253312_0 Cation transporting ATPase, C-terminus K01537 - 3.6.3.8 0.0 1142.0
HKD2_k127_5253312_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000005395 167.0
HKD2_k127_5254193_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 2.407e-287 889.0
HKD2_k127_5254193_1 Pfam:PNPOx_C K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000006704 202.0
HKD2_k127_5254193_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000004383 136.0
HKD2_k127_5263522_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 556.0
HKD2_k127_5263522_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000138 198.0
HKD2_k127_5264802_0 AMP-binding enzyme K01897 - 6.2.1.3 3.104e-217 683.0
HKD2_k127_5264802_1 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 535.0
HKD2_k127_5264802_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 541.0
HKD2_k127_5264802_3 ATPases associated with a variety of cellular activities K16784 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 332.0
HKD2_k127_5264802_4 Cobalt transport protein K16783 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 307.0
HKD2_k127_5264802_5 BioY family K03523 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 290.0
HKD2_k127_5264802_6 Putative neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.00000006699 59.0
HKD2_k127_5282125_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 8.208e-259 811.0
HKD2_k127_5282125_1 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 394.0
HKD2_k127_5282125_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278,K00767 GO:0008150,GO:0040007 1.4.3.16,2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006295 293.0
HKD2_k127_5288375_0 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 465.0
HKD2_k127_5288375_1 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 449.0
HKD2_k127_5288375_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 289.0
HKD2_k127_5288375_3 YCII-related domain - - - 0.00000000000000000000000000000000000000000000009768 174.0
HKD2_k127_529597_0 Phosphate transport system permease protein PstA K02038 - - 4.889e-208 649.0
HKD2_k127_529597_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 357.0
HKD2_k127_529597_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000005974 171.0
HKD2_k127_5299857_0 transposition K07497 - - 0.00000000000000000000000000000000000000000000000000000005007 211.0
HKD2_k127_5300594_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1439.0
HKD2_k127_5300594_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000855 218.0
HKD2_k127_5303072_0 Aminotransferase - - - 1.341e-219 684.0
HKD2_k127_5303072_1 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 321.0
HKD2_k127_5308637_0 Radical SAM - - - 2.643e-202 636.0
HKD2_k127_5308637_1 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008669 270.0
HKD2_k127_5308637_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000003751 189.0
HKD2_k127_5314423_0 Phospholipase D Transphosphatidylase - - - 2.703e-267 831.0
HKD2_k127_5314423_1 Sulfate permease family K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 612.0
HKD2_k127_5314423_2 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 380.0
HKD2_k127_5314423_3 membrane K00389 - - 0.0000000000000000000000000000000000000000000005641 170.0
HKD2_k127_5314423_4 Domain of unknown function (DUF4287) - - - 0.0000000000000000000000000000000000139 151.0
HKD2_k127_5314423_5 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000003531 100.0
HKD2_k127_5323194_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 446.0
HKD2_k127_5323194_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 311.0
HKD2_k127_5323194_2 Activator of hsp90 atpase 1 family protein - - - 0.000000000000000000000000000000000000000000000000000000000808 205.0
HKD2_k127_5326016_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 367.0
HKD2_k127_5326016_1 Tyrosine phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 319.0
HKD2_k127_5326016_2 polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000008463 207.0
HKD2_k127_5326016_3 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000001437 179.0
HKD2_k127_5326016_4 cellulase activity - - - 0.0000000000000000000000000000000006346 137.0
HKD2_k127_5339628_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 4.175e-303 929.0
HKD2_k127_5339628_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002338 255.0
HKD2_k127_5344864_0 Cation transport protein K03498 - - 9.008e-266 823.0
HKD2_k127_5344864_1 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 413.0
HKD2_k127_5344864_2 acetoin utilization protein K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006924 366.0
HKD2_k127_5344864_3 PFAM HhH-GPD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003048 229.0
HKD2_k127_5362430_0 Berberine and berberine like - - - 9.542e-225 704.0
HKD2_k127_5362430_1 TOBE domain - - - 0.000000000003019 67.0
HKD2_k127_5364325_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1049.0
HKD2_k127_5364325_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0002769 49.0
HKD2_k127_5371246_0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 497.0
HKD2_k127_5371246_1 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 499.0
HKD2_k127_5371246_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 479.0
HKD2_k127_5371246_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 451.0
HKD2_k127_5371246_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 342.0
HKD2_k127_5371246_5 DivIVA domain repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009964 321.0
HKD2_k127_5371246_6 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 299.0
HKD2_k127_5375249_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 552.0
HKD2_k127_5375249_1 Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 444.0
HKD2_k127_5376095_0 aldo keto reductase K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 517.0
HKD2_k127_5376095_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 330.0
HKD2_k127_5376095_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000003763 163.0
HKD2_k127_5380093_0 Peptidase family M20/M25/M40 K01436,K06048 - - 1.849e-247 765.0
HKD2_k127_5380093_1 mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 356.0
HKD2_k127_5380093_2 transcriptional regulator - - - 0.0000000000000000000000000000000000003061 141.0
HKD2_k127_5382232_0 acetylornithine K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 3.982e-227 709.0
HKD2_k127_5382232_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000004968 177.0
HKD2_k127_5382232_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000009229 79.0
HKD2_k127_5386182_0 Glycosyltransferase family 87 K13671 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 456.0
HKD2_k127_5386182_1 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 441.0
HKD2_k127_5396309_0 best DB hits BLAST gb AAD45539.1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004253 266.0
HKD2_k127_5396309_1 lipolytic protein G-D-S-L family - - - 0.000002452 51.0
HKD2_k127_54151_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 403.0
HKD2_k127_54151_1 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000148 215.0
HKD2_k127_5424067_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 491.0
HKD2_k127_5424067_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 411.0
HKD2_k127_5424067_2 amidohydrolase - - - 0.0000000007474 66.0
HKD2_k127_5431775_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 395.0
HKD2_k127_5431775_1 protein import - - - 0.00000000000000000000000000005663 123.0
HKD2_k127_5438008_0 amino acid K11735,K16237 - - 7.918e-262 811.0
HKD2_k127_5438008_1 M18 family aminopeptidase K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.21 3.056e-256 796.0
HKD2_k127_5438008_2 Diacylglycerol kinase catalytic domain (presumed) K19302 - 3.6.1.27 1.584e-253 788.0
HKD2_k127_5438008_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 526.0
HKD2_k127_5438008_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 383.0
HKD2_k127_5438008_5 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 346.0
HKD2_k127_5438008_6 Protein of unknown function (DUF1345) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 317.0
HKD2_k127_5438008_7 transporter K03761 - - 0.00000003677 55.0
HKD2_k127_5440693_0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 514.0
HKD2_k127_5440693_1 protocatechuate 3,4-dioxygenase K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 476.0
HKD2_k127_5447462_0 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 498.0
HKD2_k127_5447462_1 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 416.0
HKD2_k127_5447462_2 PFAM Transposase DDE domain - - - 0.00000004052 54.0
HKD2_k127_5452933_0 Putative exonuclease SbcCD, C subunit - - - 0.0 1540.0
HKD2_k127_5452933_1 FBP C-terminal treble-clef zinc-finger - - - 0.00000000000000000000000000000000000000000000000000000378 191.0
HKD2_k127_5470894_0 3'-5' exonuclease K03684 - 3.1.13.5 4.429e-254 787.0
HKD2_k127_5470894_1 Protein of unknown function (DUF3000) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 368.0
HKD2_k127_5470894_2 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000005233 178.0
HKD2_k127_5472123_0 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 362.0
HKD2_k127_5472123_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 301.0
HKD2_k127_5472123_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000007538 261.0
HKD2_k127_5472123_3 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000006272 199.0
HKD2_k127_5475904_0 Binding-protein-dependent transport system inner membrane component K02033 - - 1.023e-210 657.0
HKD2_k127_5475904_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002111 258.0
HKD2_k127_5475904_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000349 193.0
HKD2_k127_5498895_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 4.841e-243 752.0
HKD2_k127_5498895_1 PFAM YCII-related K09780 - - 0.0000000000000000000000000000000000000000003098 159.0
HKD2_k127_5498895_2 - - - - 0.0000002859 51.0
HKD2_k127_5498895_3 Domain of unknown function (DUF4081) K06976 - - 0.0004845 45.0
HKD2_k127_5502594_0 Glycosyl transferases group 1 - - - 2.006e-202 647.0
HKD2_k127_5502594_1 PFAM alpha beta hydrolase fold K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 459.0
HKD2_k127_5502594_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 357.0
HKD2_k127_5502594_3 Aldo/keto reductase family K06221 - 1.1.1.346 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 344.0
HKD2_k127_550438_0 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 569.0
HKD2_k127_550438_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 509.0
HKD2_k127_550438_2 Involved in chromosome - - - 0.000000009442 61.0
HKD2_k127_5509151_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 2.416e-315 968.0
HKD2_k127_5509151_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 367.0
HKD2_k127_5509151_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000002725 49.0
HKD2_k127_5514990_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 3.727e-222 697.0
HKD2_k127_5514990_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 7.917e-219 683.0
HKD2_k127_5514990_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 4.693e-196 644.0
HKD2_k127_5514990_3 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 505.0
HKD2_k127_5518334_0 Methicillin resistance protein - - - 1.794e-229 712.0
HKD2_k127_5518334_1 Threonine/Serine exporter, ThrE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 563.0
HKD2_k127_5549212_0 Major Facilitator - - - 5.174e-220 685.0
HKD2_k127_5549212_1 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 505.0
HKD2_k127_5559999_0 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000009372 180.0
HKD2_k127_5559999_1 FAD binding domain - - - 0.0000000000000000000000000000000000000001983 153.0
HKD2_k127_5559999_2 - - - - 0.000000000000000000000000000000002453 143.0
HKD2_k127_5564189_0 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 537.0
HKD2_k127_5564189_1 GDP-mannose 4,6 dehydratase K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 511.0
HKD2_k127_5564189_2 Glycosyltransferase family 87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 427.0
HKD2_k127_5564189_3 Phosphorylase superfamily K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 310.0
HKD2_k127_5564189_4 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000833 249.0
HKD2_k127_5564189_5 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008864 249.0
HKD2_k127_5564189_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000007014 241.0
HKD2_k127_5564189_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000001153 220.0
HKD2_k127_5564189_8 - - - - 0.0000000000001666 79.0
HKD2_k127_5583747_0 UPF0126 domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 372.0
HKD2_k127_5583747_1 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 330.0
HKD2_k127_5583747_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 287.0
HKD2_k127_5602028_0 Peptidase dimerisation domain - - - 2.122e-260 816.0
HKD2_k127_5602028_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.5.2,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 426.0
HKD2_k127_5602028_2 Protein of unknown function (DUF3043) - GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 325.0
HKD2_k127_5602028_3 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000871 237.0
HKD2_k127_5606897_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 9.437e-203 633.0
HKD2_k127_5606897_1 Pyruvate dehydrogenase K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 407.0
HKD2_k127_5606897_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000008683 239.0
HKD2_k127_5653726_0 ANTAR domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 416.0
HKD2_k127_5656498_0 required for the transposition of insertion element IS2404 - - - 0.000000000000000000000000000000000000001613 160.0
HKD2_k127_5656498_1 UTRA K11922 - - 0.00000000000002322 74.0
HKD2_k127_5660788_0 NAD dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 507.0
HKD2_k127_5660788_1 ERAP1-like C-terminal domain K01256,K08776 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 406.0
HKD2_k127_5660788_2 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 334.0
HKD2_k127_5660788_3 Bacterial-like globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 306.0
HKD2_k127_5660788_4 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003529 269.0
HKD2_k127_5660788_5 Trehalose synthase - - - 0.00000000000000000000000000000000000000000000000000001116 204.0
HKD2_k127_5660788_6 phosphinothricin N-acetyltransferase activity K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000008635 184.0
HKD2_k127_5660788_7 - - - - 0.00000000000004331 72.0
HKD2_k127_5665683_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 1.977e-283 872.0
HKD2_k127_5665683_1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768 - 2.7.1.202 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 295.0
HKD2_k127_5665683_2 SURF1 family - - - 0.00000000000000000013 88.0
HKD2_k127_5672539_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 387.0
HKD2_k127_5672539_1 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004833 224.0
HKD2_k127_5672539_2 peptidase K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000005612 183.0
HKD2_k127_56814_0 helicase - - - 0.0 1103.0
HKD2_k127_56814_1 DNA polymerase III K02337,K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 409.0
HKD2_k127_56814_2 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.000000000000000000000000000000000000000000000000000000002574 209.0
HKD2_k127_5745716_0 recombinase activity K03601,K13582 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 361.0
HKD2_k127_5745716_1 DDE_Tnp_1-associated - - - 0.0000000000000000134 86.0
HKD2_k127_5745716_2 Domain of unknown function DUF11 - - - 0.00000000002571 67.0
HKD2_k127_5746660_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 357.0
HKD2_k127_5746660_1 COG3385 FOG Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 325.0
HKD2_k127_5746660_2 IstB-like ATP binding protein - - - 0.0000000000000000000000002382 117.0
HKD2_k127_5768772_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 524.0
HKD2_k127_5768772_1 penicillin-binding protein - - - 0.000000000000000000000000000000000000001524 152.0
HKD2_k127_5768772_2 PFAM regulatory protein, MarR - - - 0.00000006964 54.0
HKD2_k127_5788068_0 PFAM Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000246 271.0
HKD2_k127_5788068_1 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000326 74.0
HKD2_k127_5800842_0 iron dependent repressor K02003,K02565,K15545 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 475.0
HKD2_k127_5800842_1 - - - - 0.000000000000000000000000000000000000000000000001328 178.0
HKD2_k127_5800842_2 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000001149 167.0
HKD2_k127_5803650_0 Belongs to the MenA family. Type 1 subfamily K02548 GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 517.0
HKD2_k127_5803650_1 AMP-binding enzyme K01911,K02549 - 4.2.1.113,6.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 356.0
HKD2_k127_5803650_2 Protein of unknown function (DUF4229) - - - 0.00000000000000000000000000000000000000002643 154.0
HKD2_k127_5803650_3 Phospholipase_D-nuclease N-terminal - - - 0.00001077 47.0
HKD2_k127_5813836_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0 1770.0
HKD2_k127_5813836_1 Belongs to the peptidase S16 family K07177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 553.0
HKD2_k127_5813836_2 Zincin-like metallopeptidase - - - 0.00000000000000000000000003219 108.0
HKD2_k127_5813836_3 - - - - 0.00000001716 58.0
HKD2_k127_5845041_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 394.0
HKD2_k127_5845041_1 Transcriptional regulator K21961 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000123 214.0
HKD2_k127_5845041_2 Flavoprotein involved in K transport K10215 - - 0.00000000000000000000000000000000000000000000000000009793 188.0
HKD2_k127_5845041_3 lactoylglutathione lyase activity - - - 0.0000000000001251 71.0
HKD2_k127_5861890_0 Belongs to the malate synthase family K01638 - 2.3.3.9 0.0 1013.0
HKD2_k127_5871117_0 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 374.0
HKD2_k127_5871117_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006131 264.0
HKD2_k127_5871117_2 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592,K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.000000000000000000000000000000000000000000000002759 178.0
HKD2_k127_5871117_3 Glutathionylspermidine synthase - - - 0.0000000000000000000000000000000006208 132.0
HKD2_k127_590101_0 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 486.0
HKD2_k127_590101_1 - - - - 0.000000000000000000000000000000000000000000002372 175.0
HKD2_k127_590101_2 Thioesterase superfamily - - - 0.00000000004478 63.0
HKD2_k127_5905528_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 447.0
HKD2_k127_5905528_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000257 261.0
HKD2_k127_5905528_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000006706 191.0
HKD2_k127_5931680_0 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 449.0
HKD2_k127_5931680_1 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 388.0
HKD2_k127_5931680_2 polysaccharide biosynthetic process K07015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005093 257.0
HKD2_k127_5931680_3 Peptidase dimerisation domain K13049 - - 0.000000000002821 73.0
HKD2_k127_5954151_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 8.222e-308 945.0
HKD2_k127_5954151_1 Putative inner membrane exporter, YdcZ K09936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 510.0
HKD2_k127_5954151_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 310.0
HKD2_k127_5954151_3 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005154 244.0
HKD2_k127_5954151_4 S4 domain K14761 - - 0.000000000000000000000000000000003154 138.0
HKD2_k127_5962434_0 PTS system, fructose-specific K02768,K02769,K02770 - 2.7.1.202 1.602e-286 882.0
HKD2_k127_5962434_1 PTS HPr component phosphorylation site K11189 - - 0.00000000000000000000000000000000000000000004684 163.0
HKD2_k127_5982154_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 602.0
HKD2_k127_5982154_1 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 368.0
HKD2_k127_5982154_2 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000003949 198.0
HKD2_k127_5982154_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 0.00000000000000000000000000000000000000000000005631 169.0
HKD2_k127_5982154_4 integration host factor - - - 0.000000000000000000000000000000000000001316 157.0
HKD2_k127_6034291_0 phosphatase K20074 GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 560.0
HKD2_k127_6034291_1 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 393.0
HKD2_k127_6034291_2 Forkhead associated domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 301.0
HKD2_k127_6041575_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 489.0
HKD2_k127_6041575_1 DegV family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 487.0
HKD2_k127_6041575_2 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.0000000000000000000000000000000000000000000000000000000000000004499 229.0
HKD2_k127_6041575_3 Competence protein K02238 - - 0.00000000000000000001329 104.0
HKD2_k127_6092889_0 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 5.33e-212 667.0
HKD2_k127_6092889_1 synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 415.0
HKD2_k127_614418_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 449.0
HKD2_k127_614418_1 Carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 357.0
HKD2_k127_614418_2 Virulence activator alpha C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 283.0
HKD2_k127_6177825_0 PFAM Integrase, catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 471.0
HKD2_k127_6177825_1 IstB domain protein ATP-binding protein - - - 0.0000000000107 69.0
HKD2_k127_6177825_2 Homeodomain-like domain - - - 0.000006792 48.0
HKD2_k127_6221701_0 transcriptional regulator, TetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 357.0
HKD2_k127_6221701_1 Antar domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005193 266.0
HKD2_k127_6221701_2 TspO/MBR family K05770 - - 0.00000000000000000000000000000000000000000000000000000000000000006317 227.0
HKD2_k127_6224463_0 Acetyl xylan esterase (AXE1) - - - 2.5e-323 1001.0
HKD2_k127_6224463_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 323.0
HKD2_k127_6224463_2 - - - - 0.0000000000000000000000005591 104.0
HKD2_k127_6239601_0 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 548.0
HKD2_k127_6239601_1 - - - - 0.00000000000000000000001583 107.0
HKD2_k127_6288033_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000537 274.0
HKD2_k127_6288033_1 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006078 250.0
HKD2_k127_6288033_2 transposase - - - 0.0000000001006 62.0
HKD2_k127_62941_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 575.0
HKD2_k127_62941_1 DNA polymerase alpha chain like domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 494.0
HKD2_k127_62941_2 UPF0056 membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 325.0
HKD2_k127_632598_0 transposase activity - - - 0.0000000000000000000000000000000000000000000557 169.0
HKD2_k127_632598_1 Protein tyrosine serine phosphatase - - - 0.000000000000000000000000000000000000001141 151.0
HKD2_k127_632598_2 required for the transposition of insertion element IS2404 - - - 0.0000000000000000000000000008026 119.0
HKD2_k127_632598_3 DDE_Tnp_1-associated - - - 0.000000002101 68.0
HKD2_k127_6331546_0 Prephenate dehydrogenase K04517 - 1.3.1.12 1.949e-204 657.0
HKD2_k127_6331546_1 Belongs to the pseudouridine synthase RsuA family K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 3.881e-204 644.0
HKD2_k127_6331546_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 425.0
HKD2_k127_6331546_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 366.0
HKD2_k127_6331546_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 331.0
HKD2_k127_636366_0 Putative exonuclease SbcCD, C subunit K03546 - - 0.0 1172.0
HKD2_k127_636366_1 Major facilitator superfamily - - - 1.742e-268 831.0
HKD2_k127_636366_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 7.213e-204 639.0
HKD2_k127_636366_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 538.0
HKD2_k127_636366_4 IclR helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 389.0
HKD2_k127_636366_5 DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 382.0
HKD2_k127_636366_6 Major intrinsic protein K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 365.0
HKD2_k127_636366_7 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 336.0
HKD2_k127_636366_8 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000000000000000000000009467 180.0
HKD2_k127_636366_9 Sh3 type 3 domain protein - - - 0.00000000000004767 79.0
HKD2_k127_6388987_0 Rhodopirellula transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 527.0
HKD2_k127_6399775_0 Tex-like protein N-terminal domain K06959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 586.0
HKD2_k127_6399775_1 SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 293.0
HKD2_k127_6399775_2 RNase_H superfamily - - - 0.00000000000000000000000000000000000000000000000000000003229 211.0
HKD2_k127_6399915_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 593.0
HKD2_k127_6399915_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000006674 187.0
HKD2_k127_6399915_3 COG0500 SAM-dependent methyltransferases - - - 0.000000007774 56.0
HKD2_k127_6401612_0 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 377.0
HKD2_k127_6401612_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 298.0
HKD2_k127_6401612_2 Purine catabolism regulatory protein-like family K09684 - - 0.00000000000000000000000000004925 115.0
HKD2_k127_6409223_0 PFAM Transposase, Mutator - - - 1.203e-196 616.0
HKD2_k127_6409223_1 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003677 248.0
HKD2_k127_6409223_2 Lipopolysaccharide assembly protein A domain - - - 0.000000000000000000000112 109.0
HKD2_k127_6409650_0 transporter K03761 - - 1.765e-210 657.0
HKD2_k127_6409650_1 Phosphomethylpyrimidine kinase K00868,K00941 - 2.7.1.35,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 501.0
HKD2_k127_6425022_0 transposase activity - - - 9.563e-220 689.0
HKD2_k127_6425022_1 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000004201 202.0
HKD2_k127_6425545_0 Glycosyl hydrolase family 65, C-terminal domain K05342 - 2.4.1.64 1.36e-209 661.0
HKD2_k127_6425545_1 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000001499 201.0
HKD2_k127_6427771_0 Pyruvate dehydrogenase K00161,K00166 - 1.2.4.1,1.2.4.4 9.468e-230 715.0
HKD2_k127_6427771_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 9.998e-220 689.0
HKD2_k127_6427771_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 338.0
HKD2_k127_6427771_3 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 286.0
HKD2_k127_6427771_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000007927 210.0
HKD2_k127_6432462_0 Major Facilitator Superfamily - - - 0.0000000000000000003673 100.0
HKD2_k127_6433716_0 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000004251 211.0
HKD2_k127_6433716_1 lytic transglycosylase activity K21687 - - 0.0000000000000000000000003519 108.0
HKD2_k127_6433716_2 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000002456 81.0
HKD2_k127_6433716_3 Lysyl oxidase - - - 0.0000000000000001186 91.0
HKD2_k127_6433716_4 response regulator, receiver K02483,K07667 - - 0.00000000000003507 72.0
HKD2_k127_6435144_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 2.405e-200 626.0
HKD2_k127_6435144_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 585.0
HKD2_k127_6435144_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 314.0
HKD2_k127_6458652_0 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0051704 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 401.0
HKD2_k127_6458652_1 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 326.0
HKD2_k127_6458652_2 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 310.0
HKD2_k127_6458652_3 DEAD DEAH box helicase - - - 0.000000000000000000000000000000000000001136 149.0
HKD2_k127_6466049_0 synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 456.0
HKD2_k127_6466049_1 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 346.0
HKD2_k127_6466049_2 - - - - 0.0000000000000000000000000000000000000000000000001318 177.0
HKD2_k127_6472803_0 Luciferase-like monooxygenase - - - 2.254e-288 888.0
HKD2_k127_6472803_1 Acyl-CoA dehydrogenases catalyze the alpha,beta-dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD - - - 1.967e-209 657.0
HKD2_k127_6472803_10 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000000000000000000001589 163.0
HKD2_k127_6472803_2 NLPA lipoprotein K02073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 531.0
HKD2_k127_6472803_3 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system K02071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 430.0
HKD2_k127_6472803_4 Binding-protein-dependent transport system inner membrane component K02072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 383.0
HKD2_k127_6472803_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 349.0
HKD2_k127_6472803_6 YjbR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004219 239.0
HKD2_k127_6472803_7 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000001269 240.0
HKD2_k127_6472803_8 PFAM regulatory protein, MarR - - - 0.000000000000000000000000000000000000000000000000000000000000001959 221.0
HKD2_k127_6472803_9 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000003701 209.0
HKD2_k127_6482904_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 5.238e-249 771.0
HKD2_k127_6482904_1 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000002899 128.0
HKD2_k127_6484023_0 Phenylacetate-CoA oxygenase K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 526.0
HKD2_k127_6484023_1 Phenylacetate-CoA oxygenase K02612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 312.0
HKD2_k127_6484023_2 Phenylacetate-CoA oxygenase reductase, PaaK subunit K02613 - - 0.0000000000000006218 78.0
HKD2_k127_6490014_0 carboxylase K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 1.057e-203 636.0
HKD2_k127_6490014_1 Maf-like protein K06287 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 369.0
HKD2_k127_6495385_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 6.673e-313 966.0
HKD2_k127_6495385_1 PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003233 250.0
HKD2_k127_6495385_2 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000001988 139.0
HKD2_k127_6500223_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 2.319e-246 762.0
HKD2_k127_6500223_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000001559 195.0
HKD2_k127_6501965_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11103 - - 3.371e-248 774.0
HKD2_k127_6501965_1 Cellulose biosynthesis protein BcsQ K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 580.0
HKD2_k127_6501965_2 Single cache domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 294.0
HKD2_k127_6512915_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain K21023 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 394.0
HKD2_k127_6512915_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000003665 220.0
HKD2_k127_6512915_2 - - - - 0.00000000000000000000000000000000000000000000000001068 182.0
HKD2_k127_6512915_3 - - - - 0.000003356 51.0
HKD2_k127_6528028_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0 1071.0
HKD2_k127_6528028_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K15580 - - 0.0 1058.0
HKD2_k127_6528028_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0 1006.0
HKD2_k127_6528028_3 Belongs to the ABC transporter superfamily K02031,K02032 - - 1e-323 997.0
HKD2_k127_6528028_4 Binding-protein-dependent transport system inner membrane component K02033 - - 5.747e-284 879.0
HKD2_k127_6528028_5 Binding-protein-dependent transport system inner membrane component K02034 - - 9.137e-195 612.0
HKD2_k127_6528028_6 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 595.0
HKD2_k127_6528028_7 Binding-protein-dependent transport system inner membrane component K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 442.0
HKD2_k127_6528028_8 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 318.0
HKD2_k127_6531487_0 Tryptophanyl-tRNA synthetase K01867 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.2 2.294e-197 619.0
HKD2_k127_6531487_1 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 468.0
HKD2_k127_6531487_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000001238 167.0
HKD2_k127_6531487_3 2'-5' RNA ligase superfamily - - - 0.000000000000000000000000000000000000000000002721 174.0
HKD2_k127_6550360_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 404.0
HKD2_k127_6550360_1 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.00000000000000000000000000000000000000000000000000003379 195.0
HKD2_k127_6557371_0 ABC-2 family transporter protein K01421 - - 6.695e-321 993.0
HKD2_k127_6557371_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 326.0
HKD2_k127_6557371_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 348.0
HKD2_k127_6557371_3 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 327.0
HKD2_k127_6566271_0 NlpC/P60 family K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 507.0
HKD2_k127_6566271_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 387.0
HKD2_k127_6566271_2 Zincin-like metallopeptidase - - - 0.00000000000000000000000000000000000000000000002765 169.0
HKD2_k127_6585402_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1218.0
HKD2_k127_6585402_1 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 286.0
HKD2_k127_6589480_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 597.0
HKD2_k127_6589480_1 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000000000000000009801 226.0
HKD2_k127_6589480_2 - - - - 0.000000000000000000000000000000000000000000000000000009997 194.0
HKD2_k127_6589480_3 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.000000000000003342 76.0
HKD2_k127_6589681_0 PFAM alpha amylase, catalytic K01187 - 3.2.1.20 0.0 1013.0
HKD2_k127_6601956_0 PFAM Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 319.0
HKD2_k127_6601956_1 IMG reference gene - - - 0.0000000000005132 73.0
HKD2_k127_6612016_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 5.593e-235 734.0
HKD2_k127_6612016_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 273.0
HKD2_k127_6612016_2 Nitrite reductase NAD(P)H , small subunit K00363 - 1.7.1.15 0.00000000000000000000000000000000000000000000000109 179.0
HKD2_k127_6623670_0 cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 367.0
HKD2_k127_6623670_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 327.0
HKD2_k127_6630289_0 helix_turn_helix, Lux Regulon - - - 0.0 1043.0
HKD2_k127_6630289_1 PFAM regulatory protein LuxR - - - 1.921e-301 932.0
HKD2_k127_6630289_2 luxR family - - - 1.142e-274 868.0
HKD2_k127_6649276_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006362 256.0
HKD2_k127_6649276_1 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000000000000000000000000000000000000000000000000001665 204.0
HKD2_k127_6649276_2 - - - - 0.000000007603 59.0
HKD2_k127_6651921_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0008150,GO:0040007 - 1.974e-196 623.0
HKD2_k127_6651921_1 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 357.0
HKD2_k127_6651921_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000007855 218.0
HKD2_k127_6651921_3 AntiSigma factor - - - 0.00000007591 57.0
HKD2_k127_667_0 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 484.0
HKD2_k127_667_1 Flagellar assembly protein FliH K02411 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 327.0
HKD2_k127_667_2 flagellar motor switch protein FliG K02410 - - 0.000000000000000000000000000000000000008136 145.0
HKD2_k127_6672563_0 Domain of unknown function (DUF4081) K06976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 433.0
HKD2_k127_6672563_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 0.00000000000000000000000000000000000000000000000000006023 188.0
HKD2_k127_6680528_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 2.107e-210 656.0
HKD2_k127_6680528_1 Zincin-like metallopeptidase - - - 2.346e-200 639.0
HKD2_k127_6680528_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075 GO:0008150,GO:0040007 2.4.2.8,6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 541.0
HKD2_k127_6680528_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 364.0
HKD2_k127_6680528_4 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000003903 258.0
HKD2_k127_6689930_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.69e-303 936.0
HKD2_k127_6689930_1 malate quinone oxidoreductase K00116 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0044424,GO:0044464,GO:0055114,GO:0071944 1.1.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 443.0
HKD2_k127_6689930_2 Fasciclin - GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043207,GO:0044403,GO:0044419,GO:0044421,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 346.0
HKD2_k127_6689930_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002542 273.0
HKD2_k127_6689930_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001762 239.0
HKD2_k127_6689930_5 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome - - - 0.00000000000000000002897 91.0
HKD2_k127_6689930_6 Phage integrase family - - - 0.00002068 48.0
HKD2_k127_6726490_0 Oxidoreductase molybdopterin binding - - - 2.392e-196 629.0
HKD2_k127_6726490_1 molybdenum cofactor K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 573.0
HKD2_k127_6726490_10 MoaE protein K03635 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000005646 258.0
HKD2_k127_6726490_2 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 566.0
HKD2_k127_6726490_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 542.0
HKD2_k127_6726490_4 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 515.0
HKD2_k127_6726490_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 435.0
HKD2_k127_6726490_6 Probable molybdopterin binding domain K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 303.0
HKD2_k127_6726490_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001711 279.0
HKD2_k127_6726490_8 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004678 273.0
HKD2_k127_6726490_9 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0005575,GO:0005576,GO:0008150,GO:0009605,GO:0009607,GO:0031347,GO:0031348,GO:0035821,GO:0040007,GO:0043207,GO:0044003,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0075136,GO:0080134 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000531 257.0
HKD2_k127_673166_0 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000000000000000000000002448 197.0
HKD2_k127_673166_1 - - - - 0.000000000000000000000000000000000000000000002299 171.0
HKD2_k127_673166_2 DNA primase, small subunit - - - 0.0000000000000000000000000000000009409 130.0
HKD2_k127_673166_3 Cupredoxin-like domain - - - 0.00000000000000006323 81.0
HKD2_k127_6733365_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 7.785e-241 749.0
HKD2_k127_6733365_1 SUF system FeS assembly protein K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002519 249.0
HKD2_k127_6733365_2 - - - - 0.0000000000000000000000000000005055 122.0
HKD2_k127_6733365_3 Protein of unknown function (DUF2505) - - - 0.0000000000000000000001197 97.0
HKD2_k127_6733365_4 helix_turn_helix, Lux Regulon - - - 0.00000000116 61.0
HKD2_k127_6734164_0 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.000000000000000000000000000000000001176 149.0
HKD2_k127_6734164_1 Belongs to the heme-copper respiratory oxidase family K15862 - 1.9.3.1 0.00000000000000000000000000000007888 128.0
HKD2_k127_6734164_2 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 0.00000000000000000000000000001231 122.0
HKD2_k127_6734164_3 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.0000264 51.0
HKD2_k127_6734417_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 2.119e-297 920.0
HKD2_k127_6734417_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 520.0
HKD2_k127_6734417_2 Methyltransferase K00564 - 2.1.1.172 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 306.0
HKD2_k127_6734417_3 HELICc2 K03722 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003556 278.0
HKD2_k127_6766023_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 460.0
HKD2_k127_6766023_1 tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 317.0
HKD2_k127_6796244_0 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000001448 99.0
HKD2_k127_6796244_1 required for the transposition of insertion element IS2404 - - - 0.000005682 48.0
HKD2_k127_6796356_0 ATP-grasp domain - - - 2.842e-300 926.0
HKD2_k127_6796356_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 429.0
HKD2_k127_6796524_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 371.0
HKD2_k127_6796524_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 305.0
HKD2_k127_6796524_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 0.000000000000000000000000000000000000000000007447 162.0
HKD2_k127_6796524_3 - - - - 0.0000000000000000000000000000008269 122.0
HKD2_k127_6796978_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 5.721e-198 626.0
HKD2_k127_6796978_1 shikimate dehydrogenase K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000184 226.0
HKD2_k127_680377_0 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 412.0
HKD2_k127_680377_1 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 318.0
HKD2_k127_680377_2 deoxyribodipyrimidine K06876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 317.0
HKD2_k127_680377_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 287.0
HKD2_k127_6806193_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 462.0
HKD2_k127_6806193_1 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 435.0
HKD2_k127_6806193_2 Histidine kinase K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000000000003079 175.0
HKD2_k127_6806193_3 - - - - 0.0000000000000000000000000000000000000000000007072 174.0
HKD2_k127_6820097_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 492.0
HKD2_k127_6820097_1 EamA-like transporter family K15268 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 426.0
HKD2_k127_6820097_2 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 345.0
HKD2_k127_6820097_4 - - - - 0.000000000000000000000000000000000000002944 154.0
HKD2_k127_6838756_0 Belongs to the UPF0246 family K09861 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 440.0
HKD2_k127_6838756_1 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 422.0
HKD2_k127_6838756_2 - - - - 0.0000000000000000000000000000006386 126.0
HKD2_k127_6864383_0 amino acid K03294 - - 2.383e-244 756.0
HKD2_k127_6864811_0 carboxylase K01969 - 6.4.1.4 1.353e-195 618.0
HKD2_k127_6864811_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000645 234.0
HKD2_k127_6865012_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K01534,K12954,K17686 - 3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54 3.92e-249 775.0
HKD2_k127_6865012_1 fatty acid desaturase K00508 - 1.14.19.3 2.074e-223 693.0
HKD2_k127_6870335_0 PFAM integrase - - - 0.0000000000000000000000000000000000000000009478 167.0
HKD2_k127_6870335_1 COG4584 Transposase and inactivated derivatives - - - 0.00000000001749 73.0
HKD2_k127_6877883_0 Stealth protein CR3, conserved region 3 K01784 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 5.1.3.2 4.533e-317 974.0
HKD2_k127_6877883_1 phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 516.0
HKD2_k127_6877883_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006198,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0008199,GO:0008663,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009187,GO:0009214,GO:0009259,GO:0009261,GO:0009405,GO:0009987,GO:0016043,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042301,GO:0042545,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0045229,GO:0046058,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051704,GO:0055086,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.4.53 0.000000000000000000000000000000001653 130.0
HKD2_k127_6877883_3 Transcription regulator of the Arc MetJ class - - - 0.0000000000006381 68.0
HKD2_k127_6905740_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 9.015e-219 683.0
HKD2_k127_6905740_1 Carbohydrate kinase - - - 3.846e-209 660.0
HKD2_k127_6905740_2 family 4 K01222 - 3.2.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 331.0
HKD2_k127_6905740_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002194 260.0
HKD2_k127_6913370_0 glyoxalase bleomycin resistance protein dioxygenase K06996 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 385.0
HKD2_k127_6913370_1 Protein of unknown function (DUF3073) - - - 0.00000000000000000000000000000000000009389 143.0
HKD2_k127_6913370_2 - - - - 0.00000000000000000000000000000002437 135.0
HKD2_k127_6913370_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000001647 91.0
HKD2_k127_6926370_0 Protein of unknown function (DUF3159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 376.0
HKD2_k127_6926370_1 Protein of unknown function (DUF3710) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 364.0
HKD2_k127_6926370_2 Putative NAD(P)-binding K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000377 264.0
HKD2_k127_6926370_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000002283 272.0
HKD2_k127_6926370_4 Protein of unknown function (DUF3093) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004978 243.0
HKD2_k127_6926370_5 Domain of unknown function (DUF4193) - - - 0.000000000000000000000000000000000000000000000000000009984 192.0
HKD2_k127_6926370_6 Protein of unknown function (DUF3071) - GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000005283 190.0
HKD2_k127_6926370_7 ATP-dependent DNA helicase activity K03655 - 3.6.4.12 0.0000000000000000000000000000000000001337 152.0
HKD2_k127_694681_0 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 346.0
HKD2_k127_694681_1 tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 306.0
HKD2_k127_6988603_0 Pyridoxal-dependent decarboxylase conserved domain K01580 - 4.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 486.0
HKD2_k127_6988603_1 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 325.0
HKD2_k127_6988603_2 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000003141 205.0
HKD2_k127_7001610_0 Belongs to the GARS family K01945,K11788 GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 9.769e-248 768.0
HKD2_k127_7001610_1 Helix-turn-helix XRE-family like proteins - - - 8.961e-232 722.0
HKD2_k127_7001610_2 Oxidoreductase molybdopterin binding - - - 1.046e-204 643.0
HKD2_k127_7001610_3 Belongs to the SAICAR synthetase family K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 561.0
HKD2_k127_7001610_4 ABC transporter K06147 - - 0.000000000000000000000000000184 116.0
HKD2_k127_7001610_6 DNA integration - - - 0.00001065 52.0
HKD2_k127_7001800_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.0 1289.0
HKD2_k127_7001800_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 4.728e-209 653.0
HKD2_k127_7001800_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 596.0
HKD2_k127_7001800_3 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 511.0
HKD2_k127_7001800_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 402.0
HKD2_k127_7001800_5 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 293.0
HKD2_k127_7001800_6 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000003186 214.0
HKD2_k127_7001800_7 ABC transporter K01990 - - 0.000000000000000000000000000001501 124.0
HKD2_k127_7006026_0 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.0000000000000000000000000000000000000000000000004094 194.0
HKD2_k127_700906_0 glutamine amidotransferase K07009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 368.0
HKD2_k127_700906_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 321.0
HKD2_k127_700906_2 Acetyltransferase (GNAT) domain K03829 - - 0.000000000000000000000000000000000000000000000000000000001008 205.0
HKD2_k127_7023863_0 Glycoside hydrolase family 5 K01179,K20628 - 3.2.1.4 1.162e-249 788.0
HKD2_k127_7023863_1 Domain of Unknown Function (DUF1206) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 417.0
HKD2_k127_7023863_2 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000000005291 94.0
HKD2_k127_7023863_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000009888 59.0
HKD2_k127_7049282_0 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 542.0
HKD2_k127_7049282_1 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.00000000000000000000000002692 111.0
HKD2_k127_7071905_0 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.2.1.9 6.931e-238 741.0
HKD2_k127_7091207_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 1.121e-226 708.0
HKD2_k127_7091207_1 Adenylosuccinate lyase C-terminus K01857 - 5.5.1.2 1.131e-197 625.0
HKD2_k127_7091207_2 Serine aminopeptidase, S33 K01055,K14727 - 3.1.1.24,4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 455.0
HKD2_k127_7091207_3 Carboxymuconolactone decarboxylase family K01607,K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000002491 262.0
HKD2_k127_7091207_4 CoA-transferase K01031 - 2.8.3.6 0.0000000000000000000000000000003936 122.0
HKD2_k127_7098791_0 Flagellar basal body rod protein K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 575.0
HKD2_k127_7098791_1 MotA TolQ ExbB proton channel K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 435.0
HKD2_k127_7098791_2 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 424.0
HKD2_k127_7098791_3 Flagellar hook capping protein K02389 - - 0.000000000000000000000000000000000000000000000000000000005139 202.0
HKD2_k127_7098791_4 Flagellar hook-length control protein K02414 - - 0.000000000000000000000000000000000000000000000000000003141 203.0
HKD2_k127_7098791_5 PFAM flagellar FlbD family protein K02385 - - 0.00000000000000000000000000000000000000001184 158.0
HKD2_k127_7098791_6 flagellar motor switch protein K02416 - - 0.00000000000000001377 83.0
HKD2_k127_7108133_0 Serine threonine protein kinase - - - 1.343e-210 663.0
HKD2_k127_7108133_1 PucR C-terminal helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006792 252.0
HKD2_k127_7108133_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000000000000000000000000000000003897 151.0
HKD2_k127_7120995_0 ferric reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 599.0
HKD2_k127_7120995_1 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000004855 87.0
HKD2_k127_7145796_0 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 1.253e-247 785.0
HKD2_k127_7145796_1 N-terminal domain of reverse transcriptase K00986 - 2.7.7.49 0.000000000000000000000000002373 114.0
HKD2_k127_7145796_2 N-terminal domain of reverse transcriptase K00986 - 2.7.7.49 0.000000000000000000000000009044 126.0
HKD2_k127_7148168_0 PFAM Carboxylesterase K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 520.0
HKD2_k127_7148168_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 334.0
HKD2_k127_7265084_0 Peptidase family M3 K01284 - 3.4.15.5 8.622e-312 957.0
HKD2_k127_7265084_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.0000000000000000000000179 99.0
HKD2_k127_7277685_0 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 344.0
HKD2_k127_7277685_1 COG4665 TRAP-type mannitol chloroaromatic compound transport system small permease component - - - 0.00000000000000000000000000002173 126.0
HKD2_k127_7280283_0 PFAM NLP P60 protein K20742,K21471 - 3.4.14.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 312.0
HKD2_k127_7280283_1 - K02413 - - 0.0000000000000000000000000000000000000000000000000001751 190.0
HKD2_k127_7280283_2 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 0.00000000002032 64.0
HKD2_k127_7289732_0 Sulfurtransferase K01011 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 589.0
HKD2_k127_7289732_1 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006294 270.0
HKD2_k127_7289732_2 Fe-S metabolism associated domain K02426 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006132 239.0
HKD2_k127_7289732_3 AFG1-like ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000002178 203.0
HKD2_k127_7307842_0 Flagellar motor switch protein FliN K02417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 413.0
HKD2_k127_7307842_1 flagellar motor switch protein K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004352 262.0
HKD2_k127_7307842_2 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004593 273.0
HKD2_k127_7307842_3 Flagellar biosynthesis protein, FliO K02418 - - 0.0000000000000000000000000000000000000000000000000000004475 198.0
HKD2_k127_7348815_0 DNA polymerase Ligase (LigD) K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0 1069.0
HKD2_k127_7348815_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 480.0
HKD2_k127_7348815_2 Rho termination factor - - - 0.0000000000000000000000000000000000000000003159 164.0
HKD2_k127_7353212_0 PFAM Uncharacterised protein family (UPF0236) - - - 5.43e-215 676.0
HKD2_k127_7353212_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000005874 117.0
HKD2_k127_73716_0 peptidase M13 K01389,K01415,K07386 - 3.4.24.11,3.4.24.71 0.0 1120.0
HKD2_k127_73716_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 0.0 1108.0
HKD2_k127_73716_2 cell envelope-related transcriptional attenuator - - - 4.372e-247 773.0
HKD2_k127_73716_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 506.0
HKD2_k127_73716_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K14215,K21273 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 504.0
HKD2_k127_73716_5 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 465.0
HKD2_k127_73716_6 Alpha beta hydrolase - - - 0.00000000000000000000001498 100.0
HKD2_k127_7372733_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 5.586e-237 736.0
HKD2_k127_7372733_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001051 266.0
HKD2_k127_7372733_2 FOG Transposase - - - 0.0000000000000000000000000000000004234 136.0
HKD2_k127_7372733_3 Helix-turn-helix domain - - - 0.000000000000000003918 88.0
HKD2_k127_7390684_0 Uncharacterized ACR, COG1399 K07040 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 339.0
HKD2_k127_7390684_1 Enoyl-(Acyl carrier protein) reductase K07124,K15734 - 1.1.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 333.0
HKD2_k127_7390684_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 287.0
HKD2_k127_743408_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.4.11.1 2.177e-220 695.0
HKD2_k127_743408_1 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 382.0
HKD2_k127_743408_2 PAC2 family - - - 0.00000000000000000000000000000000000006111 145.0
HKD2_k127_7499648_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 5.472e-208 659.0
HKD2_k127_7499648_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 318.0
HKD2_k127_7499648_2 POTRA domain, FtsQ-type K03589 - - 0.0000000000000004936 87.0
HKD2_k127_7544466_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 4.616e-312 963.0
HKD2_k127_7544466_1 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 1.075e-207 651.0
HKD2_k127_7544466_2 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 294.0
HKD2_k127_7544466_3 Belongs to the peptidase M50B family - - - 0.000000006668 57.0
HKD2_k127_7566827_0 Transposase IS66 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 436.0
HKD2_k127_7580194_0 Belongs to the SEDS family K02563,K03588 GO:0008150,GO:0040007 2.4.1.227 4.31e-235 737.0
HKD2_k127_7580194_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 467.0
HKD2_k127_7580194_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K01924,K02563 - 2.4.1.227,6.3.2.8 0.0000000000000000000000000000000005435 137.0
HKD2_k127_7597_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1234.0
HKD2_k127_7597_1 penicillin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 389.0
HKD2_k127_7604706_0 Glycoside hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 488.0
HKD2_k127_7604706_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 429.0
HKD2_k127_7604706_2 Uncharacterized conserved protein (DUF2183) - - - 0.000000000000000000000000000000000000000000006053 168.0
HKD2_k127_7641746_0 Rhodopirellula transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 422.0
HKD2_k127_7641746_1 Rhodopirellula transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 331.0
HKD2_k127_7666680_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.794e-233 724.0
HKD2_k127_7666680_2 ATP-dependent DNA helicase K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005067 271.0
HKD2_k127_7666680_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000002009 267.0
HKD2_k127_7666686_0 ERAP1-like C-terminal domain K01256,K08776 - 3.4.11.2 0.0 1293.0
HKD2_k127_7672453_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 600.0
HKD2_k127_7672453_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 457.0
HKD2_k127_767991_0 N-terminal of TM subunit in PBP-dependent ABC transporters K15771 - - 1.058e-295 913.0
HKD2_k127_767991_1 ABC transporter substrate-binding protein K15770 - - 0.00000000000000000000000000000000000000000000000000000000000000000000414 235.0
HKD2_k127_767991_2 ABC transporter K15772 - - 0.00000000006195 74.0
HKD2_k127_7681128_0 Aminotransferase class-V - - - 1.277e-254 791.0
HKD2_k127_7681128_1 Natural resistance-associated macrophage protein K03322 GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0030001,GO:0034220,GO:0034755,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071421,GO:0071577,GO:0071578,GO:0072511,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098739,GO:0099587 - 1.543e-204 644.0
HKD2_k127_7681128_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 415.0
HKD2_k127_7681128_3 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000007414 226.0
HKD2_k127_7682298_0 GntP family permease K03299 - - 3.695e-263 814.0
HKD2_k127_7682298_1 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 525.0
HKD2_k127_7682298_10 Diacylglycerol kinase catalytic domain K07029 GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 0.000000000000000009902 96.0
HKD2_k127_7682298_2 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 465.0
HKD2_k127_7682298_3 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 453.0
HKD2_k127_7682298_4 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 464.0
HKD2_k127_7682298_5 Anti-sigma-K factor rskA - GO:0000988,GO:0000989,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006417,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010608,GO:0016020,GO:0016989,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0032268,GO:0034248,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 370.0
HKD2_k127_7682298_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 345.0
HKD2_k127_7682298_7 TIGRFAM carbohydrate kinase, thermoresistant glucokinase family K00851,K00891 - 2.7.1.12,2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 302.0
HKD2_k127_7682298_8 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 289.0
HKD2_k127_7682298_9 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003416 245.0
HKD2_k127_7691178_0 PFAM Carboxylesterase K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 389.0
HKD2_k127_7691178_1 Protein of unknown function (DUF429) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 371.0
HKD2_k127_7694140_0 Thermolysin metallopeptidase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 567.0
HKD2_k127_7694140_1 Transcriptional regulator, AraC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 558.0
HKD2_k127_7694140_2 - - - - 0.000000000000000000000000000000001971 132.0
HKD2_k127_7694140_4 cation diffusion facilitator family transporter - - - 0.00000000003327 75.0
HKD2_k127_7698420_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007582 277.0
HKD2_k127_7698420_1 Belongs to the peptidase S24 family K03503 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002265 259.0
HKD2_k127_7698420_2 Domain of unknown function (DUF4113) K03502 - - 0.0000000000000000000000004343 104.0
HKD2_k127_7703695_0 transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 437.0
HKD2_k127_7703695_1 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 387.0
HKD2_k127_7703695_2 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 347.0
HKD2_k127_7703695_3 Bifunctional nuclease K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 326.0
HKD2_k127_7703695_4 Forkhead associated domain - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006697 276.0
HKD2_k127_7703695_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004306 250.0
HKD2_k127_7733683_0 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 529.0
HKD2_k127_7733683_1 methylmalonate-semialdehyde dehydrogenase K00140 GO:0000166,GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0006066,GO:0006067,GO:0006069,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0022900,GO:0031974,GO:0034308,GO:0036094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070013,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901615 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 402.0
HKD2_k127_7733683_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 376.0
HKD2_k127_7741370_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 338.0
HKD2_k127_7741370_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007872 247.0
HKD2_k127_7741370_2 ABC transporter substrate-binding protein K02051 - - 0.00000000000000000000000003413 110.0
HKD2_k127_7744072_0 Protein tyrosine kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0 1043.0
HKD2_k127_7744072_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 6.597e-199 624.0
HKD2_k127_7744072_2 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 612.0
HKD2_k127_7744072_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 392.0
HKD2_k127_7744072_4 transcriptional regulator - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010565,GO:0016310,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000004052 211.0
HKD2_k127_7744072_5 - - - - 0.00000000000000000000000000000000000000000000000000006612 192.0
HKD2_k127_7744072_6 Belongs to the class-II DAHP synthase family K01626,K16019 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0022607,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.5.1.54 0.000000000000000000000044 98.0
HKD2_k127_7744506_0 Major Facilitator Superfamily K08167 - - 5.565e-241 754.0
HKD2_k127_7744506_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 424.0
HKD2_k127_7744506_2 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001945 276.0
HKD2_k127_7744506_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 266.0
HKD2_k127_7744506_5 tetR family - - - 0.00000000000000000000000000000000000000000000000000000000001176 208.0
HKD2_k127_7744506_6 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000000000000000000001002 127.0
HKD2_k127_7768897_0 cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 396.0
HKD2_k127_7768897_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 0.00000000000000003524 81.0
HKD2_k127_7774861_0 Aminomethyltransferase folate-binding domain - - - 2.912e-276 853.0
HKD2_k127_7774861_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 509.0
HKD2_k127_7774861_2 transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 305.0
HKD2_k127_7774861_3 ABC-type branched-chain amino acid transport - - - 0.0000000000000000000000000000000000005231 140.0
HKD2_k127_7774861_4 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000001563 139.0
HKD2_k127_7775331_0 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 524.0
HKD2_k127_7775331_1 Uncharacterized conserved protein (DUF2183) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 499.0
HKD2_k127_7777282_0 Phage integrase family protein - - - 7.523e-286 895.0
HKD2_k127_7777282_1 - - - - 0.000000000000000000000000000003053 125.0
HKD2_k127_7777282_2 Transposase DDE domain - - - 0.0000000000000000000002716 100.0
HKD2_k127_7786076_0 A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics K18455 GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657 3.5.1.115 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 556.0
HKD2_k127_7786076_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 330.0
HKD2_k127_7786076_2 membrane protein (homolog of Drosophila rhomboid) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 296.0
HKD2_k127_7786076_3 Domain of unknown function (DUF4307) - - - 0.0000000000000000000000000000000000000000000000000000000000001033 216.0
HKD2_k127_7786076_4 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000001858 203.0
HKD2_k127_7786076_5 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000001688 160.0
HKD2_k127_7786076_6 - - - - 0.00000000000000000000000001214 114.0
HKD2_k127_7790137_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 565.0
HKD2_k127_7790137_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 391.0
HKD2_k127_7790137_2 Superfamily I DNA and RNA helicases and helicase subunits - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008848 303.0
HKD2_k127_7790137_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 291.0
HKD2_k127_7790137_4 SAF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
HKD2_k127_7790137_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000124 248.0
HKD2_k127_7790137_6 regulatory protein, FmdB family - - - 0.00000000000000000000000000000000000002003 144.0
HKD2_k127_7790312_0 MMPL family K06994 - - 0.0 1395.0
HKD2_k127_7790312_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11103 - - 5.684e-260 806.0
HKD2_k127_7790312_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 316.0
HKD2_k127_7790312_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000003411 216.0
HKD2_k127_7790312_4 Putative heavy-metal-binding - - - 0.000000000000000000000000000000000000000000000000000000001677 201.0
HKD2_k127_7790312_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000004255 200.0
HKD2_k127_7790312_6 - - - - 0.000000000000000000000000000000000000000001024 162.0
HKD2_k127_7790312_7 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000009988 127.0
HKD2_k127_7790423_0 DNA polymerase K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 383.0
HKD2_k127_7790423_1 bacterial-type flagellum organization - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 373.0
HKD2_k127_7792620_0 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 434.0
HKD2_k127_7792620_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 395.0
HKD2_k127_7792620_2 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000000000002474 132.0
HKD2_k127_7803714_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.0 1143.0
HKD2_k127_7803714_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000006363 156.0
HKD2_k127_7809110_0 cystathionine gamma-synthase K01739,K01758 - 2.5.1.48,4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 429.0
HKD2_k127_7809110_1 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 310.0
HKD2_k127_7809110_2 Protein of unknown function (DUF2516) - - - 0.000000000000000000000000000000000000000000000000000000004255 200.0
HKD2_k127_7834468_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 327.0
HKD2_k127_7834468_1 Response regulators are key elements in two-component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 300.0
HKD2_k127_7834468_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009334 259.0
HKD2_k127_7834468_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000007604 192.0
HKD2_k127_7835492_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.865e-277 854.0
HKD2_k127_7835492_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 332.0
HKD2_k127_7835492_2 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000004426 233.0
HKD2_k127_7838446_0 The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.80,2.8.1.11 6.659e-226 703.0
HKD2_k127_7838446_1 tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 397.0
HKD2_k127_7838446_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000001821 204.0
HKD2_k127_7838446_3 - - - - 0.000000000000000000000000000000000000000002856 158.0
HKD2_k127_7838446_4 Protein of unknown function (DUF3107) - - - 0.0000000000000000000000000000004147 124.0
HKD2_k127_7838446_5 Short-chain dehydrogenase reductase sdr - - - 0.000000000006645 70.0
HKD2_k127_7846587_0 Amidohydrolase family K01464,K01465,K01466 - 3.5.2.2,3.5.2.3,3.5.2.5 4.389e-223 698.0
HKD2_k127_7846587_1 FAD binding domain K00244 - 1.3.5.4 1.561e-204 647.0
HKD2_k127_7846587_2 Bacterial transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 374.0
HKD2_k127_7846587_3 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 329.0
HKD2_k127_7846587_4 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001433 256.0
HKD2_k127_7852545_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0 1000.0
HKD2_k127_7852545_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 597.0
HKD2_k127_7852545_2 Belongs to the MIP aquaporin (TC 1.A.8) family K02440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 474.0
HKD2_k127_7852545_3 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 371.0
HKD2_k127_7854027_0 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 574.0
HKD2_k127_7854027_1 2-methylcitrate dehydratase K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 475.0
HKD2_k127_7854027_2 Belongs to the citrate synthase family K01647,K01659 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0071704 2.3.3.1,2.3.3.5 0.00000000000000000000002922 100.0
HKD2_k127_7860533_0 Rhodopirellula transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 513.0
HKD2_k127_7860533_1 Helicase conserved C-terminal domain - - - 0.0000000009836 59.0
HKD2_k127_7863039_0 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.0 1151.0
HKD2_k127_7863039_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 1.095e-224 708.0
HKD2_k127_7863039_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 507.0
HKD2_k127_7863039_3 Helix-turn-helix diphteria tox regulatory element K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 437.0
HKD2_k127_7863039_4 peptidase K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 405.0
HKD2_k127_7863039_5 cysteine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 377.0
HKD2_k127_7863039_6 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 338.0
HKD2_k127_7863039_7 MobA-like NTP transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003844 240.0
HKD2_k127_7863039_8 molybdenum cofactor guanylyltransferase activity K03752 - 2.7.7.77 0.000000000000000000000000000000000000007748 153.0
HKD2_k127_7863039_9 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.00009822 47.0
HKD2_k127_7864260_0 helicase K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 361.0
HKD2_k127_7864260_1 - - GO:0008150,GO:0010941,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044531,GO:0044532,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0060548,GO:0065007 - 0.00000000000000000000000000000000001786 140.0
HKD2_k127_7864260_2 TIGRFAM helicase secretion neighborhood TadE-like protein - - - 0.0000000000000000000000004124 114.0
HKD2_k127_7869139_0 transposase activity - - - 0.0000000000000000000000000003017 126.0
HKD2_k127_7869139_1 transposase activity - - - 0.00003156 56.0
HKD2_k127_7870011_0 DivIVA protein - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 340.0
HKD2_k127_7870011_1 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 319.0
HKD2_k127_7870011_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 322.0
HKD2_k127_7870011_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 305.0
HKD2_k127_7870011_4 Multi-copper polyphenol oxidoreductase laccase K05810 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 302.0
HKD2_k127_7870011_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000003727 162.0
HKD2_k127_7870011_6 YGGT family K02221 - - 0.0000000000000000000000000000000000000001062 152.0
HKD2_k127_7870011_7 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000001318 79.0
HKD2_k127_7875867_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 599.0
HKD2_k127_7875867_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004 247.0
HKD2_k127_7876050_0 IMP dehydrogenase family protein K00088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 496.0
HKD2_k127_7876050_1 ABC transporter K06147,K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 470.0
HKD2_k127_7876050_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 311.0
HKD2_k127_7876050_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001576 271.0
HKD2_k127_7884546_0 methylmalonate-semialdehyde dehydrogenase K00140 GO:0000166,GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0006066,GO:0006067,GO:0006069,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0022900,GO:0031974,GO:0034308,GO:0036094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070013,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901615 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 582.0
HKD2_k127_7884546_1 enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 531.0
HKD2_k127_7884546_2 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 500.0
HKD2_k127_7884546_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 453.0
HKD2_k127_7884546_4 Identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds - - - 0.000000000001341 68.0
HKD2_k127_7901176_0 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 5.499e-262 823.0
HKD2_k127_7901176_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 428.0
HKD2_k127_7901176_2 RNA-directed DNA polymerase (reverse transcriptase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000001294 192.0
HKD2_k127_7901176_3 - - - - 0.00000000000000000000000000000000002716 139.0
HKD2_k127_7909910_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0 1090.0
HKD2_k127_7909910_1 Ribosomal protein S1 K02945 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 3.375e-308 946.0
HKD2_k127_7909910_2 Sterol carrier protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 572.0
HKD2_k127_7909910_3 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000000000000000000004157 211.0
HKD2_k127_7925338_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000003483 237.0
HKD2_k127_7925338_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000037 229.0
HKD2_k127_7925338_2 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000002267 78.0
HKD2_k127_7936051_0 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 505.0
HKD2_k127_7936051_1 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 347.0
HKD2_k127_7937591_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000006173 111.0
HKD2_k127_7937591_1 - - - - 0.000000001042 68.0
HKD2_k127_7951676_0 PFAM MULE transposase, conserved domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 391.0
HKD2_k127_7951676_1 - - - - 0.00000000000000000000000000000000000000000000000000000000502 207.0
HKD2_k127_7951676_2 Homeodomain-like domain - - - 0.000000004619 57.0
HKD2_k127_7960830_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 460.0
HKD2_k127_7960830_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000003178 234.0
HKD2_k127_7960830_2 Glycosyl transferase family 2 - - - 0.00005303 47.0
HKD2_k127_7969511_0 Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 570.0
HKD2_k127_7969511_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 315.0
HKD2_k127_7969511_2 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009165 295.0
HKD2_k127_7969511_3 Signal transduction histidine kinase regulating citrate malate metabolism K02476 - 2.7.13.3 0.00000000000000000000000000000000000000000000002891 173.0
HKD2_k127_8018412_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1266.0
HKD2_k127_8018412_1 CobQ/CobB/MinD/ParA nucleotide binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002089 259.0
HKD2_k127_8020238_0 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 533.0
HKD2_k127_8020238_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 495.0
HKD2_k127_8020468_0 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 391.0
HKD2_k127_8020468_1 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000001777 56.0
HKD2_k127_8031991_0 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 1.324e-202 654.0
HKD2_k127_8031991_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00367,K00372,K03885 - 1.6.99.3,1.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 435.0
HKD2_k127_8031991_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 395.0
HKD2_k127_8031991_3 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303 - 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 367.0
HKD2_k127_8031991_4 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000004603 215.0
HKD2_k127_8031991_5 membrane-bound metal-dependent hydrolase - - - 0.000000000000000000000000000000000209 132.0
HKD2_k127_8031991_6 - - - - 0.000000000000000000000000000323 117.0
HKD2_k127_8034580_0 drug resistance transporter, EmrB QacA subfamily - - - 0.0 1056.0
HKD2_k127_8034580_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0 1052.0
HKD2_k127_8034580_2 ABC transporter K06147 - - 9.579e-292 899.0
HKD2_k127_8034580_3 Belongs to the arginase family K01480 - 3.5.3.11 8.911e-217 674.0
HKD2_k127_8034580_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004425 247.0
HKD2_k127_8040366_0 Pyridine nucleotide-disulphide oxidoreductase - - - 5.129e-222 705.0
HKD2_k127_8040366_1 Sodium Bile acid symporter family K03325 - - 6.685e-206 644.0
HKD2_k127_8040366_2 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000392 250.0
HKD2_k127_8040570_0 transposition K07497 - - 0.0000000000000000000000000000000000000000000000000000001554 208.0
HKD2_k127_8040570_1 recombinase XerD K04763 - - 0.000000004584 62.0
HKD2_k127_8058497_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 538.0
HKD2_k127_8058497_1 oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 469.0
HKD2_k127_8058497_2 Anti-sigma-K factor rskA - - - 0.0000000000000000000000000000000000000000000000000000000000000007705 229.0
HKD2_k127_8058497_3 arsR family K03892 - - 0.0000000000000000000000000000000000000000004926 158.0
HKD2_k127_8058497_4 - - - - 0.0000000000001901 72.0
HKD2_k127_8078549_0 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 526.0
HKD2_k127_8078549_1 Strong inhibitor of bacterial serine proteases such as subtilisin - - - 0.0000000000000000000000000000000000000000000000000000001825 200.0
HKD2_k127_8088578_0 Sugar (and other) transporter K08172 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 547.0
HKD2_k127_8088578_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001541 267.0
HKD2_k127_8088578_2 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.0000000000000000000000000000000000007848 158.0
HKD2_k127_8092337_0 PFAM Band 7 protein - - - 2.669e-245 767.0
HKD2_k127_8092337_1 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 520.0
HKD2_k127_8092337_2 Domain of unknown function (DUF4383) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009118 273.0
HKD2_k127_8092337_3 - - - - 0.0000000000000000000000000000505 116.0
HKD2_k127_8096926_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 503.0
HKD2_k127_8096926_1 Intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 336.0
HKD2_k127_8096926_2 Protein of unknown function (DUF2630) - - - 0.000000000000000000000000000006624 122.0
HKD2_k127_8118563_0 DEAD DEAH box helicase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 593.0
HKD2_k127_8126015_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 507.0
HKD2_k127_8126015_2 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000000000000000001343 146.0
HKD2_k127_8128871_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 2.929e-215 669.0
HKD2_k127_8128871_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 566.0
HKD2_k127_8128871_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 445.0
HKD2_k127_8128871_3 helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001992 267.0
HKD2_k127_8128871_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001135 246.0
HKD2_k127_8128871_5 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000001489 226.0
HKD2_k127_8128871_6 Protein of unknown function (DUF3046) - - - 0.00000000000000000000000000000000000007627 142.0
HKD2_k127_8128871_7 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000001437 142.0
HKD2_k127_8128871_8 Helix-turn-helix domain protein - - - 0.000000000000000000000000000000005006 130.0
HKD2_k127_8132332_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.3.14 0.0 1085.0
HKD2_k127_8132332_1 CoA-binding domain K01710 - 4.2.1.46 0.0 1080.0
HKD2_k127_8132332_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000003054 132.0
HKD2_k127_8132332_11 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000002644 90.0
HKD2_k127_8132332_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 537.0
HKD2_k127_8132332_3 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 533.0
HKD2_k127_8132332_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 486.0
HKD2_k127_8132332_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 438.0
HKD2_k127_8132332_6 Glycosyl transferase family 2 K16649 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008378,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016757,GO:0016758,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.4.1.287 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 361.0
HKD2_k127_8132332_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 284.0
HKD2_k127_8132332_8 - K02116 - - 0.00000000000000000000000000000000000000000000000000000000000000000004932 238.0
HKD2_k127_8132332_9 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex - - - 0.00000000000000000000000000000000000000000005637 164.0
HKD2_k127_8140546_0 PFAM Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 309.0
HKD2_k127_8140546_1 Transposase DDE domain - - - 0.00000000000000000000000000000000000000001054 156.0
HKD2_k127_8140546_2 IMG reference gene - - - 0.000000000000003276 79.0
HKD2_k127_8156475_0 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 5.182e-301 929.0
HKD2_k127_8156475_1 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000005683 143.0
HKD2_k127_8159843_0 Protein of unknown function (DUF979) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 557.0
HKD2_k127_8159843_1 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 494.0
HKD2_k127_8159843_2 Protein of unknown function (DUF969) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 403.0
HKD2_k127_8159843_3 gntR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 339.0
HKD2_k127_81838_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1154.0
HKD2_k127_81838_1 Domain of unknown function (DUF4118) K07646 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 2.7.13.3 8.079e-236 734.0
HKD2_k127_81838_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005072 274.0
HKD2_k127_81838_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000006895 220.0
HKD2_k127_8232921_0 - K14337,K14339 - - 1.124e-301 932.0
HKD2_k127_8232921_1 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 374.0
HKD2_k127_8232921_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000001047 162.0
HKD2_k127_8232921_3 DNA alkylation repair - - - 0.000000000000000000000000000000002308 130.0
HKD2_k127_8259125_0 Putative nucleotide-binding of sugar-metabolising enzyme K22129 - 2.7.1.219,2.7.1.220 0.000000000000000000000000000000000000000000003672 179.0
HKD2_k127_8259125_1 Amidohydrolase K07045 - - 0.000000000000000000000000000004527 121.0
HKD2_k127_8267108_0 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 3.222e-262 812.0
HKD2_k127_8267108_1 Penicillin binding protein transpeptidase domain K05364 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000001438 83.0
HKD2_k127_8271778_0 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 512.0
HKD2_k127_8271778_1 Domain of unknown function (DUF4191) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 424.0
HKD2_k127_8271778_2 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002199 269.0
HKD2_k127_8271778_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000008269 177.0
HKD2_k127_8298766_0 TrwC protein - - - 0.0000000000000000005007 101.0
HKD2_k127_8298766_1 Plasmid encoded RepA protein - - - 0.0000000000284 66.0
HKD2_k127_8302501_0 O-acetylhomoserine K01740 - 2.5.1.49 3.684e-272 841.0
HKD2_k127_8302501_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 4.971e-203 642.0
HKD2_k127_8302501_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 284.0
HKD2_k127_8305780_0 NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 557.0
HKD2_k127_8305780_1 Crp Fnr family K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 432.0
HKD2_k127_8305780_2 Colicin V production protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 417.0
HKD2_k127_8305780_3 endoribonuclease L-PSP - - - 0.00000000004922 62.0
HKD2_k127_8330877_0 transposase activity - - - 4.732e-223 700.0
HKD2_k127_8330877_1 best DB hits BLAST gb AAD45539.1 - - - 0.0000000000000000002804 93.0
HKD2_k127_8330877_2 COG2183 Transcriptional accessory protein - - - 0.000000003583 63.0
HKD2_k127_83370_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 358.0
HKD2_k127_83370_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000003012 132.0
HKD2_k127_8339614_0 Protein of unknown function (DUF2004) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 323.0
HKD2_k127_8339614_1 Belongs to the aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 282.0
HKD2_k127_8339614_2 ROK family - - - 0.0000000000000000000000000000000002786 132.0
HKD2_k127_8352453_0 ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001188 287.0
HKD2_k127_8352453_1 - - - - 0.00000001216 64.0
HKD2_k127_8382559_0 Histidine kinase K02484 - 2.7.13.3 1.657e-249 778.0
HKD2_k127_8382559_1 Glycosyl transferase family 2 - - - 3.236e-240 751.0
HKD2_k127_8382559_2 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 290.0
HKD2_k127_8382559_3 response regulator K02483 GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0098771 - 0.000000000000000000000000000000000000000000000000000000000000000002535 226.0
HKD2_k127_8414790_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.404e-291 897.0
HKD2_k127_8414790_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001753 246.0
HKD2_k127_8445438_0 Low molecular weight phosphotyrosine protein phosphatase K01104 GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001438 276.0
HKD2_k127_8445438_1 synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000007208 259.0
HKD2_k127_8445438_2 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001166 233.0
HKD2_k127_8445438_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.000000000000000000000000000000000000000000000000000000000003802 216.0
HKD2_k127_8445438_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000002298 196.0
HKD2_k127_8445438_5 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.00000000000000000000000000000000000000000000000000005626 187.0
HKD2_k127_8480706_0 transferase activity, transferring glycosyl groups K00786 - - 4.986e-219 702.0
HKD2_k127_8480706_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 489.0
HKD2_k127_8480706_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000005274 225.0
HKD2_k127_8480706_3 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000002578 224.0
HKD2_k127_8480706_4 Thiamine-binding protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000001007 170.0
HKD2_k127_8480706_5 - - - - 0.000000000000000001246 97.0
HKD2_k127_8495996_0 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 504.0
HKD2_k127_8495996_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 461.0
HKD2_k127_8495996_2 Domain of Unknown Function (DUF1206) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 373.0
HKD2_k127_8495996_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 296.0
HKD2_k127_8495996_4 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000000008723 209.0
HKD2_k127_8495996_5 protein conserved in bacteria K05375 - - 0.0000000000000000000000000000000000000006944 148.0
HKD2_k127_8495996_6 Peptide synthetase K02364 - 6.3.2.14 0.00000000000000000000000729 102.0
HKD2_k127_8501755_0 Alcohol dehydrogenase GroES-like domain - - - 1.51e-208 651.0
HKD2_k127_8501755_1 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 312.0
HKD2_k127_8501755_2 Major facilitator superfamily - - - 0.0000000000000000000000000004263 113.0
HKD2_k127_8520446_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 1.44e-306 943.0
HKD2_k127_8576807_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 461.0
HKD2_k127_8576807_1 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 414.0
HKD2_k127_8595217_0 PFAM Fibronectin, type III domain - - - 9.714e-222 695.0
HKD2_k127_8595217_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 496.0
HKD2_k127_8616139_0 PFAM Transposase IS3 IS911 K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 302.0
HKD2_k127_8616139_1 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000224 289.0
HKD2_k127_8616139_2 RNA-directed DNA polymerase (reverse transcriptase) - - - 0.000000000000000000000000000000000001571 141.0
HKD2_k127_8639617_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 1.449e-313 962.0
HKD2_k127_8639617_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000009445 119.0
HKD2_k127_86580_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 5.207e-217 687.0
HKD2_k127_86580_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 516.0
HKD2_k127_86580_2 Glycosyltransferase Family 4 K12583 GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000002846 183.0
HKD2_k127_8673602_0 Insertion element 4 transposase N-terminal - - - 0.00000000000000000000000007796 123.0
HKD2_k127_8734896_0 Peptidase S15 K06978 - - 7.526e-292 906.0
HKD2_k127_8734896_1 Major facilitator Superfamily - - - 6.611e-252 783.0
HKD2_k127_8734896_2 transcriptional regulator K02616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 491.0
HKD2_k127_8734896_3 Protein of unknown function (DUF3237) - - - 0.0000000000000000000000000000000000000000000000000000000000000001948 228.0
HKD2_k127_8734896_4 Lysine exporter protein (LysE YggA) K05834 - - 0.00000000000000000000000000000000000000000003919 161.0
HKD2_k127_8742192_0 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 509.0
HKD2_k127_8742192_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000441 257.0
HKD2_k127_8834095_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001759 281.0
HKD2_k127_8834095_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000003427 225.0
HKD2_k127_8834095_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000001118 171.0
HKD2_k127_8836489_0 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000009526 254.0
HKD2_k127_8836489_1 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004928 236.0
HKD2_k127_88427_0 G5 K21688 GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 582.0
HKD2_k127_88427_1 hydrolase, TatD family K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 517.0
HKD2_k127_88427_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 506.0
HKD2_k127_88427_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 309.0
HKD2_k127_88427_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000006271 110.0
HKD2_k127_8880347_0 ATP-dependent helicase HrpA K03578 - 3.6.4.13 1.544e-205 642.0
HKD2_k127_8880347_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009973 329.0
HKD2_k127_894210_0 Histidine kinase - - - 1.613e-205 653.0
HKD2_k127_894210_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 496.0
HKD2_k127_894210_2 Pfam Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002351 279.0
HKD2_k127_8944976_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 436.0
HKD2_k127_8944976_1 NAD(P)H dehydrogenase (quinone) activity K00355,K11748 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 295.0
HKD2_k127_8944976_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 291.0
HKD2_k127_8944976_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000537 234.0
HKD2_k127_8945213_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006045 274.0
HKD2_k127_8945213_1 Transposase - - - 0.000000000000000000000000000000000000000000000000000008425 194.0
HKD2_k127_8945213_2 Transposase - - - 0.000000000000000000000000000000000000000000000228 180.0
HKD2_k127_8945213_3 DDE superfamily endonuclease - - - 0.000000000003905 72.0
HKD2_k127_8945213_4 Transposase (IS116 IS110 IS902 family) K07486 - - 0.00000002157 56.0
HKD2_k127_8947133_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 587.0
HKD2_k127_8947133_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000005741 240.0
HKD2_k127_8947133_2 GCN5-related N-acetyl-transferase K02346,K06975 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000003064 198.0
HKD2_k127_8947133_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000002259 169.0
HKD2_k127_8967775_0 Aminotransferase K00812 - 2.6.1.1 2.583e-243 757.0
HKD2_k127_8967775_1 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 466.0
HKD2_k127_8967775_2 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000001013 163.0
HKD2_k127_8967775_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000001106 144.0
HKD2_k127_8967775_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000002352 128.0
HKD2_k127_8988330_1 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000005578 229.0
HKD2_k127_8988330_2 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000006336 196.0
HKD2_k127_9001498_0 Ammonium Transporter K03320 - - 4.813e-261 806.0
HKD2_k127_9001498_1 Major Facilitator Superfamily - - - 2.718e-212 668.0
HKD2_k127_9001498_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 600.0
HKD2_k127_9003997_0 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 457.0
HKD2_k127_9003997_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000008064 226.0
HKD2_k127_9003997_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000001715 84.0
HKD2_k127_9005205_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0 1020.0
HKD2_k127_9005205_1 Belongs to the GPI family K01810 - 5.3.1.9 1.646e-253 786.0
HKD2_k127_9005205_2 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 580.0
HKD2_k127_9005205_3 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 448.0
HKD2_k127_9005205_4 Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters - - - 0.0007747 43.0
HKD2_k127_9014639_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 0.0 1626.0
HKD2_k127_9015930_0 CBS domain - - - 2.299e-265 818.0
HKD2_k127_9015930_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 342.0
HKD2_k127_9022082_0 L-lactate permease K03303 - - 1.18e-261 817.0
HKD2_k127_9022082_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.674e-208 656.0
HKD2_k127_9022082_2 transcriptional regulator K13641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 402.0
HKD2_k127_9022082_3 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 GO:0000287,GO:0001968,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009117,GO:0009150,GO:0009259,GO:0009436,GO:0009986,GO:0009987,GO:0015936,GO:0015980,GO:0016020,GO:0016054,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019637,GO:0019693,GO:0019752,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0042603,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046810,GO:0046872,GO:0046912,GO:0046983,GO:0048037,GO:0050662,GO:0050840,GO:0051186,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0072350,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 374.0
HKD2_k127_9026592_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 569.0
HKD2_k127_9026592_1 Beta-lactamase superfamily domain - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 526.0
HKD2_k127_9026592_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 484.0
HKD2_k127_9026592_3 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 467.0
HKD2_k127_9026592_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 372.0
HKD2_k127_9026592_5 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 289.0
HKD2_k127_9029444_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 460.0
HKD2_k127_9029444_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 453.0
HKD2_k127_9029444_2 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000001138 154.0
HKD2_k127_9030376_0 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 552.0
HKD2_k127_9030376_1 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 478.0
HKD2_k127_9030376_2 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000006577 206.0
HKD2_k127_9041264_0 polysaccharide deacetylase - - - 1.944e-320 987.0
HKD2_k127_9041264_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 3.034e-265 818.0
HKD2_k127_9041264_2 polysaccharide deacetylase - - - 4.841e-259 810.0
HKD2_k127_9041264_3 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 6.009e-256 804.0
HKD2_k127_9041264_4 universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 492.0
HKD2_k127_9041264_5 RarD protein K05786 - - 0.0000000000000000000000000000000000000000000000000000000001024 205.0
HKD2_k127_9041264_6 Glycosyl transferase family 21 K11936 - - 0.0000000000000000000000000000000000000000000001761 184.0
HKD2_k127_9054620_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 7.756e-278 860.0
HKD2_k127_9054620_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 4.712e-259 804.0
HKD2_k127_9054620_2 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 572.0
HKD2_k127_9054620_3 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009972,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042455,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.5 0.000000000000000000000000000000000000000000000000000000000000000002176 250.0
HKD2_k127_9054620_4 pyrimidine-nucleoside phosphorylase K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 0.00000000000000000000000000000000000001107 153.0
HKD2_k127_9094887_0 ABC transporter - - - 8.132e-289 891.0
HKD2_k127_9094887_1 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000003835 184.0
HKD2_k127_9101108_0 Proton-conducting membrane transporter K05568 - - 4.868e-258 800.0
HKD2_k127_9101108_1 Na+/H+ ion antiporter subunit K05569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 309.0
HKD2_k127_9101108_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000007884 235.0
HKD2_k127_9101108_3 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.0000000000000000000000000000000000000000000000000000000000001385 214.0
HKD2_k127_9101108_4 Protein of unknown function (DUF4235) - - - 0.000000000000000000000000000000000000000002067 156.0
HKD2_k127_9101108_5 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.000000000000000000000000000002587 123.0
HKD2_k127_9102095_0 Amylo-alpha-1,6-glucosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 593.0
HKD2_k127_9102095_1 Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000005233 178.0
HKD2_k127_9120682_0 Protein of unknown function (DUF501) K09009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 384.0
HKD2_k127_9120682_1 Septum formation initiator K13052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006678 246.0
HKD2_k127_9120682_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000009912 142.0
HKD2_k127_9128997_0 Succinate dehydrogenase flavoprotein subunit K00239,K00278 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4,1.4.3.16 3.6e-245 759.0
HKD2_k127_9128997_1 mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 399.0
HKD2_k127_9128997_2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 297.0
HKD2_k127_9128997_3 succinate dehydrogenase K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003292 254.0
HKD2_k127_9135_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 401.0
HKD2_k127_9135_1 DNA polymerase III, subunits gamma and tau K02343 GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000002308 172.0
HKD2_k127_9135_2 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000009743 164.0
HKD2_k127_9139999_0 ABC1 family - - - 1.088e-277 863.0
HKD2_k127_9139999_1 glutamine amidotransferase K07008 - 3.5.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 452.0
HKD2_k127_9139999_2 Glycosyl hydrolases family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 422.0
HKD2_k127_9139999_3 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000000001295 123.0
HKD2_k127_9141973_0 Dihydroxyacetone kinase K05878 - 2.7.1.121 1.9e-199 623.0
HKD2_k127_9141973_1 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 426.0
HKD2_k127_9141973_2 Dak2 K05879 - 2.7.1.121 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 340.0
HKD2_k127_9141973_3 Acetyltransferase (GNAT) domain K00619 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 316.0
HKD2_k127_9141973_4 PTS system fructose IIA component K05881 - 2.7.1.121 0.000000000000000000000000000000000000000000000000005293 186.0
HKD2_k127_9172830_0 PFAM Aminotransferase class I and II K00812,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 2.717e-268 826.0
HKD2_k127_9172830_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 535.0
HKD2_k127_9172830_2 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 500.0
HKD2_k127_9172830_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000000008967 119.0
HKD2_k127_9187131_0 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 344.0
HKD2_k127_9187131_1 - - - - 0.000000000000000000000000000000000000000000000000000002213 201.0
HKD2_k127_9187131_2 NUDIX domain - - - 0.0000000000000000000000000000000000004785 150.0
HKD2_k127_9188618_0 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 523.0
HKD2_k127_9188618_1 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 458.0
HKD2_k127_9188618_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 447.0
HKD2_k127_9188618_3 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 352.0
HKD2_k127_9188618_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 340.0
HKD2_k127_9188618_5 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000138 286.0
HKD2_k127_921829_0 Winged helix-turn helix - - - 0.00006577 52.0
HKD2_k127_921829_1 IMG reference gene - - - 0.00008614 55.0
HKD2_k127_9219432_0 DNA protecting protein DprA K04096 - - 2.464e-194 618.0
HKD2_k127_9219432_1 Magnesium chelatase, subunit ChlI K07391 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000003272 172.0
HKD2_k127_9228341_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1036.0
HKD2_k127_9228341_1 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 471.0
HKD2_k127_9228341_2 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 449.0
HKD2_k127_9228341_3 helix_turn_helix, Arsenical Resistance Operon Repressor K21885 - - 0.00000000000000000000000000000000000000000000001124 172.0
HKD2_k127_9240479_0 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 395.0
HKD2_k127_9240479_1 RarD protein K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 384.0
HKD2_k127_9253010_0 Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 606.0
HKD2_k127_9253010_1 Class III cytochrome C family - - - 0.0000000000000000000001277 100.0
HKD2_k127_9260510_0 May catalyze the transamination reaction in phenylalanine biosynthesis K00817 - 2.6.1.9 6.909e-204 639.0
HKD2_k127_9260510_1 Pyruvate dehydrogenase K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 395.0
HKD2_k127_9260510_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000000000000000000000000000000000000004337 224.0
HKD2_k127_9260512_0 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 4.154e-229 718.0
HKD2_k127_9260512_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 503.0
HKD2_k127_9260512_2 - - - - 0.000000000000000000000000000000000000000000000000000000000004512 212.0
HKD2_k127_926352_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.8 0.0 1395.0
HKD2_k127_926352_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 312.0
HKD2_k127_926352_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000000000000000171 171.0
HKD2_k127_927437_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 571.0
HKD2_k127_927437_1 Tn3 transposase DDE domain - - - 0.00003522 46.0
HKD2_k127_9274711_0 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 451.0
HKD2_k127_9274711_1 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000003633 178.0
HKD2_k127_9274740_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 600.0
HKD2_k127_9274740_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 297.0
HKD2_k127_9311181_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 1.72e-230 722.0
HKD2_k127_9311181_1 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 430.0
HKD2_k127_9340000_0 Glycosyl transferase 4-like K19002 - 2.4.1.337 2.019e-223 696.0
HKD2_k127_9340000_1 acyl-CoA dehydrogenase K00252 - 1.3.8.6 6.747e-217 674.0
HKD2_k127_9340000_2 Magnesium transporter NIPA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 374.0
HKD2_k127_9409613_0 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 546.0
HKD2_k127_9409613_1 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 534.0
HKD2_k127_9409613_2 ABC transporter K02028,K02029 - 3.6.3.21 0.000000000000000000000000000000000000000007344 156.0
HKD2_k127_9450763_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.466e-297 914.0
HKD2_k127_9450763_1 PFAM regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 424.0
HKD2_k127_9450763_2 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 351.0
HKD2_k127_9450763_3 Serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 295.0
HKD2_k127_9452246_0 DNA topoisomerase (ATP-hydrolyzing) K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 477.0
HKD2_k127_9452246_1 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006254 272.0
HKD2_k127_9452246_2 lactoylglutathione lyase activity - - - 0.0000000000000000000003267 96.0
HKD2_k127_9453677_0 cell envelope-related transcriptional attenuator - - - 1.603e-224 707.0
HKD2_k127_9453677_1 Haem-degrading - - - 0.0000000000000004077 78.0
HKD2_k127_9461402_0 E1-E2 ATPase K01533,K01534,K12954,K17686 - 3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 610.0
HKD2_k127_9461402_1 Glycosyl hydrolase family 65 central catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 413.0
HKD2_k127_9461402_2 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 357.0
HKD2_k127_9467260_0 Helicase conserved C-terminal domain - - - 0.0 1268.0
HKD2_k127_9467260_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 464.0
HKD2_k127_9467260_2 helicase K10843 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000002461 262.0
HKD2_k127_9467260_3 Cold shock protein domain K03704 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006264 251.0
HKD2_k127_9467260_4 Protein of unknown function (DUF3027) - - - 0.0000000000000000000000000000000000000000000000000000000000002035 220.0
HKD2_k127_9471468_0 adenosine deaminase K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 432.0
HKD2_k127_9471468_1 MazG nucleotide pyrophosphohydrolase domain K02428,K02499 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 298.0
HKD2_k127_9471468_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006091 278.0
HKD2_k127_949588_0 Belongs to the 5'-nucleotidase family K01081,K01119 - 3.1.3.5,3.1.3.6,3.1.4.16 8.936e-297 922.0
HKD2_k127_949588_1 Acetyltransferase (GNAT) family - - - 1.545e-198 623.0
HKD2_k127_949588_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 326.0
HKD2_k127_949588_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000009456 220.0
HKD2_k127_949588_4 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000001404 154.0
HKD2_k127_9498473_0 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 544.0
HKD2_k127_9498473_1 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 505.0
HKD2_k127_9498473_2 Protein of unknown function (DUF2797) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 405.0
HKD2_k127_9498473_3 Belongs to the UPF0336 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003745 274.0
HKD2_k127_9498473_4 PFAM alpha amylase, catalytic K01187 - 3.2.1.20 0.00000000000000000000000000000000000000897 145.0
HKD2_k127_9498473_5 Protein of unknown function (DUF3188) - - - 0.00000000000000000000000000001465 118.0
HKD2_k127_9521141_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 6.944e-209 651.0
HKD2_k127_9521141_1 Fusaric acid resistance protein-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 500.0
HKD2_k127_9565187_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10548 - 3.6.3.17 8.578e-310 952.0
HKD2_k127_9565187_1 Belongs to the binding-protein-dependent transport system permease family K10547 - - 0.000000000000000000000000000000001043 131.0
HKD2_k127_9565187_2 ROK family - - - 0.00000000000000000000000000000009053 124.0
HKD2_k127_9618205_0 Dehydrogenase E1 component K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 5.418e-278 861.0
HKD2_k127_9618205_1 IMP dehydrogenase / GMP reductase domain K00088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.1.1.205 9.941e-271 839.0
HKD2_k127_9620185_0 TPM domain - - - 1.827e-320 995.0
HKD2_k127_9620185_1 Phage shock protein A, PspA K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 454.0
HKD2_k127_9620185_2 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000004023 194.0
HKD2_k127_9620185_3 TPM domain - - - 0.0007066 46.0
HKD2_k127_9640220_0 manually curated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 422.0
HKD2_k127_9640220_1 Winged helix-turn helix - - - 0.00000000000000000001583 94.0
HKD2_k127_9640220_2 Type IV secretion-system coupling protein DNA-binding domain - - - 0.00000000000004112 78.0
HKD2_k127_9650059_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 550.0
HKD2_k127_9650059_1 Glycosyl transferase - - - 0.0000002238 53.0
HKD2_k127_9659463_0 Belongs to the aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 9.391e-298 915.0
HKD2_k127_9659463_1 Purine catabolism regulatory protein-like family K09684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008322 258.0
HKD2_k127_9659463_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000008797 113.0
HKD2_k127_96728_0 Phosphotransferase system, EIIC K02798,K02799,K02800 - 2.7.1.197 0.0 1099.0
HKD2_k127_96728_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0 1053.0
HKD2_k127_96728_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 5.981e-302 932.0
HKD2_k127_96728_3 PucR C-terminal helix-turn-helix domain - - - 2.389e-230 719.0
HKD2_k127_96728_4 Belongs to the AlaDH PNT family K00259 GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030312,GO:0036293,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 2.385e-223 701.0
HKD2_k127_96728_5 Mannitol-1-phosphate 5-dehydrogenase K00009 - 1.1.1.17 8.419e-207 647.0
HKD2_k127_96728_6 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 556.0
HKD2_k127_96728_7 Belongs to the ABC transporter superfamily K02031,K02032 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 526.0
HKD2_k127_96728_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 406.0
HKD2_k127_96728_9 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000002134 218.0
HKD2_k127_9674270_0 PFAM MULE transposase, conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 391.0
HKD2_k127_9674270_1 manually curated - - - 0.000134 44.0
HKD2_k127_9682199_0 ABC transporter K05847 - - 2.806e-194 610.0
HKD2_k127_9682199_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 548.0
HKD2_k127_9682199_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 552.0
HKD2_k127_9682199_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 270.0
HKD2_k127_9682199_4 Binding-protein-dependent transport system inner membrane component K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008446 253.0
HKD2_k127_9682199_5 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000004609 66.0
HKD2_k127_9685220_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 551.0
HKD2_k127_9685220_1 Ppx/GppA phosphatase family K01524 GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008797 286.0
HKD2_k127_9685220_2 SseB protein N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001058 255.0
HKD2_k127_9687264_0 collagen metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 403.0
HKD2_k127_9703814_0 Na H antiporter K03316 - - 3.576e-234 726.0
HKD2_k127_9703814_1 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 385.0
HKD2_k127_9721938_0 Glutathione S-transferase, C-terminal domain K07393 - 1.8.5.7 6.726e-219 679.0
HKD2_k127_9721938_1 KR domain K00059 - 1.1.1.100 1.015e-216 677.0
HKD2_k127_9721938_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 532.0
HKD2_k127_9721938_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 544.0
HKD2_k127_9721938_4 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008489 481.0
HKD2_k127_9739649_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 406.0
HKD2_k127_9739649_1 Sterol carrier protein - - - 0.000000000000000000000000000000000000000000000000000000002734 203.0
HKD2_k127_9739649_2 CHAD - - - 0.00009243 46.0
HKD2_k127_9743100_0 efflux transmembrane transporter activity - - - 0.0 1549.0
HKD2_k127_9743100_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 5.113e-235 728.0
HKD2_k127_9743100_2 lipoprotein transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 482.0
HKD2_k127_9743100_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 437.0
HKD2_k127_978399_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 366.0
HKD2_k127_978399_1 Domain of unknown function (DUF296) - - - 0.0000000000000000000000000000000296 128.0
HKD2_k127_978399_2 Transposase and inactivated derivatives IS30 family K07482 - - 0.000000006864 63.0
HKD2_k127_978399_3 Sulfotransferase family - - - 0.000001297 52.0
HKD2_k127_978399_4 required for the transposition of insertion element IS2404 - - - 0.000005682 48.0
HKD2_k127_978399_5 sequence-specific DNA binding - - - 0.000308 49.0
HKD2_k127_9806677_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 416.0
HKD2_k127_9806677_1 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 299.0
HKD2_k127_9806677_2 PFAM Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007967 259.0
HKD2_k127_9806677_3 PFAM Transposase IS66 family K07484 - - 0.00000000000000000000000000000000001621 136.0
HKD2_k127_9824452_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 5e-324 1001.0
HKD2_k127_9851202_0 FAD binding domain - - - 1.998e-201 633.0
HKD2_k127_9851202_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 514.0
HKD2_k127_9851202_2 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 352.0
HKD2_k127_9851202_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 314.0
HKD2_k127_9851202_4 membrane protein (DUF2078) K08982 - - 0.000000000000000000000000000000000000001189 148.0
HKD2_k127_9851202_6 e3 binding domain K00627,K00658 - 2.3.1.12,2.3.1.61 0.00000000000000000000000000000000003962 134.0
HKD2_k127_9851202_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000000000000000000000000000001373 124.0
HKD2_k127_9858845_0 Protein of unknown function (DUF3618) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003615 274.0
HKD2_k127_9858845_1 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009154 267.0
HKD2_k127_9858845_2 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000000000000000000000000000000000000000000000000000007168 221.0
HKD2_k127_9858845_3 ribonuclease BN K07058 - - 0.000000000000000000000000000000000001316 139.0
HKD2_k127_9858845_4 O-methyltransferase activity - - - 0.000000000000000000000000000000000001927 139.0
HKD2_k127_9870289_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 489.0
HKD2_k127_9870289_1 NUDIX domain K18568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 417.0
HKD2_k127_9870289_2 - - - - 0.00000000000000000000000000000000000007395 142.0
HKD2_k127_9870289_3 double-strand break repair K09946 - - 0.00000000000005213 74.0
HKD2_k127_9888038_0 PFAM Transposase Tn5 dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000009245 225.0
HKD2_k127_9888038_1 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000009015 142.0
HKD2_k127_9910686_0 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 442.0
HKD2_k127_9910686_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003778 267.0
HKD2_k127_9916181_0 Glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 1.531e-311 959.0
HKD2_k127_9916181_1 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 517.0
HKD2_k127_9916181_2 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.0000000000000000000000000000000000000000001034 159.0
HKD2_k127_9989866_0 COG5659 FOG Transposase - - - 1.119e-245 764.0
HKD2_k127_9989866_1 transposition - - - 0.0000000000000000000000000000003284 131.0
HKD2_k127_9989866_2 ISXO2-like transposase domain - - - 0.00000007591 57.0