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Overview

ID MAG01814
Name HKD2_bin.70
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Actinomycetes
Order Mycobacteriales
Family Frankiaceae
Genus
Species
Assembly information
Completeness (%) 81.14
Contamination (%) 0.73
GC content (%) 75.0
N50 (bp) 9,963
Genome size (bp) 3,323,194

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3450

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10011664_0 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000721 108.0
HKD2_k127_10011664_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000002072 74.0
HKD2_k127_10011664_2 Domain of unknown function (DUF3377) K07763,K07995,K07996,K07997,K08002,K08003 GO:0000003,GO:0000902,GO:0000904,GO:0001501,GO:0001503,GO:0001525,GO:0001541,GO:0001558,GO:0001568,GO:0001666,GO:0001704,GO:0001706,GO:0001763,GO:0001838,GO:0001935,GO:0001944,GO:0001952,GO:0001953,GO:0001958,GO:0002009,GO:0002165,GO:0002218,GO:0002253,GO:0002376,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002694,GO:0002696,GO:0003006,GO:0003007,GO:0003143,GO:0003144,GO:0003313,GO:0003314,GO:0003315,GO:0003318,GO:0003319,GO:0003674,GO:0003824,GO:0004175,GO:0004177,GO:0004222,GO:0004252,GO:0005102,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005768,GO:0005794,GO:0005796,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006928,GO:0006929,GO:0006935,GO:0006950,GO:0006979,GO:0007154,GO:0007162,GO:0007267,GO:0007275,GO:0007276,GO:0007292,GO:0007369,GO:0007399,GO:0007409,GO:0007411,GO:0007413,GO:0007417,GO:0007419,GO:0007424,GO:0007426,GO:0007444,GO:0007492,GO:0007503,GO:0007505,GO:0007507,GO:0007548,GO:0007552,GO:0007560,GO:0007561,GO:0008037,GO:0008038,GO:0008045,GO:0008047,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008236,GO:0008237,GO:0008238,GO:0008270,GO:0008283,GO:0008285,GO:0008347,GO:0008406,GO:0008584,GO:0008585,GO:0008593,GO:0009056,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009887,GO:0009888,GO:0009893,GO:0009897,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0010646,GO:0010648,GO:0010810,GO:0010812,GO:0010830,GO:0010831,GO:0010952,GO:0010954,GO:0012505,GO:0014070,GO:0016020,GO:0016021,GO:0016043,GO:0016331,GO:0016477,GO:0016485,GO:0016504,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0019953,GO:0022008,GO:0022411,GO:0022414,GO:0022617,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030155,GO:0030162,GO:0030178,GO:0030182,GO:0030198,GO:0030234,GO:0030307,GO:0030323,GO:0030324,GO:0030334,GO:0030335,GO:0030425,GO:0030574,GO:0030728,GO:0031175,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031347,GO:0031349,GO:0031410,GO:0031638,GO:0031974,GO:0031982,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032963,GO:0032989,GO:0032990,GO:0034330,GO:0034769,GO:0035050,GO:0035148,GO:0035202,GO:0035239,GO:0035295,GO:0035987,GO:0035988,GO:0036075,GO:0036293,GO:0036477,GO:0040008,GO:0040011,GO:0040012,GO:0040017,GO:0040036,GO:0040037,GO:0042060,GO:0042063,GO:0042127,GO:0042221,GO:0042330,GO:0042470,GO:0042995,GO:0043005,GO:0043009,GO:0043062,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043615,GO:0043627,GO:0044087,GO:0044093,GO:0044238,GO:0044352,GO:0044354,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044877,GO:0045088,GO:0045089,GO:0045111,GO:0045137,GO:0045165,GO:0045168,GO:0045216,GO:0045577,GO:0045579,GO:0045595,GO:0045597,GO:0045619,GO:0045621,GO:0045746,GO:0045862,GO:0045927,GO:0046331,GO:0046528,GO:0046529,GO:0046545,GO:0046546,GO:0046660,GO:0046661,GO:0046872,GO:0046914,GO:0048468,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048563,GO:0048568,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048608,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048701,GO:0048704,GO:0048705,GO:0048706,GO:0048707,GO:0048729,GO:0048731,GO:0048754,GO:0048770,GO:0048771,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050673,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050839,GO:0050864,GO:0050865,GO:0050867,GO:0050871,GO:0050896,GO:0051094,GO:0051128,GO:0051129,GO:0051147,GO:0051149,GO:0051153,GO:0051155,GO:0051171,GO:0051173,GO:0051179,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051249,GO:0051251,GO:0051270,GO:0051272,GO:0051336,GO:0051345,GO:0051604,GO:0051674,GO:0051704,GO:0051893,GO:0051895,GO:0052547,GO:0060255,GO:0060322,GO:0060348,GO:0060349,GO:0060350,GO:0060429,GO:0060541,GO:0060562,GO:0060612,GO:0060828,GO:0060973,GO:0061134,GO:0061138,GO:0061448,GO:0061458,GO:0061564,GO:0065007,GO:0065009,GO:0070006,GO:0070011,GO:0070013,GO:0070482,GO:0070613,GO:0071704,GO:0071711,GO:0071840,GO:0071944,GO:0072091,GO:0072175,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090090,GO:0090109,GO:0090287,GO:0090288,GO:0097094,GO:0097156,GO:0097447,GO:0097458,GO:0097485,GO:0097708,GO:0098552,GO:0098772,GO:0106030,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:0140096,GO:1901201,GO:1901202,GO:1901564,GO:1901888,GO:1901889,GO:1902105,GO:1902107,GO:1903053,GO:1903054,GO:1903317,GO:1903319,GO:1903391,GO:1903392,GO:1903706,GO:1903708,GO:1904888,GO:1905521,GO:1905523,GO:1990834,GO:2000026,GO:2000145,GO:2000147,GO:2000647 3.4.24.80 0.00001459 53.0
HKD2_k127_10082851_0 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 8.025e-294 912.0
HKD2_k127_10082851_1 Mandelate racemase muconate lactonizing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 503.0
HKD2_k127_10082851_10 - - - - 0.0000000000000004429 87.0
HKD2_k127_10082851_12 antisigma factor binding K02066 - - 0.000000571 61.0
HKD2_k127_10082851_13 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000005492 49.0
HKD2_k127_10082851_2 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 321.0
HKD2_k127_10082851_3 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001172 292.0
HKD2_k127_10082851_4 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000000000000000000001944 193.0
HKD2_k127_10082851_5 - - - - 0.000000000000000000000000000000000000000000001809 173.0
HKD2_k127_10082851_7 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000002286 119.0
HKD2_k127_10082851_8 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000008383 109.0
HKD2_k127_10082851_9 - - - - 0.0000000000000000002056 93.0
HKD2_k127_10112004_0 PFAM Alcohol dehydrogenase GroES-like domain K00001,K00344 - 1.1.1.1,1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 490.0
HKD2_k127_10112004_1 PFAM Alcohol dehydrogenase GroES domain protein K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000001532 256.0
HKD2_k127_10131791_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 394.0
HKD2_k127_10131791_1 Branched-chain amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 333.0
HKD2_k127_10131791_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 319.0
HKD2_k127_10131791_3 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 304.0
HKD2_k127_10131791_4 MarR family - - - 0.000000000000000000000000000001694 126.0
HKD2_k127_10131791_5 PFAM Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000000000003465 121.0
HKD2_k127_10131791_6 STAS domain - - - 0.000000000001756 72.0
HKD2_k127_10148693_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 524.0
HKD2_k127_10148693_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 331.0
HKD2_k127_10148693_2 PIN domain K07064 GO:0005575,GO:0005576 - 0.0000000001321 67.0
HKD2_k127_10148693_3 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000003749 65.0
HKD2_k127_10148693_4 - - - - 0.000000003032 63.0
HKD2_k127_10209158_0 phosphoglycerate mutase K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 554.0
HKD2_k127_10209158_1 Arsenical pump membrane protein K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 446.0
HKD2_k127_10209158_2 C4-type zinc ribbon domain K07164 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 301.0
HKD2_k127_10209158_3 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000007244 196.0
HKD2_k127_1104838_0 - - - - 0.000000000000000000000000000000000000000002114 170.0
HKD2_k127_1104838_1 TIGRFAM small GTP-binding protein K06945 - - 0.0000000000000000000000000000000000005187 148.0
HKD2_k127_1104838_2 distant relative of homeotic protein bithoraxoid K07131 - - 0.0000000000000000000000000001842 121.0
HKD2_k127_1130526_0 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0 1151.0
HKD2_k127_1130526_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 600.0
HKD2_k127_1130526_2 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000006977 239.0
HKD2_k127_1133566_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000021 288.0
HKD2_k127_1133566_1 nitric oxide dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000257 210.0
HKD2_k127_1133566_2 COG0569 K transport systems, NAD-binding component K03499 - - 0.0000000000000000000000000000000000000000082 155.0
HKD2_k127_1133566_3 ApbE family K03734 - 2.7.1.180 0.0000000000000000000000000000000000000003163 163.0
HKD2_k127_1133566_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000003623 151.0
HKD2_k127_1133566_5 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region - - - 0.000000000000000001678 97.0
HKD2_k127_1133566_6 4Fe-4S single cluster domain - - - 0.00000000000000009011 93.0
HKD2_k127_1133566_7 Winged helix-turn helix - - - 0.0002356 43.0
HKD2_k127_1143328_0 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 399.0
HKD2_k127_1143328_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000006903 246.0
HKD2_k127_1143328_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000333 215.0
HKD2_k127_1143328_3 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000009914 203.0
HKD2_k127_1143328_4 manually curated - - - 0.00000000000000005157 80.0
HKD2_k127_1143328_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000005324 64.0
HKD2_k127_1143328_6 Resolvase, N terminal domain - - - 0.000001612 51.0
HKD2_k127_1206329_0 Hydrolase - - - 0.0 1129.0
HKD2_k127_1206329_1 PFAM Glycosyl transferase, group 1 - - - 4.122e-232 732.0
HKD2_k127_1206329_2 ABC transporter K01990,K09691,K09693 - 3.6.3.40 8.095e-194 626.0
HKD2_k127_1206329_3 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 630.0
HKD2_k127_1206329_4 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 473.0
HKD2_k127_1206329_5 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 417.0
HKD2_k127_1206329_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 400.0
HKD2_k127_1206329_7 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000007978 269.0
HKD2_k127_1272405_0 PFAM UvrD REP helicase K03657 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 7.603e-302 941.0
HKD2_k127_1272405_1 manually curated - - - 0.00000000000000005157 80.0
HKD2_k127_1274092_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 337.0
HKD2_k127_1274092_1 Cytochrome b K03891 - - 0.00000000000000000000000000000000000000000004892 169.0
HKD2_k127_1274092_2 Cytochrome b K03891 - - 0.0000000000000000000000000000000000006967 143.0
HKD2_k127_1320552_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 1.298e-211 685.0
HKD2_k127_1320552_1 PFAM PfkB domain protein K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 517.0
HKD2_k127_1320552_2 PFAM aminotransferase class V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 533.0
HKD2_k127_1320552_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 404.0
HKD2_k127_1320552_4 Belongs to the glycerate kinase type-1 family K00865 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 360.0
HKD2_k127_1320552_5 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000006288 198.0
HKD2_k127_1320552_6 Belongs to the sulfur carrier protein TusA family K04487 - 2.8.1.7 0.000000000000000000003949 107.0
HKD2_k127_133833_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1020.0
HKD2_k127_133833_1 amino acid K03294 - - 1.265e-196 625.0
HKD2_k127_133833_2 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 517.0
HKD2_k127_133833_3 Lysylphosphatidylglycerol synthase TM region K07027,K20468 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 332.0
HKD2_k127_133833_4 PFAM ROK family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 338.0
HKD2_k127_133833_5 Belongs to the binding-protein-dependent transport system permease family K10544 - - 0.00000000000000000000000000000000000000000000001063 173.0
HKD2_k127_1341217_0 ABC transporter - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 3.483e-302 932.0
HKD2_k127_1341217_1 SMART alpha amylase, catalytic sub domain K01187 - 3.2.1.20 5.797e-234 762.0
HKD2_k127_1341217_10 PFAM globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000005513 217.0
HKD2_k127_1341217_11 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000527 233.0
HKD2_k127_1341217_12 Fe-S oxidoreductase K11473 - - 0.00000000000000000000000000000000000000000000000000000001785 222.0
HKD2_k127_1341217_13 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000002593 209.0
HKD2_k127_1341217_14 CRISPR-associated protein Cse2 (CRISPR_cse2) K19046 - - 0.000000000000000000000000000001482 136.0
HKD2_k127_1341217_15 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000000000001791 108.0
HKD2_k127_1341217_16 Histidine kinase-like ATPase domain - - - 0.00000000000000000007047 94.0
HKD2_k127_1341217_17 - - - - 0.0000001709 61.0
HKD2_k127_1341217_2 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 7.482e-216 679.0
HKD2_k127_1341217_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 544.0
HKD2_k127_1341217_4 CRISPR-associated helicase Cas3 K07012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 475.0
HKD2_k127_1341217_5 CRISPR-associated protein Cse1 (CRISPR_cse1) K19123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 451.0
HKD2_k127_1341217_6 Metallo-beta-lactamase superfamily K05555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 382.0
HKD2_k127_1341217_7 Alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 329.0
HKD2_k127_1341217_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 325.0
HKD2_k127_1341217_9 Metal dependent phosphohydrolases with conserved 'HD' motif. K07012,K19123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007206 257.0
HKD2_k127_1351897_0 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 463.0
HKD2_k127_1351897_1 Contains patatin domain. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40 of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 301.0
HKD2_k127_1351897_2 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005451 304.0
HKD2_k127_1351897_3 restriction endonuclease domain protein K01155 - 3.1.21.4 0.00000000000000000000000000000000000000000000000000000000005376 207.0
HKD2_k127_1351897_4 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000006976 194.0
HKD2_k127_1351897_5 BsuBI/PstI restriction endonuclease C-terminus K07317 - 2.1.1.72 0.0000000000000000000000000000000000000000001468 167.0
HKD2_k127_1351897_6 - - - - 0.00000000000000000000005409 101.0
HKD2_k127_1351897_7 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000001528 90.0
HKD2_k127_1351897_8 - - - - 0.0002898 49.0
HKD2_k127_1353339_0 PFAM ABC-1 domain protein - - - 4.933e-229 738.0
HKD2_k127_1353339_1 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 596.0
HKD2_k127_1353339_2 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 475.0
HKD2_k127_1353339_3 UBA THIF-type NAD FAD binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 345.0
HKD2_k127_1353339_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 321.0
HKD2_k127_1353339_5 metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000001495 226.0
HKD2_k127_1353339_6 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000003811 144.0
HKD2_k127_1353339_7 - - - - 0.0000000000000000003036 94.0
HKD2_k127_1353339_8 Dodecin K09165 - - 0.00000000000000001499 97.0
HKD2_k127_1353339_9 Protein of unknown function (DUF3018) - - - 0.0000000000000002073 81.0
HKD2_k127_1366577_0 F420-dependent oxidoreductase K12234 GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 593.0
HKD2_k127_1366577_1 tigrfam lppg K11212 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 417.0
HKD2_k127_1366577_2 3-methyladenine DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 327.0
HKD2_k127_136694_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0 1017.0
HKD2_k127_136694_1 adenylate kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001415 243.0
HKD2_k127_136694_2 acetylesterase activity - - - 0.000000000000000000000006064 117.0
HKD2_k127_136694_3 Domain of unknown function (DUF3367) - - - 0.0000000000000000000000403 104.0
HKD2_k127_136694_4 acetylesterase activity - - - 0.000000002202 66.0
HKD2_k127_136694_5 alpha beta - - - 0.0000005376 62.0
HKD2_k127_1370493_0 pyruvate phosphate dikinase, PEP K01006 - 2.7.9.1 0.0 1454.0
HKD2_k127_1370493_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 4.172e-291 910.0
HKD2_k127_1370493_2 SMART Metal-dependent phosphohydrolase, HD region K01129 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 556.0
HKD2_k127_1370493_3 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002434 247.0
HKD2_k127_1370493_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000105 232.0
HKD2_k127_1370493_5 PFAM Bacterial membrane flanked domain - - - 0.00000000000000000000000000000000000000000000000000000000001162 211.0
HKD2_k127_1370493_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000003524 81.0
HKD2_k127_1372844_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0 1155.0
HKD2_k127_1372844_1 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 371.0
HKD2_k127_1372844_2 Replication initiator protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 377.0
HKD2_k127_1372844_3 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 301.0
HKD2_k127_1372844_4 Helix-turn-helix domain - - - 0.00000000001318 67.0
HKD2_k127_1407801_0 Belongs to the D-alanine--D-alanine ligase family K01921 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 503.0
HKD2_k127_1407801_1 PFAM alpha amylase, catalytic K05341 - 2.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 444.0
HKD2_k127_1407801_10 sequence-specific DNA binding - - - 0.00000428 59.0
HKD2_k127_1407801_2 Glycerol-3-phosphate dehydrogenase K00057 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 442.0
HKD2_k127_1407801_3 PFAM Phosphomethylpyrimidine kinase type-1 K00941 GO:0008150,GO:0040007 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 406.0
HKD2_k127_1407801_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0008150,GO:0040007 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 400.0
HKD2_k127_1407801_5 Amidohydrolase family K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 304.0
HKD2_k127_1407801_6 Protein of unknown function (DUF3515) - - - 0.00000000000000000000000000000000007712 143.0
HKD2_k127_1407801_7 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000002596 133.0
HKD2_k127_1407801_9 Acyltransferase K00655 - 2.3.1.51 0.00000000000000001635 85.0
HKD2_k127_1424586_0 permease K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 554.0
HKD2_k127_1424586_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 514.0
HKD2_k127_1424586_10 PFAM regulatory protein, MarR - - - 0.0001109 46.0
HKD2_k127_1424586_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 376.0
HKD2_k127_1424586_3 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 344.0
HKD2_k127_1424586_4 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000000000000000005578 167.0
HKD2_k127_1424586_5 Methyltransferase domain - - - 0.00000000000000000000000000652 128.0
HKD2_k127_1424586_6 Protein of unknown function (DUF2530) - - - 0.000000000000000000000002205 106.0
HKD2_k127_1424586_8 Evidence 2b Function of strongly homologous gene K07497 - - 0.000000001079 63.0
HKD2_k127_1424586_9 Transposase DDE domain group 1 - - - 0.000003874 53.0
HKD2_k127_1436359_0 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 401.0
HKD2_k127_1436359_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 334.0
HKD2_k127_1436359_2 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000009191 240.0
HKD2_k127_1436359_3 PIN domain - - - 0.00000000000000000000000000000000000000000000000003379 186.0
HKD2_k127_1436359_4 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000000000000000006061 133.0
HKD2_k127_1436359_5 YCII-related domain K09780 - - 0.0000000000000000000000471 108.0
HKD2_k127_1436359_6 - - - - 0.000000000007128 73.0
HKD2_k127_1436359_7 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.0000001417 61.0
HKD2_k127_143856_0 Type II/IV secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 358.0
HKD2_k127_143856_1 type II secretion system - - - 0.00000000000000000000000000000000000000628 167.0
HKD2_k127_143856_2 bacterial-type flagellum organization - - - 0.00000000000000000000000000000004388 145.0
HKD2_k127_143856_3 SAF - - - 0.00000000000000000001109 105.0
HKD2_k127_143856_4 - - - - 0.000005252 59.0
HKD2_k127_143856_5 TadE-like protein - - - 0.00002821 55.0
HKD2_k127_1451767_0 Manganese containing catalase K07217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000132 269.0
HKD2_k127_1451767_1 Aldose 1-epimerase K01785 - 5.1.3.3 0.00000000000000000000000000000000000001053 149.0
HKD2_k127_1463859_0 heat shock protein 70 K04043 - - 1.264e-263 826.0
HKD2_k127_1463859_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 443.0
HKD2_k127_1463859_2 tellurium resistance protein K05792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 342.0
HKD2_k127_1463859_3 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 316.0
HKD2_k127_1463859_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ - - - 0.000000000000000000000000000000000000000000000000000000000004809 224.0
HKD2_k127_1463859_5 Stress protein K05791 - - 0.00000000000000000000000000001009 127.0
HKD2_k127_1472152_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.0 1193.0
HKD2_k127_1472152_1 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002522 286.0
HKD2_k127_1472152_2 PFAM Abortive infection protein K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003836 250.0
HKD2_k127_1472152_3 PFAM Penicillinase repressor - - - 0.000000000000000000000000000000000000000000005372 166.0
HKD2_k127_1472152_4 sh3 domain protein - - - 0.0000000000000000000119 99.0
HKD2_k127_1472152_5 cyclic-guanylate-specific phosphodiesterase activity - - - 0.0000000000000000003635 101.0
HKD2_k127_1472152_6 TIGRFAM Diguanylate cyclase - - - 0.000006375 54.0
HKD2_k127_1514492_0 Belongs to the GPI family K01810 - 5.3.1.9 1.639e-258 805.0
HKD2_k127_1514492_1 UDP binding domain K02472,K13015 - 1.1.1.136,1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 551.0
HKD2_k127_1514492_10 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002134 246.0
HKD2_k127_1514492_11 Protein of unknown function (DUF4012) - - - 0.0000000000000000000000000000000000000000000000000000000000006478 220.0
HKD2_k127_1514492_12 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000001652 209.0
HKD2_k127_1514492_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0008150,GO:0040007 5.4.99.18 0.000000000000000000000000000000000000000000000000000000001438 221.0
HKD2_k127_1514492_14 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000001338 206.0
HKD2_k127_1514492_15 low molecular weight K01104 - 3.1.3.48 0.00000000000000000000000000000000002739 144.0
HKD2_k127_1514492_16 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000565 143.0
HKD2_k127_1514492_17 Putative restriction endonuclease - - - 0.0000000000000000000000000000002786 138.0
HKD2_k127_1514492_18 Putative restriction endonuclease - - - 0.00000000000000000000000000002234 131.0
HKD2_k127_1514492_19 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000004543 114.0
HKD2_k127_1514492_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 451.0
HKD2_k127_1514492_21 - - - - 0.00000000000002383 85.0
HKD2_k127_1514492_23 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000007776 64.0
HKD2_k127_1514492_24 domain, Protein - - - 0.000000671 59.0
HKD2_k127_1514492_25 sugar transferase - - - 0.00003744 48.0
HKD2_k127_1514492_26 PIN domain - - - 0.00005684 46.0
HKD2_k127_1514492_3 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 364.0
HKD2_k127_1514492_4 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 332.0
HKD2_k127_1514492_5 Protein of unknown function (DUF4012) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 313.0
HKD2_k127_1514492_6 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 292.0
HKD2_k127_1514492_7 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007035 289.0
HKD2_k127_1514492_8 Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004859 266.0
HKD2_k127_1514492_9 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001714 263.0
HKD2_k127_1524060_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 7.888e-209 653.0
HKD2_k127_1524060_1 Pfam Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 594.0
HKD2_k127_1524060_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 536.0
HKD2_k127_1524060_3 tyrosine recombinase K03733,K04763 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 421.0
HKD2_k127_1524060_4 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001332 269.0
HKD2_k127_1524060_5 PFAM Cobyrinic acid a,c-diamide synthase K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000003263 162.0
HKD2_k127_1542170_0 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 527.0
HKD2_k127_1542170_1 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 434.0
HKD2_k127_1542170_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000008467 65.0
HKD2_k127_1542425_0 Belongs to the malate synthase family K01638 - 2.3.3.9 2.582e-242 758.0
HKD2_k127_1542425_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.306e-213 685.0
HKD2_k127_1542425_2 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 600.0
HKD2_k127_1542425_3 Fe-S oxidoreductase K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 419.0
HKD2_k127_1542425_4 PFAM FAD linked oxidase domain protein K00102,K00104,K11472 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 317.0
HKD2_k127_1542425_5 Fe-S oxidoreductase K11473 - - 0.00000000000000000000000000000000000000000000000000000000005781 223.0
HKD2_k127_1542425_6 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000009331 166.0
HKD2_k127_1556538_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 2.019e-215 679.0
HKD2_k127_1556538_1 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 517.0
HKD2_k127_1556538_2 PFAM helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 294.0
HKD2_k127_1556538_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 293.0
HKD2_k127_1556538_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000001547 175.0
HKD2_k127_1556538_5 Belongs to the CarA family - - - 0.00000000000000000000000000000000000001274 166.0
HKD2_k127_1556538_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000003467 107.0
HKD2_k127_1570329_0 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 423.0
HKD2_k127_1570329_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000003292 179.0
HKD2_k127_1570329_2 Universal stress protein family - - - 0.00000000000000000000000003249 114.0
HKD2_k127_1570329_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000001835 92.0
HKD2_k127_1570329_4 Belongs to the universal stress protein A family - - - 0.0000000000000002932 90.0
HKD2_k127_1570329_5 Nitroreductase - - - 0.0000439 46.0
HKD2_k127_158098_0 Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway K15521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 590.0
HKD2_k127_158098_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 436.0
HKD2_k127_158098_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 418.0
HKD2_k127_158098_3 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003146 248.0
HKD2_k127_158098_4 Appr-1'-p processing enzyme - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000001247 248.0
HKD2_k127_158098_5 MDMPI C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008504 249.0
HKD2_k127_158098_6 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000001539 240.0
HKD2_k127_158098_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000242 224.0
HKD2_k127_158098_8 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000001303 222.0
HKD2_k127_158098_9 Copper chaperone PCu(A)C - - - 0.00001137 57.0
HKD2_k127_1622635_0 GTP-binding protein TypA K06207 - - 2.72e-277 857.0
HKD2_k127_1622635_1 - - - - 0.0004679 46.0
HKD2_k127_1668112_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 611.0
HKD2_k127_1668112_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K01924,K02563 - 2.4.1.227,6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001996 261.0
HKD2_k127_1712345_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 479.0
HKD2_k127_1712345_1 MoeA domain protein domain I and II K00963,K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 459.0
HKD2_k127_1712345_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006431 290.0
HKD2_k127_1712345_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000003769 226.0
HKD2_k127_1712345_4 TIGRFAM molybdenum cofactor synthesis domain K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000001942 205.0
HKD2_k127_1712345_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000009424 185.0
HKD2_k127_1712345_6 Sortase family - - - 0.000000000000000000000000000000000000000000001184 184.0
HKD2_k127_1712345_7 PFAM GCN5-related N-acetyltransferase K03790 - 2.3.1.128 0.0000000000000203 83.0
HKD2_k127_1733434_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 2.311e-293 909.0
HKD2_k127_1733434_1 - - - - 0.00000000001635 70.0
HKD2_k127_1783804_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 3.405e-256 799.0
HKD2_k127_1783804_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 8.493e-248 779.0
HKD2_k127_1783804_2 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 293.0
HKD2_k127_1783804_3 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002716 252.0
HKD2_k127_1783804_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000001238 230.0
HKD2_k127_1783804_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000003092 159.0
HKD2_k127_1783804_6 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000007884 68.0
HKD2_k127_1804754_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.544e-238 745.0
HKD2_k127_1804754_1 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 519.0
HKD2_k127_1804754_2 Cation transport protein K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009629 509.0
HKD2_k127_1804754_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 429.0
HKD2_k127_1804754_4 PFAM Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 370.0
HKD2_k127_1804754_5 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 309.0
HKD2_k127_1804754_6 COG0569 K transport systems, NAD-binding component K03499 - - 0.000000000000000000000000000000000000000000000000000000000001762 213.0
HKD2_k127_1804754_7 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000008315 190.0
HKD2_k127_1804754_8 2'-5' RNA ligase superfamily K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000002438 168.0
HKD2_k127_1804754_9 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000000000000000000000000000000004803 144.0
HKD2_k127_181953_0 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 490.0
HKD2_k127_181953_1 FAD binding domain K05712 - 1.14.13.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 432.0
HKD2_k127_181953_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 386.0
HKD2_k127_1834965_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 8.783e-240 761.0
HKD2_k127_1834965_1 PFAM glycosyl transferase family 39 K00728 - 2.4.1.109 7.134e-230 721.0
HKD2_k127_1834965_10 CoA binding domain K06929 - - 0.000000000000000000000000000000000009874 153.0
HKD2_k127_1834965_11 Histidine kinase-like ATPases - - - 0.000003528 56.0
HKD2_k127_1834965_2 TOBE domain K02017,K02018 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 443.0
HKD2_k127_1834965_3 Capsule synthesis protein K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 416.0
HKD2_k127_1834965_4 TIGRFAM hydrolase, TatD family K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 387.0
HKD2_k127_1834965_5 PFAM binding-protein-dependent transport systems inner membrane component K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 380.0
HKD2_k127_1834965_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 344.0
HKD2_k127_1834965_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 322.0
HKD2_k127_1834965_8 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 304.0
HKD2_k127_1834965_9 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001316 280.0
HKD2_k127_1842781_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 369.0
HKD2_k127_1842781_1 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004735 251.0
HKD2_k127_1842781_2 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000003382 256.0
HKD2_k127_184731_0 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein K00366,K00392 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016002,GO:0016053,GO:0016491,GO:0016667,GO:0016673,GO:0019344,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.7.7.1,1.8.7.1 1.884e-281 873.0
HKD2_k127_184731_1 Ferredoxin--NADP reductase K21567 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 523.0
HKD2_k127_184731_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 500.0
HKD2_k127_184731_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000004299 258.0
HKD2_k127_184731_4 - - - - 0.000000000000000000000000000000000000000000000000008845 191.0
HKD2_k127_184731_5 sirohydrochlorin cobaltochelatase activity K03795,K06042 - 4.99.1.3,5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000001323 159.0
HKD2_k127_184731_6 Response regulator receiver - - - 0.0000000000000000000000000000000000000002415 163.0
HKD2_k127_184731_7 Transposase - - - 0.0000000002624 73.0
HKD2_k127_1875515_0 Belongs to the long-chain O-acyltransferase family K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 596.0
HKD2_k127_1875515_1 bacterial-type flagellum organization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 294.0
HKD2_k127_1875515_3 - - - - 0.000000000000000000000000000000000000000000000000000012 202.0
HKD2_k127_1875515_4 excisionase family - - - 0.00000000000000000000000000000002823 129.0
HKD2_k127_1875515_5 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000002132 125.0
HKD2_k127_1875515_6 PFAM Peptidoglycan-binding lysin domain - - - 0.0000000000000000000000000007552 124.0
HKD2_k127_1875515_7 - - - - 0.0000000000000000000000003817 117.0
HKD2_k127_1875515_8 CobQ/CobB/MinD/ParA nucleotide binding domain - - - 0.00000000000000000000009612 110.0
HKD2_k127_1875515_9 PFAM Peptidoglycan-binding lysin domain - - - 0.00000000000000000008934 100.0
HKD2_k127_1899425_0 PFAM ResB family protein K07399 - - 3.763e-230 725.0
HKD2_k127_1899425_1 cytochrome c biogenesis protein K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001381 278.0
HKD2_k127_1899425_2 Cytochrome c-type biogenesis protein - - - 0.0002281 52.0
HKD2_k127_1928318_0 histidine kinase HAMP region domain protein K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 341.0
HKD2_k127_1928318_1 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000004056 216.0
HKD2_k127_1928318_2 Response regulator receiver - - - 0.00000000000000000000000000000006071 136.0
HKD2_k127_1950278_0 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 294.0
HKD2_k127_1950278_1 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18958 GO:0001101,GO:0008150,GO:0010033,GO:0033993,GO:0042221,GO:0046677,GO:0050896,GO:0070542,GO:1901700 - 0.0000000000000000000000000000000000000004792 156.0
HKD2_k127_1950278_2 PFAM UvrD REP helicase K03657 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 0.00000000000000000005468 90.0
HKD2_k127_1951635_0 Bacterial Ig-like domain - - - 0.0 1043.0
HKD2_k127_1951635_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 593.0
HKD2_k127_1951635_10 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 341.0
HKD2_k127_1951635_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 299.0
HKD2_k127_1951635_12 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002722 271.0
HKD2_k127_1951635_13 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000657 262.0
HKD2_k127_1951635_14 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007962 264.0
HKD2_k127_1951635_15 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000248 265.0
HKD2_k127_1951635_16 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000002939 210.0
HKD2_k127_1951635_17 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000002613 192.0
HKD2_k127_1951635_18 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000002822 134.0
HKD2_k127_1951635_19 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.000000000000000000000008553 114.0
HKD2_k127_1951635_2 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 544.0
HKD2_k127_1951635_20 PFAM O-antigen polymerase - - - 0.00000000000000001702 89.0
HKD2_k127_1951635_21 Glycosyl transferases group 1 - - - 0.00000000000000006638 93.0
HKD2_k127_1951635_22 - - - - 0.00000000000000276 86.0
HKD2_k127_1951635_23 UDP binding domain K02472,K13015 - 1.1.1.136,1.1.1.336 0.000000000018 65.0
HKD2_k127_1951635_24 - - - - 0.00002914 55.0
HKD2_k127_1951635_25 Polysaccharide biosynthesis protein K03328,K16695 - - 0.00006654 53.0
HKD2_k127_1951635_3 response to copper ion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 509.0
HKD2_k127_1951635_4 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 531.0
HKD2_k127_1951635_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 500.0
HKD2_k127_1951635_6 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 419.0
HKD2_k127_1951635_7 Polysaccharide biosynthesis protein K03328,K16695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 372.0
HKD2_k127_1951635_8 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 357.0
HKD2_k127_1951635_9 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008569 357.0
HKD2_k127_1960828_0 PFAM ABC transporter K06158 - - 8.655e-271 841.0
HKD2_k127_1960828_1 Aminotransferase class-V - - - 1.079e-263 826.0
HKD2_k127_1960828_11 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000004091 152.0
HKD2_k127_1960828_12 positive regulation of growth - - - 0.0000000000000000000000000000001192 127.0
HKD2_k127_1960828_13 - - - - 0.000000000000000000000005913 108.0
HKD2_k127_1960828_14 PFAM plasmid K06218 - - 0.0000000000000000000004617 100.0
HKD2_k127_1960828_15 IrrE N-terminal-like domain - - - 0.0000000001188 66.0
HKD2_k127_1960828_16 - - - - 0.0000000003503 67.0
HKD2_k127_1960828_17 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0006163 49.0
HKD2_k127_1960828_2 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 2.601e-202 638.0
HKD2_k127_1960828_3 Circularly permuted ATP-grasp type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 563.0
HKD2_k127_1960828_4 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 487.0
HKD2_k127_1960828_5 Bacterial transglutaminase-like N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 425.0
HKD2_k127_1960828_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 370.0
HKD2_k127_1960828_7 Drug exporters of the RND superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002754 259.0
HKD2_k127_1960828_8 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000002355 236.0
HKD2_k127_1960828_9 Circularly permuted ATP-grasp type 2 - - - 0.000000000000000000000000000000000000000006247 173.0
HKD2_k127_1978289_0 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 516.0
HKD2_k127_1978289_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 395.0
HKD2_k127_1978289_2 4-coumarate--CoA - - - 0.0000000000000000001614 103.0
HKD2_k127_1978289_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000005072 57.0
HKD2_k127_1999464_0 Required for chromosome condensation and partitioning K03529 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 7.661e-318 998.0
HKD2_k127_1999464_1 nucleic acid binding OB-fold tRNA helicase-type K03655 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 4.33e-309 962.0
HKD2_k127_1999464_10 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000003384 120.0
HKD2_k127_1999464_11 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000005316 108.0
HKD2_k127_1999464_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K01007,K02078 - 2.7.9.2 0.0000001798 64.0
HKD2_k127_1999464_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 421.0
HKD2_k127_1999464_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 352.0
HKD2_k127_1999464_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000002261 247.0
HKD2_k127_1999464_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000296 248.0
HKD2_k127_1999464_6 Dak phosphatase K07030 - - 0.000000000000000000000000000000000000000000000000000000000000002679 229.0
HKD2_k127_1999464_7 Uncharacterized ACR, COG1399 K07040 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000001107 220.0
HKD2_k127_1999464_8 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000002157 215.0
HKD2_k127_1999464_9 Dak phosphatase K07030 - - 0.00000000000000000000000000000000000481 153.0
HKD2_k127_2022322_0 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 1.754e-214 678.0
HKD2_k127_2022322_1 PFAM penicillin-binding protein transpeptidase K05364 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 610.0
HKD2_k127_2022322_2 Serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 453.0
HKD2_k127_2022322_3 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 443.0
HKD2_k127_2022322_4 protein phosphatase 2C domain protein K20074 GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 0.0000000000000000000000119 108.0
HKD2_k127_2034926_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278,K00767 - 1.4.3.16,2.4.2.19 1.023e-245 783.0
HKD2_k127_2034926_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 5.584e-201 630.0
HKD2_k127_2034926_11 Belongs to the complex I 49 kDa subunit family K00333 - 1.6.5.3 0.00001206 47.0
HKD2_k127_2034926_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 409.0
HKD2_k127_2034926_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 384.0
HKD2_k127_2034926_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 376.0
HKD2_k127_2034926_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 338.0
HKD2_k127_2034926_6 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 308.0
HKD2_k127_2034926_7 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000006175 213.0
HKD2_k127_2034926_8 Methyltransferase domain - - - 0.000000000000000000000000000001079 131.0
HKD2_k127_2034926_9 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000002126 70.0
HKD2_k127_2069706_0 GMC oxidoreductase - - - 8.799e-278 877.0
HKD2_k127_2069706_1 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004282 270.0
HKD2_k127_2069706_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007784 224.0
HKD2_k127_2069706_3 Cytochrome b K03891 - - 0.00000000000000000000000000000000000000000000001109 192.0
HKD2_k127_2069706_4 Cytochrome c oxidase subunit IV - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000004675 103.0
HKD2_k127_2071478_0 Protein of unknown function, DUF255 K06888 - - 4.296e-281 874.0
HKD2_k127_2071478_1 TIGRFAM channel protein, hemolysin III family K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 308.0
HKD2_k127_2071478_2 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 315.0
HKD2_k127_2071478_3 - - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007711 279.0
HKD2_k127_2071478_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.0000000000000000000000000000000000464 137.0
HKD2_k127_2077540_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 584.0
HKD2_k127_2077540_1 pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 565.0
HKD2_k127_2077540_10 Domain of unknown function (DUF4407) - - - 0.00000000000000000000000000000000000000000000000000005139 205.0
HKD2_k127_2077540_11 RAMP superfamily - - - 0.0000000000000000000000000000000000000000004597 183.0
HKD2_k127_2077540_13 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000006116 139.0
HKD2_k127_2077540_14 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000001275 125.0
HKD2_k127_2077540_15 RAMP superfamily - - - 0.00000000000000000000001368 109.0
HKD2_k127_2077540_16 Transposase - - - 0.0000000000000000282 84.0
HKD2_k127_2077540_17 TIGRFAM CRISPR-associated protein, TIGR03984 family - - - 0.0000000000000001733 88.0
HKD2_k127_2077540_18 Acetyltransferase (GNAT) domain - - - 0.000000000000005491 79.0
HKD2_k127_2077540_19 cellulase activity K03332 - 3.2.1.80 0.000000000000005632 89.0
HKD2_k127_2077540_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 564.0
HKD2_k127_2077540_20 helicase - - - 0.0000000000003856 76.0
HKD2_k127_2077540_25 manually curated - - - 0.00005332 45.0
HKD2_k127_2077540_3 COG0659 Sulfate permease and related transporters (MFS superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 519.0
HKD2_k127_2077540_4 RAMP superfamily K19134 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 504.0
HKD2_k127_2077540_5 crispr-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 366.0
HKD2_k127_2077540_6 RAMP superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 383.0
HKD2_k127_2077540_8 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000004675 269.0
HKD2_k127_2077540_9 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001244 255.0
HKD2_k127_2077634_0 haloacid dehalogenase-like hydrolase K01533,K17686 - 3.6.3.4,3.6.3.54 2.243e-250 782.0
HKD2_k127_2077634_1 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 385.0
HKD2_k127_2077634_2 PFAM IstB-like ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008855 261.0
HKD2_k127_2077634_3 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000006874 60.0
HKD2_k127_2077634_4 manually curated - - - 0.00005332 45.0
HKD2_k127_2116258_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.043e-218 696.0
HKD2_k127_2116258_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 379.0
HKD2_k127_2116258_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000004158 66.0
HKD2_k127_211710_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 2.527e-227 711.0
HKD2_k127_211710_1 uracil-DNA glycosylase K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 363.0
HKD2_k127_211710_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001892 282.0
HKD2_k127_211710_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000006983 201.0
HKD2_k127_211710_4 Amino acid-binding act domain protein K03567 - - 0.000000000000000000000000000000000000009824 152.0
HKD2_k127_2120342_0 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 538.0
HKD2_k127_2120342_1 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 309.0
HKD2_k127_2120342_2 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008234 284.0
HKD2_k127_212640_0 DEAD DEAH box helicase domain protein K03724 - - 4.37e-321 997.0
HKD2_k127_212640_1 Belongs to the CinA family K03742,K03743 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 582.0
HKD2_k127_212640_2 DNA translocase ftsK K03466 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 557.0
HKD2_k127_212640_3 Evidence 2b Function of strongly homologous gene K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 359.0
HKD2_k127_212640_4 Phage shock protein A, PspA K03969 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 317.0
HKD2_k127_212640_5 CDP-alcohol phosphatidyltransferase K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000001424 231.0
HKD2_k127_212640_6 Domain of unknown function (DUF4115) - - - 0.000000000000000000000000000000000000000000000000000000000007141 217.0
HKD2_k127_212640_7 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000002798 215.0
HKD2_k127_212640_9 PFAM helix-turn-helix domain protein - GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000147 128.0
HKD2_k127_2142431_0 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000006749 250.0
HKD2_k127_2142431_1 Domain of unknown function (DUF1929) - - - 0.000000000000000000000000000000000000000001259 162.0
HKD2_k127_2161454_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1167.0
HKD2_k127_2161454_1 TIGRFAM Dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 1.576e-207 657.0
HKD2_k127_2161454_10 Transcription factor WhiB K18955 - - 0.0000000000000000000001899 104.0
HKD2_k127_2161454_11 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000127 93.0
HKD2_k127_2161454_12 - - - - 0.000001017 58.0
HKD2_k127_2161454_13 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0001171 48.0
HKD2_k127_2161454_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 576.0
HKD2_k127_2161454_3 PFAM Transketolase central region K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 548.0
HKD2_k127_2161454_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 451.0
HKD2_k127_2161454_5 RNA polymerase sigma factor K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 359.0
HKD2_k127_2161454_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 342.0
HKD2_k127_2161454_7 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000002552 189.0
HKD2_k127_2161454_8 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000001408 129.0
HKD2_k127_2161454_9 anti-sigma factor - GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.000000000000000000000000004808 126.0
HKD2_k127_2163394_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 541.0
HKD2_k127_2163394_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 GO:0008150,GO:0040007 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 509.0
HKD2_k127_2163394_2 HAD-superfamily subfamily IB hydrolase, TIGR01490 - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 411.0
HKD2_k127_2163394_3 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 326.0
HKD2_k127_2163394_4 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000002842 241.0
HKD2_k127_2163394_5 PFAM Glutaredoxin 2 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000002761 113.0
HKD2_k127_2175537_0 transport K02027 - - 0.0000000000000000000000000000000000000000000000000000008338 202.0
HKD2_k127_2175537_1 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.00000000000000000000000000000000001508 151.0
HKD2_k127_2175537_2 transport K02027 - - 0.000001128 54.0
HKD2_k127_2202886_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5.361e-308 960.0
HKD2_k127_2202886_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.148e-206 654.0
HKD2_k127_2202886_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000007981 124.0
HKD2_k127_2202886_11 PFAM plasmid stabilization system - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000002026 109.0
HKD2_k127_2202886_12 Glycosyl transferase family 2 - - - 0.0000000000000795 81.0
HKD2_k127_2202886_2 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 502.0
HKD2_k127_2202886_3 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 395.0
HKD2_k127_2202886_4 Glycosyl transferase family group 2 K00752 - 2.4.1.212 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 357.0
HKD2_k127_2202886_5 PFAM glycoside hydrolase family 25 K07273 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009585 325.0
HKD2_k127_2202886_6 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002246 272.0
HKD2_k127_2202886_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007479 237.0
HKD2_k127_2202886_8 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000008774 190.0
HKD2_k127_2202886_9 Antitoxin component of a toxin-antitoxin (TA) module - GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000002829 134.0
HKD2_k127_2202941_0 FAD dependent oxidoreductase - - - 1.179e-217 689.0
HKD2_k127_2202941_1 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 259.0
HKD2_k127_2202941_2 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000008478 164.0
HKD2_k127_2202941_3 PFAM Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000002507 153.0
HKD2_k127_2202941_4 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000594 136.0
HKD2_k127_2202941_5 antisigma factor binding K03090,K04749,K06378 - - 0.0000226 53.0
HKD2_k127_2221931_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 602.0
HKD2_k127_2221931_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0001879 47.0
HKD2_k127_2233338_0 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 406.0
HKD2_k127_2233338_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 374.0
HKD2_k127_2233338_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000007148 128.0
HKD2_k127_2233338_3 PFAM NLP P60 protein K21471 - - 0.0000000000000000000000000000001761 137.0
HKD2_k127_2233338_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000004282 81.0
HKD2_k127_225127_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 5.765e-235 747.0
HKD2_k127_225127_1 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 7.67e-199 669.0
HKD2_k127_225127_10 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000001164 258.0
HKD2_k127_225127_11 ABC transporter K02003 - - 0.0000000000000000000001437 103.0
HKD2_k127_225127_12 ATP-grasp domain - - - 0.00000000000000000002966 99.0
HKD2_k127_225127_13 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000009708 100.0
HKD2_k127_225127_14 Universal stress protein family - - - 0.0000000000000000008032 94.0
HKD2_k127_225127_17 TRANSCRIPTIONal - - - 0.0002932 45.0
HKD2_k127_225127_2 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 539.0
HKD2_k127_225127_3 Glycoside hydrolase 15-related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 511.0
HKD2_k127_225127_4 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 434.0
HKD2_k127_225127_5 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 419.0
HKD2_k127_225127_6 Glycoside hydrolase 15-related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 383.0
HKD2_k127_225127_7 Two component transcriptional regulator, LuxR family K07695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 297.0
HKD2_k127_225127_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006384 267.0
HKD2_k127_225127_9 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005226 254.0
HKD2_k127_2269260_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1269.0
HKD2_k127_2269260_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000000000000000000601 216.0
HKD2_k127_2269260_2 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000000000009778 138.0
HKD2_k127_2269260_3 PFAM phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.000000000000002233 85.0
HKD2_k127_231545_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 398.0
HKD2_k127_231545_1 - - - - 0.000000000000000001249 99.0
HKD2_k127_231801_0 Amino acid permease - - - 1.646e-309 960.0
HKD2_k127_231801_1 amino acid - - - 3.694e-247 785.0
HKD2_k127_231801_2 PFAM TrkA-N domain protein K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 317.0
HKD2_k127_231801_3 PFAM TrkA-N domain protein K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008954 305.0
HKD2_k127_231801_4 Protein of unknown function (DUF3159) - - - 0.00000000000000000000000000000000000000000000000000000000000008242 222.0
HKD2_k127_231801_5 Nucleic acid binding, OB-fold, tRNA - - - 0.00000000000000000000000000000000000001838 160.0
HKD2_k127_231801_6 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.00000000000000000000000001038 121.0
HKD2_k127_231801_7 Protein of unknown function (DUF3710) - - - 0.000000000000000000000001796 104.0
HKD2_k127_231801_8 - - - - 0.0000000000000007214 83.0
HKD2_k127_2341092_0 hydrolase of the alpha beta K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 313.0
HKD2_k127_2341092_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 319.0
HKD2_k127_2341092_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 310.0
HKD2_k127_2341092_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000097 262.0
HKD2_k127_2341092_4 negative regulation of DNA recombination K07456 - - 0.0000008475 53.0
HKD2_k127_236738_0 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 310.0
HKD2_k127_236738_1 Periplasmic binding protein K01999 - - 0.00000000000000000000008092 101.0
HKD2_k127_236738_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000001782 89.0
HKD2_k127_236738_3 DNA-binding transcription factor activity K03655,K07506 - 3.6.4.12 0.000000000004366 74.0
HKD2_k127_244623_0 lacI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 365.0
HKD2_k127_244623_1 Glycosyl hydrolase family 32 K01193 - 3.2.1.26 0.0000000000000000000000000000000000000000000000000000000000006219 225.0
HKD2_k127_248648_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 9.181e-252 786.0
HKD2_k127_248648_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 544.0
HKD2_k127_248648_10 Putative transposase DNA-binding domain - - - 0.0001065 51.0
HKD2_k127_248648_2 Putative transposase DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 514.0
HKD2_k127_248648_3 TIGRFAM 2-oxoglutarate dehydrogenase, E1 K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 421.0
HKD2_k127_248648_4 Involved in chromosome - GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009405,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044315,GO:0044419,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 385.0
HKD2_k127_248648_5 Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 292.0
HKD2_k127_248648_6 PFAM transposase IS200-family protein K07491 - - 0.000000000000000000000000000000000000000000000000001136 186.0
HKD2_k127_248648_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000008444 166.0
HKD2_k127_248648_8 - - - - 0.0000000000000000000000000000000003116 138.0
HKD2_k127_248648_9 - - - - 0.000000000000000000000003027 103.0
HKD2_k127_2554462_0 PFAM Aldehyde dehydrogenase K00294 - 1.2.1.88 3.239e-259 812.0
HKD2_k127_2554462_1 type II secretion system protein E K02283 - - 3.595e-211 667.0
HKD2_k127_2554462_10 antisigma factor binding - - - 0.000000000000000000000000000000000000000000000003595 190.0
HKD2_k127_2554462_11 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000000002462 164.0
HKD2_k127_2554462_12 Protein of unknown function (DUF3072) - - - 0.000000000000000000001777 98.0
HKD2_k127_2554462_13 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000004855 86.0
HKD2_k127_2554462_14 TadE-like protein - - - 0.0000000000000001563 86.0
HKD2_k127_2554462_15 - - - - 0.00000000000002403 75.0
HKD2_k127_2554462_16 rRNA binding - - - 0.000002495 58.0
HKD2_k127_2554462_2 Belongs to the peptidase S1B family K01183,K03791,K22278 - 3.2.1.14,3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 424.0
HKD2_k127_2554462_3 Type II secretion system K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 409.0
HKD2_k127_2554462_4 Type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 405.0
HKD2_k127_2554462_5 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 387.0
HKD2_k127_2554462_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 323.0
HKD2_k127_2554462_7 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 267.0
HKD2_k127_2554462_8 - - - - 0.00000000000000000000000000000000000000000000000006456 183.0
HKD2_k127_2554462_9 - - - - 0.0000000000000000000000000000000000000000000000007781 179.0
HKD2_k127_2557315_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 - 4.787e-217 694.0
HKD2_k127_2557315_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 582.0
HKD2_k127_2557315_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 535.0
HKD2_k127_2557315_3 ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000003679 234.0
HKD2_k127_2557315_4 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000000005402 152.0
HKD2_k127_2557315_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000005806 134.0
HKD2_k127_2564910_0 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 588.0
HKD2_k127_2564910_1 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 482.0
HKD2_k127_2564910_10 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0001157 47.0
HKD2_k127_2564910_2 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 399.0
HKD2_k127_2564910_3 Glycosyltransferase family 87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 349.0
HKD2_k127_2564910_4 anti-sigma regulatory factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 303.0
HKD2_k127_2564910_5 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 302.0
HKD2_k127_2564910_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 285.0
HKD2_k127_2564910_7 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000002318 163.0
HKD2_k127_2564910_8 - - - - 0.0000000000000000000000000002541 118.0
HKD2_k127_2570985_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.797e-220 698.0
HKD2_k127_2570985_1 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 600.0
HKD2_k127_2570985_2 TIGRFAM acetylornithine and succinylornithine K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 561.0
HKD2_k127_2570985_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 506.0
HKD2_k127_2570985_4 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000002866 221.0
HKD2_k127_2570985_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000002524 173.0
HKD2_k127_2572970_0 ABC transporter K01990 - - 9.482e-225 728.0
HKD2_k127_2572970_1 Cysteine synthase K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 573.0
HKD2_k127_2572970_10 PFAM Mov34 MPN PAD-1 family K21140 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.13.1.6 0.00000000000000000000000000000000000000000000000000000000001942 224.0
HKD2_k127_2572970_11 Domain of unknown function (DUF2017) - - - 0.00000000000000000000000000000000000000000000000006564 186.0
HKD2_k127_2572970_12 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000001197 153.0
HKD2_k127_2572970_13 ThiS family K03636 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000003141 158.0
HKD2_k127_2572970_14 PIN domain K07064 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.000000000000000000000001039 108.0
HKD2_k127_2572970_15 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000002641 108.0
HKD2_k127_2572970_16 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000006937 85.0
HKD2_k127_2572970_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 539.0
HKD2_k127_2572970_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 417.0
HKD2_k127_2572970_4 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 379.0
HKD2_k127_2572970_5 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 332.0
HKD2_k127_2572970_6 Short-chain alcohol dehydrogenase K16066 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.381 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001165 289.0
HKD2_k127_2572970_7 short chain dehydrogenase K00218 - 1.3.1.33 0.0000000000000000000000000000000000000000000000000000000000000000009563 237.0
HKD2_k127_2572970_8 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000433 229.0
HKD2_k127_2572970_9 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000007108 220.0
HKD2_k127_2583748_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 460.0
HKD2_k127_2583748_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000002651 170.0
HKD2_k127_2583748_2 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000001564 127.0
HKD2_k127_2583910_0 CRISPR-associated helicase Cas3 - - - 5.653e-236 767.0
HKD2_k127_2583910_1 threonine--tRNA ligase K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 557.0
HKD2_k127_2583910_10 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000311 220.0
HKD2_k127_2583910_11 glyoxalase bleomycin resistance protein dioxygenase - GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 - 0.00000000000000000000000000000000000000000000000000000000002264 220.0
HKD2_k127_2583910_12 transcriptional regulator K03892 - - 0.000000000000000000000000000000000000000000003433 166.0
HKD2_k127_2583910_13 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.0000000000000000000000000000001864 127.0
HKD2_k127_2583910_14 Domain of unknown function (DUF4383) - - - 0.0000000000000000000000000000004945 141.0
HKD2_k127_2583910_15 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000001674 125.0
HKD2_k127_2583910_16 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.000000000000000000000000000001984 121.0
HKD2_k127_2583910_17 thiolester hydrolase activity - - - 0.000000000000000000000000000007082 131.0
HKD2_k127_2583910_18 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000177 121.0
HKD2_k127_2583910_19 phosphinothricin N-acetyltransferase activity K03827 - - 0.0000000000000000000000488 114.0
HKD2_k127_2583910_2 CRISPR-associated autoregulator DevR family K19075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 473.0
HKD2_k127_2583910_20 YCII-related domain - - - 0.000000000000002326 89.0
HKD2_k127_2583910_21 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000004509 77.0
HKD2_k127_2583910_22 - - GO:0008150,GO:0009605,GO:0009607,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - 0.00000000000007886 72.0
HKD2_k127_2583910_24 TIGRFAM proline-specific peptidases, Bacillus coagulans-type subfamily K01259 - 3.4.11.5 0.00000002359 65.0
HKD2_k127_2583910_25 - - - - 0.00002837 57.0
HKD2_k127_2583910_26 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.0001846 49.0
HKD2_k127_2583910_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 404.0
HKD2_k127_2583910_4 CRISPR associated protein Cas6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 332.0
HKD2_k127_2583910_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 332.0
HKD2_k127_2583910_6 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 301.0
HKD2_k127_2583910_7 luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001349 295.0
HKD2_k127_2583910_8 defense response to virus K07012,K19090 - - 0.000000000000000000000000000000000000000000000000000000000000000000001273 245.0
HKD2_k127_2583910_9 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.00000000000000000000000000000000000000000000000000000000000000000006752 234.0
HKD2_k127_2588416_0 PFAM Aminotransferase class-III K01845 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 5.4.3.8 5.993e-218 683.0
HKD2_k127_2588416_1 phosphoglycerate mutase - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 304.0
HKD2_k127_2588416_2 Alkyl hydroperoxide reductase Thiol specific antioxidant K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000003679 234.0
HKD2_k127_2588416_3 peptidase C60 sortase A and B - - - 0.000000000000000000000000000000000000000007061 159.0
HKD2_k127_2588416_4 cytochrome c biogenesis protein K06196 - - 0.000000000000000000000000001765 124.0
HKD2_k127_2599316_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0008150,GO:0040007 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 614.0
HKD2_k127_2599316_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 512.0
HKD2_k127_2599316_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 384.0
HKD2_k127_2599316_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 0.00000000000000000000000000006666 131.0
HKD2_k127_2601181_0 isochorismatase activity K01252,K20261 GO:0000287,GO:0003674,GO:0003824,GO:0004463,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008908,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0016787,GO:0016801,GO:0016803,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0019842,GO:0031177,GO:0033218,GO:0034641,GO:0036094,GO:0042802,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0046872,GO:0047527,GO:0048037,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072341,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.3.2.1,3.3.2.15,6.3.2.14 0.000000000000000000000000000005334 132.0
HKD2_k127_2601181_1 required for the transposition of insertion element IS2404 - - - 0.000005682 48.0
HKD2_k127_2607929_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 422.0
HKD2_k127_2607929_1 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 430.0
HKD2_k127_2607929_2 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 317.0
HKD2_k127_2607929_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001036 256.0
HKD2_k127_2607929_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000001227 240.0
HKD2_k127_2607929_5 COG1961 Site-specific recombinases, DNA invertase Pin homologs K06400 - - 0.000000000000005897 76.0
HKD2_k127_2625111_0 Radical SAM K18563 - - 1.229e-234 744.0
HKD2_k127_2625111_1 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 457.0
HKD2_k127_2625111_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002656 275.0
HKD2_k127_2625111_3 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000005691 239.0
HKD2_k127_2625111_4 membrane - - - 0.000000000000000000000000000000000000000000000000000000000001113 233.0
HKD2_k127_2625111_5 - - - - 0.00000000000000000000000000000000000000000000009334 176.0
HKD2_k127_2625111_6 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000277 158.0
HKD2_k127_2625111_7 Short chain dehydrogenase - - - 0.000000000000000006066 86.0
HKD2_k127_2625111_8 Methyltransferase type 11 - - - 0.0000000000000001817 79.0
HKD2_k127_2648108_0 geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 508.0
HKD2_k127_2648108_1 CBS domain containing protein K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 505.0
HKD2_k127_2648108_10 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000003565 57.0
HKD2_k127_2648108_12 - - - - 0.0000001076 59.0
HKD2_k127_2648108_13 HicA toxin of bacterial toxin-antitoxin, - - - 0.000001833 53.0
HKD2_k127_2648108_14 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0002665 52.0
HKD2_k127_2648108_15 - - - - 0.0005907 48.0
HKD2_k127_2648108_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 477.0
HKD2_k127_2648108_3 Tryptophanyl-tRNA synthetase K01867 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 474.0
HKD2_k127_2648108_4 PFAM ribonuclease K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 383.0
HKD2_k127_2648108_5 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000006275 266.0
HKD2_k127_2648108_6 2'-5' RNA ligase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000003893 241.0
HKD2_k127_2648108_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000002802 172.0
HKD2_k127_2648108_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000001284 127.0
HKD2_k127_2648108_9 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000008425 118.0
HKD2_k127_2651763_0 PFAM glycosyl transferase, family 35 K00688 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1 0.0 1405.0
HKD2_k127_2651763_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 7.289e-253 799.0
HKD2_k127_2651763_10 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000001942 121.0
HKD2_k127_2651763_11 - - - - 0.000000000000000000000005982 102.0
HKD2_k127_2651763_12 Protein of unknown function, DUF485 - - - 0.000000000000000000005832 100.0
HKD2_k127_2651763_13 - - - - 0.00000000000002073 79.0
HKD2_k127_2651763_2 Pfam:Arch_ATPase K06921 - - 3.535e-220 691.0
HKD2_k127_2651763_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 6.288e-203 646.0
HKD2_k127_2651763_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 554.0
HKD2_k127_2651763_5 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 316.0
HKD2_k127_2651763_6 Histidine kinase K02478 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 308.0
HKD2_k127_2651763_7 Response regulator of the LytR AlgR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001074 276.0
HKD2_k127_2651763_8 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000003705 258.0
HKD2_k127_2651763_9 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000002782 197.0
HKD2_k127_2655040_0 - - - - 0.00000000000000000000000000000000000000001968 158.0
HKD2_k127_2655040_1 Belongs to the 'phage' integrase family - - - 0.0000000000007448 77.0
HKD2_k127_2655040_2 Cysteine-rich secretory protein family - - - 0.000000002856 58.0
HKD2_k127_2663302_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1388.0
HKD2_k127_2663302_1 Heat shock 70 kDa protein K04043 - - 0.0 1063.0
HKD2_k127_2663302_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 555.0
HKD2_k127_2663302_3 PFAM MMPL domain protein K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 467.0
HKD2_k127_2663302_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000007731 255.0
HKD2_k127_2663302_5 transcriptional regulator, MerR K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000004773 211.0
HKD2_k127_2663302_6 - - - - 0.0000000000000000000000000000000000000000000001724 183.0
HKD2_k127_2663302_7 PFAM MMPL domain protein K06994 - - 0.00000000000000000000000000000000000000001756 171.0
HKD2_k127_2663302_8 PFAM MMPL domain protein K06994 - - 0.00000000000000000000000000001097 121.0
HKD2_k127_2663302_9 - - - - 0.000000000000000000000000001175 123.0
HKD2_k127_2673217_0 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 443.0
HKD2_k127_2673217_1 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 432.0
HKD2_k127_2673217_10 Belongs to the Fur family K03711,K09825 - - 0.00000000000000000000000000000000000000000004242 181.0
HKD2_k127_2673217_12 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000000001541 108.0
HKD2_k127_2673217_13 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000001179 105.0
HKD2_k127_2673217_14 - - - - 0.0003772 49.0
HKD2_k127_2673217_2 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 400.0
HKD2_k127_2673217_3 Polyphosphate kinase 2 (PPK2) K22468 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005525,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006183,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030808,GO:0031323,GO:0031326,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046777,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051704,GO:0055086,GO:0062012,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0080090,GO:0090407,GO:0097159,GO:0097367,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 398.0
HKD2_k127_2673217_4 Small subunit K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 327.0
HKD2_k127_2673217_5 May play a role in the intracellular transport of hydrophobic ligands - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007114 261.0
HKD2_k127_2673217_6 PFAM aldo keto reductase K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000006521 258.0
HKD2_k127_2673217_7 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000001607 263.0
HKD2_k127_2673217_8 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000000000000007475 200.0
HKD2_k127_2673217_9 transcriptional regulator, XRE family - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000005739 180.0
HKD2_k127_2680683_0 PFAM glycosyl transferase, family 51 - - - 1.866e-254 804.0
HKD2_k127_2689324_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.353e-239 753.0
HKD2_k127_2689324_1 PFAM Glycosyl transferase, group 1 K13668 GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 572.0
HKD2_k127_2689324_10 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000008277 187.0
HKD2_k127_2689324_11 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000006098 171.0
HKD2_k127_2689324_12 - - - - 0.00000000000000000000000001641 117.0
HKD2_k127_2689324_13 - - - - 0.0000000000000000004188 89.0
HKD2_k127_2689324_15 Golgi phosphoprotein 3 (GPP34) - - - 0.00002054 57.0
HKD2_k127_2689324_2 Pyridoxal-dependent decarboxylase conserved domain K01580 - 4.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 526.0
HKD2_k127_2689324_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 500.0
HKD2_k127_2689324_4 YacP-like NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 485.0
HKD2_k127_2689324_5 PFAM ROK family protein K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 452.0
HKD2_k127_2689324_6 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 426.0
HKD2_k127_2689324_7 LOR/SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 376.0
HKD2_k127_2689324_8 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007687 286.0
HKD2_k127_2689324_9 Protein of unknown function (DUF1345) - - - 0.0000000000000000000000000000000000000000000000000000000000000008648 227.0
HKD2_k127_2697523_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0 1224.0
HKD2_k127_2697523_1 - - - - 0.00000000000000000000000000001084 136.0
HKD2_k127_2697523_2 short chain dehydrogenase K00218 - 1.3.1.33 0.00000000000000000000000004885 109.0
HKD2_k127_2700677_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.8.1.4 3.849e-211 673.0
HKD2_k127_2700677_1 Biotin carboxylase K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 397.0
HKD2_k127_2700677_2 PFAM AIG2 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000209 246.0
HKD2_k127_2700677_3 Family of unknown function (DUF5313) - - - 0.00000000000000000000000000000000000000000001901 164.0
HKD2_k127_2729957_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 488.0
HKD2_k127_2729957_1 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 304.0
HKD2_k127_2729957_2 xylan catabolic process K03932 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004135 269.0
HKD2_k127_2729957_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000006112 244.0
HKD2_k127_2729957_4 Conserved TM helix - - - 0.00000000000000000000000000000000000000000000000000000000001775 237.0
HKD2_k127_2729957_5 - - - - 0.0000000000000000000000000000000000000000000000000000003158 204.0
HKD2_k127_2729957_8 Transposase DDE domain - - - 0.0000000001375 61.0
HKD2_k127_2775838_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 599.0
HKD2_k127_2775838_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 377.0
HKD2_k127_2775838_2 Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters - GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000007659 203.0
HKD2_k127_2775838_3 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.000000000000000000000000000000000000007132 147.0
HKD2_k127_2775838_4 FxsA cytoplasmic membrane protein K07113 - - 0.0000000000000000000000000000001039 129.0
HKD2_k127_2775838_5 peptide-methionine (R)-S-oxide reductase activity - - - 0.0000000000000000287 89.0
HKD2_k127_2777365_0 4Fe-4S dicluster domain - - - 0.0 1068.0
HKD2_k127_2777365_1 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 472.0
HKD2_k127_2777365_10 Inositol monophosphatase family K01092,K05602 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000002541 132.0
HKD2_k127_2777365_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000002931 119.0
HKD2_k127_2777365_12 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000002285 82.0
HKD2_k127_2777365_13 Histidine kinase - - - 0.00000000000000006929 90.0
HKD2_k127_2777365_16 Aminotransferase class v - - - 0.00000000241 59.0
HKD2_k127_2777365_17 haloacid dehalogenase K01560 - 3.8.1.2 0.000000002526 68.0
HKD2_k127_2777365_18 DNA excision - - - 0.00000005386 58.0
HKD2_k127_2777365_19 CHASE3 domain - - - 0.00000511 58.0
HKD2_k127_2777365_2 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 336.0
HKD2_k127_2777365_3 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 295.0
HKD2_k127_2777365_4 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000007997 243.0
HKD2_k127_2777365_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000001059 224.0
HKD2_k127_2777365_6 SMART helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000523 203.0
HKD2_k127_2777365_7 stage II sporulation - - - 0.00000000000000000000000000000000000000000000000006635 198.0
HKD2_k127_2777365_8 - - - - 0.0000000000000000000000000000000000000000000002345 184.0
HKD2_k127_2777365_9 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000008634 140.0
HKD2_k127_2778903_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 440.0
HKD2_k127_2778903_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000905 412.0
HKD2_k127_2778903_2 - - - - 0.000000000000000000000000000000000000000000001976 169.0
HKD2_k127_2778903_4 Belongs to the 'phage' integrase family - - - 0.000000000000000000005429 93.0
HKD2_k127_2778903_5 PFAM Integrase catalytic region K07482 - - 0.000000184 56.0
HKD2_k127_2778903_7 recombinase activity - - - 0.0002478 46.0
HKD2_k127_2779512_0 PFAM transglutaminase domain protein - - - 1.508e-194 641.0
HKD2_k127_2779512_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 478.0
HKD2_k127_2779512_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 435.0
HKD2_k127_2779512_3 Protein of unknown function (DUF3040) - - - 0.0000000000000000000000000000000000000000000000003042 179.0
HKD2_k127_2779512_4 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000003776 99.0
HKD2_k127_2779512_5 DDE superfamily endonuclease - - - 0.00002976 46.0
HKD2_k127_2783133_0 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 462.0
HKD2_k127_2783133_1 Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway K15525 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016137,GO:0016138,GO:0016787,GO:0016810,GO:0016811,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 3.5.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 411.0
HKD2_k127_2783133_2 peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 337.0
HKD2_k127_2783133_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 299.0
HKD2_k127_2783133_4 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000009478 190.0
HKD2_k127_2783133_5 peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000004207 130.0
HKD2_k127_2783133_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000008336 128.0
HKD2_k127_2783133_8 Flavin reductase like domain - - - 0.000000000002665 68.0
HKD2_k127_2785350_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 448.0
HKD2_k127_2785350_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 363.0
HKD2_k127_2785350_2 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 342.0
HKD2_k127_2785350_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004983 276.0
HKD2_k127_2785350_4 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002098 253.0
HKD2_k127_2785350_5 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000002934 216.0
HKD2_k127_2785350_6 isochorismatase activity K01252,K20261 GO:0000287,GO:0003674,GO:0003824,GO:0004463,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008908,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0016787,GO:0016801,GO:0016803,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0019842,GO:0031177,GO:0033218,GO:0034641,GO:0036094,GO:0042802,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0046872,GO:0047527,GO:0048037,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072341,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.3.2.1,3.3.2.15,6.3.2.14 0.00000000000003107 74.0
HKD2_k127_2785396_0 Imelysin K07224 - - 1.612e-235 747.0
HKD2_k127_2785396_1 Dyp-type peroxidase family K16301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 528.0
HKD2_k127_2785396_2 PFAM iron dependent repressor K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002019 273.0
HKD2_k127_2785396_3 Protein of unknown function (DUF3039) - - - 0.0000000000000000000000000000002749 127.0
HKD2_k127_2785396_4 Putative restriction endonuclease - - - 0.0000000000000000000000000001704 127.0
HKD2_k127_2785396_5 PAS domain - - - 0.000000000000000004536 98.0
HKD2_k127_2790618_0 PFAM Adenosine AMP deaminase K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 5.135e-196 616.0
HKD2_k127_2790618_1 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 512.0
HKD2_k127_2790618_2 uracil phosphoribosyltransferase K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 293.0
HKD2_k127_2790618_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000001972 231.0
HKD2_k127_2790618_4 TIGRFAM Pyrimidine-nucleoside phosphorylase K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000152 164.0
HKD2_k127_2859682_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 5.46e-255 802.0
HKD2_k127_2859682_1 - - - - 0.0000002007 55.0
HKD2_k127_2899183_0 ABC transporter transmembrane region K02021,K06147,K16786,K16787 - - 1.402e-245 794.0
HKD2_k127_2899183_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 3.208e-199 642.0
HKD2_k127_2899183_2 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 527.0
HKD2_k127_2899183_3 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 449.0
HKD2_k127_2899183_4 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 328.0
HKD2_k127_2899183_5 Protein of unknown function (DUF1152) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001247 261.0
HKD2_k127_2899183_6 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 GO:0008150,GO:0040007 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000003688 223.0
HKD2_k127_2899183_7 Trp biosynthesis associated, transmembrane protein, Oprn Chp - - - 0.0000000000000000000000000000000000000000000000000008921 196.0
HKD2_k127_2899183_8 integral membrane protein - - - 0.000000006051 59.0
HKD2_k127_2931209_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 0.0 1127.0
HKD2_k127_2931209_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 620.0
HKD2_k127_2931209_10 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000001328 116.0
HKD2_k127_2931209_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000003446 104.0
HKD2_k127_2931209_12 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000003628 83.0
HKD2_k127_2931209_13 Belongs to the ParB family K03497 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - 0.000000000001 74.0
HKD2_k127_2931209_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 559.0
HKD2_k127_2931209_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 489.0
HKD2_k127_2931209_4 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 473.0
HKD2_k127_2931209_5 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 466.0
HKD2_k127_2931209_6 PFAM 60 kDa inner membrane insertion protein K03217 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 411.0
HKD2_k127_2931209_7 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000005297 233.0
HKD2_k127_2931209_8 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.00000000000000000000000000000000000000000000000000000000000000002589 231.0
HKD2_k127_2931209_9 Protein of unknown function (DUF721) - - - 0.000000000000000000000000000000000000000000000000006706 199.0
HKD2_k127_2955045_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 5.45e-253 790.0
HKD2_k127_2955045_1 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 397.0
HKD2_k127_2955045_2 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 340.0
HKD2_k127_2955045_3 Putative peptidoglycan binding domain K17733 - - 0.000000000000000000000000000000000000009032 153.0
HKD2_k127_2955045_4 PspC domain - - - 0.0000000000000000000000000000002677 133.0
HKD2_k127_2955045_5 - - - - 0.000000000000000000001446 103.0
HKD2_k127_3005677_0 Squalene--hopene cyclase K06045 - 4.2.1.129,5.4.99.17 1.183e-300 932.0
HKD2_k127_3005677_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 624.0
HKD2_k127_3005677_10 Transposase DDE domain - - - 0.0000000001891 61.0
HKD2_k127_3005677_2 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 582.0
HKD2_k127_3005677_3 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 552.0
HKD2_k127_3005677_4 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 447.0
HKD2_k127_3005677_5 phytoene synthase K02291 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 379.0
HKD2_k127_3005677_6 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 392.0
HKD2_k127_3005677_7 PFAM Squalene phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 329.0
HKD2_k127_3005677_8 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000008949 209.0
HKD2_k127_3005677_9 - - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000004298 87.0
HKD2_k127_3014164_0 sugar phosphate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 373.0
HKD2_k127_3014164_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 354.0
HKD2_k127_3014164_2 GDP-mannose 4,6 dehydratase K20432 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007711 286.0
HKD2_k127_3014164_3 glycosyl transferase family K20436 - 2.5.1.135 0.00000000000000000000000000000000000000000000000000000000000000000000001264 250.0
HKD2_k127_3014164_4 PFAM Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000004706 147.0
HKD2_k127_3017512_0 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 490.0
HKD2_k127_3017512_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 346.0
HKD2_k127_3017512_2 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 332.0
HKD2_k127_3017512_3 - - - - 0.00000000000000000000000000000000000000000001248 168.0
HKD2_k127_3017512_4 - - - - 0.0000000000000000004907 90.0
HKD2_k127_3017616_0 FAD dependent oxidoreductase - - - 2.114e-214 674.0
HKD2_k127_3017616_1 Polysaccharide pyruvyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 414.0
HKD2_k127_3017616_2 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 359.0
HKD2_k127_3017616_3 N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 331.0
HKD2_k127_3017616_4 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000001039 198.0
HKD2_k127_3017616_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000003863 186.0
HKD2_k127_3017616_6 - - - - 0.000000000000000000000000000000000000000000000000004071 198.0
HKD2_k127_3017616_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000003254 136.0
HKD2_k127_3017616_8 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000002619 93.0
HKD2_k127_3017616_9 toxin-antitoxin pair type II binding K19159 - - 0.0000008616 54.0
HKD2_k127_3017725_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 1.944e-210 674.0
HKD2_k127_3017725_1 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 557.0
HKD2_k127_3017725_10 DNA polymerase LigD - - - 0.000000000000000000000000000009562 121.0
HKD2_k127_3017725_11 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00000000000000000000000006173 111.0
HKD2_k127_3017725_12 Clp amino terminal domain, pathogenicity island component K03696 - - 0.00000000000000000000102 103.0
HKD2_k127_3017725_13 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000000000000471 78.0
HKD2_k127_3017725_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 564.0
HKD2_k127_3017725_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 513.0
HKD2_k127_3017725_4 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 508.0
HKD2_k127_3017725_5 Protein of unknown function (DUF4012) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 455.0
HKD2_k127_3017725_6 PFAM Chlorite dismutase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 383.0
HKD2_k127_3017725_7 Protein of unknown function (DUF3000) - - - 0.00000000000000000000000000000000000000000000000000000000000000005189 229.0
HKD2_k127_3017725_8 Recombinase - - - 0.0000000000000000000000000000000000000000000000000000000000003522 220.0
HKD2_k127_3017725_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000316 134.0
HKD2_k127_3017755_0 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000002807 218.0
HKD2_k127_3017755_1 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000004925 114.0
HKD2_k127_3017755_2 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000000002762 75.0
HKD2_k127_3017755_3 phosphatase - - - 0.00000000007299 71.0
HKD2_k127_304978_0 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 7.321e-238 749.0
HKD2_k127_304978_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 536.0
HKD2_k127_304978_10 granule-associated protein - - - 0.00000000000000001501 96.0
HKD2_k127_304978_11 Single-stranded DNA-binding protein K03111 - - 0.000000003145 63.0
HKD2_k127_304978_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 443.0
HKD2_k127_304978_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 412.0
HKD2_k127_304978_4 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 396.0
HKD2_k127_304978_5 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 339.0
HKD2_k127_304978_6 PFAM Pentapeptide repeats (8 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003849 247.0
HKD2_k127_304978_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000001544 205.0
HKD2_k127_304978_8 Sterol carrier protein - - - 0.0000000000000000000000000000005085 138.0
HKD2_k127_304978_9 - - - - 0.000000000000000000000007139 106.0
HKD2_k127_3055245_0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 366.0
HKD2_k127_3055245_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000004335 172.0
HKD2_k127_3055245_2 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000005142 130.0
HKD2_k127_3062643_0 Had-superfamily hydrolase, subfamily ia, variant 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000239 257.0
HKD2_k127_3062643_1 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000000000000001706 202.0
HKD2_k127_3062643_2 Belongs to the NUDIX hydrolase family - - - 0.000000000000000000000000000000000000000000000000971 186.0
HKD2_k127_3062643_3 UvrD/REP helicase N-terminal domain - - - 0.000000000000000000000000000000004846 131.0
HKD2_k127_3063888_0 Protein of unknown function (DUF3710) - - - 0.00000000000000000000000000000000000000000000000001248 196.0
HKD2_k127_3063888_1 chromosome partitioning - - - 0.00000000000000000001761 95.0
HKD2_k127_3063888_2 carboxylic ester hydrolase activity - - - 0.0001189 52.0
HKD2_k127_3128875_0 PFAM Anion-transporting ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 589.0
HKD2_k127_3128875_1 Anion-transporting ATPase - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 471.0
HKD2_k127_3128875_2 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0030312,GO:0043254,GO:0044087,GO:0044464,GO:0047134,GO:0048037,GO:0050789,GO:0050794,GO:0051128,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071944,GO:0090034,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000101 136.0
HKD2_k127_3128875_3 prohibitin homologues - - - 0.0000000000000000000003481 103.0
HKD2_k127_3130910_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1164.0
HKD2_k127_3130910_1 Galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 513.0
HKD2_k127_3130910_2 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 412.0
HKD2_k127_3130910_3 - - - - 0.000000000000000002329 89.0
HKD2_k127_3130910_4 Antitoxin Phd_YefM, type II toxin-antitoxin system K19159 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.0000000000000001375 89.0
HKD2_k127_3130910_5 toxin-antitoxin pair type II binding - - - 0.0000006359 56.0
HKD2_k127_3136984_0 PFAM Aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 596.0
HKD2_k127_3136984_1 Cell wall hydrolase autolysin K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 528.0
HKD2_k127_3136984_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 512.0
HKD2_k127_3136984_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 412.0
HKD2_k127_3136984_4 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 366.0
HKD2_k127_3136984_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000001832 235.0
HKD2_k127_3136984_6 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000005159 186.0
HKD2_k127_3136984_7 serine threonine protein kinase - - - 0.0000000000000000000000000000000001101 140.0
HKD2_k127_3136984_8 AntiSigma factor - - - 0.000000000000000000000008641 117.0
HKD2_k127_3144608_0 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 350.0
HKD2_k127_3144608_1 PFAM Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 303.0
HKD2_k127_3144608_2 PFAM Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001018 294.0
HKD2_k127_3144608_3 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000004636 131.0
HKD2_k127_3160015_0 TIGRFAM 2-oxoglutarate dehydrogenase, E1 K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.0 1464.0
HKD2_k127_3160015_1 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000206 293.0
HKD2_k127_3160015_2 PFAM Alcohol dehydrogenase, zinc-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009884 256.0
HKD2_k127_3160015_3 - - - - 0.00000000000000000000000421 102.0
HKD2_k127_3160015_4 ribonuclease activity - GO:0005575,GO:0005576,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - 0.0000000004963 67.0
HKD2_k127_3198238_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 1334.0
HKD2_k127_3198238_1 integral membrane protein - - - 0.0000000000000000000000000000000000000000000001466 171.0
HKD2_k127_3217246_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 494.0
HKD2_k127_3217246_1 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005156 254.0
HKD2_k127_3217246_10 - - - - 0.000000000000000000000000000000002095 136.0
HKD2_k127_3217246_11 Metal-sensitive transcriptional repressor - - - 0.000000000000000000000006392 104.0
HKD2_k127_3217246_12 Rhodanese domain protein - - - 0.000000000001118 78.0
HKD2_k127_3217246_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002286 246.0
HKD2_k127_3217246_3 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000003606 246.0
HKD2_k127_3217246_4 SNARE associated Golgi protein K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000002052 218.0
HKD2_k127_3217246_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000001313 200.0
HKD2_k127_3217246_6 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000002805 178.0
HKD2_k127_3217246_7 Belongs to the thioredoxin family K00384,K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000002678 171.0
HKD2_k127_3217246_8 Methyltransferase domain - - - 0.00000000000000000000000000000000001658 153.0
HKD2_k127_3217246_9 PFAM OsmC family protein - - - 0.00000000000000000000000000000000009573 136.0
HKD2_k127_3218269_0 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine K18912 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.14.99.50 1.753e-215 680.0
HKD2_k127_3218269_1 Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine K18911 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008213,GO:0008276,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0019439,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0036211,GO:0042398,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052707,GO:0052708,GO:0052709,GO:0052803,GO:0052805,GO:0071704,GO:0071944,GO:0097164,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 443.0
HKD2_k127_3218269_2 Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine K07008 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006518,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006749,GO:0006751,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0019439,GO:0019752,GO:0032991,GO:0034641,GO:0042219,GO:0042398,GO:0043171,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0051186,GO:0051187,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0061672,GO:0071704,GO:0071944,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1905368 3.5.1.118 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008812 283.0
HKD2_k127_3218269_3 phosphatase activity K07025 - - 0.00000000000000000000000000000000000000001739 158.0
HKD2_k127_3218269_4 Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine K01919 GO:0003674,GO:0003824,GO:0004357,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0044464,GO:0071944 6.3.2.2 0.000000000000000000000001384 105.0
HKD2_k127_3219793_0 PFAM sugar transferase - - - 1.441e-202 643.0
HKD2_k127_3219793_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 344.0
HKD2_k127_3219793_10 toxin-antitoxin pair type II binding - - - 0.00000000000002644 76.0
HKD2_k127_3219793_2 PFAM Inositol monophosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 321.0
HKD2_k127_3219793_3 Flavoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000001152 228.0
HKD2_k127_3219793_4 DNA primase, small subunit - - - 0.000000000000000000000000000000000000000000000000003569 187.0
HKD2_k127_3219793_5 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000004186 168.0
HKD2_k127_3219793_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000223 144.0
HKD2_k127_3219793_7 sequence-specific DNA binding - - - 0.00000000000000000000000000000003563 137.0
HKD2_k127_3219793_8 Transcriptional regulator - - - 0.00000000000000000000000000002755 129.0
HKD2_k127_3219793_9 DNA ligase (ATP) activity - - - 0.00000000000000000006585 96.0
HKD2_k127_3243208_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000001198 202.0
HKD2_k127_3243208_1 pfam nlp p60 - - - 0.00000000000000000000000000000000000000000000002349 176.0
HKD2_k127_3243208_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000005817 189.0
HKD2_k127_3243208_3 PucR C-terminal helix-turn-helix domain - - - 0.000000000000000000000000002797 127.0
HKD2_k127_3243208_4 PucR C-terminal helix-turn-helix domain - - - 0.000000000000000000000000114 119.0
HKD2_k127_3243208_5 - K18481 - - 0.00000003734 62.0
HKD2_k127_3313_0 protein phosphatase 2C domain protein K20074 GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 420.0
HKD2_k127_3313_1 FHA domain containing protein - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 313.0
HKD2_k127_3313_2 FHA domain containing protein - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000003783 220.0
HKD2_k127_3313_3 Putative esterase - - - 0.000000000000000000000000000000000000002273 151.0
HKD2_k127_3313_4 response to heat K06867,K07090 - - 0.00000000000000000002073 101.0
HKD2_k127_3313_5 - - - - 0.000000000003319 78.0
HKD2_k127_3313_6 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000001409 74.0
HKD2_k127_3317462_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1156.0
HKD2_k127_3317462_1 TIGRFAM Malto-oligosyltrehalose synthase K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 5.4.99.15 0.0 1144.0
HKD2_k127_3317462_2 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 308.0
HKD2_k127_3317462_3 Protein of unknown function (DUF3145) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001921 263.0
HKD2_k127_3317462_4 Domain of unknown function (DUF4193) - - - 0.0000000000000000000000000000000000000000000001133 174.0
HKD2_k127_3362144_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 1.169e-263 831.0
HKD2_k127_3362144_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 459.0
HKD2_k127_3362144_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 475.0
HKD2_k127_3362144_3 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 384.0
HKD2_k127_3362144_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 324.0
HKD2_k127_3362144_5 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002984 265.0
HKD2_k127_3362144_6 photoreceptor activity - - - 0.0000000000000000000000000000000000000000000000000000007845 210.0
HKD2_k127_3362144_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000002339 64.0
HKD2_k127_3401173_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 486.0
HKD2_k127_3401173_1 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 351.0
HKD2_k127_3401173_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.00001756 47.0
HKD2_k127_3401173_3 DDE superfamily endonuclease - - - 0.00002976 46.0
HKD2_k127_3405282_0 PFAM cell divisionFtsK SpoIIIE - - - 4.43e-295 929.0
HKD2_k127_3405282_1 PFAM Glycosyl transferase, family 20 K00697 - 2.4.1.15,2.4.1.347 4.669e-264 822.0
HKD2_k127_3405282_10 GDP-mannose 4,6 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005951 244.0
HKD2_k127_3405282_11 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001206 236.0
HKD2_k127_3405282_12 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000326 225.0
HKD2_k127_3405282_13 phosphatidylinositol transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000004787 218.0
HKD2_k127_3405282_14 PFAM Phosphoglycerate mutase K08296 - - 0.0000000000000000000000000000000000000000000000000000002 205.0
HKD2_k127_3405282_15 Nudix hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000003564 209.0
HKD2_k127_3405282_16 SMART Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000000000002692 190.0
HKD2_k127_3405282_17 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000001298 193.0
HKD2_k127_3405282_18 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000007798 177.0
HKD2_k127_3405282_19 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000002998 179.0
HKD2_k127_3405282_2 AAA ATPase domain - - - 4.564e-261 842.0
HKD2_k127_3405282_20 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000003049 172.0
HKD2_k127_3405282_21 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000001932 166.0
HKD2_k127_3405282_22 PFAM cysteine dioxygenase type I - - - 0.000000000000000000000000000000000000000001049 168.0
HKD2_k127_3405282_24 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000000004065 143.0
HKD2_k127_3405282_25 - - - - 0.0000000000000000000001323 100.0
HKD2_k127_3405282_28 Pirin C-terminal cupin domain K06911 - - 0.0000000000001837 75.0
HKD2_k127_3405282_29 Sterol carrier protein - - - 0.00000000005888 72.0
HKD2_k127_3405282_3 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 591.0
HKD2_k127_3405282_31 PFAM cell divisionFtsK SpoIIIE - - - 0.0000004605 59.0
HKD2_k127_3405282_4 Acetamidase formamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 490.0
HKD2_k127_3405282_5 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 490.0
HKD2_k127_3405282_6 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 398.0
HKD2_k127_3405282_7 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 350.0
HKD2_k127_3405282_8 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 346.0
HKD2_k127_3405282_9 transport, permease protein K01992,K18233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005827 278.0
HKD2_k127_3441288_0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 8.283e-246 769.0
HKD2_k127_3441288_1 lysine 2,3-aminomutase K01843 - 5.4.3.2 9.494e-234 731.0
HKD2_k127_3441288_2 Belongs to the ABC transporter superfamily K10112 GO:0006810,GO:0008150,GO:0008643,GO:0009405,GO:0015766,GO:0015771,GO:0015772,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0071702 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 572.0
HKD2_k127_3441288_3 PFAM extracellular solute-binding protein family 1 K02027 GO:0006810,GO:0008150,GO:0008643,GO:0009405,GO:0015766,GO:0015771,GO:0015772,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0071702 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 500.0
HKD2_k127_3441288_4 Dehydrogenase K18012 - 1.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 495.0
HKD2_k127_3441288_5 PFAM binding-protein-dependent transport systems inner membrane component K02025 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 462.0
HKD2_k127_3441288_6 PFAM binding-protein-dependent transport systems inner membrane component K02026,K10119 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 426.0
HKD2_k127_3441288_7 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 371.0
HKD2_k127_3441288_8 Thioesterase superfamily K18014 - 4.3.1.14 0.00000000000000000000000000000002873 141.0
HKD2_k127_3441288_9 Calcineurin-like phosphoesterase - - - 0.000000000000008892 77.0
HKD2_k127_3474193_0 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 437.0
HKD2_k127_3474193_1 Glycosyl transferase 4-like K19424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 410.0
HKD2_k127_3474193_2 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 335.0
HKD2_k127_3474193_3 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005062 291.0
HKD2_k127_3474193_4 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002444 243.0
HKD2_k127_3474193_5 ATP-grasp - - - 0.00000000000000000002215 106.0
HKD2_k127_3502655_0 Permease for cytosine/purines, uracil, thiamine, allantoin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 442.0
HKD2_k127_3502655_1 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000003485 116.0
HKD2_k127_3502655_2 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000004863 104.0
HKD2_k127_3502655_3 polyketide cyclase - - - 0.00000000000000000000002932 113.0
HKD2_k127_3502655_4 Endoribonuclease L-PSP - - - 0.00000000004596 69.0
HKD2_k127_351858_0 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 558.0
HKD2_k127_351858_1 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 533.0
HKD2_k127_351858_2 Domain of unknown function (DUF4350) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000008696 228.0
HKD2_k127_351858_3 Domain of unknown function (DUF4129) - - - 0.0000000000000000000000000000000000003812 147.0
HKD2_k127_3519819_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 464.0
HKD2_k127_3519819_1 PFAM CHAD domain containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 457.0
HKD2_k127_3519819_10 - - - - 0.00000000000000004049 83.0
HKD2_k127_3519819_2 Aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 436.0
HKD2_k127_3519819_3 PFAM binding-protein-dependent transport systems inner membrane component K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 439.0
HKD2_k127_3519819_4 probably responsible for the translocation of the substrate across the membrane K02037,K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 426.0
HKD2_k127_3519819_5 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 GO:0002682,GO:0002683,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0015698,GO:0016020,GO:0016036,GO:0030312,GO:0031347,GO:0031348,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035821,GO:0040007,GO:0042594,GO:0043207,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0044464,GO:0045088,GO:0045824,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071496,GO:0071944,GO:0075136,GO:0080134 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 425.0
HKD2_k127_3519819_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 416.0
HKD2_k127_3519819_7 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 348.0
HKD2_k127_3519819_8 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000556 180.0
HKD2_k127_3519819_9 PFAM thiamineS protein K03636 - - 0.0000000000000000000002625 99.0
HKD2_k127_3554483_0 required for the transposition of insertion element IS2404 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 332.0
HKD2_k127_3554483_1 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000002384 229.0
HKD2_k127_3554483_2 DDE superfamily endonuclease - - - 0.00000000000000000003129 92.0
HKD2_k127_3554483_3 DDE superfamily endonuclease - - - 0.00000000001573 67.0
HKD2_k127_3602787_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 516.0
HKD2_k127_3602787_1 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 379.0
HKD2_k127_3602787_2 Organic hydroperoxide resistance protein - - - 0.0000000000000000000000000000000000000000000001223 171.0
HKD2_k127_3647591_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 316.0
HKD2_k127_3647591_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002055 296.0
HKD2_k127_372524_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 539.0
HKD2_k127_372524_1 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 517.0
HKD2_k127_372524_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 290.0
HKD2_k127_372524_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000304 199.0
HKD2_k127_372524_4 - - - - 0.000000000000000000004157 95.0
HKD2_k127_372524_5 diacylglycerol kinase, catalytic K19302 - 3.6.1.27 0.0000000006496 64.0
HKD2_k127_3727770_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 - 0.0 1727.0
HKD2_k127_3727770_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1026.0
HKD2_k127_3727770_10 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 331.0
HKD2_k127_3727770_12 ribonuclease activity - GO:0005575,GO:0005576,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - 0.000000000000000000001626 99.0
HKD2_k127_3727770_2 Evidence 2b Function of strongly homologous gene K02035 - - 4.702e-246 773.0
HKD2_k127_3727770_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 558.0
HKD2_k127_3727770_4 May be required for sporulation K09762 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 541.0
HKD2_k127_3727770_5 Belongs to the phosphoglycerate kinase family K00927,K01803 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 528.0
HKD2_k127_3727770_6 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 481.0
HKD2_k127_3727770_7 Displays ATPase and GTPase activities K06958 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 479.0
HKD2_k127_3727770_8 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 425.0
HKD2_k127_3727770_9 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 405.0
HKD2_k127_3738301_0 Circadian clock protein KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 554.0
HKD2_k127_3738301_1 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 357.0
HKD2_k127_3738301_10 MerR family transcriptional regulator K22491 - - 0.000000001102 68.0
HKD2_k127_3738301_2 Formate nitrite - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 296.0
HKD2_k127_3738301_3 PELOTA RNA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003152 250.0
HKD2_k127_3738301_4 SMART protein phosphatase 2C domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000009111 235.0
HKD2_k127_3738301_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K01768,K07315,K11928 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009165,GO:0009166,GO:0009187,GO:0009190,GO:0009214,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0052621,GO:0055086,GO:0071111,GO:0071704,GO:0071944,GO:0090407,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.1.3.3,4.6.1.1 0.00000000000000000000000000001344 136.0
HKD2_k127_3738301_6 - - - - 0.000000000000000000000004448 118.0
HKD2_k127_3738301_7 phosphorelay signal transduction system - - - 0.000000000000000000000006155 111.0
HKD2_k127_3738301_8 phosphatase activity - - - 0.000000000000000212 93.0
HKD2_k127_3738301_9 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000004524 85.0
HKD2_k127_3776790_0 transcriptional activator domain - - - 2.636e-308 983.0
HKD2_k127_3776790_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 487.0
HKD2_k127_3776790_2 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 308.0
HKD2_k127_3776790_3 - - - - 0.00000000000000000000000000000000000000000000000001641 184.0
HKD2_k127_378206_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0 1055.0
HKD2_k127_378206_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 548.0
HKD2_k127_378206_10 Mycofactocin system - - - 0.00000000000000000000000000000002574 128.0
HKD2_k127_378206_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.00000000000000000002221 101.0
HKD2_k127_378206_12 Bacterial antitoxin of type II TA system, VapB - GO:0006417,GO:0008150,GO:0009605,GO:0009607,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0040008,GO:0043207,GO:0044403,GO:0044419,GO:0045727,GO:0045927,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:2000112 - 0.000000000001603 78.0
HKD2_k127_378206_13 TIGRFAM transcriptional regulator, AbrB family - - - 0.000001831 56.0
HKD2_k127_378206_14 PIN domain - - - 0.000004891 55.0
HKD2_k127_378206_2 Cysteine desulfurase K04487 GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 540.0
HKD2_k127_378206_3 electron transfer flavoprotein, alpha subunit K03522 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 460.0
HKD2_k127_378206_4 PFAM Methionine synthase, vitamin-B12 independent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 426.0
HKD2_k127_378206_5 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 405.0
HKD2_k127_378206_6 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 411.0
HKD2_k127_378206_7 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 370.0
HKD2_k127_378206_8 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 336.0
HKD2_k127_378206_9 PFAM Creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002239 281.0
HKD2_k127_3793947_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0 1151.0
HKD2_k127_3793947_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001174 273.0
HKD2_k127_3793947_2 - - - - 0.00000000000000000004643 99.0
HKD2_k127_3828704_0 Participates in both transcription termination and antitermination K02600 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 560.0
HKD2_k127_3828704_1 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000007188 173.0
HKD2_k127_3828704_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000002769 123.0
HKD2_k127_3828704_3 Protein of unknown function (DUF448) K07742 - - 0.0000000000000000000000000001683 124.0
HKD2_k127_3877750_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.829e-308 951.0
HKD2_k127_3877750_1 Glycogen debranching enzyme - - - 8.583e-306 966.0
HKD2_k127_3877750_2 Scramblase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 397.0
HKD2_k127_3877750_3 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 293.0
HKD2_k127_3877750_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000322 224.0
HKD2_k127_3877750_6 Multicopper oxidase - - - 0.00000000000000000107 96.0
HKD2_k127_3877750_7 - - - - 0.00000000005262 72.0
HKD2_k127_3877750_8 - - - - 0.000000004643 66.0
HKD2_k127_3878203_0 UvrD/REP helicase N-terminal domain - - - 0.0 1273.0
HKD2_k127_3878203_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 464.0
HKD2_k127_3878203_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000000000000000000000001678 130.0
HKD2_k127_3878203_3 - - - - 0.0000000000000004465 81.0
HKD2_k127_3878203_4 F420H(2)-dependent quinone reductase - - - 0.0000000000000008557 78.0
HKD2_k127_3878203_5 - - - - 0.000000000001847 69.0
HKD2_k127_3879518_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1033.0
HKD2_k127_3879518_1 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 556.0
HKD2_k127_3879518_2 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971 414.0
HKD2_k127_3879518_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075 GO:0008150,GO:0040007 2.4.2.8,6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 352.0
HKD2_k127_3879518_4 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 305.0
HKD2_k127_3879518_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075 GO:0008150,GO:0040007 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000002828 282.0
HKD2_k127_3907076_0 SMART Elongator protein 3 MiaB NifB K11779 - 2.5.1.77 0.0 1347.0
HKD2_k127_3907076_1 tigrfam lppg K11212 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 383.0
HKD2_k127_3907076_2 Zincin-like metallopeptidase - - - 0.00000000000000000000000000000000000000001251 155.0
HKD2_k127_3907076_3 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.00000000000000000000000000000000000005979 147.0
HKD2_k127_3927242_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 8.262e-204 641.0
HKD2_k127_3927242_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 541.0
HKD2_k127_3927242_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01657,K02500 GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 419.0
HKD2_k127_3927242_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814,K01817 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 383.0
HKD2_k127_3927242_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 334.0
HKD2_k127_3927242_5 Imidazoleglycerol-phosphate dehydratase K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 339.0
HKD2_k127_3927242_6 ABC transporter, transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 301.0
HKD2_k127_3927242_7 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000005844 228.0
HKD2_k127_3927242_8 - - - - 0.000008596 49.0
HKD2_k127_3949747_0 Bifunctional purine biosynthesis protein PurH K00602 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 3.293e-217 681.0
HKD2_k127_3949747_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 513.0
HKD2_k127_3949747_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0040007,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 431.0
HKD2_k127_3949747_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003401 278.0
HKD2_k127_3949747_4 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000374 269.0
HKD2_k127_3949747_5 Peptidase family M23 - - - 0.000000000000000000000000000006763 134.0
HKD2_k127_3949747_6 Protein of unknown function (DUF3017) - - - 0.00000000000000007851 91.0
HKD2_k127_3949747_7 Membrane proteins related to metalloendopeptidases - - - 0.000000000000006327 86.0
HKD2_k127_3949747_8 ACT domain K09707 - - 0.00000000000006905 77.0
HKD2_k127_3952815_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001113 284.0
HKD2_k127_3952815_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000005207 175.0
HKD2_k127_3952815_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.00000000000000000000000000000000000000000006691 165.0
HKD2_k127_3952815_3 heat shock protein binding K03686 - - 0.000000000000000000000000000009443 126.0
HKD2_k127_3952815_4 Antitoxin component of a type II toxin-antitoxin (TA) system. Upon K19687 GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.0000000000000000000000767 101.0
HKD2_k127_3956620_0 Purine nucleoside phosphorylase involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 384.0
HKD2_k127_3956620_1 SAF - - - 0.000000000000000000000000000006685 129.0
HKD2_k127_3956620_2 Putative regulatory protein - - - 0.0000000000000000000000000007006 115.0
HKD2_k127_3970823_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K05551 - 2.3.1.235,2.3.1.260 1.106e-225 706.0
HKD2_k127_3970823_1 Major facilitator superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.739e-221 700.0
HKD2_k127_3970823_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 319.0
HKD2_k127_3970823_11 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 319.0
HKD2_k127_3970823_12 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 305.0
HKD2_k127_3970823_13 pyridine nucleotide-disulfide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002768 277.0
HKD2_k127_3970823_14 pyridoxamine 5-phosphate K05558 - - 0.0000000000000000000000000000000000000000000000000001492 188.0
HKD2_k127_3970823_15 Antibiotic biosynthesis monooxygenase K14632 - - 0.00000000000000000000000000000000000001044 153.0
HKD2_k127_3970823_16 alcohol dehydrogenase - - - 0.000000000000000000000000000000001048 133.0
HKD2_k127_3970823_17 Phosphopantetheine attachment site K05553 - - 0.000000000000000000001705 104.0
HKD2_k127_3970823_18 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000002347 91.0
HKD2_k127_3970823_2 Major facilitator Superfamily K05557 - - 3.85e-201 639.0
HKD2_k127_3970823_3 Beta-ketoacyl synthase, C-terminal domain K05552 - 2.3.1.235,2.3.1.260 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 595.0
HKD2_k127_3970823_4 acyl-CoA dehydrogenase K14630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 519.0
HKD2_k127_3970823_5 NmrA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 473.0
HKD2_k127_3970823_6 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 439.0
HKD2_k127_3970823_7 Polyketide cyclase / dehydrase and lipid transport K05554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 392.0
HKD2_k127_3970823_8 alcohol dehydrogenase K14629 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 370.0
HKD2_k127_3970823_9 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 368.0
HKD2_k127_3987117_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 368.0
HKD2_k127_3987117_1 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 334.0
HKD2_k127_3987117_2 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000347 248.0
HKD2_k127_3987117_3 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000007946 173.0
HKD2_k127_3987117_4 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000004285 98.0
HKD2_k127_3987117_5 Mitochondrial biogenesis AIM24 - - - 0.00000000000000003376 81.0
HKD2_k127_3988296_0 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005071 273.0
HKD2_k127_3988296_2 Transcriptional regulator - - - 0.0000000000000000000000000003414 120.0
HKD2_k127_3988296_3 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000003651 123.0
HKD2_k127_4030752_0 Dyp-type peroxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 353.0
HKD2_k127_4030752_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009412 263.0
HKD2_k127_4030752_2 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000004983 227.0
HKD2_k127_4030752_3 ribonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000006954 212.0
HKD2_k127_4030752_4 - - - - 0.00000000000000000000000000000000000000000000007944 180.0
HKD2_k127_4030752_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000133 173.0
HKD2_k127_4030752_6 Transposase - - - 0.00000000000000000000000000000000000005743 144.0
HKD2_k127_4030752_7 iron assimilation - - - 0.0000000000000000000000000000001545 130.0
HKD2_k127_4030752_8 toxin-antitoxin pair type II binding - - - 0.00000000000000000000000001084 110.0
HKD2_k127_4030752_9 Transposase - - - 0.000000000000000009321 93.0
HKD2_k127_4079172_0 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 469.0
HKD2_k127_4079172_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 365.0
HKD2_k127_4079172_2 PFAM glycosyl transferase, family 51 - - - 0.00000008807 61.0
HKD2_k127_4091059_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00271 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.4.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 511.0
HKD2_k127_4091059_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 374.0
HKD2_k127_4091059_10 ftsk spoiiie K03466 - - 0.00000000008954 74.0
HKD2_k127_4091059_11 - - - - 0.00000006764 59.0
HKD2_k127_4091059_13 Antirestriction protein (ArdA) - - - 0.0002886 50.0
HKD2_k127_4091059_14 Belongs to the 'phage' integrase family - - - 0.0006343 43.0
HKD2_k127_4091059_2 Belongs to the N(4) N(6)-methyltransferase family K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 363.0
HKD2_k127_4091059_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000641 280.0
HKD2_k127_4091059_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000008208 201.0
HKD2_k127_4091059_5 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000000000062 195.0
HKD2_k127_4091059_6 TIGRFAM DNA binding domain - - - 0.0000000000000000000000000000001037 124.0
HKD2_k127_4091059_7 domain, Protein - - - 0.00000000000000000000000003452 121.0
HKD2_k127_4091059_8 Protein of unknown function (DUF3073) - - - 0.000000000000004102 78.0
HKD2_k127_4112247_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679 - 1.048e-257 805.0
HKD2_k127_4112247_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 4.161e-248 780.0
HKD2_k127_4112247_2 IMP dehydrogenase K00088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 525.0
HKD2_k127_4112247_3 Uroporphyrin-III C-methyltransferase K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 450.0
HKD2_k127_4112247_4 epimerase dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 310.0
HKD2_k127_4112247_5 transcriptional regulator K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 297.0
HKD2_k127_4112247_6 Family of unknown function (DUF5319) - - - 0.0000000000000000000000000000000000000000000000000000000000000004424 223.0
HKD2_k127_4112247_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000001868 178.0
HKD2_k127_4112247_8 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000000000002387 156.0
HKD2_k127_4197360_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.061e-293 944.0
HKD2_k127_4197360_1 Urocanase C-terminal domain K01712 - 4.2.1.49 1.222e-230 736.0
HKD2_k127_4197360_10 - - - - 0.000000001181 61.0
HKD2_k127_4197360_11 FtsK/SpoIIIE family K03466 - - 0.0007219 50.0
HKD2_k127_4197360_2 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 445.0
HKD2_k127_4197360_3 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 348.0
HKD2_k127_4197360_4 Belongs to the arginase family K01479,K01480 - 3.5.3.11,3.5.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 297.0
HKD2_k127_4197360_5 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000745 286.0
HKD2_k127_4197360_6 sporulation and cell division protein, SsgA - GO:0000003,GO:0000910,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006725,GO:0006732,GO:0007049,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009653,GO:0009987,GO:0010564,GO:0010927,GO:0016043,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0018958,GO:0019438,GO:0019748,GO:0019752,GO:0019954,GO:0022402,GO:0022607,GO:0030154,GO:0030312,GO:0030428,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0030638,GO:0030639,GO:0031160,GO:0032465,GO:0032467,GO:0032502,GO:0032506,GO:0032989,GO:0032991,GO:0040007,GO:0042180,GO:0042181,GO:0042221,GO:0042244,GO:0042546,GO:0043436,GO:0043648,GO:0043650,GO:0043934,GO:0043936,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044457,GO:0044464,GO:0044550,GO:0045229,GO:0045787,GO:0046189,GO:0046394,GO:0046483,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051188,GO:0051301,GO:0051302,GO:0051716,GO:0051726,GO:0051781,GO:0065007,GO:0070590,GO:0070726,GO:0070887,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0090068,GO:0090529,GO:1901110,GO:1901112,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1902074,GO:1902075,GO:1903664,GO:1903666,GO:1990586,GO:2000241,GO:2000243,GO:2000244,GO:2000246 - 0.000000000000000000000000000000000000000000000000000000009665 207.0
HKD2_k127_4197360_7 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000000000000000000001099 149.0
HKD2_k127_4197360_8 sequence-specific DNA binding - - - 0.00000000000000005743 96.0
HKD2_k127_4197360_9 - - - - 0.000000000000001686 85.0
HKD2_k127_4211243_0 PFAM Glycosyl transferase, group 1 - - - 7.38e-205 646.0
HKD2_k127_4211243_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 526.0
HKD2_k127_4211243_2 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 536.0
HKD2_k127_4211243_3 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 516.0
HKD2_k127_4211243_4 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 454.0
HKD2_k127_4211243_5 PFAM Glycosyl transferase family 2 K16870 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0045226,GO:0046379,GO:0071704,GO:0071944,GO:1901576 2.4.1.289 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 393.0
HKD2_k127_4211243_6 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 336.0
HKD2_k127_4220952_0 Belongs to the UbiD family K03182 - 4.1.1.98 1.89e-291 899.0
HKD2_k127_4220952_1 Cytochrome c-type biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 404.0
HKD2_k127_4220952_2 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 396.0
HKD2_k127_4220952_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 314.0
HKD2_k127_4220952_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000000000005001 182.0
HKD2_k127_4220952_5 Phospholipase_D-nuclease N-terminal - - - 0.000000000000001156 84.0
HKD2_k127_4220952_6 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944 - 0.00000000000001066 76.0
HKD2_k127_4230816_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000002719 171.0
HKD2_k127_4230816_1 - - - - 0.0000000000000000000000000006633 116.0
HKD2_k127_4230816_2 Transcriptional regulator - - - 0.00000000000000000000338 106.0
HKD2_k127_4230816_3 Acetyltransferase (GNAT) family - - - 0.000000000000000635 85.0
HKD2_k127_4293028_0 Methyltransferase domain protein K12710,K13317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000892 551.0
HKD2_k127_4293028_1 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 414.0
HKD2_k127_4293028_2 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 406.0
HKD2_k127_4293028_3 C-methyltransferase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 417.0
HKD2_k127_4293028_4 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000003113 254.0
HKD2_k127_4293028_5 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000007624 238.0
HKD2_k127_4293028_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000002024 197.0
HKD2_k127_4293028_7 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000000000000000009054 174.0
HKD2_k127_4293028_8 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000001063 164.0
HKD2_k127_4293028_9 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000271 74.0
HKD2_k127_4293492_0 Cation transporter/ATPase, N-terminus K01535,K01537,K12955 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.6,3.6.3.8 2.4e-250 825.0
HKD2_k127_4293492_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 339.0
HKD2_k127_4293492_10 - - - - 0.000000002217 63.0
HKD2_k127_4293492_11 Toxic component of a toxin-antitoxin (TA) module K07171 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005576,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0045927,GO:0046483,GO:0046700,GO:0048518,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000004561 58.0
HKD2_k127_4293492_13 Transcriptional regulator - - - 0.00000003896 63.0
HKD2_k127_4293492_2 TRANSCRIPTIONal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 292.0
HKD2_k127_4293492_3 TRANSCRIPTIONal - - - 0.00000000000000000000000000000000000000000000000000000000000000000004736 247.0
HKD2_k127_4293492_4 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000001202 225.0
HKD2_k127_4293492_5 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000000000000192 141.0
HKD2_k127_4293492_6 SNARE associated Golgi protein - - - 0.00000000000000000000000000000004561 133.0
HKD2_k127_4293492_7 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000002002 135.0
HKD2_k127_4293492_8 Toxic component of a toxin-antitoxin (TA) module K07171 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005576,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0045927,GO:0046483,GO:0046700,GO:0048518,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000005559 117.0
HKD2_k127_4293492_9 COG0474 Cation transport ATPase - - - 0.0000000000000009291 84.0
HKD2_k127_4339096_0 Domain of unknown function (DUF1929) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 460.0
HKD2_k127_4339096_1 Glycoside hydrolase 15-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 419.0
HKD2_k127_4339096_10 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000132 56.0
HKD2_k127_4339096_11 - - - - 0.0003034 46.0
HKD2_k127_4339096_2 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 374.0
HKD2_k127_4339096_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 366.0
HKD2_k127_4339096_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.00000000000000000000000000000002845 132.0
HKD2_k127_4339096_5 MarR family - - - 0.000000000000000000000000007875 123.0
HKD2_k127_4339096_6 self proteolysis - - - 0.00000000000000000000003323 115.0
HKD2_k127_4339096_7 PspC domain protein K03973 - - 0.0000000000000001013 83.0
HKD2_k127_4339096_8 Cupin domain - - - 0.000000000000000231 91.0
HKD2_k127_4339096_9 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000002719 67.0
HKD2_k127_4368572_0 Protein of unknown function (DUF3376) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 469.0
HKD2_k127_4368572_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 392.0
HKD2_k127_4368572_2 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 355.0
HKD2_k127_4368572_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000007117 119.0
HKD2_k127_4421775_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - 2.344e-292 920.0
HKD2_k127_4421775_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 449.0
HKD2_k127_4421775_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 GO:0000166,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0036094,GO:0040007,GO:0042083,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050797,GO:0070402,GO:0097159,GO:1901265,GO:1901363 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 416.0
HKD2_k127_4421775_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 378.0
HKD2_k127_4421775_4 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000000000000000000000000000008458 227.0
HKD2_k127_4421775_5 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000002329 198.0
HKD2_k127_4421775_6 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000006625 113.0
HKD2_k127_4421775_7 Domain of unknown function (DUF1918) - - - 0.0000000000000000000001589 99.0
HKD2_k127_4421775_8 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000174 64.0
HKD2_k127_4421775_9 integral membrane protein - - - 0.000001662 57.0
HKD2_k127_442995_0 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 412.0
HKD2_k127_442995_1 extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 363.0
HKD2_k127_442995_2 PFAM Alcohol dehydrogenase, zinc-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 353.0
HKD2_k127_442995_3 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.00000000000002309 81.0
HKD2_k127_4441086_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 412.0
HKD2_k127_4441086_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 357.0
HKD2_k127_4441086_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 315.0
HKD2_k127_4441086_3 alcohol dehydrogenase - - - 0.00000000000000000002204 107.0
HKD2_k127_4467080_0 Copper resistance protein CopC K14166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009441 455.0
HKD2_k127_4467080_1 peptidase S1 and S6, chymotrypsin Hap K08372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 404.0
HKD2_k127_4467080_2 Filamentation induced by cAMP protein fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 308.0
HKD2_k127_4467080_3 Transcription regulator of the Arc MetJ class - - - 0.000000000000000000000000000000000000000000000000002305 184.0
HKD2_k127_4467080_4 CoA-binding K06929 - - 0.000000000000000000000000000000000000000000000000006251 190.0
HKD2_k127_4467080_5 Secreted repeat of unknown function - - - 0.0000000000000000000002271 113.0
HKD2_k127_4467080_6 Fic/DOC family - - - 0.00000000000000006762 93.0
HKD2_k127_4467333_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1867.0
HKD2_k127_4467333_1 glutamate synthase - - - 1.803e-285 884.0
HKD2_k127_4467333_10 PIN domain K07062 - - 0.00000000000000000000000000000000000000000000000007842 180.0
HKD2_k127_4467333_11 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000005226 169.0
HKD2_k127_4467333_12 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000009441 152.0
HKD2_k127_4467333_13 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000008688 131.0
HKD2_k127_4467333_14 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000002005 131.0
HKD2_k127_4467333_15 Arc-like DNA binding domain K21495 - - 0.0000000000000000000003629 100.0
HKD2_k127_4467333_16 - - - - 0.0000000000000008157 85.0
HKD2_k127_4467333_17 PFAM AMP-dependent synthetase and ligase K12429,K18662 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.000002322 53.0
HKD2_k127_4467333_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 567.0
HKD2_k127_4467333_3 AMP-binding enzyme C-terminal domain K12429 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 522.0
HKD2_k127_4467333_4 Transport permease protein K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 446.0
HKD2_k127_4467333_5 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 447.0
HKD2_k127_4467333_6 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 430.0
HKD2_k127_4467333_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003084 289.0
HKD2_k127_4467333_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000002171 225.0
HKD2_k127_4467333_9 Domain of unkown function (DUF1775) K07040 - - 0.00000000000000000000000000000000000000000000000000000000002877 216.0
HKD2_k127_4483672_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 1.235e-251 794.0
HKD2_k127_4483672_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00322 - 1.6.1.1 8.891e-207 649.0
HKD2_k127_4483672_10 Protein of unknown function (DUF4245) - - - 0.0000000000000000000000000000000000000000000000008656 192.0
HKD2_k127_4483672_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000988,GO:0000990,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000001089 185.0
HKD2_k127_4483672_12 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000187 169.0
HKD2_k127_4483672_13 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00322 - 1.6.1.1 0.0000000000000000000000000000000000004406 142.0
HKD2_k127_4483672_14 Transglycosylase associated protein - - - 0.000000000000000000000000000000000006938 142.0
HKD2_k127_4483672_15 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000137 127.0
HKD2_k127_4483672_17 - - - - 0.000000000000000000000000007478 116.0
HKD2_k127_4483672_18 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000006691 110.0
HKD2_k127_4483672_19 Nucleotidyltransferase domain K07075 - - 0.00000000000000000000001147 102.0
HKD2_k127_4483672_2 CoA-transferase family III K07749,K18313 - 2.8.3.16,2.8.3.20 3.884e-201 636.0
HKD2_k127_4483672_20 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000000000000000000003181 99.0
HKD2_k127_4483672_21 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000005435 88.0
HKD2_k127_4483672_22 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000005891 92.0
HKD2_k127_4483672_23 AntiSigma factor K03088 - - 0.000000000000000001191 94.0
HKD2_k127_4483672_24 - - - - 0.000000000000000001628 93.0
HKD2_k127_4483672_25 Protein of unknown function (DUF1778) - - - 0.0000000000002097 75.0
HKD2_k127_4483672_26 - - - - 0.00000000002659 74.0
HKD2_k127_4483672_27 - - - - 0.0000000001461 66.0
HKD2_k127_4483672_28 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000002421 59.0
HKD2_k127_4483672_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 576.0
HKD2_k127_4483672_4 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 568.0
HKD2_k127_4483672_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 524.0
HKD2_k127_4483672_6 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 523.0
HKD2_k127_4483672_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 467.0
HKD2_k127_4483672_8 involved in chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000000000004556 206.0
HKD2_k127_4483672_9 Cell wall-active antibiotics response 4TMS YvqF - - - 0.000000000000000000000000000000000000000000000000000001905 210.0
HKD2_k127_4483726_0 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 516.0
HKD2_k127_4483726_1 Selenocysteine-specific translation elongation factor K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 514.0
HKD2_k127_4483726_2 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002459 248.0
HKD2_k127_4483726_4 - - - - 0.0000000000001162 72.0
HKD2_k127_4483866_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 1.111e-237 744.0
HKD2_k127_4483866_1 TIGRFAM Diguanylate cyclase - - - 6.129e-195 636.0
HKD2_k127_4483866_2 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 456.0
HKD2_k127_4483866_3 Sterol carrier protein - - - 0.00000000000000000000000000000000000000000000000000000000000009276 224.0
HKD2_k127_4483866_4 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000003186 138.0
HKD2_k127_4483866_5 Transmembrane secretion effector - - - 0.0000000000000000000000000000001099 131.0
HKD2_k127_4483866_6 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000001435 66.0
HKD2_k127_4525616_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1052.0
HKD2_k127_4525616_1 Belongs to the glutamate synthase family K00284 - 1.4.7.1 4.882e-249 776.0
HKD2_k127_4525616_10 hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001909 263.0
HKD2_k127_4525616_11 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000001284 174.0
HKD2_k127_4525616_12 - - - - 0.000000000000000000000000000000000000007839 147.0
HKD2_k127_4525616_13 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K21600 - - 0.0000000000000000000000000000000001251 136.0
HKD2_k127_4525616_14 sulfur carrier activity - - - 0.0000000000000000000000000000000007961 134.0
HKD2_k127_4525616_15 Peptidase family M23 - - - 0.000000000000000000000000000447 129.0
HKD2_k127_4525616_16 mercury ion transmembrane transporter activity - - - 0.0000000000000000003146 91.0
HKD2_k127_4525616_2 PFAM SMP-30 Gluconolaconase - - - 3.939e-200 665.0
HKD2_k127_4525616_3 Mur ligase middle domain - - - 1.058e-197 624.0
HKD2_k127_4525616_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 492.0
HKD2_k127_4525616_5 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 467.0
HKD2_k127_4525616_6 Aminotransferase class I and II K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 425.0
HKD2_k127_4525616_7 PFAM CobB CobQ domain protein glutamine amidotransferase K07009 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 397.0
HKD2_k127_4525616_8 signal transduction histidine kinase K07653 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 367.0
HKD2_k127_4525616_9 Transcriptional regulatory protein, C terminal K07669,K07672 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 317.0
HKD2_k127_4531783_0 Aconitate hydratase 1 K01681 - 4.2.1.3 0.0 1264.0
HKD2_k127_4531783_1 Tyrosine phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001389 297.0
HKD2_k127_4535363_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.025e-279 871.0
HKD2_k127_4535363_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 616.0
HKD2_k127_4535363_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 356.0
HKD2_k127_4535363_3 Shikimate dehydrogenase K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000004423 288.0
HKD2_k127_4535363_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000001747 194.0
HKD2_k127_4535363_5 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000008727 164.0
HKD2_k127_4535363_6 aspartic-type endopeptidase activity K02654 - 3.4.23.43 0.00000000000000000000000000000000000001013 162.0
HKD2_k127_4545539_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.0 1073.0
HKD2_k127_4613689_0 E1-E2 ATPase K12952 - - 2.564e-276 874.0
HKD2_k127_4613689_1 metallopeptidase activity K16922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 408.0
HKD2_k127_4613689_2 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 388.0
HKD2_k127_4613689_3 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000001441 134.0
HKD2_k127_4613689_4 Peptidase M50 K16922 - - 0.000000006392 69.0
HKD2_k127_4613689_5 Helix-turn-helix domain - - - 0.0002385 49.0
HKD2_k127_4622360_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 340.0
HKD2_k127_4622360_1 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 315.0
HKD2_k127_4622360_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001427 288.0
HKD2_k127_4622360_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008003 291.0
HKD2_k127_4622360_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007714 291.0
HKD2_k127_4622360_5 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000008035 199.0
HKD2_k127_4622360_6 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000005266 183.0
HKD2_k127_4622360_7 Tetratricopeptide repeat - - - 0.00000000000000001789 93.0
HKD2_k127_4622360_8 PIN domain - - - 0.0000000003141 66.0
HKD2_k127_4625275_0 ABC transporter, transmembrane region K06147 - - 2.55e-304 948.0
HKD2_k127_4625275_1 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 1.078e-199 630.0
HKD2_k127_4625275_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003373 260.0
HKD2_k127_4677635_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 607.0
HKD2_k127_4677635_1 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 560.0
HKD2_k127_4677635_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 528.0
HKD2_k127_4677635_3 Helicase conserved C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 400.0
HKD2_k127_4677635_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000007433 207.0
HKD2_k127_4694925_0 FAD binding domain - - - 1.053e-263 816.0
HKD2_k127_4694925_1 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 389.0
HKD2_k127_4694925_10 - - - - 0.00000000000001779 85.0
HKD2_k127_4694925_11 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000179 61.0
HKD2_k127_4694925_12 F subunit of K+-transporting ATPase (Potass_KdpF) - - - 0.00000008567 58.0
HKD2_k127_4694925_2 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 363.0
HKD2_k127_4694925_3 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 361.0
HKD2_k127_4694925_4 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 321.0
HKD2_k127_4694925_5 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000004854 184.0
HKD2_k127_4694925_6 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000005717 178.0
HKD2_k127_4694925_7 LysE type translocator - - - 0.0000000000000000000000000000000002059 139.0
HKD2_k127_4694925_8 Cold shock protein K03704 - - 0.0000000000000000000000000000007927 125.0
HKD2_k127_4694925_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000006702 97.0
HKD2_k127_4695621_0 PFAM ABC transporter K15738 - - 3.679e-231 754.0
HKD2_k127_4695621_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 385.0
HKD2_k127_4695621_2 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000000000000000000000000001053 185.0
HKD2_k127_4695621_3 - - - - 0.00000000000000364 82.0
HKD2_k127_4695621_4 Protein conserved in bacteria - - - 0.00000000002908 74.0
HKD2_k127_4725571_0 Transposase DDE domain group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 324.0
HKD2_k127_4725571_1 Transposase DDE domain group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000001444 224.0
HKD2_k127_476482_0 Aldehyde dehydrogenase family K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 0.0 1201.0
HKD2_k127_476482_1 Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000000000000000000000000007812 213.0
HKD2_k127_476482_2 - - - - 0.000000000000000000000000000000000000000002751 164.0
HKD2_k127_476482_4 Redoxin K03564 - 1.11.1.15 0.0000000000000000000002603 98.0
HKD2_k127_476482_5 membrane protein (DUF2078) - - - 0.000000000000000003471 87.0
HKD2_k127_476482_6 His Kinase A (phospho-acceptor) domain - - - 0.000000000000002171 89.0
HKD2_k127_4813418_0 Helix-hairpin-helix class 2 (Pol1 family) motifs - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 375.0
HKD2_k127_4813418_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 378.0
HKD2_k127_4813418_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 355.0
HKD2_k127_4813418_3 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001371 241.0
HKD2_k127_4813418_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000074 61.0
HKD2_k127_482425_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 609.0
HKD2_k127_482425_1 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009869 424.0
HKD2_k127_482425_11 - - - - 0.00000000000000000000000000000000000000002388 176.0
HKD2_k127_482425_12 Belongs to the short-chain dehydrogenases reductases (SDR) family K00218 - 1.3.1.33 0.000000000000000000000000000638 118.0
HKD2_k127_482425_14 Phage integrase family - - - 0.0000000000000000000025 100.0
HKD2_k127_482425_15 - - - - 0.00000000000000000003355 102.0
HKD2_k127_482425_17 PFAM plasmid stabilization system - - - 0.00000000000000000207 90.0
HKD2_k127_482425_18 FMN-dependent dehydrogenase - - - 0.00000000000000005664 88.0
HKD2_k127_482425_19 chitinase - - - 0.000000000000001063 85.0
HKD2_k127_482425_2 ABC-2 family transporter protein K01990,K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000345 243.0
HKD2_k127_482425_21 chitinase - - - 0.0007037 53.0
HKD2_k127_482425_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 - 3.5.4.1,3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000001864 223.0
HKD2_k127_482425_4 pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000003137 248.0
HKD2_k127_482425_5 Enoyl-(Acyl carrier protein) reductase K00218 - 1.3.1.33 0.00000000000000000000000000000000000000000000000000000000000006168 225.0
HKD2_k127_482425_6 isomerase activity - - - 0.00000000000000000000000000000000000000000000000000000001967 205.0
HKD2_k127_482425_7 - - - - 0.00000000000000000000000000000000000000000000000009811 199.0
HKD2_k127_482425_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000008851 162.0
HKD2_k127_483071_0 cellular response to dsDNA K11211,K19302 - 2.7.1.166,3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 556.0
HKD2_k127_483071_1 Lysylphosphatidylglycerol synthase TM region K19302 - 3.6.1.27 0.00000000000000000000000000000002767 145.0
HKD2_k127_486558_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 499.0
HKD2_k127_486558_1 PAS PAC sensor signal transduction histidine kinase K18350 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 492.0
HKD2_k127_486558_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 329.0
HKD2_k127_486558_3 phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000002232 263.0
HKD2_k127_4878819_0 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 463.0
HKD2_k127_4878819_1 Acetyltransferase (isoleucine patch K00661 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.3.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 359.0
HKD2_k127_4878819_2 enoyl-CoA hydratase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 353.0
HKD2_k127_4878819_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000002574 174.0
HKD2_k127_4894138_0 Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 450.0
HKD2_k127_4894138_1 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 319.0
HKD2_k127_4894138_2 AAA domain - - - 0.00000000000000000000000000003373 128.0
HKD2_k127_4894138_3 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000563 112.0
HKD2_k127_4894138_4 AAA domain - - - 0.000001085 59.0
HKD2_k127_4915569_0 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 474.0
HKD2_k127_4915569_1 Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.1.1.16,6.3.1.13 0.0000000000000000000000000000000002139 134.0
HKD2_k127_4915569_2 Vitamin B12 dependent methionine synthase activation K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.000000000000000001252 100.0
HKD2_k127_4915569_3 regulation of cell shape K07484,K17763,K21471 - - 0.000000000000000005446 96.0
HKD2_k127_4915569_4 regulation of cell shape K07484,K17763,K21471 - - 0.000000006646 60.0
HKD2_k127_499498_0 GMC oxidoreductase K03333 - 1.1.3.6 2.252e-246 772.0
HKD2_k127_499498_1 Transcriptional regulator, CarD family K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 306.0
HKD2_k127_499498_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000001141 248.0
HKD2_k127_499498_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000001006 228.0
HKD2_k127_499498_4 - - - - 0.000000000000000000000000000000000000000000005594 174.0
HKD2_k127_499498_5 synthase K16167 - - 0.00000000000000004371 81.0
HKD2_k127_5007214_0 Glucodextranase, domain N K01178 - 3.2.1.3 3.358e-282 910.0
HKD2_k127_5007214_1 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002226 291.0
HKD2_k127_5007214_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.00000000000000000000000000000000000000000000000000000000000000001945 245.0
HKD2_k127_5007214_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.000000009758 59.0
HKD2_k127_5060_0 CoA-binding domain protein - - - 6.117e-292 923.0
HKD2_k127_5060_1 Alcohol dehydrogenase GroES-like domain K18369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 549.0
HKD2_k127_5060_2 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 521.0
HKD2_k127_5060_3 PFAM GPR1 FUN34 yaaH family K07034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001067 260.0
HKD2_k127_5060_4 CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000212 241.0
HKD2_k127_5060_5 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000352 217.0
HKD2_k127_5060_6 Universal stress protein - - - 0.0000000000000000007444 93.0
HKD2_k127_5060_7 Domain of unknown function (DUF1876) - - - 0.000000000000004601 81.0
HKD2_k127_5060_8 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000009948 65.0
HKD2_k127_5111323_0 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 1.7e-219 698.0
HKD2_k127_5111323_1 Predicted membrane protein (DUF2142) K17414 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 525.0
HKD2_k127_5111323_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 359.0
HKD2_k127_5111323_3 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 322.0
HKD2_k127_5111323_4 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000003858 181.0
HKD2_k127_5111323_5 Small Multidrug Resistance protein - - - 0.0000000000000000000000000000000000000000003529 165.0
HKD2_k127_5111323_6 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.000003223 60.0
HKD2_k127_5111323_7 - - - - 0.000003242 53.0
HKD2_k127_511848_0 PFAM ATPase associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 464.0
HKD2_k127_511848_1 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 374.0
HKD2_k127_511848_2 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 329.0
HKD2_k127_511848_3 Phosphoglucomutase K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000002092 160.0
HKD2_k127_511848_4 L-lactate permease K03303 - - 0.00000000000000000000000000000000000001009 146.0
HKD2_k127_5121039_0 acetyltransferase - GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007981 263.0
HKD2_k127_5121039_1 HAD-superfamily hydrolase, subfamily IIB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001477 249.0
HKD2_k127_5121039_2 mRNA binding K07339 - - 0.000000000000004681 85.0
HKD2_k127_5121039_3 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000001424 76.0
HKD2_k127_5140726_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 599.0
HKD2_k127_5140726_1 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 342.0
HKD2_k127_5140726_2 aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000385 231.0
HKD2_k127_5140726_3 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000003598 216.0
HKD2_k127_5140726_4 NUDIX domain - - - 0.0000000000000000000000000000003631 134.0
HKD2_k127_5140726_6 Helix-turn-helix - - - 0.0000000000000000000001634 103.0
HKD2_k127_5140726_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000000001579 82.0
HKD2_k127_5140741_0 ATP- GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004488 282.0
HKD2_k127_5140741_1 Roadblock lc7 family protein K07131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006121 247.0
HKD2_k127_5140741_3 Protein of unknown function (DUF742) - - - 0.000000000000000000008616 96.0
HKD2_k127_5140741_4 ATP- GTP-binding protein K06945 - - 0.000000009733 64.0
HKD2_k127_5140741_5 protein kinase activity - - - 0.00000536 57.0
HKD2_k127_5150952_0 PFAM Histone deacetylase K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 503.0
HKD2_k127_5150952_1 PFAM NAD-dependent epimerase dehydratase K01784 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 490.0
HKD2_k127_5150952_10 PFAM Ppx GppA phosphatase K01524 GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004182 270.0
HKD2_k127_5150952_2 PFAM Phospholipid glycerol acyltransferase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 481.0
HKD2_k127_5150952_3 PFAM Xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 466.0
HKD2_k127_5150952_4 ABC transporter K01990,K13926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 444.0
HKD2_k127_5150952_5 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 392.0
HKD2_k127_5150952_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 392.0
HKD2_k127_5150952_7 Pyrroline-5-carboxylate reductase dimerisation K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 393.0
HKD2_k127_5150952_8 transferase activity, transferring alkyl or aryl (other than methyl) groups K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 372.0
HKD2_k127_5150952_9 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 340.0
HKD2_k127_5151894_0 MBOAT, membrane-bound O-acyltransferase family K03739,K19294 - - 9.239e-210 691.0
HKD2_k127_5151894_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 602.0
HKD2_k127_5151894_2 Transposase DDE domain K07492 - - 0.000000000000000000000000000000000000000000000000000000000000007789 224.0
HKD2_k127_5153512_0 SMART Nucleotide binding protein, PINc K07175 - - 1.405e-236 739.0
HKD2_k127_5153512_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 355.0
HKD2_k127_5153512_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 316.0
HKD2_k127_5153512_3 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000000000000000009094 190.0
HKD2_k127_5153512_4 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000004952 170.0
HKD2_k127_5153512_5 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000002761 148.0
HKD2_k127_5153512_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000001026 57.0
HKD2_k127_5156228_0 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004388 279.0
HKD2_k127_5156228_2 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity - - - 0.0000000000000000000000000002644 121.0
HKD2_k127_5156228_3 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000004324 106.0
HKD2_k127_5156228_4 regulatory protein - - - 0.00000000000000005537 81.0
HKD2_k127_5156228_5 Hypothetical methyltransferase - - - 0.00000000000004253 82.0
HKD2_k127_5156228_6 Radical SAM - - - 0.00000000005415 77.0
HKD2_k127_5156228_7 Methyltransferase type 12 - - - 0.0000000338 66.0
HKD2_k127_5156228_8 radical SAM domain protein K07011,K22227 - - 0.000000245 63.0
HKD2_k127_5159478_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 567.0
HKD2_k127_5159478_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 554.0
HKD2_k127_5159478_10 Helix-turn-helix domain - - - 0.00000000001373 76.0
HKD2_k127_5159478_11 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000001178 65.0
HKD2_k127_5159478_12 PFAM Transposase DDE domain - - - 0.0000001214 55.0
HKD2_k127_5159478_2 PFAM Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 400.0
HKD2_k127_5159478_3 PFAM Peptidase M22, glycoprotease K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000532 211.0
HKD2_k127_5159478_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06925 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000015 205.0
HKD2_k127_5159478_5 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000005982 201.0
HKD2_k127_5159478_6 phosphonoacetaldehyde hydrolase activity K19270 - 3.1.3.23 0.0000000000000000000000000000000000000000000004575 188.0
HKD2_k127_5159478_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000003503 159.0
HKD2_k127_5159478_8 Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000000000865 119.0
HKD2_k127_515969_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1379.0
HKD2_k127_515969_1 DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 324.0
HKD2_k127_515969_2 PFAM pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 309.0
HKD2_k127_515969_3 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008578 268.0
HKD2_k127_515969_4 Regulator K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007825 250.0
HKD2_k127_515969_5 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000001489 243.0
HKD2_k127_515969_6 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000000000000001398 186.0
HKD2_k127_515969_7 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000102 152.0
HKD2_k127_5164596_0 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000000000000008618 187.0
HKD2_k127_5164596_1 Bacterial TniB protein K03696,K03697 - - 0.000000000000000000000000000000000000000000004611 179.0
HKD2_k127_5164596_2 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000005533 168.0
HKD2_k127_5164596_3 Formate nitrite - - - 0.0000000000000001071 81.0
HKD2_k127_5164596_4 UDP binding domain K02472,K13015 - 1.1.1.136,1.1.1.336 0.00000000005155 66.0
HKD2_k127_5165549_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 1.432e-199 628.0
HKD2_k127_5165549_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 298.0
HKD2_k127_5165549_2 - - - - 0.0000000003441 64.0
HKD2_k127_5165549_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000002605 70.0
HKD2_k127_5167491_0 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 419.0
HKD2_k127_5167491_1 PFAM sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003052 248.0
HKD2_k127_5167491_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000002241 202.0
HKD2_k127_5167491_4 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000003176 141.0
HKD2_k127_5167491_5 - - - - 0.000000000000000000000000002914 115.0
HKD2_k127_5167491_6 PIN domain - - - 0.00000000000000000000000001628 121.0
HKD2_k127_5167491_7 Histidine kinase-like ATPases - - - 0.000000000000000000001643 109.0
HKD2_k127_5167491_8 2'-5' RNA ligase superfamily - - - 0.00002242 48.0
HKD2_k127_5171790_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K20928 - 1.2.1.3,1.2.1.8,1.2.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 513.0
HKD2_k127_5171790_1 Rieske 2Fe-2S K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 341.0
HKD2_k127_5171790_2 Aldolase K08321,K11645,K18287 - 2.3.1.245,4.1.2.13,4.1.2.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 310.0
HKD2_k127_5171790_3 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000154 170.0
HKD2_k127_5171790_4 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000001213 132.0
HKD2_k127_5177144_0 Belongs to the class-II DAHP synthase family K01626,K16019 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0022607,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.5.1.54 7.623e-239 743.0
HKD2_k127_5177144_1 Phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 4.532e-237 741.0
HKD2_k127_5177144_10 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 440.0
HKD2_k127_5177144_11 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 425.0
HKD2_k127_5177144_12 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 394.0
HKD2_k127_5177144_13 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 398.0
HKD2_k127_5177144_14 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 362.0
HKD2_k127_5177144_15 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 334.0
HKD2_k127_5177144_16 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 293.0
HKD2_k127_5177144_17 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000398 284.0
HKD2_k127_5177144_18 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000007036 252.0
HKD2_k127_5177144_19 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001066 230.0
HKD2_k127_5177144_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009278 588.0
HKD2_k127_5177144_20 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000009154 192.0
HKD2_k127_5177144_21 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000005306 188.0
HKD2_k127_5177144_22 transcriptional regulator - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010565,GO:0016310,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000004024 179.0
HKD2_k127_5177144_23 - - - - 0.000000000000000000000000000000000000000000000009302 183.0
HKD2_k127_5177144_24 lycopene cyclase - - - 0.0000000000000000000000000000000000000000000002494 177.0
HKD2_k127_5177144_25 DNA mediated transformation - - - 0.000000000000000000000000000000000000000007237 161.0
HKD2_k127_5177144_26 phosphohydrolase - - - 0.00000000000000000000000000000000000836 139.0
HKD2_k127_5177144_27 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000002336 134.0
HKD2_k127_5177144_28 lycopene cyclase domain - - - 0.00000000000000000000000000000003834 138.0
HKD2_k127_5177144_29 Transposase DDE domain - - - 0.000000000000000000000002437 108.0
HKD2_k127_5177144_3 Biotin and Thiamin Synthesis associated K03150 - 4.1.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 565.0
HKD2_k127_5177144_30 positive regulation of growth - - - 0.00000000000000000008823 97.0
HKD2_k127_5177144_31 PIN domain K07064 - - 0.0000000000000000002623 96.0
HKD2_k127_5177144_33 PFAM Integrase catalytic K07497 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000004248 88.0
HKD2_k127_5177144_34 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000001314 90.0
HKD2_k127_5177144_35 phosphohydrolase - - - 0.000000000001551 72.0
HKD2_k127_5177144_36 nucleotide phosphatase activity, acting on free nucleotides K06928 - 3.6.1.15 0.000001723 55.0
HKD2_k127_5177144_37 Transposase DDE domain - - - 0.00000462 48.0
HKD2_k127_5177144_4 PFAM ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 519.0
HKD2_k127_5177144_5 pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 483.0
HKD2_k127_5177144_6 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 458.0
HKD2_k127_5177144_7 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 474.0
HKD2_k127_5177144_8 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 453.0
HKD2_k127_5177144_9 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 427.0
HKD2_k127_5186551_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 9.817e-237 737.0
HKD2_k127_5186551_1 Aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 470.0
HKD2_k127_5186551_2 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005198 257.0
HKD2_k127_5186551_3 Belongs to the GARS family K01945,K11788 GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000005664 209.0
HKD2_k127_5186551_4 Transglycosylase-like domain K21687 - - 0.000000000000000000000000000000000000000000000000000008605 200.0
HKD2_k127_5186551_7 toxin-antitoxin pair type II binding - - - 0.000000000000000000001663 96.0
HKD2_k127_5188892_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 2.243e-320 1009.0
HKD2_k127_5188892_1 TIGRFAM glutamine synthetase, type I K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 1.047e-271 841.0
HKD2_k127_5188892_10 RDD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000143 214.0
HKD2_k127_5188892_11 TIGRFAM 2-oxoglutarate dehydrogenase, E2 component K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000003577 194.0
HKD2_k127_5188892_12 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000003007 111.0
HKD2_k127_5188892_13 PFAM Glutamine synthetase, catalytic K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.00000000000000001052 82.0
HKD2_k127_5188892_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 525.0
HKD2_k127_5188892_3 Belongs to the peptidase S51 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 393.0
HKD2_k127_5188892_4 epimerase dehydratase K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 377.0
HKD2_k127_5188892_5 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 361.0
HKD2_k127_5188892_6 Domain of unknown function (DUF4191) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 318.0
HKD2_k127_5188892_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 309.0
HKD2_k127_5188892_8 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004259 287.0
HKD2_k127_5188892_9 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000005664 244.0
HKD2_k127_5193623_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 304.0
HKD2_k127_5193623_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000314 284.0
HKD2_k127_5193623_2 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000143 209.0
HKD2_k127_5193623_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000009405 183.0
HKD2_k127_5193623_4 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000008783 130.0
HKD2_k127_5284728_0 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 1.922e-216 709.0
HKD2_k127_5284728_1 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 360.0
HKD2_k127_5284728_2 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000001608 211.0
HKD2_k127_5284728_3 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000002106 213.0
HKD2_k127_5284728_4 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000001566 144.0
HKD2_k127_5284728_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000002275 121.0
HKD2_k127_5284728_6 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 0.000000000000000000000000342 108.0
HKD2_k127_5284728_7 Peptidase dimerisation domain - - - 0.000000000000000000004757 95.0
HKD2_k127_5284728_8 Peptidase dimerisation domain - - - 0.000000000007432 78.0
HKD2_k127_5288396_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 572.0
HKD2_k127_5288396_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 531.0
HKD2_k127_5288396_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 474.0
HKD2_k127_5288396_3 Belongs to the peptidase M48B family K03799 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 471.0
HKD2_k127_5288396_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 444.0
HKD2_k127_5288396_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000027 263.0
HKD2_k127_5288396_6 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003453 287.0
HKD2_k127_5288396_7 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000003626 232.0
HKD2_k127_5288396_8 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339,K05578 - 1.6.5.3 0.000000000000000000000000000000000000000000000002311 182.0
HKD2_k127_5288396_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000004065 143.0
HKD2_k127_5308029_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.0 1046.0
HKD2_k127_5308029_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 1.407e-256 799.0
HKD2_k127_5308029_10 Serine threonine protein kinase - - - 0.00000000000000000000000000000000001574 147.0
HKD2_k127_5308029_11 sequence-specific DNA binding - - - 0.00000000000007345 72.0
HKD2_k127_5308029_12 - - - - 0.00000000002669 78.0
HKD2_k127_5308029_2 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 4.2.1.9 1.446e-255 814.0
HKD2_k127_5308029_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 2.236e-237 747.0
HKD2_k127_5308029_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 573.0
HKD2_k127_5308029_5 PFAM penicillin-binding protein transpeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 549.0
HKD2_k127_5308029_6 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 529.0
HKD2_k127_5308029_7 Peptidase family S51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 339.0
HKD2_k127_5308029_8 Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001126 285.0
HKD2_k127_5308029_9 serine threonine protein kinase - - - 0.0000000000000000000000000000000000001364 150.0
HKD2_k127_5343678_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 609.0
HKD2_k127_5343678_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 568.0
HKD2_k127_5343678_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 495.0
HKD2_k127_5343678_3 PFAM DivIVA family protein - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 308.0
HKD2_k127_5343678_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008444 265.0
HKD2_k127_5343678_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000722 253.0
HKD2_k127_5343678_6 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000001269 233.0
HKD2_k127_5343678_7 integral membrane protein K02221 - - 0.000000000000000000000000000002699 122.0
HKD2_k127_5394930_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000002683 193.0
HKD2_k127_5394930_1 - - - - 0.0000000000000000000000000000000000127 148.0
HKD2_k127_5495750_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1244.0
HKD2_k127_5495750_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 0.0 1189.0
HKD2_k127_5495750_10 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 311.0
HKD2_k127_5495750_11 TRANSCRIPTIONal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001942 287.0
HKD2_k127_5495750_12 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000241 254.0
HKD2_k127_5495750_13 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000002744 243.0
HKD2_k127_5495750_14 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000004638 246.0
HKD2_k127_5495750_15 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000003421 221.0
HKD2_k127_5495750_16 PFAM type III restriction protein res subunit - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000001375 204.0
HKD2_k127_5495750_17 TRANSCRIPTIONal - - - 0.0000000000000000000000000000000000000000000000000000002339 198.0
HKD2_k127_5495750_18 drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000009025 171.0
HKD2_k127_5495750_19 Divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000004442 128.0
HKD2_k127_5495750_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 8.45e-208 661.0
HKD2_k127_5495750_20 - - - - 0.000000000000000000000000001703 118.0
HKD2_k127_5495750_21 Response regulator receiver K02479 - - 0.00000000000000000000000002608 119.0
HKD2_k127_5495750_22 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000002892 107.0
HKD2_k127_5495750_23 Preprotein translocase subunit K03210 - - 0.000000000004316 78.0
HKD2_k127_5495750_24 helix_turn_helix, Lux Regulon - - - 0.000004095 60.0
HKD2_k127_5495750_3 PFAM type III restriction protein res subunit - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 3.042e-203 639.0
HKD2_k127_5495750_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 562.0
HKD2_k127_5495750_5 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 488.0
HKD2_k127_5495750_6 drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 460.0
HKD2_k127_5495750_7 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 457.0
HKD2_k127_5495750_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 435.0
HKD2_k127_5495750_9 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 424.0
HKD2_k127_5556283_0 nitric oxide reductase K04561 - 1.7.2.5 0.0 1189.0
HKD2_k127_5556283_1 Lycopene cyclase protein K06443 - 5.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 333.0
HKD2_k127_5556283_2 PFAM NAD-dependent epimerase dehydratase K21793,K22320 - 1.1.1.412 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 321.0
HKD2_k127_5556283_3 PFAM SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 299.0
HKD2_k127_5556283_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000005373 232.0
HKD2_k127_5556283_5 PFAM SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000001078 231.0
HKD2_k127_5556283_6 - - - - 0.00000000000000000000000000000000000000000000001502 197.0
HKD2_k127_5556283_7 Transposase DDE domain group 1 - - - 0.0000000000000000000000000000000000001364 149.0
HKD2_k127_5556283_8 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K06718 - 2.3.1.178 0.0000000000000000000000000000000001546 138.0
HKD2_k127_5572208_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 488.0
HKD2_k127_5572208_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 296.0
HKD2_k127_5572208_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000002482 216.0
HKD2_k127_5572208_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000001248 214.0
HKD2_k127_5572208_4 PIN domain - - - 0.0000000000000000000000000000002634 127.0
HKD2_k127_5585970_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.519e-275 862.0
HKD2_k127_5585970_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K04708 - 1.1.1.102 0.000000000000000000000000000000000000000000000000000000000000000000001358 247.0
HKD2_k127_5585970_2 Protein of unknown function (DUF3099) - - - 0.0000000000000000000000002169 108.0
HKD2_k127_5647383_0 domain, Protein - - - 2.709e-221 698.0
HKD2_k127_5647383_1 CBS domain - - - 1.786e-204 643.0
HKD2_k127_5647383_10 - - - - 0.000000000000000000000000000000000000000000000006438 180.0
HKD2_k127_5647383_11 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000009072 166.0
HKD2_k127_5647383_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0008150,GO:0040007 - 0.000000000000000000000000000000111 138.0
HKD2_k127_5647383_14 - - - - 0.00000000000000000000000003902 110.0
HKD2_k127_5647383_15 Protein of unknown function (DUF3117) - - - 0.00000000000000000000002754 103.0
HKD2_k127_5647383_16 Putative zinc-finger - - - 0.00000000000001524 86.0
HKD2_k127_5647383_17 Thioesterase superfamily protein - - - 0.0000005349 58.0
HKD2_k127_5647383_18 PIN domain - - - 0.000001263 61.0
HKD2_k127_5647383_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 528.0
HKD2_k127_5647383_3 Peptidase s1 and s6 chymotrypsin hap K08372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 394.0
HKD2_k127_5647383_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 346.0
HKD2_k127_5647383_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 335.0
HKD2_k127_5647383_6 PFAM O-methyltransferase, family 3 - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 299.0
HKD2_k127_5647383_7 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000003181 217.0
HKD2_k127_5647383_8 PFAM regulatory protein, MarR - - - 0.000000000000000000000000000000000000000000000000000000008675 207.0
HKD2_k127_5647383_9 antisigma factor binding K03598 - - 0.0000000000000000000000000000000000000000000000005802 189.0
HKD2_k127_5651054_0 TIGRFAM malto-oligosyltrehalose trehalohydrolase K01236 - 3.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 447.0
HKD2_k127_5651054_3 Helix-turn-helix - - - 0.0000228 50.0
HKD2_k127_567279_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 6.852e-218 698.0
HKD2_k127_567279_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.61e-203 643.0
HKD2_k127_567279_10 - - - - 0.00000000000000000000000001975 128.0
HKD2_k127_567279_11 ATP synthase subunit C K02124 - - 0.000000000000000000000004499 104.0
HKD2_k127_567279_12 pfam gyd - - - 0.000000000000000000000006339 106.0
HKD2_k127_567279_13 ATP synthase subunit D K02120 - - 0.00000000000000000005217 106.0
HKD2_k127_567279_14 manually curated - - - 0.000000000000000005881 83.0
HKD2_k127_567279_16 Bacterial regulatory proteins, tetR family - - - 0.0000000000008206 70.0
HKD2_k127_567279_17 Produces ATP from ADP in the presence of a proton gradient across the membrane - - - 0.00000000001008 75.0
HKD2_k127_567279_18 Produces ATP from ADP in the presence of a proton gradient across the membrane - - - 0.0000000001189 66.0
HKD2_k127_567279_2 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 542.0
HKD2_k127_567279_20 F420H(2)-dependent quinone reductase - - - 0.00008395 53.0
HKD2_k127_567279_21 Fungal family of unknown function (DUF1776) - - - 0.0001992 50.0
HKD2_k127_567279_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 341.0
HKD2_k127_567279_4 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003457 261.0
HKD2_k127_567279_5 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000000000000000000000000006125 222.0
HKD2_k127_567279_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000004181 212.0
HKD2_k127_567279_8 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000003858 156.0
HKD2_k127_567279_9 MMPL family K06994 - - 0.000000000000000000000000000000000005529 139.0
HKD2_k127_567641_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1804.0
HKD2_k127_567641_1 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 592.0
HKD2_k127_567641_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000002209 60.0
HKD2_k127_5680766_0 Sodium:sulfate symporter transmembrane region K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 399.0
HKD2_k127_5680766_1 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001133 272.0
HKD2_k127_5680766_2 Belongs to the long-chain O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000001451 182.0
HKD2_k127_5680766_3 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000000000000000000000006916 108.0
HKD2_k127_5681418_0 ABC transporter (Permease) K02004 - - 4.61e-215 705.0
HKD2_k127_5681418_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 293.0
HKD2_k127_5681418_10 Rv0623-like transcription factor K19687 GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.00000000000000000000000009225 109.0
HKD2_k127_5681418_11 required for the transposition of insertion element IS2404 - - - 0.000005682 48.0
HKD2_k127_5681418_2 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 285.0
HKD2_k127_5681418_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003397 253.0
HKD2_k127_5681418_4 Protein of unknown function (DUF4012) - - - 0.00000000000000000000000000000000000000000000000000000000001031 220.0
HKD2_k127_5681418_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000002562 204.0
HKD2_k127_5681418_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.000000000000000000000000000000000000000000000001474 177.0
HKD2_k127_5681418_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000002223 170.0
HKD2_k127_5681418_8 - - - - 0.0000000000000000000000000000000000006503 155.0
HKD2_k127_5681418_9 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress - - - 0.000000000000000000000000000000000001332 157.0
HKD2_k127_5718616_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1367.0
HKD2_k127_5718616_1 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 573.0
HKD2_k127_5718616_10 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000004385 130.0
HKD2_k127_5718616_11 - - - - 0.000000000000000000000000002953 123.0
HKD2_k127_5718616_12 Domain of unknown function (DUF1876) - - - 0.000000004477 68.0
HKD2_k127_5718616_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 492.0
HKD2_k127_5718616_3 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 435.0
HKD2_k127_5718616_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 374.0
HKD2_k127_5718616_5 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971 357.0
HKD2_k127_5718616_6 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 302.0
HKD2_k127_5718616_7 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001183 274.0
HKD2_k127_5718616_8 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002246 285.0
HKD2_k127_5718616_9 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000000224 188.0
HKD2_k127_5723084_0 Na H antiporter K05565,K14086 - - 2.002e-257 822.0
HKD2_k127_5723084_1 Glucoamylase and related glycosyl hydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 617.0
HKD2_k127_5723084_10 STAS domain - - - 0.00002039 56.0
HKD2_k127_5723084_2 TrkA-C domain K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 383.0
HKD2_k127_5723084_3 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 343.0
HKD2_k127_5723084_4 PucR C-terminal helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 314.0
HKD2_k127_5723084_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 295.0
HKD2_k127_5723084_6 Glycosyl hydrolases family 15 - - - 0.00000000000000000000000000000000000000000000000000001989 193.0
HKD2_k127_5723084_7 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000014 180.0
HKD2_k127_5723084_8 Multisubunit Na H antiporter MnhC subunit K05567 - - 0.00000000000000000000000008682 116.0
HKD2_k127_5723084_9 TrkA-C domain K07228 - - 0.0000000002552 69.0
HKD2_k127_5743314_0 Carbamoyltransferase K00612 - - 6.573e-261 824.0
HKD2_k127_5743314_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 467.0
HKD2_k127_5743314_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 434.0
HKD2_k127_5743314_3 clavaminate synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 418.0
HKD2_k127_5743314_4 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001577 256.0
HKD2_k127_5743314_5 Major Facilitator Superfamily - - - 0.000000000000000000000000001262 116.0
HKD2_k127_5743314_7 Protein of unknown function (DUF2630) - - - 0.00000000000000002345 85.0
HKD2_k127_5763558_0 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 445.0
HKD2_k127_5763558_1 PFAM metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 406.0
HKD2_k127_5763558_2 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000001746 207.0
HKD2_k127_5763558_3 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000009762 175.0
HKD2_k127_5763558_4 Protein of unknown function (DUF4232) - - - 0.0000001271 61.0
HKD2_k127_5763558_5 Phage integrase, N-terminal SAM-like domain - - - 0.0000003198 57.0
HKD2_k127_5763558_6 DDE superfamily endonuclease - - - 0.00002976 46.0
HKD2_k127_5767378_0 lysine 2,3-aminomutase - - - 2.95e-196 637.0
HKD2_k127_5767378_1 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 546.0
HKD2_k127_5767378_10 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008681 242.0
HKD2_k127_5767378_11 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000003713 225.0
HKD2_k127_5767378_12 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000881 211.0
HKD2_k127_5767378_13 Putative transposase of IS4/5 family (DUF4096) - - - 0.0000000000000000000000000000000000000000000000000000000007948 203.0
HKD2_k127_5767378_14 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000008662 194.0
HKD2_k127_5767378_15 Transposase K07492 - - 0.0000000000000000000000000004783 114.0
HKD2_k127_5767378_16 PFAM transposase IS4 family protein K07492 - - 0.00000000000000000003779 92.0
HKD2_k127_5767378_17 Transposase K07492 - - 0.0000000003911 67.0
HKD2_k127_5767378_18 DDE superfamily endonuclease - - - 0.000000003523 57.0
HKD2_k127_5767378_19 - - - - 0.0000001084 63.0
HKD2_k127_5767378_2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 502.0
HKD2_k127_5767378_20 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0002285 50.0
HKD2_k127_5767378_21 Winged helix-turn helix - - - 0.0002356 43.0
HKD2_k127_5767378_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 457.0
HKD2_k127_5767378_4 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 449.0
HKD2_k127_5767378_5 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 445.0
HKD2_k127_5767378_6 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 409.0
HKD2_k127_5767378_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 398.0
HKD2_k127_5767378_8 Acetyltransferase (GNAT) domain K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 388.0
HKD2_k127_5767378_9 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003073 286.0
HKD2_k127_5898425_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 5.585e-251 784.0
HKD2_k127_5898425_1 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 509.0
HKD2_k127_5898425_10 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000008069 147.0
HKD2_k127_5898425_11 ribonuclease inhibitor activity - - - 0.00000000000000000000000000000001715 138.0
HKD2_k127_5898425_12 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000003409 90.0
HKD2_k127_5898425_13 Drug exporters of the RND superfamily K06994 - - 0.00000006065 59.0
HKD2_k127_5898425_14 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000007049 49.0
HKD2_k127_5898425_2 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 502.0
HKD2_k127_5898425_3 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 311.0
HKD2_k127_5898425_4 PFAM transposase IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 296.0
HKD2_k127_5898425_5 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000435 269.0
HKD2_k127_5898425_6 Transcriptional regulator K05799 - - 0.00000000000000000000000000000000000000000000000000000004569 206.0
HKD2_k127_5898425_7 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000306 179.0
HKD2_k127_5898425_8 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000002005 181.0
HKD2_k127_5898425_9 Cupin domain - - - 0.00000000000000000000000000000000000000000007316 174.0
HKD2_k127_591195_0 Domain of unknown function (DUF2088) - - - 9.558e-296 912.0
HKD2_k127_591195_1 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 4.847e-285 887.0
HKD2_k127_591195_2 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 556.0
HKD2_k127_591195_3 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 363.0
HKD2_k127_591195_4 PIN domain - - - 0.000000000000000000000000000000000000001057 154.0
HKD2_k127_591195_5 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000007103 85.0
HKD2_k127_5936410_0 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 317.0
HKD2_k127_5936410_1 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000004509 205.0
HKD2_k127_5936410_2 Glycosyl transferase family 21 - - - 0.00000000000000000000000004112 125.0
HKD2_k127_5945819_0 Uncharacterised conserved protein (DUF2156) K04567,K14205 - 2.3.2.3,6.1.1.6 1.065e-247 785.0
HKD2_k127_5945819_1 FAD linked oxidase domain protein K16653 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576 1.1.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 600.0
HKD2_k127_5945819_10 PFAM binding-protein-dependent transport systems inner membrane component K05846 - - 0.000000000000000000000000000000000000000000000000000000000000003375 224.0
HKD2_k127_5945819_11 Glycine betaine K05845 - - 0.000000000000000000000000000000000000000000000000000000000000003687 238.0
HKD2_k127_5945819_12 DNA binding domain - - - 0.0000000000000000000000000000000000000000000000000000005333 196.0
HKD2_k127_5945819_13 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000000000000001567 209.0
HKD2_k127_5945819_14 PIN domain - - - 0.00000000000000000000000000000000000000000000000000001034 191.0
HKD2_k127_5945819_15 Protein of unknown function (DUF3180) - - - 0.0000000000000000000000000000000000000000000000002375 187.0
HKD2_k127_5945819_16 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K13940 GO:0008150,GO:0040007 1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000005047 145.0
HKD2_k127_5945819_17 - - - - 0.000000000000000000000004229 103.0
HKD2_k127_5945819_2 ABC transporter K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 524.0
HKD2_k127_5945819_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 381.0
HKD2_k127_5945819_4 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 355.0
HKD2_k127_5945819_5 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 341.0
HKD2_k127_5945819_6 PIN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001835 262.0
HKD2_k127_5945819_7 UbiA prenyltransferase family K14136 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016763,GO:0031224,GO:0031226,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046872,GO:0052636,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000002534 265.0
HKD2_k127_5945819_8 ABC transporter (Permease) K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000007148 241.0
HKD2_k127_5945819_9 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) K16652 - 1.1.1.333 0.000000000000000000000000000000000000000000000000000000000000000004734 234.0
HKD2_k127_6023721_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 - 3.3.1.1 4.501e-240 747.0
HKD2_k127_6023721_1 - - - - 0.00000000000000000000008456 101.0
HKD2_k127_6023721_2 PFAM glycosyl transferase, family 51 - - - 0.00005305 49.0
HKD2_k127_6032438_0 FAD dependent oxidoreductase K15736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 573.0
HKD2_k127_6032438_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 368.0
HKD2_k127_6032438_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 331.0
HKD2_k127_6032438_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 310.0
HKD2_k127_6032438_4 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001948 281.0
HKD2_k127_6032438_5 Protease prsW family - - - 0.000000000000000000000000000000000000000000000000000000000000000001656 236.0
HKD2_k127_6032438_6 Putative esterase - - - 0.0000000000000000000000000000000000000000514 162.0
HKD2_k127_6032438_7 Universal stress protein family - - - 0.0000000000000000000000000000156 124.0
HKD2_k127_6032438_8 - - - - 0.0000029 55.0
HKD2_k127_6034726_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 1.807e-204 658.0
HKD2_k127_6034726_1 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 406.0
HKD2_k127_6034726_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 344.0
HKD2_k127_6034726_3 His Kinase A (phosphoacceptor) domain K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001314 228.0
HKD2_k127_6034726_4 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000000000000000000003483 151.0
HKD2_k127_6063901_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 4.272e-256 803.0
HKD2_k127_6063901_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K14215,K21273 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 356.0
HKD2_k127_6063901_2 pyridoxamine 5-phosphate K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000001766 244.0
HKD2_k127_6063901_3 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000004293 202.0
HKD2_k127_6063901_4 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding - - - 0.0000000000000000000000000000000000000000000000000003474 190.0
HKD2_k127_6063901_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000004155 89.0
HKD2_k127_6063901_6 - - - - 0.00000000001472 70.0
HKD2_k127_6099980_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 522.0
HKD2_k127_6099980_1 SnoaL-like domain K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008907 404.0
HKD2_k127_6099980_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 315.0
HKD2_k127_6099980_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 313.0
HKD2_k127_6099980_4 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000003647 196.0
HKD2_k127_6099980_5 ABC transporter (Permease) K01992 - - 0.0000000000000000000000000000000000000004272 152.0
HKD2_k127_6099980_6 ABC transporter K02003 - - 0.0000000000000001204 82.0
HKD2_k127_6099980_7 YCII-related domain - - - 0.0000000000000618 83.0
HKD2_k127_6145197_0 Predicted membrane protein (DUF2142) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 327.0
HKD2_k127_6145197_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 321.0
HKD2_k127_6145197_10 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0008264 43.0
HKD2_k127_6145197_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000007109 209.0
HKD2_k127_6145197_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000004162 181.0
HKD2_k127_6145197_4 Winged helix-turn helix - - - 0.0000000000000000000000000003886 123.0
HKD2_k127_6145197_5 Winged helix-turn helix - - - 0.00000000000000004855 86.0
HKD2_k127_6145197_6 Predicted membrane protein (DUF2142) - - - 0.0000000000000003413 81.0
HKD2_k127_6145197_7 Predicted membrane protein (DUF2142) - - - 0.00000000000000717 87.0
HKD2_k127_6145197_8 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000002581 82.0
HKD2_k127_6145197_9 Transposase - - - 0.00001206 47.0
HKD2_k127_6184448_0 peptidase U62, modulator of DNA gyrase K03568 - - 7.688e-263 816.0
HKD2_k127_6184448_1 Putative modulator of DNA gyrase - - - 6.548e-194 637.0
HKD2_k127_6184448_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 478.0
HKD2_k127_6184448_3 Protein of unknown function (DUF2587) - GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000007206 227.0
HKD2_k127_6184448_4 - - - - 0.0000000000000000000000000000000002816 139.0
HKD2_k127_6184448_5 HAD-superfamily hydrolase, subfamily IIB - - - 0.00000000000000000000000000006268 117.0
HKD2_k127_6200546_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 423.0
HKD2_k127_6200546_1 S-adenosyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 366.0
HKD2_k127_6200546_2 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000000000000000000000000000000007348 212.0
HKD2_k127_6200546_3 PFAM regulatory protein, MarR - - - 0.000000000000000000000000000000000000000001171 173.0
HKD2_k127_6200546_4 PFAM OsmC family protein - - - 0.000000000001341 68.0
HKD2_k127_6365390_0 PFAM Magnesium chelatase, ChlI subunit K07391 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 1.402e-216 687.0
HKD2_k127_6365390_1 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000006804 132.0
HKD2_k127_6365390_2 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000003937 134.0
HKD2_k127_6365390_3 Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000002269 78.0
HKD2_k127_6381578_0 Cystathionine beta-synthase K01697 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 4.2.1.22 4.052e-248 771.0
HKD2_k127_6381578_1 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 590.0
HKD2_k127_6381578_2 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 501.0
HKD2_k127_6381578_3 Bax inhibitor 1 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 383.0
HKD2_k127_6381578_4 Protein of unknown function (DUF459) K09795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 303.0
HKD2_k127_6381578_5 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000001007 220.0
HKD2_k127_6381578_6 Hydrogenase expression formation protein K04653 - - 0.00000000000000000000000000007991 118.0
HKD2_k127_6381578_7 Domain of unknown function (DUF4287) - - - 0.00000000000000000000000000453 117.0
HKD2_k127_6381578_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000001764 104.0
HKD2_k127_6381578_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000002257 91.0
HKD2_k127_6382819_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 4.738e-226 717.0
HKD2_k127_6382819_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 317.0
HKD2_k127_6382819_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000000000003365 197.0
HKD2_k127_6382819_3 phosphoglycerate mutase K01834,K22306 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237 3.1.3.85,5.4.2.11 0.00000000000000000000000000000000000001588 154.0
HKD2_k127_6382819_4 dehydrogenase complex catalyzes the overall conversion of - - - 0.00000000000000000000006694 104.0
HKD2_k127_6414620_0 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 514.0
HKD2_k127_6414620_1 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008263 270.0
HKD2_k127_6414620_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000007645 129.0
HKD2_k127_6421074_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 1.939e-232 724.0
HKD2_k127_6421074_1 SurA N-terminal domain - - - 0.00000000000000000000000000000000000000000000002531 183.0
HKD2_k127_6421074_2 MazG nucleotide pyrophosphohydrolase domain K02428,K02499 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.00000000000002309 81.0
HKD2_k127_6431954_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 563.0
HKD2_k127_6431954_1 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 392.0
HKD2_k127_6431954_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 387.0
HKD2_k127_6431954_3 Methyltransferase - - - 0.000000000000000000000000000000000000001665 171.0
HKD2_k127_6431954_4 DoxX family - - - 0.00000000000000000000000006066 116.0
HKD2_k127_6431954_5 Alpha/beta hydrolase family - - - 0.0000000000000000000002044 112.0
HKD2_k127_6431954_6 FtsX-like permease family K02004 - - 0.0000000000000000002788 94.0
HKD2_k127_6431954_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000333 93.0
HKD2_k127_6431954_8 Transcriptional regulator - - - 0.00001587 56.0
HKD2_k127_6431954_9 Haem-degrading - - - 0.0008796 48.0
HKD2_k127_6457150_0 ATP-dependent DNA helicase K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 587.0
HKD2_k127_6457150_1 carboxyl transferase K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 469.0
HKD2_k127_6457150_2 Lipase (class 2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 338.0
HKD2_k127_6457150_3 Cobalamin B12-binding K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000001027 241.0
HKD2_k127_6457150_4 peptidase K21471 - - 0.0000000000000000000000000000000000000000000000000000000000009075 220.0
HKD2_k127_6471040_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1137.0
HKD2_k127_6471040_1 SAICAR synthetase K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 461.0
HKD2_k127_6471040_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 363.0
HKD2_k127_6471040_3 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000000000000000000000003736 174.0
HKD2_k127_6471040_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000003251 124.0
HKD2_k127_6482935_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 533.0
HKD2_k127_6482935_1 Monogalactosyldiacylglycerol (MGDG) synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 477.0
HKD2_k127_6482935_10 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000632 186.0
HKD2_k127_6482935_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000001118 149.0
HKD2_k127_6482935_12 protein methyltransferase activity - - - 0.00000000000000000000000000000000000002239 158.0
HKD2_k127_6482935_13 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000001851 133.0
HKD2_k127_6482935_14 spore germination - - - 0.000000000000000000000023 117.0
HKD2_k127_6482935_15 Bacterial PH domain - - - 0.00001414 56.0
HKD2_k127_6482935_2 TIGRFAM KamA family protein K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 460.0
HKD2_k127_6482935_3 Epimerase dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 403.0
HKD2_k127_6482935_4 PFAM Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 362.0
HKD2_k127_6482935_5 Two component transcriptional regulator, LuxR family K07695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009722 259.0
HKD2_k127_6482935_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001587 258.0
HKD2_k127_6482935_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001125 274.0
HKD2_k127_6482935_8 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001156 243.0
HKD2_k127_6482935_9 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000009321 194.0
HKD2_k127_6482990_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 9.532e-251 783.0
HKD2_k127_6482990_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.181e-220 718.0
HKD2_k127_6482990_2 homoserine dehydrogenase K00003,K12524 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 408.0
HKD2_k127_6482990_3 type I restriction enzyme K07504 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 376.0
HKD2_k127_6482990_4 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000001286 199.0
HKD2_k127_6482990_5 PFAM Transposase, mutator type - - - 0.000000000000000000000000000000000000000000000000002766 186.0
HKD2_k127_6482990_6 - - - - 0.00000000000000000000000000000000000000000000000007782 191.0
HKD2_k127_6482990_7 DNA methylAse K07445 - - 0.000000000000000000000000000005055 126.0
HKD2_k127_6482990_8 Recombinase - - - 0.0000009881 50.0
HKD2_k127_6482992_0 glycyl-radical enzyme activating activity K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 539.0
HKD2_k127_6482992_1 defense response to virus K19091 - - 0.000000000000000000000000000000000000000000000000000000001973 210.0
HKD2_k127_6482992_2 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.0000000000000000000000000000000000000000008269 173.0
HKD2_k127_6482992_3 RNA-directed DNA polymerase K00986 - 2.7.7.49 0.000000000000000000000000000000000000000005885 169.0
HKD2_k127_6482992_6 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.0001373 48.0
HKD2_k127_6489721_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.738e-282 884.0
HKD2_k127_6489721_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 416.0
HKD2_k127_6489721_2 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 309.0
HKD2_k127_6489721_3 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000004885 199.0
HKD2_k127_6489721_4 PIN domain - - - 0.0000000000000000000000002 113.0
HKD2_k127_6489721_5 Histidine kinase - - - 0.000000000000000000000001203 111.0
HKD2_k127_6489721_6 Ribbon-helix-helix protein, copG family - - - 0.00000000000001117 76.0
HKD2_k127_6508249_0 Histidine kinase - - - 5.141e-206 673.0
HKD2_k127_6508249_1 aldo keto reductase K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 505.0
HKD2_k127_6508249_10 PFAM helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000000003778 164.0
HKD2_k127_6508249_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000001586 156.0
HKD2_k127_6508249_12 Thermolysin metallopeptidase, catalytic domain - - - 0.000000000000000000000000000000002163 130.0
HKD2_k127_6508249_14 Protein of unknown function (DUF742) - - - 0.0000000000000000000000001871 109.0
HKD2_k127_6508249_15 FCD - - - 0.00000000000000000000001836 105.0
HKD2_k127_6508249_16 - - - - 0.0000000000007348 79.0
HKD2_k127_6508249_17 FCD - - - 0.00000001402 57.0
HKD2_k127_6508249_2 Thiolase, C-terminal domain K00632 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 480.0
HKD2_k127_6508249_3 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 438.0
HKD2_k127_6508249_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 323.0
HKD2_k127_6508249_5 Thermolysin metallopeptidase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 297.0
HKD2_k127_6508249_6 ATP- GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 286.0
HKD2_k127_6508249_7 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000861 266.0
HKD2_k127_6508249_8 Roadblock/LC7 domain K07131 - - 0.000000000000000000000000000000000000000000000000000000000000005178 218.0
HKD2_k127_6508249_9 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000008849 179.0
HKD2_k127_6509809_0 CRISPR-associated helicase Cas3 K07012 - - 2.997e-245 788.0
HKD2_k127_6509809_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 9.041e-219 705.0
HKD2_k127_6509809_10 PFAM Rieske 2Fe-2S K05710 - - 0.000000000000000000000000000000000000001309 159.0
HKD2_k127_6509809_11 toxic component of a K07065 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000002133 138.0
HKD2_k127_6509809_12 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.00000000000000000000000002716 110.0
HKD2_k127_6509809_13 Putative restriction endonuclease - - - 0.00000000000000006177 87.0
HKD2_k127_6509809_2 FeS assembly protein SufD K09015 GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 563.0
HKD2_k127_6509809_3 FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 422.0
HKD2_k127_6509809_4 CRISPR-associated protein GSU0053 (Cas_GSU0053) K19131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 419.0
HKD2_k127_6509809_5 TIGRFAM FeS assembly protein SufB K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 396.0
HKD2_k127_6509809_6 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) K19132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 385.0
HKD2_k127_6509809_7 - K19136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000181 304.0
HKD2_k127_6509809_8 TIGRFAM SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002416 260.0
HKD2_k127_6509809_9 Pfam:DUF59 - - - 0.000000000000000000000000000000000000000000000000000001978 201.0
HKD2_k127_6516586_0 Phytanoyl-CoA dioxygenase (PhyH) K15650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001383 285.0
HKD2_k127_6516586_1 TfuA-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003971 244.0
HKD2_k127_6516586_2 YcaO cyclodehydratase, ATP-ad Mg2+-binding - - - 0.0000000000000000000000000000000000000000000000001446 181.0
HKD2_k127_6516586_3 required for the transposition of insertion element IS2404 - - - 0.000005682 48.0
HKD2_k127_6521290_0 synthetase K01895 - 6.2.1.1 3.056e-246 775.0
HKD2_k127_6521290_1 Aldehyde dehydrogenase K00128,K00130 - 1.2.1.3,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 597.0
HKD2_k127_6521290_10 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 382.0
HKD2_k127_6521290_11 PFAM Acyl transferase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 361.0
HKD2_k127_6521290_12 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 343.0
HKD2_k127_6521290_13 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001167 290.0
HKD2_k127_6521290_14 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005603 282.0
HKD2_k127_6521290_15 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000001358 196.0
HKD2_k127_6521290_16 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000015 148.0
HKD2_k127_6521290_17 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000009824 125.0
HKD2_k127_6521290_18 Malonate decarboxylase gamma subunit (MdcE) K18472 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009317,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019367,GO:0019752,GO:0030312,GO:0030497,GO:0032787,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:0072330,GO:1901575,GO:1901576,GO:1902494 2.1.3.15,6.4.1.2,6.4.1.3 0.0000000000000000000000009683 120.0
HKD2_k127_6521290_19 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000000000000000000006537 100.0
HKD2_k127_6521290_2 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 603.0
HKD2_k127_6521290_20 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000002548 73.0
HKD2_k127_6521290_21 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000003819 63.0
HKD2_k127_6521290_3 PFAM carboxyl transferase K18472 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009317,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019367,GO:0019752,GO:0030312,GO:0030497,GO:0032787,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:0072330,GO:1901575,GO:1901576,GO:1902494 2.1.3.15,6.4.1.2,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 530.0
HKD2_k127_6521290_4 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 520.0
HKD2_k127_6521290_5 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 487.0
HKD2_k127_6521290_6 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 479.0
HKD2_k127_6521290_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 469.0
HKD2_k127_6521290_8 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 443.0
HKD2_k127_6521290_9 e3 binding domain K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 398.0
HKD2_k127_6530471_0 Rhamnulose-1-phosphate aldolase alcohol dehydrogenase K00068 - 1.1.1.140 3.312e-253 797.0
HKD2_k127_6530471_1 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 401.0
HKD2_k127_6530471_2 Initiation factor 2 subunit family K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 380.0
HKD2_k127_6530471_3 Putative exonuclease SbcCD, C subunit - - - 0.0000000000000000000000000000000000000003476 158.0
HKD2_k127_6530471_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000000000000000000000001774 130.0
HKD2_k127_6530471_5 Transposase DDE domain - - - 0.0000000000000000000000000002346 119.0
HKD2_k127_6530471_6 Protein of unknown function C-terminus (DUF2399) - - - 0.00000000000000009784 93.0
HKD2_k127_6530471_7 Protein of unknown function N-terminus (DUF3323) - - - 0.0000001147 57.0
HKD2_k127_6530471_8 Protein of unknown function N-terminus (DUF3323) - - - 0.0000001728 54.0
HKD2_k127_6538077_0 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 352.0
HKD2_k127_6538077_1 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000000002503 226.0
HKD2_k127_6538077_2 Belongs to the UPF0336 family - - - 0.0000000000000000000000000000000001144 135.0
HKD2_k127_6538077_3 viral genome integration into host DNA - - - 0.0000000006432 70.0
HKD2_k127_6538077_4 Transposase - - - 0.00001206 47.0
HKD2_k127_6538478_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1537.0
HKD2_k127_6538478_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 460.0
HKD2_k127_6538478_10 - - - - 0.000000006681 61.0
HKD2_k127_6538478_11 Transposase - - - 0.00000001187 58.0
HKD2_k127_6538478_13 Transcriptional regulator, TraR DksA family K06204 - - 0.00004342 49.0
HKD2_k127_6538478_14 HEPN domain - - - 0.0002171 48.0
HKD2_k127_6538478_2 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 431.0
HKD2_k127_6538478_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 398.0
HKD2_k127_6538478_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 394.0
HKD2_k127_6538478_5 protein acetylation K02348,K03828 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000136 301.0
HKD2_k127_6538478_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000007606 218.0
HKD2_k127_6538478_7 phosphoribosyl-ATP diphosphatase activity - - - 0.000000000000000000000000000000000000008033 165.0
HKD2_k127_6538478_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000314 82.0
HKD2_k127_6538478_9 sequence-specific DNA binding - - - 0.000000005094 67.0
HKD2_k127_655831_0 von Willebrand factor type A - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 9.103e-317 1006.0
HKD2_k127_655831_1 Mg-chelatase subunit ChlI K03405 - 6.6.1.1 3.725e-240 795.0
HKD2_k127_655831_10 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 315.0
HKD2_k127_655831_11 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 310.0
HKD2_k127_655831_12 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000003347 246.0
HKD2_k127_655831_13 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000004118 229.0
HKD2_k127_655831_14 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000003617 135.0
HKD2_k127_655831_15 PFAM Tellurite resistance K05793 - - 0.0000000000001015 76.0
HKD2_k127_655831_2 2-methylcitrate dehydratase K01720 - 4.2.1.79 6.111e-194 636.0
HKD2_k127_655831_3 4-hydroxyphenylpyruvate dioxygenase K00457 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 594.0
HKD2_k127_655831_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 569.0
HKD2_k127_655831_5 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 509.0
HKD2_k127_655831_6 A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics K18455 GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 476.0
HKD2_k127_655831_7 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 423.0
HKD2_k127_655831_8 Belongs to the citrate synthase family K01647,K01659 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0071704 2.3.3.1,2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 418.0
HKD2_k127_655831_9 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 378.0
HKD2_k127_6610641_0 Glucodextranase, domain N K01178 - 3.2.1.3 0.0 1219.0
HKD2_k127_6610641_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 433.0
HKD2_k127_6610641_10 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000009729 190.0
HKD2_k127_6610641_11 Belongs to the UPF0753 family K09822 - - 0.00000000000000000000000000000000002534 139.0
HKD2_k127_6610641_12 Uncharacterized ACR, COG1993 - - - 0.000000000000000000000000000006012 140.0
HKD2_k127_6610641_13 Domain of unknown function (DUF4276) - - - 0.00006582 50.0
HKD2_k127_6610641_2 Belongs to the UPF0753 family K09822 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 398.0
HKD2_k127_6610641_3 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 427.0
HKD2_k127_6610641_4 Inositol monophosphatase K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 368.0
HKD2_k127_6610641_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 322.0
HKD2_k127_6610641_6 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000164 287.0
HKD2_k127_6610641_7 Bacterial transferase hexapeptide (six repeats) K02617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007006 276.0
HKD2_k127_6610641_8 Aconitate hydratase 1 K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002113 252.0
HKD2_k127_6610641_9 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004145 244.0
HKD2_k127_6612320_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 2.029e-221 698.0
HKD2_k127_6612320_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 589.0
HKD2_k127_6612320_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 369.0
HKD2_k127_6612320_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000006429 212.0
HKD2_k127_6612320_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000009504 199.0
HKD2_k127_6612320_5 - - - - 0.000000000000000000000000000000000000000000008512 173.0
HKD2_k127_6612320_6 Cold shock protein K03704 - - 0.00000000000000000000000000000005782 125.0
HKD2_k127_6617432_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 434.0
HKD2_k127_6617432_1 lipopolysaccharide transmembrane transporter activity K07058 - - 0.0000000000000000000000000000000000000000000000000000000000005334 222.0
HKD2_k127_6617432_2 lipopolysaccharide transmembrane transporter activity K07058 - - 0.0000000000000001322 80.0
HKD2_k127_6626134_0 CBS domain containing protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 584.0
HKD2_k127_6626134_1 PFAM PhoH family protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 538.0
HKD2_k127_6626134_10 membrane protein (DUF2078) K08982 - - 0.00000000000002943 76.0
HKD2_k127_6626134_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 494.0
HKD2_k127_6626134_3 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 302.0
HKD2_k127_6626134_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000000000000000006471 218.0
HKD2_k127_6626134_5 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000142 199.0
HKD2_k127_6626134_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000003288 189.0
HKD2_k127_6626134_7 Pro-kumamolisin, activation domain K08677 - - 0.0000000000000000000000000000000000000000000003552 190.0
HKD2_k127_6626134_8 cytidine deaminase - - - 0.000000000000000000000000000000000005579 150.0
HKD2_k127_6626134_9 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000001645 111.0
HKD2_k127_6656077_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.8 5.594e-220 689.0
HKD2_k127_6656077_1 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 427.0
HKD2_k127_6656077_2 protein serine/threonine phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000857 276.0
HKD2_k127_6656077_3 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000000000000000000000000001321 222.0
HKD2_k127_6656077_4 Protein of unknown function (DUF3499) - - - 0.0000000000000000000000000000000002724 133.0
HKD2_k127_6656077_5 Trm112p-like protein K09791 - - 0.000000000000000001857 86.0
HKD2_k127_6676713_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1199.0
HKD2_k127_6676713_1 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 5e-324 1006.0
HKD2_k127_6676713_2 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 5.16e-205 640.0
HKD2_k127_6676713_3 Mur ligase, middle domain protein K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 3.476e-204 647.0
HKD2_k127_6676713_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 559.0
HKD2_k127_6676713_5 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 355.0
HKD2_k127_6676713_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000008799 232.0
HKD2_k127_6676713_7 rod shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000004455 147.0
HKD2_k127_6676713_8 - - - - 0.00000000000000000000000000000005685 135.0
HKD2_k127_6676713_9 Major facilitator Superfamily - - - 0.0000001478 64.0
HKD2_k127_6742997_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 615.0
HKD2_k127_6742997_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 423.0
HKD2_k127_6742997_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 375.0
HKD2_k127_6742997_3 Aminoglycoside 2'-N-acetyltransferase K17840 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0034069,GO:0044237,GO:0044248,GO:0044464,GO:0047921,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 2.3.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000006477 245.0
HKD2_k127_6742997_4 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000001956 217.0
HKD2_k127_6742997_5 transcriptional regulator - - - 0.000000000000000000000000000001199 141.0
HKD2_k127_6743119_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 537.0
HKD2_k127_6743119_1 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000663 203.0
HKD2_k127_6743119_2 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.00000000003459 68.0
HKD2_k127_6743119_3 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000003511 60.0
HKD2_k127_6768567_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 1.458e-293 919.0
HKD2_k127_6768567_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.341e-261 811.0
HKD2_k127_6768567_10 GTP binding - - - 0.000000000002311 73.0
HKD2_k127_6768567_11 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000001263 62.0
HKD2_k127_6768567_13 transposase activity - - - 0.000003205 51.0
HKD2_k127_6768567_2 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 563.0
HKD2_k127_6768567_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 326.0
HKD2_k127_6768567_4 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000003237 267.0
HKD2_k127_6768567_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000001015 155.0
HKD2_k127_6768567_6 Transposase - - - 0.00000000000000000000000000000000008598 142.0
HKD2_k127_6768567_7 Transposase DDE domain group 1 - - - 0.00000000000000000000000002712 117.0
HKD2_k127_6768567_8 2'-5' RNA ligase superfamily - - - 0.00000000000000000005438 91.0
HKD2_k127_6768567_9 competence protein - - - 0.000000000000006076 80.0
HKD2_k127_679221_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 0.0 1375.0
HKD2_k127_679221_1 DEAD DEAH box helicase K06877 - - 0.0 1095.0
HKD2_k127_679221_10 Filamentation induced by cAMP protein fic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001478 267.0
HKD2_k127_679221_11 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001122 244.0
HKD2_k127_679221_12 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000002351 207.0
HKD2_k127_679221_13 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000000000000000000000000000007061 183.0
HKD2_k127_679221_14 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000000000000000000000000000002002 160.0
HKD2_k127_679221_15 - - - - 0.0000000000000000000000000000000000000002032 157.0
HKD2_k127_679221_16 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000000000000000002463 157.0
HKD2_k127_679221_17 Type ii secretion system K12510 - - 0.00000000000000000000000000008044 132.0
HKD2_k127_679221_18 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000002086 113.0
HKD2_k127_679221_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1024.0
HKD2_k127_679221_20 - - - - 0.00000000000000001695 89.0
HKD2_k127_679221_21 Protein of unknown function (DUF4244) - - - 0.0000000003583 67.0
HKD2_k127_679221_22 TIGRFAM helicase secretion neighborhood TadE-like protein - - - 0.0001926 51.0
HKD2_k127_679221_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 2.338e-261 822.0
HKD2_k127_679221_4 PFAM Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 492.0
HKD2_k127_679221_5 DNA polymerase III, delta' K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 474.0
HKD2_k127_679221_6 Type ii secretion system protein e K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 458.0
HKD2_k127_679221_7 bacterial-type flagellum organization - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 368.0
HKD2_k127_679221_8 HAD-superfamily subfamily IB hydrolase, TIGR01490 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 335.0
HKD2_k127_679221_9 Colicin V production protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 314.0
HKD2_k127_681829_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 480.0
HKD2_k127_681829_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 394.0
HKD2_k127_681829_2 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 361.0
HKD2_k127_681829_3 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 340.0
HKD2_k127_681829_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 334.0
HKD2_k127_681829_5 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 313.0
HKD2_k127_681829_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 307.0
HKD2_k127_681829_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000002958 194.0
HKD2_k127_681829_8 PFAM peptidase - - - 0.000000000000000000000000000000000002773 155.0
HKD2_k127_6835799_0 Peptidase family S49 K04773,K04774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 621.0
HKD2_k127_6835799_1 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000001767 196.0
HKD2_k127_6835799_2 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000003558 105.0
HKD2_k127_6835799_3 PFAM glycoside hydrolase family 39 - - - 0.0000000000004182 77.0
HKD2_k127_6835799_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000005554 51.0
HKD2_k127_6840615_0 Belongs to the glycosyl hydrolase 57 family K16149 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.4.1.18 9.602e-213 676.0
HKD2_k127_6840615_1 PFAM Glycosyl transferase, group 1 K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 340.0
HKD2_k127_6840615_2 PFAM Methyltransferase domain K00568 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008051 279.0
HKD2_k127_6887538_0 Transcriptional regulator - - - 0.0000000000000000000002352 102.0
HKD2_k127_6887538_1 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000001053 61.0
HKD2_k127_6887538_2 - - - - 0.0004414 48.0
HKD2_k127_6898738_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1083.0
HKD2_k127_6898738_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.17.4.1 6.485e-278 861.0
HKD2_k127_6898738_10 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 321.0
HKD2_k127_6898738_11 polar amino acid ABC transporter, inner membrane subunit K10007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 319.0
HKD2_k127_6898738_12 EAL domain - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009187,GO:0009214,GO:0009987,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042578,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0046434,GO:0046483,GO:0046700,GO:0051704,GO:0055086,GO:0071111,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 301.0
HKD2_k127_6898738_13 polar amino acid ABC transporter, inner membrane subunit K10006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001922 267.0
HKD2_k127_6898738_14 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000006466 242.0
HKD2_k127_6898738_15 ferrous iron binding - - - 0.0000000000000000000000000000000000000000000000000000000000000005439 240.0
HKD2_k127_6898738_16 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000003971 165.0
HKD2_k127_6898738_17 Protein of unknown function (DUF3046) - - - 0.00000000000000000000002387 102.0
HKD2_k127_6898738_18 PFAM Extracellular solute-binding protein, family 3 K10005 - - 0.0000000000000000004492 87.0
HKD2_k127_6898738_19 Lysin motif - - - 0.0005772 49.0
HKD2_k127_6898738_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.07e-232 734.0
HKD2_k127_6898738_3 Endoribonuclease that initiates mRNA decay K18682 - - 3.756e-231 733.0
HKD2_k127_6898738_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 4.641e-215 679.0
HKD2_k127_6898738_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 9.137e-195 612.0
HKD2_k127_6898738_6 PFAM ABC transporter K10008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 387.0
HKD2_k127_6898738_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 405.0
HKD2_k127_6898738_8 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 355.0
HKD2_k127_6898738_9 PFAM Extracellular solute-binding protein, family 3 K10005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007984 325.0
HKD2_k127_6905290_0 ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 1.707e-221 709.0
HKD2_k127_6905290_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 307.0
HKD2_k127_6905290_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000001403 237.0
HKD2_k127_691204_0 PFAM Peptidase M1, membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 0.0 1311.0
HKD2_k127_691204_1 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 1.946e-241 769.0
HKD2_k127_691204_10 - - - - 0.000004731 59.0
HKD2_k127_691204_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 384.0
HKD2_k127_691204_3 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 308.0
HKD2_k127_691204_4 PFAM Ribose galactose isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000003209 230.0
HKD2_k127_691204_5 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding - - - 0.00000000000000000000000000000000000000000000000002672 185.0
HKD2_k127_691204_6 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000007235 152.0
HKD2_k127_691204_7 Domain of unknown function (DUF5130) - - - 0.0000000000000000000000000000000000001818 149.0
HKD2_k127_691204_8 - - - - 0.000000000000000000000000009484 114.0
HKD2_k127_691204_9 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000001692 85.0
HKD2_k127_6915030_0 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali - - - 1.454e-212 692.0
HKD2_k127_6915030_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K12141 - - 3.982e-197 625.0
HKD2_k127_6915030_10 NADH dehydrogenase K12138 - - 0.000000000000001067 88.0
HKD2_k127_6915030_11 Uncharacterized ACR, COG1993 K09137 - - 0.00000001204 62.0
HKD2_k127_6915030_12 - - - - 0.00000107 57.0
HKD2_k127_6915030_13 - - - - 0.00003995 50.0
HKD2_k127_6915030_2 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K15830 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 566.0
HKD2_k127_6915030_3 Enolase, N-terminal domain K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 467.0
HKD2_k127_6915030_4 NADH dehydrogenase K12138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 382.0
HKD2_k127_6915030_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 327.0
HKD2_k127_6915030_6 Hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002065 274.0
HKD2_k127_6915030_7 NUDIX domain - - - 0.0000000000000000000000000000000008978 136.0
HKD2_k127_6915030_8 Dynamin family - - - 0.0000000000000000004689 101.0
HKD2_k127_6915030_9 PFAM Dynamin family - - - 0.000000000000000005598 92.0
HKD2_k127_6918765_0 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.45e-218 687.0
HKD2_k127_6918765_1 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 577.0
HKD2_k127_6918765_10 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05524 - - 0.000000000000000000000000000000000000000000000000000000004057 200.0
HKD2_k127_6918765_11 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000002482 175.0
HKD2_k127_6918765_12 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000002842 159.0
HKD2_k127_6918765_13 PFAM Roadblock LC7 K07131 - - 0.00000000000000000000000000000000000002246 147.0
HKD2_k127_6918765_14 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000003104 95.0
HKD2_k127_6918765_15 DNA-binding transcription factor activity K16328 - 2.7.1.83 0.000000000005645 76.0
HKD2_k127_6918765_16 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.0000000003415 72.0
HKD2_k127_6918765_17 - - - - 0.00000001278 68.0
HKD2_k127_6918765_18 - - - - 0.000001171 54.0
HKD2_k127_6918765_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 476.0
HKD2_k127_6918765_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 460.0
HKD2_k127_6918765_4 Peptidase family M28 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 454.0
HKD2_k127_6918765_5 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 362.0
HKD2_k127_6918765_6 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 316.0
HKD2_k127_6918765_7 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 294.0
HKD2_k127_6918765_8 Conserved hypothetical ATP binding protein K06945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007141 248.0
HKD2_k127_6918765_9 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000007312 243.0
HKD2_k127_6927489_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 393.0
HKD2_k127_6927489_1 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 337.0
HKD2_k127_6927489_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 329.0
HKD2_k127_6927489_3 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.000000000000000000000000002961 111.0
HKD2_k127_6927489_4 - - - - 0.000002002 61.0
HKD2_k127_6962540_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 9.675e-217 684.0
HKD2_k127_6962540_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 409.0
HKD2_k127_6962540_2 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000005877 179.0
HKD2_k127_6962540_3 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000001843 177.0
HKD2_k127_6962540_4 Cobalamin B12-binding domain - - - 0.00000000000000000000000000000000000000000001483 180.0
HKD2_k127_6962540_5 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000003838 119.0
HKD2_k127_6962540_6 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000003354 97.0
HKD2_k127_6964820_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 454.0
HKD2_k127_6964820_1 Fusaric acid resistance protein-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 452.0
HKD2_k127_6964820_10 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000003879 233.0
HKD2_k127_6964820_11 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000002718 234.0
HKD2_k127_6964820_12 Belongs to the glycosyl hydrolase 26 family K01218,K01219,K05970,K19355 - 3.1.1.53,3.2.1.78,3.2.1.81 0.000000000000000000000000000000000000000000000000000000000001824 226.0
HKD2_k127_6964820_13 - - - - 0.0000000000000000000000000000000000000000000000000000000002278 215.0
HKD2_k127_6964820_14 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000002539 179.0
HKD2_k127_6964820_15 - - - - 0.00000000000000000000000000000005106 138.0
HKD2_k127_6964820_16 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000555 124.0
HKD2_k127_6964820_17 PIN domain - - - 0.00000000000000000000000171 103.0
HKD2_k127_6964820_18 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.0000000000000000000004301 106.0
HKD2_k127_6964820_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 400.0
HKD2_k127_6964820_20 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000007128 94.0
HKD2_k127_6964820_21 Copper chaperone PCu(A)C - - - 0.0000000000001997 81.0
HKD2_k127_6964820_24 Predicted membrane protein (DUF2254) - - - 0.000006646 58.0
HKD2_k127_6964820_25 Glycosyl transferase family group 2 - - - 0.00005725 48.0
HKD2_k127_6964820_26 HAD-superfamily hydrolase, subfamily IA, variant 1 - - - 0.000127 52.0
HKD2_k127_6964820_27 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.0003813 53.0
HKD2_k127_6964820_28 EamA-like transporter family - - - 0.0006324 48.0
HKD2_k127_6964820_3 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 332.0
HKD2_k127_6964820_4 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 321.0
HKD2_k127_6964820_5 Helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 318.0
HKD2_k127_6964820_6 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 307.0
HKD2_k127_6964820_7 Belongs to the glycosyl hydrolase 26 family K01218,K01219,K05970,K19355 - 3.1.1.53,3.2.1.78,3.2.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000004229 267.0
HKD2_k127_6964820_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001564 248.0
HKD2_k127_6964820_9 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000002194 246.0
HKD2_k127_6995268_0 SMART alpha amylase, catalytic sub domain K01187 - 3.2.1.20 8.419e-201 640.0
HKD2_k127_6995268_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000122 259.0
HKD2_k127_6995268_2 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000003755 78.0
HKD2_k127_7060252_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 5.616e-231 732.0
HKD2_k127_7060252_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000008726 144.0
HKD2_k127_7060252_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000009558 87.0
HKD2_k127_7100556_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 1.892e-273 872.0
HKD2_k127_7100556_1 PFAM ErfK YbiS YcfS YnhG family protein - GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0019538,GO:0030203,GO:0030312,GO:0042546,GO:0043170,GO:0044085,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 441.0
HKD2_k127_7100556_2 L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000001171 210.0
HKD2_k127_7100556_3 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000000000000000002672 171.0
HKD2_k127_7100556_4 antisigma factor binding K04749,K06378 - - 0.00003299 53.0
HKD2_k127_7128186_0 ABC transporter K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 495.0
HKD2_k127_7128186_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001525 282.0
HKD2_k127_7128186_2 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000000000000001102 182.0
HKD2_k127_715787_0 protein phosphatase 2C domain protein - - - 6.752e-258 872.0
HKD2_k127_715787_1 transferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 358.0
HKD2_k127_715787_2 PFAM tRNA rRNA methyltransferase, SpoU - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 351.0
HKD2_k127_715787_3 dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000006665 225.0
HKD2_k127_715787_4 dioxygenase activity - - - 0.0000000000000000000000000000000006004 132.0
HKD2_k127_720744_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 467.0
HKD2_k127_720744_1 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 312.0
HKD2_k127_720744_2 Stage II sporulation - - - 0.000000000000000000000000000000000000000000000000000000008795 226.0
HKD2_k127_720744_3 anti-sigma regulatory factor K17752 - 2.7.11.1 0.00000000000000000000000000000000000000000000005665 174.0
HKD2_k127_720744_4 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000001618 193.0
HKD2_k127_720744_5 manually curated - - - 0.0000000000000003292 78.0
HKD2_k127_720744_6 STAS domain K17762 - - 0.0004362 43.0
HKD2_k127_7242146_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 547.0
HKD2_k127_7242146_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 499.0
HKD2_k127_7242146_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 374.0
HKD2_k127_7242146_3 phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 310.0
HKD2_k127_7244454_0 Catalase K03781 - 1.11.1.6 5.4e-284 890.0
HKD2_k127_7244454_1 Xylulose kinase K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 552.0
HKD2_k127_7244454_10 toxin-antitoxin pair type II binding - - - 0.0000000000007194 79.0
HKD2_k127_7244454_11 Transposase - - - 0.00001206 47.0
HKD2_k127_7244454_2 Belongs to the peptidase S51 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 290.0
HKD2_k127_7244454_3 phosphoglycerate mutase K02226 GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000181 254.0
HKD2_k127_7244454_4 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 239.0
HKD2_k127_7244454_5 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000000000000000000000000000000000000009588 229.0
HKD2_k127_7244454_6 Belongs to the Fur family K03711,K22297 - - 0.00000000000000000000000000000000000000000000000000000000005813 209.0
HKD2_k127_7244454_7 Methylamine utilisation protein MauE - - - 0.000000000000000000000000000000000000000000000000009006 190.0
HKD2_k127_7244454_8 Thioredoxin - - - 0.000000000000000000000000000000000000000000000002065 185.0
HKD2_k127_7244454_9 Protein of unknown function (DUF3618) - - - 0.0000000000000000000008442 101.0
HKD2_k127_7270909_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 449.0
HKD2_k127_7270983_0 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 400.0
HKD2_k127_7270983_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 388.0
HKD2_k127_7270983_2 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 325.0
HKD2_k127_7270983_3 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002516 282.0
HKD2_k127_7270983_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000003625 166.0
HKD2_k127_7270983_5 ABC-type branched-chain amino acid transport K01999 - - 0.000000000000000000000000000000001183 149.0
HKD2_k127_7270983_6 L,D-transpeptidase catalytic domain - - - 0.000000000000004 81.0
HKD2_k127_7270983_8 sequence-specific DNA binding - - - 0.0002673 53.0
HKD2_k127_7305982_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2265.0
HKD2_k127_7305982_1 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 4.717e-264 821.0
HKD2_k127_7305982_2 Response regulator receiver K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 334.0
HKD2_k127_7305982_3 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000005465 172.0
HKD2_k127_7305982_4 ParE toxin of type II toxin-antitoxin system, parDE - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000006036 112.0
HKD2_k127_7305982_5 Antitoxin component of a toxin-antitoxin (TA) module K19159 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.000000000000000001081 95.0
HKD2_k127_7311356_0 ABC transporter, ATP-binding protein K16786,K16787 - - 2.633e-213 689.0
HKD2_k127_7311356_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 1.766e-212 665.0
HKD2_k127_7311356_10 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000598 189.0
HKD2_k127_7311356_11 PFAM Prenyltransferase squalene oxidase - - - 0.0000000000000000000000000000000000000000000006016 183.0
HKD2_k127_7311356_12 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000003468 141.0
HKD2_k127_7311356_13 - - - - 0.00000000000000000000219 98.0
HKD2_k127_7311356_2 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 510.0
HKD2_k127_7311356_3 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 532.0
HKD2_k127_7311356_4 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 473.0
HKD2_k127_7311356_5 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 439.0
HKD2_k127_7311356_6 ABC transporter (Permease) K16927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 321.0
HKD2_k127_7311356_7 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000000008811 244.0
HKD2_k127_7311356_8 Protein of unknown function (DUF3043) - GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - 0.000000000000000000000000000000000000000000000000000000000000000001535 233.0
HKD2_k127_7311356_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000008695 243.0
HKD2_k127_7315625_0 - - - - 0.000000000000000000000000000000000000000000000000000003349 198.0
HKD2_k127_7315625_1 Serine threonine protein kinase - - - 0.00000000000000000000000000000003819 139.0
HKD2_k127_7333376_0 pfam abc K02074,K09820,K11710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 375.0
HKD2_k127_7333376_1 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 373.0
HKD2_k127_7333376_2 PFAM ABC-3 protein K02075,K09816,K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 356.0
HKD2_k127_7333376_3 ABC 3 transport family K02075,K09819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 311.0
HKD2_k127_7333376_4 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000006297 138.0
HKD2_k127_7333376_5 transcriptional K22298 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0044212,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000008238 132.0
HKD2_k127_7333376_6 ABC-type Mn2 Zn2 transport systems permease components - - - 0.000000000000000000000000000000006242 146.0
HKD2_k127_7333376_7 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000009409 118.0
HKD2_k127_7341286_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 563.0
HKD2_k127_7341286_1 Acyltransferase - - - 0.000000000000000000000000000000000000000000000001698 179.0
HKD2_k127_7341286_2 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000005226 171.0
HKD2_k127_7540770_0 Lecithin:cholesterol acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002513 280.0
HKD2_k127_7540770_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000037 229.0
HKD2_k127_7540770_2 Acyltransferase - - - 0.00000000000000000002275 99.0
HKD2_k127_7543113_0 PFAM alpha amylase, catalytic K05341 - 2.4.1.4 0.00000000000000000000000000000000000000000000000000000000505 205.0
HKD2_k127_7543113_1 Dak phosphatase K07030 - - 0.00000000000000000000000000000000001024 153.0
HKD2_k127_7543113_2 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000005761 130.0
HKD2_k127_7543113_3 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000005876 71.0
HKD2_k127_7591590_0 Thioesterase superfamily K18014 - 4.3.1.14 0.000000000000000000000000000000008683 128.0
HKD2_k127_7591590_1 - - - - 0.00000000000000000000000009949 110.0
HKD2_k127_7591590_2 Protein of unknown function (DUF433) - - - 0.00000000000000000000006061 100.0
HKD2_k127_7644050_0 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 304.0
HKD2_k127_7644050_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 304.0
HKD2_k127_7644050_10 peptide deformylase activity K01462 - 3.5.1.88 0.00000000000000000000156 109.0
HKD2_k127_7644050_11 RDD family - - - 0.0005304 52.0
HKD2_k127_7644050_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003663 250.0
HKD2_k127_7644050_3 protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000002296 239.0
HKD2_k127_7644050_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000005922 216.0
HKD2_k127_7644050_5 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000002157 138.0
HKD2_k127_7644050_6 - - - - 0.0000000000000000000000000003918 126.0
HKD2_k127_7644050_7 - - - - 0.000000000000000000000000144 109.0
HKD2_k127_7644050_8 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000306 106.0
HKD2_k127_7644050_9 - - - - 0.000000000000000000001248 110.0
HKD2_k127_7670024_0 Protein of unknown function (DUF445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 518.0
HKD2_k127_7670024_1 GGDEF domain K01768,K02488,K07676,K10715,K20976 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3,2.7.7.65,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 402.0
HKD2_k127_7670024_2 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000007248 173.0
HKD2_k127_7670024_3 IMP dehydrogenase activity - - - 0.00000000000000000000000000000000002721 148.0
HKD2_k127_7670024_4 Predicted membrane protein (DUF2127) - - - 0.00000000000000000000000000000668 121.0
HKD2_k127_7670024_5 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000004711 120.0
HKD2_k127_7670024_6 - - - - 0.000000000001401 81.0
HKD2_k127_7681415_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 1.687e-258 816.0
HKD2_k127_7681415_1 AMP-binding enzyme K00666 - - 4.724e-234 742.0
HKD2_k127_7681415_10 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000005992 141.0
HKD2_k127_7681415_11 Transposase - - - 0.000000000000007715 87.0
HKD2_k127_7681415_12 - - - - 0.00000000000006424 77.0
HKD2_k127_7681415_13 - - - - 0.0000000004722 64.0
HKD2_k127_7681415_14 PFAM transposase IS4 family protein - - - 0.00008879 48.0
HKD2_k127_7681415_2 MMPL family K06994 - - 6.241e-200 649.0
HKD2_k127_7681415_3 AAA ATPase, central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 622.0
HKD2_k127_7681415_4 Histidyl-tRNA synthetase K01892 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 576.0
HKD2_k127_7681415_5 Transposase K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007405 515.0
HKD2_k127_7681415_6 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 314.0
HKD2_k127_7681415_7 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 293.0
HKD2_k127_7681415_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000004491 203.0
HKD2_k127_7681415_9 Bacterial protein of unknown function (DUF948) - - - 0.0000000000000000000000000000000000009892 141.0
HKD2_k127_7684029_0 TIGRFAM Pyrimidine-nucleoside phosphorylase K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 505.0
HKD2_k127_7684029_1 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000001022 183.0
HKD2_k127_7684029_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000004335 127.0
HKD2_k127_7691926_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 3.5e-222 702.0
HKD2_k127_7691926_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 1.971e-205 643.0
HKD2_k127_7691926_2 PFAM peptidase M50 K11749 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 493.0
HKD2_k127_7691926_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 473.0
HKD2_k127_7691926_4 PFAM GCN5-related N-acetyltransferase K06976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 447.0
HKD2_k127_7691926_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 424.0
HKD2_k127_7691926_6 Poly(3-hydroxybutyrate) depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004919 284.0
HKD2_k127_7691926_7 phosphatase activity K07025,K20866 - 3.1.3.10 0.00000000000000000000000000000000000000000000000000000000000000000002217 249.0
HKD2_k127_7691926_8 Domain of unknown function (DUF4439) - - - 0.000000000000000000000002064 111.0
HKD2_k127_7691926_9 - - - - 0.0001075 47.0
HKD2_k127_7692453_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 509.0
HKD2_k127_7692453_1 Transcriptional regulator sugar kinase K00845,K00886 - 2.7.1.2,2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 318.0
HKD2_k127_7692453_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor - - - 0.000000000000000000000000000000000000000000001737 188.0
HKD2_k127_7692453_3 molybdenum cofactor guanylyltransferase activity - - - 0.00000000000000124 88.0
HKD2_k127_7692453_4 TRANSCRIPTIONal - - - 0.0000000000002439 77.0
HKD2_k127_7700783_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009566 238.0
HKD2_k127_7700783_1 Methyltransferase domain - - - 0.0000000000000000001179 94.0
HKD2_k127_7700783_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000003218 87.0
HKD2_k127_7700783_3 Methyltransferase domain - - - 0.00000000000135 75.0
HKD2_k127_7700783_4 PFAM thioesterase superfamily - - - 0.00000004477 57.0
HKD2_k127_7700783_5 toxic component of a - - - 0.00001934 48.0
HKD2_k127_7722226_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 5.788e-233 731.0
HKD2_k127_7722226_1 Belongs to the GARS family K01945,K11788 GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000381 241.0
HKD2_k127_7722226_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000008805 210.0
HKD2_k127_7722226_3 SAICAR synthetase K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.000009229 49.0
HKD2_k127_7729302_0 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 1.206e-210 661.0
HKD2_k127_7729302_1 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000000000000000839 189.0
HKD2_k127_7729302_2 - - - - 0.00000000000000000003745 98.0
HKD2_k127_7729302_3 hydrolase of the alpha beta K07018 - - 0.000000124 59.0
HKD2_k127_7742354_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01962,K01963 - 2.1.3.15,6.4.1.2 6.936e-248 780.0
HKD2_k127_7742354_1 CHAT domain - - - 1.894e-230 756.0
HKD2_k127_7742354_10 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - 0.00000000000000000000000000000000000000000000000000000008773 204.0
HKD2_k127_7742354_11 SnoaL-like domain K14626 - - 0.00000000000000000000000000000000000000000000000001323 192.0
HKD2_k127_7742354_12 flavin reductase K14631 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0042602,GO:0055114 - 0.000000000000000000000000000000000000000000000002284 182.0
HKD2_k127_7742354_13 Biotin-requiring enzyme K02160 - - 0.0000000000000000000000000000001709 140.0
HKD2_k127_7742354_14 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000001641 119.0
HKD2_k127_7742354_15 Domain of unknown function (DUF4276) - - - 0.00000000000000000000001467 111.0
HKD2_k127_7742354_16 - - - - 0.0000000000000000000001224 114.0
HKD2_k127_7742354_17 DNA methylase - - - 0.00000000000003461 81.0
HKD2_k127_7742354_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 6.465e-203 661.0
HKD2_k127_7742354_3 NADPH quinone reductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 448.0
HKD2_k127_7742354_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K12420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 409.0
HKD2_k127_7742354_5 3-hydroxyacyl-CoA dehydrogenase K05556,K17735 - 1.1.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 398.0
HKD2_k127_7742354_6 Type I restriction-modification system methyltransferase subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 309.0
HKD2_k127_7742354_7 ADP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006909 245.0
HKD2_k127_7742354_8 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000006524 241.0
HKD2_k127_7742354_9 - K14627 - - 0.00000000000000000000000000000000000000000000000000000000001493 214.0
HKD2_k127_7743490_0 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 427.0
HKD2_k127_7743490_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 423.0
HKD2_k127_7743490_2 Beta-lactamase superfamily domain - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 377.0
HKD2_k127_7743490_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 376.0
HKD2_k127_7743490_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000008148 262.0
HKD2_k127_7743490_5 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000001608 180.0
HKD2_k127_7830395_0 Type I restriction enzyme R protein N terminus (HSDR_N) K01153 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000003941 243.0
HKD2_k127_7830395_1 Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin K07064 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000006368 162.0
HKD2_k127_7830395_2 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000000000000002443 87.0
HKD2_k127_7854769_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 509.0
HKD2_k127_7854769_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 400.0
HKD2_k127_7854769_2 Protein of unknown function (DUF501) K09009 - - 0.0000000000000000000000000000000000000000000000000000000000000000002387 248.0
HKD2_k127_7854769_3 Septum formation initiator K13052 - - 0.0000000000000000000000002786 119.0
HKD2_k127_7854769_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000001016 66.0
HKD2_k127_7855934_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 348.0
HKD2_k127_7855934_2 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000004379 225.0
HKD2_k127_7855934_4 helicase - - - 0.00000000000000000000000000003768 124.0
HKD2_k127_7855934_5 Protein of unknown function (DUF3311) - - - 0.0000000000000000000001078 102.0
HKD2_k127_7855934_6 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000008583 78.0
HKD2_k127_7855934_8 required for the transposition of insertion element IS2404 - - - 0.0007674 51.0
HKD2_k127_7856095_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 2.095e-244 796.0
HKD2_k127_7856095_1 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 539.0
HKD2_k127_7856095_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 474.0
HKD2_k127_7856095_3 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 381.0
HKD2_k127_7856095_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006539 240.0
HKD2_k127_7856095_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000001139 222.0
HKD2_k127_7856095_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000001362 183.0
HKD2_k127_7856095_7 - - - - 0.000000000000000006558 88.0
HKD2_k127_7856095_8 - - - - 0.00000000000000003565 90.0
HKD2_k127_7869015_0 Fructose transport system kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004856 263.0
HKD2_k127_7869015_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 0.00000000000000000000000000000000000002721 143.0
HKD2_k127_7913773_0 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000168 256.0
HKD2_k127_7913773_1 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000000000000000000000001697 212.0
HKD2_k127_7913773_2 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.000000000000000000000000000000000000000000000000001849 190.0
HKD2_k127_7913773_3 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000005688 183.0
HKD2_k127_7913773_4 competence protein - - - 0.0000000001089 66.0
HKD2_k127_7946808_0 PFAM Inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 353.0
HKD2_k127_7946808_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 314.0
HKD2_k127_7946808_2 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000006389 226.0
HKD2_k127_7946808_3 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000212 51.0
HKD2_k127_7949776_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 319.0
HKD2_k127_7949776_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000008598 244.0
HKD2_k127_7949776_2 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000006069 206.0
HKD2_k127_7949776_3 Protein of unknown function (DUF3710) - - - 0.0000000000000000000000000000000000000000000000000001774 197.0
HKD2_k127_7949776_4 Protein of unknown function (DUF4235) - - - 0.0000000000000000000000000000236 120.0
HKD2_k127_7949776_5 hydrolase activity, acting on ester bonds - - - 0.000000000001989 80.0
HKD2_k127_7949776_6 Protein of unknown function (DUF3093) - - - 0.00000000002629 70.0
HKD2_k127_7955120_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.8 0.0 1208.0
HKD2_k127_7955120_1 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 606.0
HKD2_k127_7955120_2 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 415.0
HKD2_k127_7955120_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 379.0
HKD2_k127_7955120_4 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000002076 239.0
HKD2_k127_7955120_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 0.000000000000000000000000000000000000000000000000000825 194.0
HKD2_k127_7955120_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000000000000003141 170.0
HKD2_k127_7956761_0 SMART Metal-dependent phosphohydrolase, HD region K00970,K00974 - 2.7.7.19,2.7.7.72 1.79e-238 745.0
HKD2_k127_7956761_1 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 1.117e-226 721.0
HKD2_k127_7956761_10 AP endonuclease family 2 K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 366.0
HKD2_k127_7956761_11 transcriptional regulator PadR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 304.0
HKD2_k127_7956761_12 Two component transcriptional regulator, LuxR family K07693 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 299.0
HKD2_k127_7956761_13 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009097 304.0
HKD2_k127_7956761_14 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005381 279.0
HKD2_k127_7956761_15 PFAM single-strand binding protein Primosomal replication protein n K03111 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004531 261.0
HKD2_k127_7956761_16 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001777 257.0
HKD2_k127_7956761_17 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002139 247.0
HKD2_k127_7956761_18 Family of unknown function (DUF5318) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002084 235.0
HKD2_k127_7956761_19 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000001259 243.0
HKD2_k127_7956761_2 Glycosyltransferase family 87 - - - 9.016e-203 676.0
HKD2_k127_7956761_20 pfam nlp p60 - - - 0.0000000000000000000000000000000000000000000000000000000000000009255 235.0
HKD2_k127_7956761_21 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000004121 205.0
HKD2_k127_7956761_22 - - - - 0.00000000000000000000000000000000000000000000001059 175.0
HKD2_k127_7956761_23 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000000000000000000000002993 169.0
HKD2_k127_7956761_24 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000008037 171.0
HKD2_k127_7956761_25 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001374 147.0
HKD2_k127_7956761_26 Glucitol operon activator - - - 0.0000000000000000000000000000000000001428 145.0
HKD2_k127_7956761_27 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000002695 147.0
HKD2_k127_7956761_28 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000001381 149.0
HKD2_k127_7956761_29 integral membrane protein - - - 0.000000000000000000000000000000004021 134.0
HKD2_k127_7956761_3 PFAM Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 1.179e-202 659.0
HKD2_k127_7956761_30 Domain of unknown function (DUF3817) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000003428 130.0
HKD2_k127_7956761_31 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000003549 147.0
HKD2_k127_7956761_32 integral membrane protein - - - 0.00000000000000000000000000002775 123.0
HKD2_k127_7956761_33 short-chain alcohol - - - 0.0000000000000000000000002098 114.0
HKD2_k127_7956761_34 Pfam:DUF385 - - - 0.000000000000000000000001302 111.0
HKD2_k127_7956761_35 Aminoacyl-tRNA editing domain - - - 0.0000000000000000008186 102.0
HKD2_k127_7956761_36 phosphatase activity K07025 - - 0.000000000004853 74.0
HKD2_k127_7956761_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 2.783e-202 683.0
HKD2_k127_7956761_5 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 436.0
HKD2_k127_7956761_6 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 400.0
HKD2_k127_7956761_7 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 423.0
HKD2_k127_7956761_8 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 381.0
HKD2_k127_7956761_9 signal transduction histidine kinase K07778 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 370.0
HKD2_k127_796774_0 succinate dehydrogenase K00239,K00278 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4,1.4.3.16 7.544e-197 632.0
HKD2_k127_796774_1 S-adenosyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002866 243.0
HKD2_k127_796774_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000001732 203.0
HKD2_k127_796774_3 serine threonine protein kinase - - - 0.0000003058 61.0
HKD2_k127_7972622_0 geranylgeranyl reductase K21401 - 1.3.99.38 8.524e-208 657.0
HKD2_k127_7972622_1 PFAM Adenosine AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 522.0
HKD2_k127_7972622_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 361.0
HKD2_k127_7972622_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 338.0
HKD2_k127_7972622_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 345.0
HKD2_k127_7972622_5 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003308 271.0
HKD2_k127_7972622_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000001592 211.0
HKD2_k127_8006222_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 534.0
HKD2_k127_8006222_1 Two component transcriptional regulator, LuxR family K07695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 329.0
HKD2_k127_8006222_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001838 257.0
HKD2_k127_8006222_3 Metal-sensitive transcriptional repressor - - - 0.00000000000000000000000000000008238 128.0
HKD2_k127_8006222_4 Universal stress protein family - - - 0.000000000000000000000000007624 118.0
HKD2_k127_8006222_5 PAP2 superfamily - - - 0.0000000000004431 70.0
HKD2_k127_8006819_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 582.0
HKD2_k127_8006819_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K21572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 372.0
HKD2_k127_8006819_2 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001402 284.0
HKD2_k127_8006819_3 spheroidene monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000996 272.0
HKD2_k127_8007207_0 DNA polymerase III, epsilon subunit K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 8.042e-234 740.0
HKD2_k127_8007207_1 PFAM Rieske 2Fe-2S K03890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 501.0
HKD2_k127_8007207_10 response regulator - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000009978 179.0
HKD2_k127_8007207_11 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000001321 133.0
HKD2_k127_8007207_12 Belongs to the group II decarboxylase family K01580 GO:0005575,GO:0005911,GO:0009506,GO:0030054,GO:0055044 4.1.1.15 0.00000000000006155 73.0
HKD2_k127_8007207_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 467.0
HKD2_k127_8007207_3 Cytochrome c oxidase caa3-type, assembly factor CtaG-related K02351,K07245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 439.0
HKD2_k127_8007207_4 PFAM cytochrome c oxidase, subunit III K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 361.0
HKD2_k127_8007207_5 cytochrome C K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 338.0
HKD2_k127_8007207_6 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004012 276.0
HKD2_k127_8007207_7 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002787 258.0
HKD2_k127_8007207_8 belongs to the Fur family K03711,K09825 - - 0.00000000000000000000000000000000000000000000000000004573 189.0
HKD2_k127_8007207_9 Cytochrome b K03891 - - 0.000000000000000000000000000000000000000000000000001449 192.0
HKD2_k127_8036910_0 Vitamin B12 dependent methionine synthase activation K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1217.0
HKD2_k127_8036910_1 DEAD DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0 1196.0
HKD2_k127_8036910_10 WYL domain K13572,K13573 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 416.0
HKD2_k127_8036910_11 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019774,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 409.0
HKD2_k127_8036910_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 406.0
HKD2_k127_8036910_13 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 401.0
HKD2_k127_8036910_14 WYL domain K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 414.0
HKD2_k127_8036910_15 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 359.0
HKD2_k127_8036910_16 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 302.0
HKD2_k127_8036910_17 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001994 252.0
HKD2_k127_8036910_18 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000000008432 166.0
HKD2_k127_8036910_19 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000000000000004263 152.0
HKD2_k127_8036910_2 ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 0.0 1080.0
HKD2_k127_8036910_20 subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000001529 149.0
HKD2_k127_8036910_21 - - - - 0.000000000000000000000000000000000002331 156.0
HKD2_k127_8036910_22 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000005759 134.0
HKD2_k127_8036910_23 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000000000000000000000003708 125.0
HKD2_k127_8036910_24 - - - - 0.0000000000000000000000000002355 117.0
HKD2_k127_8036910_25 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation K13570 GO:0003674,GO:0005488,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0031386,GO:0032446,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044877,GO:0051603,GO:0070490,GO:0070628,GO:0070647,GO:0071704,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000002111 108.0
HKD2_k127_8036910_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0008150,GO:0040007 - 0.00000000000000000108 89.0
HKD2_k127_8036910_27 haloacid dehalogenase-like hydrolase - - - 0.0000000000003103 79.0
HKD2_k127_8036910_29 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000001603 58.0
HKD2_k127_8036910_3 FtsX-like permease family K02004 - - 6.947e-306 959.0
HKD2_k127_8036910_30 Ribbon-helix-helix protein, copG family - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.00001018 53.0
HKD2_k127_8036910_4 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 3.261e-295 912.0
HKD2_k127_8036910_5 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 1.496e-281 867.0
HKD2_k127_8036910_6 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 524.0
HKD2_k127_8036910_7 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 445.0
HKD2_k127_8036910_8 PD-(D/E)XK nuclease superfamily K07465 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 440.0
HKD2_k127_8036910_9 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 463.0
HKD2_k127_8046412_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.482e-279 867.0
HKD2_k127_8046412_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 552.0
HKD2_k127_8046412_2 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 338.0
HKD2_k127_8046412_3 Membrane-bound lytic murein transglycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000001154 243.0
HKD2_k127_8046412_4 protein with CBS domains - - - 0.00000000000000000000000000000000000000000000000003758 183.0
HKD2_k127_8046412_6 - - - - 0.0005849 51.0
HKD2_k127_8090827_0 flavoprotein involved in K transport - - - 3.3e-249 787.0
HKD2_k127_8090827_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 323.0
HKD2_k127_8090827_2 - - - - 0.000000000000000000000000000000000000000000000000000000000009101 216.0
HKD2_k127_8090827_3 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000002845 189.0
HKD2_k127_8090827_4 required for the transposition of insertion element IS2404 - - - 0.000001582 49.0
HKD2_k127_8091698_0 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 456.0
HKD2_k127_8091698_1 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 450.0
HKD2_k127_8091698_2 Amidohydrolase family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 427.0
HKD2_k127_8091698_3 CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 397.0
HKD2_k127_8091698_4 - - - - 0.000000000000000005493 87.0
HKD2_k127_8126831_0 Helix-turn-helix domain of transposase family ISL3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 337.0
HKD2_k127_8126831_1 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002259 250.0
HKD2_k127_8126831_2 Evidence 2b Function of strongly homologous gene - - - 0.00000000002257 68.0
HKD2_k127_8131346_0 type III restriction protein res subunit K10843 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 567.0
HKD2_k127_8131346_1 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000001831 196.0
HKD2_k127_8131346_2 Nucleotidyltransferase domain - - - 0.000000000000000000000000000000000000000000000001492 183.0
HKD2_k127_8131346_3 type III restriction protein res subunit K10843 - 3.6.4.12 0.0000000000000000006596 87.0
HKD2_k127_8131346_4 - - - - 0.000000009802 61.0
HKD2_k127_8133345_0 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 368.0
HKD2_k127_8133345_1 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007538 287.0
HKD2_k127_8133345_2 Patatin-like phospholipase - - - 0.000000000000000000000000000001593 141.0
HKD2_k127_8133345_3 response regulator - - - 0.00000000000000000000000000003653 122.0
HKD2_k127_8133345_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.0008668 42.0
HKD2_k127_8137799_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 2.493e-226 711.0
HKD2_k127_8137799_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 463.0
HKD2_k127_8137799_10 Winged helix-turn helix - - - 0.0002496 43.0
HKD2_k127_8137799_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 322.0
HKD2_k127_8137799_3 Protein of unknown function (DUF3141) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000024 287.0
HKD2_k127_8137799_4 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004848 280.0
HKD2_k127_8137799_5 Protein of unknown function (DUF3141) - - - 0.0000000000000000000000000000000000003364 142.0
HKD2_k127_8137799_6 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000002135 124.0
HKD2_k127_8137799_7 Transcriptional regulator - - - 0.0000000000000000000003249 104.0
HKD2_k127_8137799_8 positive regulation of growth - - - 0.0000000000000000000003465 104.0
HKD2_k127_8137799_9 PFAM transposase IS4 family protein - - - 0.0000000000000000387 84.0
HKD2_k127_8154652_0 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000000000000001396 168.0
HKD2_k127_8154652_1 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000367 138.0
HKD2_k127_8154652_2 conserved protein, contains double-stranded beta-helix domain - - - 0.0000000000000000000000002302 111.0
HKD2_k127_8174638_0 Alcohol dehydrogenase GroES-like domain - - - 1.512e-210 659.0
HKD2_k127_8174638_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 510.0
HKD2_k127_8174638_10 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000009661 234.0
HKD2_k127_8174638_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000003651 183.0
HKD2_k127_8174638_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000001379 154.0
HKD2_k127_8174638_13 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000008783 125.0
HKD2_k127_8174638_14 - - - - 0.000000000000000001305 94.0
HKD2_k127_8174638_15 regulatory protein - - - 0.00000000000000005537 81.0
HKD2_k127_8174638_16 DNA excision - - - 0.0000000000000003142 79.0
HKD2_k127_8174638_18 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00007327 51.0
HKD2_k127_8174638_2 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 500.0
HKD2_k127_8174638_20 Phage integrase family - - - 0.0006046 45.0
HKD2_k127_8174638_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 480.0
HKD2_k127_8174638_4 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 415.0
HKD2_k127_8174638_5 ATPases associated with a variety of cellular activities K02006,K16784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 386.0
HKD2_k127_8174638_6 transmembrane transporter activity K02007,K02008 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 372.0
HKD2_k127_8174638_7 peptide deformylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 324.0
HKD2_k127_8174638_8 PFAM Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 317.0
HKD2_k127_8174638_9 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 301.0
HKD2_k127_8185715_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 6.921e-229 716.0
HKD2_k127_8185715_1 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 2.14e-201 637.0
HKD2_k127_8185715_2 protein phosphatase 2C domain protein K11928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 306.0
HKD2_k127_8187335_0 Belongs to the helicase family. UvrD subfamily K03657 - 3.6.4.12 0.0 1338.0
HKD2_k127_8187335_1 Belongs to the helicase family. UvrD subfamily - - - 7.787e-268 862.0
HKD2_k127_8187335_10 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 304.0
HKD2_k127_8187335_11 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006312 272.0
HKD2_k127_8187335_12 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001451 286.0
HKD2_k127_8187335_13 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000002153 189.0
HKD2_k127_8187335_14 PFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding - - - 0.00000000000000000000000000000000000000000001042 181.0
HKD2_k127_8187335_15 - - - - 0.0000000000000000000000000003385 121.0
HKD2_k127_8187335_16 Protein of unknown function (DUF3107) - - - 0.00000000000000000000000005958 108.0
HKD2_k127_8187335_17 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000004477 78.0
HKD2_k127_8187335_19 PFAM PspC domain protein - - - 0.00000000001807 69.0
HKD2_k127_8187335_2 PFAM UBA THIF-type NAD FAD binding K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0019344,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.80,2.8.1.11 1.324e-225 712.0
HKD2_k127_8187335_3 PFAM Peptidase M16 - - - 2.228e-208 689.0
HKD2_k127_8187335_4 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 2.531e-207 675.0
HKD2_k127_8187335_5 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 412.0
HKD2_k127_8187335_6 transcriptional regulator, PucR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 388.0
HKD2_k127_8187335_7 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 387.0
HKD2_k127_8187335_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 348.0
HKD2_k127_8187335_9 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 297.0
HKD2_k127_8194686_0 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 509.0
HKD2_k127_8194686_1 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 430.0
HKD2_k127_8194686_2 - - - - 0.00000000000000000003194 96.0
HKD2_k127_8214839_0 Diguanylate cyclase - - - 3.045e-285 897.0
HKD2_k127_8214839_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 538.0
HKD2_k127_8214839_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000008239 181.0
HKD2_k127_8214839_11 Transcriptional regulator - - - 0.000000000000000000000000001559 113.0
HKD2_k127_8214839_12 Regulatory protein, FmdB family - - - 0.00000000000000000000000003942 109.0
HKD2_k127_8214839_13 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0000000000000000000001049 113.0
HKD2_k127_8214839_2 Sulfotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 458.0
HKD2_k127_8214839_3 dimethylargininase activity K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 361.0
HKD2_k127_8214839_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 304.0
HKD2_k127_8214839_5 Esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002012 290.0
HKD2_k127_8214839_6 PFAM transcriptional regulator PadR family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009135 252.0
HKD2_k127_8214839_7 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000002594 230.0
HKD2_k127_8214839_8 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000002711 223.0
HKD2_k127_8214839_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000003416 201.0
HKD2_k127_8268298_0 Uroporphyrinogen III synthase HEM4 K01719,K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 619.0
HKD2_k127_8268298_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 499.0
HKD2_k127_8268298_2 Domain of unknown function (DUF4397) - - - 0.000000000000000000000000000000000000000000000000000000006661 217.0
HKD2_k127_8268298_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000001045 192.0
HKD2_k127_8268298_4 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000002055 176.0
HKD2_k127_8268298_5 Anti-sigma-K factor rskA - - - 0.000000000000000000007749 103.0
HKD2_k127_8268298_6 - - - - 0.000000085 63.0
HKD2_k127_8282437_0 Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA - GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040007,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001683 284.0
HKD2_k127_8303209_0 PFAM RNA binding S1 domain protein K02945 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 2.243e-276 864.0
HKD2_k127_8303209_1 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 424.0
HKD2_k127_8303209_2 PFAM methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 366.0
HKD2_k127_8303209_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002093 281.0
HKD2_k127_8303209_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000007797 246.0
HKD2_k127_8303209_5 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 0.00000000000000000000000000000000000000000000000000000000000001619 218.0
HKD2_k127_8326554_0 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 540.0
HKD2_k127_8326554_1 signal transduction histidine kinase K07653 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 479.0
HKD2_k127_8326554_2 mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 435.0
HKD2_k127_8326554_3 Two component transcriptional regulator, winged helix family K07669,K07672 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 373.0
HKD2_k127_8326554_4 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 320.0
HKD2_k127_8326554_5 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 291.0
HKD2_k127_8326554_6 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000001353 132.0
HKD2_k127_8326554_7 - - - - 0.00000000003355 74.0
HKD2_k127_8367443_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 2.5.1.120 2.853e-218 680.0
HKD2_k127_8367443_1 N-6 DNA Methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 429.0
HKD2_k127_8367443_2 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 309.0
HKD2_k127_8367443_3 AsnC family transcriptional regulator K03719 - - 0.0000000000000000000000000000000000000000000000000000007315 196.0
HKD2_k127_8367443_4 Acyltransferase - - - 0.00000000000000000000000000000000000000000003432 164.0
HKD2_k127_8377070_0 Pyridine nucleotide-disulphide oxidoreductase - - - 1.012e-213 672.0
HKD2_k127_8377070_1 Fructose-bisphosphate aldolase, class II K01624 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 573.0
HKD2_k127_8385662_0 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0 1361.0
HKD2_k127_8385662_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 379.0
HKD2_k127_8385662_2 PFAM Cyclic nucleotide-binding K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 378.0
HKD2_k127_8385662_3 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 351.0
HKD2_k127_8385662_4 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 305.0
HKD2_k127_8385662_5 NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002493 286.0
HKD2_k127_8385662_6 Colicin V production protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000002812 224.0
HKD2_k127_8385662_7 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000006018 200.0
HKD2_k127_8385662_8 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000001331 125.0
HKD2_k127_8385662_9 - - - - 0.000000000000000000000001079 103.0
HKD2_k127_8410842_0 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 295.0
HKD2_k127_8410842_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000001851 195.0
HKD2_k127_8410842_2 Nudix hydrolase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000527 160.0
HKD2_k127_8410842_3 Elongation factor G C-terminus K06207 - - 0.000000000000000000000000000175 125.0
HKD2_k127_8410842_4 PIN domain K18828 - - 0.000000000000000000000000008518 117.0
HKD2_k127_8410842_5 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000006051 95.0
HKD2_k127_8410842_6 Protein of unknown function (DUF2795) - - - 0.000000000000000008443 84.0
HKD2_k127_8410842_7 - - - - 0.000000003662 60.0
HKD2_k127_8440548_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0008150,GO:0040007 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 289.0
HKD2_k127_8440548_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000001115 248.0
HKD2_k127_8440548_2 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001748 214.0
HKD2_k127_8440548_3 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000003205 148.0
HKD2_k127_8440548_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000001236 124.0
HKD2_k127_8481385_0 Evidence 4 Homologs of previously reported genes of - - - 1.301e-270 839.0
HKD2_k127_8481385_1 - - - - 6.969e-265 834.0
HKD2_k127_8481385_2 Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine K01919 GO:0003674,GO:0003824,GO:0004357,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0044464,GO:0071944 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 468.0
HKD2_k127_8481385_3 PFAM NERD domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 338.0
HKD2_k127_8481385_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 325.0
HKD2_k127_8507927_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 5.219e-222 698.0
HKD2_k127_8507927_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 516.0
HKD2_k127_8507927_10 CAAX amino terminal protease family K07052 - - 0.0000008541 61.0
HKD2_k127_8507927_2 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 475.0
HKD2_k127_8507927_3 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 355.0
HKD2_k127_8507927_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006226 249.0
HKD2_k127_8507927_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000009653 231.0
HKD2_k127_8507927_6 - - - - 0.00000000000000000000000000000003007 134.0
HKD2_k127_8507927_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000000000000000000000004894 111.0
HKD2_k127_8507927_8 Bacterial antitoxin of type II TA system, VapB - GO:0006417,GO:0008150,GO:0009605,GO:0009607,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0040008,GO:0043207,GO:0044403,GO:0044419,GO:0045727,GO:0045927,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:2000112 - 0.00000000000000296 90.0
HKD2_k127_8507927_9 cytochrome oxidase assembly K02259 - - 0.00000000000005152 77.0
HKD2_k127_8558930_0 Carboxyl transferase domain - - - 6.554e-258 804.0
HKD2_k127_8558930_1 acyl-CoA dehydrogenase K00248,K11410 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 587.0
HKD2_k127_8558930_2 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 437.0
HKD2_k127_8558930_3 PFAM GtrA family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005201 231.0
HKD2_k127_8558930_4 PIN domain - - - 0.000000000000000000000119 106.0
HKD2_k127_8591346_0 Belongs to the peptidase S8 family - - - 1.811e-197 631.0
HKD2_k127_8591346_1 FMN-dependent dehydrogenase K00467 - 1.13.12.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 475.0
HKD2_k127_8591346_10 chlorophyll binding - - - 0.0000000000000000005312 95.0
HKD2_k127_8591346_12 Dodecin K09165 - - 0.0000000002747 61.0
HKD2_k127_8591346_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 458.0
HKD2_k127_8591346_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 445.0
HKD2_k127_8591346_4 Short-chain dehydrogenase reductase SDR K00059,K11610 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0018454,GO:0019752,GO:0030497,GO:0032787,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046459,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070402,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 328.0
HKD2_k127_8591346_5 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003113 280.0
HKD2_k127_8591346_6 ATP-NAD kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000003955 265.0
HKD2_k127_8591346_7 HIT domain K02503 - - 0.0000000000000000000000000000000322 138.0
HKD2_k127_8591346_8 chlorophyll binding - - - 0.000000000000000000000001351 109.0
HKD2_k127_8603036_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 436.0
HKD2_k127_8603036_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 307.0
HKD2_k127_8603036_2 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001016 229.0
HKD2_k127_8603036_3 PIN domain - - - 0.0000000000000000000000000000000000000000003819 167.0
HKD2_k127_8603036_5 - K21495 - - 0.0000001614 58.0
HKD2_k127_8617849_0 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 622.0
HKD2_k127_8617849_1 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 353.0
HKD2_k127_8617849_2 PIN domain - - - 0.0000007887 56.0
HKD2_k127_8617849_3 TOBE domain - - - 0.0002477 48.0
HKD2_k127_8658220_0 light absorption K06893 - - 0.000000000000000000000000000000000000000000000005667 194.0
HKD2_k127_8658220_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000001026 168.0
HKD2_k127_8669948_0 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 355.0
HKD2_k127_8669948_1 TIGRFAM malto-oligosyltrehalose trehalohydrolase K01236 - 3.2.1.141 0.000000000000000000000000000000000000000000000000000000005363 201.0
HKD2_k127_8682021_0 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 381.0
HKD2_k127_8682021_1 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000002143 183.0
HKD2_k127_8682021_4 required for the transposition of insertion element IS2404 - - - 0.000005682 48.0
HKD2_k127_8704354_0 Nitrate reductase beta subunit K00371 - 1.7.5.1 5.221e-294 926.0
HKD2_k127_8704354_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 8.343e-225 701.0
HKD2_k127_8704354_2 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 512.0
HKD2_k127_8704354_3 TIGRFAM respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 375.0
HKD2_k127_8704354_4 Nitrate reductase delta subunit K00373 - - 0.00000000000000000000000000000000000000000000000000000000000694 234.0
HKD2_k127_8704354_5 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.00000000000000000000000000000000000009367 150.0
HKD2_k127_8718327_0 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 307.0
HKD2_k127_8718327_1 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000002012 179.0
HKD2_k127_8718327_2 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.000000000000000000000000000000000000000002321 162.0
HKD2_k127_8718327_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000008418 136.0
HKD2_k127_8718327_4 multisubunit Na H antiporter MnhE subunit K05569 - - 0.000000000000000001233 98.0
HKD2_k127_8718327_5 monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.000000000001039 75.0
HKD2_k127_8718327_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000003538 68.0
HKD2_k127_8718327_7 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.00000000072 70.0
HKD2_k127_8719744_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.4.4.2 0.0 1428.0
HKD2_k127_8719744_1 Glutamine amidotransferase domain K00820 - 2.6.1.16 1.593e-279 899.0
HKD2_k127_8719744_10 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002059 263.0
HKD2_k127_8719744_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006883 238.0
HKD2_k127_8719744_12 transcriptional regulator K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000002248 239.0
HKD2_k127_8719744_13 - - - - 0.0000000000000000000000001056 109.0
HKD2_k127_8719744_14 Clp amino terminal domain, pathogenicity island component - - - 0.000000000000000000000001483 114.0
HKD2_k127_8719744_15 - - - - 0.0000000000000000000003779 100.0
HKD2_k127_8719744_16 - - - - 0.0000000000000000000004833 97.0
HKD2_k127_8719744_17 Glycosyl transferase family group 2 - - - 0.0000003963 57.0
HKD2_k127_8719744_19 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0002146 48.0
HKD2_k127_8719744_2 Amino acid permease - - - 3.385e-261 820.0
HKD2_k127_8719744_3 AMP-binding enzyme C-terminal domain K00666 - - 8.779e-227 715.0
HKD2_k127_8719744_4 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 477.0
HKD2_k127_8719744_5 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 412.0
HKD2_k127_8719744_6 stress protein K05795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 340.0
HKD2_k127_8719744_7 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 304.0
HKD2_k127_8719744_8 Phage shock protein A K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 292.0
HKD2_k127_8719744_9 Glyco_18 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000527 288.0
HKD2_k127_8802616_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 568.0
HKD2_k127_8802616_1 Belongs to the SEDS family K02563,K03588 GO:0008150,GO:0040007 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 462.0
HKD2_k127_8815759_0 PFAM Transketolase central region K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 545.0
HKD2_k127_8815759_1 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 567.0
HKD2_k127_8815759_2 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 423.0
HKD2_k127_8815759_3 PFAM NLP P60 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 376.0
HKD2_k127_8815759_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 314.0
HKD2_k127_8815759_5 SERine Proteinase INhibitors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 304.0
HKD2_k127_8815759_6 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000002679 224.0
HKD2_k127_8815759_7 - - - - 0.000000000000000000000000000000000000000000000002501 180.0
HKD2_k127_8815759_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000002221 169.0
HKD2_k127_8827745_0 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 329.0
HKD2_k127_8827745_1 transcriptional regulator, TetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 288.0
HKD2_k127_8827745_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K01768,K07315,K11928 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009165,GO:0009166,GO:0009187,GO:0009190,GO:0009214,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0052621,GO:0055086,GO:0071111,GO:0071704,GO:0071944,GO:0090407,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000379 156.0
HKD2_k127_8827745_3 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000003241 101.0
HKD2_k127_8827745_4 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000005974 62.0
HKD2_k127_8827745_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00002798 48.0
HKD2_k127_8834430_0 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 488.0
HKD2_k127_8834430_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 357.0
HKD2_k127_8834430_2 Protein of unknown function (DUF1416) - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000004765 164.0
HKD2_k127_8834430_3 spore germination K03605 - - 0.00000000000000000000000000000000000002422 153.0
HKD2_k127_8834430_4 Staphylococcal nuclease homologues K01174,K01286 - 3.1.31.1,3.4.16.4 0.000000000000000000000001816 115.0
HKD2_k127_8834430_5 nickel cation binding K04651 - - 0.0000000000000000000004154 104.0
HKD2_k127_8834430_6 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000008443 84.0
HKD2_k127_8899409_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0 1076.0
HKD2_k127_8899409_1 ComEC Rec2-related protein K02238 - - 2.459e-203 656.0
HKD2_k127_8899409_2 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 419.0
HKD2_k127_8899409_3 PFAM catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 344.0
HKD2_k127_8899409_4 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 299.0
HKD2_k127_8899409_5 helix-hairpin-helix K02237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000128 256.0
HKD2_k127_8899409_6 TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000001575 178.0
HKD2_k127_8899409_7 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000001369 123.0
HKD2_k127_8899409_8 dextransucrase activity K03975,K07126,K13963,K21012 - - 0.00000001793 66.0
HKD2_k127_8944806_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 497.0
HKD2_k127_8944806_1 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000008518 211.0
HKD2_k127_8959451_0 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 538.0
HKD2_k127_8959451_1 PFAM CoA-transferase family III K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 374.0
HKD2_k127_8959451_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000002156 117.0
HKD2_k127_8984639_0 Acyl-CoA dehydrogenase, middle domain - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 5.654e-273 852.0
HKD2_k127_8984639_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 550.0
HKD2_k127_8984639_2 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000001703 218.0
HKD2_k127_8984639_3 antisigma factor binding K04749,K05946,K06378 - 2.4.1.187 0.000001923 54.0
HKD2_k127_8988179_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 559.0
HKD2_k127_8988179_1 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003181 245.0
HKD2_k127_8988179_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000004797 120.0
HKD2_k127_8988179_3 Protein of unknown function (DUF1275) - - - 0.0000000000000000000006752 105.0
HKD2_k127_8988179_4 Universal stress protein family - - - 0.00000000000000000000971 108.0
HKD2_k127_8988179_5 amino acid transport - - - 0.0000000000000000002801 98.0
HKD2_k127_8988179_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000007435 82.0
HKD2_k127_8988179_7 FAD linked oxidases, C-terminal domain - - - 0.0000000351 61.0
HKD2_k127_8988179_8 - - - - 0.00000006601 63.0
HKD2_k127_8996246_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00278 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4,1.4.3.16 0.0 1014.0
HKD2_k127_8996246_1 Acyl-CoA synthetase (NDP forming) - - - 1.082e-243 785.0
HKD2_k127_8996246_10 EamA-like transporter family K11939 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001248 279.0
HKD2_k127_8996246_11 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000000003569 153.0
HKD2_k127_8996246_12 belongs to the nudix hydrolase family - - - 0.000000000000000000000000002126 120.0
HKD2_k127_8996246_13 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000001482 116.0
HKD2_k127_8996246_14 - - - - 0.000000000000000000007365 108.0
HKD2_k127_8996246_15 - - - - 0.0000000000004053 75.0
HKD2_k127_8996246_2 PFAM peptidase M24 K01262 - 3.4.11.9 1.765e-231 728.0
HKD2_k127_8996246_3 PFAM Histone deacetylase K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 586.0
HKD2_k127_8996246_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 439.0
HKD2_k127_8996246_5 Succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 437.0
HKD2_k127_8996246_6 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 376.0
HKD2_k127_8996246_7 PFAM ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 373.0
HKD2_k127_8996246_8 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 360.0
HKD2_k127_8996246_9 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 357.0
HKD2_k127_9033359_0 plastoquinol--plastocyanin reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 545.0
HKD2_k127_9033359_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K20435 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 506.0
HKD2_k127_9033359_10 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000000000000009251 136.0
HKD2_k127_9033359_11 - - - - 0.0000000000000000000000000000000001017 141.0
HKD2_k127_9033359_12 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.00000000000000000000000000000007809 136.0
HKD2_k127_9033359_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 266.0
HKD2_k127_9033359_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001042 262.0
HKD2_k127_9033359_4 Alcohol dehydrogenase, GroES domain protein K20434 - - 0.00000000000000000000000000000000000000000000000000000000006765 218.0
HKD2_k127_9033359_5 Glycosyltransferase family 20 K20436 - 2.5.1.135 0.000000000000000000000000000000000000000000000000000000001911 207.0
HKD2_k127_9033359_6 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.00000000000000000000000000000000000000000000000000000003629 202.0
HKD2_k127_9033359_7 N-acetylglucosamine kinase activity K18676 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931 2.7.1.8 0.00000000000000000000000000000000000000000000000000002227 213.0
HKD2_k127_9033359_8 PIN domain - - - 0.00000000000000000000000000000000000000000000000002556 184.0
HKD2_k127_9033359_9 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000004782 159.0
HKD2_k127_90508_0 GH3 auxin-responsive promoter - - - 4.169e-283 890.0
HKD2_k127_90508_1 Alanine-glyoxylate amino-transferase K16423 - 2.6.1.103 2.849e-211 671.0
HKD2_k127_90508_10 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001294 255.0
HKD2_k127_90508_11 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002134 246.0
HKD2_k127_90508_12 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000008474 241.0
HKD2_k127_90508_13 ThiJ PfpI - - - 0.000000000000000000000000000000000000000000000000000000000000000001349 239.0
HKD2_k127_90508_14 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000005315 168.0
HKD2_k127_90508_15 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.00000000000000000000000000000001132 138.0
HKD2_k127_90508_16 TIGRFAM daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.00000000000000000000000000000004439 126.0
HKD2_k127_90508_17 YCII-related domain K09780 - - 0.0000000000000000000000000000005106 132.0
HKD2_k127_90508_19 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000009311 87.0
HKD2_k127_90508_2 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 603.0
HKD2_k127_90508_20 required for the transposition of insertion element IS2404 - - - 0.0000000001234 66.0
HKD2_k127_90508_21 Transmembrane secretion effector - - - 0.0003061 48.0
HKD2_k127_90508_3 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 570.0
HKD2_k127_90508_4 carboxylic acid catabolic process K01856,K19802 - 5.1.1.20,5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 450.0
HKD2_k127_90508_5 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 441.0
HKD2_k127_90508_6 Pfam:Methyltransf_26 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 395.0
HKD2_k127_90508_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059,K07124,K21883 - 1.1.1.100,1.1.1.401 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 381.0
HKD2_k127_90508_8 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 368.0
HKD2_k127_90508_9 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001051 258.0
HKD2_k127_9066734_0 C-C_Bond_Lyase of the TIM-Barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 564.0
HKD2_k127_9066734_1 Phosphoribosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 467.0
HKD2_k127_9066734_2 PIN domain - - - 0.0000000000000000000000000000008289 123.0
HKD2_k127_9108666_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 610.0
HKD2_k127_9108666_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 500.0
HKD2_k127_9108666_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000001604 194.0
HKD2_k127_9108666_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000001099 146.0
HKD2_k127_9108666_4 - - - - 0.000000000000000000001584 102.0
HKD2_k127_9142549_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 584.0
HKD2_k127_9142549_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 391.0
HKD2_k127_9142549_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0005575,GO:0005576 - 0.00000000000000009618 87.0
HKD2_k127_9142549_3 toxin-antitoxin pair type II binding - - - 0.000000004758 67.0
HKD2_k127_9142549_4 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity K13991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464 - 0.00001723 55.0
HKD2_k127_9150646_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 425.0
HKD2_k127_9150646_1 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 321.0
HKD2_k127_9150646_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 301.0
HKD2_k127_9150646_3 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000001519 270.0
HKD2_k127_9150646_4 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000001324 218.0
HKD2_k127_9150646_5 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000001982 214.0
HKD2_k127_9150646_6 type II secretion system protein - - - 0.000000000000000000000000000000008364 140.0
HKD2_k127_9150646_7 methyltransferase activity K00587 - 2.1.1.100 0.0000000000000000000007009 98.0
HKD2_k127_9170860_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 427.0
HKD2_k127_9170860_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 372.0
HKD2_k127_9170860_2 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000001904 243.0
HKD2_k127_9170860_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.00000000000000000002594 106.0
HKD2_k127_9185398_0 PFAM Cys Met metabolism K01740 - 2.5.1.49 6.856e-252 781.0
HKD2_k127_9185398_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 622.0
HKD2_k127_9185398_10 transcriptional regulator - - - 0.00000000000000000000000009793 112.0
HKD2_k127_9185398_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 572.0
HKD2_k127_9185398_3 Glycosyl transferases group 1 K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 530.0
HKD2_k127_9185398_4 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 471.0
HKD2_k127_9185398_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000008477 216.0
HKD2_k127_9185398_6 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000003748 209.0
HKD2_k127_9185398_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000281 192.0
HKD2_k127_9185398_8 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000003862 176.0
HKD2_k127_9185398_9 Translation elongation factor K03833 - - 0.00000000000000000000000000006781 120.0
HKD2_k127_9189418_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 8.8e-265 838.0
HKD2_k127_9189418_1 - - - - 8.207e-214 698.0
HKD2_k127_9189418_10 Major facilitator superfamily - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000002753 89.0
HKD2_k127_9189418_11 Protein of unknown function (DUF3068) - - - 0.0000003487 63.0
HKD2_k127_9189418_2 type III restriction protein res subunit K10843 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 497.0
HKD2_k127_9189418_3 Major facilitator superfamily - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 446.0
HKD2_k127_9189418_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 411.0
HKD2_k127_9189418_5 PFAM ExsB family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 381.0
HKD2_k127_9189418_6 Protein of unknown function (DUF3027) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 375.0
HKD2_k127_9189418_7 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000000000000000000000000000000000000000198 222.0
HKD2_k127_9189418_8 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000000000000005243 184.0
HKD2_k127_9189418_9 Putative restriction endonuclease - - - 0.0000000000000000000000000000019 127.0
HKD2_k127_9200628_0 Histidine kinase K07636,K07654 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 476.0
HKD2_k127_9200628_1 Transcriptional regulatory protein, C terminal K07670 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 370.0
HKD2_k127_9200628_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000007995 239.0
HKD2_k127_9200628_3 pathogenesis - - - 0.00000000000000000000000000000000000000000000000000000000001215 226.0
HKD2_k127_9200628_4 phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000004599 174.0
HKD2_k127_9200628_5 Lipoprotein LpqB beta-propeller domain - - - 0.00000000000000000000000000000000000008644 165.0
HKD2_k127_9200628_6 Response regulator receiver K02479 - - 0.00000000000000000000000000004869 119.0
HKD2_k127_9205393_0 Clp domain protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 2.83e-265 820.0
HKD2_k127_9205393_1 helix-turn-helix- domain containing protein, AraC type K13529 - 3.2.2.21 2.439e-199 646.0
HKD2_k127_9205393_2 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP K07067 - 2.7.7.85 1.963e-194 612.0
HKD2_k127_9205393_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 607.0
HKD2_k127_9205393_4 helix-hairpin-helix motif K03575 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 402.0
HKD2_k127_9205393_5 Hypothetical methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000245 283.0
HKD2_k127_9205393_6 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007251 272.0
HKD2_k127_9205393_7 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000003309 190.0
HKD2_k127_9205393_8 Copper chaperone PCu(A)C - - - 0.00000000000000000000000000000003799 143.0
HKD2_k127_9227933_0 Glycoside hydrolase 15-related - - - 3.512e-224 702.0
HKD2_k127_9227933_1 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000001396 195.0
HKD2_k127_9228760_0 Isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.595e-206 652.0
HKD2_k127_9228760_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 613.0
HKD2_k127_9228760_10 TIGRFAM cell envelope-related function transcriptional attenuator - - - 0.000000000000000000000000000007762 129.0
HKD2_k127_9228760_11 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000166 127.0
HKD2_k127_9228760_12 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000009744 95.0
HKD2_k127_9228760_13 acyl-CoA dehydrogenase K00248,K11410 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.00000000000000001052 82.0
HKD2_k127_9228760_14 - - - - 0.00000000000001954 80.0
HKD2_k127_9228760_15 - - - - 0.000000000009961 74.0
HKD2_k127_9228760_2 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 597.0
HKD2_k127_9228760_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 549.0
HKD2_k127_9228760_4 TIGRFAM cell envelope-related function transcriptional attenuator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 475.0
HKD2_k127_9228760_5 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133,5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000624 439.0
HKD2_k127_9228760_6 TIGRFAM cell envelope-related function transcriptional attenuator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001264 281.0
HKD2_k127_9228760_7 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - - 0.00000000000000000000000000000000000000000000000000000000000000001325 244.0
HKD2_k127_9228760_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000001117 239.0
HKD2_k127_9228760_9 MarR family - - - 0.000000000000000000000000000000007636 130.0
HKD2_k127_9244610_0 - - - - 0.00000000000000000000000003459 123.0
HKD2_k127_9244610_1 - K21687 - - 0.000000000000000002614 91.0
HKD2_k127_9244610_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000003495 62.0
HKD2_k127_9244610_3 Asp23 family, cell envelope-related function - - - 0.000000001164 63.0
HKD2_k127_9247086_0 alpha beta alpha domain I K16881 - 2.7.7.13,5.4.2.8 0.0 1289.0
HKD2_k127_9247086_1 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008731 492.0
HKD2_k127_9247086_10 Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000005165 166.0
HKD2_k127_9247086_11 protein conserved in bacteria - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000004223 162.0
HKD2_k127_9247086_12 TrkA-C domain K07228 - - 0.000000000000000005723 91.0
HKD2_k127_9247086_13 Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0001887 52.0
HKD2_k127_9247086_2 FHA domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 305.0
HKD2_k127_9247086_3 Bifunctional nuclease K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 291.0
HKD2_k127_9247086_4 SMART regulatory protein, MerR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000221 285.0
HKD2_k127_9247086_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000447 279.0
HKD2_k127_9247086_6 PFAM regulatory protein, MerR - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003595 272.0
HKD2_k127_9247086_7 pfam nlp p60 - - - 0.000000000000000000000000000000000000000000000000000001066 207.0
HKD2_k127_9247086_8 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000007891 191.0
HKD2_k127_9247086_9 Protein of unknown function (DUF1290) - - - 0.000000000000000000000000000000000000000000001012 181.0
HKD2_k127_9249364_0 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 495.0
HKD2_k127_9249364_1 UDP binding domain K02472,K13015 - 1.1.1.136,1.1.1.336 0.000000000000000009543 84.0
HKD2_k127_9251043_0 Glucodextranase, domain N K01178 - 3.2.1.3 8.112e-275 883.0
HKD2_k127_9251043_1 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 366.0
HKD2_k127_9251043_2 lipopolysaccharide transmembrane transporter activity K07058 - - 0.0000000000037 80.0
HKD2_k127_9260788_0 Nitrite reductase NAD(P)H , large subunit K00362 - 1.7.1.15 0.0 1112.0
HKD2_k127_9260788_1 Molybdopterin oxidoreductase Fe4S4 domain K00372 - - 3.248e-319 990.0
HKD2_k127_9260788_10 TIGRFAM nitrite reductase NAD(P)H , small subunit K00363 - 1.7.1.15 0.0000000000000000000000000000000704 142.0
HKD2_k127_9260788_11 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000000000000000001696 104.0
HKD2_k127_9260788_12 PFAM plasmid stabilization system - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000001989 102.0
HKD2_k127_9260788_13 - - - - 0.000000000000000000003097 100.0
HKD2_k127_9260788_14 PIN domain - - - 0.000000000000000000008751 99.0
HKD2_k127_9260788_15 manually curated - - - 0.00000000000000005157 80.0
HKD2_k127_9260788_16 - - - - 0.000000000000003557 79.0
HKD2_k127_9260788_17 Antitoxin component of a toxin-antitoxin (TA) module K19159 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.00000000000002871 76.0
HKD2_k127_9260788_2 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 1.246e-236 747.0
HKD2_k127_9260788_20 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000002025 62.0
HKD2_k127_9260788_21 PFAM Transposase DDE domain - - - 0.0003034 46.0
HKD2_k127_9260788_3 Uroporphyrinogen III synthase HEM4 K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 539.0
HKD2_k127_9260788_4 BFD-like [2Fe-2S] binding domain K00360 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 514.0
HKD2_k127_9260788_5 PFAM Major Facilitator Superfamily K02575 GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015112,GO:0015113,GO:0015318,GO:0015698,GO:0015706,GO:0015707,GO:0022857,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0098656,GO:1902025 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 434.0
HKD2_k127_9260788_6 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 430.0
HKD2_k127_9260788_7 SMART regulatory protein GntR HTH K03710 - - 0.0000000000000000000000000000000000000000000000000000004542 202.0
HKD2_k127_9260788_8 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000009229 144.0
HKD2_k127_9260788_9 Toxic component of a toxin-antitoxin (TA) module K07171 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.000000000000000000000000000000002306 146.0
HKD2_k127_9262622_0 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 6.858e-241 775.0
HKD2_k127_9262622_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 519.0
HKD2_k127_9262622_2 - - - - 0.0008668 53.0
HKD2_k127_9268424_0 Transcriptional regulator - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 435.0
HKD2_k127_9268424_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002972 263.0
HKD2_k127_9268424_2 Transcriptional regulator - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000006129 119.0
HKD2_k127_9268424_3 Putative stress-induced transcription regulator - - - 0.00000002186 62.0
HKD2_k127_9274542_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.031e-239 750.0
HKD2_k127_9274542_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 2.906e-232 737.0
HKD2_k127_9274542_10 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000003021 173.0
HKD2_k127_9274542_11 - - - - 0.000000000000000000000000000001077 137.0
HKD2_k127_9274542_12 - K02116 - - 0.000000000000000001235 94.0
HKD2_k127_9274542_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 542.0
HKD2_k127_9274542_3 PFAM Glycosyl transferase family 4 K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 544.0
HKD2_k127_9274542_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 524.0
HKD2_k127_9274542_5 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 494.0
HKD2_k127_9274542_6 homoserine dehydrogenase K00003,K12524 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009692 450.0
HKD2_k127_9274542_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 334.0
HKD2_k127_9274542_8 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 302.0
HKD2_k127_9274542_9 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 321.0
HKD2_k127_9297991_0 Histidine kinase K07768 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 480.0
HKD2_k127_9297991_1 Response regulator receiver K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 396.0
HKD2_k127_9297991_2 PFAM Ppx GppA phosphatase K01524 GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000003154 262.0
HKD2_k127_9297991_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000006002 217.0
HKD2_k127_9308621_0 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 316.0
HKD2_k127_9308621_1 - - - - 0.0000000000000000000000000000000000000000000000000000003202 201.0
HKD2_k127_9320998_0 prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 484.0
HKD2_k127_9320998_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 488.0
HKD2_k127_9320998_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 374.0
HKD2_k127_9320998_3 Belongs to the pseudouridine synthase RsuA family K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 359.0
HKD2_k127_9320998_4 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 304.0
HKD2_k127_9320998_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 293.0
HKD2_k127_9320998_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005776 247.0
HKD2_k127_9320998_7 Chorismate mutase type I K06208 - 5.4.99.5 0.00000000000000000000000000000000000000000000000003442 181.0
HKD2_k127_9320998_8 Peptidase M50 - - - 0.0000000001998 61.0
HKD2_k127_9331395_0 PFAM Peptidase M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 572.0
HKD2_k127_9331395_1 IrrE N-terminal-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 343.0
HKD2_k127_9331395_2 NADH pyrophosphatase K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000001703 266.0
HKD2_k127_9331395_3 ANTAR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006935 253.0
HKD2_k127_9331395_4 Glutaredoxin K18917 - 1.20.4.3 0.0000000000000000000000000001181 117.0
HKD2_k127_9331395_6 helicase K03657 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 0.0000000000000000006181 90.0
HKD2_k127_9331395_7 PFAM Peptidase M16 - - - 0.00000000000005288 72.0
HKD2_k127_9332415_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 1.095e-300 940.0
HKD2_k127_9332415_1 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 610.0
HKD2_k127_9332415_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002836 263.0
HKD2_k127_9332415_3 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000252 192.0
HKD2_k127_9337223_0 CoA-transferase family III K14470 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0015977,GO:0016853,GO:0016866,GO:0016867,GO:0043427,GO:0071704 5.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 559.0
HKD2_k127_9337223_1 belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 466.0
HKD2_k127_9337223_2 Acyl dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 366.0
HKD2_k127_9337223_3 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001325 281.0
HKD2_k127_9337223_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000349 214.0
HKD2_k127_9337223_5 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000002557 211.0
HKD2_k127_9337223_6 YCII-related domain - - - 0.0000000000000000000000000000000000004707 144.0
HKD2_k127_9337223_7 Lsr2 - - - 0.0000000000000000000000000000904 119.0
HKD2_k127_9360119_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 398.0
HKD2_k127_9360119_1 response regulator K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 306.0
HKD2_k127_9360119_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 302.0
HKD2_k127_9360119_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006315 286.0
HKD2_k127_9360119_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000112 215.0
HKD2_k127_9360119_5 ABC transporter (Permease) K01992 - - 0.00000000000000000000000000000000000000000000000002748 186.0
HKD2_k127_9360119_6 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000000000008817 109.0
HKD2_k127_9360119_7 - - - - 0.0000000381 61.0
HKD2_k127_9370449_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 304.0
HKD2_k127_9379479_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 5.439e-209 667.0
HKD2_k127_9379479_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 578.0
HKD2_k127_9379479_10 Filamentation induced by cAMP protein fic - - - 0.0000000000000000000000000000000000000000000000000000000000000008875 242.0
HKD2_k127_9379479_11 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000004495 205.0
HKD2_k127_9379479_12 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000018 167.0
HKD2_k127_9379479_13 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000002015 94.0
HKD2_k127_9379479_2 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 428.0
HKD2_k127_9379479_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 422.0
HKD2_k127_9379479_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 378.0
HKD2_k127_9379479_5 RibD C-terminal domain K00082,K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 407.0
HKD2_k127_9379479_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 334.0
HKD2_k127_9379479_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 301.0
HKD2_k127_9379479_8 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000003066 255.0
HKD2_k127_9379479_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0040007,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000218 228.0
HKD2_k127_9391454_0 Protein of unknown function (DUF3618) - - - 0.0000000000000000000000000000000000000000000000000008013 199.0
HKD2_k127_9391454_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000001429 152.0
HKD2_k127_9391454_2 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000000000000000000004528 134.0
HKD2_k127_9391454_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.000000000000000000000000000005926 128.0
HKD2_k127_9419333_0 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 361.0
HKD2_k127_9419333_1 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001032 277.0
HKD2_k127_9419333_2 RNA polymerase K03090 GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000009757 190.0
HKD2_k127_9419333_3 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.00000000000000000000000000000000006938 136.0
HKD2_k127_9419333_4 - - - - 0.0000000000000000000000000000006647 125.0
HKD2_k127_9445915_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1603.0
HKD2_k127_9445915_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 310.0
HKD2_k127_9445915_10 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000772 98.0
HKD2_k127_9445915_11 CRISPR-associated protein Cas2 K09951 - - 0.0000000000000000001297 89.0
HKD2_k127_9445915_13 CRISPR-associated protein (Cas_Cas2CT1978) K09951 - - 0.000001924 54.0
HKD2_k127_9445915_14 required for the transposition of insertion element IS2404 - - - 0.000005682 48.0
HKD2_k127_9445915_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006413 268.0
HKD2_k127_9445915_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001883 256.0
HKD2_k127_9445915_4 Protein of unknown function (DUF3052) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001386 235.0
HKD2_k127_9445915_5 Domain of unknown function (DUF4234) - - - 0.000000000000000000000000000000000000000000000000000000000000003301 223.0
HKD2_k127_9445915_6 Uncharacterised protein family UPF0047 - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000003452 208.0
HKD2_k127_9445915_7 - - - - 0.000000000000000000000000000000000000000836 162.0
HKD2_k127_9445915_8 Protein of unknown function (DUF2795) - - - 0.00000000000000000000000000000000000482 142.0
HKD2_k127_9445915_9 - - - - 0.00000000000000000000000000049 125.0
HKD2_k127_9448708_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 354.0
HKD2_k127_9448708_1 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 322.0
HKD2_k127_9448708_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000007223 213.0
HKD2_k127_9448708_3 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000463 207.0
HKD2_k127_9448708_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001211 163.0
HKD2_k127_9448708_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000007671 100.0
HKD2_k127_9456793_0 PFAM glycoside hydrolase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001912 261.0
HKD2_k127_9483155_0 Fungal family of unknown function (DUF1776) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 322.0
HKD2_k127_9483155_1 bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 307.0
HKD2_k127_9483155_2 S-adenosyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001436 290.0
HKD2_k127_9483155_3 Pyridoxal-dependent decarboxylase conserved domain K13745 - 4.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002713 277.0
HKD2_k127_9483155_4 Restriction endonuclease K07448 - - 0.0000000000000000000000000000000000003455 148.0
HKD2_k127_9483155_5 intracellular protease amidase - - - 0.0000000000008739 80.0
HKD2_k127_9483155_7 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0009644 52.0
HKD2_k127_954422_0 PFAM amine oxidase K01854 - 5.4.99.9 1.311e-276 859.0
HKD2_k127_954422_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01144,K03581 - 3.1.11.5 1.892e-233 737.0
HKD2_k127_954422_10 Phosphatidylinositol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 346.0
HKD2_k127_954422_11 phosphoglycerate mutase K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 325.0
HKD2_k127_954422_12 PFAM Peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 299.0
HKD2_k127_954422_13 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000001562 218.0
HKD2_k127_954422_14 - - - - 0.000000000000000000000000001352 117.0
HKD2_k127_954422_15 toxin-antitoxin pair type II binding - - - 0.000000000000001809 79.0
HKD2_k127_954422_16 PIN domain - - - 0.00000001187 58.0
HKD2_k127_954422_17 PIN domain - - - 0.00000001828 66.0
HKD2_k127_954422_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 3.07e-224 713.0
HKD2_k127_954422_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 2.578e-196 632.0
HKD2_k127_954422_4 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 498.0
HKD2_k127_954422_5 Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 490.0
HKD2_k127_954422_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 GO:0006950,GO:0008150,GO:0050896,GO:0051409 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 426.0
HKD2_k127_954422_7 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 417.0
HKD2_k127_954422_8 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 375.0
HKD2_k127_954422_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 381.0
HKD2_k127_9579345_0 Ribosomal protein L11 methyltransferase (PrmA) K11434,K19737,K21170 - 2.1.1.319,2.1.1.320 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 506.0
HKD2_k127_9579345_1 Lanthionine synthetase C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002463 287.0
HKD2_k127_9579345_2 ATP diphosphatase activity K09136 - - 0.0000000000000000000000000000000000000000000000000000867 208.0
HKD2_k127_9579345_3 phosphopantothenoylcysteine decarboxylase activity K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000309 189.0
HKD2_k127_9579345_4 very-long-chain-acyl-CoA dehydrogenase activity K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000002183 185.0
HKD2_k127_9579345_5 Phosphotransferase enzyme family - - - 0.000000000000000000000000002357 126.0
HKD2_k127_9579345_6 - - - - 0.00000000000000000004804 96.0
HKD2_k127_9579345_7 Winged helix-turn helix - - - 0.0002496 43.0
HKD2_k127_9585922_0 Arginine K01478 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 511.0
HKD2_k127_9585922_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 490.0
HKD2_k127_9585922_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 431.0
HKD2_k127_9585922_3 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 398.0
HKD2_k127_9585922_4 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 341.0
HKD2_k127_9585922_5 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 294.0
HKD2_k127_9585922_6 Phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000006344 186.0
HKD2_k127_9585922_7 Iron-containing redox enzyme - - - 0.00000000000000000000000000001377 132.0
HKD2_k127_9710458_0 MMPL family K06994 - - 3.027e-260 822.0
HKD2_k127_9710458_1 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 468.0
HKD2_k127_9710458_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000001298 229.0
HKD2_k127_9710458_3 - - - - 0.0000000000000000000000000001046 120.0
HKD2_k127_9712679_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000001481 151.0
HKD2_k127_9712679_1 Ketosteroid isomerase-related protein - - - 0.000000000000000000000000000000000000003666 154.0
HKD2_k127_9712679_2 the current gene model (or a revised gene model) may contain a frame shift - - - 0.00000000000000000000000000000000000002087 151.0
HKD2_k127_9712679_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000003252 105.0
HKD2_k127_9712679_4 B3 4 domain - - - 0.00000000000002618 78.0
HKD2_k127_9712679_5 - - - - 0.000000001817 64.0
HKD2_k127_9712679_6 Protein of unknown function (DUF4232) - - - 0.00000001096 65.0
HKD2_k127_9712679_7 Lsr2 - - - 0.0002792 51.0
HKD2_k127_9715441_0 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 403.0
HKD2_k127_9715441_1 Cupin 4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 369.0
HKD2_k127_9715441_2 Isochorismatase family K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000001718 228.0
HKD2_k127_9715441_3 Sucrase/ferredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000009916 220.0
HKD2_k127_9715441_4 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000002843 156.0
HKD2_k127_9715441_5 CrcB-like protein, Camphor Resistance (CrcB) K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000004857 136.0
HKD2_k127_9715441_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000002462 120.0
HKD2_k127_9715441_7 Domain of unknown function (DUF4193) - - - 0.00000000000001565 72.0
HKD2_k127_9720546_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 1.683e-310 963.0
HKD2_k127_9720546_1 Belongs to the aldehyde dehydrogenase family K00138,K18370 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 6.19e-285 887.0
HKD2_k127_9720546_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004982 289.0
HKD2_k127_9720546_11 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003521 280.0
HKD2_k127_9720546_12 Electron transfer flavoprotein alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008974 289.0
HKD2_k127_9720546_13 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000002825 239.0
HKD2_k127_9720546_14 Protein of unknown function (DUF779) K09959 - - 0.00000000000000000000000000000000000000000000000000000002802 204.0
HKD2_k127_9720546_15 Stress protein K05792 - - 0.000000000000000000000000000000000000000000000000000000175 200.0
HKD2_k127_9720546_16 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K03855 - - 0.00000000000000000000000000000000000000002203 171.0
HKD2_k127_9720546_17 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000005601 151.0
HKD2_k127_9720546_18 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000005249 92.0
HKD2_k127_9720546_2 COG COG1454 Alcohol dehydrogenase class IV Energy production and conversion K00048,K17067 - 1.1.1.77,1.1.99.37,1.2.98.1 7.372e-235 732.0
HKD2_k127_9720546_3 NADH:flavin oxidoreductase / NADH oxidase family - - - 9.682e-204 671.0
HKD2_k127_9720546_4 Radical SAM - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 553.0
HKD2_k127_9720546_5 geranylgeranyl reductase activity K00313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 591.0
HKD2_k127_9720546_6 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 540.0
HKD2_k127_9720546_7 PFAM Iron-containing alcohol dehydrogenase K00086,K11440 - 1.1.1.1,1.1.1.202 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 482.0
HKD2_k127_9720546_8 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 462.0
HKD2_k127_9720546_9 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005275 291.0
HKD2_k127_9731933_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 530.0
HKD2_k127_9731933_1 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 439.0
HKD2_k127_9731933_2 helix_turn_helix, Lux Regulon - - - 0.0000000000002967 76.0
HKD2_k127_978306_0 DoxX family K15977 - - 0.00000000000000000000000000000000000000000000000000000005153 201.0
HKD2_k127_978306_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000002288 176.0
HKD2_k127_978306_2 Major facilitator superfamily - - - 0.000000000000000000000000000004988 137.0
HKD2_k127_978306_3 - - - - 0.000000007205 68.0
HKD2_k127_978306_4 Uncharacterized ACR, COG1993 K09137 - - 0.0000001096 60.0
HKD2_k127_978306_5 His Kinase A (phosphoacceptor) domain - - - 0.000007373 57.0
HKD2_k127_978334_0 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 426.0
HKD2_k127_978334_1 carboxylic ester hydrolase activity K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000000000000000002334 226.0
HKD2_k127_978334_2 RDD domain containing protein - - - 0.0001658 50.0
HKD2_k127_9807802_0 MacB-like periplasmic core domain K02004 - - 2.165e-255 809.0
HKD2_k127_9807802_1 ABC transporter substrate-binding protein K02027,K10232 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 380.0
HKD2_k127_9807802_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 325.0
HKD2_k127_9807802_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05845 - - 0.000000000000000000000000000000000000000000000000000000000008005 217.0
HKD2_k127_9810825_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.5.1.6 9.158e-226 707.0
HKD2_k127_9810825_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 555.0
HKD2_k127_9810825_2 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 - 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 432.0
HKD2_k127_9810825_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 353.0
HKD2_k127_9810825_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 315.0
HKD2_k127_9810825_5 Dihydroorotate oxidase K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001509 266.0
HKD2_k127_9810825_6 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000296 281.0
HKD2_k127_9810825_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 0.000000000000000000000000000000000000000000324 171.0
HKD2_k127_9810825_8 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.000000000000000000000000000000000000000007174 158.0
HKD2_k127_981135_0 histidine kinase, dimerisation phosphoacceptor K00936 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 2.07e-219 690.0
HKD2_k127_981135_1 Aminotransferase class-III K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 535.0
HKD2_k127_981135_2 aminotransferase class I and II K00652,K01906 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.47,6.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 496.0
HKD2_k127_981135_3 vWA found in TerF C terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 441.0
HKD2_k127_981135_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000007761 194.0
HKD2_k127_981135_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000007115 175.0
HKD2_k127_981135_6 Transcription factor WhiB K18955 GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000116 106.0
HKD2_k127_9824119_0 HypF finger K04656 - - 7.227e-302 946.0
HKD2_k127_9824119_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 5.22e-296 926.0
HKD2_k127_9824119_10 - - - - 0.00000000000000000000000000143 122.0
HKD2_k127_9824119_12 PFAM Glutamine synthetase, catalytic K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.000000000000000000000003974 106.0
HKD2_k127_9824119_2 Transmembrane secretion effector K05557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 590.0
HKD2_k127_9824119_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 391.0
HKD2_k127_9824119_4 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 382.0
HKD2_k127_9824119_5 Belongs to the AAA ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 383.0
HKD2_k127_9824119_6 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000001685 229.0
HKD2_k127_9824119_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000001815 223.0
HKD2_k127_9824119_8 Alpha/beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000002856 239.0
HKD2_k127_9824119_9 - - - - 0.0000000000000000000000000000000000000000000000005714 180.0
HKD2_k127_9825307_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 2.968e-290 897.0
HKD2_k127_9825307_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009394 577.0
HKD2_k127_9825307_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 543.0
HKD2_k127_9825307_3 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 526.0
HKD2_k127_9825307_4 PFAM binding-protein-dependent transport systems inner membrane component K02033,K13890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 506.0
HKD2_k127_9825307_5 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 524.0
HKD2_k127_9825307_6 dehydrogenase subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 463.0
HKD2_k127_9825307_7 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 362.0
HKD2_k127_9825307_8 Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters - - - 0.00000000000000000000000000000000000000000000000000000000004732 208.0
HKD2_k127_9825307_9 PFAM Preprotein translocase SecG subunit K03075 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000007592 111.0
HKD2_k127_9842391_0 Elongation factor G, domain IV K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 1.011e-314 981.0
HKD2_k127_9842391_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.426e-295 919.0
HKD2_k127_9842391_2 PFAM Glycosyl transferase, group 1 K08256 GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 578.0
HKD2_k127_9842391_3 lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 434.0
HKD2_k127_9842391_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K00999 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 311.0
HKD2_k127_9842391_5 PFAM Histidine triad (HIT) protein K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003067 301.0
HKD2_k127_9842391_6 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000129 223.0
HKD2_k127_9842391_7 LemA family - - - 0.0000000000000000000000000000000000000174 149.0
HKD2_k127_9842391_8 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.000000004182 65.0
HKD2_k127_9882307_0 AAA domain K07028 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 550.0
HKD2_k127_9882307_1 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000008892 234.0
HKD2_k127_9882307_2 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000001669 149.0