HKD2_k127_10118740_0
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K03723
-
-
0.0
1115.0
View
HKD2_k127_10118740_1
Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
K01689
-
4.2.1.11
1.791e-204
643.0
View
HKD2_k127_10118740_10
DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K10773
-
4.2.99.18
0.0000000000000000000000000000000000000000000000000000000000000000000007497
253.0
View
HKD2_k127_10118740_11
Protein of unknown function (DUF554)
K07150
-
-
0.00000000000000000000000000000000000000000000000000000000004732
213.0
View
HKD2_k127_10118740_12
Protein of unknown function (DUF1003)
-
-
-
0.00000000000000000000000000000000000000000000000002218
183.0
View
HKD2_k127_10118740_13
peptidyl-prolyl isomerase
K07533
-
5.2.1.8
0.000000000000000000000000000000001864
142.0
View
HKD2_k127_10118740_14
deacetylase
K22278
-
3.5.1.104
0.000000000000000000000000000008172
138.0
View
HKD2_k127_10118740_15
Redoxin
K03564
-
1.11.1.15
0.000000000000000000003962
96.0
View
HKD2_k127_10118740_16
PFAM blue (type 1) copper domain protein
-
-
-
0.0000000000000004537
87.0
View
HKD2_k127_10118740_17
Alkyl hydroperoxide reductase
K03564
-
1.11.1.15
0.00000007512
55.0
View
HKD2_k127_10118740_18
Produces ATP from ADP in the presence of a proton gradient across the membrane
K02114
GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600
-
0.0001167
48.0
View
HKD2_k127_10118740_19
belongs to the nudix hydrolase family
-
-
-
0.0001997
51.0
View
HKD2_k127_10118740_2
Protein of unknown function, DUF255
K06888
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211
401.0
View
HKD2_k127_10118740_3
Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K02112
-
3.6.3.14
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695
370.0
View
HKD2_k127_10118740_4
Belongs to the DEAD box helicase family
K11927
-
3.6.4.13
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037
359.0
View
HKD2_k127_10118740_5
Belongs to the pyruvate kinase family
K00873
-
2.7.1.40
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407
353.0
View
HKD2_k127_10118740_6
Threonine aldolase
K01620
-
4.1.2.48
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195
361.0
View
HKD2_k127_10118740_7
TIGRFAM MazG family protein
K02428,K02499
-
3.6.1.66
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004384
305.0
View
HKD2_k127_10118740_8
PFAM 4Fe-4S binding domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000005557
291.0
View
HKD2_k127_10118740_9
Domain of unknown function (DUF362)
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000008904
254.0
View
HKD2_k127_140563_0
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
K00962
GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575
2.7.7.8
2.923e-236
749.0
View
HKD2_k127_140563_1
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K02956
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904
-
0.0000000000000000000000000000000229
127.0
View
HKD2_k127_140563_2
Isoprenylcysteine carboxyl methyltransferase (ICMT) family
-
-
-
0.000000000000009833
81.0
View
HKD2_k127_1408760_0
single-stranded-DNA-specific exonuclease RecJ
K07462
-
-
0.0
1062.0
View
HKD2_k127_1408760_1
In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K00951
-
2.7.6.5
7.066e-277
874.0
View
HKD2_k127_1408760_10
PFAM AMP-dependent synthetase and ligase
K00666
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001521
282.0
View
HKD2_k127_1408760_11
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K03072,K12257
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000001505
282.0
View
HKD2_k127_1408760_12
Metal dependent phosphohydrolases with conserved 'HD' motif.
K09163
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000004526
249.0
View
HKD2_k127_1408760_13
LemA family
K03744
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000002866
243.0
View
HKD2_k127_1408760_14
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
K08681
GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600
4.3.3.6
0.00000000000000000000000000000000000000000000000000000000000000000001746
237.0
View
HKD2_k127_1408760_15
Rhomboid family
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000805
236.0
View
HKD2_k127_1408760_16
Protein of unknown function (DUF3048) C-terminal domain
-
-
-
0.00000000000000000000000000000000000000000000000000000002308
212.0
View
HKD2_k127_1408760_17
PFAM Metallo-beta-lactamase superfamily
-
-
-
0.000000000000000000000000000000000000000000000002712
180.0
View
HKD2_k127_1408760_18
Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
K01159
-
3.1.22.4
0.00000000000000000000000000000000000000000000003859
176.0
View
HKD2_k127_1408760_19
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K09765
-
1.17.99.6
0.000000000000000000000000000000000000000000002568
170.0
View
HKD2_k127_1408760_2
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
K06215
-
4.3.3.6
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135
496.0
View
HKD2_k127_1408760_20
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
K03550
-
3.6.4.12
0.00000000000000000000000000000000000000000001307
169.0
View
HKD2_k127_1408760_21
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
-
-
-
0.0000000000000000000000000000000000000193
155.0
View
HKD2_k127_1408760_22
Uncharacterized protein family UPF0016
-
-
-
0.00000000000000000000000000000000001077
145.0
View
HKD2_k127_1408760_23
'Cold-shock' DNA-binding domain
K03704
-
-
0.0000000000000000000000000000000001503
132.0
View
HKD2_k127_1408760_24
SMART phosphoesterase PHP domain protein
-
-
-
0.0000000000000000000000000000001775
134.0
View
HKD2_k127_1408760_25
TIGRFAM RNA polymerase sigma factor, sigma-70 family
K03088
-
-
0.000000000000000000000000001026
120.0
View
HKD2_k127_1408760_26
superoxide reductase activity
K05919
-
1.15.1.2
0.00000000000000007971
87.0
View
HKD2_k127_1408760_27
Preprotein translocase
K03210
-
-
0.000000000000002244
79.0
View
HKD2_k127_1408760_28
peptidase M48, Ste24p
-
-
-
0.0009024
51.0
View
HKD2_k127_1408760_3
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
K03551
-
3.6.4.12
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679
496.0
View
HKD2_k127_1408760_4
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
K00773
-
2.4.2.29
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139
416.0
View
HKD2_k127_1408760_5
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K03072,K12257
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037
392.0
View
HKD2_k127_1408760_6
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K07568
-
2.4.99.17
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083
383.0
View
HKD2_k127_1408760_7
Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K01491
-
1.5.1.5,3.5.4.9
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106
341.0
View
HKD2_k127_1408760_8
transcriptional regulatory protein
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659
326.0
View
HKD2_k127_1408760_9
Prolipoprotein diacylglyceryl transferase
K13292
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001772
292.0
View
HKD2_k127_1433654_0
cyclic 2,3-diphosphoglycerate synthetase activity
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192
499.0
View
HKD2_k127_1433654_1
Amino acid kinase family
K00926
-
2.7.2.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000029
295.0
View
HKD2_k127_1433654_10
calcium- and calmodulin-responsive adenylate cyclase activity
K08372
-
-
0.000000000000000000000000000005484
134.0
View
HKD2_k127_1433654_11
-
-
-
-
0.0000000000000000000001035
103.0
View
HKD2_k127_1433654_12
Tetracyclin repressor, C-terminal all-alpha domain
-
-
-
0.000000000000000000006975
100.0
View
HKD2_k127_1433654_13
-
-
-
-
0.00000000000000000006039
99.0
View
HKD2_k127_1433654_14
Uncharacterized ACR, COG1430
K09005
-
-
0.00000000002303
74.0
View
HKD2_k127_1433654_2
DegV family
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000005384
258.0
View
HKD2_k127_1433654_3
Mitochondrial biogenesis AIM24
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000001227
228.0
View
HKD2_k127_1433654_4
TIGRFAM degV family protein
-
-
-
0.00000000000000000000000000000000000000000000000000000000004792
218.0
View
HKD2_k127_1433654_5
N-acetylmuramoyl-L-alanine amidase
K01448
-
3.5.1.28
0.0000000000000000000000000000000000000000000000000000002992
210.0
View
HKD2_k127_1433654_6
Flavodoxin domain
K00230
-
1.3.5.3
0.0000000000000000000000000000000000000000002759
167.0
View
HKD2_k127_1433654_7
calcium- and calmodulin-responsive adenylate cyclase activity
K08372
-
-
0.000000000000000000000000000000000000001961
158.0
View
HKD2_k127_1433654_8
Protein of unknown function (DUF2089)
-
-
-
0.0000000000000000000000000000000000005045
143.0
View
HKD2_k127_1433654_9
GyrI-like small molecule binding domain
-
-
-
0.0000000000000000000000000000000001485
138.0
View
HKD2_k127_1437130_0
ABC transporter
K06158
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194
499.0
View
HKD2_k127_1437130_1
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K00333
-
1.6.5.3
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145
403.0
View
HKD2_k127_1437130_2
electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration
K05582
-
1.6.5.3
0.00000000000000000000000000000000000000000000000001917
189.0
View
HKD2_k127_1437130_3
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K00332
GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564
1.6.5.3
0.0000000000000000000000000000001698
128.0
View
HKD2_k127_1437130_4
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K00330
-
1.6.5.3
0.00000000000000005566
87.0
View
HKD2_k127_1437130_5
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K00337
-
1.6.5.3
0.000000000000001182
82.0
View
HKD2_k127_1769284_0
DNA polymerase III alpha subunit
K02337
-
2.7.7.7
4.924e-308
970.0
View
HKD2_k127_1769284_1
Belongs to the alpha-IPM synthase homocitrate synthase family
K01649
-
2.3.3.13
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217
601.0
View
HKD2_k127_1769284_2
PFAM fumarylacetoacetate (FAA) hydrolase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000222
287.0
View
HKD2_k127_1769284_3
Diguanylate cyclase phosphodiesterase with PAS PAC and GAF sensor(S)
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000003278
277.0
View
HKD2_k127_1769284_4
Transmembrane secretion effector
-
-
-
0.000000000000000000000000000000000000000000000008712
190.0
View
HKD2_k127_1769284_5
DNA polymerase III alpha subunit
K02337
-
2.7.7.7
0.00000000000000000000000000000000000000000001303
170.0
View
HKD2_k127_1769284_6
TrpR family protein YerC YecD
-
-
-
0.000000000000000000000000005795
113.0
View
HKD2_k127_1769284_7
His Kinase A (phosphoacceptor) domain
-
-
-
0.00000000002916
77.0
View
HKD2_k127_1849564_0
Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K01939
-
6.3.4.4
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656
602.0
View
HKD2_k127_1849564_1
Elongator protein 3, MiaB family, Radical SAM
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903
572.0
View
HKD2_k127_1849564_10
'Cold-shock' DNA-binding domain
K03704
-
-
0.00000000000000000000000000001116
119.0
View
HKD2_k127_1849564_11
regulation of RNA biosynthetic process
-
-
-
0.000000000000000000000000002698
118.0
View
HKD2_k127_1849564_12
Acetyltransferase (GNAT) domain
-
-
-
0.000000000000000006061
88.0
View
HKD2_k127_1849564_13
Antibiotic biosynthesis monooxygenase
-
-
-
0.0000000000000296
78.0
View
HKD2_k127_1849564_14
RmlD substrate binding domain
-
-
-
0.0000000000001041
78.0
View
HKD2_k127_1849564_2
Belongs to the GARS family
K01945
-
6.3.4.13
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511
484.0
View
HKD2_k127_1849564_3
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
K06949
-
3.1.3.100
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492
376.0
View
HKD2_k127_1849564_4
carboxylic ester hydrolase activity
K15357
-
3.5.1.106
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845
329.0
View
HKD2_k127_1849564_5
-
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000001878
276.0
View
HKD2_k127_1849564_6
Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K01588
-
5.4.99.18
0.000000000000000000000000000000000000000000000000000000000000000000001656
238.0
View
HKD2_k127_1849564_7
protein conserved in bacteria
-
-
-
0.000000000000000000000000000000000000000000000000000005375
191.0
View
HKD2_k127_1849564_8
PFAM Isoprenylcysteine carboxyl methyltransferase
-
-
-
0.00000000000000000000000000000000000000000000000000004833
196.0
View
HKD2_k127_1849564_9
Flavodoxin domain
K00230
-
1.3.5.3
0.000000000000000000000000000000000005839
142.0
View
HKD2_k127_192098_0
Amino acid permease
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036
561.0
View
HKD2_k127_192098_1
Uncharacterised protein family (UPF0182)
K09118
GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724
538.0
View
HKD2_k127_192098_10
PFAM metal-dependent phosphohydrolase HD sub domain
-
-
-
0.000000000000000000000000000000000000000000000000000002459
220.0
View
HKD2_k127_192098_11
-
-
-
-
0.00000000000000000000000000000000000000000000000000004774
202.0
View
HKD2_k127_192098_12
PFAM ABC-2 type transporter
K01992
-
-
0.00000000000000000000000000000000000000000002313
176.0
View
HKD2_k127_192098_13
Major facilitator Superfamily
K03291
-
-
0.000000000000000000000000000000000000000005754
172.0
View
HKD2_k127_192098_14
COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2
K03775
-
5.2.1.8
0.0000000000000000000000000000000000000004811
154.0
View
HKD2_k127_192098_15
PFAM ABC-2 type transporter
K01992
-
-
0.00000000000000000000000000000000000008955
165.0
View
HKD2_k127_192098_16
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
-
-
-
0.0000000000000000000000000000000000001441
160.0
View
HKD2_k127_192098_17
amidohydrolase
K07045
-
-
0.000000000000000000000000000000000005195
149.0
View
HKD2_k127_192098_18
Metal dependent phosphohydrolases with conserved 'HD' motif.
-
-
-
0.0000000000000000000000000000000001369
148.0
View
HKD2_k127_192098_19
Maf-like protein
K06287
GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944
-
0.000000000000000000000000000003995
128.0
View
HKD2_k127_192098_2
Transporter associated domain
K03699
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025
402.0
View
HKD2_k127_192098_20
PFAM Methyltransferase type 11
-
-
-
0.0000000000000000000000000005725
131.0
View
HKD2_k127_192098_21
TIGRFAM Ammonium transporter
K03320
-
-
0.00000000000000000000000006828
114.0
View
HKD2_k127_192098_22
acylphosphatase activity
K01512
GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818
3.6.1.7
0.000000000000000000003552
96.0
View
HKD2_k127_192098_23
lyase activity
-
-
-
0.00000000000000001432
98.0
View
HKD2_k127_192098_24
acetyltransferase
-
GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747
-
0.00000000006262
75.0
View
HKD2_k127_192098_25
Phage-shock protein
K03973
-
-
0.0000000006881
68.0
View
HKD2_k127_192098_26
-
-
-
-
0.000002312
59.0
View
HKD2_k127_192098_27
Transcriptional regulator
-
-
-
0.0002306
49.0
View
HKD2_k127_192098_3
pfam abc
K01990,K09695
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659
353.0
View
HKD2_k127_192098_4
EamA-like transporter family
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009371
301.0
View
HKD2_k127_192098_5
DNA alkylation repair enzyme
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000002497
244.0
View
HKD2_k127_192098_6
Uncharacterised protein family (UPF0182)
K09118
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000008442
244.0
View
HKD2_k127_192098_7
channel protein, hemolysin III family
K11068
-
-
0.00000000000000000000000000000000000000000000000000000000000000007134
231.0
View
HKD2_k127_192098_8
COG2041 Sulfite oxidase and related enzymes
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000221
239.0
View
HKD2_k127_192098_9
PFAM Glutamine amidotransferase class-I
K01951
-
6.3.5.2
0.00000000000000000000000000000000000000000000000000000002504
205.0
View
HKD2_k127_1931731_0
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K15633
-
5.4.2.12
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787
574.0
View
HKD2_k127_1931731_1
ABC transporter, ATP-binding protein
K10823
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724
456.0
View
HKD2_k127_1931731_10
UvrD REP helicase
K03657,K07465
-
3.6.4.12
0.000000000000000000000000000000000000000000000000000000000000000000000000000000006767
298.0
View
HKD2_k127_1931731_11
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
K01803
-
5.3.1.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000009644
277.0
View
HKD2_k127_1931731_12
PFAM ATP-binding region, ATPase domain protein
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000007583
287.0
View
HKD2_k127_1931731_13
Predicted membrane protein (DUF2207)
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000001894
281.0
View
HKD2_k127_1931731_14
PFAM Glycosyl transferase, group 1
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000001059
264.0
View
HKD2_k127_1931731_15
diacylglycerol kinase catalytic
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000008351
244.0
View
HKD2_k127_1931731_16
phosphatase activity
K07025
-
-
0.00000000000000000000000000000000000000000000000001737
187.0
View
HKD2_k127_1931731_17
Protein of unknown function (DUF4080)
K04034
-
1.21.98.3
0.0000000000000000000000000000000000000000000000001846
200.0
View
HKD2_k127_1931731_18
Cytochrome C biogenesis protein transmembrane region
K06196
-
-
0.0000000000000000000000000000000000000000000000007397
183.0
View
HKD2_k127_1931731_19
Belongs to the phosphoglycerate kinase family
K00927
-
2.7.2.3
0.000000000000000000000000000000000000000000000009317
174.0
View
HKD2_k127_1931731_2
PFAM extracellular solute-binding protein, family 5
K02035
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009875
460.0
View
HKD2_k127_1931731_20
RecQ zinc-binding
K03654
-
3.6.4.12
0.00000000000000000000000000000000000000000000006028
176.0
View
HKD2_k127_1931731_21
Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
K03186
-
2.5.1.129
0.00000000000000000000000000000000000000000000008073
175.0
View
HKD2_k127_1931731_22
SMART phosphoesterase PHP domain protein
-
-
-
0.00000000000000000000000000000000000000008119
162.0
View
HKD2_k127_1931731_23
SMART protein phosphatase 2C domain protein
-
-
-
0.0000000000000000000000000000000000000004344
173.0
View
HKD2_k127_1931731_24
Heavy metal transport detoxification protein
-
-
-
0.00000000000000000000000000000000000074
155.0
View
HKD2_k127_1931731_25
'Cold-shock' DNA-binding domain
K03704
-
-
0.000000000000000000000000000000006967
132.0
View
HKD2_k127_1931731_26
Belongs to the anti-sigma-factor antagonist family
-
-
-
0.0000000000000000000000000000001672
134.0
View
HKD2_k127_1931731_27
EamA-like transporter family
-
-
-
0.0000000000000000000000000000005781
136.0
View
HKD2_k127_1931731_28
PFAM Nitroreductase
-
-
-
0.00000000000000000000000004825
115.0
View
HKD2_k127_1931731_29
Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
-
-
-
0.0000000000000000000007511
105.0
View
HKD2_k127_1931731_3
two component, sigma54 specific, transcriptional regulator, Fis family
K02481
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397
437.0
View
HKD2_k127_1931731_30
Domain of unknown function DUF302
-
-
-
0.00000000000000000268
90.0
View
HKD2_k127_1931731_31
mannose-ethanolamine phosphotransferase activity
K05288
-
-
0.0000000000000001359
94.0
View
HKD2_k127_1931731_32
Metal-sensitive transcriptional repressor
K21600
-
-
0.00000000000001432
80.0
View
HKD2_k127_1931731_33
Preprotein translocase SecG subunit
K03075
-
-
0.00000000000008366
75.0
View
HKD2_k127_1931731_34
UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
K03429
GO:0003674,GO:0003824,GO:0008194,GO:0016740,GO:0016757,GO:0016758,GO:0035251,GO:0046527,GO:0047228
2.4.1.315
0.00000000005841
75.0
View
HKD2_k127_1931731_35
-
-
-
-
0.0000000002473
66.0
View
HKD2_k127_1931731_36
Heavy-metal-associated domain
K01533,K07213,K07496,K17686
-
3.6.3.4,3.6.3.54
0.00000009437
57.0
View
HKD2_k127_1931731_37
Elongator protein 3, MiaB family, Radical SAM
K06139
-
-
0.000005695
58.0
View
HKD2_k127_1931731_4
aminotransferase class I and II
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204
431.0
View
HKD2_k127_1931731_5
Belongs to the ABC transporter superfamily
K02031
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693
389.0
View
HKD2_k127_1931731_6
Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
K03684
-
3.1.13.5
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084
343.0
View
HKD2_k127_1931731_7
PFAM binding-protein-dependent transport systems inner membrane component
K02034
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262
310.0
View
HKD2_k127_1931731_8
Sigma-54 factor, Activator interacting domain (AID)
K03092
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721
305.0
View
HKD2_k127_1931731_9
PFAM binding-protein-dependent transport systems inner membrane component
K02033
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000492
291.0
View
HKD2_k127_2148941_0
heavy metal translocating P-type ATPase
K01533,K17686
-
3.6.3.4,3.6.3.54
8.614e-277
866.0
View
HKD2_k127_2148941_1
Belongs to the glutamate synthase family
K00265
-
1.4.1.13,1.4.1.14
3.306e-219
711.0
View
HKD2_k127_2148941_10
PFAM glutamate synthase alpha subunit
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001912
286.0
View
HKD2_k127_2148941_11
Signal transduction histidine kinase
K00936
GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564
2.7.13.3
0.00000000000000000000000000000000000000000000000000000000000000000000000002411
270.0
View
HKD2_k127_2148941_12
Major Facilitator Superfamily
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000005086
265.0
View
HKD2_k127_2148941_13
Major facilitator Superfamily
-
-
-
0.000000000000000000000000000000000000000000000000000000000000002644
234.0
View
HKD2_k127_2148941_14
Response regulator receiver
K22010
GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944
-
0.00000000000000000000000000000000000000000000000000000000000001539
231.0
View
HKD2_k127_2148941_15
TIGRFAM methionine biosynthesis protein MetW
-
-
-
0.00000000000000000000000000000000000000000000000000000000000009614
222.0
View
HKD2_k127_2148941_16
PFAM Class II aldolase
K01628
-
4.1.2.17
0.000000000000000000000000000000000000000002372
164.0
View
HKD2_k127_2148941_17
HD domain
-
-
-
0.000000000000000000000000000000000002338
154.0
View
HKD2_k127_2148941_18
D-glucuronyl C5-epimerase C-terminus
-
-
-
0.000000000000000000005431
107.0
View
HKD2_k127_2148941_19
Cytochrome C oxidase, cbb3-type, subunit III
K02275
-
1.9.3.1
0.00000000000000000007659
97.0
View
HKD2_k127_2148941_2
PFAM Cys Met metabolism
K01740
-
2.5.1.49
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083
553.0
View
HKD2_k127_2148941_20
transcriptional regulator, Rrf2 family
-
-
-
0.000000000000005276
80.0
View
HKD2_k127_2148941_21
PBS lyase HEAT-like repeat
-
-
-
0.000000000000008989
85.0
View
HKD2_k127_2148941_22
membrane
-
-
-
0.0000000000001597
79.0
View
HKD2_k127_2148941_23
-
-
-
-
0.000002139
60.0
View
HKD2_k127_2148941_24
Short C-terminal domain
K08982
-
-
0.0002171
48.0
View
HKD2_k127_2148941_3
Cys/Met metabolism PLP-dependent enzyme
K01739,K01758
-
2.5.1.48,4.4.1.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834
458.0
View
HKD2_k127_2148941_4
Glutamate synthase (NADPH) GltB1 subunit
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317
459.0
View
HKD2_k127_2148941_5
Pyridoxal-phosphate dependent enzyme
K01697
-
4.2.1.22
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429
427.0
View
HKD2_k127_2148941_6
Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K00641
-
2.3.1.31
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256
422.0
View
HKD2_k127_2148941_7
Belongs to the cysteine synthase cystathionine beta- synthase family
K01738
GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009333,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234
2.5.1.47
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837
338.0
View
HKD2_k127_2148941_8
Cysteine-rich domain
K03389
-
1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036
333.0
View
HKD2_k127_2148941_9
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003912
291.0
View
HKD2_k127_2197221_0
ATPase, P-type (transporting), HAD superfamily, subfamily IC
K01537
-
3.6.3.8
0.0
1023.0
View
HKD2_k127_2197221_1
Phenylalanyl-tRNA synthetase, beta subunit
K01890
-
6.1.1.20
5.933e-246
784.0
View
HKD2_k127_2197221_10
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K00620
-
2.3.1.1,2.3.1.35
0.000000000000000000000000000003593
129.0
View
HKD2_k127_2197221_11
Belongs to the bacterial ribosomal protein bL35 family
K02916
-
-
0.00000000000000004049
83.0
View
HKD2_k127_2197221_12
Peptidase S24-like
K13280
-
3.4.21.89
0.000006525
57.0
View
HKD2_k127_2197221_2
Sugar (and other) transporter
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535
523.0
View
HKD2_k127_2197221_3
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K01889
-
6.1.1.20
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014
482.0
View
HKD2_k127_2197221_4
PFAM Signal transduction histidine kinase, osmosensitive K channel sensor, N-terminal
K07646
-
2.7.13.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564
383.0
View
HKD2_k127_2197221_5
Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K00145
-
1.2.1.38
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026
321.0
View
HKD2_k127_2197221_6
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K02520
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000005336
260.0
View
HKD2_k127_2197221_7
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
K01547
GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351
3.6.3.12
0.00000000000000000000000000000000000000000000000000000000001579
208.0
View
HKD2_k127_2197221_8
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K02887
-
-
0.000000000000000000000000000000000000000000000000001004
184.0
View
HKD2_k127_2197221_9
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
K01548
-
3.6.3.12
0.0000000000000000000000000000000000000000000000009422
187.0
View
HKD2_k127_221567_0
Iron-sulfur cluster-binding domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807
576.0
View
HKD2_k127_221567_1
Belongs to the ALAD family
K01698
-
4.2.1.24
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382
482.0
View
HKD2_k127_221567_2
Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
K02492
-
1.2.1.70
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095
433.0
View
HKD2_k127_221567_3
signal transduction protein containing a membrane domain an EAL and a GGDEF domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374
398.0
View
HKD2_k127_221567_4
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
K01749
GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
2.5.1.61
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158
326.0
View
HKD2_k127_221567_5
Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase
K02302,K02303,K13542
-
1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4
0.00000000000000000000000000000000000000000000000000000000000005587
222.0
View
HKD2_k127_221567_6
Belongs to the short-chain dehydrogenases reductases (SDR) family
-
-
-
0.0000000000000000000000000000000000000000000000000000008565
207.0
View
HKD2_k127_221567_7
Sirohaem synthase dimerisation region
K02304
-
1.3.1.76,4.99.1.4
0.000000000000000000000000004673
119.0
View
HKD2_k127_221567_8
Cytochrome c assembly protein
-
-
-
0.0000000004127
70.0
View
HKD2_k127_221567_9
Radical SAM domain protein
K04070
-
1.97.1.4
0.00004849
48.0
View
HKD2_k127_2270203_0
Clp domain protein
K03696
GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944
-
0.0
1138.0
View
HKD2_k127_2270203_1
Belongs to the class-II aminoacyl-tRNA synthetase family
K04567
-
6.1.1.6
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252
600.0
View
HKD2_k127_2270203_10
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
K01770
-
4.6.1.12
0.00000000000000000000000000000000000000000000000000000000001663
211.0
View
HKD2_k127_2270203_11
PFAM HD domain
K03698
-
-
0.0000000000000000000000000000000000000000000000000000002551
206.0
View
HKD2_k127_2270203_12
Modulates transcription in response to changes in cellular NADH NAD( ) redox state
K01926
-
-
0.0000000000000000000000000000000000000000000000000000009216
200.0
View
HKD2_k127_2270203_13
Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
K00991
-
2.7.7.60
0.0000000000000000000000000000000000000000000000000007615
200.0
View
HKD2_k127_2270203_14
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
K03624
-
-
0.000000000000000000000000000000000000000000458
168.0
View
HKD2_k127_2270203_15
Cyclic nucleotide-monophosphate binding domain
-
-
-
0.000000000000000000000001094
110.0
View
HKD2_k127_2270203_16
Predicted membrane protein (DUF2085)
-
-
-
0.0000000000000001344
88.0
View
HKD2_k127_2270203_17
NACHT domain
-
-
-
0.0000000000000004961
92.0
View
HKD2_k127_2270203_18
protein folding in endoplasmic reticulum
K19134
-
-
0.0000000002355
71.0
View
HKD2_k127_2270203_19
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
K03116
-
-
0.00000001718
59.0
View
HKD2_k127_2270203_2
Belongs to the class-I aminoacyl-tRNA synthetase family
K01883
-
6.1.1.16
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419
497.0
View
HKD2_k127_2270203_20
Evidence 5 No homology to any previously reported sequences
-
-
-
0.00004127
47.0
View
HKD2_k127_2270203_3
DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K04485
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279
423.0
View
HKD2_k127_2270203_4
Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage
K00772
-
2.4.2.28
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007574
368.0
View
HKD2_k127_2270203_5
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
K07067
-
2.7.7.85
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796
326.0
View
HKD2_k127_2270203_6
Large family of predicted nucleotide-binding domains
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000287
263.0
View
HKD2_k127_2270203_7
serine O-acetyltransferase
K00640
-
2.3.1.30
0.00000000000000000000000000000000000000000000000000000000000000000000000009234
256.0
View
HKD2_k127_2270203_8
Belongs to the sigma-70 factor family
K03091
-
-
0.00000000000000000000000000000000000000000000000000000000000001014
223.0
View
HKD2_k127_2270203_9
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K03218
-
2.1.1.185
0.00000000000000000000000000000000000000000000000000000000001503
233.0
View
HKD2_k127_2280367_0
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K01649
-
2.3.3.13
4.273e-216
682.0
View
HKD2_k127_2280367_1
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K01703
-
4.2.1.33,4.2.1.35
4.114e-211
662.0
View
HKD2_k127_2280367_10
Histidine kinase
K11527
-
2.7.13.3
0.0000000000000000000000000000001396
131.0
View
HKD2_k127_2280367_11
Tetracyclin repressor, C-terminal all-alpha domain
-
-
-
0.00000000000000000000000001941
117.0
View
HKD2_k127_2280367_12
Flavodoxin domain
K00230
-
1.3.5.3
0.000000000000000000000113
104.0
View
HKD2_k127_2280367_2
D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
K00058
-
1.1.1.399,1.1.1.95
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009295
554.0
View
HKD2_k127_2280367_3
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K00053
-
1.1.1.86
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723
476.0
View
HKD2_k127_2280367_4
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
K00052
-
1.1.1.85
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214
423.0
View
HKD2_k127_2280367_5
PFAM aminotransferase class V
-
GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484
402.0
View
HKD2_k127_2280367_6
Branched-chain amino acid aminotransferase
K00826
-
2.6.1.42
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023
391.0
View
HKD2_k127_2280367_7
Nadph-dependent fmn reductase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399
330.0
View
HKD2_k127_2280367_8
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K01704
-
4.2.1.33,4.2.1.35
0.0000000000000000000000000000000000000000000000000000000000000000000000000000004899
266.0
View
HKD2_k127_2280367_9
ACT domain
K01653
-
2.2.1.6
0.0000000000000000000000000000000000000000000000000000002565
196.0
View
HKD2_k127_2526721_0
DNA topoisomerase
K03168
-
5.99.1.2
2.989e-259
822.0
View
HKD2_k127_2526721_1
SMART Elongator protein 3 MiaB NifB
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484
482.0
View
HKD2_k127_2526721_10
Belongs to the anti-sigma-factor antagonist family
K04749
GO:0003674,GO:0005488,GO:0005515,GO:0042802
-
0.00000000000000000000000000000368
123.0
View
HKD2_k127_2526721_11
PFAM Positive regulator of sigma(E) RseC MucC
K03803
-
-
0.00000003086
66.0
View
HKD2_k127_2526721_12
Twin arginine-targeting protein translocase, TatA E family
K03117,K03646
-
-
0.00000009107
60.0
View
HKD2_k127_2526721_13
antisigma factor binding
K04749,K17763,K20978
-
-
0.000001109
56.0
View
HKD2_k127_2526721_14
Fumarate hydratase (Fumerase)
K01677
-
4.2.1.2
0.000006552
54.0
View
HKD2_k127_2526721_15
Glycosyltransferase like family
-
-
-
0.0003825
52.0
View
HKD2_k127_2526721_2
Amidohydrolase family
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099
429.0
View
HKD2_k127_2526721_3
Catalyzes the reversible oxidation of malate to oxaloacetate
K00024
-
1.1.1.37
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341
316.0
View
HKD2_k127_2526721_4
Hydrogenase accessory protein HypB
K04652
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082
302.0
View
HKD2_k127_2526721_5
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides
K03118
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000002598
248.0
View
HKD2_k127_2526721_6
Fumarate hydratase (Fumerase)
K01677
-
4.2.1.2
0.000000000000000000000000000000000000000000000000000000005626
202.0
View
HKD2_k127_2526721_7
PFAM metal-dependent phosphohydrolase, HD sub domain
K06951
-
-
0.00000000000000000000000000000000000000000000000000009204
191.0
View
HKD2_k127_2526721_8
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
K03183
-
2.1.1.163,2.1.1.201
0.0000000000000000000000000000000000000000000000000007512
192.0
View
HKD2_k127_2526721_9
Probably plays a role in a hydrogenase nickel cofactor insertion step
K04651
-
-
0.00000000000000000000000000000000001942
140.0
View
HKD2_k127_2579122_0
Belongs to the IlvD Edd family
K01687
-
4.2.1.9
1.345e-224
713.0
View
HKD2_k127_2579122_1
Thiamine pyrophosphate enzyme, central domain
K01652
-
2.2.1.6
1.579e-223
706.0
View
HKD2_k127_2579122_10
Polysaccharide deacetylase
K22278
-
3.5.1.104
0.000000000000000000000000000000000000000000000000000000000000002525
227.0
View
HKD2_k127_2579122_11
ACT domain
K01653
-
2.2.1.6
0.000000000000000000000000000000000000000000000000000000003489
224.0
View
HKD2_k127_2579122_12
calcium- and calmodulin-responsive adenylate cyclase activity
K08372
-
-
0.00000000000000000000000000000000007317
148.0
View
HKD2_k127_2579122_13
calcium- and calmodulin-responsive adenylate cyclase activity
K08372
-
-
0.000000000000000000000000000002666
134.0
View
HKD2_k127_2579122_14
-
-
-
-
0.00000000000000005291
85.0
View
HKD2_k127_2579122_15
cell wall binding repeat
-
-
-
0.0000000000000166
88.0
View
HKD2_k127_2579122_16
cell wall anchor domain
-
-
-
0.00000002454
66.0
View
HKD2_k127_2579122_17
Pfam:N_methyl_2
-
-
-
0.0000009576
61.0
View
HKD2_k127_2579122_18
pilus assembly protein PilW
-
-
-
0.000003688
59.0
View
HKD2_k127_2579122_19
Transcriptional regulatory protein, C terminal
-
-
-
0.0001839
53.0
View
HKD2_k127_2579122_2
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K01703
-
4.2.1.33,4.2.1.35
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724
597.0
View
HKD2_k127_2579122_20
cyclic-guanylate-specific phosphodiesterase activity
-
-
-
0.0009014
46.0
View
HKD2_k127_2579122_3
PFAM Pyruvate carboxyltransferase
K02594
-
2.3.3.14
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249
525.0
View
HKD2_k127_2579122_4
Isocitrate/isopropylmalate dehydrogenase
K00030
-
1.1.1.41
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107
490.0
View
HKD2_k127_2579122_5
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K02434
GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564
6.3.5.6,6.3.5.7
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737
484.0
View
HKD2_k127_2579122_6
HD domain
K07814
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017
314.0
View
HKD2_k127_2579122_7
TipAS antibiotic-recognition domain
K21744
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066
301.0
View
HKD2_k127_2579122_8
Histone deacetylase domain
K04768
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035
305.0
View
HKD2_k127_2579122_9
Aconitase C-terminal domain
K01704
-
4.2.1.33,4.2.1.35
0.0000000000000000000000000000000000000000000000000000000000000000000002756
241.0
View
HKD2_k127_2679593_0
Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
K04077
-
-
2.466e-233
734.0
View
HKD2_k127_2679593_1
ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
K06942
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598
473.0
View
HKD2_k127_2679593_2
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K01409,K03070,K03789,K14742
GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004596,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006464,GO:0006473,GO:0006474,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008999,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0030312,GO:0031365,GO:0032991,GO:0034212,GO:0034470,GO:0034641,GO:0034660,GO:0036211,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051604,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564
2.3.1.128,2.3.1.234
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702
477.0
View
HKD2_k127_2679593_3
IMP dehydrogenase / GMP reductase domain
K00088
-
1.1.1.205
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128
352.0
View
HKD2_k127_2679593_4
glycosyl transferase group 1
-
-
-
0.000000000000000000000000000000000000000000001275
180.0
View
HKD2_k127_2679593_5
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K01409
-
2.3.1.234
0.00000000000000000000000000000000000000001152
171.0
View
HKD2_k127_2679593_6
Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K04078
-
-
0.00000000000000000000000000000000007597
137.0
View
HKD2_k127_2679593_7
Hydrolase, P-loop family
K06925
-
-
0.0000000000000000000000000000000002651
139.0
View
HKD2_k127_2679593_8
Uracil DNA glycosylase superfamily
-
-
-
0.00003749
48.0
View
HKD2_k127_2824665_0
Belongs to the CarB family
K01955
-
6.3.5.5
3.647e-204
645.0
View
HKD2_k127_2824665_1
Catalyzes the conversion of dihydroorotate to orotate
K17828
-
1.3.1.14
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149
400.0
View
HKD2_k127_2824665_2
Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
K01591
-
4.1.1.23
0.00000000000000000000000000000000000000000000000000000000000000000000001477
249.0
View
HKD2_k127_2824665_3
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
K02823
-
-
0.00000000000000000000000000000000000000000000000000000000001465
232.0
View
HKD2_k127_2824665_4
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K00762
-
2.4.2.10
0.00000000000000000000000000000000000000000000000001161
187.0
View
HKD2_k127_2824665_5
integration host factor
-
-
-
0.00000000000000000000000000005965
124.0
View
HKD2_k127_2824665_6
Essential for recycling GMP and indirectly, cGMP
K00942
-
2.7.4.8
0.0000000000000000000000000005334
115.0
View
HKD2_k127_2834980_0
transferase activity, transferring glycosyl groups
K20444
-
-
0.00000000000000000000000000000000000000002078
169.0
View
HKD2_k127_2967265_0
ABC-type transport system, involved in lipoprotein release, permease component
K02004
-
-
9.529e-261
837.0
View
HKD2_k127_2967265_1
GTP-binding protein TypA
K06207
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844
550.0
View
HKD2_k127_2967265_10
Copper binding proteins, plastocyanin/azurin family
-
-
-
0.00000000003734
74.0
View
HKD2_k127_2967265_2
PFAM LOR SDH bifunctional
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714
441.0
View
HKD2_k127_2967265_3
Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
K00765
-
2.4.2.17
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005
414.0
View
HKD2_k127_2967265_4
ABC-type antimicrobial peptide transport system, ATPase component
K02003
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108
353.0
View
HKD2_k127_2967265_5
PFAM Rubrerythrin
-
GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001381
278.0
View
HKD2_k127_2967265_6
Enoyl-(Acyl carrier protein) reductase
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000007001
248.0
View
HKD2_k127_2967265_7
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K07304
-
1.8.4.11
0.0000000000000000000000000000000000000000000000000531
183.0
View
HKD2_k127_2967265_8
PFAM Methionine sulfoxide reductase B
K07305
-
1.8.4.12
0.00000000000000000000000000000000000000000001618
175.0
View
HKD2_k127_2967265_9
Protein of unknown function (DUF1003)
-
-
-
0.0000000000000000000000000000003706
130.0
View
HKD2_k127_3138750_0
An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K12574
-
-
9.775e-207
658.0
View
HKD2_k127_3138750_1
Belongs to the peptidase M16 family
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155
369.0
View
HKD2_k127_3138750_2
Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K01714
-
4.3.3.7
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444
358.0
View
HKD2_k127_3138750_3
Belongs to the aspartokinase family
K00928
-
2.7.2.4
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377
335.0
View
HKD2_k127_3138750_4
Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
K00215
-
1.17.1.8
0.000000000000000000000000000000000000000000000000000000000000000000000000003395
261.0
View
HKD2_k127_3138750_5
HD domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000004602
226.0
View
HKD2_k127_3138750_6
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
K06153
-
3.6.1.27
0.000000000000000000000000000000000000000002024
165.0
View
HKD2_k127_3138750_7
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
K00962
-
2.7.7.8
0.0000000000000000000008904
97.0
View
HKD2_k127_3138750_8
FtsK SpoIIIE family
K03466
-
-
0.00002149
58.0
View
HKD2_k127_3175879_0
Cation transporting ATPase, C-terminus
K01531
-
3.6.3.2
9.39e-291
927.0
View
HKD2_k127_3175879_1
3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
K12573
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314
549.0
View
HKD2_k127_3175879_10
Transketolase, thiamine diphosphate binding domain
K00615
-
2.2.1.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701
323.0
View
HKD2_k127_3175879_11
OST-HTH/LOTUS domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932
298.0
View
HKD2_k127_3175879_12
Belongs to the peptidase S41A family
K03797
-
3.4.21.102
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005421
298.0
View
HKD2_k127_3175879_13
protein conserved in bacteria (DUF2179)
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000001383
258.0
View
HKD2_k127_3175879_14
SNARE associated Golgi protein
K03975
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
-
0.00000000000000000000000000000000000000000000000000000000000000000000000438
250.0
View
HKD2_k127_3175879_15
Part of the ABC transporter FtsEX involved in cellular division
K09811
-
-
0.0000000000000000000000000000000000000000000000000000000000000001926
231.0
View
HKD2_k127_3175879_16
Methyltransferase, chemotaxis proteins
K00575
-
2.1.1.80
0.0000000000000000000000000000000000000000000000000000000000004131
231.0
View
HKD2_k127_3175879_17
chemotaxis
K03406
-
-
0.0000000000000000000000000000000000000000000000000000000003451
218.0
View
HKD2_k127_3175879_18
Regulator of chromosome condensation (RCC1) repeat
-
-
-
0.0000000000000000000000000000000000000000000000000001672
208.0
View
HKD2_k127_3175879_19
Serine aminopeptidase, S33
-
-
-
0.00000000000000000000000000000000000000000000000000653
194.0
View
HKD2_k127_3175879_2
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
K02836
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022
451.0
View
HKD2_k127_3175879_20
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K03768
-
5.2.1.8
0.0000000000000000000000000000000000000000000000004479
180.0
View
HKD2_k127_3175879_21
PFAM Acetyltransferase (GNAT) family
K00657
-
2.3.1.57
0.000000000000000000000000000000000000000000000001754
184.0
View
HKD2_k127_3175879_22
the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
K03664
-
-
0.000000000000000000000000000000000000000000000002828
191.0
View
HKD2_k127_3175879_23
PHP domain protein
K04477
-
-
0.00000000000000000000000000000000000000000000002953
190.0
View
HKD2_k127_3175879_24
Type II/IV secretion system protein
-
-
-
0.0000000000000000000000000000000000000000000003365
183.0
View
HKD2_k127_3175879_25
Metal-dependent hydrolase
K07043
-
-
0.0000000000000000000000000000000000000004831
158.0
View
HKD2_k127_3175879_26
heat shock protein binding
-
-
-
0.000000000000000000000000000000000001312
154.0
View
HKD2_k127_3175879_27
-
-
-
-
0.00000000000000000000000000000000001072
140.0
View
HKD2_k127_3175879_28
Condensation domain
-
-
-
0.00000000000000000000000000000000005725
152.0
View
HKD2_k127_3175879_29
heat shock protein binding
-
-
-
0.000000000000000000000000000000006562
141.0
View
HKD2_k127_3175879_3
Two component signalling adaptor domain
K03407,K13490
GO:0003674,GO:0005488,GO:0005515,GO:0019904
2.7.13.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523
458.0
View
HKD2_k127_3175879_30
Phage derived protein Gp49-like (DUF891)
-
-
-
0.0000000000000000000000000000005791
139.0
View
HKD2_k127_3175879_31
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
K02658
-
-
0.000000000000000000000000000003286
124.0
View
HKD2_k127_3175879_32
catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
K03412
-
3.1.1.61,3.5.1.44
0.00000000000000000000000000785
111.0
View
HKD2_k127_3175879_33
RF-1 domain
-
-
-
0.000000000000000000000000196
110.0
View
HKD2_k127_3175879_34
Two component signalling adaptor domain
K03408
-
-
0.0000000000000000001208
97.0
View
HKD2_k127_3175879_35
peptidase U32
K08303
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464
-
0.0000000000000000002438
90.0
View
HKD2_k127_3175879_36
Transcriptional regulator PadR-like family
-
-
-
0.000000000000000171
83.0
View
HKD2_k127_3175879_37
Two component signalling adaptor domain
K03408
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009453,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0042333,GO:0044424,GO:0044444,GO:0044464,GO:0050896
-
0.0000000000000003167
90.0
View
HKD2_k127_3175879_38
heat shock protein binding
K05516
-
-
0.000000000000005817
84.0
View
HKD2_k127_3175879_39
4Fe-4S single cluster domain of Ferredoxin I
K05337
-
-
0.00000000000005592
73.0
View
HKD2_k127_3175879_4
M42 glutamyl aminopeptidase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735
432.0
View
HKD2_k127_3175879_40
-
-
-
-
0.0000000000001856
85.0
View
HKD2_k127_3175879_42
Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K02652
-
-
0.00001528
57.0
View
HKD2_k127_3175879_5
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
K03070
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171
410.0
View
HKD2_k127_3175879_6
beta-propeller repeat
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102
387.0
View
HKD2_k127_3175879_7
Transketolase, pyridine binding domain protein
K00615
-
2.2.1.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614
380.0
View
HKD2_k127_3175879_8
cell division ATP-binding protein FtsE
K09812
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082
355.0
View
HKD2_k127_3175879_9
metal-dependent phosphohydrolase HD region
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595
333.0
View
HKD2_k127_318185_0
Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K00761
-
2.4.2.9
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101
305.0
View
HKD2_k127_318185_1
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
K02111
-
3.6.3.14
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000144
277.0
View
HKD2_k127_318185_2
Glycosyl transferase family 4
K02851
GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576
2.7.8.33,2.7.8.35
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000116
285.0
View
HKD2_k127_318185_3
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K00600
-
2.1.2.1
0.000000000000000000000000000000000000000000000000000000000000000000000000002604
256.0
View
HKD2_k127_318185_4
PFAM Cytidine and deoxycytidylate deaminase zinc-binding region
K01493
-
3.5.4.12
0.0000000000000000000000000000000000000000000000000000000000000001962
224.0
View
HKD2_k127_318185_5
it plays a direct role in the translocation of protons across the membrane
K02108
-
-
0.00000000000000000000000000000000000000000000000000002625
203.0
View
HKD2_k127_318185_6
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K02109
-
-
0.000000000000000000000000000000000006949
143.0
View
HKD2_k127_318185_7
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K02113
-
-
0.0000000000000000000000007316
113.0
View
HKD2_k127_318185_8
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
-
-
-
0.000000000000000008304
86.0
View
HKD2_k127_3263738_0
Belongs to the transketolase family
K00615
-
2.2.1.1
3.448e-196
630.0
View
HKD2_k127_3263738_1
Nickel-dependent hydrogenase
K06281
-
1.12.99.6
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202
574.0
View
HKD2_k127_3263738_10
Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K00231
-
1.3.3.15,1.3.3.4
0.0000000000000000001231
93.0
View
HKD2_k127_3263738_11
Acetyl-coenzyme A synthetase N-terminus
K01895
-
6.2.1.1
0.0000000000000000009838
87.0
View
HKD2_k127_3263738_2
Elongator protein 3, MiaB family, Radical SAM
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086
496.0
View
HKD2_k127_3263738_3
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K01599,K14080
GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
2.1.1.246,4.1.1.37
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606
430.0
View
HKD2_k127_3263738_4
NiFe/NiFeSe hydrogenase small subunit C-terminal
K06282
-
1.12.99.6
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769
396.0
View
HKD2_k127_3263738_5
Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K00231
-
1.3.3.15,1.3.3.4
0.00000000000000000000000000000000000000000000000000000000000000000000000000005934
271.0
View
HKD2_k127_3263738_6
Cytochrome b/b6/petB
K03620
-
-
0.00000000000000000000000000000000000000000000000000000000000007342
220.0
View
HKD2_k127_3263738_7
Inositol monophosphatase family
K01092
GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616
3.1.3.25
0.00000000000000000000000000000000000000000000000001208
191.0
View
HKD2_k127_3263738_8
Catalyzes the ferrous insertion into protoporphyrin IX
K01772
GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
4.99.1.1,4.99.1.9
0.00000000000000000000000000000000002912
147.0
View
HKD2_k127_3263738_9
hydrogenase maturation protease
K03605
-
-
0.00000000000000000000000001285
118.0
View
HKD2_k127_3325752_0
The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
K01696
-
4.2.1.20
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182
469.0
View
HKD2_k127_3325752_1
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K01657,K13503
-
4.1.3.27
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568
477.0
View
HKD2_k127_3325752_10
Pyridoxamine 5'-phosphate oxidase
K07005
-
-
0.000000000000000000000000000000002476
139.0
View
HKD2_k127_3325752_11
ArsR family transcriptional regulator
-
GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141
-
0.000000000000000000000000001431
116.0
View
HKD2_k127_3325752_12
Phosphoribosyl-ATP pyrophosphohydrolase
K01523
-
3.6.1.31
0.00000000000000000002854
94.0
View
HKD2_k127_3325752_13
Zn-dependent protease with chaperone function
K03799
-
-
0.000000000009713
77.0
View
HKD2_k127_3325752_2
Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K00766
-
2.4.2.18
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096
449.0
View
HKD2_k127_3325752_3
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
K02500
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841
354.0
View
HKD2_k127_3325752_4
1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K01814
-
5.3.1.16
0.00000000000000000000000000000000000000000000000000000000000000000007043
238.0
View
HKD2_k127_3325752_5
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K02501
-
-
0.000000000000000000000000000000000000000000000000000000000000000000111
236.0
View
HKD2_k127_3325752_6
Belongs to the TrpF family
K01817
-
5.3.1.24
0.000000000000000000000000000000000000000007984
173.0
View
HKD2_k127_3325752_7
Histidine biosynthesis bifunctional protein hisIE
K01496,K11755
-
3.5.4.19,3.6.1.31
0.0000000000000000000000000000000000000001493
154.0
View
HKD2_k127_3325752_8
Belongs to the TrpC family
K01609,K13498
GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831
4.1.1.48,5.3.1.24
0.0000000000000000000000000000000000000001597
167.0
View
HKD2_k127_3325752_9
Protein of unknown function (DUF1648)
-
-
-
0.0000000000000000000000000000000000000727
154.0
View
HKD2_k127_340133_0
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K01756
GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
4.3.2.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000732
538.0
View
HKD2_k127_340133_1
Pyruvate phosphate dikinase, PEP/pyruvate binding domain
K01006
-
2.7.9.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248
455.0
View
HKD2_k127_340133_10
Bacteriocin-protection, YdeI or OmpD-Associated
-
-
-
0.00000000000000000000000000000000000000004495
165.0
View
HKD2_k127_340133_11
PadR family transcriptional regulator
K10947
-
-
0.000000000000000000000000000000000000001381
150.0
View
HKD2_k127_340133_13
Peptidoglycan-binding domain 1 protein
-
-
-
0.000000000000000000000004533
108.0
View
HKD2_k127_340133_14
Transcriptional regulator
-
-
-
0.00000000000000000004792
98.0
View
HKD2_k127_340133_15
Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K07275,K16079
-
-
0.0000000000000000003095
95.0
View
HKD2_k127_340133_16
Excalibur calcium-binding domain
-
-
-
0.00000000000002521
79.0
View
HKD2_k127_340133_17
membrane
-
-
-
0.0000000000001802
83.0
View
HKD2_k127_340133_18
The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
K03076
-
-
0.000000000005053
78.0
View
HKD2_k127_340133_2
GTP-binding protein TypA
K06207
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299
391.0
View
HKD2_k127_340133_20
Bacterial regulatory proteins, tetR family
-
-
-
0.000000006812
66.0
View
HKD2_k127_340133_21
Kinase domain
K12132
-
2.7.11.1
0.00000001294
64.0
View
HKD2_k127_340133_22
-
-
-
-
0.000006541
53.0
View
HKD2_k127_340133_23
Phospholipase_D-nuclease N-terminal
-
-
-
0.0001427
48.0
View
HKD2_k127_340133_3
TIGRFAM cation diffusion facilitator family transporter
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225
341.0
View
HKD2_k127_340133_4
Aldo/keto reductase family
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408
323.0
View
HKD2_k127_340133_5
Putative sensor
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003154
289.0
View
HKD2_k127_340133_6
Acyltransferase family
-
-
-
0.00000000000000000000000000000000000000000000000000000000000004088
233.0
View
HKD2_k127_340133_7
WG containing repeat
-
-
-
0.0000000000000000000000000000000000000000000000005526
196.0
View
HKD2_k127_340133_8
SMART Elongator protein 3 MiaB NifB
K22226
-
-
0.000000000000000000000000000000000000000000000002782
195.0
View
HKD2_k127_340133_9
Psort location Cytoplasmic, score
-
-
-
0.00000000000000000000000000000000000000000000002632
181.0
View
HKD2_k127_3858650_0
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K03639
-
4.1.99.22
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366
394.0
View
HKD2_k127_3858650_1
Cysteine desulfurase
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749
351.0
View
HKD2_k127_3858650_10
TIGRFAM molybdenum cofactor synthesis
-
-
-
0.0000000000000000000000000000000000000000001404
172.0
View
HKD2_k127_3858650_11
Bacterial extracellular solute-binding protein
K05772
-
-
0.0000000000000000000000000000000000000005865
159.0
View
HKD2_k127_3858650_12
molybdopterin-guanine dinucleotide biosynthesis protein
K03753
-
-
0.000000000000000000000000000000000000006654
151.0
View
HKD2_k127_3858650_13
-
-
-
-
0.000003042
59.0
View
HKD2_k127_3858650_14
TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit
K03620
-
-
0.000191
50.0
View
HKD2_k127_3858650_2
MoeA N-terminal region (domain I and II)
K03750
-
2.10.1.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283
343.0
View
HKD2_k127_3858650_3
Bacterial extracellular solute-binding protein
K05772
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000006618
277.0
View
HKD2_k127_3858650_4
Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072
-
3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55
0.00000000000000000000000000000000000000000000000000000000000000000000000395
258.0
View
HKD2_k127_3858650_5
Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K02379
-
-
0.000000000000000000000000000000000000000000000000000000000000000865
237.0
View
HKD2_k127_3858650_6
LysR substrate binding domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000001846
226.0
View
HKD2_k127_3858650_7
MOSC domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000009577
212.0
View
HKD2_k127_3858650_8
PFAM binding-protein-dependent transport systems inner membrane component
K05773
-
-
0.000000000000000000000000000000000000000000000000000000001593
210.0
View
HKD2_k127_3858650_9
Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
K03637
-
4.6.1.17
0.000000000000000000000000000000000000000000000000000003385
194.0
View
HKD2_k127_3904148_0
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K01872
-
6.1.1.7
1.651e-312
979.0
View
HKD2_k127_3904148_1
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K01876
-
6.1.1.12
3.235e-219
696.0
View
HKD2_k127_3904148_10
RNA polymerase sigma-70 factor, sigma-B F G subfamily
K03090
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347
312.0
View
HKD2_k127_3904148_11
Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K01735
-
4.2.3.4
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000102
307.0
View
HKD2_k127_3904148_12
PFAM peptidase M24
K01262,K01271
-
3.4.11.9,3.4.13.9
0.00000000000000000000000000000000000000000000000000000000000000000000000000000008962
285.0
View
HKD2_k127_3904148_13
Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K07082
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000008136
258.0
View
HKD2_k127_3904148_14
AAA domain, putative AbiEii toxin, Type IV TA system
K01990
-
-
0.000000000000000000000000000000000000000000000000000000000000000341
232.0
View
HKD2_k127_3904148_15
Type IV pilus assembly protein PilM;
K02662
-
-
0.00000000000000000000000000000000000000000000000000000000000002883
228.0
View
HKD2_k127_3904148_16
Conserved hypothetical ATP binding protein
K06945
-
-
0.00000000000000000000000000000000000000000000000000000000007697
209.0
View
HKD2_k127_3904148_17
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K00014
-
1.1.1.25
0.000000000000000000000000000000000000000000000000000000004195
210.0
View
HKD2_k127_3904148_18
Catalyzes a trans-dehydration via an enolate intermediate
K03786
-
4.2.1.10
0.00000000000000000000000000000000000000000000000000005062
190.0
View
HKD2_k127_3904148_19
AI-2E family transporter
-
-
-
0.0000000000000000000000000000000000000000000000000189
202.0
View
HKD2_k127_3904148_2
General secretory system II, protein E domain protein
K02652
-
-
4.439e-197
635.0
View
HKD2_k127_3904148_20
Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K02654
-
3.4.23.43
0.00000000000000000000000000000000000000000000005515
181.0
View
HKD2_k127_3904148_21
HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668
K07015
-
-
0.000000000000000000000000000000000000001425
161.0
View
HKD2_k127_3904148_22
Domain of unknown function (DUF4388)
-
-
-
0.00000000000000000000000000000000000000491
167.0
View
HKD2_k127_3904148_23
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K00891
-
2.7.1.71
0.0000000000000000000000000000000004702
140.0
View
HKD2_k127_3904148_24
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K07447
GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360
-
0.000000000000000000000000000000003303
144.0
View
HKD2_k127_3904148_25
PFAM Roadblock LC7 family protein
K07131
-
-
0.0000000000000000000000000000001231
134.0
View
HKD2_k127_3904148_26
Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K06199
GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425
-
0.000000000000000000000001388
107.0
View
HKD2_k127_3904148_27
-
K04757
-
2.7.11.1
0.0000000000000000002804
93.0
View
HKD2_k127_3904148_28
-
-
-
-
0.0000000000003713
78.0
View
HKD2_k127_3904148_29
prepilin-type N-terminal cleavage methylation domain
K02456,K02650
-
-
0.00000000002573
76.0
View
HKD2_k127_3904148_3
General secretory system II, protein E domain protein
K02652
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578
582.0
View
HKD2_k127_3904148_30
Prokaryotic N-terminal methylation motif
-
-
-
0.000001543
62.0
View
HKD2_k127_3904148_31
PFAM Fimbrial assembly family protein
K02663
-
-
0.000002287
57.0
View
HKD2_k127_3904148_32
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K02356
-
-
0.000003682
48.0
View
HKD2_k127_3904148_33
PFAM Pilus assembly protein PilO
K02664
-
-
0.000184
51.0
View
HKD2_k127_3904148_34
Bacterial protein of unknown function (DUF948)
-
-
-
0.0007236
47.0
View
HKD2_k127_3904148_4
PFAM AAA ATPase central domain protein
K07478
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421
533.0
View
HKD2_k127_3904148_5
histidyl-tRNA synthetase
K01892
-
6.1.1.21
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205
476.0
View
HKD2_k127_3904148_6
Type II/IV secretion system protein
K02669
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421
446.0
View
HKD2_k127_3904148_7
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K01736
-
4.2.3.5
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431
385.0
View
HKD2_k127_3904148_8
COG COG1459 Type II secretory pathway component PulF Cell motility and secretion Intracellular trafficking and secretion
K02653
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803
349.0
View
HKD2_k127_3904148_9
PFAM AMP-dependent synthetase and ligase
K00666
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859
318.0
View
HKD2_k127_3951125_0
PFAM Uncharacterised protein family UPF0182
K09118
-
-
8.632e-195
623.0
View
HKD2_k127_3951125_1
Alanine-glyoxylate amino-transferase
K05825
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987
539.0
View
HKD2_k127_3951125_10
phosphoribosyltransferase
K07100
-
-
0.00000000000000000000000000000000000000000000001586
179.0
View
HKD2_k127_3951125_11
Polysaccharide deacetylase
K01181,K22278
-
3.2.1.8,3.5.1.104
0.00000000000000000000000000000000000000000001097
180.0
View
HKD2_k127_3951125_12
Acetyltransferase (GNAT) family
-
-
-
0.000000000000000000000000000000000000000001238
164.0
View
HKD2_k127_3951125_13
Haloacid dehalogenase domain protein hydrolase, type 3
-
-
-
0.00000000000000000000000000000000000000007604
169.0
View
HKD2_k127_3951125_14
YbaK prolyl-tRNA synthetase associated region
-
-
-
0.00000000000000000000000002411
116.0
View
HKD2_k127_3951125_15
Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K01934
-
6.3.3.2
0.0000000000000000000000001678
113.0
View
HKD2_k127_3951125_16
-
-
-
-
0.000000000000000004013
94.0
View
HKD2_k127_3951125_17
Redoxin
-
-
-
0.00000000003892
69.0
View
HKD2_k127_3951125_18
Acetyltransferase (GNAT) domain
-
-
-
0.000000000235
69.0
View
HKD2_k127_3951125_2
Magnesium transporter
K06213
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768
508.0
View
HKD2_k127_3951125_20
PFAM PRC-barrel domain
-
-
-
0.00000001901
64.0
View
HKD2_k127_3951125_3
Metal ion transporter, metal ion (Mn2 Fe2 ) transporter (Nramp) family
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733
451.0
View
HKD2_k127_3951125_4
Belongs to the D-alanine--D-alanine ligase family
K01921
-
6.3.2.4
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668
311.0
View
HKD2_k127_3951125_5
serine threonine protein kinase
K08884,K12132
GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576
2.7.11.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801
305.0
View
HKD2_k127_3951125_6
acetyltransferase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000004594
276.0
View
HKD2_k127_3951125_7
Galactose-1-phosphate uridyl transferase, N-terminal domain
K00965
-
2.7.7.12
0.000000000000000000000000000000000000000000000000000000000000004651
229.0
View
HKD2_k127_3951125_8
phosphoprotein phosphatase activity
-
-
-
0.0000000000000000000000000000000000000000000000000000000001221
216.0
View
HKD2_k127_3951125_9
ABC-type nitrate sulfonate bicarbonate transport
K02051
-
-
0.000000000000000000000000000000000000000000000004619
185.0
View
HKD2_k127_3980121_0
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K02469
-
5.99.1.3
0.0
1120.0
View
HKD2_k127_3980121_1
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K02470
-
5.99.1.3
4.21e-260
815.0
View
HKD2_k127_3980121_10
it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K03629
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815
323.0
View
HKD2_k127_3980121_11
MacB-like periplasmic core domain
K02004
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334
320.0
View
HKD2_k127_3980121_12
Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
K02338
-
2.7.7.7
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278
308.0
View
HKD2_k127_3980121_13
Belongs to the ParB family
K03497
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000001394
280.0
View
HKD2_k127_3980121_14
ABC transporter
K02003
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000001447
283.0
View
HKD2_k127_3980121_15
PFAM NADPH-dependent FMN reductase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000189
257.0
View
HKD2_k127_3980121_16
Serine dehydratase alpha chain
K01752
-
4.3.1.17
0.0000000000000000000000000000000000000000000000000000000000000000008745
238.0
View
HKD2_k127_3980121_17
Belongs to the peptidase S1C family
K04771
-
3.4.21.107
0.0000000000000000000000000000000000000000000000000000000000000009513
235.0
View
HKD2_k127_3980121_18
TIGRFAM L-serine dehydratase, iron-sulfur-dependent, beta subunit
K01752
-
4.3.1.17
0.00000000000000000000000000000000000000000000000000000000000001411
224.0
View
HKD2_k127_3980121_19
PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
-
-
-
0.000000000000000000000000000000000000000000000000000000001551
211.0
View
HKD2_k127_3980121_2
ATPase, P-type (transporting), HAD superfamily, subfamily IC
K01537
-
3.6.3.8
1.623e-222
722.0
View
HKD2_k127_3980121_20
R3H domain
K06346
-
-
0.000000000000000000000000000000000000000000000000000000006348
207.0
View
HKD2_k127_3980121_21
PD-(D/E)XK nuclease superfamily
-
-
-
0.0000000000000000000000000000000000000000000000000000681
214.0
View
HKD2_k127_3980121_22
PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein
-
-
-
0.0000000000000000000000000000000000000000000000003815
190.0
View
HKD2_k127_3980121_23
Rubrerythrin
-
-
-
0.0000000000000000000000000000000000000000000000007115
181.0
View
HKD2_k127_3980121_24
IA, variant 3
K06019
-
3.6.1.1
0.00000000000000000000000000000000000000000000001517
183.0
View
HKD2_k127_3980121_25
Membrane protein insertase, YidC Oxa1 family
K03217
-
-
0.00000000000000000000000000000000000000000001404
173.0
View
HKD2_k127_3980121_26
PFAM Uncharacterised protein family UPF0047
-
-
-
0.0000000000000000000000000000000000000000001591
162.0
View
HKD2_k127_3980121_27
Bifunctional nuclease
K08999
GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944
-
0.000000000000000000000000000000000000003053
151.0
View
HKD2_k127_3980121_28
Major facilitator superfamily
-
-
-
0.000000000000000000000000000000000000005906
162.0
View
HKD2_k127_3980121_29
Histidine kinase
K02484
-
2.7.13.3
0.000000000000000000000000000000000000761
158.0
View
HKD2_k127_3980121_3
DnaQ family exonuclease DinG family helicase
K03722
-
3.6.4.12
8.65e-216
705.0
View
HKD2_k127_3980121_30
Histidine kinase
-
-
-
0.000000000000000000000000000000000007486
154.0
View
HKD2_k127_3980121_31
Specifically methylates the N7 position of a guanine in 16S rRNA
K03501
-
2.1.1.170
0.000000000000000000000000000000002849
138.0
View
HKD2_k127_3980121_33
Could be involved in insertion of integral membrane proteins into the membrane
K08998
-
-
0.00000000000000000000000001782
113.0
View
HKD2_k127_3980121_34
WYL domain
K13572,K13573
GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944
-
0.0000000000000000000000001156
125.0
View
HKD2_k127_3980121_35
cyclic nucleotide-binding
K01420,K21563
-
-
0.0000000000000000000000003406
115.0
View
HKD2_k127_3980121_36
overlaps another CDS with the same product name
K13573
GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944
-
0.000000000000000001926
96.0
View
HKD2_k127_3980121_37
FeoA
-
-
-
0.00000000000000004614
84.0
View
HKD2_k127_3980121_38
Belongs to the bacterial ribosomal protein bL34 family
K02914
-
-
0.00000000000003361
77.0
View
HKD2_k127_3980121_39
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
K03536
GO:0008150,GO:0040007
3.1.26.5
0.000000000001429
72.0
View
HKD2_k127_3980121_4
transporter of a GTP-driven Fe(2 ) uptake system
K04759
-
-
1.779e-207
661.0
View
HKD2_k127_3980121_40
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K03585
-
-
0.000000000355
72.0
View
HKD2_k127_3980121_41
-
-
-
-
0.000000005266
66.0
View
HKD2_k127_3980121_42
Protein of unknown function (DUF721)
-
-
-
0.0004258
52.0
View
HKD2_k127_3980121_43
-
-
-
-
0.0004688
46.0
View
HKD2_k127_3980121_44
gas vesicle protein
-
-
-
0.0007585
46.0
View
HKD2_k127_3980121_5
Bacterial dnaA protein helix-turn-helix domain
K02313
GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517
466.0
View
HKD2_k127_3980121_6
PD-(D/E)XK nuclease superfamily
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206
461.0
View
HKD2_k127_3980121_7
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
K06941
-
2.1.1.192
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452
393.0
View
HKD2_k127_3980121_8
CobQ CobB MinD ParA nucleotide binding domain
K03496
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425
339.0
View
HKD2_k127_3980121_9
Belongs to the D-alanine--D-alanine ligase family
K01921
-
6.3.2.4
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615
329.0
View
HKD2_k127_401030_0
SMART Elongator protein 3 MiaB NifB
K04034
-
1.21.98.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202
554.0
View
HKD2_k127_401030_1
Chemotaxis protein CheA
K03407
-
2.7.13.3
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043
461.0
View
HKD2_k127_401030_10
Peptidoglycan binding domain
-
-
-
0.00000000000000000000000000000000000000000299
166.0
View
HKD2_k127_401030_11
NLP P60 protein
K21471
-
-
0.0000000000000000000000000000000000000002298
166.0
View
HKD2_k127_401030_12
endoribonuclease L-PSP
-
-
-
0.000000000000000000000000000000000000000306
153.0
View
HKD2_k127_401030_13
Chemotaxis protein CheC
K03410
-
-
0.000000000000000000000000000000000000004274
155.0
View
HKD2_k127_401030_14
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
K03411
-
3.5.1.44
0.00000000000000000000000000000005361
130.0
View
HKD2_k127_401030_15
COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
-
-
-
0.00000000000000000000000002986
120.0
View
HKD2_k127_401030_16
VanZ like family
-
-
-
0.000000000000000004375
91.0
View
HKD2_k127_401030_2
glycosyl transferase, family 51
K05366
-
2.4.1.129,3.4.16.4
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957
443.0
View
HKD2_k127_401030_3
Type II/IV secretion system protein
K02669
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621
403.0
View
HKD2_k127_401030_4
4Fe-4S ferredoxin, iron-sulfur binding
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083
317.0
View
HKD2_k127_401030_5
catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
K03412
-
3.1.1.61,3.5.1.44
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004149
286.0
View
HKD2_k127_401030_6
chemotaxis
K03406
-
-
0.00000000000000000000000000000000000000000000000000000005442
213.0
View
HKD2_k127_401030_7
diguanylate cyclase
-
-
-
0.0000000000000000000000000000000000000000000000000008647
202.0
View
HKD2_k127_401030_8
cheY-homologous receiver domain
K03413
-
-
0.0000000000000000000000000000000000000000001814
162.0
View
HKD2_k127_401030_9
NapC/NirT cytochrome c family, N-terminal region
-
-
-
0.0000000000000000000000000000000000000000003365
180.0
View
HKD2_k127_4065125_0
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K01895
-
6.2.1.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655
492.0
View
HKD2_k127_4065125_1
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
K03601
-
3.1.11.6
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777
402.0
View
HKD2_k127_4065125_2
RecQ zinc-binding
K03654
-
3.6.4.12
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617
373.0
View
HKD2_k127_4065125_3
protein conserved in bacteria
-
-
-
0.00000000000000000000000000000000000000000000000001832
191.0
View
HKD2_k127_4065125_4
Histidine triad domain protein
K02503
-
-
0.00000000000000000000000000000000004576
143.0
View
HKD2_k127_4065125_5
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
K03602
-
3.1.11.6
0.0000000000001338
74.0
View
HKD2_k127_4077086_0
RmlD substrate binding domain
K01784
-
5.1.3.2
0.0000000000000000000000000000000000000000000000000000000000000000000005102
246.0
View
HKD2_k127_4077086_1
Glycosyl transferases group 1
-
-
-
0.000000000000000000000000000000000000000000000000001154
198.0
View
HKD2_k127_4077086_2
transferase activity, transferring glycosyl groups
-
-
-
0.0000000000000000000000000000000000000000000003786
192.0
View
HKD2_k127_4077086_3
Acyltransferase
-
-
-
0.0000000000009807
81.0
View
HKD2_k127_423417_0
ATPases associated with a variety of cellular activities
K02056
-
3.6.3.17
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528
557.0
View
HKD2_k127_423417_1
Belongs to the AlaDH PNT family
K00259
-
1.4.1.1
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067
507.0
View
HKD2_k127_423417_2
Belongs to the 'phage' integrase family. XerC subfamily
K04763
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166
331.0
View
HKD2_k127_423417_3
PFAM Branched-chain amino acid transport system permease component
K02057
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008064
293.0
View
HKD2_k127_423417_4
ABC transporter substrate-binding protein PnrA-like
K02058,K07335
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001157
290.0
View
HKD2_k127_423417_5
Belongs to the binding-protein-dependent transport system permease family
K02057
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000001959
269.0
View
HKD2_k127_423417_6
Acetyltransferase (GNAT) domain
-
-
-
0.0000000000000000000000000454
121.0
View
HKD2_k127_423417_7
Protein of unknown function (DUF3866)
-
-
-
0.00000000000000002244
85.0
View
HKD2_k127_4255174_0
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K03531
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038
459.0
View
HKD2_k127_4255174_1
to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K01928
-
6.3.2.13
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953
442.0
View
HKD2_k127_4255174_10
Cell wall formation
K00075
-
1.3.1.98
0.000000000000000000000000000000000000000000000000000000000000000000000000000001365
272.0
View
HKD2_k127_4255174_11
Cell division protein FtsQ
K03589
-
-
0.00000000000000000000000001021
122.0
View
HKD2_k127_4255174_12
ErfK YbiS YcfS YnhG family protein
-
-
-
0.00000000000000000001759
103.0
View
HKD2_k127_4255174_2
Belongs to the MurCDEF family
K01924
-
6.3.2.8
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477
424.0
View
HKD2_k127_4255174_3
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
K03438
-
2.1.1.199
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189
384.0
View
HKD2_k127_4255174_4
PASTA domain
K03587
-
3.4.16.4
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673
394.0
View
HKD2_k127_4255174_5
First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K01000
-
2.7.8.13
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413
357.0
View
HKD2_k127_4255174_6
Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
K01929
-
6.3.2.10
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213
357.0
View
HKD2_k127_4255174_7
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K01925
-
6.3.2.9
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061
350.0
View
HKD2_k127_4255174_8
Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K02563
-
2.4.1.227
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009862
296.0
View
HKD2_k127_4255174_9
Belongs to the SEDS family
K03588
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002072
292.0
View
HKD2_k127_4269808_0
Putative glucoamylase
K13688
-
-
0.0
2441.0
View
HKD2_k127_4269808_1
TIGRFAM Ammonium transporter
K03320
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499
587.0
View
HKD2_k127_4269808_2
Belongs to the P(II) protein family
K04751,K04752
-
-
0.00000000000000000000000000000002772
137.0
View
HKD2_k127_4269808_3
COG0607 Rhodanese-related sulfurtransferase
K03972
-
-
0.00000000000000131
83.0
View
HKD2_k127_4269808_4
alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K06196
-
-
0.000000008316
59.0
View
HKD2_k127_4359435_0
Belongs to the TPP enzyme family
K01652
-
2.2.1.6
1.408e-214
689.0
View
HKD2_k127_4359435_1
DegT/DnrJ/EryC1/StrS aminotransferase family
K12452
-
1.17.1.1
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429
595.0
View
HKD2_k127_4359435_10
Glycosyl transferase family 2
K00721
-
2.4.1.83
0.000000000000000000000000000000000000000000000000000000000000000000007947
241.0
View
HKD2_k127_4359435_2
PFAM aminotransferase class-III
K01845
-
5.4.3.8
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204
574.0
View
HKD2_k127_4359435_3
NeuB family
K01654
-
2.5.1.56
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768
577.0
View
HKD2_k127_4359435_4
PFAM Glycosyl transferase family 2
K20534
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527
401.0
View
HKD2_k127_4359435_5
CDP-glucose 4,6-dehydratase
K01709
-
4.2.1.45
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831
394.0
View
HKD2_k127_4359435_6
Glucose-1-phosphate cytidylyltransferase
K00978
-
2.7.7.33
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117
384.0
View
HKD2_k127_4359435_7
UTP-glucose-1-phosphate uridylyltransferase
K00963
-
2.7.7.9
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000013
295.0
View
HKD2_k127_4359435_8
Methyltransferase FkbM domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001272
299.0
View
HKD2_k127_4359435_9
ADP-glyceromanno-heptose 6-epimerase activity
K01710,K01784
-
4.2.1.46,5.1.3.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007854
293.0
View
HKD2_k127_4370597_0
amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
K01873
-
6.1.1.9
0.0
1030.0
View
HKD2_k127_4370597_1
Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K00012
-
1.1.1.22
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526
411.0
View
HKD2_k127_4370597_10
calcium- and calmodulin-responsive adenylate cyclase activity
K08372
-
-
0.000000000000000000000000000001517
141.0
View
HKD2_k127_4370597_11
transferase activity, transferring glycosyl groups
-
-
-
0.00000000000000000000000000003969
133.0
View
HKD2_k127_4370597_12
PFAM Polysaccharide biosynthesis protein
-
-
-
0.000000000000000002681
99.0
View
HKD2_k127_4370597_13
Belongs to the phosphoglycerate mutase family
K15634
-
5.4.2.12
0.0000000000000007341
85.0
View
HKD2_k127_4370597_14
Belongs to the glycosyl hydrolase 43 family
-
-
-
0.000001235
62.0
View
HKD2_k127_4370597_2
Polysaccharide biosynthesis protein
K01784,K08679
-
5.1.3.2,5.1.3.6
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533
331.0
View
HKD2_k127_4370597_3
Bifunctional protein
K11754
-
6.3.2.12,6.3.2.17
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008744
292.0
View
HKD2_k127_4370597_4
transferase activity, transferring glycosyl groups
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000353
239.0
View
HKD2_k127_4370597_5
Chain length determinant protein
-
-
-
0.000000000000000000000000000000000000000000000000000004093
210.0
View
HKD2_k127_4370597_6
Glycosyl transferases group 1
-
-
-
0.00000000000000000000000000000000000000001835
173.0
View
HKD2_k127_4370597_7
Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
K01689
-
4.2.1.11
0.0000000000000000000000000000000000004729
154.0
View
HKD2_k127_4370597_8
ligase activity
-
-
-
0.0000000000000000000000000000000007138
144.0
View
HKD2_k127_4370597_9
Glycosyl transferases group 1
-
-
-
0.000000000000000000000000000000001616
143.0
View
HKD2_k127_4374855_0
Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
K02117
-
3.6.3.14,3.6.3.15
5.626e-244
767.0
View
HKD2_k127_4374855_1
Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
K02118
-
-
1.163e-222
698.0
View
HKD2_k127_4374855_2
metallopeptidase activity
K03568
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054
515.0
View
HKD2_k127_4374855_3
Putative modulator of DNA gyrase
K03592
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000002183
277.0
View
HKD2_k127_4374855_4
Histidine kinase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000008484
238.0
View
HKD2_k127_4374855_5
Produces ATP from ADP in the presence of a proton gradient across the membrane
K02120
-
-
0.0000000000000000000000000000000000000000000000001377
184.0
View
HKD2_k127_4374855_6
NLP P60 protein
K21471
-
-
0.000000000000000000000000000000000000000003476
173.0
View
HKD2_k127_4374855_7
Produces ATP from ADP in the presence of a proton gradient across the membrane
K02122
-
-
0.0000003484
56.0
View
HKD2_k127_4374855_8
subunit c
K02119
-
-
0.00007796
47.0
View
HKD2_k127_4565319_0
Uracil-DNA glycosylase, family 4
K21929
-
3.2.2.27
0.000000000000000000000000000000000000000000000000000000000008079
221.0
View
HKD2_k127_4565319_1
Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit
K02118
-
-
0.0000000000000000000000000000000000000000000000000000002687
196.0
View
HKD2_k127_4565319_2
Produces ATP from ADP in the presence of a proton gradient across the membrane
K02120
-
-
0.000000000000000000000000000000000000000000000000001093
190.0
View
HKD2_k127_4565319_3
Putative TM nitroreductase
-
-
-
0.00000000000000000000000000000000000000001564
163.0
View
HKD2_k127_4642278_0
Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
K00179
-
1.2.7.8
3.233e-197
637.0
View
HKD2_k127_4642278_1
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
K16881
-
2.7.7.13,5.4.2.8
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035
614.0
View
HKD2_k127_4642278_10
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K00282
-
1.4.4.2
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617
439.0
View
HKD2_k127_4642278_11
pfam ammecr1
K06990,K09141
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394
384.0
View
HKD2_k127_4642278_12
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K00791
-
2.5.1.75
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142
314.0
View
HKD2_k127_4642278_13
The glycine cleavage system catalyzes the degradation of glycine
K00605
-
2.1.2.10
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873
324.0
View
HKD2_k127_4642278_14
histidine kinase DNA gyrase B
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379
294.0
View
HKD2_k127_4642278_15
PFAM Extracellular ligand-binding receptor
K01999
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009294
292.0
View
HKD2_k127_4642278_16
Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
K01778
-
5.1.1.7
0.000000000000000000000000000000000000000000000000000000000000000000000000000000001392
283.0
View
HKD2_k127_4642278_17
PFAM Extracellular ligand-binding receptor
K01999
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000001452
286.0
View
HKD2_k127_4642278_18
TrkA-N domain
K10716
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000002446
276.0
View
HKD2_k127_4642278_19
ABC transporter
K01995
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000006541
272.0
View
HKD2_k127_4642278_2
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K00283
-
1.4.4.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774
571.0
View
HKD2_k127_4642278_20
Belongs to the binding-protein-dependent transport system permease family
K01997
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000002019
261.0
View
HKD2_k127_4642278_21
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K01356
-
3.4.21.88
0.00000000000000000000000000000000000000000000000000000000000000000000000002471
257.0
View
HKD2_k127_4642278_22
PFAM ABC transporter related
K01996
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000001758
256.0
View
HKD2_k127_4642278_23
Belongs to the peptidase S11 family
K07258
-
3.4.16.4
0.0000000000000000000000000000000000000000000000000000000000000000001983
246.0
View
HKD2_k127_4642278_24
Belongs to the binding-protein-dependent transport system permease family
K01998
-
-
0.0000000000000000000000000000000000000000000000000000000000000000005349
241.0
View
HKD2_k127_4642278_25
PFAM PHP domain
K07053
-
3.1.3.97
0.00000000000000000000000000000000000000000000000000000000000001562
228.0
View
HKD2_k127_4642278_26
VanW like protein
-
-
-
0.000000000000000000000000000000000000000000000000000000000002234
232.0
View
HKD2_k127_4642278_27
Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K00180
-
1.2.7.8
0.000000000000000000000000000000000000000000000000000000001956
209.0
View
HKD2_k127_4642278_28
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K00759
-
2.4.2.7
0.00000000000000000000000000000000000000000000000000000001663
203.0
View
HKD2_k127_4642278_29
Belongs to the purine pyrimidine phosphoribosyltransferase family
K00760
GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659
2.4.2.8
0.00000000000000000000000000000000000000000000000000000007244
201.0
View
HKD2_k127_4642278_3
Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
K01912
-
6.2.1.30
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396
557.0
View
HKD2_k127_4642278_30
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K07738
-
-
0.000000000000000000000000000000000000000000000000000000207
197.0
View
HKD2_k127_4642278_31
This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
K01520
-
3.6.1.23
0.0000000000000000000000000000000000000000000000000001919
199.0
View
HKD2_k127_4642278_32
The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
K02437
-
-
0.00000000000000000000000000000000000000000000001822
175.0
View
HKD2_k127_4642278_33
NLP P60 protein
K21471
-
-
0.000000000000000000000000000000000000000000001011
179.0
View
HKD2_k127_4642278_34
bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
-
-
-
0.00000000000000000000000000000000000000000002328
169.0
View
HKD2_k127_4642278_35
Mechanosensitive ion channel
-
-
-
0.0000000000000000000000000000000000000001691
160.0
View
HKD2_k127_4642278_36
Psort location Cytoplasmic, score
K00760
-
2.4.2.8
0.00000000000000000000000000000000000004
147.0
View
HKD2_k127_4642278_37
PFAM amino acid-binding ACT domain protein
-
-
-
0.000000000000000000000000000000000002031
142.0
View
HKD2_k127_4642278_38
Stage V sporulation protein S (SpoVS)
K06416
-
-
0.000000000000000000000000000000000003542
142.0
View
HKD2_k127_4642278_39
PFAM Biotin lipoate A B protein ligase
K03800
-
6.3.1.20
0.000000000000000000000000000000000005051
151.0
View
HKD2_k127_4642278_4
Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
K01912
-
6.2.1.30
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629
556.0
View
HKD2_k127_4642278_40
4Fe-4S single cluster domain
K04069
-
1.97.1.4
0.00000000000000000000000000000000002163
148.0
View
HKD2_k127_4642278_41
PFAM amino acid-binding ACT domain protein
-
-
-
0.000000000000000000000000000000501
138.0
View
HKD2_k127_4642278_42
Forkhead associated domain
-
-
-
0.000000000000000000000000001837
119.0
View
HKD2_k127_4642278_43
peptidoglycan binding
K03642
-
-
0.000000000000000000002364
105.0
View
HKD2_k127_4642278_44
Hydrolase, NUDIX family
-
-
-
0.000000000000007316
82.0
View
HKD2_k127_4642278_45
-
-
-
-
0.000000000001218
74.0
View
HKD2_k127_4642278_46
Prepilin-type cleavage methylation N-terminal domain protein
K02456
-
-
0.00000003705
60.0
View
HKD2_k127_4642278_47
membrane
K00389
-
-
0.0000001575
62.0
View
HKD2_k127_4642278_48
Ami_3
K01448
GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464
3.5.1.28
0.000009408
54.0
View
HKD2_k127_4642278_5
Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K06168
-
2.8.4.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863
505.0
View
HKD2_k127_4642278_6
permease
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098
495.0
View
HKD2_k127_4642278_7
GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K03665
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357
482.0
View
HKD2_k127_4642278_8
PFAM Aminotransferase class I and II
K10206
-
2.6.1.83
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358
469.0
View
HKD2_k127_4642278_9
permease
K06901
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063
445.0
View
HKD2_k127_4656007_0
Synthesizes selenophosphate from selenide and ATP
K01008
-
2.7.9.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495
297.0
View
HKD2_k127_4656007_1
PFAM EAL domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000007379
278.0
View
HKD2_k127_4656007_2
Belongs to the glycosyl hydrolase 5 (cellulase A) family
K01190
-
3.2.1.23
0.00000000000000000000000000000000000000000000001109
194.0
View
HKD2_k127_4656007_3
peptidyl-tyrosine sulfation
-
-
-
0.000000007086
66.0
View
HKD2_k127_466183_0
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K01895
-
6.2.1.1
1.019e-292
916.0
View
HKD2_k127_466183_1
damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
K03702
GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136
-
5.564e-270
848.0
View
HKD2_k127_466183_10
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides
K02003
-
-
0.0000000000000000000000000000000000000000000000000000000000001728
238.0
View
HKD2_k127_466183_11
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
K00990
-
2.7.7.59
0.000000000000000000000000000000000000000000000000000000000009204
231.0
View
HKD2_k127_466183_12
Glycosyl transferase 4-like domain
-
-
-
0.00000000000000000000000000000000000000000000000000000003239
212.0
View
HKD2_k127_466183_13
TIGRFAM cell envelope-related function transcriptional attenuator
-
-
-
0.00000000000000000000000000000000000000001083
168.0
View
HKD2_k127_466183_14
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K00859
GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576
2.7.1.24
0.0000000000000000000000000000000000001351
150.0
View
HKD2_k127_466183_15
PFAM Lytic transglycosylase catalytic
K08309
-
-
0.000000000000000000000000000001319
129.0
View
HKD2_k127_466183_16
ATP cob(I)alamin adenosyltransferase
K00798
-
2.5.1.17
0.00000000000000000000000001588
119.0
View
HKD2_k127_466183_17
-
-
-
-
0.000000001158
68.0
View
HKD2_k127_466183_18
Conserved repeat domain
-
-
-
0.000005545
57.0
View
HKD2_k127_466183_2
Glycosyltransferase Family 4
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601
466.0
View
HKD2_k127_466183_3
Ribosomal protein S1
K02945
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482
394.0
View
HKD2_k127_466183_4
NmrA-like family
K01709,K01710,K01784
-
4.2.1.45,4.2.1.46,5.1.3.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525
383.0
View
HKD2_k127_466183_5
Glycosyltransferase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215
306.0
View
HKD2_k127_466183_6
Sugar transferases involved in lipopolysaccharide synthesis
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000005259
287.0
View
HKD2_k127_466183_7
PFAM asparagine synthase
K06864
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000009591
293.0
View
HKD2_k127_466183_8
ABC1 family
K03688
-
-
0.000000000000000000000000000000000000000000000000000000000000000002025
247.0
View
HKD2_k127_466183_9
MacB-like periplasmic core domain
K02004
-
-
0.00000000000000000000000000000000000000000000000000000000000001738
231.0
View
HKD2_k127_4698843_0
potassium uptake protein TrkH
K03498
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017
532.0
View
HKD2_k127_4698843_1
TrkA-N domain
K03499
-
-
0.00000000000000000000000000000000000000000000000000000000000000004471
230.0
View
HKD2_k127_4698843_2
TrkA-N domain
K03499
-
-
0.000000000000000000000000000000000000000000000000003345
190.0
View
HKD2_k127_4698843_3
domain, Protein
-
-
-
0.00000000000000000000000000000003421
145.0
View
HKD2_k127_4698843_4
TIGRFAM diguanylate cyclase (GGDEF) domain
-
-
-
0.0000000000000000000000009845
118.0
View
HKD2_k127_4698843_5
-
-
-
-
0.000000000000000000001062
111.0
View
HKD2_k127_4698843_6
DNA topoisomerase type I activity
K03169
-
5.99.1.2
0.00000000000000005249
82.0
View
HKD2_k127_4698843_7
Protein of unknown function (DUF1461)
-
-
-
0.0000000000001834
84.0
View
HKD2_k127_4698843_8
PFAM Peptidase family M28
-
-
-
0.0000000000002859
83.0
View
HKD2_k127_4698843_9
Peptidase family M23
-
-
-
0.0002533
49.0
View
HKD2_k127_5118083_0
Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
K01711
-
4.2.1.47
0.0000000000000000000000000000000000000000000000000000000000000000000000000006849
262.0
View
HKD2_k127_5118083_1
Glycosyltransferase like family 2
-
-
-
0.0000000000000000000000000000000000000000000006126
177.0
View
HKD2_k127_5138491_0
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
K03701
-
-
0.0
1247.0
View
HKD2_k127_5138491_1
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
K03703
-
-
3.655e-212
678.0
View
HKD2_k127_5138491_2
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
K00134
-
1.2.1.12
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267
504.0
View
HKD2_k127_5138491_3
TIGRFAM Ammonium transporter
K03320
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475
478.0
View
HKD2_k127_5138491_4
May be required for sporulation
K09762
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171
370.0
View
HKD2_k127_5138491_5
Displays ATPase and GTPase activities
K06958
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354
316.0
View
HKD2_k127_5138491_6
Required for morphogenesis under gluconeogenic growth conditions
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000001178
245.0
View
HKD2_k127_5138491_7
Belongs to the phosphoglycerate kinase family
K00927
GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065
2.7.2.3
0.00000000000000000000000000000000000000000000000000000000003151
208.0
View
HKD2_k127_5138491_8
Nitrogen regulatory protein P-II
-
-
-
0.000000000000000000000000000000000000000001434
161.0
View
HKD2_k127_5138491_9
Mycobacterial 4 TMS phage holin, superfamily IV
K08972
-
-
0.000000000000000001218
92.0
View
HKD2_k127_5146081_0
Acetyl-CoA carboxylase, biotin carboxyl carrier protein
K01571
-
4.1.1.3
3.384e-267
837.0
View
HKD2_k127_5146081_1
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
K01937
-
6.3.4.2
2.849e-251
784.0
View
HKD2_k127_5146081_10
arylsulfatase activity
-
-
-
0.00000000000000000000000000000000000000000000002716
195.0
View
HKD2_k127_5146081_11
TIGRFAM peptidase T-like protein
K01258
-
3.4.11.4
0.00000000000000000000000000000000000000000001089
176.0
View
HKD2_k127_5146081_12
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K00858
GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576
2.7.1.23
0.000000000000000000000000000000000000000001059
169.0
View
HKD2_k127_5146081_13
Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K03625
-
-
0.00000000000000000000000000000000005262
141.0
View
HKD2_k127_5146081_14
First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
-
-
-
0.0000000000000000000000000001054
131.0
View
HKD2_k127_5146081_15
Asp23 family, cell envelope-related function
-
-
-
0.00000000000000000005351
94.0
View
HKD2_k127_5146081_16
Copper transport outer membrane protein, MctB
-
-
-
0.000000002487
68.0
View
HKD2_k127_5146081_17
Exonuclease VII small subunit
-
-
-
0.0003381
48.0
View
HKD2_k127_5146081_2
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K01662
-
2.2.1.7
8.733e-227
721.0
View
HKD2_k127_5146081_3
TIGRFAM acetyl-CoA carboxylase, biotin carboxylase
K01961
-
6.3.4.14,6.4.1.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057
599.0
View
HKD2_k127_5146081_4
Thiamine pyrophosphokinase C terminal
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371
431.0
View
HKD2_k127_5146081_5
May be involved in recombinational repair of damaged DNA
K03631,K13582
GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0030312,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238
411.0
View
HKD2_k127_5146081_6
integral membrane protein MviN
K03980
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011
372.0
View
HKD2_k127_5146081_7
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K02356
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000001115
260.0
View
HKD2_k127_5146081_8
Ribosomal RNA large subunit methyltransferase J
K06442
-
2.1.1.226,2.1.1.227
0.0000000000000000000000000000000000000000000000000000000000000000000000000002466
265.0
View
HKD2_k127_5146081_9
PFAM Glycosyl transferase family 2
-
-
-
0.00000000000000000000000000000000000000000000000000000000000997
233.0
View
HKD2_k127_5250485_0
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
K04487
-
2.8.1.7
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919
419.0
View
HKD2_k127_5250485_1
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
K00566
-
2.8.1.13
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141
304.0
View
HKD2_k127_5250485_10
Transcriptional regulator, BadM Rrf2 family
-
-
-
0.00000002837
57.0
View
HKD2_k127_5250485_2
TIGRFAM histidinol phosphate phosphatase HisJ
K04486
-
3.1.3.15
0.0000000000000000000000000000000000000000000000000000000000000000000002035
261.0
View
HKD2_k127_5250485_3
HD domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000774
225.0
View
HKD2_k127_5250485_4
NIF3 (NGG1p interacting factor 3)
-
-
-
0.0000000000000000000000000000000000000000000000000000009253
211.0
View
HKD2_k127_5250485_5
NifU-like N terminal domain
K04488
-
-
0.000000000000000000000000000000000000000000000000001173
188.0
View
HKD2_k127_5250485_6
Helix-turn-helix diphteria tox regulatory element
K03709
-
-
0.0000000000000000000000000000000000000006041
157.0
View
HKD2_k127_5250485_7
PFAM ribonuclease H
K03469,K06864
-
3.1.26.4
0.00000000000000000000000000000000006432
141.0
View
HKD2_k127_5250485_8
6-pyruvoyl tetrahydropterin synthase
K01737
-
4.1.2.50,4.2.3.12
0.000000000000000000000000000000001503
132.0
View
HKD2_k127_5250485_9
zinc ribbon domain
K07164
-
-
0.0000000000000000000000002232
114.0
View
HKD2_k127_5513086_0
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K01866
-
6.1.1.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229
522.0
View
HKD2_k127_5513086_1
Penicillin-binding Protein
K05366
-
2.4.1.129,3.4.16.4
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215
348.0
View
HKD2_k127_5513086_2
-
-
-
-
0.00000001644
55.0
View
HKD2_k127_5591071_0
biogenesis protein CcmF
K02198
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386
480.0
View
HKD2_k127_5591071_1
Catalyzes the oxidation of L-aspartate to iminoaspartate
K00278
-
1.4.3.16
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086
469.0
View
HKD2_k127_5591071_10
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
K03525
-
2.7.1.33
0.00000000000000000000000000000000000000000000000000000000000000000000000000004585
266.0
View
HKD2_k127_5591071_11
heme exporter protein CcmB
K02194
-
-
0.00000000000000000000000000000000000000000000000000000000000001346
223.0
View
HKD2_k127_5591071_12
histidine kinase DNA gyrase B
-
-
-
0.00000000000000000000000000000000000000000000000000000000006498
222.0
View
HKD2_k127_5591071_13
Cytochrome c assembly protein
K02195
-
-
0.00000000000000000000000000000000000000000000000000000000007181
212.0
View
HKD2_k127_5591071_14
Belongs to the NadC ModD family
K00767
-
2.4.2.19
0.000000000000000000000000000000000000000000000000001177
195.0
View
HKD2_k127_5591071_15
Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
K03524
-
6.3.4.15
0.000000000000000000000000000000000000000000000000005685
197.0
View
HKD2_k127_5591071_16
oligosaccharyl transferase activity
-
-
-
0.0000000000000000000000000000000000000000000009487
186.0
View
HKD2_k127_5591071_17
PFAM helix-turn-helix domain protein
-
-
-
0.0000000000000000000000000000000000001234
149.0
View
HKD2_k127_5591071_18
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K00950,K13940
-
2.7.6.3,4.1.2.25
0.00000000000000000000000000000003133
136.0
View
HKD2_k127_5591071_19
SNARE associated Golgi protein
K03975
-
-
0.0000000000000000000000057
114.0
View
HKD2_k127_5591071_2
quinolinate synthetase A activity
K03517
GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605
2.5.1.72
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413
339.0
View
HKD2_k127_5591071_20
BioY family
K03523
-
-
0.0000000000000000001144
102.0
View
HKD2_k127_5591071_21
Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
K02197
-
-
0.000000002517
66.0
View
HKD2_k127_5591071_3
Transcriptional regulatory protein, C terminal
K07776
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422
314.0
View
HKD2_k127_5591071_4
dihydropteroate synthase
K00796
-
2.5.1.15
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559
309.0
View
HKD2_k127_5591071_5
PFAM ABC transporter
K01990,K02193,K09697
-
3.6.3.41,3.6.3.7
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106
306.0
View
HKD2_k127_5591071_6
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
K00606
-
2.1.2.11
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903
310.0
View
HKD2_k127_5591071_7
oxidoreductase activity
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001917
303.0
View
HKD2_k127_5591071_8
GTP cyclohydrolase
K01495
-
3.5.4.16
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001369
280.0
View
HKD2_k127_5591071_9
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K01918
GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605
6.3.2.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000001311
284.0
View
HKD2_k127_5598455_0
Cell shape determining protein, MreB Mrl family
K03569
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326
480.0
View
HKD2_k127_5598455_1
Penicillin-binding protein 2
K05515
-
3.4.16.4
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779
482.0
View
HKD2_k127_5598455_10
Part of a membrane complex involved in electron transport
K03612
-
-
0.00000000000000001452
90.0
View
HKD2_k127_5598455_11
shape-determining protein MreD
K03571
-
-
0.0000000000002384
78.0
View
HKD2_k127_5598455_12
Heptaprenyl diphosphate synthase component I
K00805
-
2.5.1.30
0.0000000001068
71.0
View
HKD2_k127_5598455_13
NusG domain II
-
-
-
0.00000004942
59.0
View
HKD2_k127_5598455_14
protein domain associated with
-
-
-
0.00001508
53.0
View
HKD2_k127_5598455_2
Belongs to the SEDS family
K05837
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858
321.0
View
HKD2_k127_5598455_3
Part of a membrane complex involved in electron transport
K03614
-
-
0.00000000000000000000000000000000000000000000000000000000000000000002549
252.0
View
HKD2_k127_5598455_4
TIGRFAM electron transport complex, RnfABCDGE type, B subunit
K03616
-
-
0.000000000000000000000000000000000000000000000000000000000000000001594
239.0
View
HKD2_k127_5598455_5
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily
K03615
-
-
0.0000000000000000000000000000000000000000000000000000000000000002379
226.0
View
HKD2_k127_5598455_6
Involved in formation and maintenance of cell shape
K03570
-
-
0.00000000000000000000000000000000000000000000000000000005816
206.0
View
HKD2_k127_5598455_7
Part of a membrane complex involved in electron transport
K03617
-
-
0.000000000000000000000000000000000000000000000000003073
189.0
View
HKD2_k127_5598455_8
electron transport chain
K02560,K03613,K10773
GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944
2.3.1.243,4.2.99.18
0.000000000000000000000000000000000000000000000000004169
188.0
View
HKD2_k127_5598455_9
Belongs to the UPF0758 family
K03630
-
-
0.000000000000000000000000000000000000000000000000006989
188.0
View
HKD2_k127_5627941_0
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K03106
-
3.6.5.4
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644
305.0
View
HKD2_k127_5627941_1
Belongs to the RNA methyltransferase TrmD family
K00554
-
2.1.1.228
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004481
287.0
View
HKD2_k127_5627941_10
Belongs to the UPF0109 family
K06960
-
-
0.000000000000000017
84.0
View
HKD2_k127_5627941_2
Magnesium chelatase, subunit ChlI C-terminal
K07391
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008218
286.0
View
HKD2_k127_5627941_3
Belongs to the peptidase S26 family
K03100
-
3.4.21.89
0.000000000000000000000000000000000000000000000004565
178.0
View
HKD2_k127_5627941_4
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
K02884
-
-
0.0000000000000000000000000000000000000000000002692
169.0
View
HKD2_k127_5627941_5
Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K03470
GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576
3.1.26.4
0.000000000000000000000000000000000000000002595
172.0
View
HKD2_k127_5627941_6
Belongs to the peptidase S26 family
K03100
-
3.4.21.89
0.00000000000000000000000000000000000000004849
160.0
View
HKD2_k127_5627941_7
Belongs to the UPF0102 family
K07460
-
-
0.0000000000000000000000000001717
118.0
View
HKD2_k127_5627941_8
Belongs to the bacterial ribosomal protein bS16 family
K02959
-
-
0.00000000000000000000000008212
113.0
View
HKD2_k127_5627941_9
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K02860
-
-
0.00000000000000000008105
95.0
View
HKD2_k127_5678909_0
type II secretion system protein E
K02652
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204
517.0
View
HKD2_k127_5678909_1
Phosphotransfer between the C1 and C5 carbon atoms of pentose
K01839
-
5.4.2.7
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561
465.0
View
HKD2_k127_5678909_2
Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
K00756
GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464
2.4.2.2
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272
470.0
View
HKD2_k127_5678909_3
tRNA nucleotidyltransferase poly(A) polymerase
K00974
-
2.7.7.72
0.00000000000000000000000000000000000006006
149.0
View
HKD2_k127_5695468_0
Cache domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000003344
225.0
View
HKD2_k127_5695468_1
PFAM MCP methyltransferase CheR-type
K00575
-
2.1.1.80
0.0000000000000000000000000000000000000000000000000000002709
205.0
View
HKD2_k127_5695468_2
Chemotaxis signal transduction protein
K03408
-
-
0.000000000000000000000000009131
119.0
View
HKD2_k127_5695468_3
Putative peptidoglycan binding domain
-
-
-
0.000000000000000000000001065
121.0
View
HKD2_k127_5695468_4
Doubled CXXCH motif (Paired_CXXCH_1)
-
-
-
0.000000000000001204
92.0
View
HKD2_k127_5695468_5
Fibronectin type III domain protein
-
-
-
0.0000001263
66.0
View
HKD2_k127_5695468_6
gluconolactonase activity
K14274
-
-
0.0000005246
63.0
View
HKD2_k127_5695468_7
Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
-
-
-
0.000001144
63.0
View
HKD2_k127_5757069_0
Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603
585.0
View
HKD2_k127_5757069_1
UDP-N-acetylglucosamine 2-epimerase
K08068,K18429
-
3.2.1.183,3.2.1.184
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634
547.0
View
HKD2_k127_5757069_10
Methionine biosynthesis protein MetW
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000103
270.0
View
HKD2_k127_5757069_11
Glycosyl transferase family 2
K00721
-
2.4.1.83
0.000000000000000000000000000000000000000000000000000000000000000002101
239.0
View
HKD2_k127_5757069_13
PFAM Methyltransferase domain
-
-
-
0.000000000000000000000000000000000000000000000000000000001617
218.0
View
HKD2_k127_5757069_14
polysaccharide biosynthetic process
-
-
-
0.000000000000000000000000000001953
139.0
View
HKD2_k127_5757069_15
O-acyltransferase activity
-
-
-
0.0000000000000000000000003335
113.0
View
HKD2_k127_5757069_16
-
-
-
-
0.000000000000006825
89.0
View
HKD2_k127_5757069_17
GtrA-like protein
-
-
-
0.000000000009691
76.0
View
HKD2_k127_5757069_2
Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
K02377
-
1.1.1.271
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668
461.0
View
HKD2_k127_5757069_3
Belongs to the mannose-6-phosphate isomerase type 2 family
K16011
-
2.7.7.13,5.3.1.8
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573
386.0
View
HKD2_k127_5757069_4
Oxidoreductase family, NAD-binding Rossmann fold
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867
361.0
View
HKD2_k127_5757069_5
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K00058
-
1.1.1.399,1.1.1.95
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223
350.0
View
HKD2_k127_5757069_6
Belongs to the TPP enzyme family
K01652
-
2.2.1.6
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084
353.0
View
HKD2_k127_5757069_7
NeuB family
K01654
-
2.5.1.56
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244
341.0
View
HKD2_k127_5757069_8
Methyltransferase domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001418
286.0
View
HKD2_k127_5757069_9
Cytidylyltransferase
K00983,K18431
-
2.7.7.43,2.7.7.82
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005286
282.0
View
HKD2_k127_5929732_0
Alpha-amylase domain
K01187
-
3.2.1.20
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269
497.0
View
HKD2_k127_5929732_1
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
K07652
-
2.7.13.3
0.000000000000000000000000000000000000000000000000000000000000000000001309
258.0
View
HKD2_k127_5929732_10
denitrification pathway
-
-
-
0.00000000000001135
85.0
View
HKD2_k127_5929732_11
-
-
-
-
0.000000000002764
76.0
View
HKD2_k127_5929732_2
4Fe-4S dicluster domain
K00184
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000102
254.0
View
HKD2_k127_5929732_3
Transcriptional regulatory protein, C terminal
K02483,K07658
-
-
0.00000000000000000000000000000000000000000000000000000000000003224
223.0
View
HKD2_k127_5929732_4
Polysulphide reductase, NrfD
K00185
-
-
0.0000000000000000000000000000000000000000000001649
184.0
View
HKD2_k127_5929732_5
PFAM Glycosyl transferase family 2
-
-
-
0.000000000000000000000000000000000000000001973
177.0
View
HKD2_k127_5929732_6
NapC/NirT cytochrome c family, N-terminal region
-
-
-
0.00000000000000000000000000000000003751
147.0
View
HKD2_k127_5929732_7
NapC/NirT cytochrome c family, N-terminal region
-
-
-
0.000000000000000000000000000000655
132.0
View
HKD2_k127_5929732_8
denitrification pathway
-
-
-
0.000000000000000000000001569
116.0
View
HKD2_k127_5929732_9
Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
K11991
-
3.5.4.33
0.000000000000000005537
86.0
View
HKD2_k127_5984225_0
Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K00013
-
1.1.1.23
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428
469.0
View
HKD2_k127_5984225_1
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K00817
-
2.6.1.9
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895
415.0
View
HKD2_k127_5984225_2
DNA polymerase III alpha subunit
K02337
-
2.7.7.7
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185
329.0
View
HKD2_k127_5984225_3
Imidazoleglycerol-phosphate dehydratase
K01693
-
4.2.1.19
0.000000000000000000000000000000000000000000000000000000000000000000000000001812
258.0
View
HKD2_k127_6124481_0
Glutamine synthetase, catalytic domain
K01915
-
6.3.1.2
1.373e-194
617.0
View
HKD2_k127_6124481_1
Conserved region in glutamate synthase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755
562.0
View
HKD2_k127_6124481_2
COGs COG0491 Zn-dependent hydrolase including glyoxylase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000002129
240.0
View
HKD2_k127_6124481_3
Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
-
-
-
0.0000000000000000000001722
106.0
View
HKD2_k127_6223509_0
pilus assembly protein ATPase CpaF
K02283
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689
544.0
View
HKD2_k127_6223509_1
Type ii secretion system
K12510
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000001968
270.0
View
HKD2_k127_6223509_2
Type II secretion system
K12511
-
-
0.000000000000000000000000000000000000000000000000000000001018
212.0
View
HKD2_k127_6223509_3
Evidence 2b Function of strongly homologous gene
K02282
-
-
0.0000000000000000000000000000000000000000000000000000001448
211.0
View
HKD2_k127_6223509_4
Putative Flp pilus-assembly TadE/G-like
-
-
-
0.0000000000000000000000003572
118.0
View
HKD2_k127_6223509_5
Flp pilus assembly protein RcpC/CpaB
K02279
-
-
0.00000000000000002548
91.0
View
HKD2_k127_6223509_6
GTP cyclohydrolase
K01495
-
3.5.4.16
0.00000000000004698
74.0
View
HKD2_k127_6223509_7
TadE-like protein
-
-
-
0.0000000000000771
76.0
View
HKD2_k127_6300958_0
Participates in initiation and elongation during chromosome replication
K02314
GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576
3.6.4.12
0.00000000000000000000000000000000000000000000000000000000004036
217.0
View
HKD2_k127_6300958_1
Binds to the 23S rRNA
K02939
-
-
0.0000000000000000000000000000000000000000000007917
174.0
View
HKD2_k127_6300958_2
Single-stranded DNA-binding protein
K03111
-
-
0.00000000000000000000000000000000007753
138.0
View
HKD2_k127_6300958_3
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
K02963
-
-
0.0000000000000000000000000000000003542
134.0
View
HKD2_k127_6300958_4
Binds together with S18 to 16S ribosomal RNA
K02990
-
-
0.000000000000000000000000000003831
127.0
View
HKD2_k127_6391399_0
ABC transporter, transmembrane region
K06147
-
-
1.047e-263
835.0
View
HKD2_k127_6391399_1
ABC transporter, transmembrane region
K06147
-
-
3.489e-236
746.0
View
HKD2_k127_6391399_10
Rhodanese Homology Domain
K21028
-
2.8.1.11
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099
368.0
View
HKD2_k127_6391399_11
Alcohol dehydrogenase GroES domain protein
K00008
-
1.1.1.14
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553
348.0
View
HKD2_k127_6391399_12
COGs COG1125 ABC-type proline glycine betaine transport systems ATPase components
K05847
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178
329.0
View
HKD2_k127_6391399_13
glycine, betaine
K05845
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274
317.0
View
HKD2_k127_6391399_14
Protein of unknown function (DUF3365)
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752
308.0
View
HKD2_k127_6391399_15
May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K06187
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002913
289.0
View
HKD2_k127_6391399_16
Enoyl-(Acyl carrier protein) reductase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000155
289.0
View
HKD2_k127_6391399_17
HD domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000001938
265.0
View
HKD2_k127_6391399_18
UbiA prenyltransferase family
K02548
-
2.5.1.74
0.0000000000000000000000000000000000000000000000000000000000000002154
231.0
View
HKD2_k127_6391399_19
Binding-protein-dependent transport system inner membrane component
K05846
GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337
-
0.000000000000000000000000000000000000000000000000000000005234
213.0
View
HKD2_k127_6391399_2
Belongs to the aspartokinase family
K00928
-
2.7.2.4
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471
493.0
View
HKD2_k127_6391399_20
PFAM thioesterase superfamily
-
-
-
0.0000000000000000000000000000000000000000000000000000006969
198.0
View
HKD2_k127_6391399_21
response regulator, receiver
-
-
-
0.000000000000000000000000000000000000000000000000000003196
203.0
View
HKD2_k127_6391399_22
Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K00172
-
1.2.7.1
0.00000000000000000000000000000000000000000000000000003458
193.0
View
HKD2_k127_6391399_23
PBP superfamily domain
K02040
-
-
0.00000000000000000000000000000000000000000000000005587
190.0
View
HKD2_k127_6391399_24
Signal transduction histidine kinase
-
-
-
0.000000000000000000000000000000000000000000000005466
190.0
View
HKD2_k127_6391399_25
PFAM Binding-protein-dependent transport system inner membrane component
K05846
GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337
-
0.0000000000000000000000000000000000000000000447
180.0
View
HKD2_k127_6391399_26
Transmembrane secretion effector
-
-
-
0.000000000000000000000000000000000000000001526
171.0
View
HKD2_k127_6391399_27
DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
K05982
-
3.1.21.7
0.000000000000000000000000000000001129
147.0
View
HKD2_k127_6391399_28
4Fe-4S dicluster domain
K00171
-
1.2.7.1
0.000000000000000000000000000000001288
134.0
View
HKD2_k127_6391399_3
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K02343
-
2.7.7.7
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263
473.0
View
HKD2_k127_6391399_30
Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
K09747
-
-
0.00000000000000000000000001879
113.0
View
HKD2_k127_6391399_31
DNA-binding transcription factor activity
-
-
-
0.00000000000000000000000002657
115.0
View
HKD2_k127_6391399_32
PFAM Uncharacterised BCR, COG1649
-
-
-
0.0000000000000000000000004631
123.0
View
HKD2_k127_6391399_33
transcriptional regulator
K10914
GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141
-
0.0000000000000000003849
93.0
View
HKD2_k127_6391399_4
Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K00133
-
1.2.1.11
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353
469.0
View
HKD2_k127_6391399_5
PFAM Pyruvate flavodoxin ferredoxin oxidoreductase
K00169
-
1.2.7.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382
445.0
View
HKD2_k127_6391399_6
Immune inhibitor A peptidase M6
K09607
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751
426.0
View
HKD2_k127_6391399_7
tRNA (guanine-N7-)-methyltransferase activity
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276
432.0
View
HKD2_k127_6391399_8
tRNA-splicing ligase RtcB
K14415
-
6.5.1.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152
417.0
View
HKD2_k127_6391399_9
PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
K00170
-
1.2.7.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752
413.0
View
HKD2_k127_649922_0
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K02355
-
-
1.575e-301
940.0
View
HKD2_k127_649922_1
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K02358
-
-
0.0000000000000000000000000000000000000000116
154.0
View
HKD2_k127_649922_2
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
K02992
GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.00000000000005062
71.0
View
HKD2_k127_6514016_0
beta-propeller repeat
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685
330.0
View
HKD2_k127_6514016_1
4Fe-4S ferredoxin iron-sulfur binding domain protein
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000006165
253.0
View
HKD2_k127_6514016_2
N-acetylglucosaminylinositol deacetylase activity
-
-
-
0.0000000000000000000000000001249
125.0
View
HKD2_k127_6538976_0
DNA helicase
K03657
-
3.6.4.12
1.541e-236
753.0
View
HKD2_k127_6538976_1
DHHA2
K15986
-
3.6.1.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474
410.0
View
HKD2_k127_6538976_10
Single Cache-like
K07636
-
2.7.13.3
0.000000000000000000000000000000000000000000000000000000000001352
231.0
View
HKD2_k127_6538976_11
phosphatidate phosphatase activity
K03975,K19302
-
3.6.1.27
0.000000000000000000000000000000000000000000000000000000000008503
228.0
View
HKD2_k127_6538976_12
Chorismate mutase type II
-
-
-
0.0000000000000000000005397
98.0
View
HKD2_k127_6538976_2
nitronate monooxygenase activity
K00088,K00459
-
1.1.1.205,1.13.12.16
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033
331.0
View
HKD2_k127_6538976_3
DAHP synthetase I family
K03856
-
2.5.1.54
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281
312.0
View
HKD2_k127_6538976_4
ATPases associated with a variety of cellular activities
K02036
-
3.6.3.27
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107
309.0
View
HKD2_k127_6538976_5
Phosphate transport system permease protein PstA
K02038
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000002067
267.0
View
HKD2_k127_6538976_6
GlcNAc-PI de-N-acetylase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000001387
259.0
View
HKD2_k127_6538976_7
Response regulator receiver
K07776
GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141
-
0.00000000000000000000000000000000000000000000000000000000000000003834
235.0
View
HKD2_k127_6538976_8
probably responsible for the translocation of the substrate across the membrane
K02037
-
-
0.0000000000000000000000000000000000000000000000000000000000000001733
232.0
View
HKD2_k127_6538976_9
TIGRFAM phosphate binding protein
K02040
-
-
0.00000000000000000000000000000000000000000000000000000000000003186
228.0
View
HKD2_k127_6568489_0
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K03628
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487
584.0
View
HKD2_k127_6568489_1
Domain of unknown function (DUF4153)
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595
565.0
View
HKD2_k127_6568489_10
2-phosphoglycerate kinase
K05715
-
-
0.0000000000000000000000000000000000000000000000000000000000000000245
241.0
View
HKD2_k127_6568489_11
-
-
-
-
0.0000000000000000000000000000000000000000000000000000000004509
207.0
View
HKD2_k127_6568489_12
Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
K01586
-
4.1.1.20
0.000000000000000000000000000000000000000000000000000000003232
201.0
View
HKD2_k127_6568489_13
Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
K00872
-
2.7.1.39
0.0000000000000000000000000000000000000000000000000000001504
205.0
View
HKD2_k127_6568489_14
signal peptide peptidase SppA, 36K type
K04773
-
-
0.000000000000000000000000000000000000000000000000000001527
204.0
View
HKD2_k127_6568489_15
Allomyces macrogynus ATCC 38327
-
-
-
0.000000000000000000000000000000000000000000000000000007674
198.0
View
HKD2_k127_6568489_16
PFAM Hemerythrin HHE cation binding domain
-
-
-
0.0000000000000000000000000000000000000000000000001183
182.0
View
HKD2_k127_6568489_17
Transcriptional regulator
-
-
-
0.000000000000000000000000000000000000000000002194
168.0
View
HKD2_k127_6568489_18
transferase activity, transferring acyl groups
K03824
GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564
-
0.000000000000000000000000000000000000000000003553
172.0
View
HKD2_k127_6568489_19
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K00616,K08314
-
2.2.1.2
0.0000000000000000000000000000000000000000002707
173.0
View
HKD2_k127_6568489_2
homoserine dehydrogenase
K00003
-
1.1.1.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776
485.0
View
HKD2_k127_6568489_20
InterPro IPR014922
-
-
-
0.0000000000000000000000000000000000000007892
160.0
View
HKD2_k127_6568489_21
Domain of unknown function (DUF4386)
-
-
-
0.000000000000000000000000000000000000001903
157.0
View
HKD2_k127_6568489_22
Domain of unknown function (DU1801)
-
-
-
0.00000000000000000000000000000000000001977
147.0
View
HKD2_k127_6568489_23
Binds the 23S rRNA
K02909
-
-
0.00000000000000000000000000000000001249
146.0
View
HKD2_k127_6568489_24
Helix-turn-helix domain
K07729
-
-
0.0000000000000000000000000000006229
126.0
View
HKD2_k127_6568489_25
Iron-binding zinc finger CDGSH type
-
-
-
0.000000000000000000001119
97.0
View
HKD2_k127_6568489_26
Acetyltransferase (GNAT) domain
-
-
-
0.00000000000000002596
89.0
View
HKD2_k127_6568489_27
-
-
-
-
0.0000000000000001795
86.0
View
HKD2_k127_6568489_28
-
-
-
-
0.00000000000006154
82.0
View
HKD2_k127_6568489_29
TOBE domain
-
-
-
0.0000000000005406
72.0
View
HKD2_k127_6568489_3
transporter
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626
381.0
View
HKD2_k127_6568489_30
-
-
-
-
0.000000006913
64.0
View
HKD2_k127_6568489_31
methyltransferase
-
-
-
0.0000003119
59.0
View
HKD2_k127_6568489_32
-
-
-
-
0.00002396
53.0
View
HKD2_k127_6568489_4
Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP
K05716
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512
359.0
View
HKD2_k127_6568489_5
lactate metabolic process
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672
318.0
View
HKD2_k127_6568489_6
Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
K03465
-
2.1.1.148
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208
310.0
View
HKD2_k127_6568489_7
oxidoreductase activity
K21883
-
1.1.1.401
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796
301.0
View
HKD2_k127_6568489_8
acid phosphatase activity
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947
298.0
View
HKD2_k127_6568489_9
Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K16264
-
-
0.0000000000000000000000000000000000000000000000000000000000000000003139
240.0
View
HKD2_k127_675376_0
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K02335
-
2.7.7.7
1.007e-258
832.0
View
HKD2_k127_675376_1
Glutamine synthetase, beta-grasp domain
K01915
-
6.3.1.2
1.974e-200
634.0
View
HKD2_k127_675376_2
Ribosomal protein S1
K02945
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000004662
250.0
View
HKD2_k127_675376_3
Reversible hydration of carbon dioxide
K01673
-
4.2.1.1
0.000000000000000000000000000000000000000000000000000000000000000005868
236.0
View
HKD2_k127_675376_4
Transcriptional regulatory protein
-
-
-
0.000000000000000000000000000000000000000000000000000000002097
207.0
View
HKD2_k127_675376_5
methyltransferase
K03183
-
2.1.1.163,2.1.1.201
0.0000000000000000000000001273
115.0
View
HKD2_k127_675376_6
PFAM Copper binding proteins, plastocyanin azurin family
-
-
-
0.00000000000000000000006474
115.0
View
HKD2_k127_6769225_0
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K00937
-
2.7.4.1
2.114e-232
739.0
View
HKD2_k127_6769225_1
polyphosphate kinase
K22468
-
2.7.4.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914
408.0
View
HKD2_k127_6769225_2
PFAM Glucose Sorbosone dehydrogenase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625
316.0
View
HKD2_k127_6769225_3
enzyme of poly-gamma-glutamate biosynthesis (Capsule formation)
K07282
-
-
0.00000000000000000000000000000000000000000000000000000003304
215.0
View
HKD2_k127_6769225_4
metal-dependent phosphohydrolase, HD sub domain
K01524
-
3.6.1.11,3.6.1.40
0.00000000000000000000000000000000000000000000000332
185.0
View
HKD2_k127_6769225_5
Protein of unknown function (DUF2769)
-
-
-
0.00000000000000000009861
91.0
View
HKD2_k127_6769225_6
-
-
-
-
0.0000000000000003545
87.0
View
HKD2_k127_6805632_0
Catalyzes the synthesis of GMP from XMP
K01951
GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659
6.3.5.2
2.495e-207
661.0
View
HKD2_k127_6805632_1
IMP dehydrogenase / GMP reductase domain
K00088
-
1.1.1.205
1.598e-202
642.0
View
HKD2_k127_6805632_2
COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
-
-
-
0.00000000000000000000000000000000000000000000000000000000236
204.0
View
HKD2_k127_6805632_3
GTPase that plays an essential role in the late steps of ribosome biogenesis
K03977
-
-
0.00000000000000000000000000000000000000000000003728
178.0
View
HKD2_k127_6824017_0
40-residue YVTN family beta-propeller
-
-
-
0.000000000000000000000000000000000000000004701
178.0
View
HKD2_k127_6824017_1
Belongs to the short-chain dehydrogenases reductases (SDR) family
-
-
-
0.000000000000000000001731
102.0
View
HKD2_k127_6824017_2
depolymerase
K03932
-
-
0.00000000002758
76.0
View
HKD2_k127_70310_0
GTPase that plays an essential role in the late steps of ribosome biogenesis
K03977
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781
574.0
View
HKD2_k127_70310_1
FeS-containing Cyanobacterial-specific oxidoreductase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228
332.0
View
HKD2_k127_70310_2
Glycerol-3-phosphate dehydrogenase
K00057
-
1.1.1.94
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009688
317.0
View
HKD2_k127_70310_3
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K03527
-
1.17.7.4
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003701
292.0
View
HKD2_k127_70310_4
Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K11752
-
1.1.1.193,3.5.4.26
0.00000000000000000000000000000000000000000000000000000000000000000000000006194
264.0
View
HKD2_k127_70310_5
Ribulose-phosphate 3 epimerase family
K01783
GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575
5.1.3.1
0.0000000000000000000000000000000000000000000000000000000000000000002484
246.0
View
HKD2_k127_70310_6
Lumazine binding domain
K00793
-
2.5.1.9
0.000000000000000000000000000000000000000000000000004106
202.0
View
HKD2_k127_70310_7
Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
K08591
-
2.3.1.15
0.0000000000000000000000000000003995
136.0
View
HKD2_k127_7044125_0
Glutaminyl-tRNA synthetase
K01886
-
6.1.1.18
3.575e-266
829.0
View
HKD2_k127_7044125_1
TIGRFAM DNA polymerase III, alpha subunit
K02337,K14162
-
2.7.7.7
7.864e-226
740.0
View
HKD2_k127_7044125_12
Phosphate-starvation-inducible E
-
-
-
0.00000776
55.0
View
HKD2_k127_7044125_2
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K01885
-
6.1.1.17
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203
591.0
View
HKD2_k127_7044125_3
AAA domain (dynein-related subfamily)
K03404,K03405
-
6.6.1.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659
555.0
View
HKD2_k127_7044125_4
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K02346
-
2.7.7.7
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338
381.0
View
HKD2_k127_7044125_5
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K00789
-
2.5.1.6
0.00000000000000000000000000000000000000000000000000000000000000000000000000000003834
276.0
View
HKD2_k127_7044125_6
EXOIII
K02342
-
2.7.7.7
0.0000000000000000000000000000000000000000000000000000000000000000227
244.0
View
HKD2_k127_7044125_7
Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
K01151
GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360
3.1.21.2
0.00000000000000000000000000000000000000000000000000004191
203.0
View
HKD2_k127_7044125_8
calcium- and calmodulin-responsive adenylate cyclase activity
K08372
-
-
0.00000000000000000000000000000000324
143.0
View
HKD2_k127_7044125_9
Subtilase family
K13274,K14645
-
-
0.0000000006633
72.0
View
HKD2_k127_7048122_0
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K02355
-
-
1.029e-298
931.0
View
HKD2_k127_7048122_1
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K02358
GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944
-
0.000000000001682
68.0
View
HKD2_k127_7315761_0
response regulator receiver
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135
343.0
View
HKD2_k127_7315761_1
Responsible for synthesis of pseudouridine from uracil
K06180
-
5.4.99.23
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009818
353.0
View
HKD2_k127_7315761_2
ATPase histidine kinase DNA gyrase B HSP90 domain protein
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354
321.0
View
HKD2_k127_7315761_3
Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K13292
-
-
0.0000000000000000000000000000000000008182
152.0
View
HKD2_k127_7315761_4
This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K03101
-
3.4.23.36
0.0000000000000000000000001391
111.0
View
HKD2_k127_757011_0
Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K13038
-
4.1.1.36,6.3.2.5
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568
384.0
View
HKD2_k127_757011_1
TIGRFAM 2-oxoacid acceptor oxidoreductase, alpha subunit
K00174
-
1.2.7.11,1.2.7.3
0.000000000000000000000000000000000000000000000000000002508
214.0
View
HKD2_k127_763793_0
Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K04066
GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976
582.0
View
HKD2_k127_763793_1
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K00789
-
2.5.1.6
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838
418.0
View
HKD2_k127_763793_2
fructose-1,6-bisphosphatase
K02446
-
3.1.3.11
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414
357.0
View
HKD2_k127_763793_3
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family
K03500
-
2.1.1.176
0.00000000000000000000000000000000000000000000000000000000000000000000000001327
273.0
View
HKD2_k127_763793_4
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K00604
-
2.1.2.9
0.00000000000000000000000000000000000000000000000000000000000000000000002588
254.0
View
HKD2_k127_763793_5
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
K01462
-
3.5.1.88
0.0000000000000000000000000000000001761
137.0
View
HKD2_k127_763793_6
Putative regulatory protein
-
-
-
0.000000000001609
71.0
View
HKD2_k127_763793_7
Protein tyrosine kinase
-
-
-
0.00000000001645
76.0
View
HKD2_k127_764143_0
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K01972
-
6.5.1.2
2.485e-221
699.0
View
HKD2_k127_764143_1
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
K02433
-
6.3.5.6,6.3.5.7
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034
555.0
View
HKD2_k127_764143_10
cyclic-guanylate-specific phosphodiesterase activity
-
-
-
0.000001711
61.0
View
HKD2_k127_764143_11
Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K07027
-
-
0.000002988
59.0
View
HKD2_k127_764143_12
Cobyrinic acid ac-diamide synthase
-
-
-
0.0000159
57.0
View
HKD2_k127_764143_2
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides
K02003
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000006441
245.0
View
HKD2_k127_764143_3
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides
K02003
-
-
0.000000000000000000000000000000000000000000000000000000000000000000001536
248.0
View
HKD2_k127_764143_4
ABC-type transport system involved in lipoprotein release permease component
K02004
-
-
0.000000000000000000000000000000000000000000000000001108
198.0
View
HKD2_k127_764143_5
ABC-type transport system involved in lipoprotein release permease component
K02004
-
-
0.000000000000000000000000000000000000000000006709
179.0
View
HKD2_k127_764143_6
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K02435
-
6.3.5.6,6.3.5.7
0.000000000000000000003052
98.0
View
HKD2_k127_764143_7
transcriptional regulator
-
-
-
0.00000000000000000004402
98.0
View
HKD2_k127_764143_8
protease
K07052
-
-
0.00000006817
65.0
View
HKD2_k127_764143_9
CAAX protease self-immunity
K07052
-
-
0.0000005516
62.0
View
HKD2_k127_7667607_0
Belongs to the PEP-utilizing enzyme family
K01006
-
2.7.9.1
8.35e-244
764.0
View
HKD2_k127_7667607_1
Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
K15987
-
3.6.1.1
7.234e-206
661.0
View
HKD2_k127_7667607_2
Belongs to the dGTPase family. Type 2 subfamily
K01129
-
3.1.5.1
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197
399.0
View
HKD2_k127_7673918_0
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K01952
-
6.3.5.3
2.207e-263
837.0
View
HKD2_k127_7673918_1
UvrD-like helicase C-terminal domain
K03657
-
3.6.4.12
4.489e-249
787.0
View
HKD2_k127_7673918_10
Phosphoribosylformylglycinamidine cyclo-ligase
K01933
-
6.3.3.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471
442.0
View
HKD2_k127_7673918_11
PFAM ABC transporter
K01995,K15783
GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039
3.5.4.44
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654
400.0
View
HKD2_k127_7673918_12
ABC transporter
K01996
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339
357.0
View
HKD2_k127_7673918_13
serine-type endopeptidase activity
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726
355.0
View
HKD2_k127_7673918_14
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237
357.0
View
HKD2_k127_7673918_15
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526
331.0
View
HKD2_k127_7673918_16
aminopeptidase activity
K19701,K19702
-
3.4.11.10,3.4.11.24,3.4.11.6
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954
313.0
View
HKD2_k127_7673918_17
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K01952
-
6.3.5.3
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003796
287.0
View
HKD2_k127_7673918_18
Domain of unknown function (DUF4445)
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000003592
254.0
View
HKD2_k127_7673918_19
Phosphatidylserine decarboxylase
K01613
-
4.1.1.65
0.00000000000000000000000000000000000000000000000000000000000000001528
239.0
View
HKD2_k127_7673918_2
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K01756
GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
4.3.2.2
1.961e-196
620.0
View
HKD2_k127_7673918_20
Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K11175
-
2.1.2.2
0.0000000000000000000000000000000000000000000000000000000000000007143
236.0
View
HKD2_k127_7673918_21
Receptor family ligand binding region
K01999
-
-
0.000000000000000000000000000000000000000000000000000002155
205.0
View
HKD2_k127_7673918_22
Diguanylate cyclase
-
-
-
0.000000000000000000000000000000000000000000000000000008523
209.0
View
HKD2_k127_7673918_23
calcium- and calmodulin-responsive adenylate cyclase activity
K08372
-
-
0.0000000000000000000000000000000000000127
162.0
View
HKD2_k127_7673918_24
Histidine kinase
-
-
-
0.000000000000000000000000000000000001206
158.0
View
HKD2_k127_7673918_25
Domain of unknown function (DUF1508)
K09946
-
-
0.00000000000000000000000000000000000307
141.0
View
HKD2_k127_7673918_26
response regulator
-
-
-
0.00000000000000000000000000000000001451
143.0
View
HKD2_k127_7673918_27
Domain of unknown function (DUF4126)
-
-
-
0.0000000000000000000000000000000001673
139.0
View
HKD2_k127_7673918_28
GAF domain
K02480
-
2.7.13.3
0.000000000000000000000000001083
129.0
View
HKD2_k127_7673918_29
Peptidoglycan-binding domain 1 protein
-
-
-
0.000000000000000000000000005629
126.0
View
HKD2_k127_7673918_3
Bifunctional purine biosynthesis protein PurH
K00602
-
2.1.2.3,3.5.4.10
4.127e-195
623.0
View
HKD2_k127_7673918_30
-
-
-
-
0.0000000000000000000000007776
110.0
View
HKD2_k127_7673918_31
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K01952
-
6.3.5.3
0.0000000000000000000005387
97.0
View
HKD2_k127_7673918_32
calcium- and calmodulin-responsive adenylate cyclase activity
-
-
-
0.0000000000000001114
90.0
View
HKD2_k127_7673918_33
-
-
-
-
0.00000000000001463
88.0
View
HKD2_k127_7673918_34
ACT domain protein
-
-
-
0.000000000004641
72.0
View
HKD2_k127_7673918_35
L,D-transpeptidase catalytic domain
-
-
-
0.0000000000315
73.0
View
HKD2_k127_7673918_36
Zn-finger in ubiquitin-hydrolases and other protein
-
-
-
0.00000000006933
63.0
View
HKD2_k127_7673918_38
Rhomboid family
K19225
-
3.4.21.105
0.00000000187
66.0
View
HKD2_k127_7673918_39
-
-
-
-
0.0000006677
52.0
View
HKD2_k127_7673918_4
Bacterial protein of unknown function (DUF853)
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701
615.0
View
HKD2_k127_7673918_40
Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase
K02619
-
4.1.3.38
0.000001926
59.0
View
HKD2_k127_7673918_5
Receptor family ligand binding region
K01999
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531
530.0
View
HKD2_k127_7673918_6
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K00764
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464
2.4.2.14
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626
546.0
View
HKD2_k127_7673918_7
Belongs to the binding-protein-dependent transport system permease family
K01998
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491
529.0
View
HKD2_k127_7673918_8
Belongs to the binding-protein-dependent transport system permease family
K01997
GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021
475.0
View
HKD2_k127_7673918_9
SAICAR synthetase
K01923
-
6.3.2.6
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145
439.0
View
HKD2_k127_7675724_0
ABC-type antimicrobial peptide transport system, permease component
K02004
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646
327.0
View
HKD2_k127_7675724_1
ABC transporter
K02003
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594
318.0
View
HKD2_k127_7675724_10
-
-
-
-
0.000001693
57.0
View
HKD2_k127_7675724_2
cheY-homologous receiver domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001343
295.0
View
HKD2_k127_7675724_3
zinc metallopeptidase
K06973
-
-
0.000000000000000000000000000000000000000000000000000000000000002266
224.0
View
HKD2_k127_7675724_4
Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
K03272
-
2.7.1.167,2.7.7.70
0.000000000000000000000000000000000000000000000000000000000002813
221.0
View
HKD2_k127_7675724_5
Glycosyltransferase family 9 (heptosyltransferase)
K02843
-
-
0.000000000000000000000000000000000000000000003986
179.0
View
HKD2_k127_7675724_6
Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
K03272
-
2.7.1.167,2.7.7.70
0.00000000000000000000000000000000000000000001938
167.0
View
HKD2_k127_7675724_7
-
-
-
-
0.00000000000000000000002806
108.0
View
HKD2_k127_7675724_8
Histidine kinase
-
-
-
0.000000000000000000008504
94.0
View
HKD2_k127_7675724_9
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
-
-
-
0.00000000001566
77.0
View
HKD2_k127_7699236_0
Belongs to the SEDS family
-
-
-
5.644e-248
795.0
View
HKD2_k127_7699236_1
Histidine kinase
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732
402.0
View
HKD2_k127_7699236_10
diguanylate cyclase
-
-
-
0.000000000000000000000000000000000000000000000001072
194.0
View
HKD2_k127_7699236_11
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
K02257
GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
2.5.1.141
0.00000000000000000000000000000000000004352
159.0
View
HKD2_k127_7699236_12
Protein of unknown function (DUF2662)
-
-
-
0.00000000000000000000000000000000003098
144.0
View
HKD2_k127_7699236_13
positive regulation of acetylcholine metabolic process
K06910
-
-
0.0000000000000000000000000000000001297
140.0
View
HKD2_k127_7699236_14
PFAM Response regulator receiver domain
K07658
-
-
0.0000000000000000000000000000002385
128.0
View
HKD2_k127_7699236_15
PFAM response regulator receiver
K02483,K07658,K07668
-
-
0.0000000000000000000000000005076
119.0
View
HKD2_k127_7699236_16
Protein of unknown function (DUF4446)
-
-
-
0.000000000000003418
83.0
View
HKD2_k127_7699236_17
Inner membrane component of T3SS, cytoplasmic domain
-
GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944
-
0.000000000000003534
80.0
View
HKD2_k127_7699236_18
-
-
-
-
0.0007
43.0
View
HKD2_k127_7699236_2
phosphatase 2C
K20074
-
3.1.3.16
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699
309.0
View
HKD2_k127_7699236_3
Kinase domain
K12132
-
2.7.11.1
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475
298.0
View
HKD2_k127_7699236_4
AIR carboxylase
K06898
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000008427
279.0
View
HKD2_k127_7699236_5
Belongs to the LarC family
K09121
-
4.99.1.12
0.00000000000000000000000000000000000000000000000000000000000000000000000000001328
274.0
View
HKD2_k127_7699236_6
endonuclease III
K03575
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000002753
264.0
View
HKD2_k127_7699236_7
Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000828
250.0
View
HKD2_k127_7699236_8
Kinase domain
K12132
-
2.7.11.1
0.0000000000000000000000000000000000000000000000000000000000000000000000254
264.0
View
HKD2_k127_7699236_9
Prephenate dehydratase
K04518,K14170
-
4.2.1.51,5.4.99.5
0.0000000000000000000000000000000000000000000000000000000000000000000003709
265.0
View
HKD2_k127_7724144_0
metal-dependent phosphohydrolase, 7TM intracellular region
K07037
-
-
0.0000000000000000000000000000000000000000000000000000005086
198.0
View
HKD2_k127_7724144_1
Diacylglycerol kinase
K00887,K00901
-
2.7.1.107,2.7.1.66
0.00000000000000000000000000000000000000000000000000201
190.0
View
HKD2_k127_7724144_2
Transporter associated domain
-
-
-
0.00000000000000000000000000000000000008553
149.0
View
HKD2_k127_7724144_3
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K07042
-
-
0.0000000000000000000000000000002201
128.0
View
HKD2_k127_7800383_0
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K03151
-
2.8.1.4
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009202
373.0
View
HKD2_k127_7800383_1
abc transporter
K01990
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008566
292.0
View
HKD2_k127_7800383_2
glycosyl transferase group 1
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000008301
257.0
View
HKD2_k127_7800383_3
Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
K03060
GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944
2.7.7.6
0.0000000002376
66.0
View
HKD2_k127_7800383_5
Essential for recycling GMP and indirectly, cGMP
K00942
GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657
2.7.4.8
0.0002316
45.0
View
HKD2_k127_7869565_0
Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K01875
-
6.1.1.11
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675
585.0
View
HKD2_k127_7869565_1
Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998
372.0
View
HKD2_k127_7869565_2
PFAM CO dehydrogenase acetyl-CoA synthase delta subunit, TIM barrel
K00197
-
2.1.1.245
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771
328.0
View
HKD2_k127_7869565_3
PFAM BadF BadG BcrA BcrD ATPase family
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000002908
259.0
View
HKD2_k127_7869565_4
Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
K03282
-
-
0.0000000000000000000000000000000000000000000000003962
179.0
View
HKD2_k127_7869565_5
PFAM Appr-1-p processing domain protein
-
-
-
0.000000000000000000000000000000000000000004305
161.0
View
HKD2_k127_7869565_6
4Fe-4S binding domain
-
-
-
0.0000000000000000000000000001043
128.0
View
HKD2_k127_7869565_7
Belongs to the sulfur carrier protein TusA family
K04085
-
-
0.00000000000000000000000002577
111.0
View
HKD2_k127_7893575_0
amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K01870
-
6.1.1.5
8.839e-215
682.0
View
HKD2_k127_7957091_0
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K01874
GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576
6.1.1.10
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877
563.0
View
HKD2_k127_7957091_1
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K04042
-
2.3.1.157,2.7.7.23
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032
482.0
View
HKD2_k127_7957091_10
ROK family
K00845
-
2.7.1.2
0.00000000000000000000000000000000000000000000000000001179
202.0
View
HKD2_k127_7957091_11
PFAM peptidase
K21471
-
-
0.0000000000000000000000000000000000000000000000000206
193.0
View
HKD2_k127_7957091_12
MobA-like NTP transferase domain
-
-
-
0.0000000000000000000000000000000000000000000001776
181.0
View
HKD2_k127_7957091_13
Histidine kinase
K10681
-
2.7.13.3
0.00000000000000000000000000000000000000000001067
181.0
View
HKD2_k127_7957091_14
G5 domain protein
-
-
-
0.000000000000000000000000000000000000005124
160.0
View
HKD2_k127_7957091_15
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K02897
GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.000000000000000000000000000000000003511
145.0
View
HKD2_k127_7957091_16
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K00919
-
2.7.1.148
0.00000000000000000000000000000000004731
149.0
View
HKD2_k127_7957091_17
PFAM NADPH-dependent FMN reductase
-
-
-
0.000000000000000000000000000001966
133.0
View
HKD2_k127_7957091_18
Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
K06412
GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934
-
0.000000000000000000000008768
104.0
View
HKD2_k127_7957091_19
Biofilm formation stimulator VEG
-
-
-
0.00000000000000000000003578
101.0
View
HKD2_k127_7957091_2
Domain of unknown function (DUF362)
K07138
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411
409.0
View
HKD2_k127_7957091_20
TIGRFAM looped-hinge helix DNA binding domain, AbrB family
K06284
-
-
0.00000000000000005958
85.0
View
HKD2_k127_7957091_22
Transcriptional regulator
-
-
-
0.00000000000008175
76.0
View
HKD2_k127_7957091_23
IrrE N-terminal-like domain
-
-
-
0.0000005349
58.0
View
HKD2_k127_7957091_24
Domain of unknown function (DUF4870)
-
-
-
0.0000007522
57.0
View
HKD2_k127_7957091_25
-
-
-
-
0.000003543
59.0
View
HKD2_k127_7957091_3
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K00948
-
2.7.6.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791
357.0
View
HKD2_k127_7957091_4
Hydrolase, TatD family
K03424
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000006478
249.0
View
HKD2_k127_7957091_5
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
K02528
-
2.1.1.182
0.0000000000000000000000000000000000000000000000000000000000000000000004166
254.0
View
HKD2_k127_7957091_6
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K07056
-
2.1.1.198
0.000000000000000000000000000000000000000000000000000000000000000001717
242.0
View
HKD2_k127_7957091_7
Response regulator receiver
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000002011
234.0
View
HKD2_k127_7957091_8
The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
K01056
-
3.1.1.29
0.00000000000000000000000000000000000000000000000000000000005194
210.0
View
HKD2_k127_7957091_9
PFAM metal-dependent phosphohydrolase HD sub domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000006452
224.0
View
HKD2_k127_7966807_0
Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
K00794
GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
2.5.1.78
0.000000000000000000000000000000000000000000000000000003738
192.0
View
HKD2_k127_7966807_1
TIGRFAM transcriptional regulator, Rrf2 family
-
-
-
0.000000000000000000000000003116
115.0
View
HKD2_k127_7997242_0
Telomere recombination
K04656
-
-
1.384e-221
717.0
View
HKD2_k127_7997242_1
hydrogenase expression formation protein HypD
K04654
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843
470.0
View
HKD2_k127_7997242_10
4Fe-4S ferredoxin
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000446
239.0
View
HKD2_k127_7997242_11
PFAM cobalamin (vitamin B12) biosynthesis CbiM protein
K02007
-
-
0.000000000000000000000000000000000000000000000000000102
198.0
View
HKD2_k127_7997242_12
Metal-dependent phosphohydrolase, HD region
-
-
-
0.000000000000000000000000000000000000000000000000001872
206.0
View
HKD2_k127_7997242_13
QueT transporter
-
-
-
0.000000000000000000000000000000000000000000000000004495
187.0
View
HKD2_k127_7997242_14
transcriptional regulator
K07722
GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141
-
0.000000000000000000000000000000000000000000000000004574
184.0
View
HKD2_k127_7997242_15
Belongs to the thioredoxin family
K03671
GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748
-
0.0000000000000000000000000000000000001316
144.0
View
HKD2_k127_7997242_16
PFAM GGDEF domain containing protein
K02488
-
2.7.7.65
0.00000000000000000000000000000001978
145.0
View
HKD2_k127_7997242_17
Calcineurin-like phosphoesterase superfamily domain
K07095
-
-
0.000000000000000000000000000006426
126.0
View
HKD2_k127_7997242_18
Cobalt ABC transporter
K02008
-
-
0.000000000000000000000000005822
127.0
View
HKD2_k127_7997242_19
membrane transporter protein
K07090
-
-
0.00000000000000000000001784
109.0
View
HKD2_k127_7997242_2
hydrogenase expression formation protein HypE
K04655
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128
449.0
View
HKD2_k127_7997242_20
COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
-
-
-
0.000000000000000000003939
104.0
View
HKD2_k127_7997242_21
hydrogenase assembly chaperone HypC HupF
K04653
-
-
0.0000000000000000001272
92.0
View
HKD2_k127_7997242_22
SMART Nucleotide binding protein, PINc
K07175
-
-
0.000000000000000002539
97.0
View
HKD2_k127_7997242_23
Domain present in phytochromes and cGMP-specific phosphodiesterases.
-
-
-
0.000000009225
57.0
View
HKD2_k127_7997242_24
Acetyltransferase (GNAT) family
K22477
-
2.3.1.1
0.00001397
57.0
View
HKD2_k127_7997242_25
-
-
-
-
0.00005518
49.0
View
HKD2_k127_7997242_26
Tetratricopeptide repeat
-
-
-
0.0006358
51.0
View
HKD2_k127_7997242_3
histidine kinase DNA gyrase B
K07704
-
2.7.13.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763
374.0
View
HKD2_k127_7997242_4
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K13810
-
2.2.1.2,5.3.1.9
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452
370.0
View
HKD2_k127_7997242_5
Glycosyltransferase like family 2
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918
354.0
View
HKD2_k127_7997242_6
Radical SAM superfamily
K04069
-
1.97.1.4
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076
353.0
View
HKD2_k127_7997242_7
ABC transporter
K02006,K02008
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000212
283.0
View
HKD2_k127_7997242_8
Pyridine nucleotide-disulphide oxidoreductase
K00384
-
1.8.1.9
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002366
290.0
View
HKD2_k127_7997242_9
response regulator receiver
K07705
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000003822
271.0
View
HKD2_k127_8016449_0
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K00600
-
2.1.2.1
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069
581.0
View
HKD2_k127_8016449_1
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K02835
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271
477.0
View
HKD2_k127_8016449_2
Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
K02493
-
2.1.1.297
0.000000000000000000000000000000000000000000000000000000000000000000000000000001323
273.0
View
HKD2_k127_8016449_3
Sua5 YciO YrdC YwlC family
K07566
-
2.7.7.87
0.00000000000000000000000000000000000000000000000000005331
194.0
View
HKD2_k127_8016449_4
Ribose 5-phosphate isomerase
K01808
-
5.3.1.6
0.0000000000000000000000000000000000000000000009042
173.0
View
HKD2_k127_8016449_5
Protein of unknown function (DUF1385)
-
-
-
0.0000000000000000000000000000000000000000000539
164.0
View
HKD2_k127_8016449_6
Toxic component of a toxin-antitoxin (TA) module
K07171
-
-
0.000000000000000000003284
100.0
View
HKD2_k127_8016449_7
Glycosyl hydrolase family 65, N-terminal domain
K15923
-
3.2.1.51
0.000000003523
57.0
View
HKD2_k127_8038014_0
Required for chromosome condensation and partitioning
K03529
-
-
2.293e-281
905.0
View
HKD2_k127_8038014_1
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
K09458
-
2.3.1.179
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413
488.0
View
HKD2_k127_8038014_10
PFAM DRTGG domain protein
K06873
-
-
0.000000000000000000000000000000000000000000000000000000000000000000133
243.0
View
HKD2_k127_8038014_11
Acyl transferase domain
K00645
-
2.3.1.39
0.0000000000000000000000000000000000000000000000000000004501
207.0
View
HKD2_k127_8038014_12
Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
K03685
GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363
3.1.26.3
0.0000000000000000000000000000000000000000000000005833
184.0
View
HKD2_k127_8038014_13
Carrier of the growing fatty acid chain in fatty acid biosynthesis
K02078
-
-
0.0000000000000000000000000009088
114.0
View
HKD2_k127_8038014_14
Belongs to the peptidase S26 family
K03100
-
3.4.21.89
0.000000000000000000004459
107.0
View
HKD2_k127_8038014_2
PFAM 2-nitropropane dioxygenase
K02371
-
1.3.1.9
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996
386.0
View
HKD2_k127_8038014_3
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K03106
-
3.6.5.4
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274
370.0
View
HKD2_k127_8038014_4
2-nitropropane dioxygenase
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119
353.0
View
HKD2_k127_8038014_5
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
K03110
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701
355.0
View
HKD2_k127_8038014_6
Acyl-CoA synthetase (NDP forming)
K09181
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517
336.0
View
HKD2_k127_8038014_7
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
K03621
-
2.3.1.15
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415
330.0
View
HKD2_k127_8038014_8
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K00648
-
2.3.1.180
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005838
329.0
View
HKD2_k127_8038014_9
reductase
K00059
-
1.1.1.100
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002061
288.0
View
HKD2_k127_8123097_0
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K01868
-
6.1.1.3
4.037e-275
859.0
View
HKD2_k127_8123097_1
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
K01547
-
3.6.3.12
2.024e-248
794.0
View
HKD2_k127_8123097_2
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
K01546
-
3.6.3.12
1.652e-212
676.0
View
HKD2_k127_8123097_3
Transcriptional regulatory protein, C terminal
K07667
-
-
0.0000000000000000000000000000000000000000000000000000000000000000006735
237.0
View
HKD2_k127_8123097_4
Histidine kinase
K07646
-
2.7.13.3
0.00000000000000000000000000000000000000000000000000002324
207.0
View
HKD2_k127_8123097_5
calcium- and calmodulin-responsive adenylate cyclase activity
K08372
-
-
0.00000000000000000000000000000000003345
154.0
View
HKD2_k127_8123097_6
Double zinc ribbon
-
-
-
0.00000000000000000000000000000000003412
139.0
View
HKD2_k127_8153823_0
Prophage cp4-57 regulatory
-
-
-
0.00000000000000000000000000000000000000000000001452
181.0
View
HKD2_k127_8153823_1
-
-
-
-
0.0000000000000000000000000000008289
123.0
View
HKD2_k127_827247_0
Belongs to the CarB family
K01955
-
6.3.5.5
9.852e-218
682.0
View
HKD2_k127_827247_1
Belongs to the CarA family
K01956
-
6.3.5.5
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775
459.0
View
HKD2_k127_827247_2
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
K01465
-
3.5.2.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396
341.0
View
HKD2_k127_8692266_0
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
K02519
-
-
2.291e-265
839.0
View
HKD2_k127_8692266_1
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
K01881
-
6.1.1.15
2.14e-224
711.0
View
HKD2_k127_8692266_10
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K00806
-
2.5.1.31
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000594
276.0
View
HKD2_k127_8692266_11
Glycosyl transferases group 1
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000002258
247.0
View
HKD2_k127_8692266_12
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
K02838
-
-
0.00000000000000000000000000000000000000000000000000000000000000005562
226.0
View
HKD2_k127_8692266_13
Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K03177
-
5.4.99.25
0.00000000000000000000000000000000000000000000000000000000000008008
235.0
View
HKD2_k127_8692266_14
DHHA1 domain
K06881
-
3.1.13.3,3.1.3.7
0.000000000000000000000000000000000000000000000000000000000001029
222.0
View
HKD2_k127_8692266_15
riboflavin biosynthesis protein
K11753
-
2.7.1.26,2.7.7.2
0.0000000000000000000000000000000000000000000000000000000001657
220.0
View
HKD2_k127_8692266_16
RIP metalloprotease RseP
K11749
-
-
0.000000000000000000000000000000000000000000000000000000015
216.0
View
HKD2_k127_8692266_17
Cytidylyltransferase family
K00981
-
2.7.7.41
0.0000000000000000000000000000000000000000000000001674
191.0
View
HKD2_k127_8692266_18
Condensation domain
-
-
-
0.00000000000000000000000000000000000000001567
171.0
View
HKD2_k127_8692266_19
-
-
-
-
0.00000000000000000000000000000000001302
142.0
View
HKD2_k127_8692266_2
Participates in both transcription termination and antitermination
K02600
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063
446.0
View
HKD2_k127_8692266_20
Required for maturation of 30S ribosomal subunits
K09748
-
-
0.000000000000000000000000000000001036
138.0
View
HKD2_k127_8692266_21
FMN binding
-
-
-
0.0000000000000000000000000000001926
132.0
View
HKD2_k127_8692266_22
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K02834
-
-
0.000000000000000000000001903
107.0
View
HKD2_k127_8692266_23
PFAM response regulator receiver
K07657
-
-
0.00000000000000000002011
100.0
View
HKD2_k127_8692266_24
Nucleic-acid-binding protein implicated in transcription termination
K02600,K07742
-
-
0.0000000000000000005488
89.0
View
HKD2_k127_8692266_3
Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
K00099
-
1.1.1.267
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061
411.0
View
HKD2_k127_8692266_4
PFAM Major Facilitator Superfamily
K08177
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218
396.0
View
HKD2_k127_8692266_5
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K03526
-
1.17.7.1,1.17.7.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018
379.0
View
HKD2_k127_8692266_6
Catalyzes the reversible phosphorylation of UMP to UDP
K09903
-
2.7.4.22
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627
346.0
View
HKD2_k127_8692266_7
Belongs to the universal ribosomal protein uS2 family
K02967
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599
320.0
View
HKD2_k127_8692266_8
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K02357
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745
301.0
View
HKD2_k127_8692266_9
Sigma-70, region 4
K02405
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007329
280.0
View
HKD2_k127_8693695_0
Provides the (R)-glutamate required for cell wall biosynthesis
K01776
-
5.1.1.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549
326.0
View
HKD2_k127_8693695_1
Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K00989
-
2.7.7.56
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268
299.0
View
HKD2_k127_8693695_2
catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
K03412
-
3.1.1.61,3.5.1.44
0.00000000000000000000000000000000000000000000000000000000000000001799
234.0
View
HKD2_k127_8693695_3
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K02428
-
3.6.1.66
0.0000000000000000000000000000000000000000000000000000008951
199.0
View
HKD2_k127_8693695_4
Metal-dependent hydrolase
-
GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267
-
0.00000000000000000000000000000001816
138.0
View
HKD2_k127_8991112_0
ATPase, P-type (transporting), HAD superfamily, subfamily IC
K17686
-
3.6.3.54
5.704e-242
786.0
View
HKD2_k127_8991112_1
PFAM Band 7 protein
-
-
-
1.423e-232
730.0
View
HKD2_k127_8991112_10
PFAM GCN5-related N-acetyltransferase
-
-
-
0.00000000007788
74.0
View
HKD2_k127_8991112_11
E1-E2 ATPase
K01533,K17686
-
3.6.3.4,3.6.3.54
0.0000000004387
72.0
View
HKD2_k127_8991112_12
-
-
-
-
0.0000000227
66.0
View
HKD2_k127_8991112_13
-
-
-
-
0.0000002583
58.0
View
HKD2_k127_8991112_2
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K01950
-
6.3.5.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575
558.0
View
HKD2_k127_8991112_3
DeoC/LacD family aldolase
K11645
-
4.1.2.13
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077
489.0
View
HKD2_k127_8991112_4
Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
K00895,K21071
-
2.7.1.11,2.7.1.90
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239
407.0
View
HKD2_k127_8991112_5
Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
K01962,K01963
-
2.1.3.15,6.4.1.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156
344.0
View
HKD2_k127_8991112_6
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K01963
-
2.1.3.15,6.4.1.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004578
289.0
View
HKD2_k127_8991112_7
Cytochrome C biogenesis protein transmembrane region
K02275,K09792,K17686
-
1.9.3.1,3.6.3.54
0.00000000000000000000000000000000000000002624
169.0
View
HKD2_k127_8991112_8
phosphorelay signal transduction system
K07658
-
-
0.00000000000000000000000002574
113.0
View
HKD2_k127_8991112_9
Cupredoxin-like domain
-
-
-
0.00000000001134
74.0
View
HKD2_k127_9022459_0
D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
K01621
-
4.1.2.22,4.1.2.9
0.0
1311.0
View
HKD2_k127_9022459_1
Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K00925
-
2.7.2.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848
392.0
View
HKD2_k127_9022459_10
-
-
-
-
0.0000000000000000000000000000003318
130.0
View
HKD2_k127_9022459_11
Zn-finger in ubiquitin-hydrolases and other protein
-
-
-
0.000000000000000000000000000006359
121.0
View
HKD2_k127_9022459_12
Sortase family
K07284
-
3.4.22.70
0.00000000000000000000000001063
122.0
View
HKD2_k127_9022459_13
Bacterial regulatory proteins, tetR family
-
-
-
0.0000000000000000000000005824
113.0
View
HKD2_k127_9022459_14
DNA-templated transcription, initiation
K03088
-
-
0.000000000000000000001204
110.0
View
HKD2_k127_9022459_15
Cobalamin B12-binding domain protein
-
-
-
0.000000000000000001129
96.0
View
HKD2_k127_9022459_16
META domain
K03668
-
-
0.000000087
64.0
View
HKD2_k127_9022459_2
MacB-like periplasmic core domain
K02004
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284
325.0
View
HKD2_k127_9022459_3
1,2-diacylglycerol 3-glucosyltransferase
K19002
-
2.4.1.337
0.0000000000000000000000000000000000000000000000000000000000000000000001122
262.0
View
HKD2_k127_9022459_4
Protein of unknown function DUF72
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000003165
250.0
View
HKD2_k127_9022459_5
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner
K09810
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000004693
244.0
View
HKD2_k127_9022459_6
ABC-type transport system involved in lipoprotein release permease component
K09808
-
-
0.0000000000000000000000000000000000000000000000000000000000000000002645
246.0
View
HKD2_k127_9022459_7
ATPases associated with a variety of cellular activities
K02003,K09810
-
-
0.00000000000000000000000000000000000000000000000000000000000000001065
232.0
View
HKD2_k127_9022459_8
Acetyltransferase (GNAT) domain
K03823
-
2.3.1.183
0.0000000000000000000000000000000000001401
149.0
View
HKD2_k127_9022459_9
PFAM Isoprenylcysteine carboxyl methyltransferase (ICMT) family
-
-
-
0.000000000000000000000000000000001377
138.0
View
HKD2_k127_9063833_0
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
K03695
-
-
0.0
1097.0
View
HKD2_k127_9063833_1
Heat shock 70 kDa protein
K04043
-
-
8.37e-301
938.0
View
HKD2_k127_9063833_10
Transcriptional regulator, MerR family
K13640
-
-
0.000000000000000000000000000609
119.0
View
HKD2_k127_9063833_11
4Fe-4S binding domain
-
-
-
0.0000000000000000000009833
96.0
View
HKD2_k127_9063833_12
helix_turn_helix multiple antibiotic resistance protein
-
-
-
0.0000006176
57.0
View
HKD2_k127_9063833_13
-
-
-
-
0.000007713
58.0
View
HKD2_k127_9063833_2
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K01338
-
3.4.21.53
2.199e-227
715.0
View
HKD2_k127_9063833_3
DNA ligase
K01971
-
6.5.1.1
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416
348.0
View
HKD2_k127_9063833_4
ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
K03686
GO:0006457,GO:0008150,GO:0009987
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717
321.0
View
HKD2_k127_9063833_5
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
K10979
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000006469
258.0
View
HKD2_k127_9063833_6
NAD-dependent epimerase dehydratase
K01784
-
5.1.3.2
0.0000000000000000000000000000000000000000000000000000000000000000002027
241.0
View
HKD2_k127_9063833_7
CMP dCMP deaminase, zinc-binding
K01487
-
3.5.4.3
0.000000000000000000000000000000000000000000000000000000000000006315
220.0
View
HKD2_k127_9063833_8
Sortase family
-
-
-
0.00000000000000000000000000000000001626
145.0
View
HKD2_k127_9063833_9
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K03687
-
-
0.00000000000000000000000000000000007011
140.0
View
HKD2_k127_9166368_0
elongation factor G
K02355
-
-
1.144e-255
808.0
View
HKD2_k127_9166368_1
Oxidoreductase NAD-binding domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991
458.0
View
HKD2_k127_9166368_2
Nickel-dependent hydrogenase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639
426.0
View
HKD2_k127_9166368_3
4Fe-4S dicluster domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816
342.0
View
HKD2_k127_9166368_4
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily
K03615
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000006318
272.0
View
HKD2_k127_9166368_5
NADH ubiquinone oxidoreductase, 20 Kd subunit
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000184
257.0
View
HKD2_k127_9166368_6
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
K00940
-
2.7.4.6
0.00000000000000000000000000000000000000000000000000000002171
201.0
View
HKD2_k127_9166368_7
Tetratricopeptide repeat
-
-
-
0.000000000000000000000000000000000000000000000001447
190.0
View
HKD2_k127_9166368_8
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K01802,K03768
-
5.2.1.8
0.000000000000000000000000000000000002308
151.0
View
HKD2_k127_9169146_0
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K03798
-
-
6.869e-230
729.0
View
HKD2_k127_9169146_1
PFAM ABC transporter related
K01995
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758
312.0
View
HKD2_k127_9169146_10
Histidine kinase
K02480
-
2.7.13.3
0.0000000000000000000000000000000000000001314
166.0
View
HKD2_k127_9169146_11
Tim44
-
-
-
0.000000000000000000004979
105.0
View
HKD2_k127_9169146_12
Flp/Fap pilin component
K02651
-
-
0.000000001739
63.0
View
HKD2_k127_9169146_13
Flp/Fap pilin component
K02651
-
-
0.00000195
59.0
View
HKD2_k127_9169146_14
Tim44
-
-
-
0.000009277
57.0
View
HKD2_k127_9169146_2
ATPases associated with a variety of cellular activities
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931
302.0
View
HKD2_k127_9169146_3
Branched-chain amino acid transport system / permease component
K01997
GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000007361
282.0
View
HKD2_k127_9169146_4
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
K04075
-
6.3.4.19
0.000000000000000000000000000000000000000000000000000000000000000000000000001941
271.0
View
HKD2_k127_9169146_5
Branched-chain amino acid transport system / permease component
K01998
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000001944
261.0
View
HKD2_k127_9169146_6
SPFH domain-Band 7 family
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000114
244.0
View
HKD2_k127_9169146_7
Belongs to the purine pyrimidine phosphoribosyltransferase family
K00760
-
2.4.2.8
0.000000000000000000000000000000000000000000000000000000000000000000663
244.0
View
HKD2_k127_9169146_8
Amidohydrolase family
K12960,K20810
-
3.5.4.28,3.5.4.31,3.5.4.40
0.000000000000000000000000000000000000000000000002416
191.0
View
HKD2_k127_9169146_9
response regulator
-
-
-
0.00000000000000000000000000000000000000000000009356
187.0
View
HKD2_k127_9343739_0
ATP dependent DNA ligase domain protein
K01971
-
6.5.1.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000883
558.0
View
HKD2_k127_9343739_1
MacB-like periplasmic core domain
K02004
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589
526.0
View
HKD2_k127_9343739_2
RmuC family
K09760
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628
417.0
View
HKD2_k127_9343739_3
ATPases associated with a variety of cellular activities
K02003
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927
300.0
View
HKD2_k127_9343739_4
Iron-binding zinc finger CDGSH type
-
-
-
0.0000000000000000000000000000000000000000009157
167.0
View
HKD2_k127_9343739_5
Belongs to the small heat shock protein (HSP20) family
K13993
-
-
0.00000000000000000000000000308
116.0
View
HKD2_k127_9343739_6
-
-
-
-
0.000000000000000000002944
97.0
View
HKD2_k127_9343739_7
it plays a direct role in the translocation of protons across the membrane
K02108
-
-
0.0000000000000000001147
101.0
View
HKD2_k127_9343739_8
conserved protein (DUF2249)
-
-
-
0.000000001735
64.0
View
HKD2_k127_9376687_0
Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K03655
GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494
3.6.4.12
1.386e-195
631.0
View
HKD2_k127_9376687_1
DAK2 domain fusion protein YloV
K07030
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633
505.0
View
HKD2_k127_9376687_10
Belongs to the bacterial ribosomal protein bL28 family
K02902
-
-
0.00000000000000000000004937
101.0
View
HKD2_k127_9376687_11
Belongs to the bacterial ribosomal protein bL32 family
K02911
-
-
0.000000000000001168
80.0
View
HKD2_k127_9376687_12
Acetyltransferase (GNAT) domain
K03830
-
-
0.000000000000001187
86.0
View
HKD2_k127_9376687_13
cluster protein-associated redox disulfide domain protein
-
-
-
0.0001376
51.0
View
HKD2_k127_9376687_2
PFAM CoA-binding domain protein
K01905,K22224
-
6.2.1.13
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256
307.0
View
HKD2_k127_9376687_3
Uncharacterised protein, DegV family COG1307
-
-
-
0.0000000000000000000000000000000000000000000000000000004966
206.0
View
HKD2_k127_9376687_4
Domain present in phytochromes and cGMP-specific phosphodiesterases.
-
-
-
0.0000000000000000000000000000000000000000000000000000316
203.0
View
HKD2_k127_9376687_5
Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K00954
-
2.7.7.3
0.0000000000000000000000000000000000000000000000000002787
189.0
View
HKD2_k127_9376687_6
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
-
-
-
0.0000000000000000000000000000000000000000003238
162.0
View
HKD2_k127_9376687_7
Conserved hypothetical protein 95
K08316
-
2.1.1.171
0.00000000000000000000000000000000007494
142.0
View
HKD2_k127_9376687_8
Asp23 family, cell envelope-related function
-
-
-
0.00000000000000000000000000000002548
132.0
View
HKD2_k127_9376687_9
acr, cog1399
K07040
-
-
0.000000000000000000000000009765
117.0
View
HKD2_k127_9441451_0
Aldehyde ferredoxin oxidoreductase, N-terminal domain
K03738
-
1.2.7.5
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625
514.0
View
HKD2_k127_9441451_1
Class ii aldolase
K01628,K18847
-
2.2.1.8,4.1.2.17
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843
422.0
View
HKD2_k127_9606823_0
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K03215
-
2.1.1.190
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171
416.0
View
HKD2_k127_9606823_1
Type II/IV secretion system protein
K02669
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429
416.0
View
HKD2_k127_9606823_10
Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
K08591
-
2.3.1.15
0.00000000000000000001804
106.0
View
HKD2_k127_9606823_11
Cytochrome b5-like Heme/Steroid binding domain
-
-
-
0.00000000000000002081
87.0
View
HKD2_k127_9606823_12
4Fe-4S ferredoxin iron-sulfur binding domain protein
-
-
-
0.00000000000000009005
81.0
View
HKD2_k127_9606823_13
elongation factor G
K02355
-
-
0.000002219
50.0
View
HKD2_k127_9606823_2
GlcNAc-PI de-N-acetylase
K01463
-
-
0.00000000000000000000000000000000000000000000000000000001215
209.0
View
HKD2_k127_9606823_3
Involved in cell wall
K00721
-
2.4.1.83
0.000000000000000000000000000000000000000000000000000001541
207.0
View
HKD2_k127_9606823_4
Diacylglycerol kinase catalytic domain
K07029
-
2.7.1.107
0.00000000000000000000000000000000000000000000000009682
191.0
View
HKD2_k127_9606823_5
-
-
-
-
0.000000000000000000000000000000000000000000003152
187.0
View
HKD2_k127_9606823_6
Haloacid dehalogenase-like hydrolase
K07025
-
-
0.000000000000000000000000000000000000000001293
166.0
View
HKD2_k127_9606823_7
COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
K10914
-
-
0.00000000000000000000000000000007512
134.0
View
HKD2_k127_9606823_8
OsmC-like protein
K07397
-
-
0.00000000000000000000000000000008956
130.0
View
HKD2_k127_9606823_9
GDSL-like Lipase/Acylhydrolase family
-
-
-
0.000000000000000000000000007846
119.0
View
HKD2_k127_9673158_0
Belongs to the argininosuccinate synthase family. Type 1 subfamily
K01940
-
6.3.4.5
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028
589.0
View
HKD2_k127_9673158_1
Argininosuccinate lyase C-terminal
K01755
-
4.3.2.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594
544.0
View
HKD2_k127_9673158_10
Belongs to the DNA glycosylase MPG family
K03652
-
3.2.2.21
0.0000000000000000000000000000000000000000006042
167.0
View
HKD2_k127_9673158_2
penicillin-binding protein, 1A family
K05366
-
2.4.1.129,3.4.16.4
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431
473.0
View
HKD2_k127_9673158_3
PFAM peptidase U32
K08303
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173
447.0
View
HKD2_k127_9673158_4
N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K00821
GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363
2.6.1.11,2.6.1.17
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888
404.0
View
HKD2_k127_9673158_5
Belongs to the acetylglutamate kinase family. ArgB subfamily
K00930
-
2.7.2.8
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263
332.0
View
HKD2_k127_9673158_6
PFAM NIF3 (NGG1p interacting factor 3)
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169
329.0
View
HKD2_k127_9673158_7
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
K00611,K09065,K13252
-
2.1.3.3,2.1.3.6,2.1.3.9
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577
312.0
View
HKD2_k127_9673158_8
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K00620
-
2.3.1.1,2.3.1.35
0.0000000000000000000000000000000000000000000000000000000000000000000000001968
254.0
View
HKD2_k127_9673158_9
Regulates arginine biosynthesis genes
K03402
-
-
0.0000000000000000000000000000000000000000001211
163.0
View
HKD2_k127_9806303_0
Arginyl-tRNA synthetase
K01887
-
6.1.1.19
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562
602.0
View
HKD2_k127_9806303_1
Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
K01586
-
4.1.1.20
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847
364.0
View
HKD2_k127_9806303_2
-
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000255
258.0
View
HKD2_k127_9806303_3
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
K00783
-
2.1.1.177
0.0000000000000000000000000000000000000000000000002421
180.0
View
HKD2_k127_9806303_4
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K00343
-
1.6.5.3
0.000000000000003584
88.0
View
HKD2_k127_9806303_5
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K00337
-
1.6.5.3
0.000000000002267
73.0
View
HKD2_k127_9806303_6
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K00340,K05576
-
1.6.5.3
0.0000143
51.0
View
