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Overview

ID MAG01818
Name HKD2_bin.75
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Bacillota
Class Clostridia
Order Lutisporales
Family Lutisporaceae
Genus GWB2-37-7
Species
Assembly information
Completeness (%) 93.64
Contamination (%) 8.63
GC content (%) 37.0
N50 (bp) 9,300
Genome size (bp) 3,141,120

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3054

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10003951_0 Glycosyltransferase 36 associated - - - 0.0 1345.0
HKD2_k127_10151540_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 571.0
HKD2_k127_10151540_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 385.0
HKD2_k127_10151540_2 SAM-dependent methyltransferase K06967 - 2.1.1.217 0.0000000000000000000000000000000000000000000000000003432 192.0
HKD2_k127_10151540_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000005153 151.0
HKD2_k127_10151540_4 - - - - 0.00000008438 53.0
HKD2_k127_10167296_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 1.296e-198 623.0
HKD2_k127_10167296_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 519.0
HKD2_k127_10167296_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 499.0
HKD2_k127_10167296_3 TIGRFAM SpoIID LytB domain K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 364.0
HKD2_k127_10167296_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000009996 171.0
HKD2_k127_10167296_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000002122 102.0
HKD2_k127_10167296_6 Preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000005385 104.0
HKD2_k127_10167296_7 RSAM-modified six-cysteine peptide - - - 0.00000000000000005929 81.0
HKD2_k127_1235778_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000005122 194.0
HKD2_k127_1235778_1 - K03641 - - 0.00000000000000000000000000001524 124.0
HKD2_k127_1235778_2 Belongs to the sigma-70 factor family - - - 0.000000000000000000005434 94.0
HKD2_k127_1235778_3 YvrJ protein family - - - 0.00000000000000000005627 91.0
HKD2_k127_1235778_4 - - - - 0.000000000000001933 85.0
HKD2_k127_1284591_0 Glyco_18 K06306 - - 3.019e-227 711.0
HKD2_k127_1284591_1 Sodium/hydrogen exchanger family K11105 - - 2.141e-211 665.0
HKD2_k127_1284591_10 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000004236 171.0
HKD2_k127_1284591_11 PFAM FMN-binding domain - - - 0.000000000000000000000002069 107.0
HKD2_k127_1284591_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 5.695e-209 668.0
HKD2_k127_1284591_3 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 446.0
HKD2_k127_1284591_4 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 403.0
HKD2_k127_1284591_5 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 323.0
HKD2_k127_1284591_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 311.0
HKD2_k127_1284591_7 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002509 281.0
HKD2_k127_1284591_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008401 259.0
HKD2_k127_1284591_9 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000000002579 182.0
HKD2_k127_1284990_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.718e-308 958.0
HKD2_k127_1284990_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 565.0
HKD2_k127_1284990_2 coproporphyrinogen III oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 449.0
HKD2_k127_1284990_3 exonuclease K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 410.0
HKD2_k127_1284990_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000001187 245.0
HKD2_k127_1284990_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000000003278 205.0
HKD2_k127_1284990_6 domain protein - - - 0.000000000000000000000000000000000000000000000000000000002472 205.0
HKD2_k127_1284990_7 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000007963 83.0
HKD2_k127_1286680_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 531.0
HKD2_k127_1286680_1 Cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 479.0
HKD2_k127_1286680_2 -hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 463.0
HKD2_k127_1324727_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.028e-282 883.0
HKD2_k127_1324727_1 Flagellar protein export ATPase FliI K02412,K03224 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 611.0
HKD2_k127_1324727_10 Flagellar hook-basal body complex protein FliE - - - 0.00000000000000000000379 96.0
HKD2_k127_1324727_11 PFAM Flagellar assembly protein FliH Type III secretion system HrpE K02411 - - 0.0000000000000000004905 96.0
HKD2_k127_1324727_12 TIGRFAM flagellar export protein FliJ K02413 - - 0.0000000000000003276 84.0
HKD2_k127_1324727_13 MgtE intracellular N domain K02383 - - 0.00000006086 62.0
HKD2_k127_1324727_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 595.0
HKD2_k127_1324727_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 586.0
HKD2_k127_1324727_4 flagellar motor switch protein K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 537.0
HKD2_k127_1324727_5 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor K03706 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 343.0
HKD2_k127_1324727_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002119 268.0
HKD2_k127_1324727_7 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001774 270.0
HKD2_k127_1324727_8 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000000000000004143 222.0
HKD2_k127_1324727_9 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000002111 130.0
HKD2_k127_1333816_0 Methyltransferase K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 355.0
HKD2_k127_1333816_1 Glyoxalase K04750 - - 0.000000000000000000000005553 106.0
HKD2_k127_1333816_2 - - - - 0.0000005513 51.0
HKD2_k127_1333816_3 rod shape-determining protein mreB K03569 - - 0.000002418 58.0
HKD2_k127_1335411_0 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 482.0
HKD2_k127_1335411_1 Psort location Cytoplasmic, score K06400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 299.0
HKD2_k127_1335411_2 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007177 254.0
HKD2_k127_1335411_3 DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000003545 248.0
HKD2_k127_1335411_4 Region found in RelA / SpoT proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000005137 243.0
HKD2_k127_1335411_5 PFAM D-isomer specific 2-hydroxyacid dehydrogenase K06410 - - 0.00000000000000000000000000000000000000000000000000000000000001103 227.0
HKD2_k127_1335411_6 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000009285 172.0
HKD2_k127_1335411_7 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA) K06411 - - 0.00000000000000000000000000000003388 128.0
HKD2_k127_1335411_8 PRC-barrel domain - - - 0.00000000000000000007823 91.0
HKD2_k127_1350952_0 aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 565.0
HKD2_k127_1350952_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 487.0
HKD2_k127_1350952_10 adenosyltransferase K00798 - 2.5.1.17 0.0000002499 53.0
HKD2_k127_1350952_2 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 379.0
HKD2_k127_1350952_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003253 278.0
HKD2_k127_1350952_4 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000001469 232.0
HKD2_k127_1350952_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000002955 212.0
HKD2_k127_1350952_6 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000000000000003051 145.0
HKD2_k127_1350952_7 Helix-turn-helix domain - - - 0.000000000000000000000000000009659 125.0
HKD2_k127_1350952_8 PFAM Rubredoxin-type Fe(Cys)4 protein - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0017144,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114,GO:0072592 - 0.0000000000000000000000000002042 114.0
HKD2_k127_1350952_9 Domain of Unknown Function (DUF1540) - - - 0.00000001092 58.0
HKD2_k127_1366360_0 import. Responsible for energy coupling to the transport system K10441,K10542 - 3.6.3.17 9.46e-214 674.0
HKD2_k127_1366360_1 PFAM periplasmic binding protein K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 444.0
HKD2_k127_1366360_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001479 226.0
HKD2_k127_1366360_11 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000000000000000001452 169.0
HKD2_k127_1366360_12 spore coat protein, CotS K06331,K06337 - - 0.000000000000000000000000000000000000000002976 168.0
HKD2_k127_1366360_13 spore coat protein, CotS K06331,K06337 - - 0.0000000000000000000000000002208 127.0
HKD2_k127_1366360_14 cluster protein-associated redox disulfide domain - - - 0.00000000000000000000005606 98.0
HKD2_k127_1366360_15 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000004764 81.0
HKD2_k127_1366360_16 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose K06726 - 5.4.99.62 0.00000000002146 64.0
HKD2_k127_1366360_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 418.0
HKD2_k127_1366360_3 mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008549 402.0
HKD2_k127_1366360_4 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 388.0
HKD2_k127_1366360_5 PFAM Nitroreductase K07078 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 301.0
HKD2_k127_1366360_6 Ami_3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 306.0
HKD2_k127_1366360_7 sporulation peptidase YabG K06436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 299.0
HKD2_k127_1366360_8 Spore coat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002027 273.0
HKD2_k127_1366360_9 spore coat protein, CotS K06331,K06337 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001141 253.0
HKD2_k127_1374806_0 Virulence activator alpha C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 508.0
HKD2_k127_1374806_1 phosphoenolpyruvate synthase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 319.0
HKD2_k127_1374806_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000004009 84.0
HKD2_k127_1374806_3 Psort location Cytoplasmic, score - - - 0.000000004149 59.0
HKD2_k127_137809_0 Spore germination protein K06295,K06310 - - 4.684e-221 693.0
HKD2_k127_137809_1 Putative RNA methylase family UPF0020 - - - 0.000000000000000000000000000000000000000000000000000000002411 201.0
HKD2_k127_1383921_0 family 39 K01198 - 3.2.1.37 1.358e-199 643.0
HKD2_k127_1383921_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 440.0
HKD2_k127_1393320_0 Glycosyltransferase family 36 - - - 0.0 2931.0
HKD2_k127_1393320_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 377.0
HKD2_k127_1393320_2 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 317.0
HKD2_k127_1393320_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002565 260.0
HKD2_k127_1393320_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000003778 170.0
HKD2_k127_1393320_5 Belongs to the UPF0297 family - - - 0.000000000000000000000000000006302 121.0
HKD2_k127_1401867_0 Aminotransferase class I and II K09758 - 4.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 574.0
HKD2_k127_1401867_1 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000003846 191.0
HKD2_k127_1404349_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 9.451e-267 830.0
HKD2_k127_1404349_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 375.0
HKD2_k127_1404349_2 TIGRFAM arsenite-activated ATPase ArsA K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 363.0
HKD2_k127_1404349_3 MarR family - - - 0.00000000000000000000000000000000000000000000000000005787 190.0
HKD2_k127_1404349_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000003079 147.0
HKD2_k127_1404705_0 Peptidase family U32 K08303 - - 2.83e-306 949.0
HKD2_k127_1404705_1 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 1.936e-292 900.0
HKD2_k127_1404705_10 - - - - 0.00000000000000000000000002175 115.0
HKD2_k127_1404705_11 Psort location Cytoplasmic, score - - - 0.0000000000000009893 78.0
HKD2_k127_1404705_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K00823,K07250 GO:0003674,GO:0003824,GO:0003867,GO:0008483,GO:0016740,GO:0016769 2.6.1.19,2.6.1.22,4.1.1.64 4.799e-199 627.0
HKD2_k127_1404705_3 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 409.0
HKD2_k127_1404705_4 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 389.0
HKD2_k127_1404705_5 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 374.0
HKD2_k127_1404705_6 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 339.0
HKD2_k127_1404705_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 302.0
HKD2_k127_1404705_8 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 283.0
HKD2_k127_1404705_9 YcxB-like protein - - - 0.00000000000000000000000000000000000000000001744 167.0
HKD2_k127_1405826_0 oxidoreductase activity K07114 - - 5.138e-286 904.0
HKD2_k127_1405826_1 oligoendopeptidase, M3 family - - - 2.086e-278 865.0
HKD2_k127_1405826_2 Psort location Cytoplasmic, score 7.50 K01478 - 3.5.3.6 4.831e-224 699.0
HKD2_k127_1405826_3 PFAM aminotransferase class I and II K11358 - 2.6.1.1 6.729e-201 631.0
HKD2_k127_1405826_4 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 504.0
HKD2_k127_1405826_5 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 397.0
HKD2_k127_1405826_6 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 304.0
HKD2_k127_1405826_7 AsnC family K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000002192 235.0
HKD2_k127_1405826_8 - - - - 0.0000000000000000000000000000000000000000000001106 174.0
HKD2_k127_1405826_9 Ami_2 K01447 - 3.5.1.28 0.000006838 59.0
HKD2_k127_1408328_0 Thi4 family - - - 0.0 1186.0
HKD2_k127_1408328_1 Psort location CytoplasmicMembrane, score - - - 7.036e-212 659.0
HKD2_k127_1408328_2 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 403.0
HKD2_k127_1408328_3 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 386.0
HKD2_k127_1408328_4 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 393.0
HKD2_k127_1408328_5 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 325.0
HKD2_k127_1408328_6 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 308.0
HKD2_k127_1410986_0 Acts as a magnesium transporter K06213 - - 4.222e-202 638.0
HKD2_k127_1410986_1 Protein of unknown function (DUF3298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 481.0
HKD2_k127_1410986_2 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004108 258.0
HKD2_k127_1410986_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001672 267.0
HKD2_k127_1410986_4 virulence-associated E family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000447 237.0
HKD2_k127_1410986_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000005906 221.0
HKD2_k127_1410986_6 virulence-associated E family protein - - - 0.0000000000000000000000000000000000000000000000000000000000001033 216.0
HKD2_k127_1410986_7 - - - - 0.000000000000000000000000000000000003817 141.0
HKD2_k127_1410986_8 - - - - 0.0000000000000000000000007995 106.0
HKD2_k127_1435707_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 527.0
HKD2_k127_1435707_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000001758 171.0
HKD2_k127_1453301_0 phosphate butyryltransferase K00634 - 2.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 342.0
HKD2_k127_1453301_1 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 293.0
HKD2_k127_1453301_2 LUD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002208 229.0
HKD2_k127_1453889_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 1.517e-220 691.0
HKD2_k127_1453889_1 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000003903 182.0
HKD2_k127_1453889_2 Polymer-forming cytoskeletal - - - 0.000000000000000000004703 98.0
HKD2_k127_1469475_0 Branched-chain amino acid aminotransferase K00826,K02619 - 2.6.1.42,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 597.0
HKD2_k127_1469475_1 transcription activator, effector binding K13653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 323.0
HKD2_k127_1469475_2 Threonyl and Alanyl tRNA synthetase second additional domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 312.0
HKD2_k127_1469475_3 transcription activator, effector binding K13653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 308.0
HKD2_k127_1469475_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 310.0
HKD2_k127_1469475_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009827 266.0
HKD2_k127_1469475_6 5'-3' exonuclease, SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000002352 219.0
HKD2_k127_1469475_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000009086 203.0
HKD2_k127_1469475_8 protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000005802 132.0
HKD2_k127_1469475_9 Protein of unknown function (DUF3795) - - - 0.0000000000000000000003225 100.0
HKD2_k127_1474168_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008688 517.0
HKD2_k127_1474168_1 Heme response regulator HssR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 343.0
HKD2_k127_1474168_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 322.0
HKD2_k127_1474168_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000002645 68.0
HKD2_k127_1481596_0 Protein of unknown function (DUF3298) - - - 7.596e-308 963.0
HKD2_k127_1481596_1 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22341 - 1.17.1.11,1.17.1.9 3.386e-234 735.0
HKD2_k127_1481596_2 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 7.984e-231 729.0
HKD2_k127_1481596_3 decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 576.0
HKD2_k127_1481596_4 Mate efflux family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 499.0
HKD2_k127_1481596_5 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 505.0
HKD2_k127_1481596_6 transcriptional regulator K21900 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 312.0
HKD2_k127_1481596_7 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004443 277.0
HKD2_k127_1481596_8 COG0515 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001041 273.0
HKD2_k127_1481596_9 S-layer homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000304 258.0
HKD2_k127_1483656_0 Propeptide, PepSY - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 464.0
HKD2_k127_1483656_1 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 352.0
HKD2_k127_1483656_2 Glycosyl hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 332.0
HKD2_k127_1483656_3 Coat F domain - - - 0.0000000000000000000000000000000000000000000000000002616 190.0
HKD2_k127_1483656_4 ECF-type riboflavin transporter, S component - - - 0.00000000000000000000000000000000001745 143.0
HKD2_k127_1483656_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.0000000000000000000009048 111.0
HKD2_k127_1483668_0 GH3 auxin-responsive promoter - - - 6.008e-261 811.0
HKD2_k127_1483668_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 469.0
HKD2_k127_1483668_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002609 264.0
HKD2_k127_1497327_0 Heat shock 70 kDa protein K04043 - - 1.612e-207 651.0
HKD2_k127_1497327_1 tRNA methylthiotransferase YqeV K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 536.0
HKD2_k127_1497327_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 478.0
HKD2_k127_1497327_3 UPF0365 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 452.0
HKD2_k127_1497327_4 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 345.0
HKD2_k127_1497327_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000005535 254.0
HKD2_k127_1497327_6 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000003482 179.0
HKD2_k127_1497327_7 Hit family K02503 - - 0.0000000000000000000000000000000000000000007273 159.0
HKD2_k127_1497327_8 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000001886 129.0
HKD2_k127_1497327_9 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000008778 98.0
HKD2_k127_1506997_0 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 554.0
HKD2_k127_1506997_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 362.0
HKD2_k127_1506997_10 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000007588 201.0
HKD2_k127_1506997_11 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000002023 175.0
HKD2_k127_1506997_12 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000000000001022 175.0
HKD2_k127_1506997_13 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000001585 137.0
HKD2_k127_1506997_14 Cobalamin biosynthesis protein CobT VWA domain - - - 0.0000000000000000000001243 112.0
HKD2_k127_1506997_15 Psort location Cytoplasmic, score - - - 0.000000000000001856 82.0
HKD2_k127_1506997_16 Cobalamin biosynthesis protein CobT VWA domain - - - 0.00004318 56.0
HKD2_k127_1506997_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 338.0
HKD2_k127_1506997_3 Hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003239 274.0
HKD2_k127_1506997_4 G5 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005423 252.0
HKD2_k127_1506997_5 helix_turn_helix, cAMP Regulatory protein K10914,K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001933 244.0
HKD2_k127_1506997_6 DMT(Drug metabolite transporter) superfamily permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002556 248.0
HKD2_k127_1506997_7 ECF-type riboflavin transporter, S component - - - 0.00000000000000000000000000000000000000000000000000000000000001131 220.0
HKD2_k127_1506997_8 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000001197 216.0
HKD2_k127_1506997_9 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step K05985 - 3.1.26.8 0.00000000000000000000000000000000000000000000000000000000007427 210.0
HKD2_k127_1507036_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 411.0
HKD2_k127_1507036_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626,K03856,K13853 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 338.0
HKD2_k127_1507036_10 - - - - 0.0000000000000000000000005133 107.0
HKD2_k127_1507036_11 membrane fusion protein - - - 0.00000000000000000001611 105.0
HKD2_k127_1507036_12 Uncharacterized protein family UPF0016 - - - 0.0000000000002924 69.0
HKD2_k127_1507036_13 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000007102 69.0
HKD2_k127_1507036_14 hydrolase K01048 - 3.1.1.5 0.00001587 49.0
HKD2_k127_1507036_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 319.0
HKD2_k127_1507036_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005381 279.0
HKD2_k127_1507036_4 S4 domain protein - - - 0.000000000000000000000000000000000000000000000000000000001549 209.0
HKD2_k127_1507036_5 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000126 198.0
HKD2_k127_1507036_6 PFAM DivIVA family protein K04074 - - 0.000000000000000000000000000000000000000000000001286 177.0
HKD2_k127_1507036_7 TIGRFAM sporulation protein, yteA - - - 0.00000000000000000000000000000000003068 141.0
HKD2_k127_1507036_8 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.00000000000000000000000000000000003596 140.0
HKD2_k127_1507036_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000001777 134.0
HKD2_k127_1513679_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.293e-256 812.0
HKD2_k127_1513679_1 domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000006918 268.0
HKD2_k127_1513679_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000007117 261.0
HKD2_k127_1513679_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000001049 141.0
HKD2_k127_1513679_4 Nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.000000000000000000000000008232 111.0
HKD2_k127_1513679_5 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family - - - 0.000000000000000000000000105 109.0
HKD2_k127_1513679_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000003921 63.0
HKD2_k127_1514006_0 peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 460.0
HKD2_k127_1514006_1 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - 0.0000000000000000192 89.0
HKD2_k127_1514006_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000002126 54.0
HKD2_k127_1517719_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 471.0
HKD2_k127_1517719_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 329.0
HKD2_k127_1517719_2 PFAM histidine kinase, HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000001111 246.0
HKD2_k127_1521375_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 522.0
HKD2_k127_1521375_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 494.0
HKD2_k127_1521375_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 422.0
HKD2_k127_1521375_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 402.0
HKD2_k127_1521375_4 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 362.0
HKD2_k127_1521375_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 329.0
HKD2_k127_1521375_6 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.000000000000000000000000002716 114.0
HKD2_k127_1527639_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1852.0
HKD2_k127_1527639_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 2.711e-280 864.0
HKD2_k127_1527639_2 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000001854 219.0
HKD2_k127_1527639_3 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000002676 211.0
HKD2_k127_1527639_4 - - - - 0.00000000000000000000000000000000000000000000002067 184.0
HKD2_k127_1527639_5 Bacterial Peptidase A24 N-terminal domain - - - 0.000000006864 63.0
HKD2_k127_1532700_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 360.0
HKD2_k127_1532700_1 Histidine kinase - - - 0.00000000000000000000000003161 109.0
HKD2_k127_1534152_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003498 283.0
HKD2_k127_1534152_1 PFAM Methyltransferase K00563 - 2.1.1.187 0.0000000000000000000000000000000000000000000000000000000000000002138 230.0
HKD2_k127_1534152_2 Belongs to the phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000001409 187.0
HKD2_k127_1534152_4 Domain of unknown function (DUF4177) - - - 0.000000000000000000004457 93.0
HKD2_k127_1534152_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00008729 50.0
HKD2_k127_1534215_0 Ribosomal RNA adenine dimethylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 398.0
HKD2_k127_1534215_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 316.0
HKD2_k127_1534215_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 302.0
HKD2_k127_1534215_3 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000254 266.0
HKD2_k127_1534215_4 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002485 251.0
HKD2_k127_1534215_5 peptidase - - - 0.000000000000000000000003263 104.0
HKD2_k127_1534215_6 homoserine kinase type II - - - 0.000006727 48.0
HKD2_k127_1552980_0 pyruvate phosphate dikinase, PEP K01006,K01007 - 2.7.9.1,2.7.9.2 1.325e-249 781.0
HKD2_k127_1552980_1 Radical SAM K07129 - - 2.772e-227 706.0
HKD2_k127_1552980_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 537.0
HKD2_k127_1552980_3 VanZ like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 305.0
HKD2_k127_1552980_4 CGGC - - - 0.00000000000000000000000000000000000000000000000000000001008 201.0
HKD2_k127_1552980_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000003672 139.0
HKD2_k127_1552980_6 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000003061 108.0
HKD2_k127_1552980_7 GHKL domain K18350 - 2.7.13.3 0.00000000005825 62.0
HKD2_k127_155474_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 382.0
HKD2_k127_155474_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 344.0
HKD2_k127_155474_2 ClpP class periplasmic serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 324.0
HKD2_k127_155474_3 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000000000000000007623 226.0
HKD2_k127_155679_0 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 465.0
HKD2_k127_155679_1 Psort location CytoplasmicMembrane, score K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 338.0
HKD2_k127_155679_2 malic enzyme K00027 - 1.1.1.38 0.000000000000000000003518 93.0
HKD2_k127_155679_3 aldo keto reductase K07079 - - 0.000000000000008515 75.0
HKD2_k127_1584237_0 hmm pf06738 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003147 243.0
HKD2_k127_1584237_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000002636 218.0
HKD2_k127_1584237_2 Threonine/Serine exporter, ThrE - - - 0.0000000000000000000000000000000000000003525 153.0
HKD2_k127_1584237_3 - - - - 0.0000000002404 72.0
HKD2_k127_1584237_4 Sortilin, neurotensin receptor 3, - - - 0.000005988 58.0
HKD2_k127_1585049_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.313e-245 775.0
HKD2_k127_1585049_1 ATP-dependent DNA helicase K03657 - 3.6.4.12 1.125e-234 741.0
HKD2_k127_1585049_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 580.0
HKD2_k127_1585049_3 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 501.0
HKD2_k127_1585049_4 binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 338.0
HKD2_k127_1585049_5 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000001085 212.0
HKD2_k127_1586500_0 -hydrogenase K00533 - 1.12.7.2 3.161e-232 726.0
HKD2_k127_1586500_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 1.307e-230 726.0
HKD2_k127_1586500_10 NAD+ diphosphatase activity K03426,K20449 - 1.3.7.1,3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004346 275.0
HKD2_k127_1586500_11 PFAM chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005062 272.0
HKD2_k127_1586500_12 Belongs to the phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000162 246.0
HKD2_k127_1586500_13 HutD - - - 0.00000000000000000000000000000000000000005357 158.0
HKD2_k127_1586500_14 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.0000000000000000000000000000000000000001375 153.0
HKD2_k127_1586500_15 Thioredoxin-like [2Fe-2S] ferredoxin - - - 0.000000000000000000000005104 103.0
HKD2_k127_1586500_16 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K18816 - 2.3.1.82 0.000000000000000000009751 93.0
HKD2_k127_1586500_17 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.00000000002243 66.0
HKD2_k127_1586500_18 - - - - 0.0000003772 53.0
HKD2_k127_1586500_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K01497,K02858,K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 1.781e-208 653.0
HKD2_k127_1586500_3 amino acid carrier protein K03310 - - 6.407e-198 628.0
HKD2_k127_1586500_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 535.0
HKD2_k127_1586500_5 stage II sporulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 530.0
HKD2_k127_1586500_6 Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 417.0
HKD2_k127_1586500_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 358.0
HKD2_k127_1586500_8 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 321.0
HKD2_k127_1586500_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002488 269.0
HKD2_k127_1607191_0 Bacterial regulatory protein, Fis family K06714 - - 1.176e-219 693.0
HKD2_k127_1607191_1 Belongs to the BCCT transporter (TC 2.A.15) family K02168,K05020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 612.0
HKD2_k127_1607191_2 Protein of unknown function (DUF445) - - - 0.0000000000000000000003506 101.0
HKD2_k127_161178_0 Initiates the rapid degradation of small, acid-soluble proteins during spore germination K06012 - 3.4.24.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 430.0
HKD2_k127_161178_1 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 383.0
HKD2_k127_161178_10 stage II sporulation protein P K06385 - - 0.000000000000000000000000000000000004731 152.0
HKD2_k127_161178_11 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.00000000000000000000000000000001792 130.0
HKD2_k127_161178_12 - - - - 0.00000000000000000000000000000001849 132.0
HKD2_k127_161178_13 Probable zinc-ribbon domain - - - 0.00000000000000000000000115 105.0
HKD2_k127_161178_14 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000001465 89.0
HKD2_k127_161178_15 - - - - 0.000000000000001015 81.0
HKD2_k127_161178_16 - - - - 0.00000000000104 70.0
HKD2_k127_161178_17 Small acid-soluble spore K06421 - - 0.0000000001309 65.0
HKD2_k127_161178_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 331.0
HKD2_k127_161178_3 PFAM Threonyl alanyl tRNA synthetase, SAD K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 338.0
HKD2_k127_161178_4 Polysaccharide biosynthesis C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 314.0
HKD2_k127_161178_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002021 246.0
HKD2_k127_161178_6 auxin efflux carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000000003828 227.0
HKD2_k127_161178_7 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000004488 224.0
HKD2_k127_161178_8 PFAM aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000004025 201.0
HKD2_k127_161178_9 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000001034 186.0
HKD2_k127_1615070_0 Anthranilate synthase component I, N terminal region K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008926 510.0
HKD2_k127_1615070_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 389.0
HKD2_k127_1615070_10 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000001424 67.0
HKD2_k127_1615070_11 beta-lactamase domain protein - - - 0.0000000000209 65.0
HKD2_k127_1615070_2 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 313.0
HKD2_k127_1615070_3 Glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 304.0
HKD2_k127_1615070_4 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000003371 228.0
HKD2_k127_1615070_5 Amino-transferase class IV K00826,K02619 - 2.6.1.42,4.1.3.38 0.0000000000000000000000000000000000000000000000000000004459 203.0
HKD2_k127_1615070_6 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000000000000000000000006098 196.0
HKD2_k127_1615070_7 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000002295 162.0
HKD2_k127_1615070_8 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.000000000000000000000000000000000003242 140.0
HKD2_k127_1615070_9 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000009893 107.0
HKD2_k127_1636320_0 This gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 587.0
HKD2_k127_1636320_1 Psort location Cytoplasmic, score 8.87 K05878 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 529.0
HKD2_k127_1636320_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 477.0
HKD2_k127_1636320_3 Belongs to the binding-protein-dependent transport system permease family K01997,K01998,K11961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 462.0
HKD2_k127_1636320_4 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 398.0
HKD2_k127_1636320_5 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 356.0
HKD2_k127_1636320_6 Dihydroxyacetone kinase, L subunit K05879 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 313.0
HKD2_k127_1636320_7 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001837 278.0
HKD2_k127_1636320_8 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007067 260.0
HKD2_k127_1637676_0 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005467 261.0
HKD2_k127_1637676_1 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000001578 241.0
HKD2_k127_1637676_2 decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000005662 119.0
HKD2_k127_1641410_0 ABC transporter transmembrane region K18890 - - 3.04e-224 709.0
HKD2_k127_1641410_1 ABC transporter transmembrane region K18889 - - 5.979e-200 638.0
HKD2_k127_1641410_2 2-nitropropane dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 388.0
HKD2_k127_1662710_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 5.756e-251 784.0
HKD2_k127_1662710_1 FtsX-like permease family K02004,K11632 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 566.0
HKD2_k127_1662710_10 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000001377 166.0
HKD2_k127_1662710_11 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.000000000000000000000000000000002946 131.0
HKD2_k127_1662710_2 Na Pi-cotransporter II-like protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 452.0
HKD2_k127_1662710_3 Psort location CytoplasmicMembrane, score K02003,K11635 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 393.0
HKD2_k127_1662710_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 365.0
HKD2_k127_1662710_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 359.0
HKD2_k127_1662710_6 UbiA prenyltransferase family K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 355.0
HKD2_k127_1662710_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 308.0
HKD2_k127_1662710_8 PFAM Lysine exporter protein (LYSE YGGA) K06895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006836 265.0
HKD2_k127_1662710_9 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000001432 237.0
HKD2_k127_1666604_0 von Willebrand factor, type A - - - 7.725e-292 922.0
HKD2_k127_1666604_1 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 433.0
HKD2_k127_1666604_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 299.0
HKD2_k127_1666604_3 protein some members contain a von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001328 247.0
HKD2_k127_1666604_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.00000000000000000000000000000000000000000000000000000002229 199.0
HKD2_k127_1666604_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000008313 160.0
HKD2_k127_1666604_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000001326 149.0
HKD2_k127_1666604_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000001933 87.0
HKD2_k127_1698286_0 amino acid - - - 2.25e-207 653.0
HKD2_k127_1698286_1 family 18 K06306 - - 8.195e-203 638.0
HKD2_k127_1698286_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 610.0
HKD2_k127_1698286_3 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 357.0
HKD2_k127_1698286_4 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 355.0
HKD2_k127_1698286_5 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 352.0
HKD2_k127_1753744_0 Deoxyguanosinetriphosphate triphosphohydrolase K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 443.0
HKD2_k127_1753744_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 400.0
HKD2_k127_1753744_2 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000504 136.0
HKD2_k127_1755667_0 Methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 357.0
HKD2_k127_1755667_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 324.0
HKD2_k127_1755667_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 311.0
HKD2_k127_1763029_0 phosphoribosylformylglycinamidine synthase K01952 - 6.3.5.3 9.429e-267 837.0
HKD2_k127_1763029_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 517.0
HKD2_k127_1763029_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 437.0
HKD2_k127_1763029_3 PFAM SAICAR synthetase K01756,K01923 - 4.3.2.2,6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 332.0
HKD2_k127_1763029_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000001243 219.0
HKD2_k127_1763029_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000009469 219.0
HKD2_k127_1763029_6 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000008286 176.0
HKD2_k127_1776119_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 523.0
HKD2_k127_1776119_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 434.0
HKD2_k127_1776119_2 amidohydrolase K05823 - 3.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 422.0
HKD2_k127_1776119_3 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate K00674,K05822 - 2.3.1.117,2.3.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 316.0
HKD2_k127_1776119_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 293.0
HKD2_k127_1776119_5 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000000000004817 220.0
HKD2_k127_1776119_6 Acetyltransferase (GNAT) domain K03824 - - 0.000000000000000000000000000000000000000164 156.0
HKD2_k127_1778141_0 Belongs to the glycosyl hydrolase 1 family - - - 4.84e-234 732.0
HKD2_k127_1778141_1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 K02755,K02756,K02757 - - 3.493e-196 626.0
HKD2_k127_1778141_2 transcriptional antiterminator K03488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 322.0
HKD2_k127_1778141_3 2-keto-3-deoxygluconate permease K02526 - - 0.000000000000000000000000158 108.0
HKD2_k127_1786846_0 Belongs to the ClpA ClpB family K03696 - - 1.632e-302 939.0
HKD2_k127_1786846_1 elongation factor g K02355 - - 2.252e-275 863.0
HKD2_k127_1786846_2 aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 438.0
HKD2_k127_1786846_3 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 369.0
HKD2_k127_1786846_4 PFAM UvrB uvrC K19411 - - 0.0000000000000000000000000000000000000000000000001963 182.0
HKD2_k127_1786846_5 Belongs to the CtsR family K03708 - - 0.000000000000000000000000000000000000000008887 158.0
HKD2_k127_1786846_6 - - - - 0.0000006247 53.0
HKD2_k127_1796700_0 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 452.0
HKD2_k127_1796700_1 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 427.0
HKD2_k127_1796700_2 Diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 335.0
HKD2_k127_1796700_3 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000002904 266.0
HKD2_k127_1817140_0 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 526.0
HKD2_k127_1817140_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000003032 246.0
HKD2_k127_1817140_2 pfam nudix - - - 0.000000000000000000000000000000000000000000000000000003502 199.0
HKD2_k127_1817140_3 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000001838 64.0
HKD2_k127_1817140_4 Peroxiredoxin K03386 - 1.11.1.15 0.0000000001235 63.0
HKD2_k127_1825661_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 492.0
HKD2_k127_1825661_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 381.0
HKD2_k127_1825661_2 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 297.0
HKD2_k127_1825661_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000001261 251.0
HKD2_k127_1825661_4 Divergent PAP2 family K09775 - - 0.00000000000000000000000000000000000000000000000001238 183.0
HKD2_k127_1825661_5 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000000000000000000000003767 173.0
HKD2_k127_1825661_6 Stage III sporulation protein AG K06396 - - 0.00000000000000000000000000000000422 136.0
HKD2_k127_1825661_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000212 131.0
HKD2_k127_1825661_8 SpoIIIAH-like protein K06397 - - 0.000000000000000006792 91.0
HKD2_k127_1825661_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000001112 64.0
HKD2_k127_186858_0 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 1.396e-209 670.0
HKD2_k127_186858_1 Flagellar Assembly Protein A K09749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 436.0
HKD2_k127_186858_10 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000002109 239.0
HKD2_k127_186858_11 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000007209 216.0
HKD2_k127_186858_12 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000938 203.0
HKD2_k127_186858_13 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000000000003584 163.0
HKD2_k127_186858_14 periplasmic solute-binding protein - - - 0.00000004037 61.0
HKD2_k127_186858_15 - - - - 0.0000001369 60.0
HKD2_k127_186858_16 PFAM Type IV pilus assembly PilZ - - - 0.00002496 49.0
HKD2_k127_186858_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 387.0
HKD2_k127_186858_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 366.0
HKD2_k127_186858_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 351.0
HKD2_k127_186858_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 319.0
HKD2_k127_186858_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 318.0
HKD2_k127_186858_7 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005308 276.0
HKD2_k127_186858_8 chemotaxis protein K03410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005046 254.0
HKD2_k127_186858_9 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000001163 239.0
HKD2_k127_1869188_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1515.0
HKD2_k127_1869188_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134,K00150,K03340 - 1.2.1.12,1.2.1.59,1.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 529.0
HKD2_k127_1869188_2 Protein of unknown function (DUF3810) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 316.0
HKD2_k127_1869188_3 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 293.0
HKD2_k127_1869188_4 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000005297 233.0
HKD2_k127_1869188_5 PFAM Iron only hydrogenase large subunit, C-terminal domain - - - 0.00001126 49.0
HKD2_k127_188183_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.194e-285 886.0
HKD2_k127_188183_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.454e-224 698.0
HKD2_k127_188183_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 499.0
HKD2_k127_188183_3 ATP synthase (C/AC39) subunit K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 303.0
HKD2_k127_188183_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 286.0
HKD2_k127_188183_5 ATP synthase subunit C K02124 - - 0.0000000000000000000000000000000000000000000000001917 181.0
HKD2_k127_188183_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000000000000000000009873 160.0
HKD2_k127_188183_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000000000000000009994 132.0
HKD2_k127_188183_8 DNA polymerase K02347 - - 0.0002033 46.0
HKD2_k127_1887351_0 Domain of unknown function (DUF4914) - - - 0.0 1140.0
HKD2_k127_1887351_1 Oligopeptidase F - - - 3.301e-306 947.0
HKD2_k127_1887351_10 Dihydroxyacetone kinase, L subunit K05879 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000000000000000000000001791 260.0
HKD2_k127_1887351_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000349 248.0
HKD2_k127_1887351_12 COG2206 HD-GYP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001512 239.0
HKD2_k127_1887351_13 - - - - 0.000000000000000000000000000000000000000000000000000000001374 206.0
HKD2_k127_1887351_14 FMN binding - - - 0.000000000000000000000000000000000000000000000000000007272 193.0
HKD2_k127_1887351_15 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000003924 181.0
HKD2_k127_1887351_16 dihydroxyacetone kinase, phosphotransfer subunit K05881 - 2.7.1.121 0.00000000000000000000000000000000000000007329 154.0
HKD2_k127_1887351_17 TPM domain K06872 - - 0.00000000000000000000000000002706 126.0
HKD2_k127_1887351_18 PFAM FMN-binding domain - - - 0.0000000000000000000000000006171 117.0
HKD2_k127_1887351_19 Phosphocarrier protein hpr K11189 - - 0.0000000000000000000008901 98.0
HKD2_k127_1887351_2 Glycine D-amino acid oxidase (deaminating) - - - 1.194e-253 791.0
HKD2_k127_1887351_3 lipoprotein YddW precursor K01189 - - - 8.357e-244 767.0
HKD2_k127_1887351_4 DAK1 domain protein K05878 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 544.0
HKD2_k127_1887351_5 Ser Thr phosphatase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 533.0
HKD2_k127_1887351_6 Oxidoreductase family, C-terminal alpha/beta domain K16044 - 1.1.1.371 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 435.0
HKD2_k127_1887351_7 FtsX-like permease family K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 361.0
HKD2_k127_1887351_8 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 323.0
HKD2_k127_1887351_9 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 314.0
HKD2_k127_1893822_0 Extracellular solute-binding protein, family 5 K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 417.0
HKD2_k127_1893822_1 Stage V sporulation protein B K06409 - - 0.0000000000000000000000000000000000000000000000000000002661 209.0
HKD2_k127_1893822_2 O-Antigen ligase K18814 - - 0.00000000000000000000000000000000981 141.0
HKD2_k127_190080_0 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 390.0
HKD2_k127_190080_1 PrpF protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 381.0
HKD2_k127_190080_2 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 342.0
HKD2_k127_190080_3 Dehydrogenase K19955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008531 284.0
HKD2_k127_190080_4 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001353 264.0
HKD2_k127_190080_5 MerR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003723 259.0
HKD2_k127_190080_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000001762 145.0
HKD2_k127_190080_7 Dehydrogenase K19955 - - 0.000000000000000004437 84.0
HKD2_k127_190080_8 Putative diguanylate phosphodiesterase - - - 0.0003504 43.0
HKD2_k127_191344_0 ABC transporter, ATP-binding protein K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 525.0
HKD2_k127_191344_1 Belongs to the ABC transporter superfamily K15583 - - 0.00000000136 59.0
HKD2_k127_1946527_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 4.78e-199 627.0
HKD2_k127_1946527_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 596.0
HKD2_k127_1946527_2 Putative nucleotide-binding of sugar-metabolising enzyme K22129 - 2.7.1.219,2.7.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 550.0
HKD2_k127_1946527_3 DEAD DEAH box helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 513.0
HKD2_k127_1946527_4 DNA topoisomerase III K03169 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 467.0
HKD2_k127_1946527_5 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 429.0
HKD2_k127_1946527_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 445.0
HKD2_k127_1946527_7 GPR1/FUN34/yaaH family K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 320.0
HKD2_k127_1946527_8 Transcriptional regulator DeoR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001066 279.0
HKD2_k127_1946527_9 2Fe-2S -binding domain - - - 0.000000000000000000001286 95.0
HKD2_k127_1953871_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1 3.53e-220 687.0
HKD2_k127_1953871_1 Phosphate acetyl/butaryl transferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 581.0
HKD2_k127_1953871_2 HIGH Nucleotidyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 397.0
HKD2_k127_1953871_3 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003214 255.0
HKD2_k127_1969654_0 PTS system, glucose-like IIB K02790,K02791 - 2.7.1.199,2.7.1.208 5.423e-239 748.0
HKD2_k127_1969654_1 Family 4 glycosyl hydrolase C-terminal domain K01222,K01232 - 3.2.1.122,3.2.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 315.0
HKD2_k127_1972629_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 427.0
HKD2_k127_1972629_1 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 360.0
HKD2_k127_1972629_2 PFAM helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000000000000000001913 187.0
HKD2_k127_1972629_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000006479 101.0
HKD2_k127_20115_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 590.0
HKD2_k127_20115_1 Psort location CytoplasmicMembrane, score 10.00 K02824 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 567.0
HKD2_k127_20115_10 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 342.0
HKD2_k127_20115_11 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 291.0
HKD2_k127_20115_12 spore cortex-lytic enzyme K01449 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000002596 265.0
HKD2_k127_20115_13 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000281 252.0
HKD2_k127_20115_14 PFAM Bacterial regulatory proteins, gntR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001653 239.0
HKD2_k127_20115_15 PFAM spore germination K06296,K06311 - - 0.000000000000000000000000000000000000000000000000000000000000222 226.0
HKD2_k127_20115_16 stage II sporulation protein R K06387 - - 0.00000000000000000000000000000000000000000000000000000000002378 213.0
HKD2_k127_20115_17 Spore germination B3/ GerAC like, C-terminal K06297 - - 0.00000000000000000000000000000000000000000000000001417 194.0
HKD2_k127_20115_18 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000002608 104.0
HKD2_k127_20115_19 Domain of unknown function (DUF1934) - - - 0.00000000000000000000009165 103.0
HKD2_k127_20115_2 Dehydrogenase K18012 - 1.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 550.0
HKD2_k127_20115_20 Small, acid-soluble spore proteins, alpha/beta type K06423 - - 0.0000000000000000007523 87.0
HKD2_k127_20115_3 GerA spore germination protein K06310 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 556.0
HKD2_k127_20115_4 Bacterial regulatory protein, Fis family K06714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 545.0
HKD2_k127_20115_5 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 482.0
HKD2_k127_20115_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 428.0
HKD2_k127_20115_7 Chemotaxis protein CheV K03407,K03415 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 422.0
HKD2_k127_20115_8 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 342.0
HKD2_k127_20115_9 germination protein YpeB K06313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 339.0
HKD2_k127_2015966_0 response regulator K07720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 516.0
HKD2_k127_2015966_1 Histidine kinase K07718 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003569 256.0
HKD2_k127_2023091_0 Alanine racemase, N-terminal domain K21898 - 5.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 382.0
HKD2_k127_2023091_1 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 334.0
HKD2_k127_2023091_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000006753 212.0
HKD2_k127_2023091_3 PBP superfamily domain K02040 - - 0.000000001455 62.0
HKD2_k127_203610_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 531.0
HKD2_k127_203610_1 PFAM RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 478.0
HKD2_k127_203610_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 377.0
HKD2_k127_203610_3 RNA polymerase sigma factor, sigma-70 family K03091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 336.0
HKD2_k127_203610_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 336.0
HKD2_k127_203610_5 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) K11145 - - 0.000000000000000000000000000000000000000002786 160.0
HKD2_k127_203610_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000345 125.0
HKD2_k127_2051474_0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 383.0
HKD2_k127_2051474_1 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000000000000000000000000000000000000000000001639 227.0
HKD2_k127_2051474_2 Nudix hydrolase - - - 0.000000000000000000000000000000000000001262 158.0
HKD2_k127_2051474_3 Phosphotransferase enzyme family - - - 0.00000000000000000006829 100.0
HKD2_k127_2051474_4 WD40-like Beta Propeller Repeat K03641 - - 0.00000000239 62.0
HKD2_k127_2051474_5 Domain of unknown function (DUF2935) - - - 0.000008405 57.0
HKD2_k127_211424_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.148e-259 809.0
HKD2_k127_211424_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 324.0
HKD2_k127_211424_10 - - - - 0.0006441 47.0
HKD2_k127_211424_2 endonuclease III K00567,K01247 - 2.1.1.63,3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 313.0
HKD2_k127_211424_3 transcriptional regulator K21903 - - 0.0000000000000000000000000000000000000000000000000000000007145 203.0
HKD2_k127_211424_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000004069 154.0
HKD2_k127_211424_5 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000005538 145.0
HKD2_k127_211424_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000001123 146.0
HKD2_k127_211424_7 SdpI/YhfL protein family - - - 0.00000000000000000000000000000005802 128.0
HKD2_k127_211424_8 TIGRFAM DNA binding domain, excisionase family - - - 0.0000000000000000000001656 98.0
HKD2_k127_211424_9 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.00000000001858 68.0
HKD2_k127_219011_0 Peptidase M16 K06972 - - 2.046e-218 693.0
HKD2_k127_219011_1 malic enzyme K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 486.0
HKD2_k127_219011_2 Cobalamin (Vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 402.0
HKD2_k127_219011_3 ABC-type cobalt transport system ATPase component K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 370.0
HKD2_k127_219011_4 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 302.0
HKD2_k127_219011_5 PFAM PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 302.0
HKD2_k127_219011_6 Cobalt ABC transporter, permease protein CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000904 280.0
HKD2_k127_2198161_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 5.411e-254 794.0
HKD2_k127_2198161_1 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 330.0
HKD2_k127_2198161_2 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000001419 149.0
HKD2_k127_2198161_3 Bacterial regulatory protein, Fis family K06714 - - 0.000000000000000000000000003725 113.0
HKD2_k127_2198161_4 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.00000000000000000000000001042 114.0
HKD2_k127_2198161_5 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000001024 94.0
HKD2_k127_2287910_0 Gluconate K03299 - - 7.478e-209 657.0
HKD2_k127_2287910_1 Pyridoxal-phosphate dependent enzyme - - - 5.442e-208 651.0
HKD2_k127_2287910_2 dehydrogenase complex catalyzes the overall conversion of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 411.0
HKD2_k127_2287910_3 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000006565 184.0
HKD2_k127_233476_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 405.0
HKD2_k127_233476_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 320.0
HKD2_k127_233476_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000001076 165.0
HKD2_k127_233476_3 HlyD family secretion protein K02005 - - 0.0000003194 55.0
HKD2_k127_2347043_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1097.0
HKD2_k127_2347043_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 368.0
HKD2_k127_2347043_2 SMART Metal-dependent phosphohydrolase, HD region - - - 0.0000000000000000000000000000000000000000000000000003566 198.0
HKD2_k127_2374354_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000107 263.0
HKD2_k127_2374354_1 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000003347 113.0
HKD2_k127_2430277_0 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 574.0
HKD2_k127_2430277_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000007996 94.0
HKD2_k127_2481962_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 519.0
HKD2_k127_2481962_1 Glycosyl hydrolases family 18 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 370.0
HKD2_k127_2481962_10 CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000003552 143.0
HKD2_k127_2481962_11 membrane transporter protein K07090 - - 0.000000000000000000000000000000000005771 140.0
HKD2_k127_2481962_12 - - - - 0.00000000000000000042 96.0
HKD2_k127_2481962_13 Domain of unknown function (DUF4349) - - - 0.00000000000000001402 93.0
HKD2_k127_2481962_15 Uracil-DNA glycosylase - - - 0.00000000000005213 74.0
HKD2_k127_2481962_16 EamA-like transporter family - - - 0.0003186 52.0
HKD2_k127_2481962_2 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 311.0
HKD2_k127_2481962_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 295.0
HKD2_k127_2481962_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000001595 219.0
HKD2_k127_2481962_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000001666 203.0
HKD2_k127_2481962_6 - - - - 0.0000000000000000000000000000000000000000000000000009837 187.0
HKD2_k127_2481962_7 Exonuclease, RNase T and DNA polymerase III - - - 0.00000000000000000000000000000000000000000000006948 175.0
HKD2_k127_2481962_8 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000181 155.0
HKD2_k127_2572764_0 Histidine kinase K11623 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 492.0
HKD2_k127_2572764_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002202 243.0
HKD2_k127_2610410_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.691e-206 646.0
HKD2_k127_2610410_1 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 550.0
HKD2_k127_2610410_10 sporulation protein - - - 0.00000000000000000000000000000000000000000000000002212 184.0
HKD2_k127_2610410_11 peptidase - - - 0.000000000000000000000000000000000000000003164 164.0
HKD2_k127_2610410_12 Stage III sporulation protein D K06283 - - 0.00000000000000000000000000000000006494 134.0
HKD2_k127_2610410_13 TATA-box binding - - - 0.00000000000000000000000000008909 126.0
HKD2_k127_2610410_14 - - - - 0.00000000000000000000000227 104.0
HKD2_k127_2610410_15 PFAM Flagellar protein FlgJ-like K02395 - - 0.0000000000000007111 81.0
HKD2_k127_2610410_2 MreB/Mbl protein K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 509.0
HKD2_k127_2610410_3 3-oxoacid CoA-transferase, B subunit K01035 - 2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 327.0
HKD2_k127_2610410_4 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 330.0
HKD2_k127_2610410_5 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01034 - 2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 322.0
HKD2_k127_2610410_6 flagellar basal body K02390,K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 308.0
HKD2_k127_2610410_7 TIGRFAM stage II sporulation protein D K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 292.0
HKD2_k127_2610410_8 basal body rod protein K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000001033 241.0
HKD2_k127_2610410_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000008622 232.0
HKD2_k127_2626987_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1467.0
HKD2_k127_2626987_1 Belongs to the UPF0371 family - - - 5.246e-245 759.0
HKD2_k127_2626987_2 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 581.0
HKD2_k127_2626987_3 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 320.0
HKD2_k127_2626987_4 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000007305 170.0
HKD2_k127_2626987_5 Belongs to the UPF0371 family - - - 0.00000000000000000000000000000000005888 134.0
HKD2_k127_2635923_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 606.0
HKD2_k127_2635923_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000005481 216.0
HKD2_k127_2635923_2 Molybdopterin oxidoreductase Fe4S4 domain K00123,K00367,K00372,K08356 - 1.17.1.9,1.20.2.1,1.20.9.1,1.7.7.2 0.00000000002042 64.0
HKD2_k127_2639981_0 Chemoreceptor zinc-binding domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 378.0
HKD2_k127_2639981_1 Belongs to the nlpA lipoprotein family K02073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 333.0
HKD2_k127_2639981_2 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system K02071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001922 279.0
HKD2_k127_2639981_3 ABC transporter permease K02072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002164 250.0
HKD2_k127_2639981_4 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000004262 166.0
HKD2_k127_2639981_5 - - - - 0.0000004944 52.0
HKD2_k127_26586_0 Sporulation protein YyaC - - - 0.000000000000000000000000000000000000000000000000000000000007908 213.0
HKD2_k127_26586_1 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000000000000000000000000000215 201.0
HKD2_k127_26586_2 mechanosensitive ion channel K22044 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000001638 158.0
HKD2_k127_26586_3 Protein of unknown function (DUF2089) - - - 0.0000000000000000000000000000000000001315 145.0
HKD2_k127_26586_4 Putative adhesin - - - 0.0000000000000000000000000000000000007885 154.0
HKD2_k127_26586_5 - - - - 0.000000000000000000007952 100.0
HKD2_k127_26586_6 Colicin V production protein K03558 - - 0.000000000001886 75.0
HKD2_k127_26586_7 - - - - 0.00000000001013 76.0
HKD2_k127_2690066_0 ABC-type sugar transport system, ATPase component K10441 - 3.6.3.17 5.375e-228 715.0
HKD2_k127_2690066_1 AP endonuclease family 2 C terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 600.0
HKD2_k127_2690066_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 481.0
HKD2_k127_2690066_3 ABC-type sugar transport system, periplasmic K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 477.0
HKD2_k127_2690066_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000002368 158.0
HKD2_k127_2743448_0 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 6.31e-290 899.0
HKD2_k127_2743448_1 FAD dependent oxidoreductase - - - 2.407e-237 737.0
HKD2_k127_2743448_2 membrane - - - 8.523e-222 694.0
HKD2_k127_2743448_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 358.0
HKD2_k127_2743448_4 Domain of unknown function (DUF1905) - - - 0.000000000000000000000000000000000000000001231 161.0
HKD2_k127_2743448_5 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.0000000000000000000000000003377 120.0
HKD2_k127_2743448_6 NDK K00940 - 2.7.4.6 0.00000000000000007291 82.0
HKD2_k127_2743448_7 Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000003609 79.0
HKD2_k127_2743448_8 Histidine kinase - - - 0.000000000000003447 76.0
HKD2_k127_2743448_9 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.0003164 47.0
HKD2_k127_2749051_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 1.845e-217 685.0
HKD2_k127_2749051_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 4.67e-215 674.0
HKD2_k127_2749051_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 452.0
HKD2_k127_2749051_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 337.0
HKD2_k127_2749051_4 Sam-dependent methyltransferase K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000000001737 187.0
HKD2_k127_2749051_5 Helix-turn-helix domain protein - - - 0.00000000000000000009824 102.0
HKD2_k127_2749051_6 Tautomerase enzyme - - - 0.0000006938 56.0
HKD2_k127_2749051_7 pyrroloquinoline quinone binding - - - 0.000004338 58.0
HKD2_k127_2781511_0 flavodoxin nitric oxide synthase K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0010181,GO:0016491,GO:0016651,GO:0016661,GO:0016662,GO:0016966,GO:0022900,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0050664,GO:0055114,GO:0072593,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.3.4 2.478e-269 844.0
HKD2_k127_2781511_1 UDP-galactopyranose mutase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 540.0
HKD2_k127_2781511_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000001285 241.0
HKD2_k127_2787005_0 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 529.0
HKD2_k127_2787005_1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 406.0
HKD2_k127_2787005_2 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000000000000000000000000000000001041 236.0
HKD2_k127_2787005_3 Chaperone for flagella basal body P-ring formation K02279 - - 0.000000000000000000000000000000000000000001205 166.0
HKD2_k127_2787005_4 TadE-like protein - - - 0.000000000000000000000004222 106.0
HKD2_k127_2787005_5 Flp Fap pilin component K02651 - - 0.000001773 51.0
HKD2_k127_2820032_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 5.756e-270 843.0
HKD2_k127_2820032_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 499.0
HKD2_k127_2820032_10 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000001079 268.0
HKD2_k127_2820032_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003129 278.0
HKD2_k127_2820032_12 60Kd inner membrane protein K03217 - - 0.00000000000000000000000000000000000000000000000000000000000002675 220.0
HKD2_k127_2820032_13 R3H domain protein K06346 - - 0.00000000000000000000000000000000000000000000000000000000000006069 220.0
HKD2_k127_2820032_14 Protein of unknown function (DUF4446) - - - 0.0000000000000000000000000000000003531 138.0
HKD2_k127_2820032_15 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000002035 119.0
HKD2_k127_2820032_16 Uncharacterised protein family (UPF0180) - - - 0.000000005254 61.0
HKD2_k127_2820032_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 501.0
HKD2_k127_2820032_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 473.0
HKD2_k127_2820032_4 sporulation initiation inhibitor protein Soj K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 391.0
HKD2_k127_2820032_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 387.0
HKD2_k127_2820032_6 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 377.0
HKD2_k127_2820032_7 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 317.0
HKD2_k127_2820032_8 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 314.0
HKD2_k127_2820032_9 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009978 283.0
HKD2_k127_2823202_0 PFAM sigma-54 factor interaction domain-containing protein - - - 9.761e-247 773.0
HKD2_k127_2823202_1 Oxidoreductase K07137 - - 1.151e-197 629.0
HKD2_k127_2823202_10 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.00000000000000000000000000000002642 126.0
HKD2_k127_2823202_2 Belongs to the acetokinase family K00929 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761 2.7.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 569.0
HKD2_k127_2823202_3 pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 524.0
HKD2_k127_2823202_4 Belongs to the acetokinase family K00929 - 2.7.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 509.0
HKD2_k127_2823202_5 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 424.0
HKD2_k127_2823202_6 phosphate butyryltransferase K00634 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747,GO:0050182 2.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 402.0
HKD2_k127_2823202_7 bacterial-type flagellum organization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005204 275.0
HKD2_k127_2823202_8 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001309 251.0
HKD2_k127_2823202_9 PFAM YbbR family protein - - - 0.0000000000000000000000000000000000000000000000002676 191.0
HKD2_k127_2828303_0 peptidase K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005783 276.0
HKD2_k127_2828303_1 Type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000003651 224.0
HKD2_k127_2828303_2 PFAM Bacterial Ig-like domain (group 2) - - - 0.00000000000000000000000000000000000000000000000004639 188.0
HKD2_k127_2828303_3 - K02664 - - 0.000000000000000000000000000000000001541 154.0
HKD2_k127_2828303_4 Fimbrial assembly protein (PilN) K02663 - - 0.000000000007128 73.0
HKD2_k127_2834435_0 YycH protein - - - 0.0000000000000000000001491 112.0
HKD2_k127_2834435_1 YycH protein - - - 0.000000000001367 74.0
HKD2_k127_2841902_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 608.0
HKD2_k127_2841902_1 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002311 264.0
HKD2_k127_2841902_2 Acetyltransferase, gnat family - - - 0.0000000000000000000000000000000000000000000000000005275 184.0
HKD2_k127_2841902_3 FAD dependent oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000004715 107.0
HKD2_k127_2841902_4 Radical SAM - - - 0.0000000000008461 70.0
HKD2_k127_2877174_0 Carbohydrate-binding domain-containing protein Cthe_2159 - GO:0001871,GO:0003674,GO:0005488,GO:0005509,GO:0030246,GO:0030247,GO:0030248,GO:0043167,GO:0043169,GO:0046872,GO:0048028,GO:2001062 - 1.001e-226 721.0
HKD2_k127_2877174_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009989 515.0
HKD2_k127_2877174_2 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 362.0
HKD2_k127_2877174_3 VTC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 346.0
HKD2_k127_2877174_4 Cell division protein FtsZ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 289.0
HKD2_k127_2877174_5 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000006072 192.0
HKD2_k127_2877174_6 chemotaxis protein K03406 - - 0.00000000000000000000001961 103.0
HKD2_k127_2882325_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 482.0
HKD2_k127_2882325_1 Dienelactone hydrolase family - - - 0.000000000000000000000000000000004016 142.0
HKD2_k127_2882325_2 Penicillin binding protein transpeptidase domain K17838 - 3.5.2.6 0.0000000001092 73.0
HKD2_k127_2882325_3 endonuclease exonuclease phosphatase family protein - - - 0.0000001593 55.0
HKD2_k127_2897807_0 Aldehyde ferredoxin K03738 - 1.2.7.5 0.0 1201.0
HKD2_k127_2897807_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 568.0
HKD2_k127_2897807_10 thiamine biosynthesis protein ThiS K03154 - - 0.00000000000000000000003071 100.0
HKD2_k127_2897807_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 499.0
HKD2_k127_2897807_3 PFAM Glycosyl transferase, group 1 K06338,K12995 - 2.4.1.348 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 476.0
HKD2_k127_2897807_4 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 437.0
HKD2_k127_2897807_5 coat protein K06337 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 399.0
HKD2_k127_2897807_6 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 374.0
HKD2_k127_2897807_7 spore coat protein, CotS K06331 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 361.0
HKD2_k127_2897807_8 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000001667 181.0
HKD2_k127_2897807_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000008864 134.0
HKD2_k127_290421_0 hydrolase, family 3 K01207 - 3.2.1.52 3.005e-255 795.0
HKD2_k127_290421_1 Branched-chain amino acid transport system / permease component K10440 - - 0.00000000000000000000000000000000000000000000006556 176.0
HKD2_k127_2914189_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.103e-308 967.0
HKD2_k127_2914189_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 579.0
HKD2_k127_2914189_2 Metallo-beta-lactamase domain protein K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 565.0
HKD2_k127_2914189_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 488.0
HKD2_k127_2914189_4 Spore coat protein - - - 0.00000000000000000000000000000000000000000134 163.0
HKD2_k127_2914189_5 - - - - 0.000000000000000000000000000007969 126.0
HKD2_k127_2914625_0 DNA polymerase III, alpha subunit K02337,K14162 - 2.7.7.7 0.0 1020.0
HKD2_k127_2914625_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.98e-226 715.0
HKD2_k127_2914625_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 515.0
HKD2_k127_2914625_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 484.0
HKD2_k127_2914625_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 442.0
HKD2_k127_2914625_5 peptidase M29 K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 336.0
HKD2_k127_2914625_6 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000004053 159.0
HKD2_k127_2914625_7 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.00000000000000000000000000000004597 131.0
HKD2_k127_2914625_8 - - - - 0.0000000000000000002832 89.0
HKD2_k127_2914625_9 PFAM NADPH-dependent FMN reductase - - - 0.000000000002232 69.0
HKD2_k127_2929214_0 beta-lactamase K01286 - 3.4.16.4 1.949e-208 654.0
HKD2_k127_2929214_1 Calcineurin-like phosphoesterase superfamily domain K01090 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 355.0
HKD2_k127_2929214_10 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000001177 209.0
HKD2_k127_2929214_11 GNAT acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000004963 199.0
HKD2_k127_2929214_12 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000005542 185.0
HKD2_k127_2929214_13 - - - - 0.0000000000000000000000000001177 121.0
HKD2_k127_2929214_14 methyltransferase K21459 - 2.1.1.301 0.0000000000000000000000000008939 122.0
HKD2_k127_2929214_15 GrpB protein - - - 0.000000000000000000000001919 109.0
HKD2_k127_2929214_16 - - - - 0.0000000000003817 71.0
HKD2_k127_2929214_17 methyltransferase - - - 0.00006289 46.0
HKD2_k127_2929214_2 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 309.0
HKD2_k127_2929214_3 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 294.0
HKD2_k127_2929214_4 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000116 281.0
HKD2_k127_2929214_5 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001099 276.0
HKD2_k127_2929214_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003501 270.0
HKD2_k127_2929214_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000002047 221.0
HKD2_k127_2929214_8 GCN5 family acetyltransferase K22477 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000005407 207.0
HKD2_k127_2929214_9 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000000000000000000000002987 207.0
HKD2_k127_2932070_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 4.798e-203 634.0
HKD2_k127_2932070_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 575.0
HKD2_k127_2932070_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 373.0
HKD2_k127_2932070_3 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000001402 78.0
HKD2_k127_295815_0 Alanine-glyoxylate amino-transferase K00812 - 2.6.1.1 4.18e-239 742.0
HKD2_k127_295815_1 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 346.0
HKD2_k127_295815_2 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 317.0
HKD2_k127_295815_3 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001486 262.0
HKD2_k127_29797_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.35e-294 919.0
HKD2_k127_29797_1 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 376.0
HKD2_k127_29797_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000002065 235.0
HKD2_k127_29797_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000242 130.0
HKD2_k127_3007187_0 import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 597.0
HKD2_k127_3007187_1 Belongs to the binding-protein-dependent transport system permease family K10440,K17214 - - 0.0000000000000000000000000000001553 130.0
HKD2_k127_3007187_2 ABC-type sugar transport system periplasmic component - - - 0.00000000002874 68.0
HKD2_k127_3017994_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1372.0
HKD2_k127_3017994_1 ABC-type nitrate sulfonate bicarbonate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 495.0
HKD2_k127_3017994_10 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001356 279.0
HKD2_k127_3017994_11 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008479 278.0
HKD2_k127_3017994_12 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000001436 194.0
HKD2_k127_3017994_13 Capsule synthesis protein K07282 - - 0.000000000000000000000000000000000000000000000000001649 190.0
HKD2_k127_3017994_14 Chemotaxis protein CheY K03413 - - 0.000000000000000000000000000000000000000006096 158.0
HKD2_k127_3017994_15 Membrane - - - 0.0000000000000000000000000002593 117.0
HKD2_k127_3017994_16 Thiamine-binding protein - - - 0.000000000000000002491 90.0
HKD2_k127_3017994_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 435.0
HKD2_k127_3017994_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 423.0
HKD2_k127_3017994_4 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 362.0
HKD2_k127_3017994_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 341.0
HKD2_k127_3017994_6 ABC-type nitrate sulfonate bicarbonate transport system, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 338.0
HKD2_k127_3017994_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 326.0
HKD2_k127_3017994_8 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 297.0
HKD2_k127_3017994_9 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 292.0
HKD2_k127_3022462_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 425.0
HKD2_k127_3022462_1 PFAM binding-protein-dependent transport systems inner membrane component K17319 - - 0.00000000000000000000000000000000000000000000000000000000000000000002217 240.0
HKD2_k127_3032404_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 9.008e-277 874.0
HKD2_k127_3032404_1 Phosphoribulokinase uridine kinase family K00876 - 2.7.1.48 7.113e-196 625.0
HKD2_k127_3032404_10 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000003356 235.0
HKD2_k127_3032404_11 UV-endonuclease UvdE K13281 - - 0.0000000000000000000000000000000000000000000000000000000000000000557 233.0
HKD2_k127_3032404_12 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000004514 226.0
HKD2_k127_3032404_13 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000005703 214.0
HKD2_k127_3032404_14 beta-lactamase superfamily III - - - 0.00000000000000000000000000000000000000000000000000000000127 209.0
HKD2_k127_3032404_15 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000002111 199.0
HKD2_k127_3032404_16 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000000000000000002366 165.0
HKD2_k127_3032404_17 protein ubiquitination K15503,K21440 - - 0.000000000000000000000000000000000000000904 160.0
HKD2_k127_3032404_18 Protein of unknown function (DUF2500) - - - 0.0000000000000000000000000002254 117.0
HKD2_k127_3032404_19 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) - - - 0.00000000000005012 80.0
HKD2_k127_3032404_2 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 534.0
HKD2_k127_3032404_20 SAM-dependent methyltransferase K06968 - 2.1.1.186 0.0000002118 59.0
HKD2_k127_3032404_21 Family of unknown function (DUF5362) - - - 0.0000008307 55.0
HKD2_k127_3032404_22 Spo0E like sporulation regulatory protein - - - 0.0000171 48.0
HKD2_k127_3032404_23 - - - - 0.0008007 44.0
HKD2_k127_3032404_3 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 445.0
HKD2_k127_3032404_4 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 446.0
HKD2_k127_3032404_5 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 427.0
HKD2_k127_3032404_6 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 406.0
HKD2_k127_3032404_7 aminopeptidase activity K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 371.0
HKD2_k127_3032404_8 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003129 265.0
HKD2_k127_3032404_9 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007195 268.0
HKD2_k127_304758_0 amino acid - - - 0.0 1034.0
HKD2_k127_304758_1 PHP domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 368.0
HKD2_k127_304758_2 - - - - 0.000000000000000000000000000000000000000000000000000000000003974 211.0
HKD2_k127_3091948_0 Protein of unknown function (DUF541) K09797 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 304.0
HKD2_k127_3091948_1 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000002022 159.0
HKD2_k127_3091948_2 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000008982 150.0
HKD2_k127_3091948_3 Cold shock protein K03704 - - 0.00000000000000000000000000000000003826 134.0
HKD2_k127_3091948_4 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000271 126.0
HKD2_k127_309912_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1125.0
HKD2_k127_309912_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 533.0
HKD2_k127_309912_10 Could be involved in septation K06412 - - 0.00000000000000000000000000000000000000001417 154.0
HKD2_k127_309912_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 522.0
HKD2_k127_309912_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 520.0
HKD2_k127_309912_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 442.0
HKD2_k127_309912_5 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 398.0
HKD2_k127_309912_6 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 328.0
HKD2_k127_309912_7 pur operon repressor K09685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008679 304.0
HKD2_k127_309912_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000001698 249.0
HKD2_k127_309912_9 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001324 235.0
HKD2_k127_3135174_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K18350 - 2.7.13.3 1.592e-206 647.0
HKD2_k127_3135174_1 Psort location Cytoplasmic, score 8.87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 568.0
HKD2_k127_3135174_10 Ubiquinone biosynthesis protein COQ7 - - - 0.000000000000000000000000000000000000000000000000004433 183.0
HKD2_k127_3135174_11 Integron-associated effector binding protein - - - 0.00000000000000000000000000000000000000000005498 165.0
HKD2_k127_3135174_12 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.0000000000000000000000000000002497 124.0
HKD2_k127_3135174_2 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 547.0
HKD2_k127_3135174_3 PFAM Response regulator receiver domain K18349 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 461.0
HKD2_k127_3135174_4 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 449.0
HKD2_k127_3135174_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 343.0
HKD2_k127_3135174_6 Diaminopropionate ammonia-lyase K01751 - 4.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 345.0
HKD2_k127_3135174_7 Phage tail protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 301.0
HKD2_k127_3135174_8 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003181 242.0
HKD2_k127_3135174_9 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000002282 207.0
HKD2_k127_3144303_0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K03483 - - 8.694e-200 642.0
HKD2_k127_3144303_1 PTS system mannitol-specific K02798,K02799,K02800 - 2.7.1.197 0.00000000000000000000000000000000000008148 143.0
HKD2_k127_3181124_0 phosphoenolpyruvate synthase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 526.0
HKD2_k127_3181124_1 COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 516.0
HKD2_k127_3181124_2 AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 509.0
HKD2_k127_3181124_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 404.0
HKD2_k127_3181124_4 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 375.0
HKD2_k127_3181124_5 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000003286 208.0
HKD2_k127_3181124_6 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000006541 184.0
HKD2_k127_3181124_7 Redoxin - - - 0.00000000000002369 74.0
HKD2_k127_3233599_0 Aminotransferase K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 488.0
HKD2_k127_3233599_1 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 427.0
HKD2_k127_3233599_2 Belongs to the bacterial solute-binding protein 3 family K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 309.0
HKD2_k127_3233599_3 PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.000000000000000000000000000000000000000000000000000000002725 202.0
HKD2_k127_3271954_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.981e-238 746.0
HKD2_k127_3271954_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 331.0
HKD2_k127_3271954_2 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004724 278.0
HKD2_k127_3271954_3 - - - - 0.000000000000000000000000000000000000000000000007411 181.0
HKD2_k127_3271954_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000002671 161.0
HKD2_k127_3271954_5 Peptidase family M28 K01258 - 3.4.11.4 0.000000000000000000000000000004316 123.0
HKD2_k127_3271954_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000006931 85.0
HKD2_k127_3356_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 336.0
HKD2_k127_3356_1 Protein of unknown function (DUF975) - - - 0.00000000000000000000000000000000000000000000000000000000007746 208.0
HKD2_k127_3356_2 HNH nucleases - - - 0.000000000421 66.0
HKD2_k127_3356_3 PrcB C-terminal - - - 0.00007976 50.0
HKD2_k127_3377958_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 8.666e-230 720.0
HKD2_k127_3377958_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 3.04e-215 683.0
HKD2_k127_3377958_10 acetyltransferase - - - 0.0000000000000000000000002274 109.0
HKD2_k127_3377958_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 377.0
HKD2_k127_3377958_3 response regulator, receiver K07770 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 334.0
HKD2_k127_3377958_4 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 311.0
HKD2_k127_3377958_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000473 209.0
HKD2_k127_3377958_6 Protein of unknown function (DUF402) K09145 - - 0.0000000000000000000000000000000000000000002404 164.0
HKD2_k127_3377958_7 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000002355 162.0
HKD2_k127_3377958_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000001334 156.0
HKD2_k127_3377958_9 VanZ like family - - - 0.00000000000000000000000003822 113.0
HKD2_k127_337896_0 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) K07862 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 590.0
HKD2_k127_337896_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000002787 208.0
HKD2_k127_337896_2 Restriction endonuclease K07448 - - 0.0000000000000000000000000000003652 130.0
HKD2_k127_3396952_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 541.0
HKD2_k127_3396952_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 532.0
HKD2_k127_3396952_10 Hydrolase, HD family - - - 0.000000000000000000000000000000000000000000000003158 179.0
HKD2_k127_3396952_11 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000000000003171 167.0
HKD2_k127_3396952_12 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000002145 146.0
HKD2_k127_3396952_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000006528 138.0
HKD2_k127_3396952_14 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000000000003431 133.0
HKD2_k127_3396952_15 RNA-binding protein K07574 - - 0.00000000000000000000000000008758 118.0
HKD2_k127_3396952_16 Cysteine protease Prp K07584 - - 0.000000000000000000000019 103.0
HKD2_k127_3396952_17 - - - - 0.0000000000000000007902 87.0
HKD2_k127_3396952_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 446.0
HKD2_k127_3396952_3 translation elongation factor K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 434.0
HKD2_k127_3396952_4 PFAM peptidase S11, D-alanyl-D-alanine carboxypeptidase K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 327.0
HKD2_k127_3396952_5 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001704 269.0
HKD2_k127_3396952_6 HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008059 248.0
HKD2_k127_3396952_7 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000001877 247.0
HKD2_k127_3396952_8 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005762 246.0
HKD2_k127_3396952_9 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000001608 176.0
HKD2_k127_3415202_0 hydrolase, family 3 K01207 - 3.2.1.52 9.665e-274 851.0
HKD2_k127_3415202_1 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 6.761e-197 625.0
HKD2_k127_3415202_2 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 435.0
HKD2_k127_3464840_0 NADH ubiquinone oxidoreductase K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 1.385e-313 968.0
HKD2_k127_3464840_1 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 9.267e-195 616.0
HKD2_k127_3464840_10 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000006018 200.0
HKD2_k127_3464840_11 Protein of unknown function (DUF3189) - - - 0.0000000000000000000000000000000000000000000000000000035 195.0
HKD2_k127_3464840_12 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000001621 195.0
HKD2_k127_3464840_13 Ferredoxin K17992 - 1.12.1.3 0.00000000000000000000000000000000000000000000000001334 182.0
HKD2_k127_3464840_14 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000002553 176.0
HKD2_k127_3464840_15 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000000000000006509 172.0
HKD2_k127_3464840_16 Part of a membrane complex involved in electron transport K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000005542 158.0
HKD2_k127_3464840_17 DRTGG domain - - - 0.000000000000000000000000000000000000003394 149.0
HKD2_k127_3464840_18 DRTGG domain - - - 0.0000000000000000000000000000000001792 134.0
HKD2_k127_3464840_19 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000002613 121.0
HKD2_k127_3464840_2 Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 448.0
HKD2_k127_3464840_20 Belongs to the binding-protein-dependent transport system permease family K10547 - - 0.000000000000000001406 85.0
HKD2_k127_3464840_21 Lysine exporter LysO - - - 0.0000000000003467 74.0
HKD2_k127_3464840_22 Domain of unknown function (DUF4321) - - - 0.000000004153 61.0
HKD2_k127_3464840_23 Belongs to the UPF0758 family K03630 - - 0.0000006789 51.0
HKD2_k127_3464840_3 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 434.0
HKD2_k127_3464840_4 NQR2, RnfD, RnfE family K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 411.0
HKD2_k127_3464840_5 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004857 274.0
HKD2_k127_3464840_6 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007096 262.0
HKD2_k127_3464840_7 Lysine exporter LysO - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002713 254.0
HKD2_k127_3464840_8 PHP domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000002284 251.0
HKD2_k127_3464840_9 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330,K22340 - 1.12.1.3,1.17.1.11,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000006848 213.0
HKD2_k127_3505146_0 conserved protein (DUF2174) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 320.0
HKD2_k127_3505146_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008286 270.0
HKD2_k127_3505146_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009326 243.0
HKD2_k127_3505146_3 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000004253 226.0
HKD2_k127_3505146_4 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000001025 228.0
HKD2_k127_3505146_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000007794 180.0
HKD2_k127_3505146_6 modulator of DNA gyrase K03568 - - 0.00000002972 57.0
HKD2_k127_360247_0 TRAP transporter, 4TM 12TM fusion protein - - - 3.213e-253 796.0
HKD2_k127_360247_1 ATPases associated with a variety of cellular activities K17215 - - 2.704e-248 773.0
HKD2_k127_360247_10 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 342.0
HKD2_k127_360247_11 PFAM ATP-binding region, ATPase domain protein K07717 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004047 283.0
HKD2_k127_360247_12 NlpC/P60 family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000004041 246.0
HKD2_k127_360247_13 YcbB domain K07719 - - 0.00000000000000000000000000000000000000000000000000000000000000000004866 241.0
HKD2_k127_360247_14 Carbohydrate kinase, FGGY K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000001283 212.0
HKD2_k127_360247_15 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000002697 210.0
HKD2_k127_360247_16 Domain of unknown function (DUF1850) - - - 0.000000000000006385 81.0
HKD2_k127_360247_2 Histidine kinase K07718 - 2.7.13.3 7.278e-223 704.0
HKD2_k127_360247_3 Bacterial extracellular solute-binding protein K02027 - - 2.651e-213 672.0
HKD2_k127_360247_4 Psort location Cytoplasmic, score K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 571.0
HKD2_k127_360247_5 response regulator receiver K07720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 539.0
HKD2_k127_360247_6 PFAM extracellular solute-binding protein, family 5 K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 524.0
HKD2_k127_360247_7 Belongs to the binding-protein-dependent transport system permease family K10440,K17214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 500.0
HKD2_k127_360247_8 PFAM periplasmic binding protein K10439,K17213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 498.0
HKD2_k127_360247_9 mandelate racemase muconate lactonizing K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 388.0
HKD2_k127_365863_0 Dehydrogenase K00100,K19955 GO:0003674,GO:0003824,GO:0004022,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - 1.877e-194 608.0
HKD2_k127_365863_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 599.0
HKD2_k127_365863_2 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 365.0
HKD2_k127_365863_4 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003893 255.0
HKD2_k127_365863_5 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000002885 56.0
HKD2_k127_3666415_0 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 357.0
HKD2_k127_3666415_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001931 256.0
HKD2_k127_3666415_2 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000001666 134.0
HKD2_k127_376151_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 291.0
HKD2_k127_376151_2 PFAM YbaK prolyl-tRNA synthetases associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001089 232.0
HKD2_k127_376151_3 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.00000000000000000307 85.0
HKD2_k127_377559_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 518.0
HKD2_k127_377559_1 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 394.0
HKD2_k127_377559_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 371.0
HKD2_k127_377559_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 329.0
HKD2_k127_377559_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000000000000004231 149.0
HKD2_k127_3823549_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.142e-305 947.0
HKD2_k127_3823549_1 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 466.0
HKD2_k127_3823549_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000009882 229.0
HKD2_k127_3823549_3 Yip1 domain - - - 0.0000000002485 67.0
HKD2_k127_3823549_4 CAAX protease self-immunity - - - 0.0000003719 60.0
HKD2_k127_3836496_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 9.012e-220 696.0
HKD2_k127_3836496_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 560.0
HKD2_k127_3837604_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 7.578e-227 722.0
HKD2_k127_3837604_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 562.0
HKD2_k127_3837604_2 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 445.0
HKD2_k127_3837604_3 response regulator receiver K07720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 348.0
HKD2_k127_3837604_4 MarR family - - - 0.00000000000000000000000000000000000000000000000000000001984 200.0
HKD2_k127_3837604_5 Diguanylate cyclase - - - 0.000000000000000000000000005969 114.0
HKD2_k127_3855778_0 Radical SAM K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 565.0
HKD2_k127_3855778_1 Thioredoxin reductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 316.0
HKD2_k127_3855778_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 298.0
HKD2_k127_3855778_3 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate K15024 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001236 267.0
HKD2_k127_3855778_4 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002379 240.0
HKD2_k127_3855778_5 Sporulation and spore germination K06298 - - 0.00000000000000000000000000000000000000000000000000000000000001592 226.0
HKD2_k127_3855778_6 PFAM Abortive infection protein K07052 - - 0.000000000000000000000000000000000000000000000000003415 194.0
HKD2_k127_3855778_7 TIGRFAM integral membrane protein TIGR01906 - - - 0.00000000000000000000000000000000000000001134 162.0
HKD2_k127_3855778_8 - - - - 0.000000000000003855 87.0
HKD2_k127_3860661_0 system, fructose subfamily, IIA component - - - 0.0 1044.0
HKD2_k127_3860661_1 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.158e-201 635.0
HKD2_k127_3860661_10 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003551 268.0
HKD2_k127_3860661_11 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000003985 183.0
HKD2_k127_3860661_12 phosphotransferase system K02759 - 2.7.1.196,2.7.1.205 0.0000000000000000000000000000000000914 136.0
HKD2_k127_3860661_13 system, Lactose K02760 - 2.7.1.196,2.7.1.205 0.000000000000000000000000000004776 123.0
HKD2_k127_3860661_14 ThiS family - - - 0.0000000000000000000002054 98.0
HKD2_k127_3860661_15 phosphocarrier protein HPr K02784,K11189 - - 0.0000000000000001203 82.0
HKD2_k127_3860661_2 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane K02761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 606.0
HKD2_k127_3860661_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 578.0
HKD2_k127_3860661_4 hmm pf05913 K09963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 527.0
HKD2_k127_3860661_5 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 421.0
HKD2_k127_3860661_6 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 369.0
HKD2_k127_3860661_7 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 340.0
HKD2_k127_3860661_8 UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 295.0
HKD2_k127_3860661_9 BCR, YitT family COG1284 K07149 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 295.0
HKD2_k127_3896036_0 SMART Metal-dependent phosphohydrolase, HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 349.0
HKD2_k127_3896036_1 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 318.0
HKD2_k127_3896036_2 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 310.0
HKD2_k127_3898222_0 Uncharacterized protein family UPF0029 - - - 0.00000000000000000000000000000000000000000000000000003442 194.0
HKD2_k127_3898222_1 - - - - 0.0000004624 60.0
HKD2_k127_3898222_2 - - - - 0.00006424 50.0
HKD2_k127_3936216_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K21577 - 1.21.4.2,1.21.4.3,1.21.4.4 9.305e-210 662.0
HKD2_k127_3936216_1 PFAM fatty acid synthesis plsX protein K21576 - 1.21.4.2,1.21.4.3,1.21.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 519.0
HKD2_k127_3936216_2 basic membrane K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 332.0
HKD2_k127_3936216_3 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000001656 109.0
HKD2_k127_393708_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 4.505e-241 753.0
HKD2_k127_393708_1 Glycosyl hydrolase family 65, N-terminal domain K05342 - 2.4.1.64 8.256e-241 765.0
HKD2_k127_393708_10 DNA polymerase alpha chain like domain K04486 - 3.1.3.15 0.000000000000000000000000000000000001761 142.0
HKD2_k127_393708_2 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 508.0
HKD2_k127_393708_3 Binding-protein-dependent transport system inner membrane component K02025,K10237,K15771 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 428.0
HKD2_k127_393708_4 Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 383.0
HKD2_k127_393708_5 Tryptophan transporter TrpP - - - 0.000000000000000000000000000000000000000000000000000000000000000001734 230.0
HKD2_k127_393708_6 Catalyzes the interconversion of beta-D-glucose 6-phosphate to beta-D-glucose 1-phosphate K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000000000000000000000001114 222.0
HKD2_k127_393708_7 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000006889 207.0
HKD2_k127_393708_8 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000006218 200.0
HKD2_k127_393708_9 ATP cob(I)alamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000001733 187.0
HKD2_k127_393885_0 peptidase K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000004744 254.0
HKD2_k127_393885_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.00000000000000000000000000000000000000000000000000000006926 198.0
HKD2_k127_393885_2 HAD superfamily (Subfamily IIIA) phosphatase K07015 - - 0.0000000000000000000000000000000000000000000000001595 181.0
HKD2_k127_393885_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000001986 176.0
HKD2_k127_393885_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000515 130.0
HKD2_k127_393885_5 PFAM Late competence development protein ComFB K02241 - - 0.000000000000000000000006742 103.0
HKD2_k127_3995021_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 2.213e-284 882.0
HKD2_k127_3995021_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 1.552e-231 730.0
HKD2_k127_3995021_2 Peptidase M16 K06972 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 422.0
HKD2_k127_3995021_3 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001839 234.0
HKD2_k127_3995021_4 - - - - 0.00000000000000000000000000000000002466 137.0
HKD2_k127_4000527_0 aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 599.0
HKD2_k127_4000527_1 Cell division protein FtsI penicillin-binding protein 2 K05364 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 541.0
HKD2_k127_4000527_2 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008088 477.0
HKD2_k127_4000527_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000006647 125.0
HKD2_k127_400565_0 domain protein - - - 9.104e-218 694.0
HKD2_k127_400565_1 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 4.04e-200 640.0
HKD2_k127_400565_10 Predicted membrane protein (DUF2232) - - - 0.000000000000000000003844 105.0
HKD2_k127_400565_2 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 611.0
HKD2_k127_400565_3 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000002198 171.0
HKD2_k127_400565_4 Single-stranded DNA-binding protein K03111 - - 0.000000000000000000000000000000000000000000003008 167.0
HKD2_k127_400565_5 Mechanosensitive ion channel K16052,K22044 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000009231 166.0
HKD2_k127_400565_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000001314 134.0
HKD2_k127_400565_7 MazG-like family - - - 0.0000000000000000000000000000001162 128.0
HKD2_k127_400565_8 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000001003 118.0
HKD2_k127_400565_9 Bacterial protein of unknown function (DUF951) - - - 0.000000000000000000000000001044 113.0
HKD2_k127_4034085_0 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 2.049e-280 898.0
HKD2_k127_4034085_1 Glycine/sarcosine/betaine reductase component B subunits K10671 - 1.21.4.2 1.489e-213 669.0
HKD2_k127_4034085_10 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000002521 121.0
HKD2_k127_4034085_11 Glycine reductase complex selenoprotein A K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0000000000000003292 78.0
HKD2_k127_4034085_2 glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 544.0
HKD2_k127_4034085_3 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 511.0
HKD2_k127_4034085_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 406.0
HKD2_k127_4034085_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000002901 241.0
HKD2_k127_4034085_6 In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0000000000000000000000000000000000000000004994 159.0
HKD2_k127_4034085_7 glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.000000000000000000000000000000000000001516 147.0
HKD2_k127_4034085_8 PFAM CheC domain protein K03409 - - 0.000000000000000000000000000000000001177 144.0
HKD2_k127_4034085_9 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000002258 138.0
HKD2_k127_404086_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 5.652e-288 889.0
HKD2_k127_404086_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 383.0
HKD2_k127_404086_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.000000000000000000000000000000000000000000000001418 175.0
HKD2_k127_404086_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000006224 63.0
HKD2_k127_4050392_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.0 1091.0
HKD2_k127_4050392_1 - - - - 0.000000000000000000000000009453 113.0
HKD2_k127_405049_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 474.0
HKD2_k127_405049_1 - - - - 0.000000000000000004201 88.0
HKD2_k127_405049_2 type II secretion system K02653 - - 0.000000000000000009299 84.0
HKD2_k127_405049_3 Pfam:N_methyl_2 - - - 0.0000000001426 68.0
HKD2_k127_405049_4 Domain of unknown function (DUF4860) - - - 0.000000007452 64.0
HKD2_k127_405049_5 - - - - 0.000000009771 65.0
HKD2_k127_4093021_0 Bacterial extracellular solute-binding protein K17318 - - 2.85e-255 796.0
HKD2_k127_4093021_1 Binding-protein-dependent transport system inner membrane component K17319 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 501.0
HKD2_k127_4093021_2 Binding-protein-dependent transport system inner membrane component K17320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 466.0
HKD2_k127_4093021_3 Methyltransferase domain - - - 0.0000000000000000000000000001413 114.0
HKD2_k127_4110133_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.31e-267 835.0
HKD2_k127_4110133_1 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 8.422e-236 733.0
HKD2_k127_4110133_10 ATP synthase subunit C K02124 - - 0.0000000000000000000000000000000005689 135.0
HKD2_k127_4110133_11 ATP synthase (F/14-kDa) subunit K02122 - - 0.000000000000000000000000000001501 124.0
HKD2_k127_4110133_12 COG1390 Archaeal vacuolar-type H -ATPase subunit E - - - 0.000000000000001217 85.0
HKD2_k127_4110133_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 2.968e-200 630.0
HKD2_k127_4110133_3 V-type ATPase 116kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009486 604.0
HKD2_k127_4110133_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 536.0
HKD2_k127_4110133_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 523.0
HKD2_k127_4110133_6 Pfam:DUF342 K09749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 456.0
HKD2_k127_4110133_7 ATP synthase (C/AC39) subunit K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 334.0
HKD2_k127_4110133_8 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 306.0
HKD2_k127_4110133_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007945 253.0
HKD2_k127_411562_0 cobalamin binding K17898 - 5.4.3.5 0.0 1298.0
HKD2_k127_411562_1 Pyridoxal-phosphate dependent enzyme K21400 - 2.3.1.263 2.874e-240 749.0
HKD2_k127_411562_2 MutL protein - - - 2.039e-218 684.0
HKD2_k127_411562_3 Dihydrodipicolinate reductase, N-terminus K21672 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047530,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 587.0
HKD2_k127_411562_4 Alanine racemase, N-terminal domain K21898 - 5.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 387.0
HKD2_k127_411562_5 D-ornithine 4,5-aminomutase alpha-subunit K17899 - 5.4.3.5 0.000000000000000000000000000000000000000000000000007235 182.0
HKD2_k127_411562_6 DNA polymerase alpha chain like domain K04486 - 3.1.3.15 0.0000000000000000000000000000000000000002771 154.0
HKD2_k127_411562_7 - K21399 GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 2.3.1.263 0.0000000000000000000000000000000000001483 143.0
HKD2_k127_411562_8 Alanine racemase, N-terminal domain K21898 - 5.1.1.12 0.000000000000000000000002068 104.0
HKD2_k127_4142681_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 541.0
HKD2_k127_4142681_1 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 410.0
HKD2_k127_4142681_10 Domain of unknown function (DUF4330) - - - 0.000000000000003413 82.0
HKD2_k127_4142681_11 Domain of unknown function (DUF4330) - - - 0.0000000000001384 77.0
HKD2_k127_4142681_2 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 359.0
HKD2_k127_4142681_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 293.0
HKD2_k127_4142681_4 Belongs to the glycosyl hydrolase 26 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004878 258.0
HKD2_k127_4142681_5 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000000000002184 234.0
HKD2_k127_4142681_6 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000007108 232.0
HKD2_k127_4142681_7 O-Antigen Polymerase K18814 - - 0.0000000000000000000000000000000000000000000000000000000000000004546 243.0
HKD2_k127_4142681_8 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000000000000000000000001496 197.0
HKD2_k127_4144304_0 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 488.0
HKD2_k127_4144304_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 411.0
HKD2_k127_4144304_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 370.0
HKD2_k127_4144304_3 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 351.0
HKD2_k127_4144304_4 Response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000101 287.0
HKD2_k127_4144304_5 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000286 278.0
HKD2_k127_4144304_6 PFAM extracellular solute-binding protein family 1 K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002897 272.0
HKD2_k127_4144304_7 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003229 253.0
HKD2_k127_4163190_0 ABC transporter K02056 - 3.6.3.17 2.95e-212 668.0
HKD2_k127_4163190_1 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 324.0
HKD2_k127_41846_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 521.0
HKD2_k127_41846_1 Phosphoglycerol transferase and related proteins,, alkaline phosphatase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 469.0
HKD2_k127_41846_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006074 275.0
HKD2_k127_41846_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000001395 78.0
HKD2_k127_41889_0 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate K15024 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 295.0
HKD2_k127_41889_1 NADPH-quinone reductase (modulator of drug activity B) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001314 277.0
HKD2_k127_41889_2 Domain of unknown function (DUF4342) - - - 0.000000000000000000000000000000000000001141 151.0
HKD2_k127_41889_4 AAA domain - - - 0.0000000000000000468 89.0
HKD2_k127_41889_5 - - - - 0.0006429 45.0
HKD2_k127_4200556_0 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 604.0
HKD2_k127_4200556_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 391.0
HKD2_k127_4200556_2 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000004469 69.0
HKD2_k127_4214855_0 Oligoendopeptidase, pepF M3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 466.0
HKD2_k127_4214855_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 343.0
HKD2_k127_4214855_10 - - - - 0.000001449 50.0
HKD2_k127_4214855_2 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000002449 270.0
HKD2_k127_4214855_3 Sporulation and spore germination K06298 - - 0.0000000000000000000000000000000000000000000000000000481 200.0
HKD2_k127_4214855_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000001303 174.0
HKD2_k127_4214855_5 Helix-turn-helix domain, rpiR family - - - 0.00000000000000000001018 97.0
HKD2_k127_4214855_8 - - - - 0.0000001722 53.0
HKD2_k127_4214855_9 - - - - 0.0000005545 54.0
HKD2_k127_4234066_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 479.0
HKD2_k127_4234066_1 Two component transcriptional regulator, winged helix family K02483,K18344 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 285.0
HKD2_k127_4234066_2 Spore germination protein K06296 - - 0.0000000000000000000000005708 109.0
HKD2_k127_4234066_3 Domain of Unknown Function (DUF326) - - - 0.0000000000000000000000009078 107.0
HKD2_k127_4234066_4 Heavy metal transport detoxification protein - - - 0.000000000000000000000005104 103.0
HKD2_k127_4234066_5 Domain of Unknown Function (DUF1540) - - - 0.0000000000000000000001471 97.0
HKD2_k127_4234066_6 - - - - 0.000007434 53.0
HKD2_k127_4234066_7 - - - - 0.00003024 47.0
HKD2_k127_425701_0 import. Responsible for energy coupling to the transport system K10548 - 3.6.3.17 6.63e-257 799.0
HKD2_k127_425701_1 Belongs to the binding-protein-dependent transport system permease family K10547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 563.0
HKD2_k127_425701_2 Periplasmic binding protein domain K10546 - - 0.000000000003912 66.0
HKD2_k127_4260264_0 Putative rRNA methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007493 244.0
HKD2_k127_4260264_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000004174 214.0
HKD2_k127_4260264_2 B3/4 domain - - - 0.0000000000000000000000000000000000000000000000000004853 185.0
HKD2_k127_4260264_3 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000002053 132.0
HKD2_k127_4260264_4 Flagellar hook-length control protein FliK - - - 0.000000000000000000001859 103.0
HKD2_k127_4260264_5 FlhB HrpN YscU SpaS Family K04061 - - 0.000000000000000000005188 94.0
HKD2_k127_428236_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 1.346e-228 716.0
HKD2_k127_428236_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 523.0
HKD2_k127_428236_2 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 480.0
HKD2_k127_428236_3 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 363.0
HKD2_k127_428236_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 297.0
HKD2_k127_428236_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002512 263.0
HKD2_k127_428236_6 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001407 243.0
HKD2_k127_428236_7 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000001552 221.0
HKD2_k127_428236_8 COG0346 LactoylglutaTHIone lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000000008724 203.0
HKD2_k127_428236_9 - - - - 0.00000000000000000000000000000000000000000006293 162.0
HKD2_k127_43403_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 465.0
HKD2_k127_43403_1 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 347.0
HKD2_k127_43403_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000002583 225.0
HKD2_k127_43403_3 Domain of unknown function (DUF4364) - - - 0.000000000000000000000000000000000000000002525 161.0
HKD2_k127_43403_4 Small, acid-soluble spore proteins, alpha/beta type - - - 0.0000000000000000000000002949 107.0
HKD2_k127_43403_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000004404 105.0
HKD2_k127_43403_6 - - - - 0.00000000002486 66.0
HKD2_k127_4355775_0 COG1264 Phosphotransferase system IIB components - - - 7.885e-268 836.0
HKD2_k127_4355775_1 Belongs to the glycosyl hydrolase 1 family K01223 - 3.2.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 479.0
HKD2_k127_4355775_2 antiterminator K03488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 436.0
HKD2_k127_4355775_3 tRNA 3'-trailer cleavage - - - 0.000000006378 60.0
HKD2_k127_4368750_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 506.0
HKD2_k127_4368750_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 331.0
HKD2_k127_4368750_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000007004 250.0
HKD2_k127_4368750_3 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000001708 158.0
HKD2_k127_4373781_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 9.983e-210 659.0
HKD2_k127_4373781_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 338.0
HKD2_k127_4373781_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 331.0
HKD2_k127_4373781_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000006041 131.0
HKD2_k127_4411087_0 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 482.0
HKD2_k127_4411087_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 328.0
HKD2_k127_4411087_2 O-methyltransferase - - - 0.00000000000001229 75.0
HKD2_k127_443695_0 TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 7.435e-216 672.0
HKD2_k127_443695_1 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 284.0
HKD2_k127_443695_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000001131 164.0
HKD2_k127_449067_0 S-layer homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003246 254.0
HKD2_k127_449067_1 - - - - 0.0000000000000000000000000000000000000000167 154.0
HKD2_k127_449067_2 COG NOG18757 non supervised orthologous group - - - 0.000000000000000000000000000000000000000414 150.0
HKD2_k127_453010_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 501.0
HKD2_k127_453010_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 367.0
HKD2_k127_453010_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000006187 166.0
HKD2_k127_4578818_0 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 437.0
HKD2_k127_4578818_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000004962 173.0
HKD2_k127_4578818_2 Spo0E like sporulation regulatory protein - - - 0.00001369 49.0
HKD2_k127_4613418_0 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 8.755e-197 628.0
HKD2_k127_4613418_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 598.0
HKD2_k127_4613418_2 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000699 252.0
HKD2_k127_4613418_3 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000006066 213.0
HKD2_k127_4613418_4 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000001683 165.0
HKD2_k127_4613418_5 Rubrerythrin - - - 0.000000000000000000000000000000003426 134.0
HKD2_k127_4613418_6 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000007214 142.0
HKD2_k127_4613418_7 YhhN family - - - 0.000000000000000000000001354 108.0
HKD2_k127_4613418_8 MerR, DNA binding - - - 0.0000000000000000003369 86.0
HKD2_k127_4613418_9 - - - - 0.00000000000000003975 89.0
HKD2_k127_4628533_0 Major Facilitator Superfamily K08222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 514.0
HKD2_k127_4628533_1 Putative amidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 511.0
HKD2_k127_4628533_2 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971 426.0
HKD2_k127_4628533_3 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 360.0
HKD2_k127_4628533_4 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 353.0
HKD2_k127_4628533_5 GNAT acetyltransferase K06976 - - 0.000000000000000000000000000000003716 138.0
HKD2_k127_4628533_6 Histidine kinase - - - 0.0000000000000000000001248 97.0
HKD2_k127_470181_0 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 315.0
HKD2_k127_470181_1 DNA-binding transcription factor activity K02470,K03892 - 5.99.1.3 0.000000000000000000000000000000000000004656 148.0
HKD2_k127_470181_2 Cupin domain - - - 0.0000000000000000000000000000000009555 133.0
HKD2_k127_471947_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 7.865e-308 953.0
HKD2_k127_471947_1 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 459.0
HKD2_k127_4791808_0 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 410.0
HKD2_k127_4791808_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 291.0
HKD2_k127_4791808_2 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000003902 145.0
HKD2_k127_479276_0 ABC transporter K06158 - - 6.547e-194 623.0
HKD2_k127_479276_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 479.0
HKD2_k127_479276_2 Psort location CytoplasmicMembrane, score 10.00 K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 435.0
HKD2_k127_479276_3 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 333.0
HKD2_k127_479276_4 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 297.0
HKD2_k127_479276_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000003698 77.0
HKD2_k127_479276_6 - - - - 0.00000000622 66.0
HKD2_k127_479276_7 Putative zinc-finger - - - 0.000001456 57.0
HKD2_k127_4836409_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 299.0
HKD2_k127_4836409_1 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000005321 188.0
HKD2_k127_4836409_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000102 181.0
HKD2_k127_4836409_3 Domain of unknown function (DUF4177) - - - 0.00000000002781 64.0
HKD2_k127_4899576_0 lipoprotein YddW precursor K01189 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 329.0
HKD2_k127_4899576_1 PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 306.0
HKD2_k127_5027955_0 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 464.0
HKD2_k127_5027955_1 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 316.0
HKD2_k127_5027955_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007688 255.0
HKD2_k127_5027955_3 COG0346 LactoylglutaTHIone lyase and related lyases - - - 0.00000000000000000000000000000000000000003192 154.0
HKD2_k127_5044251_0 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 393.0
HKD2_k127_5044251_1 TIGRFAM arsenite-activated ATPase ArsA K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 385.0
HKD2_k127_5044251_2 Virulence-associated protein E - - - 0.000000000000000000000000000000000000000000000000000000445 196.0
HKD2_k127_507982_0 Rhodanese Homology Domain K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 349.0
HKD2_k127_507982_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000004812 221.0
HKD2_k127_507982_2 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000000000000000000000000000000000000000000808 205.0
HKD2_k127_5113152_0 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 490.0
HKD2_k127_5113152_1 - - - - 0.000000000000000000000000000000000000000000000000000000003582 202.0
HKD2_k127_5113152_2 - - - - 0.0000000000000000000000000000000000000000000000000001678 187.0
HKD2_k127_5113152_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000001469 107.0
HKD2_k127_5114599_0 ABC transporter K06147 - - 1.064e-237 747.0
HKD2_k127_5114599_1 TaqI-like C-terminal specificity domain K07317 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 436.0
HKD2_k127_5114599_10 Protein of unknown function (DUF1232) - - - 0.00000002226 58.0
HKD2_k127_5114599_2 Cell Wall K01449 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000004736 248.0
HKD2_k127_5114599_3 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000009994 215.0
HKD2_k127_5114599_4 Chromate transport protein K07240 - - 0.0000000000000000000000000000000000000000000000000000139 194.0
HKD2_k127_5114599_5 Chromate transport protein K07240 - - 0.0000000000000000000000000000000000000000000000000008463 188.0
HKD2_k127_5114599_6 Involved in the degradation of specific anti-sigma factors - - - 0.000000000000000000000000000000000000000000000000001932 190.0
HKD2_k127_5114599_7 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000003864 162.0
HKD2_k127_5114599_8 - - - - 0.0000000000000000000000000001623 121.0
HKD2_k127_5114599_9 - - - - 0.000000000000000000000000002647 117.0
HKD2_k127_5133537_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008876 281.0
HKD2_k127_5133537_1 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000949 203.0
HKD2_k127_5133537_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000006442 185.0
HKD2_k127_5133537_3 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000004052 144.0
HKD2_k127_5133537_4 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000002328 107.0
HKD2_k127_5133537_5 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - 0.000000003182 58.0
HKD2_k127_5142441_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 7.2e-322 995.0
HKD2_k127_5142441_1 PFAM Peptidase M20 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 496.0
HKD2_k127_5142441_2 potassium uptake protein, TrkH family K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 483.0
HKD2_k127_5142441_3 Potassium uptake protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 288.0
HKD2_k127_5142441_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000003279 229.0
HKD2_k127_5142441_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000004213 201.0
HKD2_k127_5142441_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000004692 174.0
HKD2_k127_5142441_7 Ribosomal protein L35 K02916 - - 0.00000000000000001052 84.0
HKD2_k127_5156959_0 Carbohydrate kinase, FGGY K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 463.0
HKD2_k127_5156959_1 - - - - 0.0000000000000000000000000000000001084 139.0
HKD2_k127_5156959_2 HD domain - - - 0.000000000000000000000000001258 125.0
HKD2_k127_5158482_0 stage II sporulation protein E K06382 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 537.0
HKD2_k127_5158482_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 411.0
HKD2_k127_5158482_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000001087 256.0
HKD2_k127_5158482_3 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000006619 206.0
HKD2_k127_5158482_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000005099 196.0
HKD2_k127_5158482_5 PFAM RNA binding S1 domain protein K07570,K07571 - - 0.0000000000000000000000000000000000000000000003951 170.0
HKD2_k127_5158482_6 SMART serine K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000003291 171.0
HKD2_k127_5173515_0 spore germination protein K06295 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 511.0
HKD2_k127_5173515_1 Spore germination B3/ GerAC like, C-terminal K06297 - - 0.00000000000000000000000000000000000000000000000000000000000000005526 237.0
HKD2_k127_5173515_2 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000001192 133.0
HKD2_k127_5173515_3 Protein of unknown function (DUF1653) - - - 0.0000000000000000000000000002189 115.0
HKD2_k127_5173515_4 Spore gernimation protein K06296 - - 0.00000002925 65.0
HKD2_k127_5173515_5 cheY-homologous receiver domain - - - 0.0000001149 57.0
HKD2_k127_5183750_0 Carboxypeptidase K01308 - 3.4.19.11 3.05e-208 654.0
HKD2_k127_5183750_1 transcriptional regulator K21900 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005315 285.0
HKD2_k127_5183750_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005458 264.0
HKD2_k127_5183750_3 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000002651 231.0
HKD2_k127_5183750_4 - - - - 0.000000000000000000000000000000000000004392 154.0
HKD2_k127_5183750_5 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000001606 104.0
HKD2_k127_5190280_0 pyruvate phosphate dikinase, PEP K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1250.0
HKD2_k127_5190280_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 557.0
HKD2_k127_5190280_2 Bacterial transcription activator, effector binding domain K13653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 492.0
HKD2_k127_5190280_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 367.0
HKD2_k127_5190280_4 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004734 282.0
HKD2_k127_5190280_5 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000697 213.0
HKD2_k127_5194838_0 Diguanylate cyclase - - - 7.899e-224 701.0
HKD2_k127_5194838_1 transcriptional regulator, MerR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 404.0
HKD2_k127_5194838_2 Bacterial Ig-like domain 2 - - - 0.00000000000001396 79.0
HKD2_k127_5200919_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.434e-203 638.0
HKD2_k127_5200919_1 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000001895 139.0
HKD2_k127_5204804_0 hydrogenase large subunit K00336,K18332 - 1.12.1.3,1.6.5.3 7.529e-260 811.0
HKD2_k127_5204804_1 Permease K06901 - - 1.343e-213 671.0
HKD2_k127_5204804_2 Oxidoreductase 2-nitropropane dioxygenase family protein - - - 0.0000000003988 61.0
HKD2_k127_5207742_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03169 - 5.99.1.2 0.0 1111.0
HKD2_k127_5207742_1 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1035.0
HKD2_k127_5207742_10 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 360.0
HKD2_k127_5207742_11 breast cancer carboxy-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 295.0
HKD2_k127_5207742_12 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000005087 222.0
HKD2_k127_5207742_13 transglycosylase K08309 - - 0.000000000000000000000000000000000000000000000000003071 187.0
HKD2_k127_5207742_14 Domain of unknown function (DUF4349) - - - 0.00000000000000000000000000000000000000000000001044 186.0
HKD2_k127_5207742_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.868e-282 892.0
HKD2_k127_5207742_3 Histidine kinase - - - 2.343e-212 670.0
HKD2_k127_5207742_4 response regulator K07720 - - 2.495e-197 628.0
HKD2_k127_5207742_5 ABC-type xylose transport system, periplasmic component K10546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 601.0
HKD2_k127_5207742_6 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 492.0
HKD2_k127_5207742_7 PFAM Periplasmic binding protein LacI transcriptional regulator K10543,K10820 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 462.0
HKD2_k127_5207742_8 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 454.0
HKD2_k127_5207742_9 Periplasmic binding protein LacI transcriptional regulator K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 430.0
HKD2_k127_5208748_0 M3B, thimet oligopeptidase F K08602 - - 3.674e-237 747.0
HKD2_k127_5208748_1 PFAM Aminotransferase class I and II K00639,K00652,K01906 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47,6.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 611.0
HKD2_k127_5208748_10 amine dehydrogenase activity - - - 0.00000000000000000000001409 117.0
HKD2_k127_5208748_11 CotJB protein K06333 - - 0.0000000000000000000002867 99.0
HKD2_k127_5208748_12 Spore coat associated protein JA (CotJA) - - - 0.000000005262 59.0
HKD2_k127_5208748_2 amidohydrolase K21613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 496.0
HKD2_k127_5208748_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 317.0
HKD2_k127_5208748_4 Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation K01305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 314.0
HKD2_k127_5208748_5 PFAM Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 298.0
HKD2_k127_5208748_6 PFAM Manganese containing catalase K06334 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 284.0
HKD2_k127_5208748_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007169 292.0
HKD2_k127_5208748_8 response regulator receiver K07775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003297 260.0
HKD2_k127_5208748_9 Putative amidase domain - - - 0.0000000000000000000000000000000000000000003971 168.0
HKD2_k127_5212004_0 Psort location Cytoplasmic, score K15986 - 3.6.1.1 9.746e-204 647.0
HKD2_k127_5212004_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 475.0
HKD2_k127_5212004_2 PFAM Sulfite exporter TauE SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003555 283.0
HKD2_k127_5212004_3 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 0.000000000000000000000000000000000000000000002856 166.0
HKD2_k127_5212004_4 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000008634 140.0
HKD2_k127_5219538_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0 1172.0
HKD2_k127_5219538_1 Formyltetrahydrofolate synthetase K01938 - 6.3.4.3 2.72e-264 823.0
HKD2_k127_5219538_2 Glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 447.0
HKD2_k127_5219538_3 Ami_3 - - - 0.0000000000000000000000003558 108.0
HKD2_k127_5240531_0 spore germination protein K06295 - - 9.279e-260 809.0
HKD2_k127_5240531_1 PFAM spore germination B3 GerAC K06297 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 473.0
HKD2_k127_5240531_2 PFAM mannose-6-phosphate isomerase type I K01809 - 5.3.1.8 0.00000000000000000000000000000000000000000000000005264 188.0
HKD2_k127_5240531_3 Spore germination protein - - - 0.000000000000000000000000000000000008527 138.0
HKD2_k127_5240531_4 - - - - 0.0000000000000000000003123 97.0
HKD2_k127_5240531_5 Superfamily I DNA and RNA K03657 - 3.6.4.12 0.00007344 45.0
HKD2_k127_5242457_0 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 439.0
HKD2_k127_5242457_1 cyanophycin synthetase K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000292 217.0
HKD2_k127_5243235_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 6.859e-213 666.0
HKD2_k127_5243235_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 376.0
HKD2_k127_5243235_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 361.0
HKD2_k127_5253140_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 619.0
HKD2_k127_5253140_1 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 395.0
HKD2_k127_5253140_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000007142 226.0
HKD2_k127_5253140_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000009765 186.0
HKD2_k127_5253140_4 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis K06208 - 5.4.99.5 0.000000000000000000000000000000007296 130.0
HKD2_k127_5253140_5 - - - - 0.00000001183 63.0
HKD2_k127_5255237_0 hydrolase, family 65, central catalytic K00691 - 2.4.1.8 0.0 1232.0
HKD2_k127_5255237_1 hydrolase, family 65, central catalytic K18783,K21355 GO:0003674,GO:0003824,GO:0004645,GO:0016740,GO:0016757,GO:0016758 2.4.1.279,2.4.1.332 0.0 1148.0
HKD2_k127_5255237_2 ABC transporter, permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 457.0
HKD2_k127_5255237_3 Haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 323.0
HKD2_k127_5255237_4 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000004059 229.0
HKD2_k127_5267391_0 Biotin and Thiamin Synthesis associated K03150 - 4.1.99.19 1.251e-203 643.0
HKD2_k127_5267391_1 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 - - 4.605e-200 631.0
HKD2_k127_5267391_10 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007327 280.0
HKD2_k127_5267391_11 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000003777 231.0
HKD2_k127_5267391_12 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000000000000000000000000000000000000000000002114 226.0
HKD2_k127_5267391_13 Molybdenum cofactor synthesis domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001422 219.0
HKD2_k127_5267391_14 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000002182 210.0
HKD2_k127_5267391_15 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0000000000000000000000000002657 119.0
HKD2_k127_5267391_16 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000008172 113.0
HKD2_k127_5267391_17 hydrogenase large subunit K00336,K18332 - 1.12.1.3,1.6.5.3 0.0000000000008375 69.0
HKD2_k127_5267391_2 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 498.0
HKD2_k127_5267391_3 maturation GTPase HydF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 467.0
HKD2_k127_5267391_4 M42 glutamyl aminopeptidase K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 438.0
HKD2_k127_5267391_5 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 449.0
HKD2_k127_5267391_6 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 396.0
HKD2_k127_5267391_7 SMART Elongator protein 3 MiaB NifB K01012,K16180 - 2.8.1.6,5.4.99.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 397.0
HKD2_k127_5267391_8 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 306.0
HKD2_k127_5267391_9 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 287.0
HKD2_k127_5276943_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000003993 184.0
HKD2_k127_5276943_1 Branched-chain amino acid transport system / permease component K10440 - - 0.00000000000000000000000000735 115.0
HKD2_k127_5276943_2 Branched-chain amino acid transport system / permease component K10440 - - 0.000005792 49.0
HKD2_k127_5288312_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.099e-284 885.0
HKD2_k127_5288312_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000007698 182.0
HKD2_k127_5288312_2 Domain of unknown function (DUF2382) - - - 0.00000000000000000000000000000000000000004675 156.0
HKD2_k127_5288312_3 Domain of unknown function (DUF2382) - - - 0.00000000000000000000000000000006634 134.0
HKD2_k127_5290368_0 Amidohydrolase family K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 571.0
HKD2_k127_5290368_1 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 443.0
HKD2_k127_5290368_3 - - - - 0.0000000000000000000000001817 108.0
HKD2_k127_5290368_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000001357 94.0
HKD2_k127_5300322_0 Belongs to the peptidase S8 family K01361 - 3.4.21.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 528.0
HKD2_k127_5300322_1 Cell Wall Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006146 242.0
HKD2_k127_5300322_2 aminoacyl-histidine dipeptidase K01270 - - 0.0000000000000000000000000000000000000000000000000000000000000007911 223.0
HKD2_k127_5300322_3 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000000000003581 188.0
HKD2_k127_5300322_4 QueT transporter - - - 0.0000000000000000000000000000000000000000006843 162.0
HKD2_k127_5322621_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 387.0
HKD2_k127_5322621_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K18816 - 2.3.1.82 0.000000000000000000000000000000000000000000000000001761 184.0
HKD2_k127_5322621_2 - - - - 0.000000000000000000000000000000000000000000000001297 180.0
HKD2_k127_5322621_3 - - - - 0.00000000000000000000008249 111.0
HKD2_k127_53396_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 397.0
HKD2_k127_53396_1 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 389.0
HKD2_k127_53396_10 - - - - 0.0002999 44.0
HKD2_k127_53396_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001609 240.0
HKD2_k127_53396_3 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000002764 246.0
HKD2_k127_53396_4 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000001888 187.0
HKD2_k127_53396_5 Protein of unknown function (DUF3243) - - - 0.000000000000000000000005364 104.0
HKD2_k127_53396_6 Domain of unknown function (DUF4440) - - - 0.000000000000000004235 89.0
HKD2_k127_53396_8 HD domain - - - 0.0000001609 59.0
HKD2_k127_53396_9 - - - - 0.00001955 52.0
HKD2_k127_5342860_0 metalloendopeptidase activity - - - 9.013e-218 685.0
HKD2_k127_5342860_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 494.0
HKD2_k127_5342860_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 285.0
HKD2_k127_5342860_3 Acetyltransferase, gnat family - - - 0.0000000000000000000000000000000000000000000000000001828 190.0
HKD2_k127_5342860_4 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000005955 82.0
HKD2_k127_5344513_0 Domain of unknown function (DUF362) - - - 1.906e-223 695.0
HKD2_k127_5344513_1 Threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000002188 218.0
HKD2_k127_5355230_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.888e-289 896.0
HKD2_k127_5355230_1 metal-dependent phosphohydrolase, HD sub domain - - - 6.949e-204 664.0
HKD2_k127_5355230_10 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000003323 100.0
HKD2_k127_5355230_11 Lipopolysaccharide assembly protein A domain - - - 0.0000000003962 66.0
HKD2_k127_5355230_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 484.0
HKD2_k127_5355230_3 Domain of unknown function (DUF4474) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 370.0
HKD2_k127_5355230_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 327.0
HKD2_k127_5355230_5 PfkB family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 321.0
HKD2_k127_5355230_6 Glyoxalase K04750 - - 0.00000000000000000000000000000000000000000000000000000000000000000000028 239.0
HKD2_k127_5355230_7 Pfam:DUF1498 - - - 0.00000000000000000000000000000000000000000000000000000000000000001983 230.0
HKD2_k127_5355230_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000008155 149.0
HKD2_k127_5355230_9 Polysaccharide biosynthesis C-terminal domain - - - 0.00000000000000000000003333 99.0
HKD2_k127_5356207_0 TIGRFAM arsenite-activated ATPase ArsA K01551 - 3.6.3.16 9.387e-223 695.0
HKD2_k127_5356207_1 chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 572.0
HKD2_k127_5356207_10 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000001931 145.0
HKD2_k127_5356207_11 - - - - 0.00000000000000000000000000000000003131 143.0
HKD2_k127_5356207_12 PFAM Thioredoxin domain - - - 0.0000000000000000000000000005107 116.0
HKD2_k127_5356207_13 Protein of unknown function (DUF3006) - - - 0.00000000000000001105 84.0
HKD2_k127_5356207_14 Phage integrase, N-terminal SAM-like domain K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.00000000000001607 84.0
HKD2_k127_5356207_15 - - - - 0.0000000000005343 73.0
HKD2_k127_5356207_16 - - - - 0.00002823 53.0
HKD2_k127_5356207_2 TIGRFAM Arsenical-resistance protein K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 544.0
HKD2_k127_5356207_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 314.0
HKD2_k127_5356207_4 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003593 235.0
HKD2_k127_5356207_5 PFAM VanW family protein K18346 - - 0.000000000000000000000000000000000000000000000000000000000000006753 233.0
HKD2_k127_5356207_6 Arsenical resistance operon trans-acting repressor ArsD - - - 0.0000000000000000000000000000000000000000000000000000000001593 204.0
HKD2_k127_5356207_7 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000000000000004586 203.0
HKD2_k127_5356207_8 regulatory protein, arsR K03892 - - 0.0000000000000000000000000000000000000001656 153.0
HKD2_k127_5356207_9 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000000000000000000004456 152.0
HKD2_k127_5358750_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 5.481e-211 675.0
HKD2_k127_5358750_1 DAK2 domain fusion protein YloV K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 572.0
HKD2_k127_5358750_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000002455 223.0
HKD2_k127_5358750_3 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000003016 187.0
HKD2_k127_5358750_4 Asp23 family, cell envelope-related function - - - 0.0000000000000000000000000000000000000000004877 160.0
HKD2_k127_5358750_5 Psort location Cytoplasmic, score - - - 0.000000000000000000001853 98.0
HKD2_k127_5358750_6 Small acid-soluble spore - - - 0.00000000000000007926 82.0
HKD2_k127_5360213_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 573.0
HKD2_k127_5360213_1 Arginine dihydrolase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 520.0
HKD2_k127_5360213_2 Biofilm formation stimulator VEG - - - 0.000000000000000000000000000114 117.0
HKD2_k127_5361017_0 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001647 257.0
HKD2_k127_5361017_1 IA, variant 1 K01091,K06019 - 3.1.3.18,3.6.1.1 0.00000000000000000000000000000000000000000000000000000000001159 220.0
HKD2_k127_5361017_2 NLP P60 protein - - - 0.0000000000000000000000000000000000000000000006281 177.0
HKD2_k127_5361017_3 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000003322 147.0
HKD2_k127_5361017_4 - - - - 0.000000000000001024 82.0
HKD2_k127_5361017_5 - K21471 - - 0.00000000000001755 85.0
HKD2_k127_5361017_6 SAM-dependent methyltransferase - - - 0.0000000001673 63.0
HKD2_k127_5361017_7 - - - - 0.000000004029 64.0
HKD2_k127_5367380_0 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K03763 - 2.7.7.7 0.0 1553.0
HKD2_k127_5367380_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008407 461.0
HKD2_k127_5367380_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 326.0
HKD2_k127_5367380_3 Psort location CytoplasmicMembrane, score K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 298.0
HKD2_k127_5367380_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002875 256.0
HKD2_k127_5367380_5 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000000003603 177.0
HKD2_k127_5368070_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 578.0
HKD2_k127_5368070_1 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation K07067 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 447.0
HKD2_k127_5368070_2 Mazg nucleotide pyrophosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000005207 189.0
HKD2_k127_5369232_0 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 370.0
HKD2_k127_5369232_1 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 348.0
HKD2_k127_5369232_2 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 324.0
HKD2_k127_5369232_3 DNA polymerase alpha chain like domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001938 269.0
HKD2_k127_5375211_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 477.0
HKD2_k127_5375211_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 472.0
HKD2_k127_5375211_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 370.0
HKD2_k127_5375211_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 366.0
HKD2_k127_5375211_4 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000000000000000003656 195.0
HKD2_k127_5375211_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000004163 179.0
HKD2_k127_5375211_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000004922 62.0
HKD2_k127_5375669_0 IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 349.0
HKD2_k127_5375669_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 304.0
HKD2_k127_5375669_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008315 301.0
HKD2_k127_5375669_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 291.0
HKD2_k127_5375669_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006678 278.0
HKD2_k127_5375669_5 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.00000000000000000000000000000000000000000000000000000000000008929 214.0
HKD2_k127_5375669_6 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000744 208.0
HKD2_k127_5375669_7 isochorismatase - - - 0.0000001449 55.0
HKD2_k127_5388936_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1183.0
HKD2_k127_5388936_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 467.0
HKD2_k127_5388936_2 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 352.0
HKD2_k127_5388936_3 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 353.0
HKD2_k127_5388936_4 glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 349.0
HKD2_k127_5388936_5 S-layer homology domain - - - 0.00000000000000000000000000000000004043 154.0
HKD2_k127_5393905_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1870.0
HKD2_k127_5393905_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 609.0
HKD2_k127_5393905_10 Protein of unknown function (DUF2508) - - - 0.000000000000009605 77.0
HKD2_k127_5393905_2 ferredoxin oxidoreductase K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 539.0
HKD2_k127_5393905_3 Pfam:Cache_1 K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 453.0
HKD2_k127_5393905_4 oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 338.0
HKD2_k127_5393905_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 345.0
HKD2_k127_5393905_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 316.0
HKD2_k127_5393905_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000001953 154.0
HKD2_k127_5393905_8 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate family K00171 - 1.2.7.1 0.0000000000000000000000000000000000000001886 152.0
HKD2_k127_5393905_9 SigmaK-factor processing regulatory protein BofA K06317 - - 0.000000000000000002937 87.0
HKD2_k127_5397357_0 PFAM EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 465.0
HKD2_k127_5397357_1 Domain of unknown function (DUF4111) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 306.0
HKD2_k127_5397357_2 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005696 251.0
HKD2_k127_5399765_0 PFAM Cys Met metabolism K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 593.0
HKD2_k127_5399765_1 Sigma factor regulator C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 459.0
HKD2_k127_5399765_10 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 - 4.4.1.21 0.0007318 42.0
HKD2_k127_5399765_2 transferase activity, transferring acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 441.0
HKD2_k127_5399765_3 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 363.0
HKD2_k127_5399765_4 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 353.0
HKD2_k127_5399765_5 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004142 239.0
HKD2_k127_5399765_6 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000009927 201.0
HKD2_k127_5399765_7 Small Multidrug Resistance protein K11741 - - 0.0000000000000000000000000000000000000000000001647 169.0
HKD2_k127_5399765_8 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000004625 172.0
HKD2_k127_5399765_9 Cupin 2, conserved barrel domain protein K21700 - - 0.00000000000000000000000000000000000000004134 152.0
HKD2_k127_5415414_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.898e-263 819.0
HKD2_k127_5415414_1 Sigma54 specific transcriptional regulator, Fis family K21405 - - 5.114e-254 797.0
HKD2_k127_5415414_2 Belongs to the bacterial solute-binding protein 3 family K02030,K02424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 373.0
HKD2_k127_5415414_3 COG0765 ABC-type amino acid transport system, permease component K10009 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009175 276.0
HKD2_k127_5428381_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 576.0
HKD2_k127_5428381_1 thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 305.0
HKD2_k127_5428381_2 Glycosyl hydrolase family 26 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 316.0
HKD2_k127_5428381_3 50S ribosomal protein L31 K02909 - - 0.000000000000000000000000000001675 121.0
HKD2_k127_5428424_0 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 585.0
HKD2_k127_5428424_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000003488 148.0
HKD2_k127_5428424_2 - - - - 0.000000000000000000000000000004307 124.0
HKD2_k127_5428424_3 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.00000000000000008779 79.0
HKD2_k127_5428424_4 - - - - 0.00000002577 61.0
HKD2_k127_5428644_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.1e-234 739.0
HKD2_k127_5428644_1 FeoA K04758 - - 0.0000000000000000001113 90.0
HKD2_k127_5428644_2 Belongs to the UPF0473 family - - - 0.000000000001478 69.0
HKD2_k127_543103_0 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 550.0
HKD2_k127_543103_1 helix_turn_helix, cAMP Regulatory protein K21562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 285.0
HKD2_k127_543103_2 Cell Wall Hydrolase K01449 - 3.5.1.28 0.000002504 56.0
HKD2_k127_5440964_0 helicase K07464,K10844 - 3.1.12.1,3.6.4.12 6.124e-244 776.0
HKD2_k127_5440964_1 PFAM Aminotransferase class I and II K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 3.717e-195 614.0
HKD2_k127_5440964_10 PFAM Transglutaminase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000005561 245.0
HKD2_k127_5440964_11 Uncharacterized protein conserved in bacteria (DUF2225) K09766 - - 0.0000000000000000000000000000000000000000000000000000000003021 209.0
HKD2_k127_5440964_12 PFAM Sporulation and spore germination - - - 0.00000000000000000000000000000000000000000000191 172.0
HKD2_k127_5440964_13 acetyltransferase - - - 0.00000000000000000000000000000000000000000002831 172.0
HKD2_k127_5440964_14 PFAM Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000003614 173.0
HKD2_k127_5440964_15 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000001346 159.0
HKD2_k127_5440964_16 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000001014 139.0
HKD2_k127_5440964_17 TIGRFAM spore photoproduct lyase K03716 GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0016829,GO:0016830,GO:0043167,GO:0043169,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0070283,GO:0140097 4.1.99.14 0.00000000000000000000000000000002473 127.0
HKD2_k127_5440964_18 - - - - 0.00000005617 56.0
HKD2_k127_5440964_19 5-bromo-4-chloroindolyl phosphate hydrolysis protein - - - 0.000001205 60.0
HKD2_k127_5440964_2 cell division protein FtsA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 586.0
HKD2_k127_5440964_21 Small acid-soluble spore protein H family - - - 0.00005936 47.0
HKD2_k127_5440964_3 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 525.0
HKD2_k127_5440964_4 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 521.0
HKD2_k127_5440964_5 THUMP K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 500.0
HKD2_k127_5440964_6 Histidine kinase K11527 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007413 449.0
HKD2_k127_5440964_7 PFAM ATPase associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 385.0
HKD2_k127_5440964_8 PFAM VanW family protein K18346 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 321.0
HKD2_k127_5440964_9 hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000032 246.0
HKD2_k127_5443375_0 Histidine kinase - - - 1.09e-215 684.0
HKD2_k127_5443375_1 Endonuclease exonuclease phosphatase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 406.0
HKD2_k127_5443375_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 397.0
HKD2_k127_5443375_3 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 363.0
HKD2_k127_5443375_4 Desulfoferrodoxin ferrous iron-binding K05919 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016721,GO:0019430,GO:0022900,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.2 0.00000000000000000000000000000000000000000000000000000000007777 207.0
HKD2_k127_5443375_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000004869 175.0
HKD2_k127_5443375_6 FAD dependent oxidoreductase K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 0.0000000000000000000000000000000000000003964 153.0
HKD2_k127_5443375_7 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000001775 60.0
HKD2_k127_5445066_0 potassium uptake protein TrkH K03498 - - 9.564e-213 670.0
HKD2_k127_5445066_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 605.0
HKD2_k127_5445066_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 445.0
HKD2_k127_5445066_3 K transport systems, NAD-binding component K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000002376 236.0
HKD2_k127_5445066_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000001998 205.0
HKD2_k127_5445066_5 Capsule synthesis protein K07282 - - 0.000004527 53.0
HKD2_k127_5456777_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 559.0
HKD2_k127_5456777_1 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 333.0
HKD2_k127_5456777_2 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000228 270.0
HKD2_k127_5466790_0 aminopeptidase K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 565.0
HKD2_k127_5466790_1 aminopeptidase K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 541.0
HKD2_k127_5466790_2 Radical SAM K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 501.0
HKD2_k127_5466790_3 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 469.0
HKD2_k127_5466790_4 ATPase. Has a role at an early stage in the morphogenesis of the spore coat K06398 GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000004669 231.0
HKD2_k127_5466790_5 phospholipase C K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000003266 228.0
HKD2_k127_5466790_6 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000004326 173.0
HKD2_k127_5468421_0 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 510.0
HKD2_k127_5468421_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001161 258.0
HKD2_k127_5474028_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 546.0
HKD2_k127_5474028_1 Putative cell wall binding repeat 2 - - - 0.00000000000000000000000000000000000000000000000000000002164 199.0
HKD2_k127_5474028_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000000000000001574 195.0
HKD2_k127_5474028_3 Glycoprotease K14742 - - 0.000000000000000000000000000000000000000000000000000001646 205.0
HKD2_k127_5474028_4 Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins - - - 0.0000000000000000000000000000000000000000000000000007094 189.0
HKD2_k127_5474028_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000001904 175.0
HKD2_k127_5474028_6 Acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000008658 168.0
HKD2_k127_5487709_0 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 598.0
HKD2_k127_5487709_1 Diguanylate cyclase K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000002321 232.0
HKD2_k127_5511700_0 Dehydrogenase K00121,K00148 - 1.1.1.1,1.1.1.284,1.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 532.0
HKD2_k127_5511700_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 318.0
HKD2_k127_5511700_2 Psort location CytoplasmicMembrane, score K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002108 253.0
HKD2_k127_5518029_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 2.917e-284 881.0
HKD2_k127_5518029_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 3.649e-265 823.0
HKD2_k127_5518029_10 Biotin-requiring enzyme - - - 0.00000000000000000000000000000003331 131.0
HKD2_k127_5518029_11 decarboxylase, gamma subunit - - - 0.000000005624 61.0
HKD2_k127_5518029_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.246e-257 806.0
HKD2_k127_5518029_3 decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 521.0
HKD2_k127_5518029_4 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 376.0
HKD2_k127_5518029_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 375.0
HKD2_k127_5518029_6 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 359.0
HKD2_k127_5518029_7 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000002722 219.0
HKD2_k127_5518029_8 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000002755 216.0
HKD2_k127_5518029_9 THIoesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000000000000000002754 170.0
HKD2_k127_5519577_0 CoA-substrate-specific enzyme activase - - - 0.0 2169.0
HKD2_k127_5519577_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 9.975e-237 741.0
HKD2_k127_5519577_10 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 488.0
HKD2_k127_5519577_11 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 481.0
HKD2_k127_5519577_12 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 357.0
HKD2_k127_5519577_13 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 336.0
HKD2_k127_5519577_14 Putative sugar diacid recognition K02647 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 336.0
HKD2_k127_5519577_15 Putative PD-(D/E)XK phosphodiesterase (DUF2161) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 307.0
HKD2_k127_5519577_16 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 295.0
HKD2_k127_5519577_17 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 286.0
HKD2_k127_5519577_18 radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001538 269.0
HKD2_k127_5519577_19 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000001596 241.0
HKD2_k127_5519577_2 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 5.925e-231 720.0
HKD2_k127_5519577_20 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000004788 199.0
HKD2_k127_5519577_21 Putative inner membrane exporter, YdcZ K09936 - - 0.000000000000000000000000000000000000000000000003473 176.0
HKD2_k127_5519577_22 Putative inner membrane exporter, YdcZ K09936 - - 0.0000000000000000000000000000000000000001309 154.0
HKD2_k127_5519577_3 Sugar (pentulose and hexulose) kinases K00854 - 2.7.1.17 1.137e-230 723.0
HKD2_k127_5519577_4 Belongs to the xylose isomerase family K01805 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.5 3.244e-229 715.0
HKD2_k127_5519577_5 glycine radical enzyme, YjjI family - - - 7.39e-225 706.0
HKD2_k127_5519577_6 M18 family aminopeptidase K01267 - 3.4.11.21 1.035e-208 655.0
HKD2_k127_5519577_7 Gluconate K03299 - - 6.711e-195 617.0
HKD2_k127_5519577_8 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 525.0
HKD2_k127_5519577_9 aspartate-ammonia ligase K01914 - 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 504.0
HKD2_k127_5556254_0 ABC-type sugar transport system periplasmic component K17318 - - 1.888e-261 816.0
HKD2_k127_5556254_1 SMART Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 2.439e-243 753.0
HKD2_k127_5556254_2 PFAM Binding-protein-dependent transport system inner membrane component K17319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 497.0
HKD2_k127_5556254_3 PFAM Binding-protein-dependent transport system inner membrane component K17320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 485.0
HKD2_k127_5556254_4 response regulator K07720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 420.0
HKD2_k127_5559023_0 UPF0313 protein - - - 0.0 1079.0
HKD2_k127_5559023_1 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 340.0
HKD2_k127_5559023_2 - - - - 0.00000000000000000000000000000000000000000000000008879 179.0
HKD2_k127_5559023_3 Protein of unknown function (DUF3785) - - - 0.000000000000000000000000000000000000000000002274 168.0
HKD2_k127_5559023_4 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000225 156.0
HKD2_k127_5559023_5 - - - - 0.00000000000000139 81.0
HKD2_k127_5586909_0 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 536.0
HKD2_k127_5586909_1 BadF BadG BcrA BcrD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 354.0
HKD2_k127_5586909_2 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000000000000003263 229.0
HKD2_k127_5586909_3 Nodulation protein S (NodS) - - - 0.00000000000000000000000000002371 123.0
HKD2_k127_5586909_4 Small, acid-soluble spore proteins, alpha/beta type - - - 0.000000000000003255 77.0
HKD2_k127_5591050_0 SMART AAA ATPase K02315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 310.0
HKD2_k127_5591050_1 Replication initiation and membrane attachment - - - 0.00000000000000000000000000000000000000000000000000000000056 214.0
HKD2_k127_56293_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.903e-263 821.0
HKD2_k127_56293_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 411.0
HKD2_k127_5633536_0 MATE efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 553.0
HKD2_k127_5633536_1 Spore germination protein K06295 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 501.0
HKD2_k127_5633536_2 Spore germination protein K06296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 354.0
HKD2_k127_5633536_3 TIGRFAM germination protein, Ger(x)C family K06297 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 306.0
HKD2_k127_5633536_4 Domain of unknown function (4846) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001312 241.0
HKD2_k127_5633536_5 - - - - 0.00009549 48.0
HKD2_k127_5651780_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 596.0
HKD2_k127_5651780_1 Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 511.0
HKD2_k127_5651780_2 Formate nitrite K21993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 436.0
HKD2_k127_5651780_3 Protein of unknown function (DUF3231) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009747 270.0
HKD2_k127_5651780_4 - - - - 0.000000000000000000000007913 110.0
HKD2_k127_5664648_0 phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 578.0
HKD2_k127_5664648_1 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 342.0
HKD2_k127_5664648_2 family 18 K06306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006123 243.0
HKD2_k127_5671426_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 496.0
HKD2_k127_5671426_1 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 408.0
HKD2_k127_5671426_2 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16783,K16785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 357.0
HKD2_k127_5671426_3 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 350.0
HKD2_k127_5671426_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 304.0
HKD2_k127_5671426_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000001741 204.0
HKD2_k127_5671426_6 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000002693 189.0
HKD2_k127_5691502_0 Orn Lys Arg decarboxylase major K01585 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 449.0
HKD2_k127_5691502_1 Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 383.0
HKD2_k127_5691502_2 DNA polymerase III K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000005923 243.0
HKD2_k127_5691502_3 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000008799 232.0
HKD2_k127_5691502_4 TIGRFAM Sporulation integral membrane protein YtvI - - - 0.0000000000000000000000000000000000000000000000000000000000007047 223.0
HKD2_k127_5691502_5 Cyclic-di-AMP receptor - - - 0.000000000000000000000000000000000000000352 151.0
HKD2_k127_5691502_6 Protein of unknown function (DUF327) K09770 - - 0.000000000000000000000000000000002594 133.0
HKD2_k127_5691502_7 PSP1 domain protein - - - 0.0000000000000000000000000000003596 124.0
HKD2_k127_5691502_8 - - - - 0.00001591 47.0
HKD2_k127_5739275_0 Bacillus/Clostridium GerA spore germination protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 473.0
HKD2_k127_5739275_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206,K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001298 273.0
HKD2_k127_5739275_2 Spore germination B3/ GerAC like, C-terminal K06308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000198 250.0
HKD2_k127_5739275_3 Spore germination protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004712 248.0
HKD2_k127_5739491_0 PFAM Mannitol dehydrogenase, C-terminal domain K00040 - 1.1.1.57 1.707e-266 831.0
HKD2_k127_5739491_1 Catalyzes the dehydration of D-mannonate K01686 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008198,GO:0008927,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019585,GO:0019752,GO:0030145,GO:0032787,GO:0042839,GO:0042840,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0071704,GO:0072329,GO:1901575 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 597.0
HKD2_k127_5739491_2 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 587.0
HKD2_k127_5739491_3 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 419.0
HKD2_k127_5739491_4 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000007089 84.0
HKD2_k127_5750680_0 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 581.0
HKD2_k127_5750680_1 Histidine kinase K07718 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 482.0
HKD2_k127_5750680_2 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 443.0
HKD2_k127_5760056_0 Domain of unknown function (DUF1998) K06877 - - 0.0 1137.0
HKD2_k127_5760056_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 2.284e-276 860.0
HKD2_k127_5760056_10 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003069 283.0
HKD2_k127_5760056_11 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004092 279.0
HKD2_k127_5760056_12 PFAM Rubrerythrin - GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001017 263.0
HKD2_k127_5760056_13 Aminotransferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000006398 252.0
HKD2_k127_5760056_14 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000001216 244.0
HKD2_k127_5760056_15 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000244 229.0
HKD2_k127_5760056_16 GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000000001131 220.0
HKD2_k127_5760056_17 MgtC family K07507 - - 0.00000000000000000000000000000000000000000000000000000000003026 212.0
HKD2_k127_5760056_18 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00657,K07023 - 2.3.1.57 0.0000000000000000000000000000000000000000000000000000001344 199.0
HKD2_k127_5760056_19 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000001523 180.0
HKD2_k127_5760056_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 3.756e-268 831.0
HKD2_k127_5760056_20 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000008687 143.0
HKD2_k127_5760056_21 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000002235 150.0
HKD2_k127_5760056_22 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000002963 97.0
HKD2_k127_5760056_23 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000004665 89.0
HKD2_k127_5760056_24 asparagine synthase - - - 0.000000002229 61.0
HKD2_k127_5760056_25 Belongs to the serine threonine dehydratase family. DsdA subfamily K01753 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008721,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.3.1.18 0.000001943 49.0
HKD2_k127_5760056_26 Protein of unknown function (DUF402) K07586 - - 0.00005061 52.0
HKD2_k127_5760056_3 UvrD-like helicase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 620.0
HKD2_k127_5760056_4 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 601.0
HKD2_k127_5760056_5 aldolase class II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 548.0
HKD2_k127_5760056_6 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 343.0
HKD2_k127_5760056_7 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004902 285.0
HKD2_k127_5760056_8 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006413 278.0
HKD2_k127_5760056_9 Mpv17 / PMP22 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002432 276.0
HKD2_k127_5761653_0 Major facilitator superfamily - - - 2.343e-209 655.0
HKD2_k127_5761653_1 Abc transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 574.0
HKD2_k127_5761653_10 Peptidoglycan-binding domain 1 protein K01233,K21449 - 3.2.1.132 0.0000000002957 72.0
HKD2_k127_5761653_2 Psort location CytoplasmicMembrane, score K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 553.0
HKD2_k127_5761653_3 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 555.0
HKD2_k127_5761653_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 505.0
HKD2_k127_5761653_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 351.0
HKD2_k127_5761653_6 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 291.0
HKD2_k127_5761653_7 Glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002374 244.0
HKD2_k127_5761653_8 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000001257 176.0
HKD2_k127_5761653_9 - - - - 0.0000000001011 66.0
HKD2_k127_5766909_0 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 391.0
HKD2_k127_5766909_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002738 233.0
HKD2_k127_5766909_2 beta-lactamase domain protein K02238 - - 0.0000005975 53.0
HKD2_k127_5766909_3 Phosphotransferase enzyme family - - - 0.0001668 44.0
HKD2_k127_5778438_0 polygalacturonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 478.0
HKD2_k127_5778438_1 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000003705 197.0
HKD2_k127_5778438_2 PFAM Sporulation protein YtfJ - - - 0.000000000000000000000000000000000006976 139.0
HKD2_k127_5778438_3 Pectate lyase superfamily protein - - - 0.00000000000000000000000000000007396 132.0
HKD2_k127_5778438_4 - - - - 0.000009185 54.0
HKD2_k127_5790548_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 576.0
HKD2_k127_5790548_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 515.0
HKD2_k127_5790548_2 Hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 417.0
HKD2_k127_5790548_3 Rrf2 family - - - 0.0000000000000000000000000000000000000000000561 164.0
HKD2_k127_5790548_4 PFAM cytochrome - - - 0.00000000000000000000000000003312 121.0
HKD2_k127_5790548_5 hydrogenase maturation protease K03605 - - 0.00000000000000000000564 98.0
HKD2_k127_5830712_0 Heavy-metal-associated domain K17686 - 3.6.3.54 0.0 1116.0
HKD2_k127_5830712_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 3.016e-283 878.0
HKD2_k127_5830712_2 - - - - 0.0000000000000000000000000000000000000000000000000000001047 202.0
HKD2_k127_5830712_3 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000000000000002476 146.0
HKD2_k127_5830712_4 Heavy metal transport detoxification protein K07213 - - 0.0000000000000000000002765 97.0
HKD2_k127_5830712_5 TIGRFAM spore germination protein K06296 - - 0.00000005049 54.0
HKD2_k127_58340_0 PFAM Hydantoinase oxoprolinase - - - 0.0 1247.0
HKD2_k127_58340_1 Psort location CytoplasmicMembrane, score - - - 9.143e-244 758.0
HKD2_k127_58340_2 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 454.0
HKD2_k127_58340_3 PFAM regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 375.0
HKD2_k127_58340_4 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 346.0
HKD2_k127_58340_5 protein, YhcH YjgK YiaL family - - - 0.0000000000000000000000000000000000000000000000000000000000005708 213.0
HKD2_k127_58340_6 sequence-specific DNA binding - - - 0.00000000000000000000006442 104.0
HKD2_k127_5845843_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 6.08e-249 809.0
HKD2_k127_5845843_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 3.146e-205 649.0
HKD2_k127_5845843_10 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000004534 123.0
HKD2_k127_5845843_2 GAF domain K07777 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 496.0
HKD2_k127_5845843_3 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 455.0
HKD2_k127_5845843_4 Bacterial regulatory protein, Fis family K02481,K07714,K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 361.0
HKD2_k127_5845843_5 translation elongation factor K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000138 285.0
HKD2_k127_5845843_6 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000001324 269.0
HKD2_k127_5845843_7 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000001092 205.0
HKD2_k127_5845843_8 cobinamide kinase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000000000003033 201.0
HKD2_k127_5845843_9 Belongs to the phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000003542 188.0
HKD2_k127_585103_0 SMART Metal-dependent phosphohydrolase, HD region K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 540.0
HKD2_k127_585103_1 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 426.0
HKD2_k127_585103_2 sporulation protein K06438 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004485 267.0
HKD2_k127_585103_3 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.000000000000000000000000000000000000000000000000000000000000002312 224.0
HKD2_k127_585103_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.0000000000000000000000000000000000000000004813 163.0
HKD2_k127_585103_5 SigmaW regulon antibacterial - - - 0.00000000000000000000002468 100.0
HKD2_k127_585103_6 sporulation protein YqfC - - - 0.0000000000000000005763 89.0
HKD2_k127_5856150_0 Type II IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 512.0
HKD2_k127_5856150_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 376.0
HKD2_k127_5856150_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000006117 57.0
HKD2_k127_5856150_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000823 267.0
HKD2_k127_5856150_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004308 240.0
HKD2_k127_5856150_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000002447 172.0
HKD2_k127_5856150_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000005376 163.0
HKD2_k127_5856150_6 Type IV leader peptidase family K02278 - 3.4.23.43 0.00000000000000000000005821 104.0
HKD2_k127_5856150_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000688 94.0
HKD2_k127_5856150_8 Psort location Cytoplasmic, score - - - 0.0000000000001656 82.0
HKD2_k127_5856150_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000009899 68.0
HKD2_k127_58864_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 561.0
HKD2_k127_58864_1 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 510.0
HKD2_k127_58864_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 479.0
HKD2_k127_58864_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 347.0
HKD2_k127_58864_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 324.0
HKD2_k127_58864_5 Transcriptional regulator K05311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 308.0
HKD2_k127_58864_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000001251 128.0
HKD2_k127_5919174_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 533.0
HKD2_k127_5919174_1 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 323.0
HKD2_k127_5919174_2 B3/4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003294 278.0
HKD2_k127_601980_0 Tex-like protein N-terminal domain K06959 - - 3.218e-306 953.0
HKD2_k127_601980_1 S-layer domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000986 338.0
HKD2_k127_601980_2 SMART chemotaxis sensory transducer, histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000419 171.0
HKD2_k127_601980_3 Belongs to the UPF0735 family K06209 - 5.4.99.5 0.00000000000000000000000000000000002975 141.0
HKD2_k127_601980_4 Cell wall-binding protein - - - 0.000000000000000000000001377 121.0
HKD2_k127_6076229_0 Belongs to the arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 501.0
HKD2_k127_6076229_1 Alkylphosphonate utilization operon protein PhnA K06193 - - 0.000000000000000000000000000000000000000000000000000000000466 203.0
HKD2_k127_6076229_2 Domain of unknown function (DUF4180) - - - 0.00000000000000000000000000000000000000000000001585 173.0
HKD2_k127_6076229_3 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000001155 159.0
HKD2_k127_6076229_4 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000134 140.0
HKD2_k127_6076229_5 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000005873 134.0
HKD2_k127_6076229_6 TraX protein - - - 0.000000000000000000000000004612 122.0
HKD2_k127_6111066_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00244 - 1.3.5.4 7.569e-244 762.0
HKD2_k127_6111066_1 Catalyzes the sodium-dependent transport of glutamate K03312 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 405.0
HKD2_k127_6111066_2 PucR C-terminal helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 342.0
HKD2_k127_6111066_3 PFAM Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002452 249.0
HKD2_k127_6111066_4 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000005916 166.0
HKD2_k127_611340_0 Responsible for synthesis of pseudouridine from uracil K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000002477 256.0
HKD2_k127_611340_1 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002629 239.0
HKD2_k127_611340_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000293 211.0
HKD2_k127_611340_3 CBS domain - - - 0.000000000000000000000000000000000000006574 149.0
HKD2_k127_611340_4 Protein of unknown function (DUF2953) - - - 0.00000000000000000000000005878 116.0
HKD2_k127_611340_5 Domain of unknown function (DUF4363) - - - 0.00000000000000000003351 94.0
HKD2_k127_611340_6 Putative zinc-finger - - - 0.0000000000006889 74.0
HKD2_k127_6300094_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 1.061e-245 767.0
HKD2_k127_6300094_1 FAD dependent oxidoreductase K00302 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 487.0
HKD2_k127_6300094_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 381.0
HKD2_k127_6300094_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000007222 173.0
HKD2_k127_6300094_4 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000004889 168.0
HKD2_k127_6319793_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002008 287.0
HKD2_k127_6319793_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000002547 168.0
HKD2_k127_6319793_2 - - - - 0.000000000000000000000000000000000009297 144.0
HKD2_k127_6319793_3 Lysozyme inhibitor LprI - - - 0.000000000000000000000000000000007607 135.0
HKD2_k127_6319793_4 Methyltransferase domain - - - 0.000000000000000000000000000002363 123.0
HKD2_k127_6346191_0 ABC transporter transmembrane region K06147 - - 2.26e-265 829.0
HKD2_k127_6346191_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 1.341e-245 765.0
HKD2_k127_6346191_10 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002996 280.0
HKD2_k127_6346191_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004182 270.0
HKD2_k127_6346191_12 Cytochrome c biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006303 273.0
HKD2_k127_6346191_13 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000009765 181.0
HKD2_k127_6346191_14 Thioredoxin-like - - - 0.000000000000000000000000000000000000003985 153.0
HKD2_k127_6346191_15 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000002552 139.0
HKD2_k127_6346191_16 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000002341 136.0
HKD2_k127_6346191_17 - - - - 0.00000000000000000000000000000004419 127.0
HKD2_k127_6346191_18 - - - - 0.000000000000000000000000003456 118.0
HKD2_k127_6346191_19 Transcriptional regulator, CopG family K07723 - - 0.0000000000000000000000001814 108.0
HKD2_k127_6346191_2 ABC transporter K06147 - - 1.344e-240 755.0
HKD2_k127_6346191_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 590.0
HKD2_k127_6346191_4 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 578.0
HKD2_k127_6346191_5 Arsenical pump membrane protein K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 553.0
HKD2_k127_6346191_6 PFAM tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 475.0
HKD2_k127_6346191_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 475.0
HKD2_k127_6346191_8 Belongs to the TtcA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 462.0
HKD2_k127_6346191_9 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 309.0
HKD2_k127_6386584_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.117e-272 844.0
HKD2_k127_6386584_1 Cell surface receptor IPT TIG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 432.0
HKD2_k127_6386584_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 381.0
HKD2_k127_6386584_3 S-layer homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000312 286.0
HKD2_k127_6386584_4 S-layer homology domain - - - 0.00000000000000000000001005 119.0
HKD2_k127_6386584_5 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000797 71.0
HKD2_k127_6393906_0 Aminotransferase K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 573.0
HKD2_k127_6393906_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009894 537.0
HKD2_k127_6393906_10 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000000000000000000003653 167.0
HKD2_k127_6393906_11 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000002257 148.0
HKD2_k127_6393906_12 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000001998 152.0
HKD2_k127_6393906_2 Transmembrane secretion effector K08217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 420.0
HKD2_k127_6393906_3 DUF based on E. rectale Gene description (DUF3880) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 399.0
HKD2_k127_6393906_4 Psort location CytoplasmicMembrane, score K02028,K10041 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 389.0
HKD2_k127_6393906_5 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 346.0
HKD2_k127_6393906_6 Belongs to the bacterial solute-binding protein 3 family K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 322.0
HKD2_k127_6393906_7 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 287.0
HKD2_k127_6393906_8 WbqC-like protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003886 256.0
HKD2_k127_6393906_9 COG2211 Na melibiose symporter and related transporters K03292 - - 0.000000000000000000000000000000000000000000000000006446 198.0
HKD2_k127_6398579_0 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 5.353e-217 688.0
HKD2_k127_6398579_1 Cache domain K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 620.0
HKD2_k127_6398579_10 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000009925 173.0
HKD2_k127_6398579_11 Protein of unknown function (DUF1189) - - - 0.000000000000000000000000000000001513 140.0
HKD2_k127_6398579_12 Cell Wall Hydrolase K01449 - 3.5.1.28 0.00000000000002375 86.0
HKD2_k127_6398579_2 AMMECR1 K06990,K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 491.0
HKD2_k127_6398579_3 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 427.0
HKD2_k127_6398579_4 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 402.0
HKD2_k127_6398579_5 Rubrerythrin - GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005506,GO:0006091,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009266,GO:0009268,GO:0009408,GO:0009409,GO:0009628,GO:0009636,GO:0009651,GO:0009987,GO:0010035,GO:0010446,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0016999,GO:0017001,GO:0017144,GO:0022900,GO:0033554,GO:0034599,GO:0034605,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070417,GO:0070482,GO:0070887,GO:0071214,GO:0071236,GO:0071453,GO:0071467,GO:0071469,GO:0071470,GO:0071472,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:0104004,GO:1901700,GO:1901701,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009743 318.0
HKD2_k127_6398579_6 inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006761 278.0
HKD2_k127_6398579_7 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001128 257.0
HKD2_k127_6398579_8 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000001261 222.0
HKD2_k127_6398579_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000001345 194.0
HKD2_k127_6419068_0 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 574.0
HKD2_k127_6419068_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 515.0
HKD2_k127_6419068_2 Psort location Cytoplasmic, score 9.97 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 502.0
HKD2_k127_6419068_3 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 409.0
HKD2_k127_6419068_4 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002358 286.0
HKD2_k127_6419068_5 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002661 271.0
HKD2_k127_6419068_6 Magnesium transport protein CorA K03284 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000002269 243.0
HKD2_k127_6419068_7 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000003938 248.0
HKD2_k127_6419068_8 protein some members contain a von Willebrand factor type A - - - 0.000000000000000000000000000000000000000001147 158.0
HKD2_k127_6441867_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 4.8e-211 671.0
HKD2_k127_6441867_1 Beta-eliminating lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 583.0
HKD2_k127_6441867_10 - - - - 0.0000000000109 76.0
HKD2_k127_6441867_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 415.0
HKD2_k127_6441867_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 366.0
HKD2_k127_6441867_4 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002756 241.0
HKD2_k127_6441867_5 PFAM Capsule synthesis protein, CapA K07282 - - 0.0000000000000000000000000000000000000000000000000000000000001755 226.0
HKD2_k127_6441867_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000003786 206.0
HKD2_k127_6441867_7 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000000006018 156.0
HKD2_k127_6441867_8 metallocarboxypeptidase activity - - - 0.000000000000000000000000000000002829 135.0
HKD2_k127_6441867_9 FMN_bind - - - 0.0000000000000000000000000000002752 133.0
HKD2_k127_6442997_0 Mate efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 400.0
HKD2_k127_6442997_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 318.0
HKD2_k127_6442997_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 295.0
HKD2_k127_6442997_3 YbbR-like protein - - - 0.0000003439 52.0
HKD2_k127_6444486_0 ABC transporter - - - 3.178e-293 905.0
HKD2_k127_6444486_1 potassium uptake protein TrkH K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 603.0
HKD2_k127_6444486_2 domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009779 559.0
HKD2_k127_6444486_3 MATE efflux family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 433.0
HKD2_k127_6444486_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 388.0
HKD2_k127_6444486_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000727 213.0
HKD2_k127_6444486_6 FMN_bind - - - 0.00000000000000000000000001563 115.0
HKD2_k127_6475211_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.244e-273 862.0
HKD2_k127_6475211_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 283.0
HKD2_k127_6475211_2 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007935 273.0
HKD2_k127_6475211_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001735 257.0
HKD2_k127_6475211_4 Protein of unknown function (DUF523) - - - 0.00000000000000000000000000000000000000000002276 165.0
HKD2_k127_6475211_5 Peptidase, U32 family K08303 - - 0.000000000000000000000000000000000000000001487 169.0
HKD2_k127_6485934_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 540.0
HKD2_k127_6485934_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 518.0
HKD2_k127_6485934_10 Domain of unknown function (DUF4342) - - - 0.00000000000000000000000000000000009142 138.0
HKD2_k127_6485934_11 Protein of unknown function (DUF445) - - - 0.00000000000000001039 87.0
HKD2_k127_6485934_2 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 433.0
HKD2_k127_6485934_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 410.0
HKD2_k127_6485934_4 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 353.0
HKD2_k127_6485934_5 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 296.0
HKD2_k127_6485934_6 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009067 246.0
HKD2_k127_6485934_7 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000006116 215.0
HKD2_k127_6485934_8 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000008755 219.0
HKD2_k127_6485934_9 prohibitin homologues - - - 0.0000000000000000000000000000000000000004475 150.0
HKD2_k127_6487633_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1377.0
HKD2_k127_6487633_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 9.116e-315 974.0
HKD2_k127_6487633_10 Peptidase, M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 320.0
HKD2_k127_6487633_11 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 306.0
HKD2_k127_6487633_12 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 288.0
HKD2_k127_6487633_13 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 286.0
HKD2_k127_6487633_14 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006964 279.0
HKD2_k127_6487633_15 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000208 252.0
HKD2_k127_6487633_16 PFAM t-RNA-binding domain protein K06878 - - 0.00000000000000000000000000000000000000000000000000002059 189.0
HKD2_k127_6487633_17 Ferric uptake regulator family K02076,K03711 - - 0.00000000000000000000000000000000001027 140.0
HKD2_k127_6487633_18 PucR C-terminal helix-turn-helix domain K02647 - - 0.000000000000000000000000000002447 132.0
HKD2_k127_6487633_19 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000003936 111.0
HKD2_k127_6487633_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 508.0
HKD2_k127_6487633_20 Protein of unknown function (DUF1450) - - - 0.000000000000000000008799 93.0
HKD2_k127_6487633_21 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000002118 71.0
HKD2_k127_6487633_3 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 495.0
HKD2_k127_6487633_4 PFAM AIR synthase related protein K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 404.0
HKD2_k127_6487633_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 376.0
HKD2_k127_6487633_6 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 369.0
HKD2_k127_6487633_7 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 334.0
HKD2_k127_6487633_8 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 335.0
HKD2_k127_6487633_9 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 325.0
HKD2_k127_6492641_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 366.0
HKD2_k127_6492641_1 peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003217 277.0
HKD2_k127_6492641_2 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.000000000000000000000000000122 115.0
HKD2_k127_64929_0 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 470.0
HKD2_k127_64929_1 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 448.0
HKD2_k127_64929_2 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 355.0
HKD2_k127_64929_3 Putative undecaprenyl diphosphate synthase K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 342.0
HKD2_k127_64929_4 Domain of unknown function (DUF5050) - - - 0.000000000000000000000000000000000000000000000000000000000000003662 228.0
HKD2_k127_64929_5 Yip1 domain - - - 0.0000003362 56.0
HKD2_k127_6500893_0 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 466.0
HKD2_k127_6500893_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000001734 238.0
HKD2_k127_6512779_0 Belongs to the glutaminase family K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 365.0
HKD2_k127_6517347_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1039.0
HKD2_k127_6517347_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5.713e-274 857.0
HKD2_k127_6517347_10 DUF based on E. rectale Gene description (DUF3880) - - - 0.00000000000000000000000000000000000000000000000000000000002331 211.0
HKD2_k127_6517347_2 Belongs to the glycosyl hydrolase 13 family K01200 - 3.2.1.41 3.645e-272 849.0
HKD2_k127_6517347_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 2.892e-218 685.0
HKD2_k127_6517347_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 1.475e-212 666.0
HKD2_k127_6517347_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 542.0
HKD2_k127_6517347_6 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 460.0
HKD2_k127_6517347_7 Glucose-1-phosphate adenylyltransferase, GlgD subunit K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 437.0
HKD2_k127_6517347_8 DUF based on E. rectale Gene description (DUF3880) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 439.0
HKD2_k127_6517347_9 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 403.0
HKD2_k127_6545969_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 5.845e-268 833.0
HKD2_k127_6545969_1 PFAM Protein synthesis factor, GTP-binding K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 509.0
HKD2_k127_6545969_2 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 308.0
HKD2_k127_6545969_3 Ferric uptake regulator, Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000005678 213.0
HKD2_k127_6547655_0 Domain of unknown function (DUF4438) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 397.0
HKD2_k127_6547655_1 hydrolase, family 3 K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000001046 183.0
HKD2_k127_6547655_2 Transcriptional Coactivator p15 (PC4) - - - 0.000000000000000000000000000002083 121.0
HKD2_k127_6555144_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.91e-284 887.0
HKD2_k127_6555144_1 flagellar basal body K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 461.0
HKD2_k127_6555144_10 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000001178 223.0
HKD2_k127_6555144_11 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000804 208.0
HKD2_k127_6555144_12 flagellar operon protein - - - 0.00000000000000000000000000001483 121.0
HKD2_k127_6555144_13 Flagellar biosynthetic protein FliQ K02420 - - 0.00000000000000000000000008708 108.0
HKD2_k127_6555144_14 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000000000001071 114.0
HKD2_k127_6555144_15 PFAM Flagellar hook-length control K02414 - - 0.0000000000000000000000008213 110.0
HKD2_k127_6555144_16 Flagellar protein (FlbD) K02385 - - 0.000000000000002767 77.0
HKD2_k127_6555144_17 PFAM type IV pilus assembly PilZ - - - 0.00000000000007724 79.0
HKD2_k127_6555144_18 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000003476 69.0
HKD2_k127_6555144_19 Flagellar biosynthesis protein, FliO K02418 - - 0.000001323 57.0
HKD2_k127_6555144_2 flagellar motor switch protein K02417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 417.0
HKD2_k127_6555144_3 flagellar motor switch protein FliM K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 384.0
HKD2_k127_6555144_4 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401,K13820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 374.0
HKD2_k127_6555144_5 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 323.0
HKD2_k127_6555144_6 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 315.0
HKD2_k127_6555144_7 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 306.0
HKD2_k127_6555144_8 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 308.0
HKD2_k127_6555144_9 Flagellar biosynthetic protein FliR K02421 - - 0.000000000000000000000000000000000000000000000000000000000000000000004024 243.0
HKD2_k127_6559576_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 552.0
HKD2_k127_6559576_1 transcriptional regulator (AraC family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 464.0
HKD2_k127_6559576_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000008742 227.0
HKD2_k127_6559576_3 PAS domain K09155 - - 0.00000000000000000000000000000000000000000000000000000000001837 210.0
HKD2_k127_6559576_4 Psort location Cytoplasmic, score K07814 - - 0.00000000000000000000000000000000000000000000000000000004144 209.0
HKD2_k127_6572344_0 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006371 554.0
HKD2_k127_6572344_1 smart pdz dhr glgf K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 378.0
HKD2_k127_6572344_2 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 317.0
HKD2_k127_6572344_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000001172 177.0
HKD2_k127_6576508_0 Belongs to the glycosyl hydrolase 43 family K01198 - 3.2.1.37 4.591e-252 785.0
HKD2_k127_6576508_1 solute-binding protein - - - 1.632e-242 756.0
HKD2_k127_6576508_2 helix_turn _helix lactose operon repressor K02529,K03604 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 485.0
HKD2_k127_6576508_3 PFAM Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 484.0
HKD2_k127_6576508_4 PFAM Binding-protein-dependent transport system inner membrane component K02026,K10242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 434.0
HKD2_k127_6576795_0 ABC transporter permease K02011 - - 6.849e-239 752.0
HKD2_k127_6576795_1 ATPases associated with a variety of cellular activities K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 462.0
HKD2_k127_6576795_2 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 412.0
HKD2_k127_6576795_3 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000004069 65.0
HKD2_k127_6582145_0 Asparagine synthase K01953 - 6.3.5.4 1.329e-285 888.0
HKD2_k127_6582145_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 563.0
HKD2_k127_6582145_10 Transglutaminase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001682 258.0
HKD2_k127_6582145_11 HD domain - - - 0.00000000000000000000000000000000000000000000000000000001067 203.0
HKD2_k127_6582145_12 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000004759 181.0
HKD2_k127_6582145_13 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000006233 117.0
HKD2_k127_6582145_14 Domain of unknown function (DUF1858) - - - 0.00000000000000000000000009263 108.0
HKD2_k127_6582145_15 Peptidase S24-like K13280 - 3.4.21.89 0.00000000000000000007996 94.0
HKD2_k127_6582145_16 Glutaredoxin-related protein - - - 0.00000000000002011 75.0
HKD2_k127_6582145_2 Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 533.0
HKD2_k127_6582145_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 505.0
HKD2_k127_6582145_4 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 424.0
HKD2_k127_6582145_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 405.0
HKD2_k127_6582145_6 L-serine dehydratase, iron-sulfur-dependent, alpha subunit K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 352.0
HKD2_k127_6582145_7 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 349.0
HKD2_k127_6582145_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 295.0
HKD2_k127_6582145_9 L-serine dehydratase, iron-sulfur-dependent, beta subunit K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000008355 263.0
HKD2_k127_6588126_0 Belongs to the UPF0061 (SELO) family - - - 4.718e-245 764.0
HKD2_k127_6588126_1 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 467.0
HKD2_k127_6588126_2 Psort location CytoplasmicMembrane, score K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 394.0
HKD2_k127_6588126_3 Peptidase family C69 K14358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 351.0
HKD2_k127_6588126_4 PFAM Bacterial regulatory proteins, gntR family - - - 0.000000000000000000000000000000000000000000000004543 175.0
HKD2_k127_6588126_5 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000002808 156.0
HKD2_k127_6588126_6 B12 binding domain - - - 0.000003196 50.0
HKD2_k127_6596158_0 Required for chromosome condensation and partitioning K03529 - - 1.415e-253 823.0
HKD2_k127_6596158_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 586.0
HKD2_k127_6596158_10 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002825 251.0
HKD2_k127_6596158_11 stage V sporulation protein S K06416 - - 0.0000000000000000000000000000000000002105 142.0
HKD2_k127_6596158_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000005539 114.0
HKD2_k127_6596158_13 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000001042 61.0
HKD2_k127_6596158_2 enoyl-(acyl-carrier-protein) reductase II K02371 - 1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 458.0
HKD2_k127_6596158_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 442.0
HKD2_k127_6596158_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 404.0
HKD2_k127_6596158_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 399.0
HKD2_k127_6596158_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 383.0
HKD2_k127_6596158_7 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 356.0
HKD2_k127_6596158_8 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 321.0
HKD2_k127_6596158_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002298 258.0
HKD2_k127_6603469_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 488.0
HKD2_k127_6603469_1 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 403.0
HKD2_k127_6603469_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 355.0
HKD2_k127_6603469_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 298.0
HKD2_k127_6603469_4 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000005289 250.0
HKD2_k127_6603469_5 PFAM PfkB domain protein K00852,K16328 - 2.7.1.15,2.7.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000001018 256.0
HKD2_k127_6603469_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000001363 183.0
HKD2_k127_6603602_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01666,K18365 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0008701,GO:0016829,GO:0016830,GO:0016833,GO:0030312,GO:0044464,GO:0071944 4.1.3.39,4.1.3.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 539.0
HKD2_k127_6603602_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 452.0
HKD2_k127_6603602_2 Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds K04073 - 1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 454.0
HKD2_k127_6603602_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 315.0
HKD2_k127_6603602_4 BFD-like 2Fe-2S binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001766 244.0
HKD2_k127_6603602_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000002084 93.0
HKD2_k127_6644033_0 2-hydroxycarboxylate transporter family K11616 - - 1.368e-214 673.0
HKD2_k127_6644033_1 malic enzyme K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 595.0
HKD2_k127_6644033_2 signal transduction histidine kinase regulating citrate malate metabolism K02476,K11614,K11691 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 554.0
HKD2_k127_6644033_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 436.0
HKD2_k127_6644033_4 transcriptional regulatory protein K02475,K11615,K11692,K11712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 310.0
HKD2_k127_6644033_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003149 270.0
HKD2_k127_6663192_0 Psort location - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004803 295.0
HKD2_k127_6663192_1 Type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008736 263.0
HKD2_k127_6663192_2 Flp pilus assembly protein TadB K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006296 246.0
HKD2_k127_6663192_3 Type II IV secretion system protein K02283 - - 0.0000000000000000000000000007984 113.0
HKD2_k127_6663192_4 - - - - 0.00000000000000007075 81.0
HKD2_k127_6663192_5 Pilus assembly protein TadE - - - 0.0000000000000001257 88.0
HKD2_k127_6668596_0 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 9.363e-197 615.0
HKD2_k127_6668596_1 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 460.0
HKD2_k127_6668669_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1143.0
HKD2_k127_6668669_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 2.077e-291 910.0
HKD2_k127_6668669_10 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000002757 173.0
HKD2_k127_6668669_11 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000001945 109.0
HKD2_k127_6668669_2 dihydroorotate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 546.0
HKD2_k127_6668669_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 548.0
HKD2_k127_6668669_4 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K20810 - 3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 540.0
HKD2_k127_6668669_5 molybdopterin dehydrogenase, FAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001018 286.0
HKD2_k127_6668669_6 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000412 266.0
HKD2_k127_6668669_7 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000000000000000000000009615 232.0
HKD2_k127_6668669_8 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000003615 209.0
HKD2_k127_6668669_9 [2Fe-2S] binding domain K03518,K20446 - 1.17.1.5,1.2.5.3 0.0000000000000000000000000000000000000000000000000009051 187.0
HKD2_k127_6684207_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K02851 - 2.7.8.33,2.7.8.35,5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 482.0
HKD2_k127_6684207_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 369.0
HKD2_k127_6684207_2 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 352.0
HKD2_k127_6684207_3 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 323.0
HKD2_k127_6684207_4 PFAM Zinc iron permease K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000274 278.0
HKD2_k127_6684207_5 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000233 223.0
HKD2_k127_6684207_6 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000002947 223.0
HKD2_k127_6684207_7 Transposase IS200 like - - - 0.000000000000000000000000000000000001085 144.0
HKD2_k127_6684207_8 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000000000000000000001026 132.0
HKD2_k127_6688129_0 PFAM response regulator receiver K07720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 558.0
HKD2_k127_6688129_1 Histidine kinase K07718 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 412.0
HKD2_k127_6697312_0 C4-dicarboxylate anaerobic carrier - - - 1.302e-272 848.0
HKD2_k127_6697312_1 Polysaccharide biosynthesis C-terminal domain - - - 1.079e-217 681.0
HKD2_k127_6697312_10 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000004489 223.0
HKD2_k127_6697312_11 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000006544 187.0
HKD2_k127_6697312_12 Domain of unknown function (DUF4363) - - - 0.000000000000000000000000000000000000000000001899 167.0
HKD2_k127_6697312_2 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 572.0
HKD2_k127_6697312_3 Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation K01305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 536.0
HKD2_k127_6697312_4 Alpha beta hydrolase K00433,K01055 - 1.11.1.10,3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 432.0
HKD2_k127_6697312_5 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 398.0
HKD2_k127_6697312_6 S1, RNA binding domain K00243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 385.0
HKD2_k127_6697312_7 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 317.0
HKD2_k127_6697312_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001268 289.0
HKD2_k127_6697312_9 Iron-storage protein K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000000000000000000003697 224.0
HKD2_k127_6701457_0 SMART AAA ATPase K06390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 351.0
HKD2_k127_6701457_1 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000007713 169.0
HKD2_k127_6701457_2 Stage III sporulation protein AD K06393 - - 0.000000000000000000000000000000000000000003742 158.0
HKD2_k127_6701457_3 Stage III sporulation protein AB (spore_III_AB) K06391 - - 0.00000000000000000000000000000000003617 140.0
HKD2_k127_6701457_4 TIGRFAM stage III sporulation protein AC K06392 - - 0.0000000000000000007161 87.0
HKD2_k127_6713541_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 6.185e-219 682.0
HKD2_k127_6713541_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 8.996e-218 681.0
HKD2_k127_6713541_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 519.0
HKD2_k127_6713541_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 476.0
HKD2_k127_6713541_4 CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 378.0
HKD2_k127_6713541_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 347.0
HKD2_k127_6713541_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 301.0
HKD2_k127_6713541_8 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000007663 79.0
HKD2_k127_6726801_0 PFAM Orn Lys Arg decarboxylase major K01582,K01585 - 4.1.1.18,4.1.1.19 5.716e-237 740.0
HKD2_k127_6726801_1 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 1.574e-209 678.0
HKD2_k127_6726801_10 stage V sporulation protein AC K06405 - - 0.0000000000000000000000000000000000000000000000000000000009688 204.0
HKD2_k127_6726801_11 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition K06379 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001567 197.0
HKD2_k127_6726801_12 TIGRFAM stage V sporulation protein AE K06407 - - 0.0000000000000000000000000000000000000000000000000008708 184.0
HKD2_k127_6726801_13 sporulation protein YunB - - - 0.0000000000000000000000000000000000000000000000002299 184.0
HKD2_k127_6726801_14 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000001524 131.0
HKD2_k127_6726801_15 Anti-sigma F factor antagonist K06378 - - 0.000000000000000000000000007666 113.0
HKD2_k127_6726801_16 - - - - 0.00000001835 55.0
HKD2_k127_6726801_2 L-asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 511.0
HKD2_k127_6726801_3 PFAM Stage V sporulation AD K06406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 491.0
HKD2_k127_6726801_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 446.0
HKD2_k127_6726801_5 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 402.0
HKD2_k127_6726801_6 PFAM Glycosyltransferase family 28 C-terminal domain K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 330.0
HKD2_k127_6726801_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 297.0
HKD2_k127_6726801_8 Stage V sporulation protein AE1 K06407 - - 0.00000000000000000000000000000000000000000000000000000000000001835 220.0
HKD2_k127_6726801_9 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.0000000000000000000000000000000000000000000000000000000000006253 213.0
HKD2_k127_6735068_0 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000064 260.0
HKD2_k127_6735068_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000004124 232.0
HKD2_k127_6735068_2 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0000000000000000009811 90.0
HKD2_k127_6736492_0 C4-dicarboxylate anaerobic carrier - - - 4.479e-233 732.0
HKD2_k127_6736492_1 Cupin 2, conserved barrel domain protein K21700 - - 0.00000000000000000000000005554 108.0
HKD2_k127_6738616_0 SPFH domain / Band 7 family - - - 0.0 1163.0
HKD2_k127_6738616_1 Penicillin-binding Protein dimerisation domain K03587,K08384 - 3.4.16.4 8.852e-280 870.0
HKD2_k127_6738616_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000005416 224.0
HKD2_k127_6738616_11 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000000000008576 194.0
HKD2_k127_6738616_12 Domain of unknown function (DUF1904) - - - 0.0000000000000000000000000000000000000003389 151.0
HKD2_k127_6738616_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000002294 125.0
HKD2_k127_6738616_14 Sigma-70 region 2 - - - 0.0000000002799 64.0
HKD2_k127_6738616_2 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 1.931e-269 835.0
HKD2_k127_6738616_3 Belongs to the beta-eliminating lyase family K01667 - 4.1.99.1 3.503e-257 797.0
HKD2_k127_6738616_4 Methyltransferase - - - 1.264e-195 616.0
HKD2_k127_6738616_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 578.0
HKD2_k127_6738616_6 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 546.0
HKD2_k127_6738616_7 HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 338.0
HKD2_k127_6738616_8 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 304.0
HKD2_k127_6738616_9 Participates in the control of copper homeostasis K06201 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 295.0
HKD2_k127_6740692_0 ATPase histidine kinase DNA gyrase B HSP90 domain protein K07652 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 457.0
HKD2_k127_6740692_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 366.0
HKD2_k127_6740692_2 response regulator receiver K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 328.0
HKD2_k127_6740692_3 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000000000000007669 223.0
HKD2_k127_6740692_4 aminopeptidase N - - - 0.00000000000000000000000000000000000000001674 163.0
HKD2_k127_6740692_5 Putative regulatory protein - - - 0.0000000000000001089 81.0
HKD2_k127_6744144_0 carboxyltransferase K01571 - 4.1.1.3 2.973e-225 705.0
HKD2_k127_6744144_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 518.0
HKD2_k127_6744144_10 - - - - 0.000000000000000000000000000000000000000000000000000001787 194.0
HKD2_k127_6744144_11 TIGRFAM sporulation protein YtfJ - - - 0.00000000000000000000000000000000000002149 147.0
HKD2_k127_6744144_12 Best Blastp hit gi 7431974 pir F72256 'Fe-hydrogenase, subunit beta - Thermotoga maritima (strain MSB8)' gi 2865516 gb AAC02685.1 (AF044577) Fe-hydrogenase beta subunit Thermotoga maritima gi 4981989 gb AAD36495.1 AE001794_11 '(AE001794) Fe-hydrogenase, subunit beta Thermotoga maritima ', score K00176 - 1.2.7.3 0.0000000000000000000005141 97.0
HKD2_k127_6744144_13 Protein of unknown function (DUF2953) - - - 0.000000000005194 74.0
HKD2_k127_6744144_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 444.0
HKD2_k127_6744144_3 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 426.0
HKD2_k127_6744144_4 transcriptional regulator, RpiR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 388.0
HKD2_k127_6744144_5 PFAM peptidase S11, D-alanyl-D-alanine carboxypeptidase K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 361.0
HKD2_k127_6744144_6 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 293.0
HKD2_k127_6744144_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008988 282.0
HKD2_k127_6744144_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001289 263.0
HKD2_k127_6744144_9 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000005283 224.0
HKD2_k127_6749903_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 430.0
HKD2_k127_6749903_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341 344.0
HKD2_k127_6749903_2 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865 298.0
HKD2_k127_6749903_3 Alpha beta K06889 - - 0.00006212 48.0
HKD2_k127_6750744_0 hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 311.0
HKD2_k127_6750744_1 FMN binding - - - 0.0000000000000000000000000000000000000000000001956 173.0
HKD2_k127_6750744_2 HD domain - - - 0.000000000000000000000000000000000000000000002568 170.0
HKD2_k127_6750744_3 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000008279 122.0
HKD2_k127_6750744_4 Acetyltransferase (GNAT) domain - - - 0.000000000000472 69.0
HKD2_k127_6750744_5 CAAX protease self-immunity K07052 - - 0.00006775 53.0
HKD2_k127_6767174_0 TIGRFAM ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent K00525 - 1.17.4.1 2.793e-294 912.0
HKD2_k127_6767174_1 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 408.0
HKD2_k127_6767927_0 import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 571.0
HKD2_k127_6767927_1 Extracellular solute-binding protein K17318 - - 0.000000000000000000000000000000182 124.0
HKD2_k127_6807272_0 Thi4 family - - - 0.0 1474.0
HKD2_k127_6807272_1 Elongation factor Tu GTP binding domain - - - 0.0 1409.0
HKD2_k127_6807272_10 DMT(Drug metabolite transporter) superfamily permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 475.0
HKD2_k127_6807272_11 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 473.0
HKD2_k127_6807272_12 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 392.0
HKD2_k127_6807272_13 ABC-2 family transporter protein K01421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 344.0
HKD2_k127_6807272_14 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 328.0
HKD2_k127_6807272_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 310.0
HKD2_k127_6807272_16 Protein of unknown function (DUF2975) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001035 253.0
HKD2_k127_6807272_17 Transglycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005158 245.0
HKD2_k127_6807272_18 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000007225 206.0
HKD2_k127_6807272_19 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.000000000000000000000000000000000000000000000000000004043 191.0
HKD2_k127_6807272_2 ABC transporter K06158 - - 1e-323 996.0
HKD2_k127_6807272_20 Transcriptional regulator C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000129 194.0
HKD2_k127_6807272_21 Putative ABC-transporter type IV - - - 0.0000000000000000000000000000000000000000000000000001871 188.0
HKD2_k127_6807272_22 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000113 186.0
HKD2_k127_6807272_23 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000000000000000005302 159.0
HKD2_k127_6807272_24 Transcriptional regulator K07727 - - 0.0000000000000000000000000000000002786 132.0
HKD2_k127_6807272_25 FMN_bind - - - 0.000000000000000000000000000004233 123.0
HKD2_k127_6807272_26 PspC domain K03973 - - 0.00000000000000000001828 94.0
HKD2_k127_6807272_27 - - - - 0.000000000000002971 76.0
HKD2_k127_6807272_3 oligopeptide transporter, OPT family - - - 2.017e-308 955.0
HKD2_k127_6807272_4 ABC transporter K18231 - - 1.387e-240 754.0
HKD2_k127_6807272_5 Psort location CytoplasmicMembrane, score K07003 - - 1.54e-221 707.0
HKD2_k127_6807272_6 FAD dependent oxidoreductase K00244 - 1.3.5.4 3.657e-220 691.0
HKD2_k127_6807272_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 1.436e-197 618.0
HKD2_k127_6807272_8 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 588.0
HKD2_k127_6807272_9 K13530 AraC family transcriptional regulator, regulatory protein of adaptative response methylphosphotriester-DNA alkyltransferase methyltransferase K13653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 507.0
HKD2_k127_6807482_0 MazG family K02428,K02499 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 559.0
HKD2_k127_6807482_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000006515 138.0
HKD2_k127_6807482_2 S4 domain protein - - - 0.00000000004777 63.0
HKD2_k127_68096_0 aminoacyl-histidine dipeptidase K01270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 414.0
HKD2_k127_68096_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 287.0
HKD2_k127_6822531_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 289.0
HKD2_k127_6822531_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000001544 109.0
HKD2_k127_6834732_0 CotH protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 529.0
HKD2_k127_6834732_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000003395 214.0
HKD2_k127_6944010_0 Mate efflux family protein - - - 6.085e-197 622.0
HKD2_k127_6944010_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001076 241.0
HKD2_k127_6944010_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000001176 177.0
HKD2_k127_6944010_3 bis(5'-adenosyl)-triphosphatase activity - - - 0.000000000000000000000000000000002946 131.0
HKD2_k127_6944010_4 Helix-turn-helix XRE-family like proteins K16868 - 2.1.1.265 0.0004353 44.0
HKD2_k127_7009180_0 L-ribulose-5-phosphate 4-epimerase K01628,K03077 - 4.1.2.17,5.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001531 253.0
HKD2_k127_7009180_1 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000006818 210.0
HKD2_k127_7009180_2 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000001111 168.0
HKD2_k127_7009180_3 - - - - 0.00000000000000009004 81.0
HKD2_k127_7063870_0 aconitate hydratase K01681 - 4.2.1.3 9.268e-281 875.0
HKD2_k127_7063870_1 phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 525.0
HKD2_k127_7063870_10 Glycerol-3-phosphate cytidylyltransferase K00980 - 2.7.7.39 0.00000000000000000000000000000000002451 136.0
HKD2_k127_7063870_11 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000005147 77.0
HKD2_k127_7063870_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 488.0
HKD2_k127_7063870_3 Isocitrate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 440.0
HKD2_k127_7063870_4 Protein of unknown function (DUF4256) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 321.0
HKD2_k127_7063870_5 phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005072 274.0
HKD2_k127_7063870_6 Capsular exopolysaccharide family - - - 0.0000000000000000000000000000000000000000000000000000000000002939 218.0
HKD2_k127_7063870_7 biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000009698 216.0
HKD2_k127_7063870_8 biosynthesis protein K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000002169 185.0
HKD2_k127_7063870_9 Cell envelope-related transcriptional attenuator domain - - - 0.0000000000000000000000000000000000000000000001166 179.0
HKD2_k127_7065894_0 Belongs to the TelA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 401.0
HKD2_k127_7065894_1 acetyltransferase K18566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 290.0
HKD2_k127_7065894_2 Lipid kinase K07029 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000000000001703 208.0
HKD2_k127_7065894_3 TSCPD domain - - - 0.00000000000000000000000003579 109.0
HKD2_k127_7074100_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 420.0
HKD2_k127_7074100_1 Family of unknown function (DUF5317) - - - 0.0000000000000000000000000000000000000000000009051 171.0
HKD2_k127_7125485_0 Belongs to the MurCDEF family K03802 - 6.3.2.29,6.3.2.30 4.059e-244 771.0
HKD2_k127_7125485_1 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000002569 118.0
HKD2_k127_7178083_0 Transcriptional regulator, LacI family K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 421.0
HKD2_k127_7178083_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000001399 175.0
HKD2_k127_7178083_2 Uncharacterized conserved protein (DUF2164) - - - 0.0000000000000000000000004305 106.0
HKD2_k127_7292819_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.163e-237 758.0
HKD2_k127_7292819_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 578.0
HKD2_k127_7292819_10 Phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000009232 233.0
HKD2_k127_7292819_11 thiamine pyrophosphokinase K00949 - 2.7.6.2 0.000000000000000000000000000000000000000000000000000000001292 207.0
HKD2_k127_7292819_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000001824 203.0
HKD2_k127_7292819_13 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000008618 104.0
HKD2_k127_7292819_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 481.0
HKD2_k127_7292819_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 409.0
HKD2_k127_7292819_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 360.0
HKD2_k127_7292819_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 310.0
HKD2_k127_7292819_6 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 290.0
HKD2_k127_7292819_7 zinc metallopeptidase K06973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005427 272.0
HKD2_k127_7292819_8 Protein of unknown function (DUF2812) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001651 274.0
HKD2_k127_7292819_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000009051 248.0
HKD2_k127_7435599_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 347.0
HKD2_k127_7435599_1 PFAM Response regulator receiver domain K07775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 287.0
HKD2_k127_7435599_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000002641 51.0
HKD2_k127_7435599_3 Best Blastp hit gi 98474 pir A38447 oligopeptide ABC transport system substrate-binding protein oppA precursor - Bacillus subtilis gi 143603 gb AAA62687.1 (M57689) sporulation protein Bacillus subtilis gi 2633497 emb CAB13000.1 (Z99110) oligopeptide ABC transporter (binding protein) Bacillus subtilis , score K15580 - - 0.0002187 46.0
HKD2_k127_74630_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1375.0
HKD2_k127_7502790_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0 1127.0
HKD2_k127_7502790_1 Phosphate acetyl/butaryl transferase K00634 - 2.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 507.0
HKD2_k127_7502790_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000001954 123.0
HKD2_k127_7502790_4 - - - - 0.0000000000000005283 77.0
HKD2_k127_7533673_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0 1020.0
HKD2_k127_7533673_1 Elongation factor G C-terminus K06207 - - 1.566e-210 658.0
HKD2_k127_7533673_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 387.0
HKD2_k127_7533673_3 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 281.0
HKD2_k127_7533673_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000000000000000000000000000000003458 233.0
HKD2_k127_7533673_5 Belongs to the UPF0297 family - - - 0.00000000000000000000000000000000000000000000001795 171.0
HKD2_k127_7533673_6 Belongs to the UPF0473 family - - - 0.000000000000000000000000000000000001722 139.0
HKD2_k127_7533893_0 Ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 9.098e-299 924.0
HKD2_k127_7533893_1 ABC transporter K06147,K11085,K18888 - - 6.482e-285 885.0
HKD2_k127_7533893_2 ABC transporter transmembrane region K06147 - - 3.034e-254 796.0
HKD2_k127_7533893_3 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04068 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000007567 220.0
HKD2_k127_75765_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 4.107e-217 685.0
HKD2_k127_75765_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 554.0
HKD2_k127_75765_10 EamA-like transporter family - - - 0.00000002815 55.0
HKD2_k127_75765_2 DbpA RNA binding domain K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 512.0
HKD2_k127_75765_3 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 449.0
HKD2_k127_75765_4 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 432.0
HKD2_k127_75765_5 Helix-turn-helix domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 306.0
HKD2_k127_75765_6 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004646 254.0
HKD2_k127_75765_7 Lysine exporter protein LysE YggA K11249 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001047 252.0
HKD2_k127_75765_8 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000002633 141.0
HKD2_k127_75765_9 - - - - 0.00000000000000000000003688 102.0
HKD2_k127_7603265_0 - - - - 0.00000000000000000000000000000000000000000000000000000397 197.0
HKD2_k127_7603265_1 NUMOD4 motif - - - 0.0000000000000000000000000000000000006078 145.0
HKD2_k127_7603265_2 Phage replisome organizer - - - 0.00000000000003038 74.0
HKD2_k127_7662757_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 467.0
HKD2_k127_7662757_1 SMART phosphoesterase PHP domain protein K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 308.0
HKD2_k127_7662757_2 PspC domain K03973 - - 0.0000000000000000003826 90.0
HKD2_k127_7692768_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004029 271.0
HKD2_k127_7692768_1 domain protein - - - 0.000000002171 70.0
HKD2_k127_7697520_0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 4.95e-282 888.0
HKD2_k127_7697520_1 Amino acid permease K03294 - - 4.36e-213 669.0
HKD2_k127_7697520_10 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000003235 208.0
HKD2_k127_7697520_11 - - - - 0.000000000000000000000000000000000000000000000006435 174.0
HKD2_k127_7697520_12 - - - - 0.000000000000000000000000000000000008132 145.0
HKD2_k127_7697520_13 6-pyruvoyl tetrahydropterin synthase - - - 0.00000000000000000000000000000000001147 139.0
HKD2_k127_7697520_14 - - - - 0.000000000000000000000000000002683 123.0
HKD2_k127_7697520_15 Zinc transporter ZupT K07238 - - 0.000000000000000000002561 93.0
HKD2_k127_7697520_16 GtrA-like protein - - - 0.0001663 49.0
HKD2_k127_7697520_2 PFAM sulfatase - - - 2.792e-206 661.0
HKD2_k127_7697520_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 580.0
HKD2_k127_7697520_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 577.0
HKD2_k127_7697520_5 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 448.0
HKD2_k127_7697520_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 366.0
HKD2_k127_7697520_7 Excinuclease ABC C subunit domain protein K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 302.0
HKD2_k127_7697520_8 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004905 256.0
HKD2_k127_7697520_9 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000007353 227.0
HKD2_k127_7706405_0 phenylalanyl-tRNA synthetase (beta subunit) K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 4.197e-266 839.0
HKD2_k127_7706405_1 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 562.0
HKD2_k127_7706405_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 495.0
HKD2_k127_7706405_3 peptidase U62, modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 491.0
HKD2_k127_7746137_0 glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 0.0 1259.0
HKD2_k127_7746137_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002615 280.0
HKD2_k127_7746137_2 PFAM helix-turn-helix HxlR type - - - 0.000000000000000000000000000000000000000000000000004804 184.0
HKD2_k127_7746137_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000003786 140.0
HKD2_k127_7746349_0 Cytidylyltransferase-like - - - 0.0 1817.0
HKD2_k127_7746349_1 lactate/malate dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 464.0
HKD2_k127_7746349_2 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 364.0
HKD2_k127_7746349_3 Belongs to the pseudouridine synthase RsuA family K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 320.0
HKD2_k127_7746349_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000004052 126.0
HKD2_k127_7746349_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000001817 79.0
HKD2_k127_7746349_6 Belongs to the peptidase S8 family - - - 0.000001657 51.0
HKD2_k127_7785888_0 Belongs to the ClpA ClpB family K03696 - - 1.263e-316 972.0
HKD2_k127_7813418_0 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 340.0
HKD2_k127_7813418_1 TIGRFAM Diguanylate cyclase K18967 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001123 285.0
HKD2_k127_7813418_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001133 269.0
HKD2_k127_7813418_3 Alpha beta hydrolase K00433,K01055 - 1.11.1.10,3.1.1.24 0.0000000000000000000000000000000000000000000002365 168.0
HKD2_k127_7820627_0 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 406.0
HKD2_k127_7820627_1 Recombinase zinc beta ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 387.0
HKD2_k127_7820627_2 Bacterial protein of unknown function (DUF881) - - - 0.000000000000000000000000000000000000000000000000007331 188.0
HKD2_k127_7820627_3 Bacterial protein of unknown function (DUF881) - - - 0.00000000000000000000000000000000000000000001019 171.0
HKD2_k127_7820627_4 small basic protein - - - 0.000000000000000000000000000000000000000002381 158.0
HKD2_k127_7820627_5 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000002202 135.0
HKD2_k127_7820627_6 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.000000000000004266 77.0
HKD2_k127_7820627_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000003991 60.0
HKD2_k127_7820627_8 Helix-turn-helix XRE-family like proteins - - - 0.000003538 56.0
HKD2_k127_7823698_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 593.0
HKD2_k127_7823698_1 Belongs to the UPF0348 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 352.0
HKD2_k127_7823698_2 TIGRFAM sporulation integral membrane protein YlbJ - - - 0.00000000000000000000000000000000000000000000000000000000000009222 221.0
HKD2_k127_7823698_3 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000005495 108.0
HKD2_k127_7823698_4 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000008504 94.0
HKD2_k127_7835434_0 Glycosyltransferase 36 associated - - - 0.0 1615.0
HKD2_k127_7835434_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 2.266e-199 623.0
HKD2_k127_7835434_2 Xylose isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 580.0
HKD2_k127_7835434_3 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 582.0
HKD2_k127_7835434_4 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002165 263.0
HKD2_k127_7835434_5 Desulfoferrodoxin ferrous iron-binding K05919 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016721,GO:0019430,GO:0022900,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.2 0.000000000000000000000000000000000000000000000000000000000000000009552 226.0
HKD2_k127_7835434_6 Domain of unknown function (DUF368) K08974 - - 0.0000000000000000000000000000000000000000000000000000000000002771 214.0
HKD2_k127_783674_0 Fatty acid K21576 - 1.21.4.2,1.21.4.3,1.21.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 480.0
HKD2_k127_783674_1 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 285.0
HKD2_k127_7844195_0 branched-chain amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 302.0
HKD2_k127_7844195_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000001816 199.0
HKD2_k127_7844195_2 - - - - 0.0000000000000000000000000000000000000000000000003029 183.0
HKD2_k127_7844195_3 branched-chain amino acid - - - 0.0000000000000000000000005133 107.0
HKD2_k127_7844195_4 - - - - 0.000001792 50.0
HKD2_k127_7874535_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 489.0
HKD2_k127_7874535_1 Belongs to the ABC transporter superfamily K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 474.0
HKD2_k127_7874535_2 PFAM binding-protein-dependent transport systems inner membrane component K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 417.0
HKD2_k127_7874535_3 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 406.0
HKD2_k127_7874535_4 binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 355.0
HKD2_k127_7874535_5 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000001017 191.0
HKD2_k127_7895892_0 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 4.548e-251 779.0
HKD2_k127_7895892_1 PFAM Peptidase M1, membrane alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 524.0
HKD2_k127_7895892_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000001309 224.0
HKD2_k127_7895892_3 domain, Protein - - - 0.0000000000000000000000000000000000000000000242 183.0
HKD2_k127_7895892_4 Cysteine-rich small domain K07162 - - 0.000000000000000000000000000000000000000009834 154.0
HKD2_k127_7895892_5 Belongs to the glycosyl hydrolase 43 family - - - 0.00000000000000000000000000000000000000001217 175.0
HKD2_k127_7895892_6 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000002342 119.0
HKD2_k127_7895892_7 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000002787 109.0
HKD2_k127_7895892_8 repeat protein - - - 0.000000000000000002372 100.0
HKD2_k127_7919599_0 TIGRFAM PAS domain S-box - - - 8.13e-205 663.0
HKD2_k127_7919599_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 304.0
HKD2_k127_7919599_2 - - - - 0.00000000000000000000001128 101.0
HKD2_k127_7925301_0 PFAM D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein, D-isomer specific 2-hydroxyacid dehydrogenase catalytic region-containing protein K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 470.0
HKD2_k127_7925301_1 ftsk spoiiie - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 358.0
HKD2_k127_7925301_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 337.0
HKD2_k127_7925301_3 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008588 273.0
HKD2_k127_7925301_4 - - - - 0.000000000000000000000000000000000000000002116 164.0
HKD2_k127_7925301_5 Transcriptional regulator, AbrB family K06284 - - 0.000000000000000000000000000000000000179 142.0
HKD2_k127_7925301_6 cluster protein-associated redox disulfide domain - - - 0.0000000000000000533 83.0
HKD2_k127_7925301_7 Methyltransferase K15460 - 2.1.1.223 0.000000000001046 68.0
HKD2_k127_7926265_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 512.0
HKD2_k127_7926265_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 440.0
HKD2_k127_7926265_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 376.0
HKD2_k127_7926265_3 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR K06383 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002986 248.0
HKD2_k127_7946944_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 346.0
HKD2_k127_7946944_1 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 305.0
HKD2_k127_7946944_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000002816 251.0
HKD2_k127_7946944_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000007116 240.0
HKD2_k127_7946944_4 Belongs to the UPF0296 family K09777 - - 0.000000000000000000000000000000000000000000413 159.0
HKD2_k127_7946944_5 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000001362 88.0
HKD2_k127_7977457_0 Belongs to the peptidase S16 family - - - 2.178e-248 790.0
HKD2_k127_7977457_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 4.122e-206 654.0
HKD2_k127_7977457_10 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K01227 - 3.2.1.96 0.000000000000000000003404 108.0
HKD2_k127_7977457_2 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 420.0
HKD2_k127_7977457_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 411.0
HKD2_k127_7977457_4 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 307.0
HKD2_k127_7977457_5 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 306.0
HKD2_k127_7977457_6 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000117 247.0
HKD2_k127_7977457_7 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.000000000000000000000000000000000000000000000000000002461 199.0
HKD2_k127_7977457_8 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000000001616 175.0
HKD2_k127_7977457_9 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000009652 166.0
HKD2_k127_7977492_0 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 477.0
HKD2_k127_7977492_1 CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 439.0
HKD2_k127_7977492_10 Recombinase - - - 0.00007884 45.0
HKD2_k127_7977492_11 Psort location Extracellular, score 8.82 - - - 0.000369 46.0
HKD2_k127_7977492_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07777 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 377.0
HKD2_k127_7977492_3 flavin reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000251 283.0
HKD2_k127_7977492_4 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000316 276.0
HKD2_k127_7977492_5 fOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001261 281.0
HKD2_k127_7977492_6 cyclohydrolase - - - 0.000000000000000000000000000000000000000000000000000000005378 205.0
HKD2_k127_7977492_7 Chemotaxis protein cheW K03408 - - 0.00000000000000000000000000000000000000000000001654 175.0
HKD2_k127_7977492_8 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000002854 161.0
HKD2_k127_7977492_9 UPF0291 protein - - - 0.00000000001049 68.0
HKD2_k127_7986201_0 Protein of unknown function, DUF255 K06888 - - 2.332e-275 861.0
HKD2_k127_7986201_1 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000004056 184.0
HKD2_k127_7986201_2 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000001069 171.0
HKD2_k127_7986201_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000002463 137.0
HKD2_k127_8015822_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 351.0
HKD2_k127_8015822_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000007147 207.0
HKD2_k127_8015822_2 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000005605 154.0
HKD2_k127_8015822_3 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000001134 130.0
HKD2_k127_8015822_4 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000001134 130.0
HKD2_k127_8015822_5 UBA TS-N domain - - - 0.0000000000000004317 79.0
HKD2_k127_8033142_0 helix_turn _helix lactose operon repressor K02529,K03604 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 474.0
HKD2_k127_8033142_1 PFAM Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 451.0
HKD2_k127_8033142_2 PFAM Binding-protein-dependent transport system inner membrane component K02026,K10242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 432.0
HKD2_k127_8033142_3 solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 428.0
HKD2_k127_8033142_4 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000000000000000000000000004875 142.0
HKD2_k127_8036885_0 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 369.0
HKD2_k127_8036885_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 319.0
HKD2_k127_8036885_2 Amidohydrolase family - - - 0.0000000000002072 74.0
HKD2_k127_8044170_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1105.0
HKD2_k127_8044170_1 ABC transporter K06158 - - 3.624e-288 890.0
HKD2_k127_8044170_10 Nucleotide-diphospho-sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007175 255.0
HKD2_k127_8044170_11 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001194 256.0
HKD2_k127_8044170_12 glycosyl transferase family 8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007242 250.0
HKD2_k127_8044170_13 Nucleotide-diphospho-sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008282 246.0
HKD2_k127_8044170_14 Fe-S iron-sulfur cluster assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000000000000000000004226 204.0
HKD2_k127_8044170_15 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000005654 199.0
HKD2_k127_8044170_16 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000003518 188.0
HKD2_k127_8044170_17 COG0515 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000001761 163.0
HKD2_k127_8044170_18 COG0515 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000103 151.0
HKD2_k127_8044170_19 Rubrerythrin - - - 0.0000000000002328 72.0
HKD2_k127_8044170_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 3.942e-203 644.0
HKD2_k127_8044170_20 Nucleotide-diphospho-sugar transferase - - - 0.000000000005028 68.0
HKD2_k127_8044170_21 PFAM PRC-barrel domain - - - 0.00000000001595 72.0
HKD2_k127_8044170_22 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.000001985 59.0
HKD2_k127_8044170_23 amine dehydrogenase activity - - - 0.000005759 57.0
HKD2_k127_8044170_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 578.0
HKD2_k127_8044170_4 AAA ATPase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 568.0
HKD2_k127_8044170_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 514.0
HKD2_k127_8044170_6 dehydratase K01709,K01710 - 4.2.1.45,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 506.0
HKD2_k127_8044170_7 Nucleotidyl transferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 338.0
HKD2_k127_8044170_8 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002207 274.0
HKD2_k127_8044170_9 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001418 267.0
HKD2_k127_8056032_0 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.0 1310.0
HKD2_k127_8056032_1 ATP-dependent helicase deoxyribonuclease subunit B K16899 - 3.6.4.12 0.0 1223.0
HKD2_k127_8056032_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 400.0
HKD2_k127_8056032_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03093 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005086 247.0
HKD2_k127_8056032_4 ATPase involved in DNA repair K03546 - - 0.000000000000000000000000000000000000000000000000000000000000658 220.0
HKD2_k127_8056032_5 Anti-sigma factor N-terminus - - - 0.000000000000000000000000000000001908 142.0
HKD2_k127_8056032_6 Tocopherol cyclase - - - 0.0000000000000000008093 90.0
HKD2_k127_8070377_0 PFAM Uncharacterised protein family (UPF0182) K09118 - - 1.104e-262 840.0
HKD2_k127_8070377_1 ABC transporter transmembrane region K18890 - - 8.681e-252 794.0
HKD2_k127_8070377_2 ABC transporter transmembrane region K18889 - - 4.921e-196 628.0
HKD2_k127_8070377_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000002312 212.0
HKD2_k127_8070377_4 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000013 188.0
HKD2_k127_8070377_5 Diguanylate cyclase - - - 0.0000000000000001436 82.0
HKD2_k127_8082641_0 PFAM Alcohol dehydrogenase K19956 - - 2.203e-202 636.0
HKD2_k127_8082641_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 569.0
HKD2_k127_8082641_2 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 542.0
HKD2_k127_8082641_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 304.0
HKD2_k127_8082641_4 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K00882 - 2.7.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 295.0
HKD2_k127_8082641_5 SEC-C motif - - - 0.00000000000000000000000000000000000000000000000000000000001663 211.0
HKD2_k127_8082641_6 PTS system mannitol-specific K02798,K02799,K02800 - 2.7.1.197 0.0000000000000000000000000000000000000000000000000004026 188.0
HKD2_k127_8082641_7 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000003706 178.0
HKD2_k127_8082641_8 - - - - 0.0000000000000000000000009379 105.0
HKD2_k127_8082641_9 phosphocarrier, HPr family K11189 - - 0.00000000000000000001843 93.0
HKD2_k127_8093069_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 356.0
HKD2_k127_8093069_1 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000000000000000000005991 224.0
HKD2_k127_8093069_2 - - - - 0.000000000000000000000000000000000007626 144.0
HKD2_k127_8093069_3 Family of unknown function (DUF5317) - - - 0.000001328 51.0
HKD2_k127_8116664_0 Na H antiporter K03315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 434.0
HKD2_k127_8116664_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 413.0
HKD2_k127_8116664_10 - - - - 0.00000000000000000000000000002017 129.0
HKD2_k127_8116664_11 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000006755 121.0
HKD2_k127_8116664_12 - - - - 0.00000000000000001122 92.0
HKD2_k127_8116664_13 Protein of unknown function (DUF3298) - - - 0.00000000000000003874 95.0
HKD2_k127_8116664_14 Belongs to the ompA family K03286 - - 0.000000002478 65.0
HKD2_k127_8116664_2 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 379.0
HKD2_k127_8116664_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 350.0
HKD2_k127_8116664_4 Streptomycin adenylyltransferase K05593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 335.0
HKD2_k127_8116664_5 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001466 253.0
HKD2_k127_8116664_6 hmm pf02080 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008654 250.0
HKD2_k127_8116664_7 WG containing repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000361 255.0
HKD2_k127_8116664_8 Belongs to the UPF0761 family K07058 - - 0.0000000000000000000000000000000000000000003839 168.0
HKD2_k127_8116664_9 Mor transcription activator family - - - 0.000000000000000000000000000000002786 130.0
HKD2_k127_8117223_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1259.0
HKD2_k127_8117223_1 PFAM extracellular solute-binding protein, family 5 K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 295.0
HKD2_k127_8117223_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000003019 265.0
HKD2_k127_8117223_3 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002035 260.0
HKD2_k127_8117223_4 Ubiquitin-associated translation elongation factor EF1B, N-terminal - - - 0.00000000000000000000000000000001361 133.0
HKD2_k127_8133557_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 4.215e-200 631.0
HKD2_k127_8133557_1 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 483.0
HKD2_k127_8133557_2 protein conserved in bacteria K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 299.0
HKD2_k127_8133557_3 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 289.0
HKD2_k127_8133557_4 Stage V sporulation protein S K06416 - - 0.0000000000000000000000000000000000000002443 150.0
HKD2_k127_8146522_0 Serine dehydratase alpha chain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 488.0
HKD2_k127_8146522_1 Na H antiporter K03315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009969 434.0
HKD2_k127_8146522_2 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 327.0
HKD2_k127_8146522_3 Domain of unknown function (DUF2383) K03594 - 1.16.3.1 0.00000000000000000000000006825 111.0
HKD2_k127_8146522_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000006944 106.0
HKD2_k127_8147518_0 TIGRFAM arsenical-resistance protein K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 566.0
HKD2_k127_8147518_1 Psort location CytoplasmicMembrane, score K07149 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 297.0
HKD2_k127_8147518_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004442 284.0
HKD2_k127_8147518_3 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000169 261.0
HKD2_k127_8147518_4 regulatory protein, arsR K03892 - - 0.000000000000000000000000000000000000000000000000000000005225 200.0
HKD2_k127_8147518_6 PFAM thioesterase superfamily protein K02614 - - 0.00000007674 53.0
HKD2_k127_8175450_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 5.4e-323 994.0
HKD2_k127_8175450_1 ABC-type nitrate sulfonate bicarbonate transport system, periplasmic component K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 286.0
HKD2_k127_8175450_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000004216 164.0
HKD2_k127_8181042_0 SpoVT / AbrB like domain K04769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002112 265.0
HKD2_k127_8181042_1 Alkaline phosphatase K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000003337 231.0
HKD2_k127_8181042_2 SurA N-terminal domain K03769,K07533 - 5.2.1.8 0.0000000000000000000000000000000000000000000000004666 187.0
HKD2_k127_8201986_0 Band 7 protein K07192 - - 2.405e-206 651.0
HKD2_k127_8201986_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 443.0
HKD2_k127_8201986_10 Small acid-soluble spore - - - 0.00000000000000000569 85.0
HKD2_k127_8201986_2 Acetyltransferase GNAT family K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 281.0
HKD2_k127_8201986_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004044 280.0
HKD2_k127_8201986_4 PFAM Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001642 256.0
HKD2_k127_8201986_5 Domain of unknown function (DUF1836) - - - 0.000000000000000000000000000000000000000000000000000000000000000006929 231.0
HKD2_k127_8201986_6 Membrane protein implicated in regulation of membrane protease activity - - - 0.000000000000000000000000000000000000000001164 166.0
HKD2_k127_8201986_7 Chemotaxis protein CheY K03413 - - 0.000000000000000000000000000000116 129.0
HKD2_k127_8201986_8 EamA-like transporter family - - - 0.00000000000000000000000000004873 119.0
HKD2_k127_8201986_9 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000000000000000000009378 100.0
HKD2_k127_8207495_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 1.209e-267 830.0
HKD2_k127_8207495_1 Haloacid dehalogenase-like hydrolase - - - 1.879e-226 710.0
HKD2_k127_8207495_10 ADP-heptose synthase, bifunctional sugar kinase adenylyltransferase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 465.0
HKD2_k127_8207495_11 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 442.0
HKD2_k127_8207495_12 NmrA-like family K01784,K02473,K03274 - 5.1.3.2,5.1.3.20,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 434.0
HKD2_k127_8207495_13 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 413.0
HKD2_k127_8207495_14 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 362.0
HKD2_k127_8207495_15 transport system permease K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 306.0
HKD2_k127_8207495_16 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000497 260.0
HKD2_k127_8207495_17 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001279 239.0
HKD2_k127_8207495_18 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007989 243.0
HKD2_k127_8207495_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000003595 233.0
HKD2_k127_8207495_2 Mate efflux family protein - - - 3.471e-223 700.0
HKD2_k127_8207495_20 LICD family K07271 - - 0.000000000000000000000000000000000007071 146.0
HKD2_k127_8207495_3 protein TIM barrel - - - 2.689e-200 625.0
HKD2_k127_8207495_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 612.0
HKD2_k127_8207495_5 Glycerol-3-phosphate cytidylyltransferase K00980 - 2.7.7.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 597.0
HKD2_k127_8207495_6 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 587.0
HKD2_k127_8207495_7 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 584.0
HKD2_k127_8207495_8 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 535.0
HKD2_k127_8207495_9 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 469.0
HKD2_k127_8211355_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.626e-259 806.0
HKD2_k127_8211355_1 Protein of unknown function (DUF554) K07150 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007177 254.0
HKD2_k127_8211355_2 8-oxoguanine DNA glycosylase, N-terminal domain K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000001057 168.0
HKD2_k127_8211355_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000002912 156.0
HKD2_k127_8246437_0 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 402.0
HKD2_k127_8246437_1 Spore maturation protein K06373 - - 0.000000000000000000000000000000000000000000000000000000000128 209.0
HKD2_k127_8246437_2 acetyltransferase - - - 0.00000000000000000002275 99.0
HKD2_k127_8246437_3 Spore maturation protein K06374 - - 0.00000000000000001173 88.0
HKD2_k127_8280132_0 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 411.0
HKD2_k127_8280132_1 Zinc dependent phospholipase C - - - 0.00000000000000000001803 97.0
HKD2_k127_8280132_2 - - - - 0.000001164 51.0
HKD2_k127_8283915_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 563.0
HKD2_k127_8283915_1 Protein of unknown function (DUF3298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 381.0
HKD2_k127_8283915_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000404 223.0
HKD2_k127_8293158_0 hmm pf00665 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 436.0
HKD2_k127_8293158_1 hmm pf01527 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005444 278.0
HKD2_k127_8293158_2 Sigma-70, region 4 - - - 0.0000000000000002626 79.0
HKD2_k127_8314993_0 Belongs to the BCCT transporter (TC 2.A.15) family K02168,K05020 - - 5.546e-224 699.0
HKD2_k127_8314993_1 Bacterial regulatory protein, Fis family K06714 - - 1.083e-220 696.0
HKD2_k127_8314993_2 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000000000000001225 162.0
HKD2_k127_8314993_3 membrane - - - 0.000000000000000000000000000000000000001582 163.0
HKD2_k127_8314993_4 SNARE associated Golgi protein - - - 0.000000000000000000001521 97.0
HKD2_k127_8335966_0 ABC transporter, transmembrane region K06147 - - 0.0 1049.0
HKD2_k127_8335966_1 ABC-type multidrug transport system ATPase and permease K06147 - - 2.72e-303 941.0
HKD2_k127_8335966_2 - - - - 0.000000000000000000000000000000000000000000011 168.0
HKD2_k127_8335966_3 PFAM regulatory protein, MarR - - - 0.0000000000000000000000000000000000000000004293 160.0
HKD2_k127_8481653_0 chemotaxis K03406 - - 1.587e-260 818.0
HKD2_k127_8481653_1 Putative diguanylate phosphodiesterase - - - 9.481e-246 790.0
HKD2_k127_8481653_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 578.0
HKD2_k127_8481653_3 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 421.0
HKD2_k127_8481653_4 Response regulator containing CheY-like receiver and SARP domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 404.0
HKD2_k127_8481653_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004141 295.0
HKD2_k127_8481653_6 Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004098 256.0
HKD2_k127_8481653_7 Diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000000000000005919 237.0
HKD2_k127_8481653_8 Response regulator receiver domain - - - 0.000000000000000000000000000000003081 147.0
HKD2_k127_8579801_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 531.0
HKD2_k127_8579801_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 501.0
HKD2_k127_8579801_2 Psort location Cytoplasmic, score 8.87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001055 255.0
HKD2_k127_872525_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.318e-274 862.0
HKD2_k127_872525_1 biosynthesis protein K15894 - 4.2.1.115 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 575.0
HKD2_k127_872525_10 pseudaminic acid biosynthesis-associated protein PseG K15897 - 3.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 318.0
HKD2_k127_872525_11 Belongs to the bacterial flagellin family K02397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 304.0
HKD2_k127_872525_12 Cytidylyltransferase K07257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001444 274.0
HKD2_k127_872525_13 Psort location Cytoplasmic, score K18475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004601 282.0
HKD2_k127_872525_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000001984 200.0
HKD2_k127_872525_15 PFAM Phosphoribosyltransferase K02242 - - 0.0000000000000000000000000000000000000000002334 167.0
HKD2_k127_872525_16 flagellar protein FliS K02422 - - 0.00000000000000000000000000000000000000003847 158.0
HKD2_k127_872525_17 - - - - 0.00000000000000000000000000000000000000003847 158.0
HKD2_k127_872525_18 TIGRFAM flagellar operon protein - - - 0.000000000000000000000000000000000000001045 151.0
HKD2_k127_872525_19 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000009139 142.0
HKD2_k127_872525_2 synthase K01654,K15898 - 2.5.1.56,2.5.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 570.0
HKD2_k127_872525_20 FlaG protein K06603 - - 0.0000000000000000000000000000002556 126.0
HKD2_k127_872525_21 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.000000000000000000000000000001864 125.0
HKD2_k127_872525_22 PFAM FlgN - - - 0.00000000000000000000001813 106.0
HKD2_k127_872525_23 - - - - 0.00000000000000000001723 96.0
HKD2_k127_872525_25 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000000007097 73.0
HKD2_k127_872525_26 Anti-sigma-28 factor, FlgM K02398 - - 0.00000004992 58.0
HKD2_k127_872525_3 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009373 563.0
HKD2_k127_872525_4 Protein of unknown function DUF115 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 461.0
HKD2_k127_872525_5 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 447.0
HKD2_k127_872525_6 flagellar hook-associated protein K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 405.0
HKD2_k127_872525_7 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 378.0
HKD2_k127_872525_8 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 381.0
HKD2_k127_872525_9 flagellar hook-associated protein K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 342.0
HKD2_k127_878661_0 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 1.082e-238 746.0
HKD2_k127_878661_1 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 1.391e-196 627.0
HKD2_k127_878661_2 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000002185 154.0
HKD2_k127_878661_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000009087 129.0
HKD2_k127_878661_4 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000009037 107.0
HKD2_k127_8889434_0 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000004218 251.0
HKD2_k127_8889434_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000001396 234.0
HKD2_k127_8905569_0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 1.306e-261 812.0
HKD2_k127_8905569_1 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 407.0
HKD2_k127_8905569_2 ATPase domain of DNA mismatch repair MUTS family K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001083 287.0
HKD2_k127_8905569_3 PKD domain containing protein - - - 0.00007262 55.0
HKD2_k127_8952581_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.368e-204 640.0
HKD2_k127_8952581_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001364 278.0
HKD2_k127_8952581_2 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001291 253.0
HKD2_k127_8952581_3 Protein of unknown function (DUF1294) - - - 0.00000000000000000000000001242 111.0
HKD2_k127_8952581_4 Preprotein translocase SecG subunit K03075 - - 0.00000000000001017 76.0
HKD2_k127_895466_0 Pilus assembly protein K02283 - - 0.00000000000000000000000002396 125.0
HKD2_k127_895466_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000003133 88.0
HKD2_k127_895466_2 S-layer homology domain - - - 0.0000000000005538 75.0
HKD2_k127_895466_3 - - - - 0.000000000002138 76.0
HKD2_k127_895466_4 Transposase IS200 like - - - 0.000000001357 64.0
HKD2_k127_895466_5 Involved in chromosome partitioning - - - 0.0000004473 61.0
HKD2_k127_895466_6 CobQ CobB MinD ParA nucleotide binding domain - - - 0.00004012 55.0
HKD2_k127_8963615_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 6.129e-268 833.0
HKD2_k127_8963615_1 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 4.602e-252 785.0
HKD2_k127_8963615_2 Belongs to the mannitol dehydrogenase family. UxaB subfamily K00041 - 1.1.1.58 3.402e-239 746.0
HKD2_k127_8963615_3 Psort location CytoplasmicMembrane, score 10.00 K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 431.0
HKD2_k127_8963615_4 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 414.0
HKD2_k127_8963615_5 transcriptional regulator (RpiR family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 405.0
HKD2_k127_8963615_6 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000001548 202.0
HKD2_k127_8963615_7 D-galactarate dehydratase altronate hydrolase K01685 - 4.2.1.7 0.0000000000000000001528 90.0
HKD2_k127_8964181_0 Radical SAM domain protein - - - 7.935e-272 848.0
HKD2_k127_8964181_1 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 510.0
HKD2_k127_8964181_10 Cell shape determining protein, MreB Mrl family K03569 - - 0.00004098 46.0
HKD2_k127_8964181_2 Belongs to the ParA family K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 423.0
HKD2_k127_8964181_3 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000002977 201.0
HKD2_k127_8964181_4 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.000000000000000000000000000000000000000000000001776 181.0
HKD2_k127_8964181_5 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000000000000000000000005057 136.0
HKD2_k127_8964181_6 Peptidase family M23 - - - 0.000000000000000000000000000000000102 143.0
HKD2_k127_8964181_7 Radical SAM-linked protein - - - 0.0000000000000000000000000000001401 128.0
HKD2_k127_8964181_8 PFAM Peptidase family M50 K06402 - - 0.0000000000000000000000000000002312 134.0
HKD2_k127_8964181_9 rod shape-determining protein MreD K03571 - - 0.000000000000000000001599 100.0
HKD2_k127_8964401_0 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 620.0
HKD2_k127_8964401_1 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 378.0
HKD2_k127_8965985_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 385.0
HKD2_k127_8965985_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000009608 191.0
HKD2_k127_8965985_2 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000005328 192.0
HKD2_k127_8965985_3 Protein of unknown function (DUF3221) - - - 0.00000000000000000000000000000000124 136.0
HKD2_k127_8965985_4 - - - - 0.000000000000000000791 89.0
HKD2_k127_8983930_0 PFAM ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 613.0
HKD2_k127_8983930_1 Protein of unknown function (DUF3798) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 569.0
HKD2_k127_8983930_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 551.0
HKD2_k127_8983930_3 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 320.0
HKD2_k127_8983930_4 response regulator K11692 - - 0.00000000000000000000000000000000000000000000000000000000000000006689 229.0
HKD2_k127_8983930_5 GHKL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003537 238.0
HKD2_k127_8983930_6 - - - - 0.0000000000000000000000002551 113.0
HKD2_k127_8996503_0 modulator of DNA gyrase K03568 - - 1.115e-201 637.0
HKD2_k127_8996503_1 Histidine kinase-like ATPases K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 468.0
HKD2_k127_8996503_2 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 456.0
HKD2_k127_8996503_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 346.0
HKD2_k127_8996503_4 proline dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 323.0
HKD2_k127_8996503_5 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000002029 232.0
HKD2_k127_8996503_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000003014 235.0
HKD2_k127_9037997_0 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.0 1232.0
HKD2_k127_9037997_1 EamA-like transporter family K15268 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 432.0
HKD2_k127_9037997_2 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004298 263.0
HKD2_k127_9037997_3 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000002775 149.0
HKD2_k127_9037997_4 PFAM thioesterase superfamily - - - 0.00000000000000000001393 93.0
HKD2_k127_9037997_5 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000008707 82.0
HKD2_k127_9068158_0 Sterol carrier protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 393.0
HKD2_k127_9068158_1 GHKL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 325.0
HKD2_k127_9068158_2 transcriptional regulator, ArsR family - - - 0.00000000000000000000000000000000000000000000000000002341 201.0
HKD2_k127_9068158_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000002524 173.0
HKD2_k127_9068158_4 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000002502 183.0
HKD2_k127_9069627_0 glutamine synthetase K01915 - 6.3.1.2 6.059e-247 779.0
HKD2_k127_9069627_1 Cystathionine beta-lyase family protein involved in aluminum resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 571.0
HKD2_k127_9069627_10 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.00000000000000000002873 95.0
HKD2_k127_9069627_11 - - - - 0.0000000000004171 72.0
HKD2_k127_9069627_12 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000009167 59.0
HKD2_k127_9069627_13 Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery - GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.000001232 54.0
HKD2_k127_9069627_14 Endoribonuclease L-PSP - - - 0.00003359 47.0
HKD2_k127_9069627_2 His Kinase A (phosphoacceptor) domain K07651,K07652 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 499.0
HKD2_k127_9069627_3 Belongs to the 'phage' integrase family K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 427.0
HKD2_k127_9069627_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 374.0
HKD2_k127_9069627_5 PFAM response regulator receiver K07775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009798 326.0
HKD2_k127_9069627_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 290.0
HKD2_k127_9069627_7 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000002835 234.0
HKD2_k127_9069627_8 - - - - 0.00000000000000000000000000000000000000000000001904 175.0
HKD2_k127_9069627_9 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000008355 133.0
HKD2_k127_9080101_0 PFAM ATPase associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 459.0
HKD2_k127_9080101_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 318.0
HKD2_k127_9080101_2 Domain of unknown function (DUF1904) - - - 0.00000000000000000000000000002467 120.0
HKD2_k127_9088274_0 TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 550.0
HKD2_k127_9088274_1 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000002117 221.0
HKD2_k127_9088274_2 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000001389 125.0
HKD2_k127_9088274_3 Winged helix DNA-binding domain K22296 - - 0.000000000000000000000000001933 117.0
HKD2_k127_9100690_0 spore germination protein K06295 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001619 243.0
HKD2_k127_9100690_1 Spore germination B3/ GerAC like, C-terminal K06297 - - 0.0000000000000000000000000000000000000000000000000000000000000000004683 243.0
HKD2_k127_9100690_2 TIGRFAM spore germination protein K06296 - - 0.000000000507 70.0
HKD2_k127_9100868_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 413.0
HKD2_k127_9100868_1 Carboxypeptidase K01308 - 3.4.19.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002264 272.0
HKD2_k127_9100868_2 GntR family - - - 0.000000000000000000000000000000000000000000000000000158 187.0
HKD2_k127_9100868_3 - - - - 0.0000000000000000000000000000000000001038 151.0
HKD2_k127_9100868_4 PFAM Rubrerythrin - - - 0.000000000000000000000406 95.0
HKD2_k127_9108980_0 Superfamily I DNA and RNA K03657 - 3.6.4.12 1.609e-288 904.0
HKD2_k127_9108980_1 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000148 280.0
HKD2_k127_9108980_2 Acetyltransferase (GNAT) domain - - - 0.000000000001867 73.0
HKD2_k127_9117219_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03169 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 536.0
HKD2_k127_9117219_1 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide K01479 - 3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 511.0
HKD2_k127_9117219_2 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 421.0
HKD2_k127_9117219_3 Uncharacterised protein family (UPF0160) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 369.0
HKD2_k127_9117219_4 pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000001204 125.0
HKD2_k127_9133308_0 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 316.0
HKD2_k127_9133308_1 cell envelope-related function transcriptional attenuator - - - 0.0000000000000000000000000000000000000000000000006801 187.0
HKD2_k127_9133308_2 Protein of unknown function (DUF3343) - - - 0.00000000000002202 76.0
HKD2_k127_9135385_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.863e-194 616.0
HKD2_k127_9135385_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 320.0
HKD2_k127_9135385_2 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
HKD2_k127_9135385_3 - - - - 0.00000000009194 71.0
HKD2_k127_9156066_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 1.451e-209 662.0
HKD2_k127_9156066_1 tail specific protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 479.0
HKD2_k127_9156066_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000005864 70.0
HKD2_k127_9156066_3 DNA protecting protein DprA K04096 - - 0.00000001162 60.0
HKD2_k127_9162882_0 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 2.018e-260 810.0
HKD2_k127_9162882_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 442.0
HKD2_k127_9162882_2 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 415.0
HKD2_k127_9162882_3 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 357.0
HKD2_k127_9162882_4 Fibronectin-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 299.0
HKD2_k127_9162882_5 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003788 245.0
HKD2_k127_9162882_6 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000357 229.0
HKD2_k127_9162882_7 - - - - 0.00000000000000000000000000000000000000000002511 169.0
HKD2_k127_9162882_8 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000007536 74.0
HKD2_k127_9166119_0 PFAM Ketopantoate reductase K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 573.0
HKD2_k127_9166119_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K14415 - 2.7.9.2,6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 594.0
HKD2_k127_9166119_10 S-layer domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004035 312.0
HKD2_k127_9166119_11 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000002371 251.0
HKD2_k127_9166119_12 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000005726 221.0
HKD2_k127_9166119_13 -acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000008967 213.0
HKD2_k127_9166119_14 - - - - 0.000000000000000000000000346 110.0
HKD2_k127_9166119_16 Bacterial Ig-like domain 2 - - - 0.00000000000000000002021 109.0
HKD2_k127_9166119_17 domain, Protein - - - 0.00000000000000001482 99.0
HKD2_k127_9166119_2 2-hydroxyglutaryl-CoA dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 557.0
HKD2_k127_9166119_3 CoA-substrate-specific enzyme activase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 441.0
HKD2_k127_9166119_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 428.0
HKD2_k127_9166119_5 Major facilitator superfamily K08217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 404.0
HKD2_k127_9166119_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 378.0
HKD2_k127_9166119_7 Transcriptional regulator C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 348.0
HKD2_k127_9166119_8 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 347.0
HKD2_k127_9166119_9 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 312.0
HKD2_k127_9195_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 305.0
HKD2_k127_9195_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000001255 229.0
HKD2_k127_9195_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000003575 212.0
HKD2_k127_9195471_0 Psort location Cytoplasmic, score K00821,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 5.461e-227 709.0
HKD2_k127_9195471_1 S-layer homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008955 263.0
HKD2_k127_9195471_2 ATP-grasp domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000008569 193.0
HKD2_k127_9215435_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 473.0
HKD2_k127_9215435_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 320.0
HKD2_k127_9215435_2 binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 298.0
HKD2_k127_9215435_3 response to abiotic stimulus - - - 0.00000000000000000001206 101.0
HKD2_k127_9215435_4 YCII-related domain K09780 - - 0.00000000005285 63.0
HKD2_k127_9272833_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 342.0
HKD2_k127_9272833_1 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000000000000000000000000000000000000000001829 210.0
HKD2_k127_9272833_2 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system K02071 - - 0.000000000000000000000000000000003518 130.0
HKD2_k127_9272833_3 - - - - 0.0000005483 56.0
HKD2_k127_9275793_0 ABC transporter C-terminal domain K15738 - - 2.637e-287 893.0
HKD2_k127_9275793_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.461e-264 823.0
HKD2_k127_9275793_10 - - - - 0.00000000000000000000000000000000669 133.0
HKD2_k127_9275793_11 - - - - 0.0000001318 55.0
HKD2_k127_9275793_2 MATE efflux family protein - - - 6.836e-202 638.0
HKD2_k127_9275793_3 Mate efflux family protein - - - 5.818e-198 625.0
HKD2_k127_9275793_4 Phosphotransferase system, EIIC K07035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 498.0
HKD2_k127_9275793_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 323.0
HKD2_k127_9275793_6 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 316.0
HKD2_k127_9275793_7 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 298.0
HKD2_k127_9275793_8 Protein of unknown function (DUF434) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000101 284.0
HKD2_k127_9275793_9 - - - - 0.000000000000000000000000000000000000000000001264 169.0
HKD2_k127_9281696_0 FtsX-like permease family K02004 - - 0.0 1019.0
HKD2_k127_9281696_1 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes K05592 - 3.6.4.13 3.882e-248 772.0
HKD2_k127_9281696_10 Platelet-activating factor acetylhydrolase, isoform II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001094 271.0
HKD2_k127_9281696_11 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001393 261.0
HKD2_k127_9281696_12 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000242 254.0
HKD2_k127_9281696_13 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000004533 230.0
HKD2_k127_9281696_14 Transcriptional regulator - - - 0.000000000000000000000000000000000000004262 149.0
HKD2_k127_9281696_15 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.0000000000000000000000000189 111.0
HKD2_k127_9281696_16 Uncharacterized conserved protein (DUF2196) - - - 0.0000000007188 60.0
HKD2_k127_9281696_2 Histidine kinase K07646 - 2.7.13.3 3.293e-211 666.0
HKD2_k127_9281696_3 potassium uptake protein, TrkH family K03498 - - 2.644e-208 655.0
HKD2_k127_9281696_4 ABC-type multidrug transport system ATPase component K01990,K19309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 433.0
HKD2_k127_9281696_5 transcriptional regulatory protein K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 400.0
HKD2_k127_9281696_6 Potassium uptake protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 374.0
HKD2_k127_9281696_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 371.0
HKD2_k127_9281696_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 312.0
HKD2_k127_9281696_9 tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 312.0
HKD2_k127_9284456_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 604.0
HKD2_k127_9284456_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 502.0
HKD2_k127_9284456_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 451.0
HKD2_k127_9284456_3 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 429.0
HKD2_k127_9284456_4 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 344.0
HKD2_k127_9284456_5 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 340.0
HKD2_k127_9284456_6 - - - - 0.000000000000000001104 93.0
HKD2_k127_9330361_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 584.0
HKD2_k127_9330361_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 353.0
HKD2_k127_9330361_2 mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000001552 193.0
HKD2_k127_9330361_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000001858 161.0
HKD2_k127_9330361_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000003822 154.0
HKD2_k127_9330361_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000001626 101.0
HKD2_k127_9330361_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000001459 62.0
HKD2_k127_9330361_7 ATP synthase B/B' CF(0) K02109 - - 0.0000005342 57.0
HKD2_k127_9330361_8 Transcriptional regulatory protein, C terminal K07658 - - 0.0005392 52.0
HKD2_k127_9351635_0 transcriptional regulatory protein K02475,K11615,K11692,K11712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001197 265.0
HKD2_k127_9351635_1 FAD dependent oxidoreductase K00239,K00244 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000001247 160.0
HKD2_k127_9351635_2 signal transduction histidine kinase regulating citrate malate metabolism K11614,K11691 - 2.7.13.3 0.000000000000000000000000000000000004461 141.0
HKD2_k127_9372622_0 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 499.0
HKD2_k127_9372622_1 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22341 - 1.17.1.11,1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000005227 214.0
HKD2_k127_9372622_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000001839 83.0
HKD2_k127_9413508_0 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 392.0
HKD2_k127_9413508_2 FMN binding - - - 0.000000000000000000000000000000000000000000000000000009968 193.0
HKD2_k127_9413508_3 transcriptional regulator - - - 0.0000000000000000000000000000001183 131.0
HKD2_k127_9413508_4 PFAM FMN-binding domain - - - 0.0000000000000000000000000001274 119.0
HKD2_k127_9424200_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 1.293e-232 724.0
HKD2_k127_9424200_1 Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 433.0
HKD2_k127_9424200_2 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 421.0
HKD2_k127_9424200_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000000000000002532 217.0
HKD2_k127_9425845_0 pyrimidine-nucleoside phosphorylase K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 612.0
HKD2_k127_9425845_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 551.0
HKD2_k127_9425845_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000002261 74.0
HKD2_k127_9425845_2 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 480.0
HKD2_k127_9425845_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 391.0
HKD2_k127_9425845_4 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 370.0
HKD2_k127_9425845_5 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 352.0
HKD2_k127_9425845_6 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 349.0
HKD2_k127_9425845_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000001873 208.0
HKD2_k127_9425845_8 peptidase - - - 0.00000000000000000000000000000000000000000000000000003893 194.0
HKD2_k127_9425845_9 stage ii sporulation protein m K06384 - - 0.000000000000003133 81.0
HKD2_k127_9459291_0 Endoribonuclease that initiates mRNA decay K18682 - - 3.573e-236 739.0
HKD2_k127_9459291_1 Belongs to the FtsK SpoIIIE SftA family K03466 - - 8.517e-214 686.0
HKD2_k127_9459291_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 535.0
HKD2_k127_9459291_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 522.0
HKD2_k127_9459291_4 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 450.0
HKD2_k127_9459291_5 protein conserved in bacteria K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 316.0
HKD2_k127_9459291_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 0.0000000000000000000000000000000000000000000000001402 182.0
HKD2_k127_9459291_7 Modulates RecA activity K03565 - - 0.00000000000000000000000008203 115.0
HKD2_k127_9459291_8 Stage V sporulation protein S K06416 - - 0.000000000000005421 75.0
HKD2_k127_9468439_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1186.0
HKD2_k127_9468439_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 1.862e-276 854.0
HKD2_k127_9468439_10 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000252 142.0
HKD2_k127_9468439_11 'small, acid-soluble spore protein K06421 - - 0.00000000000000000000003456 99.0
HKD2_k127_9468439_12 PFAM helix-turn-helix domain protein - - - 0.0000000000000000001199 98.0
HKD2_k127_9468439_13 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000006864 51.0
HKD2_k127_9468439_2 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 464.0
HKD2_k127_9468439_3 PFAM peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 368.0
HKD2_k127_9468439_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 339.0
HKD2_k127_9468439_5 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 315.0
HKD2_k127_9468439_6 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000005072 226.0
HKD2_k127_9468439_7 aspartate carbamoyltransferase, regulatory K00610 - - 0.000000000000000000000000000000000000000000000000000000003545 201.0
HKD2_k127_9468439_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000002732 190.0
HKD2_k127_9468439_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000002878 178.0
HKD2_k127_9504547_0 Domain of unknown function (DUF2935) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 460.0
HKD2_k127_9504547_1 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 375.0
HKD2_k127_9504547_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 300.0
HKD2_k127_9504547_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000001067 179.0
HKD2_k127_9504547_4 - - - - 0.000000000000000000000000000000000000000001391 163.0
HKD2_k127_9504547_5 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.0000000000000000000000000000000000003771 147.0
HKD2_k127_9504547_6 - - - - 0.00000000000000000000000000007991 118.0
HKD2_k127_9504547_7 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000005004 89.0
HKD2_k127_9504547_8 Protein of unknown function, DUF255 K06888 - - 0.00000000000001522 76.0
HKD2_k127_9504547_9 - - - - 0.0002582 46.0
HKD2_k127_9573969_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 507.0
HKD2_k127_9573969_1 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 429.0
HKD2_k127_9573969_2 Methyltransferase TRM13 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 394.0
HKD2_k127_9573969_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 353.0
HKD2_k127_9573969_4 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 341.0
HKD2_k127_9573969_5 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001127 288.0
HKD2_k127_9573969_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004421 224.0
HKD2_k127_9573969_7 ArsC family - - - 0.00000000000000000000000000000000000000000000001328 173.0
HKD2_k127_9573969_8 Cupin - - - 0.00000006486 58.0
HKD2_k127_9603625_0 Belongs to the carbamoyltransferase HypF family K04656 - - 4.061e-245 779.0
HKD2_k127_9603625_1 hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002392 280.0
HKD2_k127_9603625_2 hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000000000000000000001061 204.0
HKD2_k127_9603625_3 PFAM cytochrome - - - 0.000000000000000000000000000000005176 132.0
HKD2_k127_9603625_4 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000000004675 110.0
HKD2_k127_9738277_0 PFAM PilT protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 412.0
HKD2_k127_9738277_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 314.0
HKD2_k127_9738277_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000001371 240.0
HKD2_k127_9738277_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000003114 229.0
HKD2_k127_9738277_4 PFAM Transcription factor CarD K07736 - - 0.00000000000000000000000000000000000000000000000000002933 192.0
HKD2_k127_9757608_0 acetyl-CoA hydrolase - - - 9.007e-218 682.0
HKD2_k127_9757608_1 PFAM sigma-54 factor interaction domain-containing protein - - - 1.098e-197 626.0
HKD2_k127_9757608_10 Ndr family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 314.0
HKD2_k127_9757608_11 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 312.0
HKD2_k127_9757608_12 Domain of unknown function (DUF1887) - - - 0.0000000000000000000000000000000000000000000000482 182.0
HKD2_k127_9757608_13 - - - - 0.00000000000000000000000000000000001236 139.0
HKD2_k127_9757608_14 Helix-turn-helix domain K20342,K20391 - - 0.0000000000009935 80.0
HKD2_k127_9757608_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 540.0
HKD2_k127_9757608_3 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 529.0
HKD2_k127_9757608_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 492.0
HKD2_k127_9757608_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 451.0
HKD2_k127_9757608_6 Belongs to the binding-protein-dependent transport system permease family K01998,K11961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 401.0
HKD2_k127_9757608_7 Enoyl-(Acyl carrier protein) reductase K00059,K00076 - 1.1.1.100,1.1.1.159 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 366.0
HKD2_k127_9757608_8 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 366.0
HKD2_k127_9757608_9 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 332.0
HKD2_k127_9762657_0 PFAM AIR synthase related protein K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 380.0
HKD2_k127_9762657_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000009063 233.0
HKD2_k127_9762657_2 - - - - 0.00001148 53.0
HKD2_k127_9787808_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.534e-311 959.0
HKD2_k127_9787808_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000007807 159.0
HKD2_k127_9787808_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000001032 162.0
HKD2_k127_9829317_0 Histidine ammonia-lyase K01745 - 4.3.1.3 7.529e-222 697.0
HKD2_k127_9829317_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 589.0
HKD2_k127_9829317_2 Peptidase, M23 - - - 0.000000000000000000000000000000000000000000000000006476 192.0
HKD2_k127_9829317_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000001208 162.0
HKD2_k127_9829317_4 - - - - 0.0000000000000000000000000000000001592 134.0
HKD2_k127_9829317_5 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000001936 130.0
HKD2_k127_9829317_6 - - - - 0.00000000000000000003302 98.0
HKD2_k127_9829317_7 Belongs to the UPF0180 family - - - 0.00000000001579 68.0
HKD2_k127_9829317_8 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000007305 55.0
HKD2_k127_9870373_0 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 362.0
HKD2_k127_9870373_1 Transposase (IS116 IS110 IS902 family) K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 358.0
HKD2_k127_9870373_2 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 359.0
HKD2_k127_9870373_3 Protein of unknown function (DUF975) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 353.0
HKD2_k127_9870373_4 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000002668 208.0
HKD2_k127_9870373_5 Histidine kinase K07718 - 2.7.13.3 0.0000000000000000000000003871 105.0
HKD2_k127_9968299_0 Domain of unknown function (DUF4153) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 517.0
HKD2_k127_9968299_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000002546 217.0
HKD2_k127_9968299_2 - - - - 0.00000000000000000000000000000007986 135.0