Overview

ID MAG01810
Name HKD2_bin.66
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Bacillota
Class Bacilli
Order Bacillales_B
Family DSM-1321
Genus Peribacillus
Species
Assembly information
Completeness (%) 95.19
Contamination (%) 3.3
GC content (%) 36.0
N50 (bp) 8,372
Genome size (bp) 3,415,957

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3556

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10006706_0 Putative multidrug resistance efflux transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 434.0
HKD2_k127_10006706_1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 316.0
HKD2_k127_10006706_2 GCN5 family acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 308.0
HKD2_k127_1002294_0 YhgE Pip N-terminal domain protein K01421 - - 3.41e-263 829.0
HKD2_k127_1002294_1 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 1.313e-205 644.0
HKD2_k127_1002294_10 transporter (ATP-binding protein) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 406.0
HKD2_k127_1002294_11 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 401.0
HKD2_k127_1002294_12 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K01802,K07533 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 373.0
HKD2_k127_1002294_13 Catalyzes the synthesis of activated sulfate K00860 GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 353.0
HKD2_k127_1002294_14 Negative regulator of protease production and sporulation K09682 GO:0000003,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 329.0
HKD2_k127_1002294_15 Transcriptional regulator K09017 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 302.0
HKD2_k127_1002294_16 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 285.0
HKD2_k127_1002294_17 Sirohydrochlorin ferrochelatase K03794 - 4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007473 276.0
HKD2_k127_1002294_18 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002239 263.0
HKD2_k127_1002294_19 enzyme involved in biosynthesis of extracellular polysaccharides K21481 GO:0005575,GO:0016020 1.14.99.57 0.0000000000000000000000000000000000000000000000000000000000000000001994 233.0
HKD2_k127_1002294_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 8.996e-200 625.0
HKD2_k127_1002294_20 YtxH-like protein - - - 0.00000000000000000000000000000000005323 137.0
HKD2_k127_1002294_22 - - - - 0.0000000000000000002721 91.0
HKD2_k127_1002294_23 YhfH-like protein - - - 0.00000000000009024 72.0
HKD2_k127_1002294_25 - - - - 0.00000007278 55.0
HKD2_k127_1002294_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 4.668e-199 622.0
HKD2_k127_1002294_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 586.0
HKD2_k127_1002294_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 530.0
HKD2_k127_1002294_6 ABC transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 512.0
HKD2_k127_1002294_7 Belongs to the precorrin methyltransferase family K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008499 437.0
HKD2_k127_1002294_8 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 422.0
HKD2_k127_1002294_9 COG4208 ABC-type sulfate transport system, permease component K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 409.0
HKD2_k127_10043581_0 import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 355.0
HKD2_k127_10043581_1 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004001 275.0
HKD2_k127_10043581_2 Pfam:AHS2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006131 249.0
HKD2_k127_10043581_3 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000001145 248.0
HKD2_k127_10043581_4 Bacterial regulatory proteins, lacI family K02529 - - 0.00000000000000000000000000000000000000000000000000000000000005247 226.0
HKD2_k127_10043581_5 Pfam:AHS1 K06351 - - 0.000000000000000000000000000000000000000000000002371 182.0
HKD2_k127_10043581_6 Periplasmic binding protein LacI transcriptional regulator K11930 - - 0.0000001587 55.0
HKD2_k127_1007868_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 3.861e-209 656.0
HKD2_k127_1007868_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 8.279e-204 639.0
HKD2_k127_1007868_10 COG0110 Acetyltransferase (isoleucine patch superfamily) K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 280.0
HKD2_k127_1007868_11 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001095 276.0
HKD2_k127_1007868_12 belongs to the PRA-CH family K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000004104 180.0
HKD2_k127_1007868_13 belongs to the PRA-CH family K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000002331 145.0
HKD2_k127_1007868_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 471.0
HKD2_k127_1007868_3 COG0370 Fe2 transport system protein B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 451.0
HKD2_k127_1007868_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 437.0
HKD2_k127_1007868_5 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 424.0
HKD2_k127_1007868_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 384.0
HKD2_k127_1007868_7 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 360.0
HKD2_k127_1007868_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 350.0
HKD2_k127_1007868_9 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool K06019 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 289.0
HKD2_k127_10108778_0 Acetyl-CoA hydrolase/transferase N-terminal domain K18122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 463.0
HKD2_k127_10108778_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 316.0
HKD2_k127_10108778_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000804 208.0
HKD2_k127_10108778_3 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000006651 193.0
HKD2_k127_10108778_4 Acetyl-CoA hydrolase/transferase C-terminal domain K18122 - - 0.0000000000000003482 78.0
HKD2_k127_10126803_0 Multidrug efflux pump K03327 GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - 1.86e-209 659.0
HKD2_k127_10126803_1 Histidine kinase - - - 1.426e-208 658.0
HKD2_k127_10126803_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 591.0
HKD2_k127_10126803_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 310.0
HKD2_k127_10126803_4 COG0071 Molecular chaperone (small heat shock protein) - - - 0.000000000000000000000000000000000000000001247 160.0
HKD2_k127_10126803_5 YtkA-like - - - 0.0000000000000000000000000000000000000008378 151.0
HKD2_k127_10139322_0 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 591.0
HKD2_k127_10139322_1 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 580.0
HKD2_k127_10139322_10 domain, Protein K15125 - - 0.0000001166 54.0
HKD2_k127_10139322_2 Polysaccharide deacetylase K22278 GO:0005575,GO:0016020 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 459.0
HKD2_k127_10139322_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 449.0
HKD2_k127_10139322_4 reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 435.0
HKD2_k127_10139322_5 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 364.0
HKD2_k127_10139322_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000004569 72.0
HKD2_k127_10139322_7 - - - - 0.0000000000001318 72.0
HKD2_k127_10139322_8 LXG domain of WXG superfamily - - - 0.00000000001811 66.0
HKD2_k127_10139322_9 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000009497 59.0
HKD2_k127_10188490_0 Diguanylate cyclase - - - 2.102e-222 708.0
HKD2_k127_10188490_1 Belongs to the methyltransferase superfamily K07444 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - 3.386e-216 674.0
HKD2_k127_10190896_0 HD domain - - - 2.363e-271 846.0
HKD2_k127_10190896_1 - - - - 0.0000004722 51.0
HKD2_k127_10190896_2 - - - - 0.000003682 48.0
HKD2_k127_10197447_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 2.656e-288 891.0
HKD2_k127_10197447_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 7.842e-284 877.0
HKD2_k127_10197447_10 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 376.0
HKD2_k127_10197447_11 helix_turn_helix, arabinose operon control protein K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 344.0
HKD2_k127_10197447_12 helix_turn_helix, arabinose operon control protein K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 332.0
HKD2_k127_10197447_13 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009743 318.0
HKD2_k127_10197447_14 GPR1/FUN34/yaaH family K07034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 320.0
HKD2_k127_10197447_15 Putative rRNA methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 294.0
HKD2_k127_10197447_16 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 287.0
HKD2_k127_10197447_17 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002665 255.0
HKD2_k127_10197447_18 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001479 218.0
HKD2_k127_10197447_19 MarR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000001811 200.0
HKD2_k127_10197447_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 9.587e-230 716.0
HKD2_k127_10197447_20 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000009515 189.0
HKD2_k127_10197447_21 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000001063 171.0
HKD2_k127_10197447_22 GIY-YIG catalytic domain - - - 0.000000000000000000000000000000000000000001662 159.0
HKD2_k127_10197447_23 - - - - 0.000000000000000000000000000000000000000008002 156.0
HKD2_k127_10197447_24 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000000000000000005352 151.0
HKD2_k127_10197447_25 Protein of unknown function (DUF2584) - - - 0.00000000000000000000000000000001135 128.0
HKD2_k127_10197447_26 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.000000000000000000000000000001053 122.0
HKD2_k127_10197447_27 Uncharacterized protein conserved in bacteria (DUF2187) - - - 0.0000000000000003239 83.0
HKD2_k127_10197447_28 - - - - 0.0000000000000009243 79.0
HKD2_k127_10197447_3 Fe-S oxidoreductase K07139 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 4.89e-197 615.0
HKD2_k127_10197447_4 hydrocarbon binding protein (contains V4R domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 568.0
HKD2_k127_10197447_5 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 540.0
HKD2_k127_10197447_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 529.0
HKD2_k127_10197447_7 Alpha beta hydrolase K01048 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 479.0
HKD2_k127_10197447_8 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 474.0
HKD2_k127_10197447_9 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 430.0
HKD2_k127_10200503_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 544.0
HKD2_k127_10200503_1 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 464.0
HKD2_k127_10200503_2 Biotin biosynthesis protein K03523 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 294.0
HKD2_k127_10200503_3 Putative zincin peptidase - - - 0.000000000000000000000000004403 116.0
HKD2_k127_1064468_0 STAS domain K17763 - - 7.019e-311 962.0
HKD2_k127_1064468_1 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 417.0
HKD2_k127_1064468_2 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 406.0
HKD2_k127_1064468_3 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 367.0
HKD2_k127_1064468_4 Putative inner membrane exporter, YdcZ K09936 - - 0.0000000000000000000000000000000000000000000000000000000003934 205.0
HKD2_k127_1064468_5 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase) K17752 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000004627 197.0
HKD2_k127_1064468_6 chemotaxis protein K06595 - - 0.000000000000000000000000000000000003044 144.0
HKD2_k127_1064468_7 FeoA K04758 - - 0.0000001587 55.0
HKD2_k127_1089065_0 Domain of unknown function (DUF2935) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 512.0
HKD2_k127_1089065_1 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 325.0
HKD2_k127_1089065_2 Required for disulfide bond formation in some proteins K03611 - - 0.0000000000000000000000000000000000000000000000000000000000002103 214.0
HKD2_k127_1089065_3 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000002101 191.0
HKD2_k127_1134631_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1352.0
HKD2_k127_1134631_1 Acyl-CoA dehydrogenase, middle domain - - - 1.831e-224 698.0
HKD2_k127_1134631_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 567.0
HKD2_k127_1134631_3 Belongs to the enoyl-CoA hydratase isomerase family K07546,K08299,K15866 - 4.2.1.149,5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001226 259.0
HKD2_k127_1134631_4 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000009939 149.0
HKD2_k127_115913_0 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 327.0
HKD2_k127_115913_1 Non-histone chromosomal protein MC1 - - - 0.00000000000000000000000000000000000000000003552 162.0
HKD2_k127_115913_2 SpoIIAA-like - - - 0.000000000000000000000000000000001001 133.0
HKD2_k127_1169865_0 COG2309 Leucyl aminopeptidase (aminopeptidase T) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 601.0
HKD2_k127_1169865_1 HI0933-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 309.0
HKD2_k127_1169865_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.00000000000000000000000000000000000000000000000000000000000000000000001207 244.0
HKD2_k127_1169865_3 - - - - 0.000000000000000000000000000000000000000001448 163.0
HKD2_k127_1169865_4 PAP2 superfamily - - - 0.000002064 51.0
HKD2_k127_1183839_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 564.0
HKD2_k127_1183839_1 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 469.0
HKD2_k127_1183839_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 428.0
HKD2_k127_1183839_3 Glycosyltransferase like family 2 K16698 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 333.0
HKD2_k127_1183839_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000005466 182.0
HKD2_k127_1183839_5 Transcriptional regulator - - - 0.0000000001164 64.0
HKD2_k127_1285023_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 316.0
HKD2_k127_1287370_0 amino acid K11733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 573.0
HKD2_k127_1287370_1 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 413.0
HKD2_k127_1287370_2 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 294.0
HKD2_k127_1287370_3 general stress protein - - - 0.0000000000000000000000006601 104.0
HKD2_k127_1287370_4 general stress protein - - - 0.00000000000005072 72.0
HKD2_k127_1306186_0 Ribonuclease H-like K09776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 301.0
HKD2_k127_1306186_1 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 259.0
HKD2_k127_1306186_2 chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001303 249.0
HKD2_k127_1306186_3 response regulator K03413 - - 0.00000000000000000000000000000000000000000000000000000000009767 205.0
HKD2_k127_1306186_4 inhibitor of MCP methylation, homolog of CheC K03409 - - 0.000000000000000000000000000000000000000000000000000006336 194.0
HKD2_k127_1306186_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000001365 178.0
HKD2_k127_1306186_6 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains - - - 0.0006968 44.0
HKD2_k127_1315760_0 transmembrane signaling receptor activity K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004308 258.0
HKD2_k127_1315760_1 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000001129 211.0
HKD2_k127_1315760_2 prohibitin homologues - - - 0.0000000000000000007464 85.0
HKD2_k127_1319233_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0 1194.0
HKD2_k127_1319233_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1176.0
HKD2_k127_1319233_10 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 481.0
HKD2_k127_1319233_11 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 477.0
HKD2_k127_1319233_12 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA) K06411 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 364.0
HKD2_k127_1319233_13 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006566 277.0
HKD2_k127_1319233_14 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000000000000000000000001922 218.0
HKD2_k127_1319233_15 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000008315 169.0
HKD2_k127_1319233_16 ribosomal protein - - - 0.0000000000000000000000000000000000000000000002299 168.0
HKD2_k127_1319233_17 protein conserved in bacteria K09764 - - 0.000000000000000000000000000000000000000000001124 166.0
HKD2_k127_1319233_18 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.000000000000000000000000000000000000000002228 156.0
HKD2_k127_1319233_19 YlmC YmxH family - - - 0.0000000000000000000000000000000003704 134.0
HKD2_k127_1319233_2 Participates in both transcription termination and antitermination K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 1.239e-210 657.0
HKD2_k127_1319233_20 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00001434 48.0
HKD2_k127_1319233_21 - - - - 0.00009106 46.0
HKD2_k127_1319233_3 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 2.975e-210 659.0
HKD2_k127_1319233_4 Belongs to the peptidase M16 family - - - 1.312e-209 657.0
HKD2_k127_1319233_5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K03763 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 1.002e-205 641.0
HKD2_k127_1319233_6 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 596.0
HKD2_k127_1319233_7 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177,K03483 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 501.0
HKD2_k127_1319233_8 Dipicolinate synthase subunit A K06410 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 500.0
HKD2_k127_1319233_9 Sporulation protein, polysaccharide deacetylase - GO:0005575,GO:0016020 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 488.0
HKD2_k127_1367964_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K20428 - 2.6.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 327.0
HKD2_k127_1367964_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001873 253.0
HKD2_k127_1367964_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000004335 224.0
HKD2_k127_1385822_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 457.0
HKD2_k127_1385822_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 430.0
HKD2_k127_1385822_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 378.0
HKD2_k127_1385822_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 327.0
HKD2_k127_1385822_4 Bacterial regulatory proteins, gntR family - - - 0.000000000000000000000000000000000000000000000003294 175.0
HKD2_k127_1385822_5 - - - - 0.0000000000000000000000000000000002257 135.0
HKD2_k127_139179_0 Methionine synthase K00548 - 2.1.1.13 0.0 1939.0
HKD2_k127_139179_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) K00164 GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 0.0 1014.0
HKD2_k127_139179_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001547 284.0
HKD2_k127_139179_11 deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006733 280.0
HKD2_k127_139179_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009161 275.0
HKD2_k127_139179_13 Domain of unknown function (DUF4870) K09940 - - 0.000000000000000000000000000000000000000002492 158.0
HKD2_k127_139179_14 - - - - 0.0008562 43.0
HKD2_k127_139179_2 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 5.651e-264 826.0
HKD2_k127_139179_3 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00105,K00111 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 8.421e-200 636.0
HKD2_k127_139179_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 497.0
HKD2_k127_139179_5 ATP-dependent DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 453.0
HKD2_k127_139179_6 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 448.0
HKD2_k127_139179_7 ATP-dependent DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 349.0
HKD2_k127_139179_8 Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 318.0
HKD2_k127_139179_9 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 291.0
HKD2_k127_1405667_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 2.936e-243 753.0
HKD2_k127_1405667_1 GDP-mannose 4,6 dehydratase - - - 0.0000000000000000000002902 97.0
HKD2_k127_1405667_2 Spore germination protein K06295,K06310 - - 0.000000007425 61.0
HKD2_k127_14146_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 584.0
HKD2_k127_14146_1 GDP-mannose 4,6 dehydratase K15856 - 1.1.1.281 0.000000000000000002873 85.0
HKD2_k127_14146_2 Methyltransferase domain - - - 0.0000000000000002477 81.0
HKD2_k127_1428967_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001742 244.0
HKD2_k127_1428967_1 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000002798 207.0
HKD2_k127_1428967_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000009822 81.0
HKD2_k127_1451135_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02827 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901564,GO:1902600 1.10.3.12 8.423e-314 969.0
HKD2_k127_1451135_1 Belongs to the aspartokinase family K00928 GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 9.04e-228 711.0
HKD2_k127_1451135_2 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I K02826 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600 1.10.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 392.0
HKD2_k127_1451135_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 374.0
HKD2_k127_1451135_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 335.0
HKD2_k127_1451135_5 LuxR family transcriptional regulator K02479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 303.0
HKD2_k127_1470784_0 Putative glucoamylase - - - 0.0 2275.0
HKD2_k127_1470784_1 amino acid activation for nonribosomal peptide biosynthetic process K20951 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 509.0
HKD2_k127_1470784_2 - - - - 0.000000000000000001288 99.0
HKD2_k127_147613_0 uV damage repair endonuclease K13281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 475.0
HKD2_k127_147613_1 Domain of unknown function (DUF1906) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 288.0
HKD2_k127_147613_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 0.000000000000000000000000004667 113.0
HKD2_k127_147613_3 Belongs to the ClpA ClpB family K03697,K04086 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000002743 99.0
HKD2_k127_1478982_0 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 5.285e-238 741.0
HKD2_k127_1478982_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 4.994e-232 720.0
HKD2_k127_1478982_10 - - - - 0.0000000000000000000000000000000000000000000000000000007297 195.0
HKD2_k127_1478982_11 - - - - 0.000000000000000004754 88.0
HKD2_k127_1478982_12 - - - - 0.0000000002756 63.0
HKD2_k127_1478982_14 Phospholipase_D-nuclease N-terminal - - - 0.0003683 45.0
HKD2_k127_1478982_2 Cysteine desulfurase K04487 - 2.8.1.7 7.362e-206 645.0
HKD2_k127_1478982_3 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 366.0
HKD2_k127_1478982_4 COG3344 Retron-type reverse transcriptase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 332.0
HKD2_k127_1478982_5 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 302.0
HKD2_k127_1478982_6 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 293.0
HKD2_k127_1478982_7 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004 267.0
HKD2_k127_1478982_8 Transcriptional regulator K17472 GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0032991,GO:0032993,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044212,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0071840,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001138 260.0
HKD2_k127_1478982_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002232 231.0
HKD2_k127_1493805_0 COG1112 Superfamily I DNA and RNA helicases and helicase subunits - - - 1.275e-318 990.0
HKD2_k127_1493805_1 oligoendopeptidase F K08602 - - 1.601e-314 970.0
HKD2_k127_1493805_2 COG0147 Anthranilate para-aminobenzoate synthases component I K01665,K03342,K13950 - 2.6.1.85,4.1.3.38 3.928e-230 725.0
HKD2_k127_1493805_3 Belongs to the serine threonine dehydratase family. DsdA subfamily K01753 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008721,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.3.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 603.0
HKD2_k127_1493805_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 492.0
HKD2_k127_1493805_5 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 334.0
HKD2_k127_1493805_6 - - - - 0.00001208 48.0
HKD2_k127_149861_0 Dynamin family - GO:0000910,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022402,GO:0022607,GO:0031224,GO:0032506,GO:0044085,GO:0044425,GO:0051301,GO:0071840,GO:0090529 - 6.911e-237 745.0
HKD2_k127_149861_1 Cache domain - - - 8.887e-194 617.0
HKD2_k127_149861_2 Naringenin-chalcone synthase K16167 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 560.0
HKD2_k127_149861_3 protein conserved in bacteria K16168 - - 0.00000000000000000000000000000000000000000000000000000000000000000003745 236.0
HKD2_k127_149861_4 Chemotaxis phosphatase CheX K03409 - - 0.0000000000000000000000000000000000000000000000000002241 188.0
HKD2_k127_149861_5 RNA-directed DNA polymerase (reverse transcriptase) - - - 0.00000001333 56.0
HKD2_k127_1525806_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K01817 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 414.0
HKD2_k127_1525806_1 Inositol monophosphatase K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 385.0
HKD2_k127_1525806_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 372.0
HKD2_k127_1525806_3 Belongs to the UPF0637 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 288.0
HKD2_k127_1525806_5 Family of unknown function (DUF5325) - - - 0.0000000000000000002533 89.0
HKD2_k127_1525806_6 GTP-binding protein TypA K06207 - - 0.0000000003071 61.0
HKD2_k127_1543417_0 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 9.933e-211 663.0
HKD2_k127_1543417_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0005488,GO:0005515,GO:0042802 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 539.0
HKD2_k127_1543417_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000001038 250.0
HKD2_k127_1543417_3 FMN reductase K00299 - 1.5.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000002028 242.0
HKD2_k127_1543417_4 - - - - 0.00000000000000002437 82.0
HKD2_k127_156945_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 466.0
HKD2_k127_156945_1 COG1388 FOG LysM repeat - - - 0.0000000000000000000000000000000000000000825 158.0
HKD2_k127_161796_0 LXG domain of WXG superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 449.0
HKD2_k127_161796_1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 411.0
HKD2_k127_161796_2 Family of unknown function (DUF5383) - - - 0.00000000000000000000000008728 112.0
HKD2_k127_161796_3 RDD family - - - 0.000000000000000000000001126 109.0
HKD2_k127_161796_4 Family of unknown function (DUF5344) - - - 0.0000000000000000000004725 98.0
HKD2_k127_161796_5 Domain of unknown function (DUF5082) - - - 0.0000000000000000000162 95.0
HKD2_k127_1668791_0 - - - - 0.00000000000000000000000005865 110.0
HKD2_k127_1668791_1 - - - - 0.000000000000000000112 89.0
HKD2_k127_1668791_2 - - - - 0.0000000000000001973 80.0
HKD2_k127_1668791_3 - - - - 0.000000000000001078 87.0
HKD2_k127_1668791_4 - - - - 0.0000000000008664 69.0
HKD2_k127_1668791_5 - - - - 0.000000000007843 67.0
HKD2_k127_1677345_0 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 449.0
HKD2_k127_1677345_1 Protein of unknown function (DUF523) - - - 0.000000000000000000000000000000000000000000000000000000000000000001001 230.0
HKD2_k127_1677345_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004418 230.0
HKD2_k127_1677345_3 Stage V sporulation protein AD (SpoVAD) K06406 - - 0.000000000000000000000000000000002917 128.0
HKD2_k127_1677345_4 Protein of unknown function (DUF1657) - - - 0.0000000000000000000000000003737 114.0
HKD2_k127_1677345_5 IDEAL - - - 0.0000000000000000006171 87.0
HKD2_k127_1677345_6 - - - - 0.000000002296 62.0
HKD2_k127_1694817_0 signaling protein consisting of a modified GGDEF domain and a DHH domain - - - 0.0 1090.0
HKD2_k127_1694817_1 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 381.0
HKD2_k127_1694817_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 328.0
HKD2_k127_1694817_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 309.0
HKD2_k127_1694817_4 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001668 258.0
HKD2_k127_1694817_5 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000003112 182.0
HKD2_k127_1694817_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000002572 155.0
HKD2_k127_169514_0 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 388.0
HKD2_k127_169514_1 membrane - - - 0.000000000000000000000000000000000000008317 145.0
HKD2_k127_169514_2 Family of unknown function (DUF5365) - - - 0.0000000000000000000000000000000000001715 145.0
HKD2_k127_169514_3 Phosphoglucomutase K01835 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2 0.000004399 49.0
HKD2_k127_1749274_0 Belongs to the DegT DnrJ EryC1 family K19430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 598.0
HKD2_k127_1749274_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 454.0
HKD2_k127_1749274_2 COG2148 Sugar transferases involved in lipopolysaccharide synthesis K13012,K19428 GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0016740,GO:0016772,GO:0016780,GO:0043170,GO:0044238,GO:0071704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 293.0
HKD2_k127_1749274_3 COG0110 Acetyltransferase (isoleucine patch superfamily) K19429 GO:0003674,GO:0003824,GO:0008374,GO:0016740,GO:0016746,GO:0016747 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002237 255.0
HKD2_k127_1749274_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000001944 166.0
HKD2_k127_1749274_5 Cro/C1-type HTH DNA-binding domain K19449 - - 0.00000000000000000000000000000000000006105 145.0
HKD2_k127_1749274_6 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC K09809 - 2.7.8.12 0.00000009989 53.0
HKD2_k127_1752218_0 nucleoside hydrolase K01239 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 507.0
HKD2_k127_1752218_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 480.0
HKD2_k127_1752218_2 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 348.0
HKD2_k127_1752218_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007446 265.0
HKD2_k127_1752218_4 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00105,K00111 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000003376 243.0
HKD2_k127_1752218_5 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000009993 226.0
HKD2_k127_1752218_6 - - - - 0.0000000000000000000000000000001798 126.0
HKD2_k127_1752218_7 Cold-inducible protein YdjO - - - 0.000000000000000000000000000001071 121.0
HKD2_k127_1752218_8 - - - - 0.000000008464 58.0
HKD2_k127_1760786_0 Belongs to the peptidase S8 family K20486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 417.0
HKD2_k127_1760786_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003884 244.0
HKD2_k127_1760786_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000928 226.0
HKD2_k127_1760786_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000001244 160.0
HKD2_k127_1760786_4 - - - - 0.000000000000000000000000000000000009051 138.0
HKD2_k127_1788938_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - 8.187e-251 781.0
HKD2_k127_1788938_1 4Fe-4S binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 514.0
HKD2_k127_1788938_2 ABC transporter, ATP-binding protein K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 360.0
HKD2_k127_1788938_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 341.0
HKD2_k127_1788938_4 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 337.0
HKD2_k127_1794376_0 Rod shape-determining protein K03569 - - 5.985e-201 628.0
HKD2_k127_1794376_1 flagellar basal body K02392 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 376.0
HKD2_k127_1794376_2 flagellar basal body K02392 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 348.0
HKD2_k127_1794376_3 COG0739 Membrane proteins related to metalloendopeptidases K06386 GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 349.0
HKD2_k127_1794376_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009213 268.0
HKD2_k127_1794376_5 Stage III sporulation protein D K06283 - - 0.00000000000000000000000000000000000000000000000003095 180.0
HKD2_k127_1794376_6 DNA-directed RNA polymerase subunit beta - - - 0.0000000000000000000002689 98.0
HKD2_k127_1794376_7 VanZ like family - - - 0.0000000008426 60.0
HKD2_k127_1794444_0 ATPases associated with a variety of cellular activities K02028,K10038 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 295.0
HKD2_k127_1794444_1 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001196 262.0
HKD2_k127_1794444_2 amino acid transport K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004307 256.0
HKD2_k127_1794444_3 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000842 138.0
HKD2_k127_1794444_4 FCD - - - 0.0000000000000000000000000003699 122.0
HKD2_k127_1794444_5 Single-strand binding protein family - - - 0.00000000002551 68.0
HKD2_k127_1799613_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - 3.227e-253 782.0
HKD2_k127_1799613_1 COG0569 K transport systems, NAD-binding component K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 370.0
HKD2_k127_1799613_2 ISXO2-like transposase domain - - - 0.00000000000001036 74.0
HKD2_k127_1799613_3 ISXO2-like transposase domain - - - 0.0000000006399 61.0
HKD2_k127_1799613_4 thiol-disulfide - - - 0.0000001886 55.0
HKD2_k127_1799613_5 - - - - 0.0000009008 53.0
HKD2_k127_1799791_0 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures K05592,K18692 GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 2.471e-229 715.0
HKD2_k127_1799791_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 2.656e-216 674.0
HKD2_k127_1799791_10 Protein of unknown function (DUF1189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002093 255.0
HKD2_k127_1799791_11 protein conserved in bacteria K09793 - - 0.000000000000000000000000000000000000000000000000000000000000000000004938 237.0
HKD2_k127_1799791_12 YqfQ-like protein - - - 0.0000000000000000000000000000004652 130.0
HKD2_k127_1799791_13 Major facilitator superfamily K08222 - - 0.00000000000000000000000007431 108.0
HKD2_k127_1799791_14 membrane - - - 0.000000000000000000000003213 108.0
HKD2_k127_1799791_15 translation initiation factor activity K08086,K15845 - - 0.0000000000000000000001913 100.0
HKD2_k127_1799791_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 565.0
HKD2_k127_1799791_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 517.0
HKD2_k127_1799791_4 COG1108 ABC-type Mn2 Zn2 transport systems, permease components K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 446.0
HKD2_k127_1799791_5 'COG1121 ABC-type Mn Zn transport systems, ATPase component' K02074,K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 428.0
HKD2_k127_1799791_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 419.0
HKD2_k127_1799791_7 radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 398.0
HKD2_k127_1799791_8 Belongs to the 5'(3')-deoxyribonucleotidase family K05967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009804 292.0
HKD2_k127_1799791_9 Belongs to the Fur family K02076 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000009511 249.0
HKD2_k127_1837446_0 protein conserved in bacteria - - - 8.509e-229 717.0
HKD2_k127_1837446_1 - - - - 0.000000000000000000000000000000000000000001059 160.0
HKD2_k127_1837446_4 - - - - 0.0000003248 52.0
HKD2_k127_1837446_5 DNA/RNA non-specific endonuclease K15051 - - 0.0000006789 51.0
HKD2_k127_1837446_6 - - - - 0.000009252 51.0
HKD2_k127_1837446_7 - - - - 0.00001506 49.0
HKD2_k127_183751_0 chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 337.0
HKD2_k127_183751_1 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000000000000006092 127.0
HKD2_k127_183751_2 - - - - 0.000000000009686 73.0
HKD2_k127_183751_3 RNA catabolic process K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.0000002889 54.0
HKD2_k127_1839910_0 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 5.351e-258 797.0
HKD2_k127_1839910_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 587.0
HKD2_k127_1839910_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 454.0
HKD2_k127_1839910_3 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 305.0
HKD2_k127_1841208_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1157.0
HKD2_k127_1841208_1 COG1796 DNA polymerase IV (family X) K02347 - - 8.257e-312 963.0
HKD2_k127_1841208_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 1.041e-307 949.0
HKD2_k127_1841208_3 membrane protein, required for colicin V production - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008112 282.0
HKD2_k127_1841208_4 membrane K08989 - - 0.0000000000000000000000000000000000000000000000000000000000000000001931 231.0
HKD2_k127_1841208_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000000007038 126.0
HKD2_k127_1841208_6 - - - - 0.00002976 46.0
HKD2_k127_1841208_7 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00005188 48.0
HKD2_k127_1884404_0 Glycosyl transferase family 2 - - - 1.643e-215 673.0
HKD2_k127_1884404_1 glycosyl transferase family - - - 9.934e-212 666.0
HKD2_k127_1884404_2 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000001668 209.0
HKD2_k127_1884404_3 - - - - 0.000000000000000000000000000000000119 135.0
HKD2_k127_194823_0 COG2217 Cation transport ATPase K01534 - 3.6.3.3,3.6.3.5 0.0 1033.0
HKD2_k127_194823_1 Domain of unknown function (DUF4173) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 572.0
HKD2_k127_194823_10 Uncharacterized conserved protein (DUF2164) - - - 0.0000000000000000000000000000007104 123.0
HKD2_k127_194823_11 Belongs to the UPF0435 family - - - 0.000000000000000000000002427 104.0
HKD2_k127_194823_12 - - - - 0.0000002493 52.0
HKD2_k127_194823_2 Rod-share determining protein MreBH K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 534.0
HKD2_k127_194823_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 472.0
HKD2_k127_194823_4 Transition state regulatory protein AbrB K07120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 439.0
HKD2_k127_194823_5 flagellar motor K02556 GO:0001539,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0040011,GO:0044425,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071944,GO:0071973,GO:0071978,GO:0097588 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 409.0
HKD2_k127_194823_6 Belongs to the UPF0761 family K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 381.0
HKD2_k127_194823_7 Flagellar motor protein K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 336.0
HKD2_k127_194823_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 316.0
HKD2_k127_194823_9 Late competence development protein ComFB K02241 - - 0.0000000000000000000000000000000000000000009695 158.0
HKD2_k127_1962064_0 the major facilitator superfamily - - - 6.934e-257 799.0
HKD2_k127_1962064_1 COG1309 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000005225 219.0
HKD2_k127_1962064_2 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000001166 154.0
HKD2_k127_1974793_0 AAA domain - - - 0.0 1154.0
HKD2_k127_1974793_1 Asparagine synthase K01953 - 6.3.5.4 4.876e-318 982.0
HKD2_k127_1974793_10 - - - - 0.0002316 45.0
HKD2_k127_1974793_2 Calcineurin-like phosphoesterase K03547 - - 3.759e-197 621.0
HKD2_k127_1974793_3 Putative RNA methylase family UPF0020 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 370.0
HKD2_k127_1974793_4 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 309.0
HKD2_k127_1974793_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000871 164.0
HKD2_k127_1974793_6 Small, acid-soluble spore proteins, alpha/beta type - - - 0.0000000000000000000000000000000175 128.0
HKD2_k127_1974793_7 - - - - 0.0000000000000000000000000001717 118.0
HKD2_k127_1974793_8 Choloylglycine hydrolase - - - 0.000000000000000000001026 95.0
HKD2_k127_1974793_9 - - - - 0.0000000002981 64.0
HKD2_k127_1982700_0 Belongs to the pyruvate kinase family K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 4.925e-314 969.0
HKD2_k127_1982700_1 Belongs to the malate synthase family K01638 - 2.3.3.9 7.474e-298 918.0
HKD2_k127_1982700_2 Isocitrate lyase K01637 - 4.1.3.1 3.562e-230 717.0
HKD2_k127_1982700_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 572.0
HKD2_k127_1982700_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 520.0
HKD2_k127_1982700_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 497.0
HKD2_k127_1982700_6 sporulation integral membrane protein YtvI - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 478.0
HKD2_k127_1982700_7 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000007238 230.0
HKD2_k127_1982700_8 COG3030 Protein affecting phage T7 exclusion by the F plasmid K07113 - - 0.000000000000000000000000000000000000000000000000001082 186.0
HKD2_k127_1982700_9 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000002686 180.0
HKD2_k127_1984724_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 3.908e-284 874.0
HKD2_k127_1984724_1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381,K00392 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0050311,GO:0055114 1.8.1.2,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 594.0
HKD2_k127_1984724_10 TIGRFAM Nitrilotriacetate monooxygenase component A pristinamycin IIA synthase subunit A K04091 - 1.14.14.5 0.0000000004695 60.0
HKD2_k127_1984724_2 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 501.0
HKD2_k127_1984724_3 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 482.0
HKD2_k127_1984724_4 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 425.0
HKD2_k127_1984724_5 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000007231 168.0
HKD2_k127_1984724_6 riboflavin kinase activity - - - 0.000000000000000000000000000000009115 130.0
HKD2_k127_1984724_7 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - 0.0000000000000000000000000000001013 125.0
HKD2_k127_1984724_9 Uncharacterized small protein (DUF2292) - - - 0.0000000000002679 71.0
HKD2_k127_1986483_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 5.181e-207 650.0
HKD2_k127_1986483_1 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 606.0
HKD2_k127_1986483_10 COG1290 Cytochrome b subunit of the bc complex K03887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 443.0
HKD2_k127_1986483_11 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 381.0
HKD2_k127_1986483_12 Zn-dependent protease K06973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 369.0
HKD2_k127_1986483_13 proteins, LmbE homologs K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 368.0
HKD2_k127_1986483_14 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 327.0
HKD2_k127_1986483_15 sporulation protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 323.0
HKD2_k127_1986483_16 Belongs to the UPF0302 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 316.0
HKD2_k127_1986483_17 Menaquinol-cytochrome c reductase K03886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 299.0
HKD2_k127_1986483_18 methylglyoxal synthase K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.000000000000000000000000000000000000000000000000000000000000000000005991 235.0
HKD2_k127_1986483_19 Nucleotide pyrophosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000002059 189.0
HKD2_k127_1986483_2 N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 600.0
HKD2_k127_1986483_20 Protein of unknown function (DUF2487) - - - 0.0000000000000000000000000000000000000000000000276 173.0
HKD2_k127_1986483_21 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis K06208 GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704 5.4.99.5 0.000000000000000000000000000000000000000000002604 166.0
HKD2_k127_1986483_22 - - - - 0.000000004353 59.0
HKD2_k127_1986483_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 578.0
HKD2_k127_1986483_4 prephenate dehydrogenase K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 526.0
HKD2_k127_1986483_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 501.0
HKD2_k127_1986483_6 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 479.0
HKD2_k127_1986483_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 476.0
HKD2_k127_1986483_8 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 471.0
HKD2_k127_1986483_9 Menaquinol-cytochrome c reductase cytochrome b c subunit K03888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 467.0
HKD2_k127_1989779_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1925.0
HKD2_k127_1989779_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1672.0
HKD2_k127_1989779_10 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 545.0
HKD2_k127_1989779_11 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 533.0
HKD2_k127_1989779_12 cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 492.0
HKD2_k127_1989779_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 487.0
HKD2_k127_1989779_14 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 GO:0000003,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 424.0
HKD2_k127_1989779_15 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 393.0
HKD2_k127_1989779_16 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 386.0
HKD2_k127_1989779_17 stress-induced protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 385.0
HKD2_k127_1989779_18 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 385.0
HKD2_k127_1989779_19 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 369.0
HKD2_k127_1989779_2 COG0474 Cation transport ATPase K01537 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 0.0 1401.0
HKD2_k127_1989779_20 conserved protein, contains S4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 368.0
HKD2_k127_1989779_21 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR K06383 GO:0003674,GO:0003824,GO:0004175,GO:0004190,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0043621,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0070001,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 366.0
HKD2_k127_1989779_22 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 361.0
HKD2_k127_1989779_23 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 351.0
HKD2_k127_1989779_24 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 348.0
HKD2_k127_1989779_25 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 345.0
HKD2_k127_1989779_26 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 340.0
HKD2_k127_1989779_27 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 301.0
HKD2_k127_1989779_28 Cell division initiation protein K04074 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 297.0
HKD2_k127_1989779_29 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 290.0
HKD2_k127_1989779_3 RNA-binding protein homologous to eukaryotic snRNP - - - 5.136e-292 905.0
HKD2_k127_1989779_30 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001111 250.0
HKD2_k127_1989779_31 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000001297 229.0
HKD2_k127_1989779_32 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000008573 213.0
HKD2_k127_1989779_33 sporulation protein - - - 0.000000000000000000000000000000000000000004083 156.0
HKD2_k127_1989779_34 Belongs to the UPF0296 family K09777 - - 0.000000000000000000000000000000000000000006826 154.0
HKD2_k127_1989779_35 membrane K02221 - - 0.0000000000000000000000000000001653 124.0
HKD2_k127_1989779_36 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000008825 108.0
HKD2_k127_1989779_37 - - - - 0.00003364 46.0
HKD2_k127_1989779_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - 1.086e-233 727.0
HKD2_k127_1989779_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 2.008e-231 721.0
HKD2_k127_1989779_6 Belongs to the SEDS family K03588 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 7.971e-219 681.0
HKD2_k127_1989779_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 9.69e-207 647.0
HKD2_k127_1989779_8 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 2.438e-203 638.0
HKD2_k127_1989779_9 Carbamoyl-phosphate synthetase glutamine chain K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 3.542e-200 628.0
HKD2_k127_1998246_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 0.0 1150.0
HKD2_k127_1998246_1 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0 1063.0
HKD2_k127_1998246_10 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000003791 117.0
HKD2_k127_1998246_2 kinase related to dihydroxyacetone kinase K07030 - - 2.234e-284 881.0
HKD2_k127_1998246_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 534.0
HKD2_k127_1998246_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 475.0
HKD2_k127_1998246_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 405.0
HKD2_k127_1998246_6 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 403.0
HKD2_k127_1998246_7 Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 310.0
HKD2_k127_1998246_8 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000984 225.0
HKD2_k127_1998246_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000001471 134.0
HKD2_k127_2016221_0 Asparagine synthase K01953 - 6.3.5.4 0.0 1128.0
HKD2_k127_2016221_1 Protein of unknown function (DUF2777) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 288.0
HKD2_k127_2016221_2 Spore germination protein K06301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002227 249.0
HKD2_k127_2016221_3 UPF0344 protein - - - 0.0000000000000000000000000000000000000000006161 160.0
HKD2_k127_2016221_4 Spore germination protein K06299 GO:0000003,GO:0008150,GO:0009847,GO:0019954,GO:0030436,GO:0032502,GO:0043934 - 0.000000000000000000000000000007044 120.0
HKD2_k127_2016221_5 cell differentiation K06300 - - 0.00000000000000000005934 90.0
HKD2_k127_2016221_6 Spore gernimation protein GerPD K06302 - - 0.00000000003904 65.0
HKD2_k127_2016221_7 - - - - 0.000004127 48.0
HKD2_k127_2016221_8 Spore germination protein GerPE K06303 - - 0.000007298 50.0
HKD2_k127_2029646_0 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 519.0
HKD2_k127_2029646_1 Peptidase S24-like K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 283.0
HKD2_k127_2029646_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000001341 153.0
HKD2_k127_2029646_4 - - - - 0.00000000000000000000000004279 112.0
HKD2_k127_206007_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 476.0
HKD2_k127_206007_1 peptidyl-serine autophosphorylation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 423.0
HKD2_k127_206007_2 HIRAN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 393.0
HKD2_k127_206007_3 S-layer homology domain - - - 0.00000000000000000000000000000000000003987 153.0
HKD2_k127_206007_4 Belongs to the peptidase S8 family - - - 0.000002973 55.0
HKD2_k127_2060816_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 564.0
HKD2_k127_2060816_1 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 341.0
HKD2_k127_2060816_2 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002251 224.0
HKD2_k127_2060816_3 Putative membrane peptidase family (DUF2324) - - - 0.000000000000000000000000000000000000000000000003692 182.0
HKD2_k127_2060816_4 Transcriptional regulator K09681 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000006382 171.0
HKD2_k127_2067370_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 1.169e-264 815.0
HKD2_k127_2067370_1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain K13747 - 4.1.1.96 1.869e-232 721.0
HKD2_k127_2086712_0 Protein of unknown function (DUF3231) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 580.0
HKD2_k127_2086712_1 Lecithin:cholesterol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 568.0
HKD2_k127_2086712_2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 316.0
HKD2_k127_208785_0 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 506.0
HKD2_k127_208785_1 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 316.0
HKD2_k127_208785_2 COG1459 Type II secretory pathway, component PulF K02244 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004677 243.0
HKD2_k127_208785_3 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000009035 162.0
HKD2_k127_208785_4 Protein of unknown function (DUF2626) - - - 0.0000000000000000000000000000000000006662 140.0
HKD2_k127_208785_5 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.00000001711 55.0
HKD2_k127_21155_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 499.0
HKD2_k127_21155_1 - - - - 0.000000000000000000000000000000000000000000000000000000000003848 216.0
HKD2_k127_21155_2 Flavodoxin - - - 0.00000000000000000000000000006684 123.0
HKD2_k127_2129643_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.772e-319 983.0
HKD2_k127_2129643_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 1.92e-248 769.0
HKD2_k127_2129643_2 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 480.0
HKD2_k127_2129643_3 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 454.0
HKD2_k127_2129643_4 Diguanylate cyclase - - - 0.0000000000000000000000000000004147 128.0
HKD2_k127_2129643_6 - - - - 0.00002354 48.0
HKD2_k127_2162476_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 1.086e-264 818.0
HKD2_k127_2162476_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 1.275e-205 649.0
HKD2_k127_2162476_10 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000000000000008052 123.0
HKD2_k127_2162476_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 494.0
HKD2_k127_2162476_3 Belongs to the FPP GGPP synthase family K13789 GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 452.0
HKD2_k127_2162476_4 stage III sporulation protein AG K06396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002832 282.0
HKD2_k127_2162476_5 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005045 253.0
HKD2_k127_2162476_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000000000000185 219.0
HKD2_k127_2162476_7 SpoIIIAH-like protein K06397 - - 0.000000000000000000000000000000000000000000000000000003228 197.0
HKD2_k127_2162476_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000002216 190.0
HKD2_k127_2162476_9 Stage III sporulation protein AF (Spore_III_AF) K06395 - - 0.000000000000000000000000000000000005064 141.0
HKD2_k127_218861_0 Ring hydroxylating alpha subunit (catalytic domain) K03268,K05708,K08689 - 1.14.12.11,1.14.12.18,1.14.12.19,1.14.12.3 3.655e-266 824.0
HKD2_k127_218861_1 Enoyl-(Acyl carrier protein) reductase K08690 - 1.3.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 460.0
HKD2_k127_218861_2 hydrocarbon binding protein (contains V4R domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 439.0
HKD2_k127_218861_3 Ring hydroxylating beta subunit K15750,K16268 - 1.14.12.11,1.14.12.18,1.14.12.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 285.0
HKD2_k127_218861_4 Rieske-like [2Fe-2S] domain K05710 - - 0.00000000000000000000000000000000000000000000001315 173.0
HKD2_k127_218861_5 Bacterial regulatory proteins, tetR family - - - 0.0000000001231 61.0
HKD2_k127_219697_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 387.0
HKD2_k127_219697_1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 318.0
HKD2_k127_219697_2 acetyltransferase K03829 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002667 252.0
HKD2_k127_219697_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000009464 220.0
HKD2_k127_219697_4 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000001988 167.0
HKD2_k127_2221578_0 Nuclease-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 356.0
HKD2_k127_2221578_1 RIO1 family K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 305.0
HKD2_k127_2221578_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 279.0
HKD2_k127_2221578_3 Protein of unknown function (DUF1641) - - - 0.00000000000000000000000003579 109.0
HKD2_k127_2221578_4 - - - - 0.000000000002052 70.0
HKD2_k127_2223980_0 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 3.75e-255 791.0
HKD2_k127_2223980_1 Catalyzes the interconversion of ornithine to glutamate semialdehyde K00819 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009064,GO:0009987,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901605 2.6.1.13 3.929e-217 677.0
HKD2_k127_2223980_10 Family of unknown function (DUF5344) - - - 0.0000000000000005129 80.0
HKD2_k127_2223980_11 - - - - 0.0000009868 53.0
HKD2_k127_2223980_12 - - - - 0.000006097 50.0
HKD2_k127_2223980_2 Aminotransferase K10907 - - 1.119e-207 650.0
HKD2_k127_2223980_3 oxidoreductases, Fe-dependent alcohol dehydrogenase family K19955 - - 1.676e-202 634.0
HKD2_k127_2223980_4 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 430.0
HKD2_k127_2223980_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001 283.0
HKD2_k127_2223980_6 RNA binding protein (contains ribosomal protein S1 domain) K07570,K07571 - - 0.00000000000000000000000000000000000000000000000000000000000001465 217.0
HKD2_k127_2223980_7 nuclease activity K21493 - - 0.00000000000000000000000000000000000000000000000000004186 205.0
HKD2_k127_2223980_8 Domain of unknown function (DUF378) K09779 - - 0.000000000000000000000000000000000008791 137.0
HKD2_k127_2223980_9 Domain of unknown function (DUF5082) - - - 0.000000000000000000003204 97.0
HKD2_k127_2231879_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 8.952e-251 781.0
HKD2_k127_2231879_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 4.03e-243 756.0
HKD2_k127_2231879_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 568.0
HKD2_k127_2231879_3 stage V sporulation protein D K08384 - - 0.000000000000003397 75.0
HKD2_k127_2239958_0 COG0457 FOG TPR repeat - - - 1.688e-260 810.0
HKD2_k127_2239958_1 May be required for sporulation K09762 GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 574.0
HKD2_k127_2239958_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 565.0
HKD2_k127_2239958_3 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 550.0
HKD2_k127_2239958_4 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 496.0
HKD2_k127_2239958_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 355.0
HKD2_k127_2239958_6 Nudix hydrolase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 304.0
HKD2_k127_2239958_7 Phosphocarrier protein Chr K11184 - - 0.00000000000000000000000000000001136 129.0
HKD2_k127_2282179_0 Toxin SpoIISA, type II toxin-antitoxin system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 412.0
HKD2_k127_2282179_1 Cell wall K01449 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 291.0
HKD2_k127_2282179_2 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 290.0
HKD2_k127_2282179_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 285.0
HKD2_k127_2282179_4 Cyclopropane-fatty-acyl-phospholipid synthase - - - 0.000000000000000000000000000000001869 131.0
HKD2_k127_2284933_0 peptidase S66 K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 524.0
HKD2_k127_2284933_1 COG2755 Lysophospholipase L1 and related esterases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 349.0
HKD2_k127_2284933_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 297.0
HKD2_k127_2284933_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000927 258.0
HKD2_k127_2284933_4 peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000003526 255.0
HKD2_k127_2286802_0 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 316.0
HKD2_k127_2286802_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 304.0
HKD2_k127_2286802_2 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 301.0
HKD2_k127_2286802_3 Predicted nucleotidyltransferase K07074 - - 0.000000000000000000000000000000004183 129.0
HKD2_k127_2286802_4 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000002707 123.0
HKD2_k127_2286802_5 - - - - 0.00000000002958 64.0
HKD2_k127_2286802_6 YfhD-like protein - - - 0.000008741 49.0
HKD2_k127_2287068_0 the major facilitator superfamily - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 1.378e-245 767.0
HKD2_k127_2287068_1 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 532.0
HKD2_k127_2287068_2 Domain of unknown function (DUF4395) - - - 0.000000000000000000000000000000000000000000000000000000000000001248 222.0
HKD2_k127_2287068_3 helix_turn_helix multiple antibiotic resistance protein - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000001457 173.0
HKD2_k127_2287068_4 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000000000000000000003427 171.0
HKD2_k127_2291951_0 May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 425.0
HKD2_k127_2291951_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000365 283.0
HKD2_k127_2291951_2 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000001906 259.0
HKD2_k127_2291951_3 - - - - 0.000000000000000000000000000000000000000000000000000002584 194.0
HKD2_k127_2291951_4 - - - - 0.0000000000000000001601 91.0
HKD2_k127_2315495_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K09698 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 1.84e-280 865.0
HKD2_k127_2315495_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 1.153e-258 802.0
HKD2_k127_2315495_10 RNA-binding protein containing a PIN domain K06962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 286.0
HKD2_k127_2315495_11 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 281.0
HKD2_k127_2315495_12 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006719 271.0
HKD2_k127_2315495_13 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) K11145 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000003595 224.0
HKD2_k127_2315495_14 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000001124 107.0
HKD2_k127_2315495_15 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000002523 79.0
HKD2_k127_2315495_16 - - - - 0.0000000005694 61.0
HKD2_k127_2315495_2 COG4956 Integral membrane protein (PIN domain superfamily) - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 557.0
HKD2_k127_2315495_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 440.0
HKD2_k127_2315495_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 424.0
HKD2_k127_2315495_5 Belongs to the sigma-70 factor family K03088,K03091,K12296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 391.0
HKD2_k127_2315495_6 Serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 379.0
HKD2_k127_2315495_7 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 341.0
HKD2_k127_2315495_8 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 332.0
HKD2_k127_2315495_9 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 291.0
HKD2_k127_2335861_0 4 iron, 4 sulfur cluster binding K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 535.0
HKD2_k127_2335861_1 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase K03429 - 2.4.1.315 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009881 269.0
HKD2_k127_2335861_2 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000000000000000000006312 214.0
HKD2_k127_243776_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1398.0
HKD2_k127_243776_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 6.774e-311 962.0
HKD2_k127_243776_10 - - - - 0.0000000000000000000002499 102.0
HKD2_k127_243776_11 Integrase core domain - - - 0.000000000000000001033 87.0
HKD2_k127_243776_13 Belongs to the 'phage' integrase family - - - 0.00000002403 55.0
HKD2_k127_243776_16 CAAX protease self-immunity - - - 0.000004433 51.0
HKD2_k127_243776_17 Transposase - - - 0.00001872 47.0
HKD2_k127_243776_2 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 569.0
HKD2_k127_243776_3 Belongs to the NOS family. Bacterial NOS oxygenase subfamily K00491 GO:0001505,GO:0003674,GO:0003824,GO:0004497,GO:0004517,GO:0006807,GO:0006809,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017144,GO:0034641,GO:0042133,GO:0042136,GO:0044237,GO:0044249,GO:0044271,GO:0046209,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:1903409,GO:2001057 1.14.14.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 549.0
HKD2_k127_243776_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 376.0
HKD2_k127_243776_5 COG2801 Transposase and inactivated derivatives K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000006288 233.0
HKD2_k127_243776_6 ABC transporter, ATP-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000001285 215.0
HKD2_k127_243776_7 transposase activity - - - 0.000000000000000000000000000000000000000000000000000009077 193.0
HKD2_k127_243776_8 Yip1 domain - - - 0.00000000000000000000000000000000000000000000000000009393 194.0
HKD2_k127_243776_9 ABC transporter, ATP-binding protein K02003 - - 0.00000000000000000000000000000403 120.0
HKD2_k127_252147_0 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 447.0
HKD2_k127_252147_2 - - - - 0.00000000000000000000128 99.0
HKD2_k127_2572412_0 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008863 435.0
HKD2_k127_2572412_1 stage V sporulation protein AC K06405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001111 276.0
HKD2_k127_2572412_2 Protein of unknown function (DUF1360) - - - 0.000000000000000000000000000000000000000000006415 165.0
HKD2_k127_2572412_3 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) - - - 0.000000000000000000000000000000000000000154 154.0
HKD2_k127_2572412_4 Spore coat protein Z K06344 - - 0.00000000000000000000000000000000000009987 148.0
HKD2_k127_2572412_5 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP K01090,K01525 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.16,3.6.1.41 0.0000000000000000000002634 99.0
HKD2_k127_25822_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 466.0
HKD2_k127_25822_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 461.0
HKD2_k127_25822_2 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 384.0
HKD2_k127_25822_3 TetR family transcriptional regulator - GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008428 278.0
HKD2_k127_25822_4 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004793 268.0
HKD2_k127_25822_5 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008964 264.0
HKD2_k127_25822_6 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000001446 231.0
HKD2_k127_25822_7 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000005045 218.0
HKD2_k127_25822_8 ABC transporter K02049 - - 0.00000000000000000000003689 99.0
HKD2_k127_2599609_0 P-type ATPase K17686 - 3.6.3.54 0.0 1064.0
HKD2_k127_2599609_1 amino acid - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 4.56e-307 950.0
HKD2_k127_2599609_2 protein conserved in bacteria K21600 - - 0.000000000000000000000000000000000000000000000000006684 182.0
HKD2_k127_2599609_3 Copper resistance protein CopZ K07213 - - 0.0000000000000000000000000000002682 123.0
HKD2_k127_266608_0 Acetolactate synthase K01652,K16787 - 2.2.1.6 3.622e-279 867.0
HKD2_k127_266608_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.732e-277 858.0
HKD2_k127_266608_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 325.0
HKD2_k127_266608_11 Acetolactate synthase K01653,K16785 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005239 267.0
HKD2_k127_266608_12 D-alanyl-D-alanine carboxypeptidase K17733 - - 0.000000000000000000000000000000000000000000000000000004643 193.0
HKD2_k127_266608_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.129e-275 849.0
HKD2_k127_266608_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.214e-250 775.0
HKD2_k127_266608_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 7.129e-232 722.0
HKD2_k127_266608_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 602.0
HKD2_k127_266608_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 585.0
HKD2_k127_266608_7 N-terminal domain of lipoyl synthase of Radical_SAM family K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 501.0
HKD2_k127_266608_8 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 384.0
HKD2_k127_266608_9 Octanoyltransferase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 369.0
HKD2_k127_2671191_0 Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 440.0
HKD2_k127_2671191_1 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 289.0
HKD2_k127_2671191_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000124 75.0
HKD2_k127_2671191_3 Protein of unknown function (DUF3949) - - - 0.0000000009855 60.0
HKD2_k127_272612_0 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 319.0
HKD2_k127_272612_1 WLM domain K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 290.0
HKD2_k127_272612_2 Protein of unknown function (DUF1456) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007168 269.0
HKD2_k127_272612_3 DinB family - - - 0.0000000000000000009219 85.0
HKD2_k127_2765680_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 566.0
HKD2_k127_2765680_1 Histidine kinase K07697 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 535.0
HKD2_k127_2765680_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.0000000000000000000000000000000000000000000000000000000000128 209.0
HKD2_k127_2765680_3 Belongs to the glutaminase family K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000003084 191.0
HKD2_k127_2765680_4 - - - - 0.0004293 44.0
HKD2_k127_2804044_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 536.0
HKD2_k127_2804044_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000004367 213.0
HKD2_k127_2832212_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1208.0
HKD2_k127_2832212_1 Membrane attachment protein K03346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 578.0
HKD2_k127_2832212_2 Primosomal protein DnaI K11144 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 471.0
HKD2_k127_2832212_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 314.0
HKD2_k127_2832212_4 YtxC-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 309.0
HKD2_k127_2832212_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 287.0
HKD2_k127_2832212_6 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 286.0
HKD2_k127_2832212_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000003942 223.0
HKD2_k127_2832212_8 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000007405 114.0
HKD2_k127_2832212_9 Membrane - - - 0.0000000000000000000000004908 107.0
HKD2_k127_2838586_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 3.514e-204 642.0
HKD2_k127_2838586_1 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 611.0
HKD2_k127_2838586_2 stage V sporulation protein K K06413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 519.0
HKD2_k127_2838586_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 497.0
HKD2_k127_2838586_4 COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance - GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 464.0
HKD2_k127_2838586_5 Histidine kinase K07697 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 464.0
HKD2_k127_2838586_6 Protein of unknown function (DUF3189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003555 253.0
HKD2_k127_2838586_7 membrane - - - 0.00000000000000000000000000000000000000000000000000000001008 205.0
HKD2_k127_2838586_8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000133 143.0
HKD2_k127_2838586_9 - - - - 0.000000005438 59.0
HKD2_k127_2842675_0 succinate dehydrogenase K00239 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 1.5e-323 992.0
HKD2_k127_2842675_1 succinate dehydrogenase K00240 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 504.0
HKD2_k127_2842675_2 thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000000000002068 202.0
HKD2_k127_2842675_3 - - - - 0.0000000000000000000000000000000000003658 151.0
HKD2_k127_2842675_4 Beta protein - - - 0.0000000000000000000000000000001845 133.0
HKD2_k127_2842675_5 Transcriptional regulator K01994 - - 0.000000000000000000000008898 100.0
HKD2_k127_288682_0 Ferrous iron transport protein B C terminus K04759 - - 7.48e-288 897.0
HKD2_k127_288682_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 529.0
HKD2_k127_288682_2 transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 341.0
HKD2_k127_288682_3 Putative motility protein - - - 0.00000000000000004315 81.0
HKD2_k127_288682_4 Virus attachment protein p12 family - - - 0.0000000000004708 69.0
HKD2_k127_288682_5 COG1918 Fe2 transport system protein A K04758 - - 0.00001275 47.0
HKD2_k127_289440_0 Protein of unknown function (DUF445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 521.0
HKD2_k127_289440_1 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000000000000000001474 189.0
HKD2_k127_289440_2 - - - - 0.0000000000000000000000000007984 113.0
HKD2_k127_2932265_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1072.0
HKD2_k127_2932265_1 COG0643 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 1.218e-270 848.0
HKD2_k127_2932265_10 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 490.0
HKD2_k127_2932265_11 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 480.0
HKD2_k127_2932265_12 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 475.0
HKD2_k127_2932265_13 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 452.0
HKD2_k127_2932265_14 tyrosine recombinase XerC K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 449.0
HKD2_k127_2932265_15 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor K03706 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 434.0
HKD2_k127_2932265_16 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 426.0
HKD2_k127_2932265_17 flagellar K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 432.0
HKD2_k127_2932265_18 Flagellar Assembly Protein A K09749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 417.0
HKD2_k127_2932265_19 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 397.0
HKD2_k127_2932265_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.341e-255 793.0
HKD2_k127_2932265_20 Flagellar biosynthesis regulator FlhF K02404 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 383.0
HKD2_k127_2932265_21 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 364.0
HKD2_k127_2932265_22 Flagellar biosynthetic protein FliR K02421 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 364.0
HKD2_k127_2932265_23 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 363.0
HKD2_k127_2932265_24 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 313.0
HKD2_k127_2932265_25 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 310.0
HKD2_k127_2932265_26 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 304.0
HKD2_k127_2932265_27 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000003467 241.0
HKD2_k127_2932265_28 Flagellar basal body rod modification protein K02389 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.000000000000000000000000000000000000000000000000000000000000000000007623 239.0
HKD2_k127_2932265_29 Belongs to the flagella basal body rod proteins family K02388 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.0000000000000000000000000000000000000000000000000000000000000000124 226.0
HKD2_k127_2932265_3 COG1157 Flagellar biosynthesis type III secretory pathway ATPase K02412 - 3.6.3.14 2.081e-220 690.0
HKD2_k127_2932265_30 response regulator K03413 - - 0.00000000000000000000000000000000000000000000000000000000000004747 214.0
HKD2_k127_2932265_31 Flagellar hook-length control K02414 GO:0001539,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.0000000000000000000000000000000000000000000000000000000008171 219.0
HKD2_k127_2932265_32 COG0835 Chemotaxis signal transduction protein K03408 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009453,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0042333,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.000000000000000000000000000000000000000000000000000000005886 202.0
HKD2_k127_2932265_33 Flagellar assembly protein FliH K02411 - - 0.00000000000000000000000000000000000000000000000000008325 195.0
HKD2_k127_2932265_34 Flagellar biosynthesis chaperone K02413 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000005736 181.0
HKD2_k127_2932265_35 Flagellar biosynthesis protein, FliO K02418 - - 0.000000000000000000000000000000000000000000000007 179.0
HKD2_k127_2932265_36 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000000000000000000006443 167.0
HKD2_k127_2932265_37 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000005297 158.0
HKD2_k127_2932265_38 Putative flagellar - - - 0.0000000000000000000000000000000000000005352 151.0
HKD2_k127_2932265_39 MgtE intracellular N domain - - - 0.000000000000000000000000000000000003386 145.0
HKD2_k127_2932265_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 3.805e-210 656.0
HKD2_k127_2932265_40 Role in flagellar biosynthesis K02420 - - 0.0000000000000000000000000000000004442 132.0
HKD2_k127_2932265_41 Flagellar hook-basal body K02408 - - 0.0000000000000000000000000002833 116.0
HKD2_k127_2932265_42 protein, possibly involved in motility K02385 - - 0.000000000000000000009335 94.0
HKD2_k127_2932265_43 - - - - 0.0000000000000000005438 91.0
HKD2_k127_2932265_44 - - - - 0.000000000000001215 86.0
HKD2_k127_2932265_45 Cytidylyltransferase family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.00000000000006646 73.0
HKD2_k127_2932265_5 The M ring may be actively involved in energy transduction K02409 - - 1.215e-202 643.0
HKD2_k127_2932265_6 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 601.0
HKD2_k127_2932265_7 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0050918,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 541.0
HKD2_k127_2932265_8 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 493.0
HKD2_k127_2932265_9 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 481.0
HKD2_k127_293353_0 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 390.0
HKD2_k127_293353_1 Belongs to the peptidase S11 family K07258 GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 344.0
HKD2_k127_293353_2 Spore maturation protein K06374 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 287.0
HKD2_k127_293353_3 Spore maturation protein K06373 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003377 251.0
HKD2_k127_293568_0 ATPase. Has a role at an early stage in the morphogenesis of the spore coat K06398 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009653,GO:0009847,GO:0009987,GO:0010927,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022607,GO:0030154,GO:0030203,GO:0030312,GO:0030435,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032989,GO:0034622,GO:0035639,GO:0036094,GO:0042244,GO:0042546,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043170,GO:0043591,GO:0043595,GO:0043933,GO:0043934,GO:0044085,GO:0044426,GO:0044462,GO:0044464,GO:0045229,GO:0048646,GO:0048856,GO:0048869,GO:0051258,GO:0051259,GO:0065003,GO:0070499,GO:0070590,GO:0070726,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 - 4.817e-302 929.0
HKD2_k127_293568_1 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 587.0
HKD2_k127_293568_10 Protein of unknown function (DUF2768) - - - 0.00000000000000000003022 92.0
HKD2_k127_293568_11 - - - - 0.000000803 51.0
HKD2_k127_293568_2 Belongs to the FPP GGPP synthase family K00805,K21275 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 522.0
HKD2_k127_293568_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 390.0
HKD2_k127_293568_4 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 355.0
HKD2_k127_293568_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 311.0
HKD2_k127_293568_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 280.0
HKD2_k127_293568_7 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 K00805 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 286.0
HKD2_k127_293568_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000003814 187.0
HKD2_k127_293568_9 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan K06285 - - 0.0000000000000000000000000000000001599 133.0
HKD2_k127_2938852_0 aminopeptidase K19689 - - 2.792e-221 689.0
HKD2_k127_2938852_1 protein containing a divergent version of the methyl-accepting chemotaxis-like domain - - - 0.00000000000000000000000000000000000000000000000000001792 192.0
HKD2_k127_2938852_2 NosL - - - 0.0000000000000000000000000000000000000000002248 167.0
HKD2_k127_2938852_3 COG4980 Gas vesicle protein - - - 0.000000000000000000000000000000001532 134.0
HKD2_k127_2938852_4 - - - - 0.000001301 50.0
HKD2_k127_29608_0 monooxygenase activity K16242 - - 4.028e-266 825.0
HKD2_k127_29608_1 hydrocarbon binding protein (contains V4R domain) - - - 9.915e-195 625.0
HKD2_k127_29608_2 Methane/Phenol/Toluene Hydroxylase K16243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 535.0
HKD2_k127_29608_3 nitric oxide dioxygenase activity K02823,K18225,K22356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 456.0
HKD2_k127_29608_4 MmoB/DmpM family K16244 - - 0.0000000000000000000000000000002338 125.0
HKD2_k127_2985334_0 transport system, permease component K02069 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 392.0
HKD2_k127_2985334_1 Belongs to the ABC transporter superfamily K02068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 372.0
HKD2_k127_2985334_2 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 337.0
HKD2_k127_2985334_3 Cell wall K01449 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000001591 258.0
HKD2_k127_2985334_4 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006317 247.0
HKD2_k127_2985334_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000002175 200.0
HKD2_k127_2985334_6 EamA-like transporter family - - - 0.0000000000000000399 85.0
HKD2_k127_2985334_7 - - - - 0.00002798 48.0
HKD2_k127_307109_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 363.0
HKD2_k127_307109_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002464 276.0
HKD2_k127_307109_2 Belongs to the binding-protein-dependent transport system permease family K01997,K11960 - - 0.000000000000000000000000000000000000000000000000000000000001656 219.0
HKD2_k127_307109_3 Belongs to the binding-protein-dependent transport system permease family K01998,K11961 - - 0.000000000000000000000000000000000000000000000000000000000001732 222.0
HKD2_k127_307109_4 ABC transporter, ATP-binding protein K01995 - - 0.0000001375 53.0
HKD2_k127_3077357_0 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002181 275.0
HKD2_k127_3077357_1 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000453 117.0
HKD2_k127_3081655_0 Terminase-like family - - - 7.009e-235 734.0
HKD2_k127_3081655_1 - - - - 3.521e-233 736.0
HKD2_k127_3081655_12 - - - - 0.00000000000000005068 83.0
HKD2_k127_3081655_14 domain protein - - - 0.000001923 60.0
HKD2_k127_3081655_15 UDP-N-acetyl-D-mannosamine dehydrogenase activity - - - 0.000007772 53.0
HKD2_k127_3081655_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 557.0
HKD2_k127_3081655_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 359.0
HKD2_k127_3081655_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001824 229.0
HKD2_k127_3081655_5 Protein of unknown function (DUF2829) - - - 0.000000000000000000000000000000000000000003603 156.0
HKD2_k127_3081655_6 - - - - 0.0000000000000000000000000000000000000003399 149.0
HKD2_k127_3081655_7 HNH endonuclease - - - 0.000000000000000000000000000000003254 136.0
HKD2_k127_3081655_8 Homeodomain-like domain - - - 0.0000000000000000000000000000008624 128.0
HKD2_k127_3081655_9 Protein of unknown function (DUF1653) - - - 0.0000000000000000000000000006897 113.0
HKD2_k127_3102149_0 arginine degradation protein - - - 1.771e-303 934.0
HKD2_k127_3134041_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1889.0
HKD2_k127_3134041_1 Methyltransferase K00564 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 338.0
HKD2_k127_3134041_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000000006148 197.0
HKD2_k127_3137483_0 COG0642 Signal transduction histidine kinase - - - 4.045e-198 631.0
HKD2_k127_3137483_1 Acyl--CoA ligase K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 607.0
HKD2_k127_3137483_2 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 400.0
HKD2_k127_3137483_3 Na -dependent transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 388.0
HKD2_k127_3137483_4 DoxX - - - 0.000000000000000000000000000000000000000000000009755 174.0
HKD2_k127_3137483_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000003239 115.0
HKD2_k127_314850_0 Type II secretion system protein E K02243,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 575.0
HKD2_k127_314850_1 Twitching motility protein PilT K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 515.0
HKD2_k127_314850_2 type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 462.0
HKD2_k127_314850_3 Prokaryotic N-terminal methylation motif K02650 - - 0.000000000000000000005437 95.0
HKD2_k127_3154652_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 6.504e-212 664.0
HKD2_k127_3154652_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 447.0
HKD2_k127_3154652_2 protein conserved in bacteria K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 430.0
HKD2_k127_3154652_3 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 394.0
HKD2_k127_3154652_4 - - - - 0.00000000000000000000000000000000000000000000000002789 182.0
HKD2_k127_3154652_5 Protein of unknown function (DUF2653) - - - 0.0000000000000000000000000000000071 129.0
HKD2_k127_3154652_6 Heme biosynthesis protein HemY K13628,K15724 - - 0.000000000000000000000002017 102.0
HKD2_k127_3159755_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 2.144e-228 713.0
HKD2_k127_3159755_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 465.0
HKD2_k127_3159755_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 386.0
HKD2_k127_3159755_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins K03217 GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 387.0
HKD2_k127_3159755_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000000000000000000000000000000007729 163.0
HKD2_k127_3159755_5 Ribosomal protein L34 K02914 - - 0.00000000000000007747 81.0
HKD2_k127_3192899_0 COG1078 HD superfamily phosphohydrolases K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 4.464e-224 696.0
HKD2_k127_3192899_1 In Salmonella this enzyme is required for ethanolamine catabolism K00625,K02028 - 2.3.1.8,3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 507.0
HKD2_k127_3192899_10 Protein of unknown function (DUF1806) - - - 0.0000000000000000000000000000000000000000000000000000001376 196.0
HKD2_k127_3192899_11 small membrane protein - - - 0.0000000000000000000000000000000000000000000000000000024 192.0
HKD2_k127_3192899_12 Belongs to the UPF0741 family - - - 0.00000000000000000000000000000000000005953 142.0
HKD2_k127_3192899_13 Sugar (and other) transporter - - - 0.000000000000000002873 85.0
HKD2_k127_3192899_14 Uracil-DNA glycosylase - - - 0.000000000000000003588 85.0
HKD2_k127_3192899_17 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000003471 57.0
HKD2_k127_3192899_2 May function as heme-dependent peroxidase K00435 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 459.0
HKD2_k127_3192899_3 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes K16869,K18821 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 419.0
HKD2_k127_3192899_4 Transcriptional regulator K19242 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 396.0
HKD2_k127_3192899_5 Transcriptional regulator K06314 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 357.0
HKD2_k127_3192899_6 deacetylase K22135 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 346.0
HKD2_k127_3192899_7 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 331.0
HKD2_k127_3192899_8 O-methyltransferase K15256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 329.0
HKD2_k127_3192899_9 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA K06305 GO:0005575,GO:0005618,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0019538,GO:0030312,GO:0031160,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0071944,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000009571 215.0
HKD2_k127_3192982_0 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001222 241.0
HKD2_k127_3192982_1 GNAT family acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002716 229.0
HKD2_k127_3192982_2 - - - - 0.0000000000000000000000000000000000000000000000000000000001694 224.0
HKD2_k127_3192982_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000001148 195.0
HKD2_k127_3192982_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000001989 193.0
HKD2_k127_3207_0 glutamate synthase K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2498.0
HKD2_k127_3207_1 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 2.431e-280 866.0
HKD2_k127_3207_2 Transcriptional regulator K09681 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 375.0
HKD2_k127_3207_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000004056 168.0
HKD2_k127_3207_4 - - - - 0.000000000000000000000000000002702 123.0
HKD2_k127_3250349_0 H4MPT-linked C1 transfer pathway protein K07072 - 2.5.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000539 247.0
HKD2_k127_3250349_1 Pfam ATP-grasp domain K06914 - 6.3.4.24 0.0000000000000000000000000000000000000000000000000000002492 209.0
HKD2_k127_3250349_2 Protein of unknown function (DUF429) K09147 - - 0.0000000000000000000000000000000000000000000001303 174.0
HKD2_k127_3250349_3 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.0000000000000000000000000000000000000004637 158.0
HKD2_k127_3250349_4 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 GO:0003674,GO:0003824,GO:0004068,GO:0004837,GO:0005488,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019842,GO:0030170,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070279,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001119,GO:2001120 4.1.1.11,4.1.1.25 0.00000000000000000000003762 102.0
HKD2_k127_3250349_5 Putative zinc- or iron-chelating domain K06940 - - 0.00000000007052 70.0
HKD2_k127_3250349_6 Winged helix-turn-helix - - - 0.00003781 51.0
HKD2_k127_3250349_7 Belongs to the eukaryotic ribosomal protein eL38 family K02923 - - 0.0000568 48.0
HKD2_k127_3250349_8 Bacterial PH domain - - - 0.000078 52.0
HKD2_k127_3267836_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 492.0
HKD2_k127_3267836_1 ABC transporter, ATP-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 451.0
HKD2_k127_3267836_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 386.0
HKD2_k127_3267836_3 ABC transporter permease K02004 - - 0.0000000000000000000000000000000000000000000001339 173.0
HKD2_k127_3267836_4 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000001259 159.0
HKD2_k127_328186_0 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane K02761 - - 1.248e-223 699.0
HKD2_k127_328186_1 Mga helix-turn-helix domain K03491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 598.0
HKD2_k127_328186_2 Belongs to the glycosyl hydrolase 1 family K01223 GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 426.0
HKD2_k127_328186_3 transporter subunit IIB K02760 - 2.7.1.196,2.7.1.205 0.0000000000000000000000000000000000000000000000006228 176.0
HKD2_k127_328186_4 phosphotransferase system K02759,K02786 - 2.7.1.196,2.7.1.205,2.7.1.207 0.0000000000000000000000000000000000000000000003007 168.0
HKD2_k127_332933_0 Stage II sporulation protein - GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 426.0
HKD2_k127_332933_1 EcsC protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 401.0
HKD2_k127_332933_2 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000104 186.0
HKD2_k127_332933_3 COG1943 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000001052 180.0
HKD2_k127_332933_4 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases K01081,K08693,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.00000000000000000000000000000000000000000033 174.0
HKD2_k127_332933_5 Belongs to the sigma-70 factor family. ECF subfamily K00960 - 2.7.7.6 0.000000000000000000000000000000000000000009487 159.0
HKD2_k127_332933_6 - - - - 0.00000000000000000000000001076 117.0
HKD2_k127_3394940_0 Belongs to the peptidase S8 family K13274,K20276 - - 0.0 1523.0
HKD2_k127_3394940_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0022804,GO:0022857,GO:0022884,GO:0032940,GO:0033036,GO:0042886,GO:0042887,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:1904680 - 1.267e-310 966.0
HKD2_k127_3422927_0 asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 554.0
HKD2_k127_3422927_1 O-antigen ligase like membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009113 259.0
HKD2_k127_3422927_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000008112 131.0
HKD2_k127_3422927_3 - - - - 0.000000000000000000000003252 105.0
HKD2_k127_3463652_0 IstB-like ATP binding protein K02315,K11144 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 315.0
HKD2_k127_3463652_1 Replication initiation and membrane attachment - - - 0.000000000000000000000000000000000000000000000000000000000000000000001749 243.0
HKD2_k127_3463652_2 - - - - 0.00000000000000000000000001149 112.0
HKD2_k127_3463652_4 - - - - 0.000001903 55.0
HKD2_k127_3463652_6 - - - - 0.0003352 48.0
HKD2_k127_3515817_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 411.0
HKD2_k127_3515817_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 370.0
HKD2_k127_3515817_2 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000254 246.0
HKD2_k127_3515817_3 Putative membrane protein - - - 0.00000000000000000000000000000000007967 136.0
HKD2_k127_3515817_4 - - - - 0.0000000846 56.0
HKD2_k127_354606_0 COG0643 Chemotaxis protein histidine kinase and related kinases - - - 6.593e-219 707.0
HKD2_k127_354606_1 Histidine kinase K07683 - 2.7.13.3 0.00000000000000000000000000000000000000000000001036 190.0
HKD2_k127_354606_2 Two component signalling adaptor domain - - - 0.0000000000000000000000000000000002256 137.0
HKD2_k127_354606_3 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.0000000000000000000000000000001214 136.0
HKD2_k127_354606_4 Membrane-associated sensor domain - - - 0.00000000000000000000000000003156 133.0
HKD2_k127_3658947_0 penicillin-binding protein K05366 GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 0.0 1178.0
HKD2_k127_3658947_1 asparaginyl-tRNA K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 1.951e-253 785.0
HKD2_k127_3658947_11 protein containing a divergent version of the methyl-accepting chemotaxis-like domain - - - 0.000001225 51.0
HKD2_k127_3658947_12 Acyltransferase family - - - 0.0004293 44.0
HKD2_k127_3658947_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 401.0
HKD2_k127_3658947_3 Protein of unknown function (DUF2515) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 382.0
HKD2_k127_3658947_4 DNA replication protein DnaD K02086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 343.0
HKD2_k127_3658947_5 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation K03700 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 313.0
HKD2_k127_3658947_6 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000007632 228.0
HKD2_k127_3658947_7 - - - - 0.000000000000000000000000000000000000000005591 160.0
HKD2_k127_3658947_8 Bacterial domain of unknown function (DUF1798) - - - 0.0000000000000000000000000000000000000005346 152.0
HKD2_k127_3658947_9 YppG-like protein - - - 0.000000000000000000000000000000000000127 148.0
HKD2_k127_3668841_0 Shows a 3'-5' exoribonuclease activity K03698 GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 564.0
HKD2_k127_3668841_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 520.0
HKD2_k127_3668841_10 YhzD-like protein - - - 0.0000000000000000000000002423 105.0
HKD2_k127_3668841_12 - - - - 0.000000004856 58.0
HKD2_k127_3668841_13 Belongs to the UPF0754 family - - - 0.000000147 58.0
HKD2_k127_3668841_2 Extracellular solute-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 512.0
HKD2_k127_3668841_3 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 494.0
HKD2_k127_3668841_4 COG0555 ABC-type sulfate transport system, permease component K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 433.0
HKD2_k127_3668841_5 hydrolases of the HAD superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 427.0
HKD2_k127_3668841_6 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 367.0
HKD2_k127_3668841_7 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 336.0
HKD2_k127_3668841_8 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000002452 188.0
HKD2_k127_3668841_9 Belongs to the UPF0342 family - - - 0.00000000000000000000000000000000000000000000000001068 182.0
HKD2_k127_3691131_0 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 361.0
HKD2_k127_3691131_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005354 259.0
HKD2_k127_3691131_2 Nuclease-related domain - - - 0.0000000000000000000000000001038 117.0
HKD2_k127_3691131_3 Nuclease-related domain - - - 0.000000000000000002672 87.0
HKD2_k127_3698450_0 binding-protein-dependent transport systems inner membrane component K17319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 422.0
HKD2_k127_3698450_1 ABC transporter permease K17320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 394.0
HKD2_k127_3698450_2 ABC transporter substrate-binding protein K17318 - - 0.00000000000000000000000000000000000000000000000000000000003324 214.0
HKD2_k127_3706604_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1239.0
HKD2_k127_3706604_1 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 420.0
HKD2_k127_3706604_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 379.0
HKD2_k127_3706604_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000007956 130.0
HKD2_k127_3707450_0 Fe-S oxidoreductase K04034 - 1.21.98.3 3.727e-304 939.0
HKD2_k127_3707450_1 COG0168 Trk-type K transport systems, membrane components - - - 3.347e-196 620.0
HKD2_k127_3707450_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03093 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 311.0
HKD2_k127_3707450_3 Anti-sigma factor N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000001878 221.0
HKD2_k127_3707450_4 COG3594 Fucose 4-O-acetylase and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000006178 207.0
HKD2_k127_3707450_5 small acid-soluble spore protein K06421 - - 0.00000000000000000000000002043 109.0
HKD2_k127_3707450_6 Domain of unknown function (DUF4430) - - - 0.0000009179 55.0
HKD2_k127_3745222_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 387.0
HKD2_k127_3745222_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000682 157.0
HKD2_k127_3745222_3 Methyltransferase domain - - - 0.000000000000000000000004162 111.0
HKD2_k127_3745222_4 Protein of unknown function DUF86 - - - 0.0000000000000004758 79.0
HKD2_k127_3793236_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1386.0
HKD2_k127_3793236_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 575.0
HKD2_k127_3793236_2 COG0515 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 429.0
HKD2_k127_3793236_3 membrane protein domain - - - 0.000000000000000000000000000000000000006176 152.0
HKD2_k127_3796178_0 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 515.0
HKD2_k127_3796415_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 9.668e-221 689.0
HKD2_k127_3796415_1 hydrolase, TatD K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 424.0
HKD2_k127_3855452_0 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 560.0
HKD2_k127_3855452_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 357.0
HKD2_k127_3855452_2 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000002301 222.0
HKD2_k127_3855452_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000003355 187.0
HKD2_k127_3855452_4 polyhydroxyalkanoic acid inclusion protein PhaP - - - 0.0000000000000000000000000000000000000003575 154.0
HKD2_k127_3855452_5 polyhydroxyalkanoic acid synthase, PhaR subunit - - - 0.000000000000000000000000000000001165 135.0
HKD2_k127_3878324_0 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 513.0
HKD2_k127_3878324_1 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system K09693 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0015921,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1901264,GO:1901505 3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 437.0
HKD2_k127_3878324_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 439.0
HKD2_k127_3878324_3 Transport permease protein K09692 GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0033036,GO:0051179,GO:0051234,GO:0071702,GO:1901264 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 407.0
HKD2_k127_3878324_4 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC K09809 - 2.7.8.12 0.00000005622 55.0
HKD2_k127_3925540_0 Cell division protein FtsA - - - 5.941e-283 886.0
HKD2_k127_3925540_1 histone deacetylase K04768 - - 2.022e-208 652.0
HKD2_k127_3925540_2 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate K03856,K13853 - 2.5.1.54,5.4.99.5 2.112e-199 624.0
HKD2_k127_3925540_3 catabolite control protein A K02529 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 540.0
HKD2_k127_3925540_4 - - - - 0.000001612 50.0
HKD2_k127_3925540_5 - - - - 0.000003583 49.0
HKD2_k127_3947034_0 5TMR of 5TMR-LYT K07697 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 523.0
HKD2_k127_3947034_1 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000002375 211.0
HKD2_k127_3947034_2 Staygreen protein - - - 0.000000000000000000000000000000000000000000000000000000000003798 211.0
HKD2_k127_4000241_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0 1260.0
HKD2_k127_4000241_1 ABC transporter K06158 - - 0.0 1060.0
HKD2_k127_4000241_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000000003553 183.0
HKD2_k127_4000241_11 Domain of unknown function (DUF4305) - - - 0.000000000000000000000000003533 111.0
HKD2_k127_4000241_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - 3.356e-319 980.0
HKD2_k127_4000241_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 5.209e-310 952.0
HKD2_k127_4000241_4 COG1305 Transglutaminase-like enzymes - - - 2.286e-203 656.0
HKD2_k127_4000241_5 COG0714 MoxR-like ATPases K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 501.0
HKD2_k127_4000241_6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 362.0
HKD2_k127_4000241_7 metal-dependent membrane protease K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 287.0
HKD2_k127_4000241_8 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007083 286.0
HKD2_k127_4000241_9 chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002284 251.0
HKD2_k127_400795_0 cation transport ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 538.0
HKD2_k127_400795_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 385.0
HKD2_k127_400795_2 Acyl-CoA hydrolase K01073 - 3.1.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000219 260.0
HKD2_k127_4155653_0 Penicillin-binding Protein K08724,K12552,K12556 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.572e-248 775.0
HKD2_k127_4155653_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 509.0
HKD2_k127_4155653_2 Essential cell division protein - - - 0.00000000000000000000000000000000000002353 146.0
HKD2_k127_4155653_3 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000003637 134.0
HKD2_k127_4156237_0 - - - - 0.0000000002549 66.0
HKD2_k127_4156237_1 Evidence 4 Homologs of previously reported genes of - - - 0.000001616 60.0
HKD2_k127_4156237_2 Evidence 4 Homologs of previously reported genes of - - - 0.000005121 58.0
HKD2_k127_4162792_0 ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - 0.0 1203.0
HKD2_k127_4162792_1 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 297.0
HKD2_k127_4162792_2 Thioredoxin - GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000000000000000007452 181.0
HKD2_k127_4162792_3 - - - - 0.000000000000000000000000000000000000000000000298 175.0
HKD2_k127_4166528_0 HAD-hyrolase-like K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 468.0
HKD2_k127_4166528_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 362.0
HKD2_k127_4166528_2 B3/4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 314.0
HKD2_k127_4166528_3 - - - - 0.00000001079 58.0
HKD2_k127_4166528_4 - - - - 0.000000308 53.0
HKD2_k127_4179353_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 553.0
HKD2_k127_4179353_1 isocitrate K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 442.0
HKD2_k127_4179353_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 430.0
HKD2_k127_4179353_3 Single Cache-like K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 316.0
HKD2_k127_4189759_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 594.0
HKD2_k127_4189759_1 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 400.0
HKD2_k127_4189759_2 COG1214 Inactive homolog of metal-dependent proteases K01409,K14742 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 377.0
HKD2_k127_4189759_3 ATPase or kinase K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000001974 240.0
HKD2_k127_4189759_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000000003779 147.0
HKD2_k127_41969_0 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 601.0
HKD2_k127_41969_1 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 300.0
HKD2_k127_41969_2 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006334 257.0
HKD2_k127_41969_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004422 254.0
HKD2_k127_41969_4 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000008023 236.0
HKD2_k127_41969_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000004966 232.0
HKD2_k127_41969_6 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000003474 218.0
HKD2_k127_41969_7 - - - - 0.00000000000000000000000000000000001621 136.0
HKD2_k127_41969_8 - - - - 0.000000000000000000000000006341 111.0
HKD2_k127_4222646_0 Aminotransferase K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 604.0
HKD2_k127_4222646_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 547.0
HKD2_k127_4222646_2 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 506.0
HKD2_k127_4222646_3 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 390.0
HKD2_k127_4222646_4 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000000000000002471 183.0
HKD2_k127_4230298_0 Orn Lys Arg decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 598.0
HKD2_k127_4230298_1 stage 0 sporulation protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 531.0
HKD2_k127_4230298_2 DNA polymerase III K02341 GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007009 523.0
HKD2_k127_4230298_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 509.0
HKD2_k127_4230298_4 Conserved hypothetical protein 95 K07461,K15460 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 441.0
HKD2_k127_4230298_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 310.0
HKD2_k127_4230298_6 Involved in initiation control of chromosome replication - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000004171 181.0
HKD2_k127_4230298_7 COG2002 Regulators of stationary sporulation gene expression K06284 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0042802,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - 0.000000000000000000000000000000000000000000002569 165.0
HKD2_k127_4230298_8 endonuclease containing a URI domain K07461 - - 0.00000000000000000000000005126 110.0
HKD2_k127_4230298_9 Inhibitor of sigma-G Gin - - - 0.000000000000000000000004482 101.0
HKD2_k127_4253306_0 TIGR00255 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 460.0
HKD2_k127_4253306_1 - - - - 0.0000000000000000000000000009858 114.0
HKD2_k127_4253306_2 Belongs to the UPF0296 family K09777 - - 0.00000000000000000000002448 99.0
HKD2_k127_4254259_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 7.894e-289 904.0
HKD2_k127_4254259_1 the major facilitator superfamily - - - 3.217e-215 678.0
HKD2_k127_4254259_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 431.0
HKD2_k127_4254259_3 COG0477 Permeases of the major facilitator superfamily K08224 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 430.0
HKD2_k127_4254259_4 COG1309 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 323.0
HKD2_k127_4254259_5 COG0322 Nuclease subunit of the excinuclease complex - GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000005584 207.0
HKD2_k127_4254259_6 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000006443 164.0
HKD2_k127_4254259_7 - - - - 0.000005492 49.0
HKD2_k127_4255577_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 3.23e-252 794.0
HKD2_k127_4255577_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 4.778e-251 780.0
HKD2_k127_4255577_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 6.372e-211 659.0
HKD2_k127_4255577_3 Glucose-1-phosphate adenylyltransferase, GlgD subunit K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 578.0
HKD2_k127_4255577_4 Glycosyl hydrolases family 15 K07190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 558.0
HKD2_k127_4255577_5 exodeoxyribonuclease III K01142 GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 425.0
HKD2_k127_4255577_6 Belongs to the glycosyl hydrolase 13 family K01200 - 3.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000719 240.0
HKD2_k127_4255577_7 - - - - 0.0000000000000000000000000000000000000000000000000000000001953 205.0
HKD2_k127_4256708_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380 - 1.8.1.2 5.534e-313 968.0
HKD2_k127_4256708_1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381,K00392 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0050311,GO:0055114 1.8.1.2,1.8.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 565.0
HKD2_k127_4256708_2 Transcriptional regulator K21900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 515.0
HKD2_k127_4256708_3 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 382.0
HKD2_k127_4256708_4 metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 364.0
HKD2_k127_4256708_5 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 322.0
HKD2_k127_4256708_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000001339 220.0
HKD2_k127_4256708_7 protein conserved in bacteria - - - 0.000000000000000001822 85.0
HKD2_k127_4256708_8 - - - - 0.000005206 49.0
HKD2_k127_4257335_0 Alpha amylase, N-terminal ig-like domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 1.701e-277 863.0
HKD2_k127_4257335_1 Alpha amylase, catalytic domain K01176 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 571.0
HKD2_k127_4257335_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 402.0
HKD2_k127_4257335_3 - - - - 0.000004933 49.0
HKD2_k127_4266325_0 Histidine kinase K07697 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 526.0
HKD2_k127_4266325_1 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000001465 214.0
HKD2_k127_4390281_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1174.0
HKD2_k127_4390281_1 Copper amine oxidase, enzyme domain K00276 - 1.4.3.21 9.309e-202 633.0
HKD2_k127_4390281_2 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000002012 235.0
HKD2_k127_440273_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 5.539e-221 694.0
HKD2_k127_440273_1 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 559.0
HKD2_k127_440273_2 Arginine K01581,K01585 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.17,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 492.0
HKD2_k127_440273_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 486.0
HKD2_k127_440273_4 Anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 317.0
HKD2_k127_440273_5 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001034 269.0
HKD2_k127_440273_6 Belongs to the UPF0223 family - - - 0.000000000000000000000000000000000002673 138.0
HKD2_k127_440273_7 - - - - 0.0000007482 53.0
HKD2_k127_4429781_0 Zn_pept K01308 - 3.4.19.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 473.0
HKD2_k127_4429781_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 456.0
HKD2_k127_4429781_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 340.0
HKD2_k127_4429781_3 - - - - 0.000000000000000000000000000000000000000000000000000006562 192.0
HKD2_k127_4429781_4 COG1388 FOG LysM repeat K19223,K19224 - - 0.00000000000000000000000000000000000000000000188 166.0
HKD2_k127_4429781_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0022804,GO:0022857,GO:0022884,GO:0032940,GO:0033036,GO:0042886,GO:0042887,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:1904680 - 0.0000000000000000000006735 97.0
HKD2_k127_4429781_6 - - - - 0.0000001675 57.0
HKD2_k127_4445551_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.4.1.2,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 554.0
HKD2_k127_4445551_1 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC K16511 GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006697 276.0
HKD2_k127_4445551_2 Protein of unknown function (DUF2663) - - - 0.00000000000000000000000000000000000000000000000000000000000008595 216.0
HKD2_k127_4461286_0 reductase K21567 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 567.0
HKD2_k127_4461286_1 Uncharacterized protein conserved in bacteria (DUF2225) K09766 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 286.0
HKD2_k127_4461286_2 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000000000001074 205.0
HKD2_k127_4461286_3 NADH dehydrogenase K03885 GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 0.0000000000000000000000000000002629 123.0
HKD2_k127_447225_0 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 319.0
HKD2_k127_447225_1 Transketolase, pyrimidine binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 305.0
HKD2_k127_4492144_0 Sugar isomerase, AgaS family K02082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 360.0
HKD2_k127_4492144_1 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005308 276.0
HKD2_k127_4492144_2 Protein phosphatase 2C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 260.0
HKD2_k127_452958_0 Belongs to the FtsK SpoIIIE SftA family K03466 GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0 1152.0
HKD2_k127_452958_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - 6.563e-293 905.0
HKD2_k127_452958_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 300.0
HKD2_k127_452958_11 Protein of unknown function (DUF3243) - - - 0.0000000000000000000000000000000000000001466 151.0
HKD2_k127_452958_12 - - - - 0.00000000000000000000000000000005729 126.0
HKD2_k127_452958_14 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000372 50.0
HKD2_k127_452958_2 zinc protease - - - 2.532e-222 694.0
HKD2_k127_452958_3 Belongs to the CinA family K03742,K03743 - 3.5.1.42 1.878e-204 642.0
HKD2_k127_452958_4 Peptidase M16 - - - 3.104e-197 623.0
HKD2_k127_452958_5 Protein of unknown function (DUF3388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 470.0
HKD2_k127_452958_6 ABC-type transport system, periplasmic component surface lipoprotein K02058,K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 472.0
HKD2_k127_452958_7 COG0740 Protease subunit of ATP-dependent Clp proteases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 418.0
HKD2_k127_452958_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 412.0
HKD2_k127_452958_9 protein conserved in bacteria K15539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 345.0
HKD2_k127_453431_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 409.0
HKD2_k127_453431_1 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005805 249.0
HKD2_k127_453431_2 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001754 234.0
HKD2_k127_453431_3 - - - - 0.00000000000000000000000001007 115.0
HKD2_k127_45674_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 449.0
HKD2_k127_45674_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 418.0
HKD2_k127_45674_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000002506 222.0
HKD2_k127_4569577_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2494.0
HKD2_k127_4569577_1 ABC transporter K11085 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 2.775e-297 919.0
HKD2_k127_4569577_2 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 3.058e-249 772.0
HKD2_k127_4569577_3 transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 591.0
HKD2_k127_4569577_4 ABC transporter (permease) K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 433.0
HKD2_k127_4569577_5 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 422.0
HKD2_k127_4569577_6 Belongs to the UPF0374 family K07586 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 337.0
HKD2_k127_4569577_7 YgaB-like protein - - - 0.0000000000000000000396 92.0
HKD2_k127_4577578_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1541.0
HKD2_k127_4588920_0 stress-induced protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 404.0
HKD2_k127_4588920_1 COG0474 Cation transport ATPase K01537 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000124 202.0
HKD2_k127_4588920_2 Belongs to the UPF0296 family K09777 - - 0.00000000000000000000004349 98.0
HKD2_k127_4601333_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 394.0
HKD2_k127_4601333_1 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000008409 258.0
HKD2_k127_4601333_2 Putative adhesin - - - 0.00000000006933 63.0
HKD2_k127_4601871_0 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 1.271e-282 873.0
HKD2_k127_4601871_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.443e-256 797.0
HKD2_k127_4601871_10 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000002184 208.0
HKD2_k127_4601871_11 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000001208 187.0
HKD2_k127_4601871_12 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure K11686 - - 0.00000000000000000000000000000000000000000000007439 174.0
HKD2_k127_4601871_13 Biotin carboxyl carrier protein K02160 - - 0.00000000000000000000002529 100.0
HKD2_k127_4601871_14 Domain of unknown function (DUF4190) - - - 0.000000000000000000001536 96.0
HKD2_k127_4601871_16 - - - - 0.00000006764 59.0
HKD2_k127_4601871_2 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 7.768e-231 721.0
HKD2_k127_4601871_3 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 497.0
HKD2_k127_4601871_4 Hydroxymethylglutaryl-CoA lyase K01640 GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006579 438.0
HKD2_k127_4601871_5 Belongs to the enoyl-CoA hydratase isomerase family - GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 430.0
HKD2_k127_4601871_6 Squalene/phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 424.0
HKD2_k127_4601871_7 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 368.0
HKD2_k127_4601871_8 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 366.0
HKD2_k127_4601871_9 AMP-binding enzyme K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 303.0
HKD2_k127_4640576_0 Belongs to the peptidase S8 family K13274,K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 526.0
HKD2_k127_4640576_1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K01227 - 3.2.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 312.0
HKD2_k127_4640576_2 COG1388 FOG LysM repeat K19223,K19224 - - 0.00000000000000000000000000000000000000005595 160.0
HKD2_k127_4653011_0 COG1387 Histidinol phosphatase and related hydrolases of the PHP family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 442.0
HKD2_k127_4653011_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 427.0
HKD2_k127_4653011_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 363.0
HKD2_k127_4653011_3 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 361.0
HKD2_k127_4653011_4 DeoR C terminal sensor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001892 273.0
HKD2_k127_4653011_5 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000009885 239.0
HKD2_k127_466769_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 501.0
HKD2_k127_466769_1 Arginine K01581,K01585 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.17,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 349.0
HKD2_k127_466769_2 - - - - 0.000000000000001155 79.0
HKD2_k127_466769_3 SR1 protein - - - 0.00000004475 55.0
HKD2_k127_4668839_0 COG0744 Membrane carboxypeptidase (penicillin-binding protein) K03693,K12551 - 2.4.1.129 0.0 1137.0
HKD2_k127_4668839_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 1.957e-250 775.0
HKD2_k127_4668839_2 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization K06286 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 5.699e-236 741.0
HKD2_k127_4668839_3 COG2199 FOG GGDEF domain - - - 5.145e-209 666.0
HKD2_k127_4668839_4 Cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 571.0
HKD2_k127_4668839_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 433.0
HKD2_k127_4668839_6 COG1387 Histidinol phosphatase and related hydrolases of the PHP family K04486 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 425.0
HKD2_k127_4668839_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 370.0
HKD2_k127_4668839_8 Transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 331.0
HKD2_k127_4668839_9 GAF domain-containing protein K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000000000000000000000000000002638 246.0
HKD2_k127_4669186_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1058.0
HKD2_k127_4669186_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 7.008e-261 807.0
HKD2_k127_4669186_2 protein conserved in bacteria - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 477.0
HKD2_k127_4669186_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 371.0
HKD2_k127_4671970_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 1.508e-246 764.0
HKD2_k127_4671970_1 transcriptional K03892,K22043 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000003278 205.0
HKD2_k127_4671970_2 chemotaxis protein K03406 - - 0.00000000000000000000000000002156 128.0
HKD2_k127_4681758_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.526e-307 945.0
HKD2_k127_4681758_1 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000001124 221.0
HKD2_k127_4681758_2 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling K03048 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000001201 174.0
HKD2_k127_4681758_3 - - - - 0.00003745 46.0
HKD2_k127_4702655_0 Tetrapyrrole (Corrin/Porphyrin) Methylases K21479 - 2.1.1.272 2.689e-303 936.0
HKD2_k127_4702655_1 CbiX K03795 - 4.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 520.0
HKD2_k127_4702655_2 ATPases associated with a variety of cellular activities K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 426.0
HKD2_k127_4702655_3 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 409.0
HKD2_k127_4702655_4 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 321.0
HKD2_k127_4702655_5 Cobalamin biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000004814 187.0
HKD2_k127_4702655_6 Cobalt transport protein component CbiN K02009 - - 0.00000000000000000000000000000000000002465 146.0
HKD2_k127_4702655_7 Precorrin-6x reductase CbiJ/CobK K05895 - 1.3.1.106,1.3.1.54 0.00000000000000000362 84.0
HKD2_k127_4761467_0 Belongs to the thiolase family K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 6.375e-205 642.0
HKD2_k127_4761467_1 Transcriptional regulator - - - 0.00000000000000000000000000006163 117.0
HKD2_k127_4761467_2 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.0000000000000000000000000003218 114.0
HKD2_k127_4762552_0 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 475.0
HKD2_k127_4762552_1 3-mercaptopyruvate sulfurtransferase K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 363.0
HKD2_k127_4762552_10 Transcriptional regulator C-terminal region - - - 0.000000000000000007193 83.0
HKD2_k127_4762552_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 308.0
HKD2_k127_4762552_3 Transcriptional regulator C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 302.0
HKD2_k127_4762552_4 Transcriptional regulator C-terminal region - - - 0.0000000000000000000000000000000000000000000005122 168.0
HKD2_k127_4762552_5 - - - - 0.0000000000000000000000000000000000000000000009395 167.0
HKD2_k127_4762552_6 - - - - 0.000000000000000000000000000000000000000002366 159.0
HKD2_k127_4762552_7 Nuclease-related domain - - - 0.0000000000000000000000000000000000009554 142.0
HKD2_k127_4762552_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K19548 - 1.1.1.385 0.000000000000000000000000000000000002845 137.0
HKD2_k127_4762552_9 - - - - 0.0000000000000000000000000003556 114.0
HKD2_k127_4768372_0 COG5401 Spore germination protein K06298 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 411.0
HKD2_k127_4768372_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 321.0
HKD2_k127_4768372_2 Phosphoesterase K07095 GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000005805 249.0
HKD2_k127_4768372_3 domain protein - - - 0.0000000000000000000000000000000000006058 149.0
HKD2_k127_4768372_4 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000000000000000001368 135.0
HKD2_k127_4768372_5 D-alanyl-D-alanine carboxypeptidase K17733 - - 0.0000000000000000000002008 99.0
HKD2_k127_4768372_6 - - - - 0.00000001711 55.0
HKD2_k127_4779198_0 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005579 245.0
HKD2_k127_4779198_1 Stage V sporulation protein R K06415 - - 0.00000000000000000000000000000000000000000000000000000000000000007806 222.0
HKD2_k127_4779198_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000001593 203.0
HKD2_k127_4779198_3 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000008779 168.0
HKD2_k127_4779198_4 Rhodanese domain protein - - - 0.00000000000000000001436 92.0
HKD2_k127_4779198_5 Rhodanese Homology Domain - - - 0.00000000217 58.0
HKD2_k127_4779198_6 - - - - 0.00000008713 57.0
HKD2_k127_4779198_8 protein maturation K07400,K13628 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 - 0.0002758 45.0
HKD2_k127_4831220_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 495.0
HKD2_k127_4831220_1 stage II sporulation protein R K06387 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 300.0
HKD2_k127_4831220_2 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005711 264.0
HKD2_k127_4831220_3 - - - - 0.000000004609 59.0
HKD2_k127_483514_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 2.606e-245 762.0
HKD2_k127_483514_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 1.889e-226 705.0
HKD2_k127_483514_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 452.0
HKD2_k127_483514_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 376.0
HKD2_k127_4836150_0 Belongs to the IlvD Edd family K01687,K16786 - 4.2.1.9 0.0 1075.0
HKD2_k127_4836150_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 1.319e-293 912.0
HKD2_k127_4836150_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00651 GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750 2.3.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 514.0
HKD2_k127_4836150_3 Putative SAM-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 340.0
HKD2_k127_4836150_4 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004733 277.0
HKD2_k127_4836150_5 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002875 268.0
HKD2_k127_4836150_6 Belongs to the UPF0403 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002542 238.0
HKD2_k127_4836150_7 - - - - 0.00000000000000000000000000000000000000000000000000001723 194.0
HKD2_k127_4836150_8 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03169 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000005335 185.0
HKD2_k127_483800_0 transporter ATPase K01551 - 3.6.3.16 4.358e-230 727.0
HKD2_k127_483800_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 359.0
HKD2_k127_483800_2 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000131 218.0
HKD2_k127_483800_3 Fe-S cluster assembly protein HesB - - - 0.000000000000000000000000003539 113.0
HKD2_k127_483800_4 Arsenic resistance operon repressor - - - 0.00000001026 57.0
HKD2_k127_4850669_0 Spore germination protein K06295,K06307 - - 2.039e-257 802.0
HKD2_k127_4850669_1 Conserved region in glutamate synthase - - - 1.012e-239 747.0
HKD2_k127_4850669_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K10620 - 1.3.1.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 418.0
HKD2_k127_4850669_11 Uncharacterized conserved protein (COG2071) K09166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 386.0
HKD2_k127_4850669_12 Spore germination protein K06296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 348.0
HKD2_k127_4850669_13 Spore germination B3/ GerAC like, C-terminal K06297 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 332.0
HKD2_k127_4850669_14 COG0346 Lactoylglutathione lyase and related lyases K10621 - 1.13.11.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 315.0
HKD2_k127_4850669_15 Acyl-CoA dehydrogenase, N-terminal domain K04117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 306.0
HKD2_k127_4850669_16 Conserved region in glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000496 269.0
HKD2_k127_4850669_17 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor K16303 - 1.14.12.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001435 259.0
HKD2_k127_4850669_18 Spore germination protein K06296 - - 0.00000000000000000000000000000000000000000000000000000000000008399 218.0
HKD2_k127_4850669_19 dehydratase - - - 0.00000000000000000000000000000000000000000000000000006057 190.0
HKD2_k127_4850669_2 Spore germination protein K06295,K06307 - - 5.506e-205 649.0
HKD2_k127_4850669_20 Domain of unknown function (DUF3870) - - - 0.000000000000000000000000000000000000000000000006888 173.0
HKD2_k127_4850669_21 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000001088 179.0
HKD2_k127_4850669_22 - - - - 0.000000000000000001425 88.0
HKD2_k127_4850669_23 - - - - 0.000000004202 59.0
HKD2_k127_4850669_24 - - - - 0.0000000976 57.0
HKD2_k127_4850669_3 acyl-CoA transferases carnitine dehydratase K18702 - 2.8.3.19 1.569e-204 642.0
HKD2_k127_4850669_4 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K10619 - 1.14.12.25 8.391e-201 632.0
HKD2_k127_4850669_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 559.0
HKD2_k127_4850669_6 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 543.0
HKD2_k127_4850669_7 Spore germination protein K06296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 509.0
HKD2_k127_4850669_8 Spore germination protein K06296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 501.0
HKD2_k127_4850669_9 Spore germination B3/ GerAC like, C-terminal K06297 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 475.0
HKD2_k127_48569_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 5.48e-237 738.0
HKD2_k127_48569_1 cytochrome C K02497 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 445.0
HKD2_k127_48569_2 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 350.0
HKD2_k127_48569_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000001129 229.0
HKD2_k127_48569_4 - - - - 0.000000000000000000000000000000000000000000000000000000000008918 210.0
HKD2_k127_48569_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000005728 86.0
HKD2_k127_4865692_0 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 406.0
HKD2_k127_4865692_1 binding-protein-dependent transport systems inner membrane component K15599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 383.0
HKD2_k127_4865692_2 ABC transporter, ATP-binding protein K02049,K15600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 327.0
HKD2_k127_4865692_3 domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003462 263.0
HKD2_k127_4865692_4 COG2940 Proteins containing SET domain K07117 - - 0.000000000000000000000000000000000000000000000000000000000000000000004511 235.0
HKD2_k127_4865692_5 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000005317 228.0
HKD2_k127_4865692_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051,K15598 - - 0.000000000000000000000000000000000000000000000000000000000000000006707 229.0
HKD2_k127_4896636_0 Aminotransferase class-V - - - 1.029e-213 665.0
HKD2_k127_4896636_1 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000000000000000000000000000000000000000000000000000000005818 218.0
HKD2_k127_4896636_2 NosL K19342 - - 0.000000000000000000000000001165 124.0
HKD2_k127_494638_0 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane K02761 - - 5.598e-220 688.0
HKD2_k127_494638_1 Belongs to the glycosyl hydrolase 1 family K01223 GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001144 272.0
HKD2_k127_494638_2 phosphotransferase system K02759,K02786 - 2.7.1.196,2.7.1.205,2.7.1.207 0.000000000000000000000000000000000000000000002856 166.0
HKD2_k127_494638_3 transporter subunit IIB K02760 - 2.7.1.196,2.7.1.205 0.0000000000000000000000000000000000000008453 148.0
HKD2_k127_4953669_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 5.515e-257 800.0
HKD2_k127_4953669_1 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 5.636e-242 756.0
HKD2_k127_4953669_11 Protein of unknown function (DUF1659) - - - 0.0000000004347 63.0
HKD2_k127_4953669_12 - - - - 0.00000002966 57.0
HKD2_k127_4953669_13 - - - - 0.00003602 48.0
HKD2_k127_4953669_2 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 526.0
HKD2_k127_4953669_3 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 497.0
HKD2_k127_4953669_4 ABC transporter, ATP-binding protein K01990,K16921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 443.0
HKD2_k127_4953669_5 COG0861 Membrane protein TerC, possibly involved in tellurium resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 395.0
HKD2_k127_4953669_6 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 343.0
HKD2_k127_4953669_7 Transcriptional regulator K07979 - - 0.000000000000000000000000000000000000000000001277 168.0
HKD2_k127_4953669_8 Cold-shock protein K03704 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000256 131.0
HKD2_k127_4953669_9 Protein of unknown function (DUF2922) - - - 0.000000000000000000003498 94.0
HKD2_k127_4987172_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 5.633e-247 766.0
HKD2_k127_4987172_1 Aldolase K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 503.0
HKD2_k127_4987172_2 fructose-1,6-bisphosphatase K02446 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 417.0
HKD2_k127_4987172_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 373.0
HKD2_k127_4987172_4 COG0784 FOG CheY-like receiver K02490 - - 0.000000000000000000000000000000000000000000000000000000000000000003422 227.0
HKD2_k127_4987172_5 Domain of unknown function (DUF2529) - - - 0.0000000000000000000000000000000000000000000000000000000009231 205.0
HKD2_k127_5033163_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0 1079.0
HKD2_k127_5033163_1 Electron transfer flavoprotein K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 571.0
HKD2_k127_5033163_2 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009985 464.0
HKD2_k127_5033163_3 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D K01424 GO:0003674,GO:0003824,GO:0004067,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0034641,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0071704,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 452.0
HKD2_k127_5033163_4 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000000000000000000006103 184.0
HKD2_k127_5033163_5 YsiA-like protein, C-terminal region K13770 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000004668 138.0
HKD2_k127_5038349_0 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.155e-213 672.0
HKD2_k127_5038349_1 peptidase M42 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 595.0
HKD2_k127_5038349_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 334.0
HKD2_k127_5038349_3 general stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001172 223.0
HKD2_k127_5038836_0 Four helix bundle sensory module for signal transduction K03407 - 2.7.13.3 0.0 1165.0
HKD2_k127_5038836_1 His Kinase A (phosphoacceptor) domain - - - 1.413e-287 897.0
HKD2_k127_5038836_2 chemotaxis K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 406.0
HKD2_k127_5038836_3 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 390.0
HKD2_k127_5038836_4 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 335.0
HKD2_k127_5038836_5 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K00087,K07402 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 296.0
HKD2_k127_5038836_6 MobA-like NTP transferase domain K00087,K07141 - 1.17.1.4,2.7.7.76 0.000000000000000000000000000000000002125 145.0
HKD2_k127_5038836_7 - - - - 0.0000000000001315 70.0
HKD2_k127_504182_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008719 407.0
HKD2_k127_504182_1 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001301 270.0
HKD2_k127_504182_2 effector of murein hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002154 268.0
HKD2_k127_504182_3 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000000000001391 204.0
HKD2_k127_504182_4 LrgA family K06518 - - 0.00000000000000000000000001412 113.0
HKD2_k127_504182_5 - - - - 0.0000000008919 62.0
HKD2_k127_504182_6 - - - - 0.000000002081 59.0
HKD2_k127_5049558_0 COG1333 ResB protein required for cytochrome c biosynthesis K07399 - - 1.511e-255 797.0
HKD2_k127_5049558_1 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component' - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 580.0
HKD2_k127_5049558_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 351.0
HKD2_k127_5049558_3 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 295.0
HKD2_k127_505206_0 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16164 - 3.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 541.0
HKD2_k127_505206_1 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008483 268.0
HKD2_k127_505206_2 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000103 116.0
HKD2_k127_5070127_0 COG0671 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000001771 243.0
HKD2_k127_5070127_1 - - - - 0.000000000000006363 81.0
HKD2_k127_5070127_2 - - - - 0.00000000000002867 76.0
HKD2_k127_5070127_3 Integrase core domain - - - 0.00000000000004632 76.0
HKD2_k127_5070127_4 - - - - 0.0000000004347 63.0
HKD2_k127_5070127_5 - - - - 0.000000005624 61.0
HKD2_k127_5105127_0 multicopper oxidases K06324 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114 1.16.3.3 0.0 2217.0
HKD2_k127_5105127_1 Circularly permuted ATP-grasp type 2 - - - 2.715e-211 666.0
HKD2_k127_5105127_11 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000004026 242.0
HKD2_k127_5105127_12 COG1388 FOG LysM repeat K19220,K19224 - - 0.00000000000000000000000000000000000000000000000000001389 201.0
HKD2_k127_5105127_13 Leucine-rich repeat (LRR) protein - - - 0.0000000000000000000000000000000000000000001339 175.0
HKD2_k127_5105127_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000008131 144.0
HKD2_k127_5105127_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 3.574e-198 620.0
HKD2_k127_5105127_3 COG2270 Permeases of the major facilitator superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 548.0
HKD2_k127_5105127_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 411.0
HKD2_k127_5105127_5 - K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 407.0
HKD2_k127_5105127_6 Phosphate K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 393.0
HKD2_k127_5105127_7 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 388.0
HKD2_k127_5105127_8 Bacterial transglutaminase-like N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 327.0
HKD2_k127_5105127_9 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006668 280.0
HKD2_k127_5105498_0 Polysaccharide biosynthesis protein K19421 GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192 - 3.32e-283 881.0
HKD2_k127_5105498_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 501.0
HKD2_k127_5105498_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000007519 100.0
HKD2_k127_5127811_0 Glycosyl transferase family group 2 - - - 0.0 1296.0
HKD2_k127_5127811_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 472.0
HKD2_k127_5127811_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 310.0
HKD2_k127_5127811_3 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000158 239.0
HKD2_k127_5127811_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000002048 219.0
HKD2_k127_5127811_5 abc transporter atp-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000001282 205.0
HKD2_k127_5127811_6 Zn-dependent - - - 0.00000000000000000000000000001374 120.0
HKD2_k127_5127811_7 COG2801 Transposase and inactivated derivatives K07497 - - 0.000000004514 57.0
HKD2_k127_5127811_8 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.000000236 52.0
HKD2_k127_5170871_0 HI0933-like protein K07007 - - 2.264e-246 764.0
HKD2_k127_5170871_1 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid K03328 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 5.413e-232 728.0
HKD2_k127_5170871_10 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003138 237.0
HKD2_k127_5170871_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000000000000000000000000000000001127 206.0
HKD2_k127_5170871_12 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000001098 199.0
HKD2_k127_5170871_13 COG1349 Transcriptional regulators of sugar metabolism - - - 0.0000000000000000000000000000000000001301 141.0
HKD2_k127_5170871_14 YtzH-like protein - - - 0.00000000000000000000000000000000006938 136.0
HKD2_k127_5170871_15 EamA-like transporter family - - - 0.0000000000000000000000001641 108.0
HKD2_k127_5170871_16 - - - - 0.00000000007678 66.0
HKD2_k127_5170871_17 - - - - 0.00000007717 57.0
HKD2_k127_5170871_2 Dipeptidase K01439 - 3.5.1.18 4.239e-229 716.0
HKD2_k127_5170871_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 453.0
HKD2_k127_5170871_4 chemotaxis protein K06595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 450.0
HKD2_k127_5170871_5 Phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 430.0
HKD2_k127_5170871_6 Belongs to the pseudouridine synthase RsuA family K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 400.0
HKD2_k127_5170871_7 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 384.0
HKD2_k127_5170871_8 dithiol-disulfide isomerase involved in polyketide biosynthesis K01829 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 342.0
HKD2_k127_5170871_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 308.0
HKD2_k127_5175277_0 ABC transporter - - - 2.128e-244 764.0
HKD2_k127_5175277_1 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 442.0
HKD2_k127_5175277_3 HicB family - - - 0.00000000000000000000000000000000000000000000000000000000000000007204 223.0
HKD2_k127_5175277_4 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000000000000000000000000009966 210.0
HKD2_k127_5175277_5 addiction module antidote protein - - - 0.00000000000000000000000000000000000000000000000000002488 189.0
HKD2_k127_5175277_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000000000000000000000002631 169.0
HKD2_k127_5175277_7 - - - - 0.000000000000000000000000000000000000000009367 154.0
HKD2_k127_5185276_0 Catalyzes the interconversion of 2-phosphoglycerate and K15633 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 2.447e-295 910.0
HKD2_k127_5185276_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 368.0
HKD2_k127_5185276_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000008674 207.0
HKD2_k127_5185276_3 Belongs to the phosphoglycerate kinase family K00927 GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 0.000000000000000000000000000000000000000007484 154.0
HKD2_k127_520342_0 glycoside hydrolase family 2 sugar binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 595.0
HKD2_k127_520342_1 Psort location Cytoplasmic, score K02529 - - 0.000000000000000000000000000000008185 129.0
HKD2_k127_5204907_0 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes K05592 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 9.648e-264 817.0
HKD2_k127_5204907_1 Transcriptional regulator - - - 6.919e-200 634.0
HKD2_k127_5204907_2 Protein of unknown function (DUF1456) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 293.0
HKD2_k127_5204907_3 Uncharacterized protein conserved in bacteria (DUF2187) - - - 0.00000000000000000001628 92.0
HKD2_k127_522011_0 isocitrate K00031 - 1.1.1.42 4.734e-254 786.0
HKD2_k127_522011_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 538.0
HKD2_k127_522011_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 483.0
HKD2_k127_522011_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002748 259.0
HKD2_k127_5228758_0 Flavodoxin-like fold K19784 - - 0.000000000001151 68.0
HKD2_k127_5228758_1 GYD domain - - - 0.00005518 49.0
HKD2_k127_5243797_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000002437 220.0
HKD2_k127_5243797_1 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000003236 194.0
HKD2_k127_5243797_2 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000009879 188.0
HKD2_k127_5243797_3 - - - - 0.00000000000000000000000000000000000000000000000001804 187.0
HKD2_k127_5248029_0 COG2183 Transcriptional accessory protein K06959 - - 0.0 1175.0
HKD2_k127_5248029_1 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity K05592 GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 2.31e-274 849.0
HKD2_k127_5248029_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 311.0
HKD2_k127_5248029_11 membrane protein (homolog of Drosophila rhomboid) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006289 267.0
HKD2_k127_5248029_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003773 258.0
HKD2_k127_5248029_13 Transcriptional regulator - GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000008349 255.0
HKD2_k127_5248029_14 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000000000000000000000000000000000002515 229.0
HKD2_k127_5248029_15 Belongs to the SprT family K03095 - - 0.00000000000000000000000000000000000000000000000000000000000000001441 227.0
HKD2_k127_5248029_16 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000009531 167.0
HKD2_k127_5248029_17 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain K07723 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000413 159.0
HKD2_k127_5248029_18 Bacterial PH domain K09167 - - 0.00000000000000000000000000000000008997 138.0
HKD2_k127_5248029_19 - - - - 0.0000000000001251 71.0
HKD2_k127_5248029_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 2.823e-207 653.0
HKD2_k127_5248029_20 - - - - 0.00000000007315 63.0
HKD2_k127_5248029_21 - - - - 0.0000000004921 60.0
HKD2_k127_5248029_22 - - - - 0.000000001492 58.0
HKD2_k127_5248029_23 - - - - 0.000000001938 59.0
HKD2_k127_5248029_25 - - - - 0.000001225 51.0
HKD2_k127_5248029_26 protein containing a divergent version of the methyl-accepting chemotaxis-like domain - - - 0.0009687 42.0
HKD2_k127_5248029_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 543.0
HKD2_k127_5248029_4 Membrane K08981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 532.0
HKD2_k127_5248029_5 COG2834 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 521.0
HKD2_k127_5248029_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775,K20707 - 5.1.1.1,5.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 517.0
HKD2_k127_5248029_7 Protoglobin K06595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 489.0
HKD2_k127_5248029_8 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 445.0
HKD2_k127_5248029_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 356.0
HKD2_k127_5249846_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 357.0
HKD2_k127_5249846_1 Cell wall K01449 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009827 269.0
HKD2_k127_5249846_2 UPF0316 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001243 269.0
HKD2_k127_5249846_3 - - - - 0.0000000000000000000002508 97.0
HKD2_k127_5282870_0 COG0008 Glutamyl- and glutaminyl-tRNA synthetases K01886 - 6.1.1.18 0.0 1012.0
HKD2_k127_5282870_1 Belongs to the FGGY kinase family K00851 - 2.7.1.12 3.465e-242 756.0
HKD2_k127_5282870_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 501.0
HKD2_k127_5282870_3 COG0665 Glycine D-amino acid oxidases (deaminating) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000004068 245.0
HKD2_k127_5282870_4 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006136 246.0
HKD2_k127_5282870_5 RNA polymerase K03088 - - 0.000000000000000000000000000000000009934 138.0
HKD2_k127_5282870_6 Domain of unknown function (DUF4179) - - - 0.0000000000000000000000000000000531 128.0
HKD2_k127_5282870_7 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000000000000000005132 120.0
HKD2_k127_5282870_8 Domain of unknown function (DUF4179) - - - 0.00000000000000007747 81.0
HKD2_k127_5282870_9 - - - - 0.00000001023 56.0
HKD2_k127_531647_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.0 1512.0
HKD2_k127_531647_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.155e-253 786.0
HKD2_k127_531647_2 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation K07067 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 582.0
HKD2_k127_531647_3 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity K19405 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 534.0
HKD2_k127_531647_4 protein with conserved CXXC pairs K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 292.0
HKD2_k127_531647_5 Belongs to the CtsR family K03708 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001922 258.0
HKD2_k127_5322332_0 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002571 272.0
HKD2_k127_5322332_1 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000348 241.0
HKD2_k127_5322332_2 Transposase K07483 - - 0.00000000000000000000000000000000000000000000000000000000006225 205.0
HKD2_k127_5322332_3 Integrase core domain K07497 - - 0.000000000000000000000000000000000000001224 147.0
HKD2_k127_5322332_4 Putative transposase of IS4/5 family (DUF4096) - - - 0.000000000000000000000000001006 115.0
HKD2_k127_5322332_5 Integrase core domain K07497 - - 0.00000000000000000000008162 99.0
HKD2_k127_5322332_6 Competence protein ComEC K02238 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000001108 72.0
HKD2_k127_5322332_7 Glutathione S-transferase, C-terminal domain - - - 0.000000237 53.0
HKD2_k127_533480_0 Repeat of Unknown Function (DUF347) - - - 1.627e-208 653.0
HKD2_k127_533480_1 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 589.0
HKD2_k127_533480_10 phospholipid phosphatase K19302 - 3.6.1.27 0.000000000000000002392 84.0
HKD2_k127_533480_13 - - - - 0.000000003827 59.0
HKD2_k127_533480_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 306.0
HKD2_k127_533480_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009546 240.0
HKD2_k127_533480_4 - - - - 0.00000000000000000000000000000000000000000000000002947 185.0
HKD2_k127_533480_5 WHG domain - - - 0.0000000000000000000000000000000000000000000000001494 183.0
HKD2_k127_533480_6 COG0671 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000001262 167.0
HKD2_k127_533480_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000003157 159.0
HKD2_k127_533480_8 Abortive infection protein K07052 - - 0.00000000000000000000000000000000004569 144.0
HKD2_k127_533480_9 Repeat of Unknown Function (DUF347) - - - 0.0000000000000000000000356 100.0
HKD2_k127_5347953_0 Xylose isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 591.0
HKD2_k127_5347953_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 591.0
HKD2_k127_5347953_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 435.0
HKD2_k127_5347953_3 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 408.0
HKD2_k127_5347953_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 398.0
HKD2_k127_5347953_5 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 312.0
HKD2_k127_5347953_6 - - - - 0.000000000000000000000000000000000000000000000000000000000002384 216.0
HKD2_k127_5347953_8 - - - - 0.000000000414 61.0
HKD2_k127_5357658_0 homoserine dehydrogenase K00003 - 1.1.1.3 8.39e-220 687.0
HKD2_k127_5357658_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 602.0
HKD2_k127_5357658_10 Belongs to the UPF0349 family - - - 0.00000000000000000000000000001782 118.0
HKD2_k127_5357658_11 Uncharacterized protein conserved in bacteria (DUF2225) K09766 - - 0.0000000007082 61.0
HKD2_k127_5357658_2 NADH dehydrogenase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 584.0
HKD2_k127_5357658_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 488.0
HKD2_k127_5357658_4 Spore coat protein - GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 473.0
HKD2_k127_5357658_5 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro K01101 - 3.1.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 403.0
HKD2_k127_5357658_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 322.0
HKD2_k127_5357658_7 COG1267 Phosphatidylglycerophosphatase A and related proteins K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003791 275.0
HKD2_k127_5357658_8 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000002822 169.0
HKD2_k127_5357658_9 COG0694 Thioredoxin-like proteins and domains - - - 0.0000000000000000000000000000000000000002384 150.0
HKD2_k127_5359286_0 chemotaxis protein K03406 - - 0.000000000000000000000000000000000000002112 159.0
HKD2_k127_5359286_1 chemotaxis K03406 - - 0.000000000004275 70.0
HKD2_k127_5359286_2 chemotaxis protein K03406 - - 0.00000000009322 67.0
HKD2_k127_5367542_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 522.0
HKD2_k127_5367542_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 GO:0003674,GO:0005215 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 511.0
HKD2_k127_5367542_10 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01911 - 6.2.1.26 0.0000000000000000000000000000000000002125 141.0
HKD2_k127_5367542_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000000000006032 139.0
HKD2_k127_5367542_13 Protein of unknown function (DUF3006) - - - 0.00000000000000000000000205 103.0
HKD2_k127_5367542_14 - - - - 0.000000000000006439 76.0
HKD2_k127_5367542_15 Domain of Unknown Function (DUF1540) - - - 0.000000000002844 67.0
HKD2_k127_5367542_17 Tumour necrosis factor receptor superfamily member 19 - - - 0.0004226 45.0
HKD2_k127_5367542_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 491.0
HKD2_k127_5367542_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 421.0
HKD2_k127_5367542_4 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 419.0
HKD2_k127_5367542_5 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 421.0
HKD2_k127_5367542_6 ATPases associated with a variety of cellular activities K02049,K10831,K15555 - 3.6.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 293.0
HKD2_k127_5367542_7 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 GO:0008150,GO:0043900,GO:0043901,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900191,GO:1900231,GO:1900232 4.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002162 269.0
HKD2_k127_5367542_8 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000007344 199.0
HKD2_k127_5367542_9 - - - - 0.00000000000000000000000000000000000000000000000004382 179.0
HKD2_k127_5386098_0 Ammonium transporter K03320 - - 7.601e-229 713.0
HKD2_k127_5386098_1 Belongs to the TelA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 586.0
HKD2_k127_5386098_10 - - - - 0.00002443 47.0
HKD2_k127_5386098_11 Histidine kinase - - - 0.0002405 44.0
HKD2_k127_5386098_2 Transcriptional regulator - GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 458.0
HKD2_k127_5386098_3 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 444.0
HKD2_k127_5386098_4 5-bromo-4-chloroindolyl phosphate hydrolysis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009566 243.0
HKD2_k127_5386098_5 - - - - 0.0000000000000000000000000000000000000000000000000003062 188.0
HKD2_k127_5386098_6 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000002016 177.0
HKD2_k127_5386098_7 Helix-turn-helix domain - - - 0.000000000000000000000000000000005592 128.0
HKD2_k127_5386098_8 - - - - 0.00000000000000000000000000000001295 130.0
HKD2_k127_5386098_9 - - - - 0.0000000000000369 72.0
HKD2_k127_5389591_0 Protein of unknown function (DUF445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 475.0
HKD2_k127_5389591_1 Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 392.0
HKD2_k127_5389591_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000494 285.0
HKD2_k127_5389591_3 COG0672 High-affinity Fe2 Pb2 permease K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002059 251.0
HKD2_k127_5389591_4 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000000000000000000000000000009081 219.0
HKD2_k127_5389591_5 COG0477 Permeases of the major facilitator superfamily - - - 0.00006381 46.0
HKD2_k127_5403516_0 Copper amine oxidase, enzyme domain K00276 - 1.4.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 467.0
HKD2_k127_5403516_1 Prokaryotic glutathione synthetase, ATP-grasp domain K05844,K14940 - 6.3.2.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 451.0
HKD2_k127_5403516_2 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 429.0
HKD2_k127_5403516_3 RimK-like ATP-grasp domain K05844,K14940 - 6.3.2.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 376.0
HKD2_k127_5403516_4 - - - - 0.000000000000000000000000000000003716 135.0
HKD2_k127_5413782_0 Ribosomal protein S1 K02945 - - 2.552e-204 640.0
HKD2_k127_5413782_1 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 290.0
HKD2_k127_5413782_2 - - - - 0.0000000000000000000000000000000000000004674 152.0
HKD2_k127_5413782_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000001727 79.0
HKD2_k127_5413782_4 YpzI-like protein - - - 0.00000000001081 65.0
HKD2_k127_5413782_5 - - - - 0.000001741 53.0
HKD2_k127_5418291_0 oligoendopeptidase - - - 4.618e-285 884.0
HKD2_k127_5418291_1 COG0477 Permeases of the major facilitator superfamily K08223 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 569.0
HKD2_k127_5418291_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008242 284.0
HKD2_k127_5418291_3 transcriptional K15973 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000002831 245.0
HKD2_k127_5421073_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 2000.0
HKD2_k127_5421073_1 Belongs to the UPF0358 family - - - 0.000000000000000000000000000000000000000000006321 164.0
HKD2_k127_5425370_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776,K02428 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 425.0
HKD2_k127_5425370_1 Recombinase - - - 0.000000000000000000000000001034 114.0
HKD2_k127_5425370_2 COG5401 Spore germination protein K06298 - - 0.00000000000000000000000002365 110.0
HKD2_k127_5425370_3 LuxR family transcriptional regulator K01994 - - 0.0000000006665 59.0
HKD2_k127_5426359_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 1.804e-227 707.0
HKD2_k127_5426359_1 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000001172 220.0
HKD2_k127_5426359_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000006045 76.0
HKD2_k127_5428613_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 364.0
HKD2_k127_5428613_1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) K17763 - - 0.00000000000000000000000000000000000000000000000396 175.0
HKD2_k127_5431723_0 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 334.0
HKD2_k127_5431723_1 - - - - 0.00000000000000000000000000000000000000000000000008593 180.0
HKD2_k127_5431723_2 FAD binding domain - - - 0.000000000000000000000000000000000000000000000004201 178.0
HKD2_k127_5431723_3 - - - - 0.00000000000000000000000000000000000000003707 156.0
HKD2_k127_5431723_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation - - - 0.0000000000000000000000000000000000000002402 155.0
HKD2_k127_5431723_5 Aminotransferase K10206 - 2.6.1.83 0.0002559 44.0
HKD2_k127_5434428_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 7.156e-216 672.0
HKD2_k127_5434428_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 568.0
HKD2_k127_5434428_10 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein K09787 GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000000005936 186.0
HKD2_k127_5434428_11 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000002847 171.0
HKD2_k127_5434428_12 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000002558 129.0
HKD2_k127_5434428_13 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000000000847 128.0
HKD2_k127_5434428_14 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0009645 43.0
HKD2_k127_5434428_2 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 508.0
HKD2_k127_5434428_3 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 499.0
HKD2_k127_5434428_4 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 436.0
HKD2_k127_5434428_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 386.0
HKD2_k127_5434428_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 287.0
HKD2_k127_5434428_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003283 264.0
HKD2_k127_5434428_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000003091 218.0
HKD2_k127_5434428_9 YlqD protein - - - 0.0000000000000000000000000000000000000000000000000000000003131 205.0
HKD2_k127_5437839_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 1.503e-240 752.0
HKD2_k127_5437839_1 oxidase, subunit K00425 - 1.10.3.14 4.737e-231 721.0
HKD2_k127_5437839_10 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000008576 70.0
HKD2_k127_5437839_11 - - - - 0.00000000005993 64.0
HKD2_k127_5437839_13 Belongs to the enoyl-CoA hydratase isomerase family K15016 - 1.1.1.35,4.2.1.17 0.00073 44.0
HKD2_k127_5437839_14 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0009165 42.0
HKD2_k127_5437839_2 Acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 603.0
HKD2_k127_5437839_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 586.0
HKD2_k127_5437839_4 COG1294 Cytochrome bd-type quinol oxidase, subunit 2 K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 522.0
HKD2_k127_5437839_5 Phage integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 451.0
HKD2_k127_5437839_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005611 256.0
HKD2_k127_5437839_7 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002685 234.0
HKD2_k127_5437839_8 - K10798 - 2.4.2.30 0.00000000000000000000000000000000000000008597 159.0
HKD2_k127_5437839_9 Protein of unknown function (DUF2533) - - - 0.00000000000000000000001044 102.0
HKD2_k127_5438426_0 Signal transduction histidine kinase regulating citrate malate K02476,K11614,K11691 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 615.0
HKD2_k127_5438426_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102,K11103 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 582.0
HKD2_k127_5438426_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 286.0
HKD2_k127_5442047_0 GTP-binding protein TypA K06207 - - 0.0 1082.0
HKD2_k127_5442047_1 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 9.683e-246 763.0
HKD2_k127_5442047_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.0000000000000000000000000000000000000000000000000000000000000000002113 235.0
HKD2_k127_5442047_3 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) - - - 0.000000000000000000000000000000000000000000000000000000000004008 213.0
HKD2_k127_5442047_4 YlaH-like protein - - - 0.00000000000000000000000000000000000000000000001977 171.0
HKD2_k127_5442047_5 protein conserved in bacteria - - - 0.00000000000000000000000000001223 118.0
HKD2_k127_5442047_6 Family of unknown function (DUF5325) - - - 0.000001171 52.0
HKD2_k127_5486095_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 465.0
HKD2_k127_5486095_1 COG0346 Lactoylglutathione lyase and related lyases K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 459.0
HKD2_k127_5486095_2 Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 308.0
HKD2_k127_5486095_3 DoxX K15977 - - 0.000000000000000000000000009055 109.0
HKD2_k127_5491533_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 1.531e-256 800.0
HKD2_k127_5491533_1 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid K06409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005485 350.0
HKD2_k127_5491533_2 Post-transcriptional regulator - - - 0.0000000000000000000000000000000000000001042 153.0
HKD2_k127_5502463_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 1.101e-234 731.0
HKD2_k127_5502463_1 acyl-CoA dehydrogenase K00248 - 1.3.8.1 4.813e-220 686.0
HKD2_k127_5502463_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 319.0
HKD2_k127_5502463_3 - - - - 0.000002897 49.0
HKD2_k127_5503678_0 Permease family K06901 - - 3.543e-210 660.0
HKD2_k127_5503678_1 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001312 252.0
HKD2_k127_5503678_2 XdhC and CoxI family - - - 0.0000000000000000000000000000000002458 134.0
HKD2_k127_5516081_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1341.0
HKD2_k127_5516081_1 Copper amine oxidase N-terminal domain - - - 0.0000000000000000000000000001854 125.0
HKD2_k127_5516081_2 ApbE family K03734 - 2.7.1.180 0.00000000000004131 74.0
HKD2_k127_5516081_3 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000006974 65.0
HKD2_k127_5516081_4 - - - - 0.00001151 53.0
HKD2_k127_5561683_0 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 4.085e-196 616.0
HKD2_k127_5561683_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 414.0
HKD2_k127_5561683_2 SAM-dependent methyltransferase K06967 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 332.0
HKD2_k127_5561683_3 COG2010 Cytochrome c, mono- and diheme variants K13300 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000002876 167.0
HKD2_k127_5561683_4 - - - - 0.00000000000000000000000000000001307 136.0
HKD2_k127_5579427_0 Chain length determinant protein - - - 0.00000000000000000000000000003 127.0
HKD2_k127_5579427_1 Nucleotidyl transferase - - - 0.000000000000000002139 87.0
HKD2_k127_5579427_2 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00978 - 2.7.7.33 0.0000168 47.0
HKD2_k127_5639956_0 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities K14155 - 4.4.1.8 2.572e-225 702.0
HKD2_k127_5639956_1 - - - - 0.000000000000000000000000000000000000009153 151.0
HKD2_k127_5639956_2 Spo0E like sporulation regulatory protein - - - 0.00002471 48.0
HKD2_k127_5654456_0 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 417.0
HKD2_k127_5654456_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 404.0
HKD2_k127_5654456_2 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000008142 185.0
HKD2_k127_5654456_3 Transposase IS200 like - - - 0.00000000004451 64.0
HKD2_k127_5668_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03169 - 5.99.1.2 0.0 1076.0
HKD2_k127_5668_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 6.257e-309 950.0
HKD2_k127_5668_2 HMGL-like K01666 - 4.1.3.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 603.0
HKD2_k127_5668_3 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 564.0
HKD2_k127_5668_5 2TM domain - - - 0.000000007852 57.0
HKD2_k127_569434_0 - - - - 4.663e-309 952.0
HKD2_k127_569434_1 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 552.0
HKD2_k127_569434_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 535.0
HKD2_k127_569434_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000007299 212.0
HKD2_k127_569434_4 GtrA-like protein - - - 0.0000000000000000000000000000000000000000000000000001868 188.0
HKD2_k127_569434_5 - - - - 0.000001301 50.0
HKD2_k127_570007_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 2.34e-263 814.0
HKD2_k127_570007_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 9.577e-250 779.0
HKD2_k127_570007_10 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000003862 229.0
HKD2_k127_570007_11 Histidine phosphatase superfamily (branch 1) K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000001446 183.0
HKD2_k127_570007_12 COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000005434 133.0
HKD2_k127_570007_13 Cobinamide kinase / cobinamide phosphate guanyltransferase - - - 0.000000000006347 68.0
HKD2_k127_570007_2 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 1.122e-237 743.0
HKD2_k127_570007_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 499.0
HKD2_k127_570007_4 COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 495.0
HKD2_k127_570007_5 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 444.0
HKD2_k127_570007_6 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 414.0
HKD2_k127_570007_7 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 392.0
HKD2_k127_570007_8 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 382.0
HKD2_k127_570007_9 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 306.0
HKD2_k127_5703002_0 Ser protein kinase K07180 - - 0.0 1080.0
HKD2_k127_5703002_1 Belongs to the UPF0229 family K09786 - - 1.405e-229 713.0
HKD2_k127_5703002_2 Na -dependent transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 409.0
HKD2_k127_5703002_3 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 310.0
HKD2_k127_5703002_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 292.0
HKD2_k127_5703002_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000001085 211.0
HKD2_k127_5703002_6 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.000000000000002635 77.0
HKD2_k127_5711034_0 Belongs to the 5'-nucleotidase family K01119,K08693 - 3.1.3.5,3.1.3.6,3.1.4.16 0.0 1810.0
HKD2_k127_5711034_1 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.0 1285.0
HKD2_k127_5711034_10 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 610.0
HKD2_k127_5711034_11 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 579.0
HKD2_k127_5711034_12 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase K07029 GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 526.0
HKD2_k127_5711034_13 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 484.0
HKD2_k127_5711034_14 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 427.0
HKD2_k127_5711034_15 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 401.0
HKD2_k127_5711034_16 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales K07094 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 391.0
HKD2_k127_5711034_17 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 318.0
HKD2_k127_5711034_18 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 285.0
HKD2_k127_5711034_19 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778,K13531 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000001279 263.0
HKD2_k127_5711034_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0 1100.0
HKD2_k127_5711034_20 COG0672 High-affinity Fe2 Pb2 permease K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001606 249.0
HKD2_k127_5711034_21 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000171 186.0
HKD2_k127_5711034_22 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000005504 189.0
HKD2_k127_5711034_23 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000001542 163.0
HKD2_k127_5711034_24 Psort location CytoplasmicMembrane, score K01990,K19340 - - 0.000000000000000000000000000009996 121.0
HKD2_k127_5711034_25 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000002278 108.0
HKD2_k127_5711034_26 - - - - 0.0000000000000000000000003544 106.0
HKD2_k127_5711034_27 Bacterial protein of unknown function (DUF839) K07093 - - 0.000000000000000001626 85.0
HKD2_k127_5711034_28 Domain of unknown function (DUF4062) - - - 0.000004436 49.0
HKD2_k127_5711034_29 - - - - 0.000006373 49.0
HKD2_k127_5711034_3 adenine deaminase K01486 GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 2.189e-314 969.0
HKD2_k127_5711034_30 ABC-2 family transporter protein K01992 - - 0.00001476 48.0
HKD2_k127_5711034_31 Bacterial protein of unknown function (DUF839) K07093 - - 0.00001629 48.0
HKD2_k127_5711034_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 5.047e-293 902.0
HKD2_k127_5711034_5 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.597e-292 901.0
HKD2_k127_5711034_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 3.212e-262 812.0
HKD2_k127_5711034_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 1.815e-239 746.0
HKD2_k127_5711034_8 Belongs to the GARS family K01945 - 6.3.4.13 2.04e-218 683.0
HKD2_k127_5711034_9 COG4851 Protein involved in sex pheromone biosynthesis - - - 2.805e-204 640.0
HKD2_k127_5764299_0 sporulation protein K06313 - - 1.468e-212 667.0
HKD2_k127_5764299_1 COG0492 Thioredoxin reductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 504.0
HKD2_k127_5764299_2 Spore cortex-lytic enzyme K01449 GO:0005575,GO:0005623,GO:0042763,GO:0044464 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 457.0
HKD2_k127_5764299_3 Involved in the degradation of specific anti-sigma factors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 333.0
HKD2_k127_5764299_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 313.0
HKD2_k127_5764299_5 Flagellar protein YcgR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004876 247.0
HKD2_k127_5770871_0 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 409.0
HKD2_k127_5770871_1 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003164 241.0
HKD2_k127_5770871_2 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000001073 219.0
HKD2_k127_5779400_0 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 4.592e-237 743.0
HKD2_k127_5779400_1 Belongs to the UPF0348 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 427.0
HKD2_k127_5779400_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 353.0
HKD2_k127_5779400_3 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 323.0
HKD2_k127_5779400_4 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 295.0
HKD2_k127_5779400_5 n-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001072 247.0
HKD2_k127_5779400_6 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains K06314 - - 0.00000000000000000000000000000000000000000000000000000000000005468 219.0
HKD2_k127_5779400_7 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000005491 160.0
HKD2_k127_5779400_8 Protein of unknown function (DUF3397) - - - 0.000000000000000000000000000000000003766 142.0
HKD2_k127_5779400_9 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000001369 123.0
HKD2_k127_5791546_0 Belongs to the pirin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 578.0
HKD2_k127_5791546_1 chemotaxis protein K06595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 439.0
HKD2_k127_5791546_2 Chemotaxis phosphatase CheX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 417.0
HKD2_k127_5791546_3 NAD(P)H dehydrogenase K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 351.0
HKD2_k127_5791546_4 diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000000000000000000001096 229.0
HKD2_k127_5791546_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000001109 212.0
HKD2_k127_5791546_6 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000002025 201.0
HKD2_k127_5791546_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000002205 130.0
HKD2_k127_5791546_8 - - - - 0.00005401 46.0
HKD2_k127_5791561_0 Bacterial extracellular solute-binding protein K02027 - - 2.902e-246 766.0
HKD2_k127_5791561_1 amino acid activation for nonribosomal peptide biosynthetic process K20951 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 431.0
HKD2_k127_5791561_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 457.0
HKD2_k127_5791561_3 Catalyzes the desulfonation of aliphatic sulfonates K04091 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005515,GO:0006082,GO:0006790,GO:0006950,GO:0008150,GO:0008152,GO:0008726,GO:0009056,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016712,GO:0019694,GO:0042802,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0046306,GO:0050896,GO:0055114,GO:0071704,GO:1901575 1.14.14.5 0.000000000000003992 76.0
HKD2_k127_5792991_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 1.495e-206 651.0
HKD2_k127_5792991_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001052 269.0
HKD2_k127_5792991_2 PFAM membrane bound O-acyl transferase MBOAT family protein K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006014 254.0
HKD2_k127_5792991_3 - K06325 - - 0.00000000000000000000000000000000001553 146.0
HKD2_k127_5817171_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.051e-277 858.0
HKD2_k127_5817171_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 572.0
HKD2_k127_5817171_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 529.0
HKD2_k127_5817171_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 482.0
HKD2_k127_5817171_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 420.0
HKD2_k127_5817171_5 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003145 259.0
HKD2_k127_5817171_6 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000006398 246.0
HKD2_k127_5817171_7 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000001052 184.0
HKD2_k127_5817171_8 sequence-specific DNA binding - - - 0.0000000000008603 70.0
HKD2_k127_5820901_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 526.0
HKD2_k127_5820901_1 permeases K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 450.0
HKD2_k127_5820901_2 membrane K08986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 448.0
HKD2_k127_5820901_3 Amino acid permease - - - 0.00000000000000008817 81.0
HKD2_k127_5821557_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 482.0
HKD2_k127_5821557_1 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 423.0
HKD2_k127_5821557_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 387.0
HKD2_k127_5821557_3 BioY family K03523 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000001249 200.0
HKD2_k127_5821557_4 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes K05592 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.0000000000000000000000000000000000000000001727 160.0
HKD2_k127_5821557_5 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000987 48.0
HKD2_k127_5824439_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 473.0
HKD2_k127_5824439_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 401.0
HKD2_k127_5824439_12 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase K03429 - 2.4.1.315 0.000000000000000001086 88.0
HKD2_k127_5824439_13 - - - - 0.0000000008801 60.0
HKD2_k127_5824439_2 Predicted nucleotidyltransferase K07074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 395.0
HKD2_k127_5824439_3 PAS fold K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 360.0
HKD2_k127_5824439_4 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 294.0
HKD2_k127_5824439_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000003595 215.0
HKD2_k127_5824439_6 PHP domain K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000005082 197.0
HKD2_k127_5824439_7 - - - - 0.00000000000000000000000000000000000000000000000001056 182.0
HKD2_k127_5824439_9 Soluble P-type ATPase - - - 0.0000000000000000000000000000000000000002726 154.0
HKD2_k127_5839915_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0 1153.0
HKD2_k127_5839915_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K16924 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 518.0
HKD2_k127_5839915_10 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000002269 174.0
HKD2_k127_5839915_11 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000003895 155.0
HKD2_k127_5839915_12 DNA topological change K06423 - - 0.000000000000000000000002731 102.0
HKD2_k127_5839915_13 - - - - 0.000003318 52.0
HKD2_k127_5839915_14 - - - - 0.00001929 46.0
HKD2_k127_5839915_2 peptidase K06436 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0031160,GO:0043591,GO:0043593,GO:0044426,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 498.0
HKD2_k127_5839915_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 483.0
HKD2_k127_5839915_4 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 480.0
HKD2_k127_5839915_5 pur operon repressor K09685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 465.0
HKD2_k127_5839915_6 hydrolase, TatD K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 451.0
HKD2_k127_5839915_7 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step K05985 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000003124 260.0
HKD2_k127_5839915_8 translation initiation inhibitor, yjgF family K09022 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019239,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046360,GO:0046361,GO:0046394,GO:0046459,GO:0051790,GO:0071704,GO:0072330,GO:1901576 3.5.99.10 0.0000000000000000000000000000000000000000000000000000000000000000004385 229.0
HKD2_k127_5839915_9 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation K06412 GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934 - 0.0000000000000000000000000000000000000000000000000000001087 195.0
HKD2_k127_5875037_0 DNA polymerase K02337 - 2.7.7.7 0.0 1307.0
HKD2_k127_5875037_1 Malate dehydrogenase K00027 - 1.1.1.38 1.628e-234 729.0
HKD2_k127_5875037_2 helix_turn_helix gluconate operon transcriptional repressor K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003657 269.0
HKD2_k127_5875037_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004466 236.0
HKD2_k127_5875037_4 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000007713 231.0
HKD2_k127_5875037_5 Sporulation protein YtrH - - - 0.000000000000000000000000000000000000000000000000000000003789 199.0
HKD2_k127_5875037_6 - - - - 0.00000001899 57.0
HKD2_k127_5892791_0 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 2.56e-230 722.0
HKD2_k127_5892791_1 Aminotransferase K08969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 585.0
HKD2_k127_5892791_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 426.0
HKD2_k127_5892791_3 Purine nucleoside phosphorylase K03784 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 414.0
HKD2_k127_5892791_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 355.0
HKD2_k127_5892791_5 YozD-like protein - - - 0.00000000000000000000008162 99.0
HKD2_k127_5892791_6 - - - - 0.0000006516 51.0
HKD2_k127_5892821_0 COG0475 Kef-type K transport systems, membrane components - - - 7.89e-233 725.0
HKD2_k127_5892821_1 Uncharacterised MFS-type transporter YbfB K05548 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 562.0
HKD2_k127_5892821_10 S-layer homology domain - - - 0.0000001495 60.0
HKD2_k127_5892821_2 COG0477 Permeases of the major facilitator superfamily K08221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 388.0
HKD2_k127_5892821_3 - - - - 0.0000000000000000000000000000000000000000001158 163.0
HKD2_k127_5892821_4 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000002476 143.0
HKD2_k127_5892821_6 Peptidase propeptide and YPEB domain - - - 0.0000000000000000000000002064 109.0
HKD2_k127_5892821_7 Belongs to the UPF0346 family - - - 0.000000000000000000000000264 106.0
HKD2_k127_5892821_8 CrcB-like protein, Camphor Resistance (CrcB) K06199 - - 0.0000000000000000000001036 101.0
HKD2_k127_5892821_9 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000009805 97.0
HKD2_k127_5902509_0 COG1363 Cellulase M and related proteins K01261,K01269 - 3.4.11.7 9.364e-216 672.0
HKD2_k127_5902509_1 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 612.0
HKD2_k127_5902509_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 467.0
HKD2_k127_5902509_3 Belongs to the UPF0354 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 442.0
HKD2_k127_5902509_4 Thioredoxin - GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000000000000000000004367 191.0
HKD2_k127_5902509_5 small secreted protein - - - 0.0000000000000000000000000000000000000003864 151.0
HKD2_k127_5902509_6 - - - - 0.0000000000000000000005437 96.0
HKD2_k127_5902509_9 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.00005724 46.0
HKD2_k127_5915909_0 O-methyltransferase K15256 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 401.0
HKD2_k127_5915909_1 Short-chain dehydrogenase reductase sdr K00034 - 1.1.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 346.0
HKD2_k127_5915909_10 - - - - 0.0004293 46.0
HKD2_k127_5915909_2 Belongs to the sigma-70 factor family K03088,K03091,K12296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 289.0
HKD2_k127_5915909_3 RNA binding protein (contains ribosomal protein S1 domain) K07571 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002864 240.0
HKD2_k127_5915909_4 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000000005636 136.0
HKD2_k127_5915909_5 Copper amine oxidase N-terminal domain - - - 0.000000000000000000000000000000008005 135.0
HKD2_k127_5915909_6 - - - - 0.0000000000000000000000000005392 113.0
HKD2_k127_5915909_8 - - - - 0.000001456 54.0
HKD2_k127_5931844_0 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase K01436 - - 5.253e-224 698.0
HKD2_k127_5931844_1 Histidine kinase - - - 4.276e-203 640.0
HKD2_k127_5931844_2 Multi-copper - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 378.0
HKD2_k127_5931844_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 369.0
HKD2_k127_5931844_4 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000003129 199.0
HKD2_k127_5931844_5 - - - - 0.000000002715 58.0
HKD2_k127_5932539_0 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis K06948 GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - 8.186e-221 687.0
HKD2_k127_5932539_1 cystathionine K01760,K17217 GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 3.69e-216 674.0
HKD2_k127_5932539_10 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 311.0
HKD2_k127_5932539_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 296.0
HKD2_k127_5932539_12 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 283.0
HKD2_k127_5932539_13 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001366 249.0
HKD2_k127_5932539_14 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000006828 214.0
HKD2_k127_5932539_15 hydrolase of the HAD superfamily K07015 - - 0.0000000000000000000000000000000000000000000000000000002008 199.0
HKD2_k127_5932539_16 COG1555 DNA uptake protein and related DNA-binding proteins K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000001787 199.0
HKD2_k127_5932539_17 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 - - 0.000000000000000000000000000000000000000000000000009082 181.0
HKD2_k127_5932539_18 YrhC-like protein - - - 0.00000000000003972 74.0
HKD2_k127_5932539_19 Sporulation inhibitor A K06371 - - 0.000000000000421 70.0
HKD2_k127_5932539_2 Cysteine synthase K01738,K17216 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 500.0
HKD2_k127_5932539_3 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 GO:0000003,GO:0000988,GO:0000990,GO:0003674,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 437.0
HKD2_k127_5932539_4 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 407.0
HKD2_k127_5932539_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 393.0
HKD2_k127_5932539_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K02239 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 383.0
HKD2_k127_5932539_7 Competence protein ComEC K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 347.0
HKD2_k127_5932539_8 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 341.0
HKD2_k127_5932539_9 COG2131 Deoxycytidylate deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 323.0
HKD2_k127_5943614_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 2.809e-274 856.0
HKD2_k127_5943614_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000001669 171.0
HKD2_k127_5987166_0 flagellar hook-associated protein K02396 - - 6.827e-210 664.0
HKD2_k127_5987166_1 Beta-eliminating lyase K13010 - 2.6.1.102 3.854e-199 625.0
HKD2_k127_5987166_10 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000000000000000001883 117.0
HKD2_k127_5987166_11 FlgN protein - - - 0.00000000001424 68.0
HKD2_k127_5987166_2 GDP-mannose 4,6 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 570.0
HKD2_k127_5987166_3 Protein of unknown function DUF115 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 501.0
HKD2_k127_5987166_4 Belongs to the bacterial flagellin family K02397 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 393.0
HKD2_k127_5987166_5 Cytidylyltransferase K07257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 323.0
HKD2_k127_5987166_6 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 311.0
HKD2_k127_5987166_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000007115 214.0
HKD2_k127_5987166_8 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00000000000000000000000000000000000000000000000000006057 190.0
HKD2_k127_5987166_9 - - - - 0.000000000000000000000000000000000000007525 152.0
HKD2_k127_6039360_0 lysine 2,3-aminomutase K01843 - 5.4.3.2 3.553e-267 824.0
HKD2_k127_6039360_1 Natural resistance-associated macrophage protein - - - 3.022e-205 652.0
HKD2_k127_6039360_2 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 411.0
HKD2_k127_6039360_3 YokU-like protein, putative antitoxin - - - 0.000000000000000000000000000000000000003839 148.0
HKD2_k127_6039360_4 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall K14188 GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 0.00000000000136 70.0
HKD2_k127_6072664_0 Nucleotidyltransferase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008853 463.0
HKD2_k127_6072664_1 Belongs to the Fur family K09825 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002822 274.0
HKD2_k127_6072664_2 Peroxiredoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000584 265.0
HKD2_k127_6072664_3 Ion transport K08713 - - 0.0000000000000000000000000000000000000000000000000000000000003572 213.0
HKD2_k127_6072664_4 UPF0295 protein - - - 0.0000000000000000000000000000000000000000000000000000000584 198.0
HKD2_k127_6072664_5 transport system, permease component K01992 - - 0.0000000000000002668 78.0
HKD2_k127_6080841_0 COG0826 Collagenase and related proteases K08303 - - 2.743e-242 752.0
HKD2_k127_6080841_1 Peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 520.0
HKD2_k127_6080841_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 502.0
HKD2_k127_6080841_3 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002271 282.0
HKD2_k127_6080841_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002016 255.0
HKD2_k127_6080841_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000008786 175.0
HKD2_k127_6080841_6 Belongs to the UPF0297 family - - - 0.00000000000000000000000000000000000000000000002017 171.0
HKD2_k127_6080841_7 Belongs to the UPF0473 family - - - 0.00000000000000000000000000000000000000000133 157.0
HKD2_k127_6080841_8 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000003487 72.0
HKD2_k127_6126042_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 2.233e-300 935.0
HKD2_k127_6126042_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 1.004e-248 773.0
HKD2_k127_6126042_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002656 241.0
HKD2_k127_6126042_3 Major Facilitator Superfamily - - - 0.00002471 48.0
HKD2_k127_6178568_0 helicase involved in DNA repair and perhaps also replication K03722 - 3.6.4.12 2.169e-309 973.0
HKD2_k127_6178568_1 EXOIII - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 346.0
HKD2_k127_6178568_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000001795 217.0
HKD2_k127_62500_0 Protein of unknown function (DUF3147) - - - 0.000000000000000000000000000000000000000000000007748 174.0
HKD2_k127_62500_1 Diguanylate cyclase, GGDEF domain K20971 - - 0.0000000000000000000000000000000000000000000000884 179.0
HKD2_k127_62500_2 Protein of unknown function (DUF3147) - - - 0.000000000000000000000000000000000000000000003762 166.0
HKD2_k127_62500_3 Cell division protein FtsJ - - - 0.00000000000000000000000000000000000000000009347 161.0
HKD2_k127_6254913_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007271 273.0
HKD2_k127_6254913_1 - - - - 0.000000000000000000000003076 106.0
HKD2_k127_6278540_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 GO:0003674,GO:0003824,GO:0003996,GO:0004321,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015645,GO:0016053,GO:0016405,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576 6.2.1.1 6.228e-274 850.0
HKD2_k127_6278540_1 -transporter K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 448.0
HKD2_k127_6278540_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000004515 254.0
HKD2_k127_6278540_3 spore protein K06419 - - 0.0000000000000000000000000000000009889 130.0
HKD2_k127_6278540_4 signal peptide peptidase SppA K04773 - - 0.000000000000000000009978 93.0
HKD2_k127_6313880_0 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 383.0
HKD2_k127_6313880_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 337.0
HKD2_k127_6313880_2 Two component transcriptional regulator, winged helix family K11521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004012 278.0
HKD2_k127_6313880_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000007927 226.0
HKD2_k127_6313880_4 ApbE family K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000005812 208.0
HKD2_k127_6313880_5 Heme biosynthesis protein HemY K13628,K15724 - - 0.0000000000000000000000000000000000000000000001758 169.0
HKD2_k127_6313880_6 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000001081 146.0
HKD2_k127_6331732_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 4.006e-300 924.0
HKD2_k127_6331732_1 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 5.978e-223 695.0
HKD2_k127_6331732_2 ferredoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 463.0
HKD2_k127_6331732_3 Spore coat protein K06328 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 317.0
HKD2_k127_6331732_4 Belongs to the UPF0342 family K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000001716 229.0
HKD2_k127_6331732_5 - - - - 0.000002909 51.0
HKD2_k127_6356653_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K03502 - - 1.8e-224 700.0
HKD2_k127_6356653_1 H( )-stimulated, divalent metal cation uptake system K03322 - - 4.851e-205 645.0
HKD2_k127_6356653_2 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 346.0
HKD2_k127_6356653_3 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 295.0
HKD2_k127_6356653_4 - - - - 0.0000000000000000000000000000000000000000000000000003788 189.0
HKD2_k127_6356653_5 - - - - 0.0000000000000000000000000002148 123.0
HKD2_k127_6356653_6 YolD-like protein - - - 0.00000000000000000000000002484 114.0
HKD2_k127_6356653_7 - - - - 0.0000000002195 64.0
HKD2_k127_6376662_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0 1039.0
HKD2_k127_6376662_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 331.0
HKD2_k127_6376662_2 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000000001245 214.0
HKD2_k127_6380951_0 Acetyl-CoA hydrolase/transferase N-terminal domain K18118 - 2.8.3.18 6.404e-277 857.0
HKD2_k127_6380951_1 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 7.891e-262 811.0
HKD2_k127_6380951_2 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 8.314e-259 811.0
HKD2_k127_6380951_3 Ammonium transporter K03320 - - 4.774e-228 710.0
HKD2_k127_6380951_4 ABC transporter K06147 - - 1.327e-197 627.0
HKD2_k127_6380951_5 transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 467.0
HKD2_k127_6380951_6 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 319.0
HKD2_k127_6380951_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001341 273.0
HKD2_k127_6380951_8 3D domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000341 256.0
HKD2_k127_6380951_9 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000003281 195.0
HKD2_k127_6388343_0 Mate efflux family protein - - - 8.425e-216 677.0
HKD2_k127_6388343_1 type ii restriction enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 556.0
HKD2_k127_6388343_2 Protein of unknown function (DUF1541) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001655 254.0
HKD2_k127_6388343_3 Multi-copper - - - 0.00000000000000000000000000000000000000000000000000000000000000001101 226.0
HKD2_k127_6388343_4 COG1145 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000165 190.0
HKD2_k127_6388343_5 Metal-sensitive transcriptional repressor - - - 0.0000000000000000000000000000000000000000002152 159.0
HKD2_k127_6416884_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 572.0
HKD2_k127_6416884_1 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000000002573 137.0
HKD2_k127_6416884_2 Phosphate-starvation-inducible E K13256 - - 0.00001405 48.0
HKD2_k127_6416884_3 - - - - 0.00002557 46.0
HKD2_k127_6430742_0 ABC transporter, ATP-binding protein - - - 1.1e-320 985.0
HKD2_k127_6430742_1 Oxidoreductase K22230 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114,GO:0102497 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 351.0
HKD2_k127_6430742_2 - - - - 0.000000000000000000002641 96.0
HKD2_k127_6431048_0 Oligoendopeptidase M3 Family - - - 0.0 1026.0
HKD2_k127_6434991_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 7.423e-205 653.0
HKD2_k127_6434991_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 387.0
HKD2_k127_6434991_2 - - - - 0.00002507 46.0
HKD2_k127_6452511_0 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 299.0
HKD2_k127_6452511_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 284.0
HKD2_k127_6452511_2 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009526 270.0
HKD2_k127_6452511_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002799 271.0
HKD2_k127_6452511_4 Belongs to the 'phage' integrase family - - - 0.00008661 46.0
HKD2_k127_6459800_0 Belongs to the peptidase S8 family K13277 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 373.0
HKD2_k127_6459800_1 COG0671 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008203 274.0
HKD2_k127_6459800_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03169 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001716 260.0
HKD2_k127_6459800_3 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000002032 111.0
HKD2_k127_6459800_4 - - - - 0.00007093 47.0
HKD2_k127_6504573_0 Adenine deaminase C-terminal domain K01486 - 3.5.4.2 6.833e-270 835.0
HKD2_k127_6504573_1 Amidohydrolase family K01487 - 3.5.4.3 3.331e-232 724.0
HKD2_k127_6504573_2 xanthine K16169 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - 1.868e-218 683.0
HKD2_k127_6504573_3 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 401.0
HKD2_k127_6504573_5 - - - - 0.00000000000000000000000004776 109.0
HKD2_k127_6506201_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000001411 191.0
HKD2_k127_6506201_2 Archaeal transcriptional regulator TrmB - - - 0.0004875 53.0
HKD2_k127_6506201_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0009163 43.0
HKD2_k127_6515162_0 COG2195 Di- and tripeptidases K01258,K01263 - 3.4.11.14,3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 595.0
HKD2_k127_6515162_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0050896 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 463.0
HKD2_k127_6515162_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 335.0
HKD2_k127_6584772_1 Spore coat protein CotH K06330 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 586.0
HKD2_k127_6584772_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 329.0
HKD2_k127_6584772_3 Lysine methyltransferase K07117 - - 0.0000000000000000000000000000000000000000000000000000005433 194.0
HKD2_k127_6584772_5 Domain of unknown function (DUF4386) - - - 0.0000000004778 65.0
HKD2_k127_6584772_6 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.0001147 45.0
HKD2_k127_6589695_0 Polysaccharide biosynthesis protein K19421 GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192 - 6.43e-293 909.0
HKD2_k127_6589695_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 523.0
HKD2_k127_6589695_2 Glycosyl transferase 4-like K19422 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 516.0
HKD2_k127_6589695_3 Glycosyl transferases group 1 K19424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002025 243.0
HKD2_k127_6589695_4 COG0489 ATPases involved in chromosome partitioning - - - 0.000000000000000000000000000000000000000000000000000000000000000000002674 242.0
HKD2_k127_6589695_5 biosynthesis protein - - - 0.0000000000000000000000000000000000000189 149.0
HKD2_k127_6594001_0 glutamate K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 559.0
HKD2_k127_6594001_1 COG3629 DNA-binding transcriptional activator of the SARP family - - - 0.000000008694 59.0
HKD2_k127_6594001_2 Formiminotransferase-cyclodeaminase - - - 0.00000002273 56.0
HKD2_k127_6619891_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 3.444e-266 823.0
HKD2_k127_6619891_1 transcriptional regulator containing CBS domains - - - 3.343e-253 784.0
HKD2_k127_6619891_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 3.079e-212 662.0
HKD2_k127_6619891_3 COG0618 Exopolyphosphatase-related proteins K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 533.0
HKD2_k127_6619891_4 COG0006 Xaa-Pro aminopeptidase K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 534.0
HKD2_k127_6619891_5 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 366.0
HKD2_k127_6619891_6 Mechanosensitive ion channel K03442,K16052 - - 0.00000000000000000000000000000000000000000000000000000000000001474 220.0
HKD2_k127_6619891_7 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000001543 215.0
HKD2_k127_6619891_8 YtpI-like protein - - - 0.0000000000000000000000000000000000000004868 151.0
HKD2_k127_6619891_9 - - - - 0.0000000000000000001113 90.0
HKD2_k127_6621512_0 Male sterility protein K01710 - 4.2.1.46 6.7e-201 627.0
HKD2_k127_6621512_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 505.0
HKD2_k127_6621512_2 Male sterility protein K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 419.0
HKD2_k127_6621512_3 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 315.0
HKD2_k127_6621512_4 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000008342 192.0
HKD2_k127_6621512_5 Glycosyl transferases group 1 - - - 0.00005441 46.0
HKD2_k127_6625434_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1697.0
HKD2_k127_6625434_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1171.0
HKD2_k127_6625434_2 MMPL domain protein K06994,K07003 - - 0.0 1112.0
HKD2_k127_6625434_3 Putative adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 459.0
HKD2_k127_6625434_4 COG3103 SH3 domain protein K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 370.0
HKD2_k127_6625434_5 Uncharacterized protein conserved in bacteria (DUF2198) - - - 0.000000000000000000000000004723 111.0
HKD2_k127_6625434_6 Belongs to the UPF0312 family - - - 0.000000000000000000008999 92.0
HKD2_k127_6721456_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1817.0
HKD2_k127_6721456_1 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding K06714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 398.0
HKD2_k127_6721456_2 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 0.0000000000000000000000000013 113.0
HKD2_k127_6721456_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000002423 58.0
HKD2_k127_6721456_4 - - - - 0.000002897 49.0
HKD2_k127_6721456_5 N-terminal half of MaoC dehydratase K14449 - 4.2.1.148 0.0001209 45.0
HKD2_k127_6721456_6 AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.0005997 43.0
HKD2_k127_6727437_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002801 252.0
HKD2_k127_6727437_1 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000002253 220.0
HKD2_k127_6727437_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000009363 175.0
HKD2_k127_6738994_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03215 - 2.1.1.190,2.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 510.0
HKD2_k127_6738994_1 drug exporters of the RND superfamily K06994,K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005093 277.0
HKD2_k127_6738994_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000002263 168.0
HKD2_k127_6738994_3 resolvase - - - 0.0000000000000000000000000000000000000002719 153.0
HKD2_k127_6738994_4 Recombinase - - - 0.000000000000000000000000000005272 123.0
HKD2_k127_6764601_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 2.234e-307 948.0
HKD2_k127_6764601_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 278.0
HKD2_k127_6764601_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000000008216 190.0
HKD2_k127_6779090_0 COG1680 Beta-lactamase class C and other penicillin binding proteins K06160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 459.0
HKD2_k127_6779090_1 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 358.0
HKD2_k127_6787180_0 PFAM LysR substrate-binding protein, regulatory protein LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 502.0
HKD2_k127_6787180_1 Cache_2 K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 353.0
HKD2_k127_6787180_2 diguanylate cyclase - - - 0.000000000002945 68.0
HKD2_k127_6787257_0 Major facilitator superfamily K08161 - - 2.707e-220 687.0
HKD2_k127_6787257_1 Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 448.0
HKD2_k127_6807020_0 COG2217 Cation transport ATPase K01534 - 3.6.3.3,3.6.3.5 0.0 1070.0
HKD2_k127_6807020_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 3.675e-195 616.0
HKD2_k127_6807020_2 COG0583 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 512.0
HKD2_k127_6807020_3 protein, homolog of Cu resistance protein CopC K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002391 293.0
HKD2_k127_6807020_4 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.0000000000000000000000000000000000000000000000000183 181.0
HKD2_k127_6807020_5 YhfH-like protein - - - 0.00000000000002978 73.0
HKD2_k127_6807020_6 YhfH-like protein - - - 0.00000000005533 64.0
HKD2_k127_6807020_7 YhfH-like protein - - - 0.0000000002722 62.0
HKD2_k127_6807020_8 - - - - 0.000002897 49.0
HKD2_k127_6807080_0 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 536.0
HKD2_k127_6807080_1 Protein of unknown function (DUF3231) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 286.0
HKD2_k127_6807080_2 - - - - 0.0000000000008461 70.0
HKD2_k127_6812460_0 Major Facilitator Superfamily K08152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007682 290.0
HKD2_k127_6812460_1 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004659 276.0
HKD2_k127_6812460_2 Glycoside Hydrolase Family 18 K01183 - 3.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000003347 246.0
HKD2_k127_6812460_3 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000002462 193.0
HKD2_k127_6812460_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000008679 188.0
HKD2_k127_6812460_5 Protein of unknown function (DUF3934) - - - 0.0000000000000005932 79.0
HKD2_k127_6835472_0 deacetylase K01567 GO:0005575,GO:0016020 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 428.0
HKD2_k127_6835472_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03215 - 2.1.1.190,2.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 283.0
HKD2_k127_6835472_2 - - - - 0.0000000000000000000000000000005866 122.0
HKD2_k127_6835472_3 - - - - 0.0000000000000000000000000002355 117.0
HKD2_k127_6835472_4 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 0.0000000000000001024 80.0
HKD2_k127_6835472_5 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 0.000000000005436 67.0
HKD2_k127_68372_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 8.425e-274 851.0
HKD2_k127_68372_1 Penicillin-binding Protein K12555,K18770 - 2.4.1.129,3.4.16.4 1.269e-236 746.0
HKD2_k127_68372_10 Family of unknown function (DUF5366) - - - 0.000000000000000000000000000000000000000000000000000000000008679 212.0
HKD2_k127_68372_11 Kinase associated protein B K06347 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000003583 164.0
HKD2_k127_68372_13 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000008705 86.0
HKD2_k127_68372_14 - - - - 0.000000000000001015 78.0
HKD2_k127_68372_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 602.0
HKD2_k127_68372_3 FAD-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 520.0
HKD2_k127_68372_4 GTP cyclohydrolase II K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 410.0
HKD2_k127_68372_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 364.0
HKD2_k127_68372_6 Inhibitor of the KinA pathway K06348 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 364.0
HKD2_k127_68372_7 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 359.0
HKD2_k127_68372_8 COG1734 DnaK suppressor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 344.0
HKD2_k127_68372_9 HAD superfamily, subfamily IIIB (Acid phosphatase) K05967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 289.0
HKD2_k127_6845698_0 ABC transporter K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 522.0
HKD2_k127_6845698_1 chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 402.0
HKD2_k127_6845698_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000001519 166.0
HKD2_k127_6846336_0 Pilus assembly protein K18640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 593.0
HKD2_k127_6846336_1 DEAD DEAH box helicase K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 599.0
HKD2_k127_6846336_2 - - - - 0.0000000000000000000000000000000000000000000000000000000004278 206.0
HKD2_k127_6846336_3 Phosphotransferase enzyme family - - - 0.000000000000001256 78.0
HKD2_k127_6846336_4 - - - - 0.000000000003005 66.0
HKD2_k127_6847992_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 8.77e-272 843.0
HKD2_k127_6847992_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00262 - 1.4.1.2,1.4.1.4 3.452e-250 777.0
HKD2_k127_6847992_10 COG2270 Permeases of the major facilitator superfamily K06902 - - 0.0000000000000000000000000000000000000000000000003403 176.0
HKD2_k127_6847992_11 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000000000000037 139.0
HKD2_k127_6847992_12 - - - - 0.00000000007273 68.0
HKD2_k127_6847992_2 Methyltransferase K06969 - 2.1.1.191 1.723e-210 658.0
HKD2_k127_6847992_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 589.0
HKD2_k127_6847992_4 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 461.0
HKD2_k127_6847992_5 Transcriptional regulator K09681 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 429.0
HKD2_k127_6847992_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 375.0
HKD2_k127_6847992_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 350.0
HKD2_k127_6847992_8 Putative threonine/serine exporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 338.0
HKD2_k127_6847992_9 Threonine/Serine exporter, ThrE - - - 0.00000000000000000000000000000000000000000000000002126 182.0
HKD2_k127_6848941_0 Multi-copper - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 436.0
HKD2_k127_6848941_1 P-type ATPase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 374.0
HKD2_k127_6848941_2 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000222 217.0
HKD2_k127_6848941_3 - - - - 0.0000006868 51.0
HKD2_k127_6848941_4 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.000001612 50.0
HKD2_k127_6866582_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1054.0
HKD2_k127_6866582_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 589.0
HKD2_k127_6866582_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 496.0
HKD2_k127_6866582_3 CBS domain - GO:0006355,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0045013,GO:0045892,GO:0045934,GO:0045990,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 342.0
HKD2_k127_6866824_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 525.0
HKD2_k127_6866824_1 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 455.0
HKD2_k127_6866824_2 Domain of unknown function (DUF1905) - - - 0.000000000000000000000000000000000000000003368 156.0
HKD2_k127_6866824_3 - - - - 0.000000000000000000001252 95.0
HKD2_k127_6866824_4 Related to alanyl-tRNA synthetase HxxxH domain K01872 - 6.1.1.7 0.00000002486 56.0
HKD2_k127_6871272_0 Zinc finger, swim domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 349.0
HKD2_k127_6871272_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 302.0
HKD2_k127_6871272_2 TM2 domain - - - 0.00000000000000000000000000008733 119.0
HKD2_k127_6874119_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.428e-249 773.0
HKD2_k127_6874119_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 5.197e-214 668.0
HKD2_k127_6874119_2 Chemotaxis K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 516.0
HKD2_k127_6874119_3 Chemoreceptor zinc-binding domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 512.0
HKD2_k127_6874119_4 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 396.0
HKD2_k127_6874119_5 Belongs to the UPF0340 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 294.0
HKD2_k127_6874119_6 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009914 281.0
HKD2_k127_6874119_7 Nuclease-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004107 287.0
HKD2_k127_6874119_8 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000000000000000000000000000000000000000000000007537 209.0
HKD2_k127_6890397_0 Glutamate-cysteine ligase K01919 - 6.3.2.2 0.0 1143.0
HKD2_k127_6890397_1 Domain of unknown function (DUF4317) - - - 3.391e-215 672.0
HKD2_k127_6890397_10 - - - - 0.00000000000000255 79.0
HKD2_k127_6890397_2 chemotaxis protein K06595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 499.0
HKD2_k127_6890397_3 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 395.0
HKD2_k127_6890397_4 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 387.0
HKD2_k127_6890397_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000013 193.0
HKD2_k127_6890397_6 Sulfurtransferase - - - 0.00000000000000000000000000000000000000000003291 162.0
HKD2_k127_6890397_7 COG3278 Cbb3-type cytochrome oxidase, subunit 1 - - - 0.00000000000000000000000000000000000000009979 154.0
HKD2_k127_6890397_8 MarR family transcriptional regulator - - - 0.0000000000000000000000000000000000000548 144.0
HKD2_k127_6890397_9 Sporulation protein Cse60 - - - 0.0000000000000000000000003444 105.0
HKD2_k127_6890545_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1630.0
HKD2_k127_6890545_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - 0.0 1220.0
HKD2_k127_6890545_10 Belongs to the HesB IscA family - - - 0.0000000000000000000000000000007205 123.0
HKD2_k127_6890545_11 COG4846 Membrane protein involved in cytochrome C biogenesis - - - 0.0000000000000000000000000000008448 123.0
HKD2_k127_6890545_12 - - - - 0.0000000000000000000000019 105.0
HKD2_k127_6890545_13 Small acid-soluble spore protein N family K06431 - - 0.0000000000000000004611 87.0
HKD2_k127_6890545_14 Belongs to the Tlp family K06434 - - 0.0000000000000001375 81.0
HKD2_k127_6890545_15 YycC-like protein - - - 0.000000000004374 66.0
HKD2_k127_6890545_16 Belongs to the SspP family K06433 - - 0.00000000172 60.0
HKD2_k127_6890545_17 - - - - 0.000004127 48.0
HKD2_k127_6890545_18 asexual reproduction K06432 - - 0.0001006 46.0
HKD2_k127_6890545_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 445.0
HKD2_k127_6890545_3 chemotaxis protein K06595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008204 369.0
HKD2_k127_6890545_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003133 280.0
HKD2_k127_6890545_5 thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003113 240.0
HKD2_k127_6890545_6 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000000000001076 232.0
HKD2_k127_6890545_7 Protein of unknown function (DUF2621) - - - 0.0000000000000000000000000000000000000000000000000000000000000001118 223.0
HKD2_k127_6890545_8 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000101 211.0
HKD2_k127_6890545_9 - - - - 0.000000000000000000000000000000000000000000000002443 173.0
HKD2_k127_6915476_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 4.172e-316 973.0
HKD2_k127_6915476_1 protein conserved in bacteria K00243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 489.0
HKD2_k127_6915476_2 Spore Coat K06334 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 361.0
HKD2_k127_6915476_3 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000001291 222.0
HKD2_k127_6915476_4 CotJB protein K06333 - - 0.00000000000000000000000000000000000002748 144.0
HKD2_k127_6915476_5 - - - - 0.0000000000000000000000000000002278 127.0
HKD2_k127_6915476_6 Spore coat associated protein JA (CotJA) K06332 - - 0.000000000000000000000000001247 114.0
HKD2_k127_6963103_0 PFAM Type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 507.0
HKD2_k127_6963103_1 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005522 278.0
HKD2_k127_6963103_2 Thioredoxin - - - 0.00000000000000000000000000000000000000000001038 164.0
HKD2_k127_6963103_3 Pfam:N_methyl_3 K02456,K02650 - - 0.000000000000001506 81.0
HKD2_k127_6963103_4 KR domain - - - 0.00001821 46.0
HKD2_k127_6963103_5 Pilus assembly protein PilX - - - 0.000541 51.0
HKD2_k127_6984638_0 Stage V sporulation protein AF K06408 - - 2.191e-254 791.0
HKD2_k127_6984638_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.055e-250 777.0
HKD2_k127_6984638_10 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane K06384 GO:0005575,GO:0005623,GO:0008150,GO:0010564,GO:0022603,GO:0030428,GO:0032465,GO:0032467,GO:0032954,GO:0042173,GO:0043937,GO:0044087,GO:0044089,GO:0044464,GO:0045595,GO:0045787,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051130,GO:0051302,GO:0051726,GO:0051781,GO:0065007,GO:0090068,GO:1901891,GO:1901893 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 320.0
HKD2_k127_6984638_11 Stage V sporulation protein AA K06403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 301.0
HKD2_k127_6984638_12 Belongs to the Fur family K03711 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 284.0
HKD2_k127_6984638_13 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000552 271.0
HKD2_k127_6984638_14 Stage V sporulation protein AE K06407 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002668 269.0
HKD2_k127_6984638_15 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition K06379 GO:0000003,GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000008004 262.0
HKD2_k127_6984638_16 Stage V sporulation protein AB K06404 - - 0.00000000000000000000000000000000000000000000000000000000001668 209.0
HKD2_k127_6984638_17 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000000000000000000000000000000000000000000114 209.0
HKD2_k127_6984638_18 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.000000000000000000000000000000000000000000000000001462 184.0
HKD2_k127_6984638_19 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K02859 - - 0.0000000000000000000000000000000000000000000000007124 179.0
HKD2_k127_6984638_2 phosphorylase K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 1.005e-224 702.0
HKD2_k127_6984638_20 Protein of unknown function (DUF4227) - - - 0.0000000000000000000000000000000005274 132.0
HKD2_k127_6984638_21 DNA helicase - - - 0.0000000000000000000000000007403 113.0
HKD2_k127_6984638_3 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 5.4.2.7 6.947e-215 671.0
HKD2_k127_6984638_4 Belongs to the peptidase S11 family K07258 GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 1.759e-202 635.0
HKD2_k127_6984638_5 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 522.0
HKD2_k127_6984638_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 458.0
HKD2_k127_6984638_7 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 452.0
HKD2_k127_6984638_8 Secreted protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 428.0
HKD2_k127_6984638_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 405.0
HKD2_k127_6986579_0 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes K05592 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 5.069e-215 677.0
HKD2_k127_6986579_1 nitric oxide dioxygenase activity K00523,K00528,K02574,K07098 - 1.17.1.1,1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 553.0
HKD2_k127_6986579_2 Phosphomethylpyrimidine kinase K00868 - 2.7.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 531.0
HKD2_k127_6986579_3 ECF-type riboflavin transporter, S component - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 314.0
HKD2_k127_6986579_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001209 278.0
HKD2_k127_6986579_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000001757 184.0
HKD2_k127_6986579_6 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000007068 163.0
HKD2_k127_6986579_7 Prolyl oligopeptidase family - - - 0.00000000000029 69.0
HKD2_k127_7015796_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 2.245e-274 846.0
HKD2_k127_7015796_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 7.381e-261 807.0
HKD2_k127_7015796_10 Belongs to the nlpA lipoprotein family K02073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 488.0
HKD2_k127_7015796_11 NLPA lipoprotein K02073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 436.0
HKD2_k127_7015796_12 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 359.0
HKD2_k127_7015796_13 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 358.0
HKD2_k127_7015796_14 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K07533 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 338.0
HKD2_k127_7015796_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 317.0
HKD2_k127_7015796_16 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007908 277.0
HKD2_k127_7015796_17 SMART extracellular solute-binding protein family 3 K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006009 268.0
HKD2_k127_7015796_18 ABC transporter permease K02072 - - 0.000000000000000000000000000000000000000000000000000000000000000001523 233.0
HKD2_k127_7015796_19 membrane - - - 0.0000000000000000000000000000000000000000000229 164.0
HKD2_k127_7015796_2 COG0025 NhaP-type Na H and K H antiporters K03316 GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 - 4.859e-236 749.0
HKD2_k127_7015796_20 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000005548 167.0
HKD2_k127_7015796_21 COG0695 Glutaredoxin and related proteins - - - 0.0000000000000000000000000000000001005 133.0
HKD2_k127_7015796_22 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000004616 96.0
HKD2_k127_7015796_23 - - - - 0.00000000000001209 77.0
HKD2_k127_7015796_24 YtkA-like - - - 0.00000000000007598 78.0
HKD2_k127_7015796_3 Sodium:sulfate symporter transmembrane region K03319 - - 1.283e-213 674.0
HKD2_k127_7015796_4 acyl-CoA dehydrogenase - - - 9.652e-201 631.0
HKD2_k127_7015796_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 2.062e-195 619.0
HKD2_k127_7015796_6 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 612.0
HKD2_k127_7015796_7 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system K02071 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 606.0
HKD2_k127_7015796_8 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase K01436,K21613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 604.0
HKD2_k127_7015796_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 559.0
HKD2_k127_7042295_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 3.6e-264 815.0
HKD2_k127_7042295_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 8.895e-203 635.0
HKD2_k127_7042295_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 496.0
HKD2_k127_7042295_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 411.0
HKD2_k127_7042295_4 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008644 370.0
HKD2_k127_7042295_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000001149 235.0
HKD2_k127_7042295_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000003906 147.0
HKD2_k127_7042295_7 NETI protein - - - 0.00000000000000000000003226 100.0
HKD2_k127_7072867_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 308.0
HKD2_k127_7072867_1 GNAT family acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006807 263.0
HKD2_k127_7072867_2 Psort location Cytoplasmic, score - - - 0.0000000001514 64.0
HKD2_k127_7080618_0 Initiates the rapid degradation of small, acid-soluble proteins during spore germination K06012 GO:0000003,GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019954,GO:0030436,GO:0032502,GO:0043170,GO:0043934,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.24.78 3.711e-195 613.0
HKD2_k127_7080618_1 stage II sporulation protein P K06385 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 533.0
HKD2_k127_7080618_2 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008006 524.0
HKD2_k127_7080618_3 Competence protein ComEC K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 519.0
HKD2_k127_7080618_4 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000000000000538 126.0
HKD2_k127_7080618_6 - - - - 0.0000001525 54.0
HKD2_k127_7080618_7 Protein of unknown function (DUF3679) - - - 0.0001133 44.0
HKD2_k127_7080640_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1193.0
HKD2_k127_7080640_1 glutamine synthetase K01915 GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141 6.3.1.2 1.427e-274 847.0
HKD2_k127_7080640_10 Cell division suppressor protein YneA - GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.0000000000000000000000000000009574 124.0
HKD2_k127_7080640_11 UPF0291 protein - - - 0.000000000000000000000000224 110.0
HKD2_k127_7080640_12 COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance - GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - 0.00000000000000000000008714 97.0
HKD2_k127_7080640_13 COG4846 Membrane protein involved in cytochrome C biogenesis - - - 0.00000000000000000004218 91.0
HKD2_k127_7080640_14 - - - - 0.0000000000000000118 84.0
HKD2_k127_7080640_15 Belongs to the 'phage' integrase family - - - 0.00000000009996 62.0
HKD2_k127_7080640_2 Threonine synthase K01733 - 4.2.3.1 2.091e-254 792.0
HKD2_k127_7080640_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 370.0
HKD2_k127_7080640_4 cytochrome c biogenesis protein K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 363.0
HKD2_k127_7080640_5 resolvase - GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 334.0
HKD2_k127_7080640_6 transcriptional K03713,K15580 GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000002852 219.0
HKD2_k127_7080640_7 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000025 209.0
HKD2_k127_7080640_8 Sporulation inhibitor of replication protein sirA - - - 0.00000000000000000000000000000000000000000000000000000002707 199.0
HKD2_k127_7080640_9 UPF0154 protein K09976 - - 0.0000000000000000000000000000008681 122.0
HKD2_k127_7093070_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 6.508e-249 769.0
HKD2_k127_7093070_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 1.444e-196 616.0
HKD2_k127_7093070_10 Protein of unknown function (DUF3792) - - - 0.000000000000000000000000000000000000000000001453 169.0
HKD2_k127_7093070_12 Preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000000007154 132.0
HKD2_k127_7093070_13 Protein of unknown function (DUF2905) - - - 0.0000000000000000000002902 97.0
HKD2_k127_7093070_14 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000138 67.0
HKD2_k127_7093070_16 - - - - 0.00005403 47.0
HKD2_k127_7093070_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 602.0
HKD2_k127_7093070_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 595.0
HKD2_k127_7093070_4 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 445.0
HKD2_k127_7093070_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 339.0
HKD2_k127_7093070_6 choline kinase involved in LPS biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 317.0
HKD2_k127_7093070_7 Nuclease-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003396 276.0
HKD2_k127_7093070_8 spore coat assembly protein SafA K06370 GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117 - 0.00000000000000000000000000000000000000000000000000000006519 217.0
HKD2_k127_7093070_9 BofC C-terminal domain K06318 - - 0.000000000000000000000000000000000000000000000001986 178.0
HKD2_k127_7112374_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - 5.34e-244 761.0
HKD2_k127_7112374_1 Histidine kinase - - - 8.211e-224 706.0
HKD2_k127_7112374_10 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007148 265.0
HKD2_k127_7112374_11 COG0590 Cytosine adenosine deaminases K01487 GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000005258 257.0
HKD2_k127_7112374_12 COG0517 FOG CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000009355 213.0
HKD2_k127_7112374_13 transcriptional - GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000009873 184.0
HKD2_k127_7112374_14 Rhodanese domain protein - - - 0.000000000000000000000000000000000000000006369 158.0
HKD2_k127_7112374_15 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000001062 152.0
HKD2_k127_7112374_16 - - - - 0.0000000000000000000000000000000000000007883 152.0
HKD2_k127_7112374_17 Protein of unknown function (DUF1694) - - - 0.000000000000000000000000000000000000008512 149.0
HKD2_k127_7112374_18 Belongs to the UPF0180 family - - - 0.0000000000000000000000000000003114 124.0
HKD2_k127_7112374_19 redox protein, regulator of disulfide bond formation - - - 0.000000000001381 69.0
HKD2_k127_7112374_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 2.795e-199 628.0
HKD2_k127_7112374_21 Competence transcription factor K02250 - - 0.000006324 55.0
HKD2_k127_7112374_3 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 3.549e-196 615.0
HKD2_k127_7112374_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 610.0
HKD2_k127_7112374_5 Glycosyl transferase group 1 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 517.0
HKD2_k127_7112374_6 Mg2 transporter protein CorA family protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 508.0
HKD2_k127_7112374_7 6-phosphogluconolactonase K07404 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 445.0
HKD2_k127_7112374_8 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 284.0
HKD2_k127_7112374_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001133 275.0
HKD2_k127_7113101_0 COG1132 ABC-type multidrug transport system, ATPase and permease components K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 287.0
HKD2_k127_7113101_1 COG0489 ATPases involved in chromosome partitioning K00903 - 2.7.10.2 0.00000000000000000000000000000000000000000000000000000000000000000000959 240.0
HKD2_k127_7113101_2 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000003584 208.0
HKD2_k127_7113101_3 biosynthesis protein - - - 0.000000000000000000000000000000000000000000000009946 179.0
HKD2_k127_7118226_0 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007562 257.0
HKD2_k127_7118226_1 Transglycosylase - - - 0.00000000000000000000000000004621 118.0
HKD2_k127_7146706_0 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01034 - 2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 383.0
HKD2_k127_7146706_1 AmiS/UreI family transporter K22112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 346.0
HKD2_k127_7146706_3 Alkylphosphonate utilization operon protein PhnA K06193 - - 0.000000000000000000000000000000000000000000000000000000000000004295 217.0
HKD2_k127_7146706_4 - - - - 0.0000000000000000000000000000000000000000000000002316 180.0
HKD2_k127_7146706_5 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K11535 - - 0.00000000000000000000000005489 107.0
HKD2_k127_7146706_6 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01035 - 2.8.3.8,2.8.3.9 0.00000000000003887 72.0
HKD2_k127_7150724_0 stage III sporulation protein AE K06394 - - 9.061e-199 625.0
HKD2_k127_7150724_1 COG0006 Xaa-Pro aminopeptidase K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 594.0
HKD2_k127_7150724_10 Conserved membrane protein YqhR - - - 0.0000000000000000000000000000000000000000000000000000597 191.0
HKD2_k127_7150724_11 - - - - 0.00000000000000000000000000000003021 130.0
HKD2_k127_7150724_12 Stage III sporulation protein AF (Spore_III_AF) K06395 - - 0.00000000000000000000001044 102.0
HKD2_k127_7150724_14 - - - - 0.0003443 44.0
HKD2_k127_7150724_15 - K06392 - - 0.0003851 45.0
HKD2_k127_7150724_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 529.0
HKD2_k127_7150724_3 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009791 516.0
HKD2_k127_7150724_4 stage III sporulation protein AA K06390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 447.0
HKD2_k127_7150724_5 esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 439.0
HKD2_k127_7150724_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 327.0
HKD2_k127_7150724_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000001953 234.0
HKD2_k127_7150724_8 Stage III sporulation protein AB (spore_III_AB) K06391 - - 0.0000000000000000000000000000000000000000000000000000000000002221 215.0
HKD2_k127_7150724_9 Stage III sporulation protein AD K06393 - - 0.00000000000000000000000000000000000000000000000000000002164 199.0
HKD2_k127_717421_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0 1426.0
HKD2_k127_717421_1 Signal transduction histidine kinase K07636 - 2.7.13.3 5.009e-227 717.0
HKD2_k127_717421_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016491,GO:0016620,GO:0016903,GO:0019318,GO:0019319,GO:0036094,GO:0043891,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 599.0
HKD2_k127_717421_3 Uncharacterised MFS-type transporter YbfB K05548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 593.0
HKD2_k127_717421_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 478.0
HKD2_k127_717421_5 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 292.0
HKD2_k127_717421_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004885 277.0
HKD2_k127_717421_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.00000000000000000000000000000003499 125.0
HKD2_k127_717421_8 - - - - 0.000005871 52.0
HKD2_k127_7191600_0 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 507.0
HKD2_k127_7191600_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 401.0
HKD2_k127_7191600_2 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 371.0
HKD2_k127_7191600_3 protein conserved in bacteria K09770 - - 0.000000000000000000000000000000000000000000000000000000000000809 212.0
HKD2_k127_7191600_4 flagellar protein FliS K02422 - - 0.00000000000000000000000000000000000000000000000003051 182.0
HKD2_k127_7191600_5 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.00000000000000000000000000000000000000000000000004554 182.0
HKD2_k127_7191600_6 flagellar protein FlaG K06603 - - 0.00000000000000000000000000000000003538 138.0
HKD2_k127_7191600_7 FlhB HrpN YscU SpaS Family K04061 - - 0.00000000000000000000000000000006293 126.0
HKD2_k127_7191600_8 - - - - 0.0000000000000000001223 90.0
HKD2_k127_7191600_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000005275 54.0
HKD2_k127_7203937_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1250.0
HKD2_k127_7203937_1 Belongs to the LTA synthase family K19005 GO:0005575,GO:0005576 2.7.8.20 0.0 1005.0
HKD2_k127_7203937_10 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 402.0
HKD2_k127_7203937_11 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07693 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 341.0
HKD2_k127_7203937_12 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 342.0
HKD2_k127_7203937_13 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 338.0
HKD2_k127_7203937_14 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 325.0
HKD2_k127_7203937_15 Methyltransferase K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 299.0
HKD2_k127_7203937_16 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 298.0
HKD2_k127_7203937_17 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008848 258.0
HKD2_k127_7203937_18 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000002969 227.0
HKD2_k127_7203937_19 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system K02071 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000002375 211.0
HKD2_k127_7203937_2 acyl-CoA dehydrogenase K00248 - 1.3.8.1 6.578e-316 974.0
HKD2_k127_7203937_20 Belongs to the ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000004864 205.0
HKD2_k127_7203937_21 NosL K19342 - - 0.000000000000000000000000000000000000000000000000000000006925 203.0
HKD2_k127_7203937_22 COG1658 Small primase-like proteins (Toprim domain) K07476 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000007626 164.0
HKD2_k127_7203937_23 Thioredoxin - GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000000001603 151.0
HKD2_k127_7203937_24 Coat F domain - - - 0.0000000000000000000000000000000000000002165 152.0
HKD2_k127_7203937_25 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) - - - 0.00000000000000000000000000000000003617 140.0
HKD2_k127_7203937_26 Protein of unknown function (DUF1641) - - - 0.0000000000000000000000000000000002868 132.0
HKD2_k127_7203937_27 - - - - 0.00000000000000000000000000002707 119.0
HKD2_k127_7203937_28 Protein of unknown function (DUF1450) - - - 0.000000000000000000002526 96.0
HKD2_k127_7203937_3 O-acetylhomoserine K01740 - 2.5.1.49 7.358e-235 732.0
HKD2_k127_7203937_30 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000006558 49.0
HKD2_k127_7203937_32 - - - - 0.0002699 44.0
HKD2_k127_7203937_4 Belongs to the thiolase family K00632 - 2.3.1.16 2.906e-219 683.0
HKD2_k127_7203937_5 NADH dehydrogenase K03885 - 1.6.99.3 5.431e-213 665.0
HKD2_k127_7203937_6 Belongs to the SEDS family K05837 - - 7.663e-206 644.0
HKD2_k127_7203937_7 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 545.0
HKD2_k127_7203937_8 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008053 490.0
HKD2_k127_7203937_9 Histidine kinase K07778 GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 463.0
HKD2_k127_7219360_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.479e-245 761.0
HKD2_k127_7219360_1 TATA-box binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004632 254.0
HKD2_k127_7219360_2 Stage II sporulation protein D K06381 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000003849 188.0
HKD2_k127_7219360_3 membrane - - - 0.0000000000000000000000000000004073 123.0
HKD2_k127_7236030_0 DNA helicase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 505.0
HKD2_k127_7236030_1 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 423.0
HKD2_k127_7236030_2 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 288.0
HKD2_k127_7245372_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 0.0 1169.0
HKD2_k127_7245372_1 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 412.0
HKD2_k127_7245372_2 - - - - 0.00000000000000001685 82.0
HKD2_k127_7245372_3 - - - - 0.0000000001587 63.0
HKD2_k127_7248047_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1133.0
HKD2_k127_7248047_1 Heat shock 70 kDa protein K04043 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - 0.0 1091.0
HKD2_k127_7248047_10 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000002747 61.0
HKD2_k127_7248047_11 protein containing a divergent version of the methyl-accepting chemotaxis-like domain - - - 0.00000006228 54.0
HKD2_k127_7248047_12 - - - - 0.0000001897 53.0
HKD2_k127_7248047_2 ribosomal protein S12 methylthiotransferase K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 4.889e-228 709.0
HKD2_k127_7248047_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 5.608e-207 647.0
HKD2_k127_7248047_4 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 564.0
HKD2_k127_7248047_5 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 547.0
HKD2_k127_7248047_6 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 537.0
HKD2_k127_7248047_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 383.0
HKD2_k127_7248047_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008544 265.0
HKD2_k127_7248047_9 Protein of unknown function (DUF3679) - - - 0.0000000000000000000000000000000000000000008273 158.0
HKD2_k127_7255361_0 5'3' exonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 505.0
HKD2_k127_7255361_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 366.0
HKD2_k127_7255361_2 COG0328 Ribonuclease HI K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 309.0
HKD2_k127_7255361_3 Transcriptional regulator K13771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001643 253.0
HKD2_k127_7255361_4 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000585 204.0
HKD2_k127_7255361_5 - - - - 0.00000000000000000000000000000000009748 134.0
HKD2_k127_7255361_6 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000006259 88.0
HKD2_k127_7255361_7 Zinc-finger - - - 0.00000000000000005406 82.0
HKD2_k127_7255361_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000004122 62.0
HKD2_k127_7255361_9 Protein of unknown function with HXXEE motif - - - 0.00000122 57.0
HKD2_k127_7255664_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 2.233e-256 797.0
HKD2_k127_7255664_1 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase K03429 - 2.4.1.315 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 534.0
HKD2_k127_7255664_2 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 511.0
HKD2_k127_7255664_3 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 409.0
HKD2_k127_7255664_4 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 329.0
HKD2_k127_7255664_5 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003911 267.0
HKD2_k127_7255664_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000005866 239.0
HKD2_k127_7255664_7 protein conserved in bacteria K09775 - - 0.00000000000000000000000000000000000000000000000000000000000000000002391 235.0
HKD2_k127_7255664_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000001474 188.0
HKD2_k127_7275888_0 COG0247 Fe-S oxidoreductase - - - 0.0 1242.0
HKD2_k127_7275888_1 penicillin-binding protein K21464 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 0.0 1052.0
HKD2_k127_7275888_10 YwhD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 285.0
HKD2_k127_7275888_11 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000003955 213.0
HKD2_k127_7275888_12 COG1078 HD superfamily phosphohydrolases K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000001049 171.0
HKD2_k127_7275888_13 4-oxalocrotonate tautomerase K01821 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 0.000000000000000000000001901 106.0
HKD2_k127_7275888_14 - - - - 0.000002905 53.0
HKD2_k127_7275888_2 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 2.5e-323 993.0
HKD2_k127_7275888_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 1.717e-214 671.0
HKD2_k127_7275888_4 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 566.0
HKD2_k127_7275888_5 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 508.0
HKD2_k127_7275888_6 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 486.0
HKD2_k127_7275888_7 Belongs to the phospholipase D family. Cardiolipin synthase subfamily K06131 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 487.0
HKD2_k127_7275888_8 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 310.0
HKD2_k127_7275888_9 - K09388 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008817 297.0
HKD2_k127_7298860_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 0.0 1090.0
HKD2_k127_7298860_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 4.727e-315 970.0
HKD2_k127_7309107_0 stage V sporulation protein D K08384 - - 0.0 1056.0
HKD2_k127_7309107_1 Penicillin-binding Protein K08724,K12552,K12556 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 290.0
HKD2_k127_7309256_0 Major facilitator superfamily K08177 - - 1.499e-194 612.0
HKD2_k127_7309256_1 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 332.0
HKD2_k127_7309256_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000000000000000000000004722 128.0
HKD2_k127_7309256_3 Fusaric acid resistance protein-like - - - 0.0000000000006303 70.0
HKD2_k127_7309256_4 Fusaric acid resistance protein-like - - - 0.00000001414 59.0
HKD2_k127_7311916_0 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 369.0
HKD2_k127_7311916_1 transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 327.0
HKD2_k127_7311916_2 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002911 277.0
HKD2_k127_7341143_0 Amidohydrolase family K01465,K01466 - 3.5.2.3,3.5.2.5 1.942e-275 852.0
HKD2_k127_7341143_1 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate K01612,K03182,K16874 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61,4.1.1.98 8.675e-219 685.0
HKD2_k127_7341143_10 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000002902 61.0
HKD2_k127_7341143_11 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K00087,K03518 - 1.17.1.4,1.2.5.3 0.0000005513 51.0
HKD2_k127_7341143_2 Isochorismatase family K09020 - 3.5.1.110 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 347.0
HKD2_k127_7341143_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 309.0
HKD2_k127_7341143_4 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.00000000000000000000000000000000000000000000006676 169.0
HKD2_k127_7341143_5 - - - - 0.0000000000000000000000000000000000000000000001355 180.0
HKD2_k127_7341143_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine - - - 0.00000000000000000000000000000000000001388 153.0
HKD2_k127_7341143_7 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.00000000000000000000000000000000003322 136.0
HKD2_k127_7341143_8 BMC - - - 0.00000000000000000000000000000003545 128.0
HKD2_k127_7341143_9 BMC domain - - - 0.0000000000000000000000000000001501 124.0
HKD2_k127_7369370_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - 0.0 1450.0
HKD2_k127_7369370_1 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K10854 - 6.4.1.6 0.0 1441.0
HKD2_k127_7369370_10 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 587.0
HKD2_k127_7369370_11 Stage V sporulation protein AD K06406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 561.0
HKD2_k127_7369370_12 Bacillus/Clostridium GerA spore germination protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 546.0
HKD2_k127_7369370_13 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 532.0
HKD2_k127_7369370_14 Xanthine uracil - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 524.0
HKD2_k127_7369370_15 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 501.0
HKD2_k127_7369370_16 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 498.0
HKD2_k127_7369370_17 Belongs to the UPF0736 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 477.0
HKD2_k127_7369370_18 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 437.0
HKD2_k127_7369370_19 COG2382 Enterochelin esterase and related enzymes K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 433.0
HKD2_k127_7369370_2 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01473,K10855 - 3.5.2.14,6.4.1.6 0.0 1320.0
HKD2_k127_7369370_20 Competence protein K06198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 438.0
HKD2_k127_7369370_21 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP K01090,K01525 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.16,3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 424.0
HKD2_k127_7369370_22 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 426.0
HKD2_k127_7369370_23 Spore germination protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 405.0
HKD2_k127_7369370_24 Spore germination B3/ GerAC like, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 404.0
HKD2_k127_7369370_25 Spore germination B3/ GerAC like, C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 401.0
HKD2_k127_7369370_26 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC K16511 GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 357.0
HKD2_k127_7369370_27 GTP pyrophosphokinase K07816 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 346.0
HKD2_k127_7369370_28 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 304.0
HKD2_k127_7369370_29 Acetone carboxylase gamma subunit K10856 - 6.4.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 291.0
HKD2_k127_7369370_3 DNA helicase K03657 - 3.6.4.12 0.0 1163.0
HKD2_k127_7369370_30 Zn-dependent protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 294.0
HKD2_k127_7369370_31 COG2346 Truncated hemoglobins K06886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003904 259.0
HKD2_k127_7369370_32 COG1267 Phosphatidylglycerophosphatase A and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001832 260.0
HKD2_k127_7369370_33 stage V sporulation protein AC K06405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006879 254.0
HKD2_k127_7369370_34 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress K16509 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001657 242.0
HKD2_k127_7369370_35 Belongs to the 2H phosphoesterase superfamily. YjcG family - - - 0.000000000000000000000000000000000000000000000000000000000000000001106 231.0
HKD2_k127_7369370_36 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000000000000000000000000000003751 231.0
HKD2_k127_7369370_37 stage V sporulation protein K06407 - - 0.0000000000000000000000000000000000000000000000000000000000000002753 221.0
HKD2_k127_7369370_38 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000003496 221.0
HKD2_k127_7369370_39 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000004427 213.0
HKD2_k127_7369370_4 oligoendopeptidase F K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0 1037.0
HKD2_k127_7369370_40 Spore Coat Protein X and V domain K06342 - - 0.00000000000000000000000000000000000000000000000000000000001071 210.0
HKD2_k127_7369370_41 Bacterial transcriptional repressor C-terminal - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000009271 192.0
HKD2_k127_7369370_42 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) - - - 0.0000000000000000000000000000000000000000000000001281 181.0
HKD2_k127_7369370_43 Protein of unknown function (DUF1360) - - - 0.000000000000000000000000000000000000000005605 157.0
HKD2_k127_7369370_44 Stage VI sporulation protein F - - - 0.000000000000000000000000000000000000605 140.0
HKD2_k127_7369370_45 FR47-like protein - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - 0.0000000000000000000000000000000000006271 143.0
HKD2_k127_7369370_46 - - - - 0.000000000000000000000000000000000001595 148.0
HKD2_k127_7369370_47 NAD(P)H-dependent FMN reductase - - - 0.00000000000000000000000000001951 117.0
HKD2_k127_7369370_48 ComZ K02254 - - 0.000000000000000000000005691 102.0
HKD2_k127_7369370_49 - - - - 0.00000000000000000004149 92.0
HKD2_k127_7369370_5 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 2.492e-305 941.0
HKD2_k127_7369370_50 - - - - 0.000000000000000008302 91.0
HKD2_k127_7369370_54 - - - - 0.00000000004021 70.0
HKD2_k127_7369370_55 Protein of unknown function (Tiny_TM_bacill) - - - 0.0000000003053 61.0
HKD2_k127_7369370_56 - - - - 0.0000000174 56.0
HKD2_k127_7369370_57 - - - - 0.0000002827 57.0
HKD2_k127_7369370_59 - - - - 0.00000189 50.0
HKD2_k127_7369370_6 COG3284 Transcriptional activator of acetoin glycerol metabolism K21405 - - 8.433e-271 848.0
HKD2_k127_7369370_60 - - - - 0.000002807 51.0
HKD2_k127_7369370_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 1.363e-234 729.0
HKD2_k127_7369370_8 Acts as a magnesium transporter K06213 - - 3.556e-211 664.0
HKD2_k127_7369370_9 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 587.0
HKD2_k127_7402024_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10548 - 3.6.3.17 4.341e-279 863.0
HKD2_k127_7402024_1 Branched-chain amino acid transport system / permease component K10544,K10547 - - 9.43e-209 653.0
HKD2_k127_7402024_2 Periplasmic binding protein domain K10543,K10546 - - 1.539e-198 622.0
HKD2_k127_7402024_3 Mycoplasma MFS transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 287.0
HKD2_k127_7402024_4 Periplasmic binding protein LacI transcriptional regulator K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001335 265.0
HKD2_k127_7443468_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.166e-257 796.0
HKD2_k127_7443468_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 1.774e-194 610.0
HKD2_k127_7443468_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 388.0
HKD2_k127_7443468_3 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 347.0
HKD2_k127_7443468_4 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000003313 268.0
HKD2_k127_7443468_5 fructose-1,6-bisphosphatase K02446 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000005881 238.0
HKD2_k127_7443468_6 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000000001816 144.0
HKD2_k127_746923_0 Superoxide dismutase K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 407.0
HKD2_k127_746923_1 Protein of unknown function (DUF3907) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008491 274.0
HKD2_k127_746923_2 Belongs to the peptidase S11 family K07258 GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001788 271.0
HKD2_k127_746923_3 - - - - 0.000000002131 61.0
HKD2_k127_7479561_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 3.423e-200 632.0
HKD2_k127_7479561_1 succinate dehydrogenase K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 329.0
HKD2_k127_7479561_2 succinate dehydrogenase K00239 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000001986 206.0
HKD2_k127_7479561_3 Protein of unknown function (DUF2507) - - - 0.00000000000000000000000000000000000000000000000000000001011 201.0
HKD2_k127_7489760_0 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 441.0
HKD2_k127_7489760_1 Protein of unknown function (DUF1700) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004365 267.0
HKD2_k127_7489760_2 Putative adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000003544 237.0
HKD2_k127_7489760_3 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000385 220.0
HKD2_k127_7489760_4 PadR family transcriptional regulator K10947 - - 0.0000000000000000000000000000000000000000000000000000000001162 205.0
HKD2_k127_7489760_5 GDYXXLXY protein - - - 0.00000000000000000000000000000000000000003131 158.0
HKD2_k127_7489760_7 - - - - 0.000000008071 56.0
HKD2_k127_7506045_0 G5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 537.0
HKD2_k127_7506045_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07668 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000002543 185.0
HKD2_k127_7513664_0 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000001611 104.0
HKD2_k127_7514384_0 STAS domain K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006068 272.0
HKD2_k127_7514384_1 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000000004821 190.0
HKD2_k127_7514384_2 IclR helix-turn-helix domain - - - 0.00000000000785 66.0
HKD2_k127_7516004_0 AAA domain - - - 0.0 1160.0
HKD2_k127_7516004_1 Spore photoproduct lyase K03716 GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0005575,GO:0005623,GO:0016829,GO:0016830,GO:0042601,GO:0042763,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070283,GO:0140097 4.1.99.14 1.319e-213 666.0
HKD2_k127_7516004_2 chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000004474 232.0
HKD2_k127_7516004_3 Spore germination protein gerPA/gerPF - - - 0.0000000000000000000000000000000002141 133.0
HKD2_k127_7516004_4 Transcriptional regulator protein (SplA) K06315 - - 0.000000000000000000000000000001926 122.0
HKD2_k127_7516004_5 Spore germination protein gerPA/gerPF - - - 0.000000000000000000000000000002245 121.0
HKD2_k127_7516004_6 dehydratase K17865 - 4.2.1.55 0.000000000000007002 79.0
HKD2_k127_7516004_7 Spore germination protein gerPA/gerPF - - - 0.000001069 53.0
HKD2_k127_7518238_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 518.0
HKD2_k127_7518238_1 Histidine kinase K07681,K11617 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 481.0
HKD2_k127_7518238_2 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07694,K11618 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 287.0
HKD2_k127_7518238_3 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.0000000000000000000000000000000000000000000000000000000000000000008051 232.0
HKD2_k127_7518238_4 2TM domain - - - 0.00000000000000000000000000003526 117.0
HKD2_k127_7519163_0 COG0477 Permeases of the major facilitator superfamily - - - 8.547e-203 638.0
HKD2_k127_7519163_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 483.0
HKD2_k127_7519163_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 408.0
HKD2_k127_7519163_3 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 299.0
HKD2_k127_7519163_4 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000005192 238.0
HKD2_k127_7519163_5 YugN-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003709 231.0
HKD2_k127_7519163_6 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000000005127 116.0
HKD2_k127_7519163_7 YppF-like protein - - - 0.00000000000000000000003152 100.0
HKD2_k127_7519163_8 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.000000000000002108 79.0
HKD2_k127_7519163_9 Serine hydrolase (FSH1) K03928 - 3.1.1.1 0.00000000001161 66.0
HKD2_k127_7524494_0 PQQ enzyme repeat - - - 0.0 1482.0
HKD2_k127_7524494_1 Belongs to the pirin family - - - 5.863e-213 662.0
HKD2_k127_7524494_10 - - - - 0.000005384 49.0
HKD2_k127_7524494_2 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 502.0
HKD2_k127_7524494_3 Sensor_kinase_SpoOB-type, alpha-helical domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 456.0
HKD2_k127_7524494_4 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 424.0
HKD2_k127_7524494_5 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress K16509 - - 0.000000000000000000000000000000000000000000000000000000006919 200.0
HKD2_k127_7524494_6 - - - - 0.00000000000000000000000003491 108.0
HKD2_k127_7524494_7 Belongs to the peptidase S8 family K01361 - 3.4.21.96 0.000000000000000000001276 97.0
HKD2_k127_7524494_9 cellulase activity K01181,K01185,K02027,K07273,K07451,K17315,K17318 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.17,3.2.1.8 0.00000006915 55.0
HKD2_k127_7531075_0 Belongs to the peptidase S8 family K01361,K08652,K14647 - 3.4.21.110,3.4.21.96 0.0 1008.0
HKD2_k127_7531075_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.974e-302 930.0
HKD2_k127_7531075_10 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000000000000000000000001979 111.0
HKD2_k127_7531075_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.526e-276 852.0
HKD2_k127_7531075_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 473.0
HKD2_k127_7531075_4 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 374.0
HKD2_k127_7531075_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001091 272.0
HKD2_k127_7531075_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002972 253.0
HKD2_k127_7531075_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000003208 193.0
HKD2_k127_7531075_8 ATP synthase K02116 - - 0.00000000000000000000000000000000000000005117 154.0
HKD2_k127_7531075_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000001802 121.0
HKD2_k127_7535258_0 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000002682 218.0
HKD2_k127_7535258_1 Low molecular weight phosphatase family - - - 0.00000000000000000000000000000000000000000000000009508 179.0
HKD2_k127_7535258_2 MerR family transcriptional regulator - - - 0.0000000000000000000000000000000000002909 145.0
HKD2_k127_7535258_3 - - - - 0.0000000000000005078 79.0
HKD2_k127_7535258_4 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000001654 64.0
HKD2_k127_7535258_5 Serine hydrolase (FSH1) K03928 - 3.1.1.1 0.00000000565 57.0
HKD2_k127_7547312_0 COG2217 Cation transport ATPase K01534 - 3.6.3.3,3.6.3.5 1.154e-314 973.0
HKD2_k127_7547312_1 Belongs to the UPF0761 family K07058 - - 0.0000000006125 60.0
HKD2_k127_7561_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1426.0
HKD2_k127_7561_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 0.0 1153.0
HKD2_k127_7561_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 469.0
HKD2_k127_7561_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000003873 149.0
HKD2_k127_7561_4 Domain of unknown function (DUF370) - - - 0.00000000000000000000000009 108.0
HKD2_k127_7604851_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 531.0
HKD2_k127_7604851_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 486.0
HKD2_k127_7604851_10 - - - - 0.000000000000000000000000000000000003242 138.0
HKD2_k127_7604851_12 - - - - 0.000000000000000000000001654 106.0
HKD2_k127_7604851_13 - - - - 0.0000000003744 61.0
HKD2_k127_7604851_2 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 461.0
HKD2_k127_7604851_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 396.0
HKD2_k127_7604851_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 347.0
HKD2_k127_7604851_5 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001844 259.0
HKD2_k127_7604851_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002657 248.0
HKD2_k127_7604851_7 Transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000248 234.0
HKD2_k127_7604851_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000006823 213.0
HKD2_k127_7604851_9 - - - - 0.0000000000000000000000000000000000000000000003152 170.0
HKD2_k127_7627580_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1007.0
HKD2_k127_7627580_1 COG1657 Squalene cyclase K18115 - 4.2.1.137 5.386e-279 869.0
HKD2_k127_7627580_2 Protein of unknown function (DUF2515) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 499.0
HKD2_k127_7627580_3 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 334.0
HKD2_k127_7627580_4 Belongs to the arginase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 319.0
HKD2_k127_7627580_5 - - - - 0.0000000000000000000000000000000000000000001001 164.0
HKD2_k127_7627580_6 - - - - 0.00000000000000000000000000005136 121.0
HKD2_k127_7649697_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 1.046e-282 872.0
HKD2_k127_7649697_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.116e-242 753.0
HKD2_k127_7649697_2 Belongs to the peptidase S11 family K01286,K07258 GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 610.0
HKD2_k127_7649697_3 YaaC-like Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 425.0
HKD2_k127_7649697_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 257.0
HKD2_k127_7649697_5 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000182 257.0
HKD2_k127_7649697_6 - - - - 0.00000000000006467 72.0
HKD2_k127_76720_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1323.0
HKD2_k127_76720_1 Carboxylesterase K03928 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 441.0
HKD2_k127_76720_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006324 246.0
HKD2_k127_76720_3 Preprotein translocase subunit SecG K03075 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - 0.00000000000000000000000003367 109.0
HKD2_k127_779485_0 Belongs to the ABC transporter superfamily K02031,K15583 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 524.0
HKD2_k127_779485_1 Belongs to the ABC transporter superfamily K02032 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 499.0
HKD2_k127_779485_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 481.0
HKD2_k127_779485_3 binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 408.0
HKD2_k127_779485_4 Phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 385.0
HKD2_k127_779485_5 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008972,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 321.0
HKD2_k127_779485_6 Acyl-CoA hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004826 275.0
HKD2_k127_779485_7 COG1247 Sortase and related acyltransferases K03823 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000000000000000000000448 258.0
HKD2_k127_779485_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000008983 78.0
HKD2_k127_7850841_0 YfkB-like domain - - - 8.447e-214 666.0
HKD2_k127_7850841_1 COG0387 Ca2 H antiporter K07300 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015368,GO:0015369,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051139,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 564.0
HKD2_k127_7850841_2 YfkD-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 433.0
HKD2_k127_7850841_3 - - - - 0.000003781 49.0
HKD2_k127_7854490_0 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid K06409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 418.0
HKD2_k127_7854490_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008608 254.0
HKD2_k127_785807_0 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 338.0
HKD2_k127_785807_1 Domain of unknown function (DUF4373) - - - 0.000000000000000000000000000000000000005408 156.0
HKD2_k127_785807_2 Cro/C1-type HTH DNA-binding domain K07727 - - 0.0000000000000000000000007696 112.0
HKD2_k127_785807_3 Replication initiation and membrane attachment - - - 0.000000000000000000007729 103.0
HKD2_k127_785807_4 Transcriptional regulator K07727 - - 0.000000000001299 70.0
HKD2_k127_7862871_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 574.0
HKD2_k127_7862871_1 xylanase chitin deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 396.0
HKD2_k127_7862871_2 n-acetylmuramoyl-L-alanine amidase K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 354.0
HKD2_k127_7862871_3 Involved in the activation of the KinB signaling pathway of sporulation K06349 GO:0008150,GO:0022603,GO:0042173,GO:0043937,GO:0043938,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001371 283.0
HKD2_k127_7862871_4 Spore gernimation protein K06294 - - 0.00000000000000000000000000000000000000000000000000000000000000000008475 235.0
HKD2_k127_7862871_5 Protein of unknown function (DUF2521) - - - 0.000000000000000000000000000000000000000000000000000000000000004179 219.0
HKD2_k127_7862871_6 - - - - 0.00000000000000000000000003013 109.0
HKD2_k127_7865367_0 Sodium:sulfate symporter transmembrane region - - - 1.325e-256 804.0
HKD2_k127_7865367_1 the major facilitator superfamily - - - 3.545e-222 698.0
HKD2_k127_7865367_10 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000006625 149.0
HKD2_k127_7865367_11 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000009138 127.0
HKD2_k127_7865367_12 COG0695 Glutaredoxin and related proteins - - - 0.000000000000000000000001458 104.0
HKD2_k127_7865367_13 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000001129 87.0
HKD2_k127_7865367_14 - - - - 0.00000000000003519 74.0
HKD2_k127_7865367_15 - - - - 0.000000000001713 70.0
HKD2_k127_7865367_16 - - - - 0.000001428 55.0
HKD2_k127_7865367_17 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000005384 49.0
HKD2_k127_7865367_2 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate K05823 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 1.205e-200 629.0
HKD2_k127_7865367_3 Diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 602.0
HKD2_k127_7865367_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 557.0
HKD2_k127_7865367_5 Chemotaxis protein CheV K03408,K03415 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 505.0
HKD2_k127_7865367_6 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate K00674,K05822 - 2.3.1.117,2.3.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 397.0
HKD2_k127_7865367_7 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 348.0
HKD2_k127_7865367_8 COG0517 FOG CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006121 247.0
HKD2_k127_7865367_9 YkyB-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001085 246.0
HKD2_k127_7866262_0 Fumarate reductase flavoprotein C-term - - - 1.827e-296 915.0
HKD2_k127_7866262_1 the major facilitator superfamily - - - 3.445e-264 819.0
HKD2_k127_7866262_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 4.725e-256 793.0
HKD2_k127_7866262_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 410.0
HKD2_k127_7866262_4 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 385.0
HKD2_k127_7866262_5 4Fe-4S ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000002921 213.0
HKD2_k127_7866262_6 PFAM Response regulator receiver domain K07775 - - 0.0000000000000000000000000000000000000000000000000001223 188.0
HKD2_k127_7866262_7 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000002993 166.0
HKD2_k127_7866262_8 - - - - 0.000000000001504 68.0
HKD2_k127_7882288_0 Histidine kinase K07652 - 2.7.13.3 0.0 1003.0
HKD2_k127_7882288_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 8.287e-266 820.0
HKD2_k127_7882288_10 YyzF-like protein - - - 0.00000000000000001377 83.0
HKD2_k127_7882288_11 - - - - 0.000000000000004975 76.0
HKD2_k127_7882288_13 - - - - 0.000000236 52.0
HKD2_k127_7882288_2 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 573.0
HKD2_k127_7882288_3 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 543.0
HKD2_k127_7882288_4 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 494.0
HKD2_k127_7882288_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 473.0
HKD2_k127_7882288_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07668 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 458.0
HKD2_k127_7882288_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002088 275.0
HKD2_k127_7882288_8 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000001276 186.0
HKD2_k127_7882288_9 Aminotransferase class-V - - - 0.000000000000000003656 83.0
HKD2_k127_788602_0 Metallo-beta-lactamase superfamily - - - 8.355e-195 613.0
HKD2_k127_788602_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 393.0
HKD2_k127_788602_10 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000003564 127.0
HKD2_k127_788602_11 membrane transporter protein K07090 - - 0.00000000000003598 73.0
HKD2_k127_788602_2 Cytochrome c K19713 - 1.8.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651 390.0
HKD2_k127_788602_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 370.0
HKD2_k127_788602_4 cytochrome c biogenesis protein K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 353.0
HKD2_k127_788602_5 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 286.0
HKD2_k127_788602_6 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003255 230.0
HKD2_k127_788602_7 Hypothetical methyltransferase - - - 0.00000000000000000000000000000000000000000000000000008483 193.0
HKD2_k127_788602_8 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000001118 171.0
HKD2_k127_788602_9 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000772 160.0
HKD2_k127_788696_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1984.0
HKD2_k127_788696_1 stage II sporulation protein E K06382 GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 3.1.3.16 0.0 1368.0
HKD2_k127_788696_10 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 329.0
HKD2_k127_788696_11 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 316.0
HKD2_k127_788696_12 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 313.0
HKD2_k127_788696_13 stage V sporulation protein K04769 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 307.0
HKD2_k127_788696_14 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 301.0
HKD2_k127_788696_15 spore cortex biosynthesis protein - GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000003416 246.0
HKD2_k127_788696_16 RNA binding protein (contains ribosomal protein S1 domain) K07571 - - 0.0000000000000000000000000000000000000000000000000000000000000000002967 231.0
HKD2_k127_788696_17 Sporulation protein YabP - GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000001505 200.0
HKD2_k127_788696_18 Septum formation initiator K13052 - - 0.000000000000000000000000000000000000001205 150.0
HKD2_k127_788696_19 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) - - - 0.0000000000000000000000000000000000005345 141.0
HKD2_k127_788696_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1090.0
HKD2_k127_788696_20 Peptide ABC transporter permease - - - 0.00000000000000000000000000000000222 130.0
HKD2_k127_788696_3 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 2.647e-241 752.0
HKD2_k127_788696_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 3.138e-211 661.0
HKD2_k127_788696_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075,K15780 - 2.4.2.8,6.3.4.19 3.476e-204 647.0
HKD2_k127_788696_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 567.0
HKD2_k127_788696_7 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid K03328 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 578.0
HKD2_k127_788696_8 serine threonine protein kinase K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 435.0
HKD2_k127_788696_9 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 404.0
HKD2_k127_7889053_0 Phosphoglucomutase K01835 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2 1.103e-290 900.0
HKD2_k127_7889053_1 Stage V sporulation protein R K06415 - - 7.473e-285 879.0
HKD2_k127_7889053_10 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 298.0
HKD2_k127_7889053_11 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 286.0
HKD2_k127_7889053_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000005379 237.0
HKD2_k127_7889053_13 ArsC family K16509 - - 0.0000000000000000000000000000000000000000000000000000000000000000000215 233.0
HKD2_k127_7889053_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004646 235.0
HKD2_k127_7889053_15 Required for disulfide bond formation in some proteins K03611 - - 0.000000000000000000000000000000000000000000000000000000000000000001311 229.0
HKD2_k127_7889053_16 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000001611 212.0
HKD2_k127_7889053_17 Family of unknown function (DUF5365) - - - 0.00000000000000000000000000000000000005788 146.0
HKD2_k127_7889053_18 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000000000835 141.0
HKD2_k127_7889053_19 YhdB-like protein - - - 0.000000000000000000000000000000004183 129.0
HKD2_k127_7889053_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 4.015e-215 676.0
HKD2_k127_7889053_20 YCII-related domain - - - 0.000000000000000000000000001045 114.0
HKD2_k127_7889053_21 Protein of unknown function (DUF3889) - - - 0.000000000000000000001377 98.0
HKD2_k127_7889053_22 SNARE associated Golgi protein K01077 - 3.1.3.1 0.000000000004048 67.0
HKD2_k127_7889053_23 SNARE associated Golgi protein K01077 - 3.1.3.1 0.00000001711 55.0
HKD2_k127_7889053_24 transcriptional regulator - - - 0.0000003481 59.0
HKD2_k127_7889053_3 Belongs to the AlaDH PNT family K00259 GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009653,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030435,GO:0032502,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 6.522e-195 616.0
HKD2_k127_7889053_4 phosphate transporter K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 560.0
HKD2_k127_7889053_5 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 434.0
HKD2_k127_7889053_6 Zn_pept K01308 - 3.4.19.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 419.0
HKD2_k127_7889053_7 COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 338.0
HKD2_k127_7889053_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 320.0
HKD2_k127_7889053_9 SNARE associated Golgi protein K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 314.0
HKD2_k127_7910326_0 DUF based on E. rectale Gene description (DUF3880) - - - 2.313e-252 797.0
HKD2_k127_7910326_1 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 557.0
HKD2_k127_7910326_2 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 560.0
HKD2_k127_7910326_3 Belongs to the peptidase S8 family K13274,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 560.0
HKD2_k127_7910326_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 491.0
HKD2_k127_7910326_5 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 464.0
HKD2_k127_7910326_6 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 392.0
HKD2_k127_7910326_7 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005783 276.0
HKD2_k127_7910326_8 VanZ like family - - - 0.000000000000000000000000000006414 125.0
HKD2_k127_7910326_9 - - - - 0.000000008204 57.0
HKD2_k127_7932709_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 0.0 1288.0
HKD2_k127_7932709_1 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 6.907e-238 743.0
HKD2_k127_7932709_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002346 263.0
HKD2_k127_7932709_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000003444 235.0
HKD2_k127_7932709_4 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000002843 153.0
HKD2_k127_8005369_0 DNA helicase K03654 GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 0.0 1047.0
HKD2_k127_8005369_1 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 502.0
HKD2_k127_8005369_2 Cold-inducible protein YdjO - - - 0.000000000000000000000000000004968 119.0
HKD2_k127_8005369_3 Cold-inducible protein YdjO - - - 0.00000000000000000000000000002446 118.0
HKD2_k127_8005369_4 Histidine kinase - - - 0.00000000000000000003846 96.0
HKD2_k127_805442_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075,K15780 - 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 606.0
HKD2_k127_805442_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 323.0
HKD2_k127_805442_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000001539 71.0
HKD2_k127_805442_3 stage II sporulation protein E K06382 GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 3.1.3.16 0.000000003101 57.0
HKD2_k127_8061409_0 - - - - 1.268e-282 882.0
HKD2_k127_8061409_1 Carboxylate--amine ligase - - - 2.67e-208 653.0
HKD2_k127_8061409_2 - - - - 0.0000000000000000000000000000000000000000000001533 171.0
HKD2_k127_8061409_3 - - - - 0.00000234 50.0
HKD2_k127_806238_0 COG1199 Rad3-related DNA helicases K03722 - 3.6.4.12 0.0 1078.0
HKD2_k127_806238_1 Cold shock K03704 - - 0.0000000000000000000000000000000000611 133.0
HKD2_k127_8064023_0 Transglycosylase K12555 - 2.4.1.129,3.4.16.4 1.458e-297 927.0
HKD2_k127_8064023_1 Belongs to the glutamate synthase family - - - 3.011e-292 902.0
HKD2_k127_8064023_2 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 312.0
HKD2_k127_8064023_3 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000005594 174.0
HKD2_k127_8064023_4 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000786 83.0
HKD2_k127_8076598_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1448.0
HKD2_k127_8076598_1 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564 3.4.21.102 1.211e-220 694.0
HKD2_k127_8076598_10 flagellar protein FliS K02422 - - 0.000000000000000000000000000000000000000000000000000000006014 200.0
HKD2_k127_8076598_11 transcriptional K19449 GO:0008150,GO:0009892,GO:0010468,GO:0010605,GO:0010629,GO:0019222,GO:0048519,GO:0050789,GO:0060255,GO:0065007 - 0.00000000000000000000000000000000000000000000001833 171.0
HKD2_k127_8076598_12 COG2010 Cytochrome c, mono- and diheme variants K12263,K13300 - - 0.000000000000000000000000000000000005464 141.0
HKD2_k127_8076598_13 bacterial-type flagellum organization K02423 - - 0.000000000000000000000000002632 115.0
HKD2_k127_8076598_14 - - - - 0.000000003029 62.0
HKD2_k127_8076598_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 598.0
HKD2_k127_8076598_3 peptidase K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 484.0
HKD2_k127_8076598_4 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 460.0
HKD2_k127_8076598_5 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 445.0
HKD2_k127_8076598_6 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0032506,GO:0034097,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 440.0
HKD2_k127_8076598_7 cell division ATP-binding protein FtsE K09812 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 348.0
HKD2_k127_8076598_8 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 305.0
HKD2_k127_8076598_9 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 286.0
HKD2_k127_8088974_0 Beta-eliminating lyase - - - 7.488e-271 837.0
HKD2_k127_8088974_1 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 302.0
HKD2_k127_8088974_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 293.0
HKD2_k127_8088974_3 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009548 244.0
HKD2_k127_8088974_4 Collagen triple helix repeat (20 copies) - - - 0.00000000000000000000000000000000000000000000003593 180.0
HKD2_k127_8088974_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.0004509 46.0
HKD2_k127_8094483_0 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 1.603e-239 743.0
HKD2_k127_8094483_1 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 557.0
HKD2_k127_8094483_2 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 417.0
HKD2_k127_8094483_3 Precorrin-6x reductase CbiJ/CobK K05895 - 1.3.1.106,1.3.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 408.0
HKD2_k127_8094483_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 377.0
HKD2_k127_8099175_0 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 585.0
HKD2_k127_8099175_1 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000007066 135.0
HKD2_k127_8110181_0 Domain of unknown function (DUF4179) - - - 1.451e-194 617.0
HKD2_k127_8110181_1 Bacterial regulatory proteins, lacI family K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 376.0
HKD2_k127_8110181_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000009006 88.0
HKD2_k127_8147455_0 Belongs to the LTA synthase family K19005 GO:0005575,GO:0005576 2.7.8.20 0.0 1078.0
HKD2_k127_8147455_1 DEAD_2 K07464 - 3.1.12.1 2.798e-199 637.0
HKD2_k127_8147455_2 - - - - 0.0000000000000000004558 89.0
HKD2_k127_8148202_0 Heparinase II/III N-terminus - - - 6.2e-322 1008.0
HKD2_k127_8148202_1 transferase activity, transferring glycosyl groups - - - 6.433e-209 658.0
HKD2_k127_8156396_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 3.857e-234 728.0
HKD2_k127_8156396_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 507.0
HKD2_k127_8156396_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 361.0
HKD2_k127_8156396_3 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 296.0
HKD2_k127_8156396_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000008283 254.0
HKD2_k127_8156396_5 protein conserved in bacteria - - - 0.00000000000000000000002922 100.0
HKD2_k127_8156396_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000007099 93.0
HKD2_k127_8156396_7 - K20109 - 3.4.24.89 0.000001963 51.0
HKD2_k127_8174013_0 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 439.0
HKD2_k127_8186949_0 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 560.0
HKD2_k127_8186949_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 533.0
HKD2_k127_8186949_10 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.00000000000000000000000000000001083 132.0
HKD2_k127_8186949_11 - - - - 0.00000000000000000000000001963 110.0
HKD2_k127_8186949_12 PFAM EAL domain - - - 0.0000000001154 64.0
HKD2_k127_8186949_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 481.0
HKD2_k127_8186949_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 457.0
HKD2_k127_8186949_4 ABC transporter, ATP-binding protein K20459 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 367.0
HKD2_k127_8186949_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 347.0
HKD2_k127_8186949_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 333.0
HKD2_k127_8186949_7 ABC-2 family transporter protein K20461 - - 0.000000000000000000000000000000000000000000000000000000005432 207.0
HKD2_k127_8186949_8 COG2002 Regulators of stationary sporulation gene expression K06284 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0042802,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - 0.00000000000000000000000000000000000000000002017 163.0
HKD2_k127_8186949_9 Permease - - - 0.00000000000000000000000000000000005106 143.0
HKD2_k127_8190881_0 Asparagine synthase K01953 - 6.3.5.4 1.996e-280 876.0
HKD2_k127_8190881_1 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 543.0
HKD2_k127_8190881_3 Hydrogenase isoenzymes formation protein HypD K04654 - - 0.000000000000169 69.0
HKD2_k127_8190881_4 Serine kinase of the HPr protein, regulates carbohydrate metabolism - - - 0.0000000405 56.0
HKD2_k127_8197033_0 GAF domain K02482 - 2.7.13.3 8.69e-254 800.0
HKD2_k127_8197033_1 Sigma-54 interaction domain K02481 - - 5.13e-199 629.0
HKD2_k127_8199889_0 nucleotide phosphatase activity, acting on free nucleotides - - - 4.447e-195 613.0
HKD2_k127_8199889_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 486.0
HKD2_k127_8199889_2 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 455.0
HKD2_k127_8199889_3 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000881 300.0
HKD2_k127_8199889_4 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001057 262.0
HKD2_k127_8199889_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000008741 141.0
HKD2_k127_8199889_6 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000004356 118.0
HKD2_k127_8199889_7 - - - - 0.00000002969 55.0
HKD2_k127_8220415_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 467.0
HKD2_k127_8220415_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009235 279.0
HKD2_k127_8220415_2 Transcriptional regulator - - - 0.0000000000000000000000000000000003163 132.0
HKD2_k127_8225897_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 591.0
HKD2_k127_8225897_1 Belongs to the phosphoglycerate kinase family K00927 GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 527.0
HKD2_k127_8225897_2 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain K05311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 484.0
HKD2_k127_8225897_3 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009933 422.0
HKD2_k127_8225897_4 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000001213 99.0
HKD2_k127_8235651_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 369.0
HKD2_k127_8235651_1 - - - - 0.00000000000000000000000000000000000002069 152.0
HKD2_k127_8235651_2 Molecular chaperone. Has ATPase activity K04079 - - 0.000000000000000000000008454 100.0
HKD2_k127_8262121_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 7.054e-230 724.0
HKD2_k127_8262121_1 Aminotransferase K00841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 601.0
HKD2_k127_8262121_2 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 437.0
HKD2_k127_8262121_3 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 412.0
HKD2_k127_8262121_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 408.0
HKD2_k127_8262121_5 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 344.0
HKD2_k127_8262121_6 phosphocarrier protein HPr K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000001838 139.0
HKD2_k127_8262121_7 protein conserved in bacteria - - - 0.00000000000000000000000000005466 117.0
HKD2_k127_8262121_8 - - - - 0.0000000000000000001235 89.0
HKD2_k127_8262624_0 DNA helicase K03654 GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 1.979e-203 644.0
HKD2_k127_8262624_1 Histidine kinase K07651 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 362.0
HKD2_k127_8262624_2 protein conserved in bacteria K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 362.0
HKD2_k127_8262624_3 Ferredoxin K05337 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.00000000000000000000000000000000000000000001072 164.0
HKD2_k127_8262624_4 Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - 0.0000000000000000000000004411 105.0
HKD2_k127_8262624_5 Lysin motif - - - 0.000008596 49.0
HKD2_k127_8289811_0 Zinc-binding dehydrogenase K00001,K18369 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 585.0
HKD2_k127_8289811_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 546.0
HKD2_k127_8289811_2 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001969 156.0
HKD2_k127_8289811_3 DNA integration - - - 0.0001273 45.0
HKD2_k127_8296131_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 338.0
HKD2_k127_8311720_0 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 9.19e-230 718.0
HKD2_k127_8311720_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 467.0
HKD2_k127_8311720_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 325.0
HKD2_k127_8311720_3 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 312.0
HKD2_k127_8311720_4 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000002234 189.0
HKD2_k127_8311720_5 Fibronectin type III-like domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.00005332 45.0
HKD2_k127_8314119_0 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 530.0
HKD2_k127_8314119_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 440.0
HKD2_k127_8314119_2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000335 180.0
HKD2_k127_8314119_3 - - - - 0.000000000000000000000000000000000003147 139.0
HKD2_k127_8337087_0 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 404.0
HKD2_k127_8337087_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 299.0
HKD2_k127_8337087_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000001516 108.0
HKD2_k127_8343308_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 588.0
HKD2_k127_8343308_1 Glycosyl transferases group 1 K19424 GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 502.0
HKD2_k127_8343308_2 EpsG family K19419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 475.0
HKD2_k127_8343308_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 318.0
HKD2_k127_8385803_0 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.0 1595.0
HKD2_k127_8385803_1 Multicopper oxidase K06324 - 1.16.3.3 3.614e-283 878.0
HKD2_k127_8385803_10 Transcriptional regulator TenI K10810 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.3.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000001812 258.0
HKD2_k127_8385803_11 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000005672 173.0
HKD2_k127_8385803_12 Glutaredoxin - - - 0.00000000000000000000000000000001135 128.0
HKD2_k127_8385803_13 Small, acid-soluble spore protein, gamma-type K06422 - - 0.00000000000000000000000000004642 119.0
HKD2_k127_8385803_14 Sigma-G-dependent sporulation-specific SASP protein - - - 0.00000000000000000000000002258 110.0
HKD2_k127_8385803_15 ComK protein - - - 0.00000000000000000000000004342 115.0
HKD2_k127_8385803_16 Thiamine biosynthesis K03154 - - 0.00000000000000000000001474 100.0
HKD2_k127_8385803_17 - - - - 0.00001196 50.0
HKD2_k127_8385803_2 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K03148,K21029 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779 2.7.7.73,2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009885 503.0
HKD2_k127_8385803_3 Glycine oxidase K00285,K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19,1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 489.0
HKD2_k127_8385803_4 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 454.0
HKD2_k127_8385803_5 deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 432.0
HKD2_k127_8385803_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 404.0
HKD2_k127_8385803_7 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 396.0
HKD2_k127_8385803_8 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 347.0
HKD2_k127_8385803_9 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 294.0
HKD2_k127_844171_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 350.0
HKD2_k127_844171_1 Serine hydrolase (FSH1) K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 324.0
HKD2_k127_844171_2 MerR family transcriptional regulator - - - 0.0002003 45.0
HKD2_k127_8479862_0 Belongs to the arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 489.0
HKD2_k127_8479862_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 327.0
HKD2_k127_8479862_10 - - - - 0.0000000000004212 68.0
HKD2_k127_8479862_12 - - - - 0.0002999 44.0
HKD2_k127_8479862_2 Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation - GO:0005575,GO:0016020 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 323.0
HKD2_k127_8479862_3 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 321.0
HKD2_k127_8479862_4 Transcriptional regulator K07979 - - 0.00000000000000000000000000000000000000000001825 164.0
HKD2_k127_8479862_5 - - - - 0.0000000000000000000000000000000000000000000571 170.0
HKD2_k127_8479862_6 - - - - 0.000000000000000000000001108 104.0
HKD2_k127_8479862_7 - - - - 0.0000000000000000002298 88.0
HKD2_k127_8479862_8 - - - - 0.0000000000000000002328 87.0
HKD2_k127_8479862_9 - - - - 0.0000000000003986 68.0
HKD2_k127_8487670_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 8.701e-253 784.0
HKD2_k127_8487670_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000001674 227.0
HKD2_k127_8543303_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 472.0
HKD2_k127_8543303_1 MerR family transcriptional regulator K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 387.0
HKD2_k127_8543303_2 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC K16511 GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001793 272.0
HKD2_k127_8543303_3 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000003685 196.0
HKD2_k127_8549559_0 chemotaxis protein K06595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 360.0
HKD2_k127_8549559_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.00000000000000000000000000001701 117.0
HKD2_k127_8549559_2 His Kinase A (phosphoacceptor) domain K07697 - 2.7.13.3 0.000000004959 64.0
HKD2_k127_8565828_0 FeS cluster assembly K07033,K09014 - - 9.927e-296 908.0
HKD2_k127_8565828_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 1.527e-244 757.0
HKD2_k127_8565828_10 COG0822 NifU homolog involved in Fe-S cluster formation K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000003541 231.0
HKD2_k127_8565828_11 Sporulation protein YunB (Spo_YunB) - - - 0.0000000000000000000000000000000000000000000000000000000000000001675 229.0
HKD2_k127_8565828_12 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) - - - 0.00000000000000000000000000000000000000000000000000000000001649 211.0
HKD2_k127_8565828_13 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system K02071 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - 0.0000000000000000000000000000000000000000000000000000004351 195.0
HKD2_k127_8565828_14 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000001501 183.0
HKD2_k127_8565828_15 Domain of unknown function (DUF1805) - - - 0.0000000000000000000000000000000000000000082 155.0
HKD2_k127_8565828_16 Protein of unknown function (DUF3055) - - - 0.00000000000000000000000000000000000000009924 151.0
HKD2_k127_8565828_17 - - - - 0.0000000000000000000000000000000147 128.0
HKD2_k127_8565828_18 - - - - 0.00000000000001008 75.0
HKD2_k127_8565828_2 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 9.981e-234 730.0
HKD2_k127_8565828_20 - - - - 0.00000001265 57.0
HKD2_k127_8565828_3 assembly protein SufD K07033,K09015 - - 2.137e-218 683.0
HKD2_k127_8565828_4 Peptidase, M23 K21472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 508.0
HKD2_k127_8565828_5 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 495.0
HKD2_k127_8565828_6 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 446.0
HKD2_k127_8565828_7 Belongs to the NlpA lipoprotein family K02072,K02073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 434.0
HKD2_k127_8565828_8 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 417.0
HKD2_k127_8565828_9 COG2011 ABC-type metal ion transport system, permease component K02069,K02072 GO:0000101,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015821,GO:0015849,GO:0016020,GO:0042940,GO:0044464,GO:0046942,GO:0048473,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072348 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 352.0
HKD2_k127_8590722_0 membrane protein involved in D-alanine export K03739 - - 8.733e-195 612.0
HKD2_k127_8590722_1 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) K03740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 605.0
HKD2_k127_8590722_2 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall K03367 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 0.000000000000000000000000000000000000004422 147.0
HKD2_k127_8590722_3 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall K14188 GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 0.000000000000000000000000000000001467 130.0
HKD2_k127_8592748_0 Glycoside Hydrolase Family K06306 - - 5.08e-240 745.0
HKD2_k127_8592748_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 314.0
HKD2_k127_8592748_2 spore protein K06419 - - 0.0000000000000000000000000000004575 122.0
HKD2_k127_8592748_3 potassium channel protein K10716 - - 0.0000000000000000008594 88.0
HKD2_k127_8592756_0 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 370.0
HKD2_k127_8592756_1 ArsR family transcriptional regulator K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000005037 203.0
HKD2_k127_8621117_0 HemY protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 598.0
HKD2_k127_8621117_1 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 329.0
HKD2_k127_8621117_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 300.0
HKD2_k127_8621117_3 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000007707 202.0
HKD2_k127_8621117_4 asexual reproduction K06425 - - 0.000000000000000000002015 96.0
HKD2_k127_8645336_0 Aldehyde dehydrogenase family K10217 - 1.2.1.32,1.2.1.85 5.651e-264 820.0
HKD2_k127_8645336_1 Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds K04073 - 1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 448.0
HKD2_k127_8645336_2 2-keto-4-pentenoate hydratase K02554 - 4.2.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 367.0
HKD2_k127_8645336_3 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 342.0
HKD2_k127_8645336_4 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds K01666 - 4.1.3.39 0.0000000000000000000000000001875 118.0
HKD2_k127_8645336_5 Protein of unknown function (DUF2524) - - - 0.00000000000000000000001981 104.0
HKD2_k127_8645336_6 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000002829 97.0
HKD2_k127_8645336_7 protein containing a divergent version of the methyl-accepting chemotaxis-like domain - - - 0.00009787 45.0
HKD2_k127_8662465_0 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0 1137.0
HKD2_k127_8662465_1 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 540.0
HKD2_k127_8662465_2 Belongs to the UPF0398 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008068 279.0
HKD2_k127_8662465_3 Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation - - - 0.0000000000000000000000000000000000000000000000000002481 185.0
HKD2_k127_8662465_4 Inner spore coat protein D K06327 - - 0.00000000000000000000000000007393 121.0
HKD2_k127_8664353_0 Transposase and inactivated derivatives K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 433.0
HKD2_k127_8664353_1 hydrolases of the HAD superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008397 392.0
HKD2_k127_8664353_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 285.0
HKD2_k127_8664353_3 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000009327 172.0
HKD2_k127_8664353_4 Belongs to the UPF0356 family - - - 0.00000000000000000000005135 99.0
HKD2_k127_8686912_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 481.0
HKD2_k127_8686912_1 PFAM Chemotaxis methyl-accepting receptor, signalling K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002038 290.0
HKD2_k127_8700386_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 5.483e-208 652.0
HKD2_k127_8700386_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 576.0
HKD2_k127_8700386_2 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress K05916,K15765 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0033554,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044270,GO:0044464,GO:0046209,GO:0046210,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051213,GO:0051409,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0071500,GO:0071949,GO:0072593,GO:0097159,GO:1901265,GO:1901363,GO:2001057 1.14.12.17,1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 478.0
HKD2_k127_8747985_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 2.57e-233 727.0
HKD2_k127_8747985_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 573.0
HKD2_k127_8747985_10 Peptidase M50B-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 297.0
HKD2_k127_8747985_11 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 288.0
HKD2_k127_8747985_12 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 286.0
HKD2_k127_8747985_13 COG2059 Chromate transport protein ChrA K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000448 258.0
HKD2_k127_8747985_14 COG2059 Chromate transport protein ChrA K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001798 252.0
HKD2_k127_8747985_15 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000000003023 219.0
HKD2_k127_8747985_16 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000006747 204.0
HKD2_k127_8747985_17 PFAM Response regulator receiver domain K07775 - - 0.00000000000000000000000000000000000000211 148.0
HKD2_k127_8747985_18 Protein of unknown function (DUF3892) - - - 0.000000000000000000000000000000000000003906 147.0
HKD2_k127_8747985_19 - - - - 0.0000000000001901 72.0
HKD2_k127_8747985_2 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 517.0
HKD2_k127_8747985_20 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000002535 55.0
HKD2_k127_8747985_21 - - - - 0.00001005 49.0
HKD2_k127_8747985_3 HemY protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 509.0
HKD2_k127_8747985_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 498.0
HKD2_k127_8747985_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 478.0
HKD2_k127_8747985_6 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 452.0
HKD2_k127_8747985_7 Catalyzes the reduction of alpha, beta-unsaturated aldehydes and ketones K00354 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 1.6.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 456.0
HKD2_k127_8747985_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 436.0
HKD2_k127_8747985_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 411.0
HKD2_k127_8750314_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 452.0
HKD2_k127_8750314_1 hydrolases of the HAD superfamily K21064 - 3.1.3.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 428.0
HKD2_k127_8750314_10 - - - - 0.0000000000005222 69.0
HKD2_k127_8750314_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 433.0
HKD2_k127_8750314_3 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 406.0
HKD2_k127_8750314_4 PFAM RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 404.0
HKD2_k127_8750314_5 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 346.0
HKD2_k127_8750314_6 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 333.0
HKD2_k127_8750314_7 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 279.0
HKD2_k127_8750314_8 metal-sulfur cluster biosynthetic enzyme - - - 0.000000000000000000000000000000000000000000000000007818 181.0
HKD2_k127_8750314_9 Protein of unknown function (DUF3813) - - - 0.000000000000001015 78.0
HKD2_k127_8757664_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 317.0
HKD2_k127_8757664_1 Histidine kinase K07697 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001534 274.0
HKD2_k127_8757664_2 sh3 domain protein K02450 - - 0.00000000000000000000000000000000000000000000000000000002917 204.0
HKD2_k127_8757664_3 - - - - 0.000000000000000000000000000000000000000000001289 166.0
HKD2_k127_8757664_4 - - - - 0.00000000000000000000000000001035 118.0
HKD2_k127_8757664_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000003042 64.0
HKD2_k127_8757664_6 PD-(D/E)XK nuclease superfamily K09124 - - 0.00003569 48.0
HKD2_k127_8805912_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 3.309e-228 715.0
HKD2_k127_8805912_1 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 515.0
HKD2_k127_8805912_10 - - - - 0.00003934 46.0
HKD2_k127_8805912_2 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 322.0
HKD2_k127_8805912_3 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 287.0
HKD2_k127_8805912_4 Thiamine-precursor transporter protein (ThiW) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007524 272.0
HKD2_k127_8805912_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051,K15598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002544 249.0
HKD2_k127_8805912_6 CHAD - - - 0.000000000000000000000000000000000000000000000000000000000000009177 227.0
HKD2_k127_8805912_7 TipAS antibiotic-recognition domain - - - 0.00000000000000000000000000000000000000000000000000000000000004189 217.0
HKD2_k127_8805912_8 - - - - 0.000000000000000000003564 94.0
HKD2_k127_8805912_9 nuclear chromosome segregation K13582 - - 0.000003599 53.0
HKD2_k127_8805946_0 AcrB/AcrD/AcrF family - - - 0.0 1073.0
HKD2_k127_8805946_1 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000207 198.0
HKD2_k127_8825_0 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 579.0
HKD2_k127_8825_1 cystathionine K01760,K17217 GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000006949 263.0
HKD2_k127_8825_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K17228 - 1.14.14.35 0.0000000000000000000000000000000000000000000000000000000000000006955 219.0
HKD2_k127_8831182_0 Parallel beta-helix repeats - - - 3.814e-273 854.0
HKD2_k127_8881232_0 Cupin domain K00450 - 1.13.11.4 4.723e-226 702.0
HKD2_k127_8881232_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 1.197e-208 658.0
HKD2_k127_8881232_2 FAD binding domain K22270 - 1.14.13.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 533.0
HKD2_k127_8881232_3 DinB superfamily - - - 0.000000000000000000000000000000000003407 138.0
HKD2_k127_8915394_0 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K01847 - 5.4.99.2 0.0 1300.0
HKD2_k127_8915394_1 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 2.995e-297 916.0
HKD2_k127_8915394_10 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K09699 - 2.3.1.12,2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 522.0
HKD2_k127_8915394_11 Flagellar Assembly Protein A K09749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 499.0
HKD2_k127_8915394_12 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process K07699 GO:0000003,GO:0000156,GO:0000160,GO:0000910,GO:0003674,GO:0006355,GO:0007049,GO:0007154,GO:0007165,GO:0008150,GO:0008356,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0019954,GO:0022402,GO:0022603,GO:0022607,GO:0023052,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032506,GO:0035556,GO:0042173,GO:0042710,GO:0043934,GO:0043937,GO:0043938,GO:0044010,GO:0044085,GO:0044764,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051171,GO:0051252,GO:0051301,GO:0051704,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090529,GO:0090604,GO:0090606,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 467.0
HKD2_k127_8915394_13 Putative aromatic acid exporter C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 444.0
HKD2_k127_8915394_14 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002072 256.0
HKD2_k127_8915394_15 Belongs to the UPF0403 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009663 247.0
HKD2_k127_8915394_16 COG0346 Lactoylglutathione lyase and related lyases K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000003201 218.0
HKD2_k127_8915394_17 Protein of unknown function (DUF2627) - - - 0.0000000000000000000000000003151 115.0
HKD2_k127_8915394_2 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K01847 - 5.4.99.2 6.585e-271 846.0
HKD2_k127_8915394_20 - - - - 0.0001477 46.0
HKD2_k127_8915394_3 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 3.025e-270 836.0
HKD2_k127_8915394_4 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 5.249e-233 728.0
HKD2_k127_8915394_5 COG2195 Di- and tripeptidases K01258,K01263 - 3.4.11.14,3.4.11.4 1.178e-203 638.0
HKD2_k127_8915394_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0050896 2.7.7.7 2.383e-201 634.0
HKD2_k127_8915394_7 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167,K21417 - 1.2.4.4 6.993e-196 612.0
HKD2_k127_8915394_8 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 595.0
HKD2_k127_8915394_9 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00166 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 583.0
HKD2_k127_8918850_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.143e-300 926.0
HKD2_k127_8918850_1 - - - - 0.00000000000000000004538 91.0
HKD2_k127_8918850_2 - - - - 0.000002178 49.0
HKD2_k127_8922238_0 AMP-binding enzyme C-terminal domain - - - 1.463e-282 875.0
HKD2_k127_8922238_1 Acyl-CoA dehydrogenase, C-terminal domain K06446 - - 2.642e-197 620.0
HKD2_k127_8922238_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 580.0
HKD2_k127_8922238_3 Acyl-CoA dehydrogenase, N-terminal domain K04117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 546.0
HKD2_k127_8922238_4 Enoyl-CoA hydratase/isomerase K01661 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 482.0
HKD2_k127_8922238_5 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 461.0
HKD2_k127_8922238_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K07535,K10620 - 1.3.1.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 399.0
HKD2_k127_8922238_7 dehydratase - - - 0.0000000000000000000000000000000000000001153 154.0
HKD2_k127_8922238_8 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000034 82.0
HKD2_k127_8968961_0 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 403.0
HKD2_k127_8968961_1 - - - - 0.000000000000000000000000000000000000007982 151.0
HKD2_k127_8968961_2 Protein of unknown function (DUF1657) - - - 0.00000000000000000000000000521 111.0
HKD2_k127_8968961_3 Protein of unknown function (DUF1657) - - - 0.0000000000000001664 80.0
HKD2_k127_8968961_4 Threonine aldolase K01620 - 4.1.2.48 0.00000000000004535 75.0
HKD2_k127_898543_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 457.0
HKD2_k127_898543_1 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001496 281.0
HKD2_k127_898543_2 - - - - 0.000000000000000000000000000000000000000000000000000002123 197.0
HKD2_k127_898543_3 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000001525 184.0
HKD2_k127_898543_4 Peptidase M56 - - - 0.00000001596 65.0
HKD2_k127_898543_5 Peptidase M56 K02172 - - 0.000286 52.0
HKD2_k127_9003780_0 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 327.0
HKD2_k127_9003780_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000000000913 195.0
HKD2_k127_9003780_3 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000005391 190.0
HKD2_k127_9003780_4 Asp23 family, cell envelope-related function - - - 0.000000000000000000000000000001436 124.0
HKD2_k127_9053242_0 Y_Y_Y domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 341.0
HKD2_k127_9053242_1 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003292 265.0
HKD2_k127_9053242_2 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000006069 197.0
HKD2_k127_9053242_3 PFAM glycoside hydrolase family 39 - - - 0.00000000000000003107 96.0
HKD2_k127_9086676_0 penicillin-binding protein K21465 - - 0.0 1101.0
HKD2_k127_9086676_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 477.0
HKD2_k127_9086676_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 462.0
HKD2_k127_9086676_3 Phosphate K02040 GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 460.0
HKD2_k127_9086676_4 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 456.0
HKD2_k127_9087371_0 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K22187 - - 1.158e-230 721.0
HKD2_k127_9087371_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 524.0
HKD2_k127_9087371_2 Acetolactate synthase - - - 0.00000000000000000000000000000000000000000087 164.0
HKD2_k127_9087371_3 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000006946 84.0
HKD2_k127_9087371_4 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000006646 73.0
HKD2_k127_9087371_5 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains - - - 0.0000000005198 60.0
HKD2_k127_909330_0 Oxidoreductase K19285 - 1.5.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 392.0
HKD2_k127_909330_1 Putative amidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007946 394.0
HKD2_k127_909330_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 297.0
HKD2_k127_909330_3 Ser protein kinase K07180 - - 0.0000000000000000000000000000000000000000000000000000000000005048 211.0
HKD2_k127_9096316_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1127.0
HKD2_k127_9096316_1 rRNA methylase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 486.0
HKD2_k127_9096316_2 - - - - 0.00002242 48.0
HKD2_k127_9105770_0 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 524.0
HKD2_k127_9105770_1 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 GO:0003674,GO:0003824,GO:0016787 4.2.99.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 346.0
HKD2_k127_9105770_2 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.00000001472 55.0
HKD2_k127_9111744_0 COG2199 FOG GGDEF domain - - - 9.932e-242 762.0
HKD2_k127_9111744_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 404.0
HKD2_k127_9111744_2 methionine gamma-lyase K01761 - 4.4.1.11 0.000000000000000000000000000000000000001102 149.0
HKD2_k127_9111744_3 helix_turn_helix, mercury resistance - - - 0.000000000000000000002379 98.0
HKD2_k127_9111744_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000001333 49.0
HKD2_k127_9114443_0 membrane protein (homolog of Drosophila rhomboid) K19225 - 3.4.21.105 7.336e-201 638.0
HKD2_k127_9114443_1 Glucokinase K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 498.0
HKD2_k127_9114443_11 - - - - 0.00000000000000007427 81.0
HKD2_k127_9114443_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 317.0
HKD2_k127_9114443_3 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 306.0
HKD2_k127_9114443_4 PFAM Glycoside hydrolase 15-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 283.0
HKD2_k127_9114443_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001215 286.0
HKD2_k127_9114443_6 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000001281 244.0
HKD2_k127_9114443_7 protein conserved in bacteria - - - 0.0000000000000000000000003544 106.0
HKD2_k127_9114443_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000002276 100.0
HKD2_k127_9114443_9 Protein of unknown function (DUF2759) - - - 0.0000000000000000001261 89.0
HKD2_k127_9124211_0 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 1.301e-292 909.0
HKD2_k127_9124211_1 ABC transporter K06147 - - 8.822e-239 750.0
HKD2_k127_9124211_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.133e-209 661.0
HKD2_k127_9124211_3 tRNA 2-selenouridine synthase K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 441.0
HKD2_k127_9159221_0 ATP-dependent helicase nuclease subunit A K16898 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 0.0 1810.0
HKD2_k127_9159221_1 ATP-dependent helicase deoxyribonuclease subunit B K16899 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 0.0 1144.0
HKD2_k127_9159221_10 - - - - 0.00000000000000000000000000000000000000000000000003285 181.0
HKD2_k127_9159221_11 Spore germination protein gerPA/gerPF K06299,K06304 - - 0.000000000000000000000000188 106.0
HKD2_k127_9159221_13 Spore germination protein GerPE K06303 - - 0.000000000004254 67.0
HKD2_k127_9159221_2 Peptidase M48 - GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564 - 1.029e-208 656.0
HKD2_k127_9159221_3 ATP-dependent helicase deoxyribonuclease subunit B K16899 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 8.132e-197 619.0
HKD2_k127_9159221_4 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 347.0
HKD2_k127_9159221_5 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 321.0
HKD2_k127_9159221_6 phosphohydrolase K06950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 306.0
HKD2_k127_9159221_7 Competence transcription factor K02250 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 284.0
HKD2_k127_9159221_8 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001392 281.0
HKD2_k127_9159221_9 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001136 277.0
HKD2_k127_916254_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 8.225e-200 630.0
HKD2_k127_916254_1 DNA methylase K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 530.0
HKD2_k127_916254_2 EcsC protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 405.0
HKD2_k127_916254_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 293.0
HKD2_k127_916254_4 - - - - 0.000000000000000000000000000000000000003874 148.0
HKD2_k127_916254_5 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000001169 98.0
HKD2_k127_916254_6 - - - - 0.00003188 47.0
HKD2_k127_9195563_0 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 1.07e-315 972.0
HKD2_k127_9195563_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.899e-293 904.0
HKD2_k127_9195563_10 COG2165 Type II secretory pathway, pseudopilin PulG K02246 - - 0.0000000000000004897 83.0
HKD2_k127_9195563_11 YqzE-like protein - - - 0.0000000000002371 71.0
HKD2_k127_9195563_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 2.715e-234 730.0
HKD2_k127_9195563_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 582.0
HKD2_k127_9195563_4 COG0607 Rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000000000000000000002768 190.0
HKD2_k127_9195563_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000000000002407 180.0
HKD2_k127_9195563_6 Bacterial protein YqhG of unknown function - - - 0.0000000000000000000000000000000000000000000000003259 185.0
HKD2_k127_9195563_7 COG4940 Competence protein ComGF K02248 - - 0.00000000000000000000000000000000000001146 149.0
HKD2_k127_9195563_8 Required for transformation and DNA binding K02245 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000002921 136.0
HKD2_k127_9283426_0 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 393.0
HKD2_k127_9283426_1 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 364.0
HKD2_k127_9283426_2 MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 331.0
HKD2_k127_9283898_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 1.306e-275 854.0
HKD2_k127_9283898_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 439.0
HKD2_k127_9283898_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 394.0
HKD2_k127_9283898_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 325.0
HKD2_k127_9283898_4 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000007639 212.0
HKD2_k127_9307109_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 523.0
HKD2_k127_9307109_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K05816,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 388.0
HKD2_k127_9307109_2 Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a. Its N-terminus first activates urm1 and mocs2a as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and mocs2a. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor K11996,K22132 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0061605,GO:0070566,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 350.0
HKD2_k127_9324507_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 487.0
HKD2_k127_9324507_1 NAD(P)H-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 342.0
HKD2_k127_9324507_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000005285 63.0
HKD2_k127_9324507_12 alcohol dehydrogenase K18382 - - 0.00002409 48.0
HKD2_k127_9324507_2 HPP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 335.0
HKD2_k127_9324507_3 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 314.0
HKD2_k127_9324507_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004895 263.0
HKD2_k127_9324507_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000003113 232.0
HKD2_k127_9324507_6 Alkylphosphonate utilization protein K06193 - - 0.00000000000000000000000000000000000000000000000000000000000006291 217.0
HKD2_k127_9324507_7 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000168 209.0
HKD2_k127_9324507_8 transcriptional K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000005326 149.0
HKD2_k127_9324507_9 Family of unknown function (DUF5392) - - - 0.0000000000000000000000000000000001062 138.0
HKD2_k127_9324941_0 Acetylornithine deacetylase K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 574.0
HKD2_k127_9324941_1 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01034 - 2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 349.0
HKD2_k127_9324941_2 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01035 - 2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 314.0
HKD2_k127_9324941_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000005075 193.0
HKD2_k127_9331208_0 Transcriptional regulator - - - 9.082e-269 837.0
HKD2_k127_9331208_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 3.782e-202 634.0
HKD2_k127_9331208_2 acyl-CoA transferases carnitine dehydratase - - - 3.925e-196 617.0
HKD2_k127_9331208_3 Acyl-CoA dehydrogenase, N-terminal domain K00249,K11731 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 577.0
HKD2_k127_9331208_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 533.0
HKD2_k127_9331208_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 439.0
HKD2_k127_9331208_6 Cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 389.0
HKD2_k127_9331208_7 Protein of unknown function with PCYCGC motif - - - 0.00000000000000000000000000000000000000000000000000000000000000005571 226.0
HKD2_k127_9331208_8 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000000000000000000000000000000000000004873 146.0
HKD2_k127_9331208_9 DoxX K15977 - - 0.0000000000000000000000000000001203 124.0
HKD2_k127_9333771_0 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 0.0 1853.0
HKD2_k127_9333771_1 WXG100 protein secretion system (Wss), protein YukC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 443.0
HKD2_k127_9333771_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002146 233.0
HKD2_k127_9333771_3 WXG100 protein secretion system (Wss), protein YukD - - - 0.0000000000000000000000000000000001522 133.0
HKD2_k127_9333771_4 Belongs to the WXG100 family - - - 0.0000000000000000000000000000002815 125.0
HKD2_k127_9336632_0 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00161 - 1.2.4.1 1.379e-207 648.0
HKD2_k127_9336632_1 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162 - 1.2.4.1 1.559e-194 608.0
HKD2_k127_9336632_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 537.0
HKD2_k127_9339360_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.886e-313 965.0
HKD2_k127_9339360_1 zinc metalloprotease K11749 - - 1.638e-229 715.0
HKD2_k127_9339360_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 603.0
HKD2_k127_9339360_3 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K03763 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 448.0
HKD2_k127_9339360_4 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001251 274.0
HKD2_k127_9354324_0 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase K07777 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 559.0
HKD2_k127_9354324_1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K02479,K07692 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 398.0
HKD2_k127_9354324_2 Domain of unknown function (DUF1949) K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 327.0
HKD2_k127_9354324_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001045 256.0
HKD2_k127_9366581_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.0 1048.0
HKD2_k127_9366581_1 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue K04766 GO:0001101,GO:0003674,GO:0003824,GO:0006066,GO:0006355,GO:0006950,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009056,GO:0009267,GO:0009605,GO:0009847,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010034,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016407,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019152,GO:0019219,GO:0019222,GO:0019751,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032502,GO:0033554,GO:0034077,GO:0034078,GO:0034311,GO:0034313,GO:0042149,GO:0042180,GO:0042182,GO:0042221,GO:0042594,GO:0042844,GO:0042846,GO:0043894,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045013,GO:0045014,GO:0045149,GO:0045150,GO:0045892,GO:0045934,GO:0045990,GO:0046015,GO:0046164,GO:0046174,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0061984,GO:0061985,GO:0061986,GO:0065007,GO:0070887,GO:0071229,GO:0071236,GO:0071310,GO:0071311,GO:0071496,GO:0071704,GO:0080090,GO:1901575,GO:1901615,GO:1901616,GO:1901700,GO:1901701,GO:1902652,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 353.0
HKD2_k127_9366581_2 Acetoin utilization protein AcuB K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 314.0
HKD2_k127_9366581_3 histone deacetylase K04768 - - 0.0000000000000000000000000005233 115.0
HKD2_k127_9367550_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 3.979e-304 936.0
HKD2_k127_9367550_1 the major facilitator superfamily - - - 2.387e-245 766.0
HKD2_k127_9367550_10 COG1309 Transcriptional regulator - - - 0.0000000000000000000000000000000000000002571 153.0
HKD2_k127_9367550_11 COG1309 Transcriptional regulator - - - 0.000000000001516 68.0
HKD2_k127_9367550_2 Benzoate membrane transport protein - - - 7.653e-196 617.0
HKD2_k127_9367550_3 Uncharacterised MFS-type transporter YbfB K05548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 602.0
HKD2_k127_9367550_4 Uncharacterized protein conserved in bacteria (DUF2252) K13730 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 541.0
HKD2_k127_9367550_5 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001925 277.0
HKD2_k127_9367550_6 SdpI/YhfL protein family - GO:0008150,GO:0009636,GO:0042221,GO:0050896 - 0.000000000000000000000000000000000000000000000000000000000000259 218.0
HKD2_k127_9367550_7 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000114 205.0
HKD2_k127_9367550_8 Antibiotic biosynthesis monooxygenase K07145 - 1.14.99.48 0.00000000000000000000000000000000000000000000000000008921 188.0
HKD2_k127_9367550_9 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000000000000000002655 188.0
HKD2_k127_9381113_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 2.522e-296 922.0
HKD2_k127_9381113_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000116 281.0
HKD2_k127_9382575_0 Penicillin-binding Protein K21468 - - 1.818e-278 865.0
HKD2_k127_9382575_1 Could be a S-adenosyl-L-methionine-dependent methyltransferase K17462 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 318.0
HKD2_k127_9382575_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001657 242.0
HKD2_k127_9382575_3 Protein of unknown function (DUF1510) - - - 0.00000000000000000000000000000000000000000000000000000000000000001283 229.0
HKD2_k127_9382575_4 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000001007 220.0
HKD2_k127_9382575_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000007923 205.0
HKD2_k127_9382575_6 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.0000000000000000000000000000005055 122.0
HKD2_k127_9382575_7 - - - - 0.000000000000000000000000000001373 124.0
HKD2_k127_9382575_8 Protein of unknown function (DUF2536) - - - 0.00000000000000000000002922 100.0
HKD2_k127_9382575_9 - - - - 0.0000000000000000000007096 100.0
HKD2_k127_9382712_0 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006922 270.0
HKD2_k127_9382712_1 General stress protein - - - 0.000000000000000000000000000000000000000000000000000000003889 201.0
HKD2_k127_9382712_2 Small acid-soluble spore protein H family K06425 - - 0.00000000000000000004402 90.0
HKD2_k127_9401577_0 Belongs to the peptidase S16 family K07177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 504.0
HKD2_k127_9401577_1 Sporulation integral membrane protein YlbJ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 481.0
HKD2_k127_9401577_11 - - - - 0.00007671 46.0
HKD2_k127_9401577_2 esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 423.0
HKD2_k127_9401577_3 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 310.0
HKD2_k127_9401577_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003106 263.0
HKD2_k127_9401577_5 Methylthioribose kinase - - - 0.0000000000000000000000000000000000000000000000000000000000006038 212.0
HKD2_k127_9401577_6 - - - - 0.0000000000000000000000000000000000000000000001155 187.0
HKD2_k127_9401577_7 Domain of Unknown Function (DUF1540) - - - 0.00000000000000000000001842 101.0
HKD2_k127_9401577_8 Belongs to the UPF0348 family - - - 0.0000000000000009428 78.0
HKD2_k127_9401613_0 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 5.388e-296 916.0
HKD2_k127_9401613_1 Stage IV sporulation protein B K06399 - 3.4.21.116 2.532e-222 694.0
HKD2_k127_9401613_2 Regulates arginine biosynthesis genes K03402 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 280.0
HKD2_k127_9401613_4 - - - - 0.0002962 43.0
HKD2_k127_9421558_0 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 595.0
HKD2_k127_9421558_1 membrane-bound metal-dependent K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 542.0
HKD2_k127_9421558_10 YpzG-like protein - - - 0.00001681 48.0
HKD2_k127_9421558_2 nucleoside-diphosphate sugar epimerase K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 417.0
HKD2_k127_9421558_3 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 374.0
HKD2_k127_9421558_4 Protein of unknown function (DUF1811) - - - 0.000000000000000000000000000000000000000000000000008036 181.0
HKD2_k127_9421558_5 WVELL protein - - - 0.0000000000000000000000000000000001054 134.0
HKD2_k127_9421558_6 reproduction K06428 - - 0.00000000000000003512 84.0
HKD2_k127_9421558_7 YfhD-like protein - - - 0.0000001226 54.0
HKD2_k127_9456939_0 penicillin-binding protein K21465 - - 7.078e-315 976.0
HKD2_k127_9456939_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 3.35e-273 843.0
HKD2_k127_9456939_10 YheC/D like ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 409.0
HKD2_k127_9456939_11 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 390.0
HKD2_k127_9456939_12 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 304.0
HKD2_k127_9456939_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000005673 208.0
HKD2_k127_9456939_14 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000001074 181.0
HKD2_k127_9456939_15 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000006574 149.0
HKD2_k127_9456939_16 - - - - 0.0000000000000000000000000000000001522 133.0
HKD2_k127_9456939_17 - - - - 0.0000000000000000000000000000000001682 136.0
HKD2_k127_9456939_18 Family of unknown function (DUF5342) - - - 0.0000000000000000000000005489 105.0
HKD2_k127_9456939_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 3.67e-271 839.0
HKD2_k127_9456939_20 Belongs to the UPF0754 family - - - 0.0000000000284 66.0
HKD2_k127_9456939_21 - - - - 0.00000004705 55.0
HKD2_k127_9456939_3 Major facilitator superfamily - - - 1.619e-238 746.0
HKD2_k127_9456939_4 YheC/D like ATP-grasp - GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - 8.787e-225 703.0
HKD2_k127_9456939_5 cystathionine K01760 GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.8 1.729e-205 644.0
HKD2_k127_9456939_6 cystathionine K01739 GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48 3.578e-201 631.0
HKD2_k127_9456939_7 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 453.0
HKD2_k127_9456939_8 YheC/D like ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 423.0
HKD2_k127_9456939_9 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 400.0
HKD2_k127_946075_0 HD domain - - - 2.266e-217 683.0
HKD2_k127_946075_1 High-affinity nickel-transport protein K07241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 389.0
HKD2_k127_946075_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 386.0
HKD2_k127_946075_4 COG0642 Signal transduction histidine kinase - - - 0.0000000000000369 72.0
HKD2_k127_9468756_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 599.0
HKD2_k127_9468756_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 512.0
HKD2_k127_9468756_2 ABC transporter (permease) K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 515.0
HKD2_k127_9468756_3 stage VI sporulation protein D K06417 GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 339.0
HKD2_k127_9468756_4 - - - - 0.0000000005986 61.0
HKD2_k127_9515906_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 575.0
HKD2_k127_9515906_1 Y_Y_Y domain - - - 0.000000000000000000000000000000000000000000005017 169.0
HKD2_k127_9515906_2 tRNA 2-selenouridine synthase K06917 - - 0.000000618 51.0
HKD2_k127_9518928_0 hydrolase family 65, central catalytic K10231,K18784 - 2.4.1.230,2.4.1.282 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000944 532.0
HKD2_k127_953315_0 COG0513 Superfamily II DNA and RNA helicases - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 590.0
HKD2_k127_953315_1 phosphohydrolase (DHH superfamily) K07097 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 569.0
HKD2_k127_953315_2 Histidine kinase K02491,K13533 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 493.0
HKD2_k127_953315_3 Riboflavin synthase K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 327.0
HKD2_k127_953315_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 310.0
HKD2_k127_953315_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 282.0
HKD2_k127_953315_6 Rubrerythrin - - - 0.00000000000000000000000000000000000001304 148.0
HKD2_k127_953315_7 3D domain - - - 0.00000000000000000009646 90.0
HKD2_k127_9609112_0 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000001999 241.0
HKD2_k127_9609112_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000009389 218.0
HKD2_k127_9609112_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000001038 187.0
HKD2_k127_9609112_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000001401 93.0
HKD2_k127_96207_0 COG1253 Hemolysins and related proteins containing CBS domains - - - 4.667e-239 745.0
HKD2_k127_96207_1 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000006243 218.0
HKD2_k127_9686354_0 ABC transporter (Permease K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009918 274.0
HKD2_k127_9686354_1 Molybdenum cofactor biosynthesis protein K03637,K03639,K20967 - 4.1.99.22,4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000005705 240.0
HKD2_k127_9686354_2 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000002525 169.0
HKD2_k127_9686354_3 - - - - 0.0000000000000000000000173 102.0
HKD2_k127_9686354_4 - - - - 0.000006658 50.0
HKD2_k127_9692212_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.0 1104.0
HKD2_k127_9692212_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 572.0
HKD2_k127_9692212_10 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4 K02277 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000003228 145.0
HKD2_k127_9692212_11 YlbE-like protein - - - 0.00000000000000000000000000000008362 125.0
HKD2_k127_9692212_12 - - - - 0.000000000000000000000000002131 116.0
HKD2_k127_9692212_13 UPF0298 protein - - - 0.0000000000000000976 79.0
HKD2_k127_9692212_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 474.0
HKD2_k127_9692212_3 cytochrome c oxidase K02862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 454.0
HKD2_k127_9692212_4 protein with SCP PR1 domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 443.0
HKD2_k127_9692212_5 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008906 377.0
HKD2_k127_9692212_6 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003099 258.0
HKD2_k127_9692212_7 YugN-like family - - - 0.0000000000000000000000000000000000000000000000000000000007733 202.0
HKD2_k127_9692212_8 Belongs to the UPF0342 family - - - 0.00000000000000000000000000000000000000000000000000000000174 203.0
HKD2_k127_9692212_9 Putative coat protein - - - 0.00000000000000000000000000000000000000000297 159.0
HKD2_k127_96935_0 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 469.0
HKD2_k127_96935_1 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 430.0
HKD2_k127_96935_2 NADH dehydrogenase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 364.0
HKD2_k127_96935_3 general stress protein K06884 - - 0.0000000000000002364 81.0
HKD2_k127_96935_4 Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000003482 78.0
HKD2_k127_9706969_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 5.658e-253 783.0
HKD2_k127_9706969_1 Rod shape-determining protein MreB K03569 - - 2.46e-197 617.0
HKD2_k127_9706969_10 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 GO:0000910,GO:0003674,GO:0004857,GO:0007049,GO:0007105,GO:0008150,GO:0009987,GO:0022402,GO:0030234,GO:0031333,GO:0032271,GO:0032272,GO:0032506,GO:0043086,GO:0043254,GO:0044087,GO:0044092,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 363.0
HKD2_k127_9706969_11 Belongs to the UPF0735 family K06209 - 5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005377 266.0
HKD2_k127_9706969_12 septum formation protein Maf K06287 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003305 263.0
HKD2_k127_9706969_13 small molecule binding protein (contains 3H domain) K07105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006919 246.0
HKD2_k127_9706969_14 Sporulation initiation phospho-transferase B, C-terminal K06375 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000001488 245.0
HKD2_k127_9706969_15 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001236 192.0
HKD2_k127_9706969_16 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000000000000000000000000001599 186.0
HKD2_k127_9706969_17 COG0739 Membrane proteins related to metalloendopeptidases K06401 - - 0.0000000000000000000000000000000000000000000000001087 186.0
HKD2_k127_9706969_18 ribosomal protein K07584 - - 0.0000000000000000000000000000000000000000000000001411 178.0
HKD2_k127_9706969_19 shape-determining protein K03571 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000001257 179.0
HKD2_k127_9706969_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 577.0
HKD2_k127_9706969_20 - K06380 - - 0.0000000000000000000000000000000000000000001911 169.0
HKD2_k127_9706969_21 PFAM Fimbrial assembly family protein K02663 - - 0.00000000000000000000000000003258 124.0
HKD2_k127_9706969_22 - K02664 - - 0.0000000000000000000000000005006 126.0
HKD2_k127_9706969_23 - - - - 0.0000001186 53.0
HKD2_k127_9706969_24 COG4972 Tfp pilus assembly protein, ATPase PilM K02662,K02663 - - 0.00004156 46.0
HKD2_k127_9706969_25 - K06380 - - 0.0002688 44.0
HKD2_k127_9706969_26 Lysin motif - - - 0.0003753 52.0
HKD2_k127_9706969_3 Belongs to the ParA family K03609 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 496.0
HKD2_k127_9706969_4 Cysteine desulfurase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 482.0
HKD2_k127_9706969_5 COG1994 Zn-dependent proteases K06402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 451.0
HKD2_k127_9706969_6 Prephenate dehydratase K04518 GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 446.0
HKD2_k127_9706969_7 ribonuclease, Rne Rng family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007821 435.0
HKD2_k127_9706969_8 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 407.0
HKD2_k127_9706969_9 Involved in formation and maintenance of cell shape K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 402.0
HKD2_k127_9712940_0 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 593.0
HKD2_k127_9712940_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 417.0
HKD2_k127_9712940_10 Phospholipase_D-nuclease N-terminal - - - 0.0000000001827 63.0
HKD2_k127_9712940_11 - - - - 0.00001506 47.0
HKD2_k127_9712940_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 398.0
HKD2_k127_9712940_3 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 336.0
HKD2_k127_9712940_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000001029 220.0
HKD2_k127_9712940_5 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000000000000372 179.0
HKD2_k127_9712940_6 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.0000000000000000000000000000000000000004504 158.0
HKD2_k127_9712940_7 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.00000000000000000000000000000000000005938 144.0
HKD2_k127_9712940_8 - - - - 0.000000000000000002489 86.0
HKD2_k127_9712940_9 Family of unknown function (DUF5345) - - - 0.0000000001549 66.0
HKD2_k127_97545_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1765.0
HKD2_k127_97545_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 612.0
HKD2_k127_97545_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 589.0
HKD2_k127_97545_3 acetylornithine aminotransferase K00821 GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 555.0
HKD2_k127_97545_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 526.0
HKD2_k127_97545_5 Carbamoyl-phosphate synthetase glutamine chain K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 430.0
HKD2_k127_97545_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 397.0
HKD2_k127_97545_7 YjzC-like protein - - - 0.000000000000000000000006286 102.0
HKD2_k127_9768460_0 Endoribonuclease that initiates mRNA decay K18682 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 7.801e-303 932.0
HKD2_k127_9768460_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 595.0
HKD2_k127_9768460_2 protein conserved in bacteria K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 493.0
HKD2_k127_9768460_3 COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 452.0
HKD2_k127_9768460_4 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 299.0
HKD2_k127_9768460_5 Stage V sporulation protein S K06416 - - 0.000000000000000000000000000000000000000001395 157.0
HKD2_k127_9768460_6 - - - - 0.000001888 50.0
HKD2_k127_9805528_0 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 0.0 1199.0
HKD2_k127_9805528_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 6.314e-303 934.0
HKD2_k127_9805528_2 Ferrous iron transport protein B C terminus K04759 - - 4.414e-248 770.0
HKD2_k127_9805528_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 401.0
HKD2_k127_9805528_4 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 372.0
HKD2_k127_9805528_5 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 293.0
HKD2_k127_9805528_6 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004948 240.0
HKD2_k127_9805528_7 - - - - 0.0000000000000000004855 87.0
HKD2_k127_9805528_8 - - - - 0.0000000000001102 75.0
HKD2_k127_9805528_9 Short C-terminal domain K08982 - - 0.0000000000002435 72.0
HKD2_k127_9823864_0 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 6.022e-296 911.0
HKD2_k127_9823864_1 Major Facilitator K08369 - - 6.662e-195 614.0
HKD2_k127_9853608_0 membrane-associated HD superfamily hydrolase K07037 - - 1.17e-247 783.0
HKD2_k127_9853608_1 COG1030 Membrane-bound serine protease (ClpP class) K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 609.0
HKD2_k127_9853608_10 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009972,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 3.5.4.5 0.000000000000000000000000000000000000000000000000000000000001371 211.0
HKD2_k127_9853608_11 sporulation protein YqfC - - - 0.00000000000000000000000000000000000000003395 153.0
HKD2_k127_9853608_12 ribosomal protein S12 methylthiotransferase K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000000000000000000000008005 143.0
HKD2_k127_9853608_13 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.00000000000000000000000000000001678 130.0
HKD2_k127_9853608_14 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000007816 101.0
HKD2_k127_9853608_2 Stage IV sporulation K06438 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 586.0
HKD2_k127_9853608_3 Phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 550.0
HKD2_k127_9853608_4 UPF0365 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 541.0
HKD2_k127_9853608_5 COG1283 Na phosphate symporter K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 394.0
HKD2_k127_9853608_6 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 359.0
HKD2_k127_9853608_7 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 325.0
HKD2_k127_9853608_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007542 251.0
HKD2_k127_9853608_9 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000000000000002047 229.0
HKD2_k127_9872820_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 406.0
HKD2_k127_9872820_1 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen K11159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 385.0
HKD2_k127_9872820_2 - - - - 0.0000000000000000000000000000000000000000000000000000000002552 211.0
HKD2_k127_9872820_3 - - - - 0.0000355 46.0
HKD2_k127_9872820_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00003588 48.0
HKD2_k127_9885111_0 cell septum assembly - - - 1.224e-267 858.0
HKD2_k127_9885111_1 Inorganic pyrophosphatase K15986 GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 502.0
HKD2_k127_9885111_2 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 452.0
HKD2_k127_9885111_3 IDEAL - - - 0.0000000000000003914 79.0
HKD2_k127_989834_0 Belongs to the aldehyde dehydrogenase family. RocA subfamily K00294 - 1.2.1.88 2.014e-288 890.0
HKD2_k127_989834_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 8.071e-203 639.0
HKD2_k127_989834_10 Quinone oxidoreductase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002542 273.0
HKD2_k127_989834_11 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004492 261.0
HKD2_k127_989834_12 COG0671 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000006122 255.0
HKD2_k127_989834_13 YmaF family - - - 0.000000000000000000000000000000000000000000000000000000000000004726 217.0
HKD2_k127_989834_14 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000000000000000000000771 204.0
HKD2_k127_989834_15 Small acid-soluble spore protein H family K06425 - - 0.000000000000000000000003225 102.0
HKD2_k127_989834_16 - - - - 0.0000000000000000000003154 98.0
HKD2_k127_989834_17 Protein of unknown function (DUF2680) - - - 0.00000000000000449 80.0
HKD2_k127_989834_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 582.0
HKD2_k127_989834_3 Glycosyl Transferase K19002 - 2.4.1.337 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 566.0
HKD2_k127_989834_4 Domain of unknown function (DUF2935) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 497.0
HKD2_k127_989834_5 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 493.0
HKD2_k127_989834_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 488.0
HKD2_k127_989834_7 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 398.0
HKD2_k127_989834_8 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 411.0
HKD2_k127_989834_9 ABC transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 290.0
HKD2_k127_9951602_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0 1106.0
HKD2_k127_9951602_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 7.428e-265 820.0
HKD2_k127_9951602_10 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 318.0
HKD2_k127_9951602_11 single-stranded nucleic acid binding R3H K06346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 312.0
HKD2_k127_9951602_12 Sporulation protein YyaC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 296.0
HKD2_k127_9951602_13 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 292.0
HKD2_k127_9951602_14 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000000000000000000000000000000000000000000424 191.0
HKD2_k127_9951602_15 S4 domain K14761 - - 0.000000000000000000000000000002796 121.0
HKD2_k127_9951602_16 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000001446 83.0
HKD2_k127_9951602_17 - - - - 0.0000007625 51.0
HKD2_k127_9951602_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 5.351e-260 805.0
HKD2_k127_9951602_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 1.847e-212 666.0
HKD2_k127_9951602_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 550.0
HKD2_k127_9951602_5 COG1192 ATPases involved in chromosome partitioning K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 461.0
HKD2_k127_9951602_6 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 462.0
HKD2_k127_9951602_7 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 408.0
HKD2_k127_9951602_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins K03217 GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 410.0
HKD2_k127_9951602_9 Belongs to the ParB family K03497 GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 365.0
HKD2_k127_9961282_0 malate quinone oxidoreductase K00116 - 1.1.5.4 5.077e-292 900.0
HKD2_k127_9961282_1 COG0515 Serine threonine protein kinase - - - 1.325e-211 661.0
HKD2_k127_9961282_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 580.0
HKD2_k127_9961282_3 NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 559.0
HKD2_k127_9961282_4 Belongs to the BI1 family K06890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 289.0
HKD2_k127_9961282_5 COG0477 Permeases of the major facilitator superfamily K08221 - - 0.000000000000000000000000000000000000000000000000000000000004349 209.0
HKD2_k127_9961282_6 - - - - 0.000000000000000000000000000000000000000000001114 169.0
HKD2_k127_9984815_0 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 388.0
HKD2_k127_9984815_1 drug exporters of the RND superfamily K06994,K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 346.0
HKD2_k127_9984815_2 Belongs to the glycosyl hydrolase 31 family - - - 0.00000000000000000000000000000000000000009036 173.0