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Overview

ID MAG01842
Name HKD3_bin.23
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Casimicrobiaceae
Genus VBCG01
Species
Assembly information
Completeness (%) 59.63
Contamination (%) 1.0
GC content (%) 70.0
N50 (bp) 18,759
Genome size (bp) 2,333,313

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2156

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_113601_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 282.0
HKD3_k127_113601_1 methyltransferase K03437 - - 0.0000000000000000000000000000000000000000000000000000000000009072 221.0
HKD3_k127_113601_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000002026 123.0
HKD3_k127_1211036_0 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 287.0
HKD3_k127_1211036_1 lytic transglycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000023 288.0
HKD3_k127_1211036_2 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000002352 219.0
HKD3_k127_1211036_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000003384 76.0
HKD3_k127_1242769_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.435e-219 692.0
HKD3_k127_1242769_1 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 315.0
HKD3_k127_1242769_2 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000002677 139.0
HKD3_k127_124533_0 DNA topoisomerase III K03169 - 5.99.1.2 0.0 1150.0
HKD3_k127_124533_1 FtsX-like permease family K02004 - - 2.007e-245 794.0
HKD3_k127_124533_10 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000003484 228.0
HKD3_k127_124533_11 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000004002 199.0
HKD3_k127_124533_12 Protein of unknown function (DUF2905) - - - 0.000000000000000000000001011 104.0
HKD3_k127_124533_13 acid phosphatase activity K01077 - 3.1.3.1 0.000000000000000000006408 94.0
HKD3_k127_124533_14 cyclic nucleotide binding K10914 - - 0.0000000000000000001638 98.0
HKD3_k127_124533_2 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 602.0
HKD3_k127_124533_3 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 426.0
HKD3_k127_124533_4 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 349.0
HKD3_k127_124533_5 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 351.0
HKD3_k127_124533_6 ABC transporter K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 311.0
HKD3_k127_124533_7 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000532 289.0
HKD3_k127_124533_8 PFAM Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001643 292.0
HKD3_k127_124533_9 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001396 271.0
HKD3_k127_1246350_0 Phospholipase, patatin family K07001 - - 3.195e-206 652.0
HKD3_k127_1246350_1 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009065 255.0
HKD3_k127_1246350_2 ABC transporter substrate-binding protein - - - 0.0002902 47.0
HKD3_k127_1254324_0 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846 - 4.4.1.24 7.825e-227 708.0
HKD3_k127_1254324_1 ABC-type nitrate sulfonate bicarbonate transport system, periplasmic component K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 463.0
HKD3_k127_1254324_2 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 422.0
HKD3_k127_1254324_3 abc transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 394.0
HKD3_k127_1254324_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 344.0
HKD3_k127_1254324_5 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.00000000000000000000000000000000000000000000000000000002601 205.0
HKD3_k127_1254324_6 Domain of unknown function (DUF4397) - - - 0.000000000000000000003447 107.0
HKD3_k127_1254324_7 - - - - 0.00000000000000000003176 94.0
HKD3_k127_127469_0 Sulfatase K01130 - 3.1.6.1 2.901e-251 789.0
HKD3_k127_127469_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 563.0
HKD3_k127_127469_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000002701 135.0
HKD3_k127_127469_11 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000002813 112.0
HKD3_k127_127469_12 Predicted integral membrane protein (DUF2282) - - - 0.000000000000000000000001174 110.0
HKD3_k127_127469_13 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0002096 46.0
HKD3_k127_127469_2 ABC transporter K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 387.0
HKD3_k127_127469_3 belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 355.0
HKD3_k127_127469_4 mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 337.0
HKD3_k127_127469_5 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 333.0
HKD3_k127_127469_6 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000000000000000000000000000000000000000002053 233.0
HKD3_k127_127469_7 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001241 220.0
HKD3_k127_127469_8 PFAM Cytochrome c, class I K08738 - - 0.0000000000000000000000000000000000000000000004326 169.0
HKD3_k127_127469_9 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000001317 175.0
HKD3_k127_1276613_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 2.563e-295 920.0
HKD3_k127_1276613_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005922 283.0
HKD3_k127_1276613_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000001691 136.0
HKD3_k127_1276613_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000004082 88.0
HKD3_k127_1278556_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 3.595e-211 667.0
HKD3_k127_1278556_1 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 509.0
HKD3_k127_1278556_10 VanZ like family - - - 0.00000000000000000000000000000000001441 149.0
HKD3_k127_1278556_11 Phospholipid methyltransferase - - - 0.0000000000004071 83.0
HKD3_k127_1278556_12 SCP-2 sterol transfer family K03690 - - 0.000000000004935 76.0
HKD3_k127_1278556_2 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 534.0
HKD3_k127_1278556_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007778 524.0
HKD3_k127_1278556_4 Binding-protein-dependent transport system inner membrane component K02054,K11071,K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 437.0
HKD3_k127_1278556_5 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 376.0
HKD3_k127_1278556_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 330.0
HKD3_k127_1278556_7 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000000001403 199.0
HKD3_k127_1278556_8 import inner membrane translocase subunit Tim44 - - - 0.000000000000000000000000000000000000000000000006933 195.0
HKD3_k127_1278556_9 Belongs to the acetyltransferase family. ArgA subfamily K03830 - - 0.0000000000000000000000000000000000007907 147.0
HKD3_k127_130180_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 4.077e-219 709.0
HKD3_k127_130180_1 PFAM Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 562.0
HKD3_k127_130180_10 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 346.0
HKD3_k127_130180_11 PFAM ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 328.0
HKD3_k127_130180_12 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 342.0
HKD3_k127_130180_13 phenazine biosynthesis protein PhzF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 317.0
HKD3_k127_130180_14 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 300.0
HKD3_k127_130180_15 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 296.0
HKD3_k127_130180_16 Iron permease K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 298.0
HKD3_k127_130180_17 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 306.0
HKD3_k127_130180_18 abc transporter atp-binding protein K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 291.0
HKD3_k127_130180_19 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000004004 264.0
HKD3_k127_130180_2 PFAM Transketolase central region K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 547.0
HKD3_k127_130180_20 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000002746 253.0
HKD3_k127_130180_21 sodium ABC transporter, permease K09696 - - 0.00000000000000000000000000000000000000000000000000000000000000118 233.0
HKD3_k127_130180_22 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000617 228.0
HKD3_k127_130180_23 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000002321 218.0
HKD3_k127_130180_24 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000533 209.0
HKD3_k127_130180_25 TPM domain - - - 0.00000000000000000000000000000000000000000000008237 173.0
HKD3_k127_130180_26 PFAM globin K06886 - - 0.000000000000000000000000000000000000005389 169.0
HKD3_k127_130180_27 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000001663 106.0
HKD3_k127_130180_28 Cupredoxin-like domain - - - 0.00000000000000000000005866 102.0
HKD3_k127_130180_29 Competence protein ComEA K02237 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.000000000000000000001798 108.0
HKD3_k127_130180_3 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 529.0
HKD3_k127_130180_30 Competence protein ComEA K02237 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.00000000000000000001195 102.0
HKD3_k127_130180_31 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000002698 82.0
HKD3_k127_130180_4 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 477.0
HKD3_k127_130180_5 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 458.0
HKD3_k127_130180_6 PFAM alpha beta hydrolase fold K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 422.0
HKD3_k127_130180_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 393.0
HKD3_k127_130180_8 Rhodanese Homology Domain K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 367.0
HKD3_k127_130180_9 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 346.0
HKD3_k127_1311593_0 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 315.0
HKD3_k127_1311593_1 prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000852 290.0
HKD3_k127_1311593_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000009507 173.0
HKD3_k127_1324619_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 447.0
HKD3_k127_1324619_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 429.0
HKD3_k127_1324619_2 Ribosomal L32p protein family K02911 - - 0.00000000000000000000000000001352 118.0
HKD3_k127_1324619_3 Malonyl CoA-acyl carrier protein transacylase K00645,K15355 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.0000005163 55.0
HKD3_k127_1334530_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.63e-279 895.0
HKD3_k127_1334530_1 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 7.264e-219 685.0
HKD3_k127_1334530_10 Urocanase C-terminal domain - - - 0.000005945 49.0
HKD3_k127_1334530_2 Carbohydrate transport and metabolism K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 600.0
HKD3_k127_1334530_3 Catalyzes the degradation of histidine to urocanate and ammmonia K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 577.0
HKD3_k127_1334530_4 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 502.0
HKD3_k127_1334530_5 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 428.0
HKD3_k127_1334530_6 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 433.0
HKD3_k127_1334530_7 MASE1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001628 261.0
HKD3_k127_1334530_8 Tripartite ATP-independent periplasmic transporter dctq component - - - 0.00000000000000000000000000000000000000000000000000000000000000000003482 252.0
HKD3_k127_1334530_9 Two component transcriptional regulator, LuxR family K13041 - - 0.00000000000000000000000000000000000000000000009758 183.0
HKD3_k127_1358856_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 1.241e-208 667.0
HKD3_k127_1358856_1 Subtilase family - - - 2.08e-207 695.0
HKD3_k127_1358856_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 619.0
HKD3_k127_1358856_3 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 511.0
HKD3_k127_1382149_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 7.815e-311 983.0
HKD3_k127_1382149_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 4.335e-304 943.0
HKD3_k127_1382149_2 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 9.932e-255 797.0
HKD3_k127_1382149_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02017,K02052 - 3.6.3.29,3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 471.0
HKD3_k127_1382149_4 involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 342.0
HKD3_k127_1382149_5 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 332.0
HKD3_k127_1382149_6 Pfam:AmoA K07120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001333 284.0
HKD3_k127_1382149_7 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002657 265.0
HKD3_k127_1382149_8 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000001062 260.0
HKD3_k127_1382149_9 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000003829 214.0
HKD3_k127_1383983_0 4-hydroxyphenylacetate K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 6.559e-208 684.0
HKD3_k127_1383983_1 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 612.0
HKD3_k127_1383983_2 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 495.0
HKD3_k127_1383983_3 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000001326 175.0
HKD3_k127_1383983_4 phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000215 143.0
HKD3_k127_1386485_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 8.105e-226 706.0
HKD3_k127_1386485_1 Conserved carboxylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 579.0
HKD3_k127_1386485_10 Protein of unknown function DUF126 K09128 - - 0.00000000000000000000000000000000000000000000000000191 201.0
HKD3_k127_1386485_11 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000005294 131.0
HKD3_k127_1386485_12 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000001648 119.0
HKD3_k127_1386485_13 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000003958 96.0
HKD3_k127_1386485_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 563.0
HKD3_k127_1386485_3 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 528.0
HKD3_k127_1386485_4 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 434.0
HKD3_k127_1386485_5 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 410.0
HKD3_k127_1386485_6 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 362.0
HKD3_k127_1386485_7 KR domain K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 325.0
HKD3_k127_1386485_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002818 277.0
HKD3_k127_1386485_9 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000001321 258.0
HKD3_k127_1420876_0 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001258 277.0
HKD3_k127_1420876_1 Pfam Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000000001271 149.0
HKD3_k127_1420876_2 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000866 146.0
HKD3_k127_145075_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 438.0
HKD3_k127_145075_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 389.0
HKD3_k127_145075_2 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 379.0
HKD3_k127_145075_3 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.00000000000000000000000051 108.0
HKD3_k127_145075_4 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000001066 87.0
HKD3_k127_1453916_0 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 8.841e-276 867.0
HKD3_k127_1453916_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 344.0
HKD3_k127_1453916_2 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003701 274.0
HKD3_k127_1453916_3 LysE type translocator K05834 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004931 263.0
HKD3_k127_1453916_4 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000002386 229.0
HKD3_k127_1453916_5 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000008199 191.0
HKD3_k127_1483261_0 oxidoreductase activity - - - 0.0 1087.0
HKD3_k127_1483261_1 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 592.0
HKD3_k127_1483261_2 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002447 262.0
HKD3_k127_1483261_3 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000002496 184.0
HKD3_k127_1483261_4 - - - - 0.0000000000000000000000000003006 119.0
HKD3_k127_1483261_5 Belongs to the DapA family K01714,K13876 - 4.2.1.43,4.3.3.7 0.00000000001242 77.0
HKD3_k127_1574815_0 AcrB/AcrD/AcrF family - - - 0.0 1306.0
HKD3_k127_1574815_1 molybdopterin cofactor binding K08352 - 1.8.5.5 5.291e-316 984.0
HKD3_k127_1574815_10 Protein of unknown function (DUF2892) - - - 0.000000000000000000002824 104.0
HKD3_k127_1574815_11 Protein of unknown function (DUF2892) - - - 0.000000000000000746 85.0
HKD3_k127_1574815_2 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 2.381e-225 703.0
HKD3_k127_1574815_3 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 449.0
HKD3_k127_1574815_4 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 307.0
HKD3_k127_1574815_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007563 285.0
HKD3_k127_1574815_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006562 276.0
HKD3_k127_1574815_7 - K07112 - - 0.00000000000000000000000000000000000000002529 162.0
HKD3_k127_1574815_8 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000001783 151.0
HKD3_k127_1574815_9 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K07112 - - 0.000000000000000000000000000000000000002981 161.0
HKD3_k127_1628375_0 PfkB domain protein K03338 - 2.7.1.92 1.039e-295 925.0
HKD3_k127_1628375_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K03336 - 3.7.1.22 1.209e-273 879.0
HKD3_k127_1628375_2 EamA-like transporter family K15268 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001179 264.0
HKD3_k127_1628375_3 Xylose isomerase-like TIM barrel - - - 0.000000000000002141 86.0
HKD3_k127_1628375_4 Transporter - - - 0.00000003393 57.0
HKD3_k127_1686692_0 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 472.0
HKD3_k127_1686692_1 Pyridine nucleotide-disulfide oxidoreductase domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 431.0
HKD3_k127_1686692_2 Ubiquinone biosynthesis hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 325.0
HKD3_k127_1686692_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 315.0
HKD3_k127_1686692_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000174 277.0
HKD3_k127_1686692_5 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005972 249.0
HKD3_k127_1686692_6 Disulfide bond isomerase protein N-terminus K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000001409 240.0
HKD3_k127_1686692_7 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000269 198.0
HKD3_k127_1686692_8 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000000000000003142 174.0
HKD3_k127_1692703_0 DNA polymerase X family K02347 - - 1.901e-235 744.0
HKD3_k127_1692703_1 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 1.461e-226 709.0
HKD3_k127_1692703_10 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000005297 237.0
HKD3_k127_1692703_11 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000002074 181.0
HKD3_k127_1692703_12 - - - - 0.000000000000000000000000000000000000000000000007927 198.0
HKD3_k127_1692703_13 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000003024 173.0
HKD3_k127_1692703_14 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000007367 154.0
HKD3_k127_1692703_15 AntiSigma factor - - - 0.0000000000000000000000000000000000003035 156.0
HKD3_k127_1692703_16 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000006309 125.0
HKD3_k127_1692703_17 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000000008596 119.0
HKD3_k127_1692703_18 - - - - 0.000000000000000001033 87.0
HKD3_k127_1692703_19 EamA-like transporter family - - - 0.00000000000001104 84.0
HKD3_k127_1692703_2 Protein tyrosine kinase K12132 - 2.7.11.1 1.544e-216 699.0
HKD3_k127_1692703_20 EamA-like transporter family - - - 0.00000008862 59.0
HKD3_k127_1692703_21 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.000002134 56.0
HKD3_k127_1692703_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 550.0
HKD3_k127_1692703_4 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 479.0
HKD3_k127_1692703_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 441.0
HKD3_k127_1692703_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 403.0
HKD3_k127_1692703_7 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 406.0
HKD3_k127_1692703_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 333.0
HKD3_k127_1692703_9 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 338.0
HKD3_k127_1716716_0 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 7.251e-261 814.0
HKD3_k127_1716716_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 8.018e-237 747.0
HKD3_k127_1716716_10 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000004115 231.0
HKD3_k127_1716716_11 Ferredoxin K05337 - - 0.00000000000000000000000000000003532 128.0
HKD3_k127_1716716_12 CBS domain - - - 0.000000000000000000003545 99.0
HKD3_k127_1716716_2 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 580.0
HKD3_k127_1716716_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 473.0
HKD3_k127_1716716_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 453.0
HKD3_k127_1716716_5 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 355.0
HKD3_k127_1716716_6 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 374.0
HKD3_k127_1716716_7 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004642 278.0
HKD3_k127_1716716_8 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000002965 276.0
HKD3_k127_1716716_9 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000009236 238.0
HKD3_k127_1818573_0 Chloramphenicol phosphotransferase-like protein K18554 - - 0.000000000000000000000000000000000000000000000000000000000000007371 221.0
HKD3_k127_1818573_1 IclR family transcriptional regulator K02624,K13641,K20539 - - 0.000000000000000000000000000000000000000000000000001472 187.0
HKD3_k127_1818573_2 Cytochrome c K08738 - - 0.00000000000000000000002589 111.0
HKD3_k127_1818573_3 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.0000000000000000006473 88.0
HKD3_k127_1882453_0 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 586.0
HKD3_k127_1882453_1 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 377.0
HKD3_k127_1882453_2 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 344.0
HKD3_k127_1882453_3 negative regulation of DNA-templated transcription, initiation K02616 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006082,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006805,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010124,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010817,GO:0016054,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043170,GO:0043254,GO:0043436,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0098754,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006502 262.0
HKD3_k127_1926591_0 oxidoreductase K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 429.0
HKD3_k127_1926591_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 391.0
HKD3_k127_1926591_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003157 263.0
HKD3_k127_1926591_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000002394 123.0
HKD3_k127_19520_0 Belongs to the DapA family K01714,K13876 - 4.2.1.43,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 480.0
HKD3_k127_19520_1 Lanthionine synthetase C-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 301.0
HKD3_k127_1955007_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1526.0
HKD3_k127_1955007_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 1.471e-231 722.0
HKD3_k127_1955007_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 596.0
HKD3_k127_1997871_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 545.0
HKD3_k127_1997871_1 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 310.0
HKD3_k127_1997871_2 Psort location Cytoplasmic, score K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000002599 192.0
HKD3_k127_2054371_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 9.801e-308 955.0
HKD3_k127_2054371_1 aminopeptidase N K01263 - 3.4.11.14 0.0000000000000000000000000000000000000000000001836 181.0
HKD3_k127_2152730_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.399e-202 638.0
HKD3_k127_2152730_1 Protein of unknown function (DUF3141) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 486.0
HKD3_k127_2152730_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 295.0
HKD3_k127_2152730_3 PFAM LrgB family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006625 274.0
HKD3_k127_2152730_4 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000001605 199.0
HKD3_k127_2152730_5 Cytochrome B561 - - - 0.000000000000000000000000000000000000000000004424 174.0
HKD3_k127_2152730_6 PFAM cytochrome c - - - 0.000000000000000000000000000000001181 135.0
HKD3_k127_2152730_7 effector of murein hydrolase LrgA K06518 - - 0.000000000000000000000003955 109.0
HKD3_k127_2152730_9 - - - - 0.000000002878 71.0
HKD3_k127_2315365_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 522.0
HKD3_k127_2315365_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 490.0
HKD3_k127_2315365_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002613 255.0
HKD3_k127_2315365_3 Molybdopterin-guanine dinucleotide biosynthesis protein MobA K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000008807 186.0
HKD3_k127_241799_0 His Kinase A (phosphoacceptor) domain - - - 7.304e-209 687.0
HKD3_k127_241799_1 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 331.0
HKD3_k127_2441161_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000002721 257.0
HKD3_k127_2441161_1 methyltransferase K03437 - - 0.000000000000000000000000000000000000000000000000000000003121 209.0
HKD3_k127_2441161_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000000000007966 130.0
HKD3_k127_24426_0 Efflux pump K03296,K18138,K18322 - - 0.0 1503.0
HKD3_k127_24426_1 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 496.0
HKD3_k127_24426_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 469.0
HKD3_k127_24426_3 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 467.0
HKD3_k127_24426_4 PFAM Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 421.0
HKD3_k127_24426_5 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007144 241.0
HKD3_k127_24426_6 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000000000000000000000000000000085 188.0
HKD3_k127_2454918_0 Belongs to the TPP enzyme family K03852 - 2.3.3.15 3.143e-278 867.0
HKD3_k127_2454918_1 GMC oxidoreductase K00108 - 1.1.99.1 1.019e-243 762.0
HKD3_k127_2454918_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 604.0
HKD3_k127_2454918_3 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 454.0
HKD3_k127_2454918_4 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 372.0
HKD3_k127_2454918_5 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 361.0
HKD3_k127_2454918_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000003145 141.0
HKD3_k127_2454918_7 succinate dehydrogenase K00247 - - 0.000000000000000000000000000008719 127.0
HKD3_k127_2454918_8 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.000000000000000000000001569 116.0
HKD3_k127_2454918_9 Tartrate K01677 - 4.2.1.2 0.00000000000001044 83.0
HKD3_k127_2462867_0 FAD linked oxidases, C-terminal domain - - - 0.0 1253.0
HKD3_k127_2462867_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1157.0
HKD3_k127_2462867_10 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 516.0
HKD3_k127_2462867_11 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 364.0
HKD3_k127_2462867_12 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 345.0
HKD3_k127_2462867_13 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 350.0
HKD3_k127_2462867_14 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 342.0
HKD3_k127_2462867_15 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 319.0
HKD3_k127_2462867_16 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 317.0
HKD3_k127_2462867_17 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 315.0
HKD3_k127_2462867_18 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002038 269.0
HKD3_k127_2462867_19 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005054 269.0
HKD3_k127_2462867_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1061.0
HKD3_k127_2462867_20 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001696 251.0
HKD3_k127_2462867_21 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000003238 221.0
HKD3_k127_2462867_22 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000008478 185.0
HKD3_k127_2462867_23 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000006691 165.0
HKD3_k127_2462867_24 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000002563 154.0
HKD3_k127_2462867_25 - - - - 0.0000000000000000000000000000000000000007236 159.0
HKD3_k127_2462867_26 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000001811 145.0
HKD3_k127_2462867_27 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000166 122.0
HKD3_k127_2462867_28 Predicted integral membrane protein (DUF2269) - - - 0.000000000000000000000000005088 119.0
HKD3_k127_2462867_29 - - - - 0.00000000000000000000000069 121.0
HKD3_k127_2462867_3 Elongation factor G, domain IV K02355 - - 3.943e-299 932.0
HKD3_k127_2462867_30 Protein of unknown function (DUF2782) - - - 0.00000000000000004017 85.0
HKD3_k127_2462867_4 Helicase K03657 - 3.6.4.12 4.78e-294 923.0
HKD3_k127_2462867_5 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 2.738e-259 834.0
HKD3_k127_2462867_6 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 598.0
HKD3_k127_2462867_7 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 596.0
HKD3_k127_2462867_8 dihydroorotase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 578.0
HKD3_k127_2462867_9 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 537.0
HKD3_k127_2500259_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1235.0
HKD3_k127_2502701_0 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 8.782e-216 677.0
HKD3_k127_2502701_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 453.0
HKD3_k127_2502701_10 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000009142 197.0
HKD3_k127_2502701_11 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000000001407 177.0
HKD3_k127_2502701_12 Cysteine-rich CWC - - - 0.00000000000001809 76.0
HKD3_k127_2502701_13 Pentapeptide repeats (9 copies) - - - 0.0000006085 55.0
HKD3_k127_2502701_2 PEP-CTERM motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 432.0
HKD3_k127_2502701_3 ribonuclease BN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 351.0
HKD3_k127_2502701_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 317.0
HKD3_k127_2502701_5 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 295.0
HKD3_k127_2502701_6 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001132 274.0
HKD3_k127_2502701_7 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002644 263.0
HKD3_k127_2502701_8 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006635 257.0
HKD3_k127_2502701_9 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000002552 199.0
HKD3_k127_2522251_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 9.792e-286 894.0
HKD3_k127_2522251_1 Proton-conducting membrane transporter - - - 1.428e-278 870.0
HKD3_k127_2522251_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 559.0
HKD3_k127_2522251_3 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 361.0
HKD3_k127_2522251_4 NADH dehydrogenase - - - 0.0000000000000000000004211 113.0
HKD3_k127_2561670_0 Superfamily I DNA and RNA helicases K03657 - 3.6.4.12 1.681e-287 901.0
HKD3_k127_2561670_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 343.0
HKD3_k127_2561670_2 Beta/gamma crystallins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002043 253.0
HKD3_k127_2561670_3 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000004191 199.0
HKD3_k127_2561670_4 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000000000000003307 186.0
HKD3_k127_2561670_5 PFAM aldo keto reductase - - - 0.0000000000001126 71.0
HKD3_k127_2625455_0 Predicted permease K07089 - - 2.058e-207 655.0
HKD3_k127_2625455_1 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000001949 204.0
HKD3_k127_2625455_2 Thioredoxin domain - - - 0.00000000000000000000003183 116.0
HKD3_k127_2625455_3 - - - - 0.0000001956 54.0
HKD3_k127_2734494_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 1.744e-251 785.0
HKD3_k127_2734494_1 provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate K00266 - 1.4.1.13,1.4.1.14 4.233e-243 767.0
HKD3_k127_2734494_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 334.0
HKD3_k127_2734494_3 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 316.0
HKD3_k127_2748853_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 606.0
HKD3_k127_2748853_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 529.0
HKD3_k127_2748853_2 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 500.0
HKD3_k127_2748853_3 FAD-dependent pyridine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 488.0
HKD3_k127_2748853_4 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 434.0
HKD3_k127_2748853_5 PFAM thiamineS protein - - - 0.0000000000000000000000000001218 116.0
HKD3_k127_2748853_6 peptidase S1 and S6 chymotrypsin Hap K01337 - 3.4.21.50 0.00000000000001257 84.0
HKD3_k127_2748853_7 - - - - 0.00000000003497 67.0
HKD3_k127_2769723_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 0.0 1007.0
HKD3_k127_2769723_1 nitrite transporter K02575 - - 7.83e-316 972.0
HKD3_k127_2769723_10 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 319.0
HKD3_k127_2769723_11 Response regulator receiver domain protein K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008858 261.0
HKD3_k127_2769723_12 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000006626 215.0
HKD3_k127_2769723_13 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000000000003091 113.0
HKD3_k127_2769723_15 amine dehydrogenase activity - - - 0.0000000001443 76.0
HKD3_k127_2769723_16 Domain of unknown function (DUF4118) - - - 0.000000002334 69.0
HKD3_k127_2769723_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.108e-297 926.0
HKD3_k127_2769723_3 Major Facilitator Superfamily K02575 - - 2.076e-215 675.0
HKD3_k127_2769723_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.875e-209 670.0
HKD3_k127_2769723_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.152e-198 632.0
HKD3_k127_2769723_6 Type IV pili methyl-accepting chemotaxis transducer N-term K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 543.0
HKD3_k127_2769723_7 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 511.0
HKD3_k127_2769723_8 nitrite transmembrane transporter activity K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 462.0
HKD3_k127_2769723_9 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 453.0
HKD3_k127_2791340_0 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22015 - 1.17.1.9,1.17.99.7 3.373e-299 939.0
HKD3_k127_2791340_1 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00122 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000007587 190.0
HKD3_k127_2897810_0 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 7.647e-320 1003.0
HKD3_k127_2897810_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.39e-233 731.0
HKD3_k127_2897810_10 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 321.0
HKD3_k127_2897810_11 dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000133 262.0
HKD3_k127_2897810_12 Belongs to the ComB family K05979 - 3.1.3.71 0.0000000000000000000000000000000000000000000000000000000000001045 221.0
HKD3_k127_2897810_13 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000001091 212.0
HKD3_k127_2897810_14 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000861 211.0
HKD3_k127_2897810_15 DoxX K15977 - - 0.00000000000000000000000000000000000000103 156.0
HKD3_k127_2897810_16 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000000000000000152 82.0
HKD3_k127_2897810_17 electron transfer activity K03737,K05337 - 1.2.7.1 0.00001132 59.0
HKD3_k127_2897810_2 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 7.952e-221 701.0
HKD3_k127_2897810_3 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 545.0
HKD3_k127_2897810_4 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 505.0
HKD3_k127_2897810_5 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 482.0
HKD3_k127_2897810_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 481.0
HKD3_k127_2897810_7 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 347.0
HKD3_k127_2897810_8 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 309.0
HKD3_k127_2897810_9 Two component transcriptional regulator, winged helix family K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 331.0
HKD3_k127_2930562_0 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 531.0
HKD3_k127_2930562_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000002799 188.0
HKD3_k127_2930562_2 Histidine kinase - - - 0.0000000000000000000000000000000000001488 163.0
HKD3_k127_2930562_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000008669 126.0
HKD3_k127_2930562_4 LytTr DNA-binding domain - - - 0.00000000000001408 74.0
HKD3_k127_2930562_5 Histidine kinase - - - 0.000000000016 73.0
HKD3_k127_2954176_0 FAD linked oxidase domain protein - - - 0.0 1802.0
HKD3_k127_2954176_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 496.0
HKD3_k127_2954176_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000005937 265.0
HKD3_k127_2954176_3 Cytochrome c - - - 0.0000002642 58.0
HKD3_k127_300053_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 466.0
HKD3_k127_300053_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 404.0
HKD3_k127_300053_10 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000001549 216.0
HKD3_k127_300053_11 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000003171 207.0
HKD3_k127_300053_12 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000005379 200.0
HKD3_k127_300053_13 n-acetyltransferase - - - 0.0000000000000000000000000000000000001869 159.0
HKD3_k127_300053_14 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000001115 111.0
HKD3_k127_300053_15 - - - - 0.0000000000000004438 86.0
HKD3_k127_300053_16 Domain of unknown function (DUF4936) - - - 0.00000000007407 74.0
HKD3_k127_300053_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 376.0
HKD3_k127_300053_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 362.0
HKD3_k127_300053_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 321.0
HKD3_k127_300053_5 proteins homologs of microcin C7 resistance protein MccF K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005005 289.0
HKD3_k127_300053_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001887 275.0
HKD3_k127_300053_7 glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000001289 269.0
HKD3_k127_300053_8 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000001358 236.0
HKD3_k127_300053_9 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000167 232.0
HKD3_k127_3045247_0 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 9.052e-213 679.0
HKD3_k127_3045247_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 546.0
HKD3_k127_3045247_10 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.000000000000000000000000000000000000000000000000004459 186.0
HKD3_k127_3045247_11 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000001922 173.0
HKD3_k127_3045247_12 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000144 169.0
HKD3_k127_3045247_13 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000003497 151.0
HKD3_k127_3045247_14 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000000000000000816 140.0
HKD3_k127_3045247_15 ribosomal subunit interface protein K05808 - - 0.000000000000000000000000000000001055 150.0
HKD3_k127_3045247_16 Transport permease protein K01992 - - 0.0000001356 58.0
HKD3_k127_3045247_17 STAS domain K07122 - - 0.00001085 57.0
HKD3_k127_3045247_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 406.0
HKD3_k127_3045247_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 399.0
HKD3_k127_3045247_4 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 385.0
HKD3_k127_3045247_5 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 373.0
HKD3_k127_3045247_6 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 376.0
HKD3_k127_3045247_7 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000002812 229.0
HKD3_k127_3045247_8 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000005216 222.0
HKD3_k127_3045247_9 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000006926 197.0
HKD3_k127_304627_0 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 609.0
HKD3_k127_304627_1 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 556.0
HKD3_k127_304627_10 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000003108 276.0
HKD3_k127_304627_11 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000001096 271.0
HKD3_k127_304627_12 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001333 246.0
HKD3_k127_304627_13 glycosyl transferase K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000002461 234.0
HKD3_k127_304627_14 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000004252 196.0
HKD3_k127_304627_15 Lactoylglutathione lyase - - - 0.0000000000000000000000000000000000000000000000000000007809 194.0
HKD3_k127_304627_16 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.00000000000000000000000000000000000000000000000002061 193.0
HKD3_k127_304627_17 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000000007693 185.0
HKD3_k127_304627_18 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000000001733 143.0
HKD3_k127_304627_19 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000003461 134.0
HKD3_k127_304627_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 522.0
HKD3_k127_304627_20 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000004137 109.0
HKD3_k127_304627_21 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000007622 109.0
HKD3_k127_304627_22 Transcriptional regulator - - - 0.0000000000001615 77.0
HKD3_k127_304627_23 PGAP1-like protein - - - 0.00000000005635 65.0
HKD3_k127_304627_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 439.0
HKD3_k127_304627_4 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 394.0
HKD3_k127_304627_5 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 384.0
HKD3_k127_304627_6 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 378.0
HKD3_k127_304627_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 342.0
HKD3_k127_304627_8 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 327.0
HKD3_k127_304627_9 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 317.0
HKD3_k127_3065318_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 552.0
HKD3_k127_3065318_1 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 515.0
HKD3_k127_3065318_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000007706 121.0
HKD3_k127_3065318_11 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000002003 88.0
HKD3_k127_3065318_2 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 514.0
HKD3_k127_3065318_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 425.0
HKD3_k127_3065318_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 407.0
HKD3_k127_3065318_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000034 297.0
HKD3_k127_3065318_6 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001661 275.0
HKD3_k127_3065318_7 Lysophospholipase L1 and related esterases K01073 - 3.1.2.20 0.0000000000000000000000000000000000000000000000008109 182.0
HKD3_k127_3065318_8 Acid phosphatase homologues - - - 0.00000000000000000000000000000000000000112 159.0
HKD3_k127_3065318_9 Lysin motif - - - 0.00000000000000000000000000000005485 139.0
HKD3_k127_320182_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1395.0
HKD3_k127_320182_1 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) K01484 - 3.5.3.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 524.0
HKD3_k127_320182_10 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000004163 137.0
HKD3_k127_320182_11 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000002212 130.0
HKD3_k127_320182_2 aminotransferase K00821,K00840 GO:0003674,GO:0003824,GO:0003992,GO:0004069,GO:0005488,GO:0005515,GO:0006082,GO:0006105,GO:0006520,GO:0006525,GO:0006526,GO:0006527,GO:0006553,GO:0006591,GO:0006593,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009016,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009067,GO:0009084,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0017144,GO:0019545,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0036094,GO:0042450,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043825,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.11,2.6.1.17,2.6.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 516.0
HKD3_k127_320182_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 421.0
HKD3_k127_320182_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 399.0
HKD3_k127_320182_5 Arginine N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 389.0
HKD3_k127_320182_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 357.0
HKD3_k127_320182_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 341.0
HKD3_k127_320182_8 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004436 256.0
HKD3_k127_320182_9 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000006917 187.0
HKD3_k127_3256084_0 AcyL-CoA dehydrogenase K06445 - - 0.0 1079.0
HKD3_k127_3256084_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 1.643e-255 799.0
HKD3_k127_3256084_10 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000000000000000000008151 171.0
HKD3_k127_3256084_11 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000001853 182.0
HKD3_k127_3256084_12 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000000000000004155 145.0
HKD3_k127_3256084_13 Long-chain fatty acid transport protein K06076 - - 0.000000004342 63.0
HKD3_k127_3256084_2 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.22e-249 786.0
HKD3_k127_3256084_3 Belongs to the thiolase family K00626 - 2.3.1.9 6.23e-216 679.0
HKD3_k127_3256084_4 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 465.0
HKD3_k127_3256084_5 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 426.0
HKD3_k127_3256084_6 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008217 287.0
HKD3_k127_3256084_7 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000004749 243.0
HKD3_k127_3256084_8 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000005702 237.0
HKD3_k127_3256084_9 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000009205 209.0
HKD3_k127_3288630_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.668e-212 670.0
HKD3_k127_335241_0 Acts as a magnesium transporter K06213 - - 4.56e-199 631.0
HKD3_k127_335241_1 NADH flavin oxidoreductase NADH oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 537.0
HKD3_k127_335241_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 303.0
HKD3_k127_335241_3 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006625 223.0
HKD3_k127_335241_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000000000000000000000000000000000000105 216.0
HKD3_k127_335241_5 - - - - 0.00000000000000000000000001591 116.0
HKD3_k127_343437_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 504.0
HKD3_k127_343437_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 421.0
HKD3_k127_343437_10 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000002073 224.0
HKD3_k127_343437_11 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000006756 209.0
HKD3_k127_343437_12 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000000002672 186.0
HKD3_k127_343437_2 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008812 396.0
HKD3_k127_343437_3 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 363.0
HKD3_k127_343437_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 371.0
HKD3_k127_343437_5 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 373.0
HKD3_k127_343437_6 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 332.0
HKD3_k127_343437_7 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 306.0
HKD3_k127_343437_8 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 307.0
HKD3_k127_343437_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000002059 233.0
HKD3_k127_356944_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 613.0
HKD3_k127_356944_1 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 456.0
HKD3_k127_356944_10 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000004872 209.0
HKD3_k127_356944_11 Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors K12973 - 2.3.1.251 0.000000000000000000000000000000000000003711 153.0
HKD3_k127_356944_12 Alpha/beta hydrolase family - - - 0.0000000000000000000004805 111.0
HKD3_k127_356944_13 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000002208 94.0
HKD3_k127_356944_14 - - - - 0.000000001822 69.0
HKD3_k127_356944_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 461.0
HKD3_k127_356944_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 470.0
HKD3_k127_356944_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 434.0
HKD3_k127_356944_5 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 395.0
HKD3_k127_356944_6 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 353.0
HKD3_k127_356944_7 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 361.0
HKD3_k127_356944_8 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 321.0
HKD3_k127_356944_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001786 279.0
HKD3_k127_3640430_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 365.0
HKD3_k127_3640430_1 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 354.0
HKD3_k127_3640430_2 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.00005983 53.0
HKD3_k127_3677793_0 phenylacetic acid degradation protein paaN - - - 4.173e-262 819.0
HKD3_k127_3677793_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.146e-210 662.0
HKD3_k127_3677793_2 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 544.0
HKD3_k127_3677793_3 Oxidoreductase FAD-binding domain K02613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 471.0
HKD3_k127_3677793_4 aminotransferase K09758 - 4.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 407.0
HKD3_k127_3677793_5 enoyl-CoA hydratase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 385.0
HKD3_k127_3677793_6 phenylacetic acid K02611 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 338.0
HKD3_k127_3677793_7 phenylacetate-CoA oxygenase, PaaJ subunit K02612 GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000166 220.0
HKD3_k127_3677793_8 Phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.0000000000000000000000000000000000000000000000000000002143 198.0
HKD3_k127_3677793_9 Phenylacetic acid degradation B K02610 - - 0.00000000000000000000000000000000000000000000000000008722 186.0
HKD3_k127_3685528_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1338.0
HKD3_k127_3685528_1 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 315.0
HKD3_k127_3685528_2 Universal stress protein family - - - 0.00000000000000000000000000000002203 137.0
HKD3_k127_3685528_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000003425 126.0
HKD3_k127_3691830_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 597.0
HKD3_k127_3691830_1 ABC transporter K02003 - - 0.00000000000000000000000000000149 123.0
HKD3_k127_3691830_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000001718 57.0
HKD3_k127_3725117_0 Binding-protein-dependent transport system inner membrane component K02011 - - 6.242e-264 832.0
HKD3_k127_3725117_1 COG1960 Acyl-CoA dehydrogenases K20035 - - 8.353e-247 775.0
HKD3_k127_3725117_10 Bacterial extracellular solute-binding protein K02012,K11081 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 374.0
HKD3_k127_3725117_11 LysR substrate binding domain K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 305.0
HKD3_k127_3725117_12 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003373 250.0
HKD3_k127_3725117_13 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000002417 220.0
HKD3_k127_3725117_14 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000001551 210.0
HKD3_k127_3725117_15 - - - - 0.00000000000000000000000000000000000000000000000000001174 211.0
HKD3_k127_3725117_16 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000007275 196.0
HKD3_k127_3725117_17 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000004854 169.0
HKD3_k127_3725117_18 Psort location Cytoplasmic, score 8.96 K07039 - - 0.00000000000000000000000000000007239 135.0
HKD3_k127_3725117_19 Serine aminopeptidase, S33 - - - 0.0000000000000002968 83.0
HKD3_k127_3725117_2 abc transporter K15738 - - 1.226e-205 673.0
HKD3_k127_3725117_20 exo-alpha-(2->6)-sialidase activity - - - 0.000000000006504 78.0
HKD3_k127_3725117_3 TrkA-N domain - - - 1.466e-195 627.0
HKD3_k127_3725117_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 481.0
HKD3_k127_3725117_5 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 465.0
HKD3_k127_3725117_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 419.0
HKD3_k127_3725117_7 PFAM ROK family protein K00845,K00847 - 2.7.1.2,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 421.0
HKD3_k127_3725117_8 electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 404.0
HKD3_k127_3725117_9 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 381.0
HKD3_k127_3739826_0 Protein of unknown function (DUF3141) - - - 0.0 1048.0
HKD3_k127_3739826_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 1.399e-230 733.0
HKD3_k127_3739826_10 NADP oxidoreductase coenzyme F420-dependent K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 419.0
HKD3_k127_3739826_11 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 400.0
HKD3_k127_3739826_12 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 333.0
HKD3_k127_3739826_13 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 313.0
HKD3_k127_3739826_14 response regulator K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 297.0
HKD3_k127_3739826_15 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004477 263.0
HKD3_k127_3739826_16 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004177 249.0
HKD3_k127_3739826_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000002482 231.0
HKD3_k127_3739826_18 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000449 200.0
HKD3_k127_3739826_19 membrane - - - 0.000000000000000000000000000000000000000000000066 193.0
HKD3_k127_3739826_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 3.177e-208 666.0
HKD3_k127_3739826_20 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.0000000000000000000000000000000000000000000003939 173.0
HKD3_k127_3739826_21 Protein of unknown function (DUF3302) - - - 0.00000000000000000000000000000000000000001267 162.0
HKD3_k127_3739826_22 - - - - 0.0000000000000000000000000000000000000003074 166.0
HKD3_k127_3739826_23 - - - - 0.00000000000000000000000000000000000383 144.0
HKD3_k127_3739826_24 Family of unknown function (DUF5329) - - - 0.00000000000000000000000000000000001573 138.0
HKD3_k127_3739826_25 Na( )-dependent transporter - - - 0.000000000000000000000004375 112.0
HKD3_k127_3739826_26 - - - - 0.00000000000000000000003446 104.0
HKD3_k127_3739826_27 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.0000001441 60.0
HKD3_k127_3739826_28 redox protein, regulator of disulfide bond formation K07397 - - 0.000006361 48.0
HKD3_k127_3739826_29 general secretion pathway protein - - - 0.000007611 51.0
HKD3_k127_3739826_3 phosphate K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 505.0
HKD3_k127_3739826_30 - - - - 0.0003415 49.0
HKD3_k127_3739826_4 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 431.0
HKD3_k127_3739826_5 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 448.0
HKD3_k127_3739826_6 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 426.0
HKD3_k127_3739826_7 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 420.0
HKD3_k127_3739826_8 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 439.0
HKD3_k127_3739826_9 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 435.0
HKD3_k127_3780575_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 519.0
HKD3_k127_3780575_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 433.0
HKD3_k127_3780575_10 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 319.0
HKD3_k127_3780575_11 Shikimate dehydrogenase substrate binding domain protein K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 307.0
HKD3_k127_3780575_12 amino acid K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 308.0
HKD3_k127_3780575_13 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001288 291.0
HKD3_k127_3780575_14 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000002715 278.0
HKD3_k127_3780575_15 2-keto-4-pentenoate hydratase K02554 - 4.2.1.80 0.0000000000000000000000000000000000003241 159.0
HKD3_k127_3780575_16 - K11477 - - 0.000000000000000000000000000001793 128.0
HKD3_k127_3780575_2 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 435.0
HKD3_k127_3780575_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 385.0
HKD3_k127_3780575_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 377.0
HKD3_k127_3780575_5 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 361.0
HKD3_k127_3780575_6 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009955 352.0
HKD3_k127_3780575_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 350.0
HKD3_k127_3780575_8 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 346.0
HKD3_k127_3780575_9 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 340.0
HKD3_k127_3795946_0 Bacterial sugar transferase K03606 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 416.0
HKD3_k127_3795946_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001431 253.0
HKD3_k127_3795946_2 - - - - 0.000000000000000000000000000000000000000000000000018 201.0
HKD3_k127_3795946_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000193 180.0
HKD3_k127_3795946_4 - - - - 0.00000000000000000000000000000000593 144.0
HKD3_k127_3795946_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000309 60.0
HKD3_k127_3795946_6 transferase activity, transferring glycosyl groups - - - 0.0006667 44.0
HKD3_k127_3823209_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 578.0
HKD3_k127_3823209_1 binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 417.0
HKD3_k127_3823209_2 taurine ABC transporter, periplasmic binding protein K15551 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 423.0
HKD3_k127_3823209_3 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K10831 - 3.6.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 384.0
HKD3_k127_3823209_4 COG1226 Kef-type K transport systems K10716 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000001233 167.0
HKD3_k127_3823209_5 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.0000000000000000000002603 98.0
HKD3_k127_3823759_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 497.0
HKD3_k127_3823759_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 375.0
HKD3_k127_3823759_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000008484 238.0
HKD3_k127_3823759_3 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.0000000000000000001617 91.0
HKD3_k127_3865446_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 287.0
HKD3_k127_3865446_1 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 288.0
HKD3_k127_3865446_2 PFAM peptidase S16 lon domain protein K07157 - - 0.00000001324 66.0
HKD3_k127_3882575_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 9.143e-194 613.0
HKD3_k127_3882575_1 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000554 603.0
HKD3_k127_3882575_2 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 492.0
HKD3_k127_3882575_3 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01032 - 2.8.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 459.0
HKD3_k127_3882575_4 MCM2/3/5 family K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 448.0
HKD3_k127_3882575_5 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000001053 184.0
HKD3_k127_3882575_6 COG0017 Aspartyl asparaginyl-tRNA synthetases K01893 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.000000000003314 66.0
HKD3_k127_3889242_0 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 1.968e-267 831.0
HKD3_k127_3889242_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 6.143e-249 782.0
HKD3_k127_3889242_10 Cytochrome c oxidase, subunit K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 379.0
HKD3_k127_3889242_11 ArgK protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 359.0
HKD3_k127_3889242_12 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 336.0
HKD3_k127_3889242_13 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 338.0
HKD3_k127_3889242_14 General secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 329.0
HKD3_k127_3889242_15 Methylmalonyl-CoA mutase K01848,K20906 - 5.4.99.2,5.4.99.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 290.0
HKD3_k127_3889242_16 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 303.0
HKD3_k127_3889242_17 PFAM 20S proteasome, A and B subunits K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001688 253.0
HKD3_k127_3889242_18 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007562 228.0
HKD3_k127_3889242_19 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000111 208.0
HKD3_k127_3889242_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 1.428e-239 749.0
HKD3_k127_3889242_20 COG2185 Methylmalonyl-CoA mutase, C-terminal domain subunit (cobalamin-binding) K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000000000434 202.0
HKD3_k127_3889242_21 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000005415 211.0
HKD3_k127_3889242_22 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000005812 186.0
HKD3_k127_3889242_23 B12 binding domain K22491 - - 0.000000000000000000000000000000000000000001692 173.0
HKD3_k127_3889242_24 - - - - 0.000000000000000000000000000000000000000957 168.0
HKD3_k127_3889242_25 universal stress protein - - - 0.0000000000000000000000000000000000001581 146.0
HKD3_k127_3889242_26 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000282 150.0
HKD3_k127_3889242_27 - - - - 0.000000000000000000000000000000004367 139.0
HKD3_k127_3889242_28 FixH family K09926 - - 0.0000000000000000000000000009359 130.0
HKD3_k127_3889242_29 PFAM RNA-binding S4 domain protein K04762 - - 0.000000000000000000000000007143 117.0
HKD3_k127_3889242_3 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.412e-231 728.0
HKD3_k127_3889242_30 - - - - 0.000000000000000000000007813 112.0
HKD3_k127_3889242_31 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000000000000008851 109.0
HKD3_k127_3889242_32 - - - - 0.000000000000000000000601 109.0
HKD3_k127_3889242_33 cytochrome oxidase maturation protein cbb3-type - - - 0.00000000000005881 76.0
HKD3_k127_3889242_34 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.0000003013 54.0
HKD3_k127_3889242_4 cation transport ATPase K01533 - 3.6.3.4 9.905e-218 703.0
HKD3_k127_3889242_5 cytochrome C oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 615.0
HKD3_k127_3889242_6 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 589.0
HKD3_k127_3889242_7 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 497.0
HKD3_k127_3889242_8 secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 479.0
HKD3_k127_3889242_9 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 419.0
HKD3_k127_3908525_0 Efflux pump membrane transporter K03296,K18138 - - 0.0 1224.0
HKD3_k127_3908525_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 586.0
HKD3_k127_3908525_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 423.0
HKD3_k127_3908525_3 PFAM HupH hydrogenase expression protein K03618 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004215 250.0
HKD3_k127_3908525_4 LssY C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000001372 241.0
HKD3_k127_3908525_5 Hydrogenase expression formation protein K03605 - - 0.00000000000000000000000000000000000000000000000000000000000000002241 229.0
HKD3_k127_3908525_6 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000000000008494 220.0
HKD3_k127_3908525_7 Hydrogenase-1 expression protein HyaE K03619 - - 0.0000000000000000000000000001625 128.0
HKD3_k127_3908525_8 Rubredoxin - - - 0.000000000000000000000003424 103.0
HKD3_k127_3908525_9 HupF/HypC family K04653 - - 0.00000000000000000000002641 103.0
HKD3_k127_3921486_0 acyl-CoA transferases carnitine dehydratase K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 505.0
HKD3_k127_3921486_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000006105 114.0
HKD3_k127_3946909_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1090.0
HKD3_k127_3946909_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1039.0
HKD3_k127_3946909_10 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002022 268.0
HKD3_k127_3946909_11 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003553 263.0
HKD3_k127_3946909_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K16049 - 1.13.11.25 0.00000000000000000000000000000000000000000000000000000000000000000000001764 252.0
HKD3_k127_3946909_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000003568 246.0
HKD3_k127_3946909_14 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000000001791 224.0
HKD3_k127_3946909_15 NUDIX domain K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000000000000002323 202.0
HKD3_k127_3946909_16 Beta/gamma crystallins - - - 0.0000000000000000000000000000000000000000000000004854 192.0
HKD3_k127_3946909_17 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000461 188.0
HKD3_k127_3946909_18 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000122 173.0
HKD3_k127_3946909_19 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000000000007195 184.0
HKD3_k127_3946909_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.236e-288 895.0
HKD3_k127_3946909_20 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000000111 146.0
HKD3_k127_3946909_21 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000006732 144.0
HKD3_k127_3946909_22 guanine-specific ribonuclease N1 and T1 K01167 - 3.1.27.3 0.000000000000000000000000000000001365 150.0
HKD3_k127_3946909_23 - - - - 0.00000000000000000000000000000001203 131.0
HKD3_k127_3946909_24 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000000002475 118.0
HKD3_k127_3946909_25 Regulatory protein, FmdB family - - - 0.00000000000000000000000001732 113.0
HKD3_k127_3946909_26 Barstar (barnase inhibitor) - - - 0.0000000000000000003168 92.0
HKD3_k127_3946909_27 Protein of unknown function (DUF541) - - - 0.0000000000000002535 92.0
HKD3_k127_3946909_28 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0005687 47.0
HKD3_k127_3946909_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 9.865e-228 722.0
HKD3_k127_3946909_4 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.566e-215 674.0
HKD3_k127_3946909_5 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 497.0
HKD3_k127_3946909_6 C-terminal region of band_7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 434.0
HKD3_k127_3946909_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K08683 - 1.1.1.178,1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 333.0
HKD3_k127_3946909_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 295.0
HKD3_k127_3946909_9 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000907 274.0
HKD3_k127_3954964_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1737.0
HKD3_k127_3954964_1 Belongs to the glycosyl hydrolase 13 family K02438 - 3.2.1.196 0.0 1351.0
HKD3_k127_3954964_10 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 427.0
HKD3_k127_3954964_11 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008876 351.0
HKD3_k127_3954964_12 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004457 292.0
HKD3_k127_3954964_13 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003313 277.0
HKD3_k127_3954964_14 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002188 258.0
HKD3_k127_3954964_15 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001885 253.0
HKD3_k127_3954964_16 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000003071 261.0
HKD3_k127_3954964_17 Nitrile hydratase beta subunit - - - 0.00000000000000000000000000000000000000000000000001804 192.0
HKD3_k127_3954964_18 protein conserved in bacteria K09796 - - 0.000000000000000000000000000000000000001392 154.0
HKD3_k127_3954964_19 TraB family K09973 - - 0.000000000000000000000000000000000000004802 163.0
HKD3_k127_3954964_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1178.0
HKD3_k127_3954964_20 TIGRFAM yecA family protein K07039 - - 0.00000000000000000000000000000000008747 145.0
HKD3_k127_3954964_21 Anaerobic ribonucleoside-triphosphate reductase - - - 0.0000000000000000000003924 98.0
HKD3_k127_3954964_22 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000003141 78.0
HKD3_k127_3954964_23 ADP-ribosyl- dinitrogen reductase hydrolase - - - 0.0000000002189 62.0
HKD3_k127_3954964_3 Ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1121.0
HKD3_k127_3954964_4 Tricorn protease homolog K08676 - - 0.0 1089.0
HKD3_k127_3954964_5 oligoendopeptidase F K08602 - - 1.346e-220 700.0
HKD3_k127_3954964_6 Nucleotidyl transferase K00975 - 2.7.7.27 3.121e-212 667.0
HKD3_k127_3954964_7 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 605.0
HKD3_k127_3954964_8 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 500.0
HKD3_k127_3954964_9 ABC-type dipeptide transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 497.0
HKD3_k127_3961878_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 9.23e-297 955.0
HKD3_k127_3961878_1 transport systems, ATPase components K02056 - 3.6.3.17 3.224e-210 672.0
HKD3_k127_3961878_10 ABC-type amino acid transport signal transduction systems periplasmic component domain K10001 GO:0003333,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015740,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016595,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070335,GO:0070778,GO:0071702,GO:0071705,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000002855 224.0
HKD3_k127_3961878_11 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000001142 186.0
HKD3_k127_3961878_12 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.000000000000000000006433 93.0
HKD3_k127_3961878_13 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000004956 89.0
HKD3_k127_3961878_14 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000001439 76.0
HKD3_k127_3961878_15 Glycine zipper 2TM domain - - - 0.00000001443 63.0
HKD3_k127_3961878_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 564.0
HKD3_k127_3961878_3 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 511.0
HKD3_k127_3961878_4 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 469.0
HKD3_k127_3961878_5 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 367.0
HKD3_k127_3961878_6 PFAM ABC transporter related K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 307.0
HKD3_k127_3961878_7 Mammalian cell entry related domain protein K02067,K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000142 266.0
HKD3_k127_3961878_8 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003638 267.0
HKD3_k127_3961878_9 ABC-type amino acid transport signal transduction systems periplasmic component domain K10001 GO:0003333,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015740,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016595,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070335,GO:0070778,GO:0071702,GO:0071705,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000004706 226.0
HKD3_k127_3968560_0 Required for chromosome condensation and partitioning K03529 - - 5.262e-297 949.0
HKD3_k127_3968560_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.531e-264 839.0
HKD3_k127_3968560_10 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000000000000000000000000000000003614 220.0
HKD3_k127_3968560_11 MarC family integral membrane protein - - - 0.0000000000000000000000000000000001084 139.0
HKD3_k127_3968560_2 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 529.0
HKD3_k127_3968560_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 461.0
HKD3_k127_3968560_4 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 467.0
HKD3_k127_3968560_5 Belongs to the ABC transporter superfamily K02032,K12372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 449.0
HKD3_k127_3968560_6 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 433.0
HKD3_k127_3968560_7 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 383.0
HKD3_k127_3968560_8 Transcriptional regulator, LysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 366.0
HKD3_k127_3968560_9 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004096 286.0
HKD3_k127_4042207_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 539.0
HKD3_k127_4042207_1 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 484.0
HKD3_k127_4042207_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 368.0
HKD3_k127_4042207_3 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 327.0
HKD3_k127_4042207_4 glycosylase K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000001904 184.0
HKD3_k127_4042207_5 membrane - - - 0.0000000000000000001294 91.0
HKD3_k127_4046778_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009991 474.0
HKD3_k127_4046778_1 phosphohistidine phosphatase K08296 - - 0.0000000000000000000000000000000000000000000000007293 194.0
HKD3_k127_4059292_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1262.0
HKD3_k127_4059292_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 583.0
HKD3_k127_4059292_10 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000007973 160.0
HKD3_k127_4059292_11 transcriptional regulator - - - 0.00000000000000000000000000000000000005098 151.0
HKD3_k127_4059292_12 Cobalt uptake substrate-specific transmembrane region - - - 0.0000000000000000000000000000542 128.0
HKD3_k127_4059292_13 Invasion gene expression up-regulator, SirB - - - 0.00000000000000000001141 99.0
HKD3_k127_4059292_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 399.0
HKD3_k127_4059292_3 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 356.0
HKD3_k127_4059292_4 4Fe-4S binding domain K18362 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 357.0
HKD3_k127_4059292_5 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.000000000000000000000000000000000000000000000000000000000000003037 224.0
HKD3_k127_4059292_6 DMSO reductase anchor subunit (DmsC) K18363 - - 0.000000000000000000000000000000000000000000000000002129 202.0
HKD3_k127_4059292_7 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000004541 178.0
HKD3_k127_4059292_8 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000001163 170.0
HKD3_k127_4059292_9 Thioesterase - - - 0.00000000000000000000000000000000000000000009471 168.0
HKD3_k127_4059882_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1043.0
HKD3_k127_4059882_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 5.181e-261 834.0
HKD3_k127_4059882_2 ABC-type multidrug transport system, ATPase and permease K06147 - - 3.616e-234 739.0
HKD3_k127_4059882_3 Aminotransferase class I and II K00832 - 2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 572.0
HKD3_k127_4059882_4 ABC-type dipeptide transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 468.0
HKD3_k127_4059882_5 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 368.0
HKD3_k127_4059882_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000175 207.0
HKD3_k127_4124782_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1349.0
HKD3_k127_4124782_1 Protein of unknown function, DUF255 - - - 3.491e-238 755.0
HKD3_k127_4124782_10 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 354.0
HKD3_k127_4124782_11 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000001448 257.0
HKD3_k127_4124782_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000881 224.0
HKD3_k127_4124782_13 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000009839 203.0
HKD3_k127_4124782_14 ApaG domain - - - 0.0000000000000000000000000000000000000000000000000003336 187.0
HKD3_k127_4124782_15 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000001626 185.0
HKD3_k127_4124782_16 Conserved protein of DIM6 NTAB family - - - 0.000000000000000000000000000000000000000000000002536 179.0
HKD3_k127_4124782_17 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000004623 130.0
HKD3_k127_4124782_18 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000002065 120.0
HKD3_k127_4124782_19 Cytochrome c K08738 - - 0.000000000000000000000000002846 117.0
HKD3_k127_4124782_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 555.0
HKD3_k127_4124782_20 - - - - 0.0000000000000000000004277 113.0
HKD3_k127_4124782_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 503.0
HKD3_k127_4124782_4 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 507.0
HKD3_k127_4124782_5 D-amino acid K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 481.0
HKD3_k127_4124782_6 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 439.0
HKD3_k127_4124782_7 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 449.0
HKD3_k127_4124782_8 Membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 423.0
HKD3_k127_4124782_9 Aminotransferase class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 377.0
HKD3_k127_4140477_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 533.0
HKD3_k127_4140477_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 424.0
HKD3_k127_4140477_2 preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000000002932 135.0
HKD3_k127_42602_0 Glucodextranase, domain N K01178 - 3.2.1.3 2.386e-321 1001.0
HKD3_k127_42602_1 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 1.433e-276 863.0
HKD3_k127_42602_11 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000001579 203.0
HKD3_k127_42602_12 hydrogenase maturation protease - - - 0.000000000000000000000000000000000001495 145.0
HKD3_k127_42602_13 DoxX K15977 - - 0.000000000000000000000000000001402 126.0
HKD3_k127_42602_14 protein import - - - 0.000000000000000000000000003223 128.0
HKD3_k127_42602_15 amine dehydrogenase activity - - - 0.0000000007471 72.0
HKD3_k127_42602_16 - - - - 0.0000000161 61.0
HKD3_k127_42602_17 Copper chaperone PCu(A)C K09796 - - 0.00000002172 62.0
HKD3_k127_42602_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 8.101e-246 767.0
HKD3_k127_42602_3 PFAM glutaredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 422.0
HKD3_k127_42602_4 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 392.0
HKD3_k127_42602_5 pfam abc1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 396.0
HKD3_k127_42602_6 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 363.0
HKD3_k127_42602_7 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 357.0
HKD3_k127_42602_8 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 376.0
HKD3_k127_42602_9 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 326.0
HKD3_k127_4356971_0 peptidase m48, ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 434.0
HKD3_k127_4356971_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009256 399.0
HKD3_k127_4356971_2 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005556 255.0
HKD3_k127_4356971_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000004851 137.0
HKD3_k127_43600_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 400.0
HKD3_k127_4413643_0 ATPase (AAA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 378.0
HKD3_k127_4413643_1 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000000000000000000000000000000000005939 195.0
HKD3_k127_4413643_2 Protein of unknown function (DUF3300) - - - 0.00000000000000000005997 92.0
HKD3_k127_4413643_3 membrane - - - 0.0000002432 63.0
HKD3_k127_4439051_0 Transmembrane secretion effector - - - 1.747e-246 784.0
HKD3_k127_4439051_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 616.0
HKD3_k127_4439051_10 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 304.0
HKD3_k127_4439051_11 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001164 244.0
HKD3_k127_4439051_12 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000001465 210.0
HKD3_k127_4439051_13 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000003474 190.0
HKD3_k127_4439051_2 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 591.0
HKD3_k127_4439051_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 580.0
HKD3_k127_4439051_4 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 550.0
HKD3_k127_4439051_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 476.0
HKD3_k127_4439051_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 403.0
HKD3_k127_4439051_7 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 395.0
HKD3_k127_4439051_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 391.0
HKD3_k127_4439051_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 381.0
HKD3_k127_4477330_0 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 541.0
HKD3_k127_4477330_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 467.0
HKD3_k127_4477330_2 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K15022 - 1.17.1.10 0.000000000000000000000006727 101.0
HKD3_k127_450890_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.86e-281 874.0
HKD3_k127_450890_1 4Fe-4S dicluster domain - - - 1.709e-219 717.0
HKD3_k127_450890_2 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000000000000006719 145.0
HKD3_k127_450890_3 Nitrate reductase delta subunit - - - 0.000000000000000000000000000000009509 148.0
HKD3_k127_450890_4 Protein of unknown function (DUF3306) - - - 0.0000000000000000000006361 109.0
HKD3_k127_450890_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000006406 59.0
HKD3_k127_450890_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000009119 59.0
HKD3_k127_4510269_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1028.0
HKD3_k127_4510269_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.169e-320 989.0
HKD3_k127_4510269_10 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 347.0
HKD3_k127_4510269_11 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 333.0
HKD3_k127_4510269_12 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 338.0
HKD3_k127_4510269_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 322.0
HKD3_k127_4510269_14 Sigma E regulatory protein, MucB RseB K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001146 252.0
HKD3_k127_4510269_15 Ribonuclease III family K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000002208 245.0
HKD3_k127_4510269_16 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000001018 235.0
HKD3_k127_4510269_17 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000006963 133.0
HKD3_k127_4510269_18 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.000000000000000008804 96.0
HKD3_k127_4510269_19 COG0526 Thiol-disulfide isomerase and thioredoxins K00384 - 1.8.1.9 0.00000000000000001129 87.0
HKD3_k127_4510269_2 PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A K01908 - 6.2.1.17 1.36e-317 1003.0
HKD3_k127_4510269_20 Domain of unknown function (DUF4845) - - - 0.0000000000001242 78.0
HKD3_k127_4510269_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.21e-229 722.0
HKD3_k127_4510269_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 523.0
HKD3_k127_4510269_5 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 464.0
HKD3_k127_4510269_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 420.0
HKD3_k127_4510269_7 AFG1-like ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 416.0
HKD3_k127_4510269_8 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 372.0
HKD3_k127_4510269_9 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 351.0
HKD3_k127_4601980_0 AsnC-type helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000005064 205.0
HKD3_k127_4601980_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - 0.00000000000000000000000000000000000000000000000000003734 199.0
HKD3_k127_4601980_2 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.0000000000000000000000000000000000000000004687 160.0
HKD3_k127_469236_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.506e-241 768.0
HKD3_k127_469236_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 567.0
HKD3_k127_469236_10 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000002047 159.0
HKD3_k127_469236_11 Protein of unknown function (DUF3306) - - - 0.00000000000000000000004621 112.0
HKD3_k127_469236_12 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000001147 90.0
HKD3_k127_469236_2 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 561.0
HKD3_k127_469236_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 518.0
HKD3_k127_469236_4 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 484.0
HKD3_k127_469236_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 488.0
HKD3_k127_469236_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 386.0
HKD3_k127_469236_7 Lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 390.0
HKD3_k127_469236_8 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000001801 265.0
HKD3_k127_469236_9 Protein of unknown function (DUF3305) - - - 0.000000000000000000000000000000000001727 143.0
HKD3_k127_4851484_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 552.0
HKD3_k127_4851484_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006277 281.0
HKD3_k127_4851484_2 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007805 280.0
HKD3_k127_4851484_3 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000008727 183.0
HKD3_k127_4851484_4 Pfam Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000005611 158.0
HKD3_k127_4851484_5 TonB C terminal K03646 - - 0.000000000000000000000000000000000000158 156.0
HKD3_k127_4851484_6 HAD-hyrolase-like - - - 0.000000000000000000000000000000001764 135.0
HKD3_k127_4851484_7 Tol-pal system-associated acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000001677 137.0
HKD3_k127_4851484_8 - - - - 0.000000000000003649 87.0
HKD3_k127_4862152_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 582.0
HKD3_k127_4862152_1 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 555.0
HKD3_k127_4862152_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 333.0
HKD3_k127_4862152_3 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 282.0
HKD3_k127_4862152_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000133 285.0
HKD3_k127_4862152_5 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000642 237.0
HKD3_k127_4862152_6 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000003568 140.0
HKD3_k127_4862152_7 - - - - 0.00000000000000000000000000000002436 128.0
HKD3_k127_4862152_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000004602 116.0
HKD3_k127_4862152_9 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000001211 98.0
HKD3_k127_4864382_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.281e-198 631.0
HKD3_k127_4864382_1 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 478.0
HKD3_k127_4864382_2 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 477.0
HKD3_k127_4864382_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 417.0
HKD3_k127_4864382_4 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000954 272.0
HKD3_k127_4870994_0 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 571.0
HKD3_k127_4870994_1 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 445.0
HKD3_k127_4870994_2 Protein of unknown function (DUF3750) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001262 248.0
HKD3_k127_4870994_3 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000000000000000163 163.0
HKD3_k127_4870994_4 - - - - 0.000000000000000000000000000000365 132.0
HKD3_k127_4870994_5 cyclic nucleotide binding K00384,K10914 - 1.8.1.9 0.000000000000000000000000000002426 126.0
HKD3_k127_4872723_0 COG0841 Cation multidrug efflux pump K18902,K19594 - - 1.119e-217 687.0
HKD3_k127_4872723_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298,K19586 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002623 251.0
HKD3_k127_4909116_0 PFAM NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.0 1142.0
HKD3_k127_4909116_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 412.0
HKD3_k127_4909116_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 303.0
HKD3_k127_4909116_3 PFAM regulatory protein, MarR - - - 0.0000000000000000000000000000000000000000000000000002367 201.0
HKD3_k127_4966218_0 enoyl-CoA hydratase K15513 - 4.1.2.44 7.879e-261 816.0
HKD3_k127_4966218_1 type II secretion system protein E K02454,K02504,K02652,K12276 - - 8.825e-260 813.0
HKD3_k127_4966218_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 439.0
HKD3_k127_4966218_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 394.0
HKD3_k127_4966218_12 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 372.0
HKD3_k127_4966218_13 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 350.0
HKD3_k127_4966218_14 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 344.0
HKD3_k127_4966218_15 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 331.0
HKD3_k127_4966218_16 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 327.0
HKD3_k127_4966218_17 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 305.0
HKD3_k127_4966218_18 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 298.0
HKD3_k127_4966218_19 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000007439 261.0
HKD3_k127_4966218_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 3.716e-255 796.0
HKD3_k127_4966218_20 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000833 260.0
HKD3_k127_4966218_21 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000003081 231.0
HKD3_k127_4966218_22 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000458 235.0
HKD3_k127_4966218_23 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000000000000000000000000000000034 200.0
HKD3_k127_4966218_24 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000001754 205.0
HKD3_k127_4966218_25 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000002089 207.0
HKD3_k127_4966218_26 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.00000000000000000000000000000000000000000000000000005152 193.0
HKD3_k127_4966218_27 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000005636 197.0
HKD3_k127_4966218_28 thioesterase K01075 - 3.1.2.23 0.0000000000000000000000000000000000000003996 164.0
HKD3_k127_4966218_29 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000008462 153.0
HKD3_k127_4966218_3 AAA ATPase domain - - - 2.849e-244 800.0
HKD3_k127_4966218_30 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000000924 159.0
HKD3_k127_4966218_31 PFAM transport-associated - - - 0.000000000000000000000000000000000000434 150.0
HKD3_k127_4966218_32 Rubrerythrin - - - 0.0000000000000000000000000000003535 135.0
HKD3_k127_4966218_33 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000005068 126.0
HKD3_k127_4966218_34 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000002173 117.0
HKD3_k127_4966218_35 RDD family - - - 0.000000000001562 81.0
HKD3_k127_4966218_36 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.00006203 56.0
HKD3_k127_4966218_4 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 2.452e-242 759.0
HKD3_k127_4966218_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 9.032e-210 660.0
HKD3_k127_4966218_6 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 609.0
HKD3_k127_4966218_7 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 567.0
HKD3_k127_4966218_8 type II secretion system protein K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 514.0
HKD3_k127_4966218_9 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 449.0
HKD3_k127_5030070_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 618.0
HKD3_k127_5030070_1 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 612.0
HKD3_k127_5030070_2 e3 binding domain K09699 - 2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 484.0
HKD3_k127_5030070_3 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 461.0
HKD3_k127_5030070_4 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 426.0
HKD3_k127_5030070_5 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 395.0
HKD3_k127_5030070_6 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 361.0
HKD3_k127_5030070_7 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.0000000000000000000005527 105.0
HKD3_k127_5030070_8 Spore Coat Protein U domain - - - 0.0000000000002092 78.0
HKD3_k127_5030070_9 Spore Coat Protein U domain - - - 0.0001904 52.0
HKD3_k127_5076155_0 Tripartite tricarboxylate transporter TctA family K07793 - - 4.076e-244 761.0
HKD3_k127_5076155_1 Belongs to the mandelate racemase muconate lactonizing enzyme family K01706 - 4.2.1.40 8.296e-238 741.0
HKD3_k127_5076155_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 470.0
HKD3_k127_5076155_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 452.0
HKD3_k127_5076155_4 Belongs to the HpcH HpaI aldolase family K01630 - 4.1.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001422 281.0
HKD3_k127_5076155_5 High-affinity nickel-transport protein K07241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003261 282.0
HKD3_k127_5076155_6 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000009403 170.0
HKD3_k127_5076155_7 Tricorn protease C1 domain K08676 - - 0.0000004498 53.0
HKD3_k127_5089958_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 486.0
HKD3_k127_5089958_1 ATPase (AAA K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 380.0
HKD3_k127_5089958_2 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 325.0
HKD3_k127_5089958_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000008577 139.0
HKD3_k127_5089958_4 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000000451 92.0
HKD3_k127_5095856_0 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 6.406e-244 760.0
HKD3_k127_5095856_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.406e-201 669.0
HKD3_k127_5146239_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1150.0
HKD3_k127_5146239_1 DNA polymerase III K02342 - 2.7.7.7 1.67e-237 754.0
HKD3_k127_5146239_10 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 289.0
HKD3_k127_5146239_11 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000001068 222.0
HKD3_k127_5146239_12 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000001382 181.0
HKD3_k127_5146239_13 - - - - 0.000000000000008132 77.0
HKD3_k127_5146239_14 MORN repeat protein - - - 0.000004141 57.0
HKD3_k127_5146239_2 ABC transporter substrate-binding protein K02035,K13889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 618.0
HKD3_k127_5146239_3 Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 609.0
HKD3_k127_5146239_4 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 542.0
HKD3_k127_5146239_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009764 482.0
HKD3_k127_5146239_6 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 458.0
HKD3_k127_5146239_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 451.0
HKD3_k127_5146239_8 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 386.0
HKD3_k127_5146239_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 379.0
HKD3_k127_5150871_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1512.0
HKD3_k127_5150871_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.87e-294 917.0
HKD3_k127_5150871_10 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 308.0
HKD3_k127_5150871_11 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008367 276.0
HKD3_k127_5150871_12 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 259.0
HKD3_k127_5150871_13 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001312 246.0
HKD3_k127_5150871_14 peptidase inhibitor activity K07260 - 3.4.17.14 0.0000000000000000000000000000000000000000000000000000000000001592 239.0
HKD3_k127_5150871_15 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000001679 210.0
HKD3_k127_5150871_16 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000008682 192.0
HKD3_k127_5150871_17 4Fe-4S dicluster domain K00196,K05796 - - 0.0000000000000000000000000000000000000000000000000116 195.0
HKD3_k127_5150871_18 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000001184 171.0
HKD3_k127_5150871_19 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000000001141 169.0
HKD3_k127_5150871_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 3.377e-258 810.0
HKD3_k127_5150871_20 - - - - 0.00000000000000000000000000000000001456 152.0
HKD3_k127_5150871_21 Copper resistance protein D - - - 0.000000000000000000000000000001764 126.0
HKD3_k127_5150871_22 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000009766 86.0
HKD3_k127_5150871_23 Subtilase family - - - 0.0000000000000004413 93.0
HKD3_k127_5150871_25 OmpA family - - - 0.0000004302 60.0
HKD3_k127_5150871_26 PFAM thiamineS protein - - - 0.0000007005 54.0
HKD3_k127_5150871_3 OPT oligopeptide transporter protein - - - 4.159e-248 796.0
HKD3_k127_5150871_4 Transport of potassium into the cell K03549 - - 4.658e-231 730.0
HKD3_k127_5150871_5 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 623.0
HKD3_k127_5150871_6 PFAM polysaccharide deacetylase K01452 - 3.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 481.0
HKD3_k127_5150871_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 499.0
HKD3_k127_5150871_8 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 462.0
HKD3_k127_5150871_9 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 404.0
HKD3_k127_5222667_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1287.0
HKD3_k127_5222667_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000005074 194.0
HKD3_k127_5227247_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 339.0
HKD3_k127_5227247_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 318.0
HKD3_k127_5227247_2 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002025 279.0
HKD3_k127_5227247_3 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000008089 191.0
HKD3_k127_5227247_4 Autotransporter beta-domain K12686 - - 0.0000000000000000000000000000000001304 141.0
HKD3_k127_5227247_5 Sporulation related domain - - - 0.0000000000000000000000008342 115.0
HKD3_k127_5325994_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 367.0
HKD3_k127_5325994_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 362.0
HKD3_k127_5325994_2 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 302.0
HKD3_k127_5325994_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000002003 181.0
HKD3_k127_5325994_4 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.00000001007 62.0
HKD3_k127_5346455_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 3.189e-299 937.0
HKD3_k127_5346455_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 529.0
HKD3_k127_5346455_10 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000001449 233.0
HKD3_k127_5346455_11 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000008451 203.0
HKD3_k127_5346455_12 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000000000000000000000000003424 179.0
HKD3_k127_5346455_13 - - - - 0.0000000000000000000000000000005907 128.0
HKD3_k127_5346455_14 Transcriptional regulator K04033 - - 0.000000000000000000002292 105.0
HKD3_k127_5346455_15 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000000000002178 92.0
HKD3_k127_5346455_16 Transcriptional regulatory protein, C terminal - - - 0.0002423 53.0
HKD3_k127_5346455_2 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 532.0
HKD3_k127_5346455_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 375.0
HKD3_k127_5346455_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 352.0
HKD3_k127_5346455_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 341.0
HKD3_k127_5346455_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 315.0
HKD3_k127_5346455_7 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 307.0
HKD3_k127_5346455_8 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 297.0
HKD3_k127_5346455_9 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005204 246.0
HKD3_k127_5404345_0 arylsulfatase A K01130 - 3.1.6.1 2.17e-261 817.0
HKD3_k127_5404345_1 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 1.962e-228 728.0
HKD3_k127_5404345_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 323.0
HKD3_k127_5404345_11 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003788 259.0
HKD3_k127_5404345_12 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000005749 217.0
HKD3_k127_5404345_13 response regulator - - - 0.0000000000000000000000000000000000000000000004791 176.0
HKD3_k127_5404345_14 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000524 173.0
HKD3_k127_5404345_15 Small multidrug resistance - - - 0.0000000000000000000000000000000000003129 149.0
HKD3_k127_5404345_16 Bacterial transcriptional activator domain - - - 0.0000000000000009545 91.0
HKD3_k127_5404345_2 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 572.0
HKD3_k127_5404345_3 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 465.0
HKD3_k127_5404345_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 462.0
HKD3_k127_5404345_5 Pfam Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 426.0
HKD3_k127_5404345_6 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 420.0
HKD3_k127_5404345_7 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 417.0
HKD3_k127_5404345_8 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 388.0
HKD3_k127_5404345_9 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 400.0
HKD3_k127_5520725_0 Belongs to the IlvD Edd family - - - 5.423e-279 866.0
HKD3_k127_5520725_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 2.253e-265 835.0
HKD3_k127_5520725_10 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 428.0
HKD3_k127_5520725_11 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 430.0
HKD3_k127_5520725_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 407.0
HKD3_k127_5520725_13 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 426.0
HKD3_k127_5520725_14 THUMP K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 409.0
HKD3_k127_5520725_15 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 376.0
HKD3_k127_5520725_16 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 329.0
HKD3_k127_5520725_17 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 349.0
HKD3_k127_5520725_18 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 314.0
HKD3_k127_5520725_19 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 314.0
HKD3_k127_5520725_2 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.062e-263 819.0
HKD3_k127_5520725_20 KR domain K10780 - 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 305.0
HKD3_k127_5520725_21 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 317.0
HKD3_k127_5520725_22 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 287.0
HKD3_k127_5520725_23 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 298.0
HKD3_k127_5520725_24 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001695 272.0
HKD3_k127_5520725_25 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000399 252.0
HKD3_k127_5520725_26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000001527 258.0
HKD3_k127_5520725_27 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000003343 246.0
HKD3_k127_5520725_28 Serine aminopeptidase, S33 K07018 - - 0.000000000000000000000000000000000000000000000000000000000000002779 229.0
HKD3_k127_5520725_29 lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000504 242.0
HKD3_k127_5520725_3 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain, Biotin carboxylase C-terminal domain, Carbamoyl-phosphate synthase L chain, N-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 3.844e-247 769.0
HKD3_k127_5520725_30 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000154 212.0
HKD3_k127_5520725_31 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000001062 224.0
HKD3_k127_5520725_32 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000002806 192.0
HKD3_k127_5520725_33 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.0000000000000000000000000000000000000000003077 173.0
HKD3_k127_5520725_34 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000000000000000000000000000000000004424 168.0
HKD3_k127_5520725_35 Ferredoxin - - - 0.0000000000000000000000000000000000000000005575 161.0
HKD3_k127_5520725_36 Phosphopantetheine attachment site - - - 0.0000000000000000000000000000000000000009568 151.0
HKD3_k127_5520725_37 Thioredoxin-like - - - 0.000000000000000000000000000000000000005592 151.0
HKD3_k127_5520725_38 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000000001026 151.0
HKD3_k127_5520725_39 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000001204 134.0
HKD3_k127_5520725_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 3.085e-208 658.0
HKD3_k127_5520725_40 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000001653 136.0
HKD3_k127_5520725_41 of cations and cationic drugs K03297 - - 0.00000000000000000000000000000008357 127.0
HKD3_k127_5520725_42 protein involved in tolerance to divalent cations K03926 - - 0.000000000000000000000000000000638 124.0
HKD3_k127_5520725_43 FabA-like domain - - - 0.0000000000000000000003416 106.0
HKD3_k127_5520725_44 Transcriptional regulator - - - 0.000000000000000006994 94.0
HKD3_k127_5520725_45 Domain of unknown function (DUF4124) - - - 0.0000000000008975 77.0
HKD3_k127_5520725_46 PFAM FxsA cytoplasmic membrane protein K07113 - - 0.00000000002168 71.0
HKD3_k127_5520725_47 - - - - 0.00000002316 64.0
HKD3_k127_5520725_49 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0003006 54.0
HKD3_k127_5520725_5 Organic solvent tolerance protein K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 581.0
HKD3_k127_5520725_6 PFAM membrane bound O-acyl transferase MBOAT K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 478.0
HKD3_k127_5520725_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 455.0
HKD3_k127_5520725_8 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 443.0
HKD3_k127_5520725_9 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 432.0
HKD3_k127_5568266_0 PFAM Acyl-CoA dehydrogenase K00252 - 1.3.8.6 2.352e-209 657.0
HKD3_k127_5568266_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 567.0
HKD3_k127_5568266_10 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000001333 167.0
HKD3_k127_5568266_11 transcriptional regulator - - - 0.0000000000000000000000000000000000002984 149.0
HKD3_k127_5568266_12 FR47-like protein - - - 0.000000000000000000000000000000000005886 156.0
HKD3_k127_5568266_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 505.0
HKD3_k127_5568266_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 343.0
HKD3_k127_5568266_4 fumarylacetoacetate hydrolase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000103 271.0
HKD3_k127_5568266_5 Maleylacetoacetate isomerase K01801 - 5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000007306 279.0
HKD3_k127_5568266_6 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000004198 250.0
HKD3_k127_5568266_7 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000001547 173.0
HKD3_k127_5568266_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000002285 175.0
HKD3_k127_5568266_9 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000002981 168.0
HKD3_k127_5646302_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 5.29e-238 742.0
HKD3_k127_5646302_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000001258 78.0
HKD3_k127_5712720_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 507.0
HKD3_k127_5712720_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 480.0
HKD3_k127_5712720_2 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 479.0
HKD3_k127_5712720_3 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 369.0
HKD3_k127_5712720_4 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 357.0
HKD3_k127_5712720_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 356.0
HKD3_k127_5712720_6 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 298.0
HKD3_k127_5725343_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 573.0
HKD3_k127_5725343_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 351.0
HKD3_k127_5725343_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 319.0
HKD3_k127_5725343_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000002679 272.0
HKD3_k127_5725343_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000006433 179.0
HKD3_k127_5725343_5 Belongs to the BolA IbaG family - - - 0.00000000000000000000000002524 121.0
HKD3_k127_5902411_0 Histidine kinase-like ATPases - - - 0.0 1185.0
HKD3_k127_5902411_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1066.0
HKD3_k127_5902411_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 430.0
HKD3_k127_5902411_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 366.0
HKD3_k127_5902411_4 Histidine kinase K20976 - - 0.0000000000000002545 83.0
HKD3_k127_595421_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1201.0
HKD3_k127_595421_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.0000000000004547 74.0
HKD3_k127_600623_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 6.423e-202 638.0
HKD3_k127_600623_1 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 602.0
HKD3_k127_600623_2 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 551.0
HKD3_k127_600623_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 398.0
HKD3_k127_600623_4 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 392.0
HKD3_k127_600623_5 CHAD - - - 0.000000000000000000000000000000000000000000000000000000000001748 230.0
HKD3_k127_600623_6 PFAM PsiF repeat protein - - - 0.0000000000000000004135 93.0
HKD3_k127_6046992_0 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 396.0
HKD3_k127_6046992_1 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000001798 211.0
HKD3_k127_6109831_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 4.565e-279 883.0
HKD3_k127_6109831_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 1.93e-223 736.0
HKD3_k127_6109831_10 DnaJ-class molecular chaperone with C-terminal Zn finger domain K03686 - - 0.00000002714 61.0
HKD3_k127_6109831_2 Zinc finger found in FPG and IleRS K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 467.0
HKD3_k127_6109831_3 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 418.0
HKD3_k127_6109831_4 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 397.0
HKD3_k127_6109831_5 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 336.0
HKD3_k127_6109831_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 330.0
HKD3_k127_6109831_7 Belongs to the peptidase S24 family K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000004904 260.0
HKD3_k127_6109831_8 OHCU decarboxylase K13485 - 4.1.1.97 0.00000000000000000000000000000000000000000000000001663 184.0
HKD3_k127_6109831_9 Domain of unknown function (DUF1330) - - - 0.000000000000000001844 87.0
HKD3_k127_6119557_0 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 529.0
HKD3_k127_6119557_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 303.0
HKD3_k127_6129502_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.367e-294 923.0
HKD3_k127_6129502_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 9.982e-285 887.0
HKD3_k127_6129502_10 TRAP transporter solute receptor TAXI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 329.0
HKD3_k127_6129502_11 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 291.0
HKD3_k127_6129502_12 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004909 242.0
HKD3_k127_6129502_13 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000001717 222.0
HKD3_k127_6129502_14 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000001814 211.0
HKD3_k127_6129502_15 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000004394 194.0
HKD3_k127_6129502_16 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000001944 201.0
HKD3_k127_6129502_17 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000008436 188.0
HKD3_k127_6129502_18 redox protein, regulator of disulfide bond formation K07397 - - 0.000000000000000000000000000000000000000000000001462 178.0
HKD3_k127_6129502_19 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000008905 185.0
HKD3_k127_6129502_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 1.547e-195 612.0
HKD3_k127_6129502_20 oxidation protein K17227 - - 0.00000000000000000000000000000000000000000002808 163.0
HKD3_k127_6129502_21 intradiol ring-cleavage dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000003896 174.0
HKD3_k127_6129502_22 Thioredoxin-like - - - 0.00000000000000000000000000000000000000001205 160.0
HKD3_k127_6129502_23 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000007689 154.0
HKD3_k127_6129502_24 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000339 152.0
HKD3_k127_6129502_25 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000004178 136.0
HKD3_k127_6129502_26 acetyltransferase K03825 - - 0.000000000000000000000000000009057 136.0
HKD3_k127_6129502_27 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797 - 2.5.1.16 0.0000000000000000000000009195 111.0
HKD3_k127_6129502_28 - - - - 0.0000000000000000000000009975 120.0
HKD3_k127_6129502_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 578.0
HKD3_k127_6129502_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 492.0
HKD3_k127_6129502_5 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 393.0
HKD3_k127_6129502_6 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 383.0
HKD3_k127_6129502_7 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 377.0
HKD3_k127_6129502_8 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 353.0
HKD3_k127_6129502_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 326.0
HKD3_k127_6150145_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.11e-213 681.0
HKD3_k127_6150145_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 573.0
HKD3_k127_6150145_2 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 380.0
HKD3_k127_6150145_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 325.0
HKD3_k127_6150145_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 325.0
HKD3_k127_6150145_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004427 250.0
HKD3_k127_6150145_6 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004539 238.0
HKD3_k127_6150145_7 Tripartite ATP-independent periplasmic transporters, DctQ component K11689,K21394 - - 0.0000000000000000000000000000000000000000000000000000000000001153 220.0
HKD3_k127_6150145_8 Cell division protein ZapA K09888 - - 0.0000000000000000001069 97.0
HKD3_k127_6150145_9 - - - - 0.00000415 51.0
HKD3_k127_6170652_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1126.0
HKD3_k127_6170652_1 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002876 248.0
HKD3_k127_6170652_2 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.000000000000000000000000000000000000000000000000002664 186.0
HKD3_k127_6170652_3 transcriptional regulator, XRE family - - - 0.000000000000000000000000000000000000000008821 157.0
HKD3_k127_6170652_4 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K19168 - - 0.00000005927 61.0
HKD3_k127_6170652_5 - - - - 0.0000001453 53.0
HKD3_k127_6180481_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1304.0
HKD3_k127_6180481_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 614.0
HKD3_k127_6180481_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 526.0
HKD3_k127_6180481_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 402.0
HKD3_k127_6180481_4 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 302.0
HKD3_k127_6180481_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000003097 173.0
HKD3_k127_6180481_6 Cell wall formation K01921 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 0.00000000000000000000000001846 110.0
HKD3_k127_6180481_7 Protein of unknown function (DUF721) - - - 0.0000005342 57.0
HKD3_k127_6194284_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1512.0
HKD3_k127_6194284_1 PFAM peptidase S10 serine carboxypeptidase - - - 5.196e-210 661.0
HKD3_k127_6194284_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 502.0
HKD3_k127_6194284_3 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 454.0
HKD3_k127_6194284_4 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 299.0
HKD3_k127_6194284_5 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000008367 183.0
HKD3_k127_6194284_6 Belongs to the DnaA family K10763 - - 0.000000000000000000000000000000000000000000000007693 181.0
HKD3_k127_6194284_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000005159 187.0
HKD3_k127_6194284_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000007988 126.0
HKD3_k127_6215227_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01706 - 4.2.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 610.0
HKD3_k127_6215227_1 PFAM fumarylacetoacetate (FAA) hydrolase K16856 - 4.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 406.0
HKD3_k127_6215227_2 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 422.0
HKD3_k127_6215227_3 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 326.0
HKD3_k127_6215227_4 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002159 246.0
HKD3_k127_6215227_5 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000005843 231.0
HKD3_k127_6215227_6 Prolyl oligopeptidase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000302 215.0
HKD3_k127_6215227_7 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000000001604 218.0
HKD3_k127_6218379_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 1.493e-313 980.0
HKD3_k127_6218379_1 Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05559 - - 1.423e-287 910.0
HKD3_k127_6218379_10 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 469.0
HKD3_k127_6218379_11 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 393.0
HKD3_k127_6218379_12 HD domain K13815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 376.0
HKD3_k127_6218379_13 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 357.0
HKD3_k127_6218379_14 Proton-conducting membrane transporter K00342,K05561,K05568 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 373.0
HKD3_k127_6218379_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 291.0
HKD3_k127_6218379_16 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000005677 231.0
HKD3_k127_6218379_17 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000000000000002304 230.0
HKD3_k127_6218379_18 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000009983 231.0
HKD3_k127_6218379_19 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000002972 198.0
HKD3_k127_6218379_2 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 9.23e-285 889.0
HKD3_k127_6218379_20 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000009445 184.0
HKD3_k127_6218379_21 PFAM regulatory protein, MerR - - - 0.0000000000000000000000000000000000000000000001921 171.0
HKD3_k127_6218379_22 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000007804 171.0
HKD3_k127_6218379_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000007821 161.0
HKD3_k127_6218379_24 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000000000002953 158.0
HKD3_k127_6218379_25 NADH-ubiquinone oxidoreductase subunit 4L K05560 - - 0.00000000000000000000000002401 128.0
HKD3_k127_6218379_26 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000000007054 107.0
HKD3_k127_6218379_27 PFAM Na H antiporter subunit K05564 - - 0.000000000000000000001404 104.0
HKD3_k127_6218379_28 Multiple resistance and pH regulation protein F K05563 - - 0.000000000000000000007085 99.0
HKD3_k127_6218379_3 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.796e-249 794.0
HKD3_k127_6218379_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.647e-230 728.0
HKD3_k127_6218379_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 6.234e-221 694.0
HKD3_k127_6218379_6 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 610.0
HKD3_k127_6218379_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 590.0
HKD3_k127_6218379_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 539.0
HKD3_k127_6218379_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 509.0
HKD3_k127_6232686_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1265.0
HKD3_k127_6232686_1 Belongs to the ABC transporter superfamily K02031,K02032,K13892 - - 7.008e-284 886.0
HKD3_k127_6232686_10 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 340.0
HKD3_k127_6232686_11 Permease YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 295.0
HKD3_k127_6232686_12 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003875 291.0
HKD3_k127_6232686_13 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000009306 168.0
HKD3_k127_6232686_14 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000000000000007517 146.0
HKD3_k127_6232686_15 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000007997 134.0
HKD3_k127_6232686_2 ABC-type dipeptide transport system, periplasmic K02035,K13889 - - 5.033e-244 762.0
HKD3_k127_6232686_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1.671e-209 662.0
HKD3_k127_6232686_4 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K13890 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 498.0
HKD3_k127_6232686_5 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 497.0
HKD3_k127_6232686_6 PFAM binding-protein-dependent transport systems inner membrane component K13891 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 481.0
HKD3_k127_6232686_7 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 415.0
HKD3_k127_6232686_8 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 384.0
HKD3_k127_6232686_9 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 378.0
HKD3_k127_6263068_0 AMP-binding enzyme C-terminal domain K00666 - - 4.542e-260 812.0
HKD3_k127_6263068_1 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 2.824e-212 679.0
HKD3_k127_6263068_10 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 474.0
HKD3_k127_6263068_11 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 399.0
HKD3_k127_6263068_12 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 360.0
HKD3_k127_6263068_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 351.0
HKD3_k127_6263068_14 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 349.0
HKD3_k127_6263068_15 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 323.0
HKD3_k127_6263068_16 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 306.0
HKD3_k127_6263068_17 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 296.0
HKD3_k127_6263068_18 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000005016 267.0
HKD3_k127_6263068_19 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 270.0
HKD3_k127_6263068_2 Permease family K02824 - - 2.261e-209 662.0
HKD3_k127_6263068_20 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003366 256.0
HKD3_k127_6263068_21 catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000002965 250.0
HKD3_k127_6263068_22 Protein of unknown function, DUF480 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001387 247.0
HKD3_k127_6263068_23 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000005437 231.0
HKD3_k127_6263068_24 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000001397 228.0
HKD3_k127_6263068_25 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000004294 200.0
HKD3_k127_6263068_26 Aspartyl protease - - - 0.00000000000000000000000000000000000000000000000000003122 211.0
HKD3_k127_6263068_27 domain, Protein - - - 0.000000000000000000000000000000000000000000000000001556 186.0
HKD3_k127_6263068_28 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.0000000000000000000000000000000000000000000000005343 184.0
HKD3_k127_6263068_29 peptide chain release factor K15034 - - 0.000000000000000000000000000000000000000000004552 169.0
HKD3_k127_6263068_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 9.25e-207 655.0
HKD3_k127_6263068_30 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000709 184.0
HKD3_k127_6263068_31 Dehydratase K13919 - 4.2.1.28 0.000000000000000000000000000000000000000003979 178.0
HKD3_k127_6263068_32 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000000000003127 162.0
HKD3_k127_6263068_33 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000000000000000002165 152.0
HKD3_k127_6263068_34 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000004907 153.0
HKD3_k127_6263068_35 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000003728 159.0
HKD3_k127_6263068_36 iron ion homeostasis - - - 0.000000000000000000000000000000000000003869 157.0
HKD3_k127_6263068_37 Domain of unknown function DUF123 - - - 0.000000000000000000000000000000007978 130.0
HKD3_k127_6263068_38 NnrU protein - - - 0.000000000000000000000000000002774 130.0
HKD3_k127_6263068_39 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000001537 112.0
HKD3_k127_6263068_4 Dehydratase large subunit K01699,K06120 - 4.2.1.28,4.2.1.30 2.757e-206 668.0
HKD3_k127_6263068_40 Dehydratase small subunit K06122,K13920 - 4.2.1.28,4.2.1.30 0.000000000000000000001327 103.0
HKD3_k127_6263068_41 - - - - 0.0000002852 64.0
HKD3_k127_6263068_42 Protein of unknown function (DUF1499) - - - 0.000005069 52.0
HKD3_k127_6263068_43 Protein of unknown function (DUF3149) - - - 0.0004793 45.0
HKD3_k127_6263068_44 Periplasmic Protein - GO:0003674,GO:0004857,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0016020,GO:0019867,GO:0030234,GO:0030312,GO:0030313,GO:0031975,GO:0043086,GO:0044092,GO:0044462,GO:0044464,GO:0050790,GO:0060241,GO:0065007,GO:0065009,GO:0071944,GO:0098772 - 0.0005907 48.0
HKD3_k127_6263068_5 tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 5.61e-201 635.0
HKD3_k127_6263068_6 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 598.0
HKD3_k127_6263068_7 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 518.0
HKD3_k127_6263068_8 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 479.0
HKD3_k127_6263068_9 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 450.0
HKD3_k127_6332221_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.637e-307 967.0
HKD3_k127_6332221_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.701e-287 899.0
HKD3_k127_6332221_10 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 506.0
HKD3_k127_6332221_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 456.0
HKD3_k127_6332221_12 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 436.0
HKD3_k127_6332221_13 Acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 412.0
HKD3_k127_6332221_14 LysM domain K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 436.0
HKD3_k127_6332221_15 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 370.0
HKD3_k127_6332221_16 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 362.0
HKD3_k127_6332221_17 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 344.0
HKD3_k127_6332221_18 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 322.0
HKD3_k127_6332221_19 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 323.0
HKD3_k127_6332221_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.526e-239 747.0
HKD3_k127_6332221_20 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 311.0
HKD3_k127_6332221_21 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 310.0
HKD3_k127_6332221_22 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005104 285.0
HKD3_k127_6332221_23 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002516 276.0
HKD3_k127_6332221_24 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000002169 256.0
HKD3_k127_6332221_25 arylamine N-acetyltransferase activity K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000004909 270.0
HKD3_k127_6332221_26 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002513 260.0
HKD3_k127_6332221_27 PFAM Glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000000000000000000000000000000000008934 239.0
HKD3_k127_6332221_28 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000001519 232.0
HKD3_k127_6332221_29 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000001806 235.0
HKD3_k127_6332221_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 8.947e-229 717.0
HKD3_k127_6332221_30 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000002914 229.0
HKD3_k127_6332221_31 Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000003855 227.0
HKD3_k127_6332221_32 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000003233 216.0
HKD3_k127_6332221_33 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000008512 207.0
HKD3_k127_6332221_34 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000001641 201.0
HKD3_k127_6332221_35 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000888 169.0
HKD3_k127_6332221_36 Acyl-ACP thioesterase - - - 0.000000000000000000000000000000003076 144.0
HKD3_k127_6332221_37 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000002399 135.0
HKD3_k127_6332221_38 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.0000000000000000000000000000367 124.0
HKD3_k127_6332221_39 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000003161 120.0
HKD3_k127_6332221_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.306e-228 713.0
HKD3_k127_6332221_40 Colicin V production K03558 - - 0.0000000000000000000000000003843 121.0
HKD3_k127_6332221_41 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000008925 111.0
HKD3_k127_6332221_42 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000002939 88.0
HKD3_k127_6332221_43 PFAM Sporulation domain protein K03749 - - 0.00000000000000009546 91.0
HKD3_k127_6332221_44 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000001888 74.0
HKD3_k127_6332221_45 GGDEF domain - - - 0.000000001191 72.0
HKD3_k127_6332221_46 Entericidin EcnA/B family - - - 0.0005888 46.0
HKD3_k127_6332221_5 DNA mismatch repair protein, C-terminal domain K03572 - - 8.029e-195 625.0
HKD3_k127_6332221_6 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 587.0
HKD3_k127_6332221_7 Cys/Met metabolism PLP-dependent enzyme K01739,K01740 - 2.5.1.48,2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 580.0
HKD3_k127_6332221_8 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 567.0
HKD3_k127_6332221_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 561.0
HKD3_k127_6339270_0 PFAM Orn Lys Arg decarboxylase K01584 - 4.1.1.19 0.0 1317.0
HKD3_k127_6339270_1 STAS domain K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 509.0
HKD3_k127_6339270_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 411.0
HKD3_k127_6339270_3 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 288.0
HKD3_k127_6339270_4 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008846 274.0
HKD3_k127_6346062_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1675.0
HKD3_k127_6346062_1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 521.0
HKD3_k127_6346062_2 Bacterial periplasmic substrate-binding proteins K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 454.0
HKD3_k127_6346062_3 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 422.0
HKD3_k127_6346062_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 380.0
HKD3_k127_6346062_5 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 316.0
HKD3_k127_6346062_6 Binding-protein-dependent transport system inner membrane component K10002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 315.0
HKD3_k127_6346062_7 NADPH quinone K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 313.0
HKD3_k127_6346062_8 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001897 287.0
HKD3_k127_6346062_9 Phenylacetic acid degradation protein PaaY K02617,K08279 - - 0.00000000000000000000000000000000000000000000000000000000000000001057 231.0
HKD3_k127_6394010_0 FAD linked oxidase domain protein - - - 4.791e-203 646.0
HKD3_k127_6394010_1 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 454.0
HKD3_k127_6394010_2 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 409.0
HKD3_k127_6394010_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 306.0
HKD3_k127_6447498_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.691e-221 718.0
HKD3_k127_6447498_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 519.0
HKD3_k127_6447498_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000005498 230.0
HKD3_k127_6447498_12 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000003013 183.0
HKD3_k127_6447498_13 Chalcone isomerase-like - - - 0.00000000000000000000000000000000002056 142.0
HKD3_k127_6447498_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000000157 124.0
HKD3_k127_6447498_15 Frataxin-like domain - - - 0.0000000000000000000000001692 109.0
HKD3_k127_6447498_16 - - - - 0.00000000000000007829 94.0
HKD3_k127_6447498_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 445.0
HKD3_k127_6447498_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 421.0
HKD3_k127_6447498_4 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 425.0
HKD3_k127_6447498_5 Glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 364.0
HKD3_k127_6447498_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 312.0
HKD3_k127_6447498_7 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003924 280.0
HKD3_k127_6447498_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001112 259.0
HKD3_k127_6447498_9 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000001694 254.0
HKD3_k127_6537747_0 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 2.457e-225 702.0
HKD3_k127_6537747_1 oxidoreductase K10219 - 1.1.1.312 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 494.0
HKD3_k127_6537747_2 Extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols K04101 - 1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 451.0
HKD3_k127_6537747_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000003044 204.0
HKD3_k127_6537747_4 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.00000000000000000000000000000000000000000000000007794 180.0
HKD3_k127_6537747_5 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.00000000000000000000000000000000000000000002377 178.0
HKD3_k127_6537747_6 Amidohydrolase - - - 0.0000000000003772 68.0
HKD3_k127_6563470_0 Ammonium Transporter Family K03320,K06580 - - 7.195e-218 681.0
HKD3_k127_6563470_1 homoserine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 548.0
HKD3_k127_6563470_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 480.0
HKD3_k127_6563470_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 455.0
HKD3_k127_6563470_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001631 242.0
HKD3_k127_6563470_5 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000008924 233.0
HKD3_k127_6563470_6 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000001352 128.0
HKD3_k127_659668_0 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons - - - 3.246e-223 731.0
HKD3_k127_659668_1 PFAM acyl-CoA dehydrogenase domain protein K00249,K07545 - 1.3.8.3,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 547.0
HKD3_k127_659668_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 331.0
HKD3_k127_659668_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 312.0
HKD3_k127_659668_4 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002355 299.0
HKD3_k127_659668_5 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000102 283.0
HKD3_k127_659668_6 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000003837 228.0
HKD3_k127_659668_7 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000004375 228.0
HKD3_k127_659668_8 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006103 231.0
HKD3_k127_6615596_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 2.729e-248 786.0
HKD3_k127_6615596_1 Sulfatase - - - 1.288e-213 688.0
HKD3_k127_6615596_2 PFAM ABC transporter related K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 374.0
HKD3_k127_6615596_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 342.0
HKD3_k127_6615596_4 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 302.0
HKD3_k127_6615596_5 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 288.0
HKD3_k127_6615596_6 Prokaryotic cytochrome b561 K12262 - - 0.00000000000000000000000000001071 129.0
HKD3_k127_6615596_7 amino acid-binding ACT domain protein K04767 - - 0.000000000000000000000000002618 116.0
HKD3_k127_6615596_8 Acetyltransferase (GNAT) domain - - - 0.00000000000005779 75.0
HKD3_k127_6615596_9 FeoA - - - 0.000001312 62.0
HKD3_k127_6618138_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 531.0
HKD3_k127_6618138_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 516.0
HKD3_k127_6618138_2 ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 441.0
HKD3_k127_6618138_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 376.0
HKD3_k127_6618138_4 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 382.0
HKD3_k127_6618138_5 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002548 245.0
HKD3_k127_6618138_6 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000003118 242.0
HKD3_k127_6618138_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000001753 159.0
HKD3_k127_6618138_8 Belongs to the peptidase S8 family K14645 - - 0.000005612 60.0
HKD3_k127_6618138_9 domain protein - - - 0.000946 44.0
HKD3_k127_6654201_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.238e-251 787.0
HKD3_k127_6654201_1 Phosphoesterase family - - - 3.579e-196 640.0
HKD3_k127_6654201_10 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.0000000000000000000000000000000000000000000000000000004542 202.0
HKD3_k127_6654201_11 COG0346 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000325 153.0
HKD3_k127_6654201_12 Pathogenicity locus - - - 0.000000000000000000000001411 119.0
HKD3_k127_6654201_13 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000001304 59.0
HKD3_k127_6654201_14 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000001784 56.0
HKD3_k127_6654201_2 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 553.0
HKD3_k127_6654201_3 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 501.0
HKD3_k127_6654201_4 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 415.0
HKD3_k127_6654201_5 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 374.0
HKD3_k127_6654201_6 DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 313.0
HKD3_k127_6654201_7 Damage-inducible protein DinB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004736 262.0
HKD3_k127_6654201_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000005305 247.0
HKD3_k127_6654201_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.000000000000000000000000000000000000000000000000000000000217 212.0
HKD3_k127_6702695_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2e-323 1003.0
HKD3_k127_6702695_1 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.893e-226 711.0
HKD3_k127_6702695_10 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 374.0
HKD3_k127_6702695_11 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 366.0
HKD3_k127_6702695_12 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 359.0
HKD3_k127_6702695_13 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 331.0
HKD3_k127_6702695_14 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 321.0
HKD3_k127_6702695_15 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 312.0
HKD3_k127_6702695_16 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 293.0
HKD3_k127_6702695_17 Sulfate permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003201 292.0
HKD3_k127_6702695_18 Carbohydrate ABC transporter membrane protein 1, CUT1 family K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002264 258.0
HKD3_k127_6702695_19 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002797 271.0
HKD3_k127_6702695_2 Metallopeptidase family M24 - - - 1.664e-208 659.0
HKD3_k127_6702695_20 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006882 264.0
HKD3_k127_6702695_21 SMART cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000000000000000005379 206.0
HKD3_k127_6702695_22 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000008429 192.0
HKD3_k127_6702695_24 YjbR - - - 0.0000000000000000000000001348 111.0
HKD3_k127_6702695_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 6.124e-196 620.0
HKD3_k127_6702695_4 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 565.0
HKD3_k127_6702695_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 531.0
HKD3_k127_6702695_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 471.0
HKD3_k127_6702695_7 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 449.0
HKD3_k127_6702695_8 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 430.0
HKD3_k127_6702695_9 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 421.0
HKD3_k127_6870137_0 Protein of unknown function (DUF3141) - - - 4.131e-263 832.0
HKD3_k127_6870137_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 301.0
HKD3_k127_6870137_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000001355 180.0
HKD3_k127_6918578_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 7.358e-281 883.0
HKD3_k127_6918578_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 389.0
HKD3_k127_6918578_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 339.0
HKD3_k127_6918578_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 336.0
HKD3_k127_6918578_4 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003913 263.0
HKD3_k127_6918578_5 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000181 229.0
HKD3_k127_6918578_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000003766 246.0
HKD3_k127_6918578_7 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000000000000000000001444 200.0
HKD3_k127_6918578_8 SAF K16845 - 4.4.1.24 0.000000000000000000000000000000000000003335 148.0
HKD3_k127_6918578_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000008919 135.0
HKD3_k127_6952631_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.664e-266 848.0
HKD3_k127_6952631_1 Protein of unknown function - - - 1.442e-257 858.0
HKD3_k127_6952631_10 abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 319.0
HKD3_k127_6952631_11 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004382 278.0
HKD3_k127_6952631_12 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000000000000000000000002003 198.0
HKD3_k127_6952631_13 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000006352 192.0
HKD3_k127_6952631_14 Small MutS-related domain - - - 0.0000000000000000000000000000000000000000009744 166.0
HKD3_k127_6952631_15 SnoaL-like domain - - - 0.0000000000000000000000000000003953 134.0
HKD3_k127_6952631_16 protein conserved in bacteria - - - 0.0000000000000008714 89.0
HKD3_k127_6952631_17 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000002069 66.0
HKD3_k127_6952631_2 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 2.018e-231 732.0
HKD3_k127_6952631_3 TldD PmbA family protein K03568 - - 9.052e-217 695.0
HKD3_k127_6952631_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.666e-206 659.0
HKD3_k127_6952631_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 489.0
HKD3_k127_6952631_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 452.0
HKD3_k127_6952631_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 403.0
HKD3_k127_6952631_8 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 361.0
HKD3_k127_6952631_9 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 340.0
HKD3_k127_722911_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 8.24e-269 846.0
HKD3_k127_722911_1 Belongs to the glutaminase family K01425 - 3.5.1.2 8.178e-226 715.0
HKD3_k127_722911_10 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009545 264.0
HKD3_k127_722911_11 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000004148 205.0
HKD3_k127_722911_12 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000003246 187.0
HKD3_k127_722911_13 shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000000000001812 158.0
HKD3_k127_722911_14 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000004835 141.0
HKD3_k127_722911_15 Glu-tRNAGln amidotransferase C subunit - - - 0.0000000000000000000000000000007927 125.0
HKD3_k127_722911_16 PFAM HNH endonuclease K07451 - - 0.0000000000000000000005898 104.0
HKD3_k127_722911_17 - - - - 0.00000001162 60.0
HKD3_k127_722911_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 9.016e-213 676.0
HKD3_k127_722911_3 Rod shape-determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 612.0
HKD3_k127_722911_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 507.0
HKD3_k127_722911_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 471.0
HKD3_k127_722911_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 458.0
HKD3_k127_722911_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 439.0
HKD3_k127_722911_8 a g-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 405.0
HKD3_k127_722911_9 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 305.0
HKD3_k127_7252994_0 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 590.0
HKD3_k127_7252994_1 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 409.0
HKD3_k127_7252994_2 binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 371.0
HKD3_k127_7252994_3 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 334.0
HKD3_k127_7252994_4 Peptidase C13 family - - - 0.000000000000000000000000000000000000000003536 172.0
HKD3_k127_7252994_5 Phage integrase family - - - 0.000000000000000000000000000000000000004639 146.0
HKD3_k127_7252994_6 - - - - 0.000000001341 66.0
HKD3_k127_7262036_0 Belongs to the glycosyl hydrolase 31 family K01811 GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0016787,GO:0016798,GO:0042802,GO:0080176 3.2.1.177 9.813e-207 671.0
HKD3_k127_7262036_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 338.0
HKD3_k127_7262036_2 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 320.0
HKD3_k127_7262036_3 Belongs to the HpcH HpaI aldolase family K01630 - 4.1.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 318.0
HKD3_k127_7262036_4 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 329.0
HKD3_k127_7262036_5 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.00000000000000000000000000000000006819 134.0
HKD3_k127_7262036_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.000000000003121 71.0
HKD3_k127_7271973_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 3.764e-197 625.0
HKD3_k127_7271973_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 6.397e-197 621.0
HKD3_k127_7271973_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 443.0
HKD3_k127_7271973_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 428.0
HKD3_k127_7271973_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 379.0
HKD3_k127_7271973_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 343.0
HKD3_k127_7271973_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000000403 139.0
HKD3_k127_7271973_7 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000003202 111.0
HKD3_k127_7271973_8 Uncharacterized ACR, COG1399 K07040 - - 0.00004389 46.0
HKD3_k127_7293153_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 313.0
HKD3_k127_7293153_1 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000006477 169.0
HKD3_k127_7293153_2 Domain of unknown function (DUF4387) - - - 0.0000000000000000000000000000000000000000005233 163.0
HKD3_k127_7293153_3 Pfam:DUF1446 - - - 0.000000000000000000000000000000008641 127.0
HKD3_k127_7293153_4 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000007144 116.0
HKD3_k127_7310622_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 1.718e-241 762.0
HKD3_k127_7310622_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 1.156e-235 737.0
HKD3_k127_7310622_10 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 330.0
HKD3_k127_7310622_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001858 255.0
HKD3_k127_7310622_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004423 248.0
HKD3_k127_7310622_13 Protein of unknown function (DUF3530) - - - 0.00000000000000000000000000000000000000000000006102 193.0
HKD3_k127_7310622_15 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000001203 131.0
HKD3_k127_7310622_16 sodium ion export across plasma membrane K01573 GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234 4.1.1.3 0.0000000000000000000000000002806 117.0
HKD3_k127_7310622_17 Phage tail sheath protein K06907 - - 0.000000000000000000000411 99.0
HKD3_k127_7310622_18 CoA carboxylase activity K01615,K01965,K02160,K17490 - 2.1.3.1,4.1.1.70,6.4.1.3 0.00000000000000000009241 104.0
HKD3_k127_7310622_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.69e-230 721.0
HKD3_k127_7310622_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 623.0
HKD3_k127_7310622_4 oxaloacetate decarboxylase activity K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 593.0
HKD3_k127_7310622_5 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 531.0
HKD3_k127_7310622_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006417 543.0
HKD3_k127_7310622_7 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 486.0
HKD3_k127_7310622_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 462.0
HKD3_k127_7310622_9 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 386.0
HKD3_k127_7313835_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.557e-275 863.0
HKD3_k127_7313835_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 4.111e-238 745.0
HKD3_k127_7313835_10 cheY-homologous receiver domain K02657 - - 0.000000000000000000000000000000000000000000000000000000000000005227 222.0
HKD3_k127_7313835_11 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000007278 199.0
HKD3_k127_7313835_12 phosphohistidine phosphatase K08296 - - 0.0000000000000000000000000000000000000000000000000000009562 198.0
HKD3_k127_7313835_13 RESPONSE REGULATOR receiver K02658 - - 0.0000000000000000000000000000000000000000000000000003213 188.0
HKD3_k127_7313835_14 Chemotaxis signal transduction protein K02659 - - 0.000000000000000000000000000000000000005442 157.0
HKD3_k127_7313835_15 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000002728 108.0
HKD3_k127_7313835_2 Methyl-accepting chemotaxis protein K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 596.0
HKD3_k127_7313835_3 Histidine kinase K02487,K06596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 508.0
HKD3_k127_7313835_4 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 456.0
HKD3_k127_7313835_5 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 419.0
HKD3_k127_7313835_6 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 325.0
HKD3_k127_7313835_7 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 305.0
HKD3_k127_7313835_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000002653 278.0
HKD3_k127_7313835_9 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000003471 247.0
HKD3_k127_7360733_0 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 6.034e-231 728.0
HKD3_k127_7360733_1 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 6.652e-226 708.0
HKD3_k127_7360733_10 response to heat K03668,K06079,K09914 - - 0.00000177 59.0
HKD3_k127_7360733_2 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 529.0
HKD3_k127_7360733_3 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 366.0
HKD3_k127_7360733_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 353.0
HKD3_k127_7360733_5 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 300.0
HKD3_k127_7360733_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000107 269.0
HKD3_k127_7360733_7 Nitroreductase family - - - 0.000000000000000000000000000000000000000000005102 171.0
HKD3_k127_7360733_8 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000001341 112.0
HKD3_k127_7360733_9 Protein of unknown function (DUF2783) - - - 0.0000000000000000004607 91.0
HKD3_k127_7404373_0 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 334.0
HKD3_k127_7404373_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 341.0
HKD3_k127_7404373_2 Circularly permuted ATP-grasp type 2 - - - 0.00000000000000000000000000000000000000000000000000000000003443 206.0
HKD3_k127_7404373_3 Transglutaminase-like superfamily - - - 0.0001682 55.0
HKD3_k127_7419313_0 FAD dependent oxidoreductase - - - 0.0 1098.0
HKD3_k127_7419313_1 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 4.444e-244 762.0
HKD3_k127_7419313_10 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 490.0
HKD3_k127_7419313_11 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 458.0
HKD3_k127_7419313_12 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 437.0
HKD3_k127_7419313_13 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 389.0
HKD3_k127_7419313_14 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 353.0
HKD3_k127_7419313_15 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 298.0
HKD3_k127_7419313_16 binding-protein-dependent transport systems inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 310.0
HKD3_k127_7419313_17 Peptidase C26 K01658,K07010 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001098 289.0
HKD3_k127_7419313_18 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004556 245.0
HKD3_k127_7419313_19 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005113 248.0
HKD3_k127_7419313_2 Na Pi-cotransporter II-related protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 610.0
HKD3_k127_7419313_20 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000004624 255.0
HKD3_k127_7419313_21 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000005675 224.0
HKD3_k127_7419313_22 Domain of unknown function (DUF4743) - - - 0.000000000000000000000000000000000000000000000000000000000009543 217.0
HKD3_k127_7419313_23 TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.000000000000000000000000000000000000000000000009056 180.0
HKD3_k127_7419313_3 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 609.0
HKD3_k127_7419313_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 582.0
HKD3_k127_7419313_5 phosphonoacetate hydrolase K19670 - 3.11.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 579.0
HKD3_k127_7419313_6 binding-protein-dependent transport systems inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 575.0
HKD3_k127_7419313_7 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 557.0
HKD3_k127_7419313_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K00836 - 2.6.1.19,2.6.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 560.0
HKD3_k127_7419313_9 PFAM extracellular solute-binding protein family 1 K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 521.0
HKD3_k127_7442640_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 416.0
HKD3_k127_7442640_1 (Lipo)protein K07287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 332.0
HKD3_k127_7442640_2 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000278 186.0
HKD3_k127_7442640_3 tellurite resistance protein - - - 0.000000000000000000000000000000000003378 141.0
HKD3_k127_7448984_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 3.297e-226 707.0
HKD3_k127_7448984_1 protein involved in propionate catabolism - - - 8.77e-198 630.0
HKD3_k127_7448984_10 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000001513 217.0
HKD3_k127_7448984_11 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000003132 203.0
HKD3_k127_7448984_12 2OG-Fe(II) oxygenase superfamily K07394 - - 0.0000000000000000000000000000000000000000008916 165.0
HKD3_k127_7448984_13 Thioredoxin-like - - - 0.000000000000000000000006873 115.0
HKD3_k127_7448984_14 EamA-like transporter family - - - 0.0001193 46.0
HKD3_k127_7448984_2 L-carnitine dehydratase bile acid-inducible protein F K18289 - 2.8.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 602.0
HKD3_k127_7448984_3 C4-dicarboxylate ABC transporter K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 486.0
HKD3_k127_7448984_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 423.0
HKD3_k127_7448984_5 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 399.0
HKD3_k127_7448984_6 Male sterility protein K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 393.0
HKD3_k127_7448984_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 380.0
HKD3_k127_7448984_8 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 305.0
HKD3_k127_7448984_9 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001639 310.0
HKD3_k127_7497741_0 Malic enzyme K00029 - 1.1.1.40 2.928e-212 668.0
HKD3_k127_7497741_1 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 492.0
HKD3_k127_7497741_2 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 417.0
HKD3_k127_7497741_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 385.0
HKD3_k127_7497741_4 Pyridoxamine 5'-phosphate oxidase like - - - 0.000000000000000000000000001772 119.0
HKD3_k127_7522270_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 573.0
HKD3_k127_7522270_1 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 377.0
HKD3_k127_7522270_2 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003297 231.0
HKD3_k127_7522270_3 COG3278 Cbb3-type cytochrome oxidase, subunit 1 - - - 0.000000000000000000000000000000008912 135.0
HKD3_k127_7522270_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000008955 111.0
HKD3_k127_7522270_5 - - - - 0.00000000000000000004529 102.0
HKD3_k127_7522270_6 - - - - 0.000000000000000001256 92.0
HKD3_k127_753283_0 Transport of potassium into the cell K03549 - - 2.702e-244 769.0
HKD3_k127_753283_1 Dynamin family - - - 1.006e-223 711.0
HKD3_k127_753283_10 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 395.0
HKD3_k127_753283_11 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 374.0
HKD3_k127_753283_12 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 376.0
HKD3_k127_753283_13 RNA polymerase sigma K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 356.0
HKD3_k127_753283_14 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 316.0
HKD3_k127_753283_15 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 324.0
HKD3_k127_753283_16 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 304.0
HKD3_k127_753283_17 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002219 277.0
HKD3_k127_753283_18 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000001635 241.0
HKD3_k127_753283_19 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000006966 227.0
HKD3_k127_753283_2 Ammonium transporter K03320 - - 7.045e-222 704.0
HKD3_k127_753283_20 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000001195 226.0
HKD3_k127_753283_21 PFAM DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000008227 217.0
HKD3_k127_753283_22 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000001484 222.0
HKD3_k127_753283_23 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000000000000000000000000000000002864 211.0
HKD3_k127_753283_24 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000000003441 205.0
HKD3_k127_753283_25 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000008144 169.0
HKD3_k127_753283_26 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000002321 148.0
HKD3_k127_753283_27 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000000000001434 162.0
HKD3_k127_753283_28 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000002973 121.0
HKD3_k127_753283_29 Membrane fusogenic activity K09806 - - 0.0000000000000000000003454 98.0
HKD3_k127_753283_3 Magnesium chelatase, subunit ChlI K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 614.0
HKD3_k127_753283_30 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000832 83.0
HKD3_k127_753283_31 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000001631 65.0
HKD3_k127_753283_32 Late embryogenesis abundant protein - - - 0.00001795 57.0
HKD3_k127_753283_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 628.0
HKD3_k127_753283_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 550.0
HKD3_k127_753283_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 504.0
HKD3_k127_753283_7 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 425.0
HKD3_k127_753283_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 403.0
HKD3_k127_753283_9 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 400.0
HKD3_k127_757905_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 295.0
HKD3_k127_757905_1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000005162 126.0
HKD3_k127_757905_2 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000008457 69.0
HKD3_k127_7669027_0 Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 507.0
HKD3_k127_7669027_1 Transcriptional regulator - - - 0.000000000000000000000000000000000002408 147.0
HKD3_k127_7669027_2 Cytochrome c554 and c-prime - - - 0.000002458 54.0
HKD3_k127_76720_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 1.552e-211 666.0
HKD3_k127_76720_1 Male sterility protein K02473 - 5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 477.0
HKD3_k127_76720_2 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000001292 201.0
HKD3_k127_7679144_0 Glycolate oxidase subunit GlcD K00104 - 1.1.3.15 3.772e-219 691.0
HKD3_k127_7679144_1 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 608.0
HKD3_k127_7679144_10 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000001158 236.0
HKD3_k127_7679144_11 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000385 229.0
HKD3_k127_7679144_12 YgbB family K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000000000000003027 212.0
HKD3_k127_7679144_13 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000001195 213.0
HKD3_k127_7679144_14 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000000000000000000000000000000000000000178 193.0
HKD3_k127_7679144_15 Tripartite ATP-independent periplasmic transporter, DctQ - - - 0.00000000000000000000000000000000000005148 149.0
HKD3_k127_7679144_16 acetyltransferase - - - 0.000000000000000000000000000000000001687 150.0
HKD3_k127_7679144_2 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 544.0
HKD3_k127_7679144_3 glycolate oxidase iron-sulfur subunit K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 539.0
HKD3_k127_7679144_4 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 487.0
HKD3_k127_7679144_5 Trap dicarboxylate transporter, dctm subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 482.0
HKD3_k127_7679144_6 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 414.0
HKD3_k127_7679144_7 Sugar (and other) transporter K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 316.0
HKD3_k127_7679144_8 Protein of unknown function (DUF533) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 303.0
HKD3_k127_7679144_9 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000002359 248.0
HKD3_k127_7708472_0 Methylmalonyl-CoA mutase K01848 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.4.99.2 3.898e-233 735.0
HKD3_k127_7708472_1 M61 glycyl aminopeptidase - - - 7.988e-215 684.0
HKD3_k127_7708472_10 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 355.0
HKD3_k127_7708472_11 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 300.0
HKD3_k127_7708472_12 Phospholipid-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 302.0
HKD3_k127_7708472_13 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 286.0
HKD3_k127_7708472_14 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001023 293.0
HKD3_k127_7708472_15 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008656 287.0
HKD3_k127_7708472_16 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002678 269.0
HKD3_k127_7708472_17 Ami_2 K03806 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000001393 263.0
HKD3_k127_7708472_18 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000002811 204.0
HKD3_k127_7708472_19 maleylacetoacetate isomerase - - - 0.00000000000000000000000000000000000000000000000000000007327 222.0
HKD3_k127_7708472_2 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 2.767e-202 645.0
HKD3_k127_7708472_20 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.0000000000000000000000000000000000000000000000001226 181.0
HKD3_k127_7708472_21 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000001764 183.0
HKD3_k127_7708472_22 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000123 135.0
HKD3_k127_7708472_23 Phenylacetic acid degradation protein PaaY K02617 - - 0.000000000000000000000000002801 113.0
HKD3_k127_7708472_24 PAS domain - - - 0.000000000000000000001623 99.0
HKD3_k127_7708472_25 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000001035 99.0
HKD3_k127_7708472_26 - K06950 - - 0.000000001414 65.0
HKD3_k127_7708472_27 - - - - 0.00000005045 60.0
HKD3_k127_7708472_3 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 8.706e-196 626.0
HKD3_k127_7708472_4 Sigma-54 interaction domain protein K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 564.0
HKD3_k127_7708472_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 564.0
HKD3_k127_7708472_6 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 549.0
HKD3_k127_7708472_7 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 563.0
HKD3_k127_7708472_8 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 410.0
HKD3_k127_7708472_9 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 359.0
HKD3_k127_7727798_0 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001508 259.0
HKD3_k127_7727798_1 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000132 227.0
HKD3_k127_7727798_2 response regulator K08083 - - 0.00000000001052 66.0
HKD3_k127_7749427_0 Bacterial extracellular solute-binding protein K02027 - - 8.052e-211 662.0
HKD3_k127_7749427_1 Cobalamin-independent synthase, Catalytic domain K00549,K22363 - 2.1.1.14,4.4.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 520.0
HKD3_k127_7749427_10 Cold-shock DNA-binding domain protein K03704 - - 0.000000000000000000000000000000182 124.0
HKD3_k127_7749427_2 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 508.0
HKD3_k127_7749427_3 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 507.0
HKD3_k127_7749427_4 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 473.0
HKD3_k127_7749427_5 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 421.0
HKD3_k127_7749427_6 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 406.0
HKD3_k127_7749427_7 Binding-protein-dependent transport system inner membrane component K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 411.0
HKD3_k127_7749427_8 PFAM binding-protein-dependent transport systems inner membrane component K02046,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 392.0
HKD3_k127_7749427_9 Bacterial extracellular solute-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 362.0
HKD3_k127_7807676_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003687 274.0
HKD3_k127_7807676_1 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000627 261.0
HKD3_k127_7807676_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K07678 - 2.7.13.3,4.6.1.1 0.000000000000000000000000007638 115.0
HKD3_k127_7831418_0 SMART alpha amylase catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 0.0 1487.0
HKD3_k127_7831418_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1050.0
HKD3_k127_7831418_10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 345.0
HKD3_k127_7831418_11 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 377.0
HKD3_k127_7831418_12 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 292.0
HKD3_k127_7831418_13 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001207 269.0
HKD3_k127_7831418_14 squalene-associated FAD-dependent desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006554 271.0
HKD3_k127_7831418_15 PFAM Conserved TM helix repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 254.0
HKD3_k127_7831418_16 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000003144 256.0
HKD3_k127_7831418_17 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000002276 241.0
HKD3_k127_7831418_18 SmpB protein K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000002592 226.0
HKD3_k127_7831418_19 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000008909 226.0
HKD3_k127_7831418_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1007.0
HKD3_k127_7831418_20 dna polymerase iii K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000008285 222.0
HKD3_k127_7831418_21 Type II secretion system protein K K02460 - - 0.000000000000000000000000000000000000000000000000000001415 207.0
HKD3_k127_7831418_22 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000006168 195.0
HKD3_k127_7831418_23 Evidence 4 Homologs of previously reported genes of K09700 - - 0.000000000000000000000000000000000000000000000141 169.0
HKD3_k127_7831418_24 NLP P60 protein - - - 0.0000000000000000000000000000000000000000000001494 175.0
HKD3_k127_7831418_25 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000001075 169.0
HKD3_k127_7831418_26 PFAM Type IV pilus assembly PilZ K02676 - - 0.0000000000000000000000000000000000000000002858 161.0
HKD3_k127_7831418_27 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000001013 161.0
HKD3_k127_7831418_28 Ankyrin repeat K06867 - - 0.00000000000000000000000000000000000001484 154.0
HKD3_k127_7831418_29 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000354 145.0
HKD3_k127_7831418_3 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.304e-292 911.0
HKD3_k127_7831418_30 Type II secretion system (T2SS), protein J K02459 - - 0.000000000000000000001416 106.0
HKD3_k127_7831418_31 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000001118 100.0
HKD3_k127_7831418_32 Belongs to the UPF0125 (RnfH) family K03154,K09801 - - 0.0000000000003096 76.0
HKD3_k127_7831418_33 Bacterial protein of unknown function (DUF883) - - - 0.0000000007614 65.0
HKD3_k127_7831418_34 general secretion pathway protein K02456,K02457,K02458,K02650 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000003393 61.0
HKD3_k127_7831418_35 Universal stress protein family - - - 0.000000571 61.0
HKD3_k127_7831418_36 General secretion pathway K02461 - - 0.000005293 59.0
HKD3_k127_7831418_4 AMP-binding enzyme C-terminal domain K00666 - - 1.511e-216 690.0
HKD3_k127_7831418_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 598.0
HKD3_k127_7831418_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 462.0
HKD3_k127_7831418_7 Alkaline and neutral invertase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008009 439.0
HKD3_k127_7831418_8 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 360.0
HKD3_k127_7831418_9 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 354.0
HKD3_k127_784296_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.23e-211 677.0
HKD3_k127_784296_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 601.0
HKD3_k127_784296_10 Pfam:DUF1049 K08992 - - 0.0000004286 59.0
HKD3_k127_784296_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 451.0
HKD3_k127_784296_3 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 413.0
HKD3_k127_784296_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000002063 270.0
HKD3_k127_784296_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000008045 164.0
HKD3_k127_784296_6 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000003421 173.0
HKD3_k127_784296_7 Nad-dependent epimerase dehydratase K08678 - 4.1.1.35 0.000000000000000000000000000000000000000003435 156.0
HKD3_k127_784296_8 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000001788 143.0
HKD3_k127_784296_9 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000006131 79.0
HKD3_k127_7862085_0 PrkA AAA domain K07180 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 520.0
HKD3_k127_7862085_1 - - - - 0.000000000000000000000000000000000000000000000000000004231 198.0
HKD3_k127_7926150_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 485.0
HKD3_k127_7926150_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 392.0
HKD3_k127_7926150_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 364.0
HKD3_k127_7926150_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000004079 210.0
HKD3_k127_7979694_0 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 525.0
HKD3_k127_7979694_1 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 329.0
HKD3_k127_8126790_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1100.0
HKD3_k127_8126790_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 1.772e-203 640.0
HKD3_k127_8126790_10 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000002015 197.0
HKD3_k127_8126790_11 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000000000000001814 162.0
HKD3_k127_8126790_12 Biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000002563 156.0
HKD3_k127_8126790_13 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000009202 148.0
HKD3_k127_8126790_14 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000000001594 106.0
HKD3_k127_8126790_2 glutaminyl-tRNA K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 471.0
HKD3_k127_8126790_3 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 399.0
HKD3_k127_8126790_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 355.0
HKD3_k127_8126790_5 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 327.0
HKD3_k127_8126790_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 308.0
HKD3_k127_8126790_7 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 301.0
HKD3_k127_8126790_8 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005084 273.0
HKD3_k127_8126790_9 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000001359 249.0
HKD3_k127_8466201_0 ABC transporter transmembrane region K06147,K18893 - - 1.582e-218 694.0
HKD3_k127_8466201_1 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 376.0
HKD3_k127_8466201_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000003091 124.0
HKD3_k127_8466201_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000006403 72.0
HKD3_k127_8466201_4 Histidine kinase-like ATPase domain - - - 0.00000000006849 76.0
HKD3_k127_847681_0 Malic enzyme K00029 - 1.1.1.40 0.0 1069.0
HKD3_k127_847681_1 Cytochrome c-type biogenesis protein CcmF K02198 - - 2.786e-310 962.0
HKD3_k127_847681_10 Catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 477.0
HKD3_k127_847681_11 Amidohydrolase family K05603 - 3.5.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 466.0
HKD3_k127_847681_12 Pfam Binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 409.0
HKD3_k127_847681_13 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 374.0
HKD3_k127_847681_14 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 363.0
HKD3_k127_847681_15 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 350.0
HKD3_k127_847681_16 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 324.0
HKD3_k127_847681_17 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 300.0
HKD3_k127_847681_18 phosphatidate Cytidylyltransferase K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001373 284.0
HKD3_k127_847681_19 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001486 274.0
HKD3_k127_847681_2 PFAM AMP-dependent synthetase and ligase K00666 - - 8.163e-277 880.0
HKD3_k127_847681_20 oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002808 255.0
HKD3_k127_847681_21 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001024 253.0
HKD3_k127_847681_22 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000399 245.0
HKD3_k127_847681_23 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001281 236.0
HKD3_k127_847681_24 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000009275 204.0
HKD3_k127_847681_25 phosphoribosyltransferases - - - 0.000000000000000000000000000000000000000000000000001897 207.0
HKD3_k127_847681_26 ketosteroid isomerase - - - 0.0000000000000000000000000000000000000000000000001012 184.0
HKD3_k127_847681_27 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000009486 185.0
HKD3_k127_847681_28 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000002274 178.0
HKD3_k127_847681_29 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000004731 170.0
HKD3_k127_847681_3 AAA domain - - - 1.726e-257 818.0
HKD3_k127_847681_30 Aspartyl protease - - - 0.0000000000000000000000000000000000000000186 173.0
HKD3_k127_847681_31 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000004385 158.0
HKD3_k127_847681_32 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000001093 150.0
HKD3_k127_847681_33 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000000000000699 145.0
HKD3_k127_847681_34 HutD K09975 - - 0.0000000000000000000000000000000000002622 148.0
HKD3_k127_847681_35 Evidence 2b Function of strongly homologous gene K07497 - - 0.00000000000000000000000000000003222 134.0
HKD3_k127_847681_36 Protein of unknown function (DUF504) - - - 0.000000000000000000000000007332 113.0
HKD3_k127_847681_37 Integrase - - - 0.0000000000000000000000001035 106.0
HKD3_k127_847681_38 Putative prokaryotic signal transducing protein - - - 0.00000000000000005255 93.0
HKD3_k127_847681_39 AMP binding - - - 0.000000000002105 80.0
HKD3_k127_847681_4 Putative methyltransferase - - - 5.943e-239 751.0
HKD3_k127_847681_40 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15555 - - 0.00000002472 66.0
HKD3_k127_847681_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 579.0
HKD3_k127_847681_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 499.0
HKD3_k127_847681_7 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 502.0
HKD3_k127_847681_8 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 469.0
HKD3_k127_847681_9 Dual specificity phosphatase, catalytic domain K01090 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 492.0
HKD3_k127_8502985_0 protein synthesis factor, GTP-binding K06207 - - 6.762e-296 921.0
HKD3_k127_8502985_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.939e-284 893.0
HKD3_k127_8502985_10 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 502.0
HKD3_k127_8502985_11 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 445.0
HKD3_k127_8502985_12 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 433.0
HKD3_k127_8502985_13 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 376.0
HKD3_k127_8502985_14 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 355.0
HKD3_k127_8502985_15 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 349.0
HKD3_k127_8502985_16 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 359.0
HKD3_k127_8502985_17 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 344.0
HKD3_k127_8502985_18 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 347.0
HKD3_k127_8502985_19 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 316.0
HKD3_k127_8502985_2 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 5.213e-272 849.0
HKD3_k127_8502985_20 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000001106 233.0
HKD3_k127_8502985_21 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000008177 235.0
HKD3_k127_8502985_22 Rrf2 family transcriptional regulator, iron-sulfur cluster assembly K13643 - - 0.000000000000000000000000000000000000000000000000000000000000002142 221.0
HKD3_k127_8502985_23 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000000000000003151 222.0
HKD3_k127_8502985_24 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000004591 223.0
HKD3_k127_8502985_25 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000000006247 193.0
HKD3_k127_8502985_26 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000005007 178.0
HKD3_k127_8502985_27 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000000000000000000000000004804 159.0
HKD3_k127_8502985_28 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000007483 144.0
HKD3_k127_8502985_29 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000003328 134.0
HKD3_k127_8502985_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 8.499e-223 694.0
HKD3_k127_8502985_30 Iron-sulphur cluster assembly - - - 0.0000000000000000000000000003569 115.0
HKD3_k127_8502985_31 protein conserved in bacteria K09937 - - 0.0000000000000003635 79.0
HKD3_k127_8502985_32 type 4 pilus biogenesis protein K02656 - - 0.000001888 50.0
HKD3_k127_8502985_4 GcpE protein K03526 - 1.17.7.1,1.17.7.3 1.477e-198 628.0
HKD3_k127_8502985_5 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 606.0
HKD3_k127_8502985_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 594.0
HKD3_k127_8502985_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 545.0
HKD3_k127_8502985_8 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 535.0
HKD3_k127_8502985_9 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 516.0
HKD3_k127_8576355_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1266.0
HKD3_k127_8576355_1 Phosphate acetyl butaryl transferase K00029 - 1.1.1.40 0.0 1132.0
HKD3_k127_8576355_10 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 560.0
HKD3_k127_8576355_11 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 501.0
HKD3_k127_8576355_12 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 496.0
HKD3_k127_8576355_13 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 490.0
HKD3_k127_8576355_14 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 484.0
HKD3_k127_8576355_15 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 455.0
HKD3_k127_8576355_16 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 406.0
HKD3_k127_8576355_17 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 407.0
HKD3_k127_8576355_18 TIGRFAM Succinate dehydrogenase fumarate reductase iron-sulphur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 384.0
HKD3_k127_8576355_19 Mycolic acid cyclopropane synthetase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 394.0
HKD3_k127_8576355_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1049.0
HKD3_k127_8576355_20 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 343.0
HKD3_k127_8576355_21 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 354.0
HKD3_k127_8576355_22 fumarate reductase respiratory complex transmembrane subunit K00246 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 314.0
HKD3_k127_8576355_23 B12 binding domain K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009297 301.0
HKD3_k127_8576355_24 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 290.0
HKD3_k127_8576355_25 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001103 283.0
HKD3_k127_8576355_26 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001617 302.0
HKD3_k127_8576355_27 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001848 269.0
HKD3_k127_8576355_28 Bacterial periplasmic substrate-binding proteins K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000004807 252.0
HKD3_k127_8576355_29 Glutathione peroxidase K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000001562 230.0
HKD3_k127_8576355_3 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - - 7.348e-285 889.0
HKD3_k127_8576355_30 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000006517 209.0
HKD3_k127_8576355_31 Protein of unknown function (DUF3833) - - - 0.000000000000000000000000000000000000000000000000000000001745 223.0
HKD3_k127_8576355_32 outer membrane porin, OprD family - - - 0.000000000000000000000000000000000000000000000000000000002772 216.0
HKD3_k127_8576355_33 - - - - 0.00000000000000000000000000000000000000000000006715 188.0
HKD3_k127_8576355_34 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000000009551 166.0
HKD3_k127_8576355_35 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000002233 164.0
HKD3_k127_8576355_36 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000005729 160.0
HKD3_k127_8576355_37 PGAP1-like protein - - - 0.0000000000000000000000000000000000000006915 161.0
HKD3_k127_8576355_38 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000001727 143.0
HKD3_k127_8576355_39 - - - - 0.0000000000000000000000000000000002192 139.0
HKD3_k127_8576355_4 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 2.436e-282 885.0
HKD3_k127_8576355_40 PFAM poly granule associated family protein - - - 0.000000000000000000000000001974 119.0
HKD3_k127_8576355_41 PFAM acyl-coA-binding protein, ACBP - - - 0.000000000000000000000002086 105.0
HKD3_k127_8576355_42 polyhydroxyalkanoic acid system protein - - - 0.0000000000006865 83.0
HKD3_k127_8576355_43 PFAM CBS domain containing protein - - - 0.00000004638 62.0
HKD3_k127_8576355_5 Fumarate lyase K01744 - 4.3.1.1 1.387e-264 824.0
HKD3_k127_8576355_6 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07791,K07792 - - 1.127e-242 754.0
HKD3_k127_8576355_7 Transporter, DASS family K11106,K14445 - - 6.622e-223 706.0
HKD3_k127_8576355_8 GMC oxidoreductase - - - 3.745e-207 663.0
HKD3_k127_8576355_9 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 565.0
HKD3_k127_8601063_0 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 562.0
HKD3_k127_8623101_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 496.0
HKD3_k127_8623101_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 435.0
HKD3_k127_8623101_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 414.0
HKD3_k127_8623101_3 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 342.0
HKD3_k127_8623101_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 295.0
HKD3_k127_8623101_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000003595 182.0
HKD3_k127_8623101_6 Beta-lactamase enzyme family K07262 - - 0.00000000000000000000000000002314 121.0
HKD3_k127_8623101_7 epimerase K00091 - 1.1.1.219 0.0000000000000000000004258 111.0
HKD3_k127_8623101_8 Copper binding periplasmic protein CusF - - - 0.0000000000000004705 92.0
HKD3_k127_8635771_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 551.0
HKD3_k127_8635771_1 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 498.0
HKD3_k127_8635771_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 330.0
HKD3_k127_8635771_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000002939 198.0
HKD3_k127_8635771_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.00000000000000000000000000000000000000000000006752 171.0
HKD3_k127_8635771_5 AI-2E family transporter - - - 0.0000000000000000000000000003025 123.0
HKD3_k127_8641087_0 Belongs to the HypD family K04654 - - 7.726e-198 631.0
HKD3_k127_8641087_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 484.0
HKD3_k127_8641087_2 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000000000001697 118.0
HKD3_k127_8641087_3 hydrogenase expression formation protein HypE K04655 - - 0.000000000000148 79.0
HKD3_k127_8714073_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.725e-264 822.0
HKD3_k127_8714073_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 3.713e-205 645.0
HKD3_k127_8714073_2 CoA-transferase family III K07749 - 2.8.3.16 9.429e-194 616.0
HKD3_k127_8714073_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 503.0
HKD3_k127_8714073_4 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 483.0
HKD3_k127_8714073_5 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 385.0
HKD3_k127_8714073_6 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 291.0
HKD3_k127_8714073_7 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.000000000000000000000000000000000000000000000000000000007667 204.0
HKD3_k127_8714073_8 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000005544 207.0
HKD3_k127_8714073_9 CBS domain K04767 - - 0.000000000000000004306 94.0
HKD3_k127_8715606_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 8.58e-230 738.0
HKD3_k127_8715606_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 448.0
HKD3_k127_8715606_2 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000000000005785 161.0
HKD3_k127_8715606_3 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000002718 131.0
HKD3_k127_8752823_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 495.0
HKD3_k127_8752823_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007484 291.0
HKD3_k127_8752823_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003005 252.0
HKD3_k127_8760026_0 PFAM PfkB domain protein K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 342.0
HKD3_k127_8760026_1 KR domain K00034,K00046,K00059,K00216 - 1.1.1.100,1.1.1.47,1.1.1.69,1.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001528 287.0
HKD3_k127_8760026_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001624 258.0
HKD3_k127_8760026_3 Aldolase K01631 - 4.1.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000005797 246.0
HKD3_k127_8760026_4 PFAM 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.00000000000000000000000000000000000000000000000000000000000000000002003 244.0
HKD3_k127_8760026_5 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000004637 233.0
HKD3_k127_8760026_6 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000001294 218.0
HKD3_k127_8760026_7 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000004272 152.0
HKD3_k127_8760026_8 Uncharacterized ACR, COG1993 - - - 0.000000000000000000000000000000275 132.0
HKD3_k127_8760026_9 SnoaL-like domain - - - 0.000000000000000000000005605 104.0
HKD3_k127_8771882_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 2.101e-312 967.0
HKD3_k127_8771882_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 2.794e-267 832.0
HKD3_k127_8771882_10 Molybdenum ABC transporter periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 295.0
HKD3_k127_8771882_11 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 294.0
HKD3_k127_8771882_12 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006911 284.0
HKD3_k127_8771882_13 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008483 268.0
HKD3_k127_8771882_14 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001499 252.0
HKD3_k127_8771882_15 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000000000000000000000000000000000000000000009449 199.0
HKD3_k127_8771882_16 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000001208 206.0
HKD3_k127_8771882_17 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000004773 203.0
HKD3_k127_8771882_18 regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000003191 186.0
HKD3_k127_8771882_19 Protein of unknown function (DUF3106) - - - 0.000000000000000000000000003458 124.0
HKD3_k127_8771882_2 TIGRFAM malate synthase A K01638 - 2.3.3.9 3.779e-257 804.0
HKD3_k127_8771882_20 PFAM RDD domain containing protein - - - 0.0000000000000000004125 94.0
HKD3_k127_8771882_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 7.235e-235 743.0
HKD3_k127_8771882_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 582.0
HKD3_k127_8771882_5 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 474.0
HKD3_k127_8771882_6 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007968 394.0
HKD3_k127_8771882_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 329.0
HKD3_k127_8771882_8 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 298.0
HKD3_k127_8771882_9 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 291.0
HKD3_k127_8924238_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 459.0
HKD3_k127_8924238_1 Pterin binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 303.0
HKD3_k127_8924238_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000299 287.0
HKD3_k127_8943645_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 5.161e-236 740.0
HKD3_k127_8943645_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 493.0
HKD3_k127_8943645_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000005773 164.0
HKD3_k127_896965_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 323.0
HKD3_k127_896965_1 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000008801 199.0
HKD3_k127_896965_2 - - - - 0.0000000000000000000000000000000000002523 159.0
HKD3_k127_896965_3 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.000000000000000000000000001619 118.0
HKD3_k127_8984741_0 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006548 259.0
HKD3_k127_9019573_0 ABC transporter K06020 - 3.6.3.25 9.406e-293 905.0
HKD3_k127_9019573_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.568e-230 729.0
HKD3_k127_9019573_10 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 293.0
HKD3_k127_9019573_11 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000002197 232.0
HKD3_k127_9019573_12 mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000005622 251.0
HKD3_k127_9019573_13 Phosphotransferase system, mannose fructose-specific component IIA K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000002093 168.0
HKD3_k127_9019573_14 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000002701 135.0
HKD3_k127_9019573_15 Transcriptional regulator, LysR family K21703 - - 0.0000000000000000001908 89.0
HKD3_k127_9019573_16 Domain of unknown function (DUF4124) - - - 0.0000000000000000007618 96.0
HKD3_k127_9019573_17 PTS HPr component phosphorylation site - - - 0.0000000000000001071 85.0
HKD3_k127_9019573_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.973e-220 693.0
HKD3_k127_9019573_3 ABC transporter K06158 - - 6.655e-215 686.0
HKD3_k127_9019573_4 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 4.575e-212 675.0
HKD3_k127_9019573_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.302e-211 666.0
HKD3_k127_9019573_6 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 3.02e-199 635.0
HKD3_k127_9019573_7 AmpG muropeptide MFS transporter K08218 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 595.0
HKD3_k127_9019573_8 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 402.0
HKD3_k127_9019573_9 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 352.0
HKD3_k127_9203859_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 8.586e-216 690.0
HKD3_k127_9203859_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.498e-215 685.0
HKD3_k127_9340280_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 5.44e-315 972.0
HKD3_k127_9340280_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 6.203e-234 741.0
HKD3_k127_9340280_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 542.0
HKD3_k127_9340280_3 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 426.0
HKD3_k127_9340280_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 367.0
HKD3_k127_9340280_5 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 286.0
HKD3_k127_9340280_6 Succinate dehydrogenase, hydrophobic K00242 - - 0.0000000000000000000000000000000008685 137.0
HKD3_k127_9340280_7 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.0000000000000000000000000001557 126.0
HKD3_k127_9340280_8 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000007521 79.0
HKD3_k127_9340280_9 Protein of unknown function (DUF3617) - - - 0.000000000000711 72.0
HKD3_k127_9431732_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1514.0
HKD3_k127_9431732_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.341e-223 718.0
HKD3_k127_9431732_10 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002205 291.0
HKD3_k127_9431732_11 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006285 267.0
HKD3_k127_9431732_12 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000005183 195.0
HKD3_k127_9431732_13 Shikimate kinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000378 179.0
HKD3_k127_9431732_14 MarC family integral membrane protein - - - 0.00000000000000000000000001984 111.0
HKD3_k127_9431732_15 AAA domain - - - 0.000000001913 71.0
HKD3_k127_9431732_2 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 1.883e-215 686.0
HKD3_k127_9431732_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 567.0
HKD3_k127_9431732_4 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 468.0
HKD3_k127_9431732_5 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 445.0
HKD3_k127_9431732_6 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 412.0
HKD3_k127_9431732_7 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 391.0
HKD3_k127_9431732_8 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 315.0
HKD3_k127_9431732_9 MASE2 domain K18968 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005575 293.0
HKD3_k127_966518_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 484.0
HKD3_k127_966518_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 416.0
HKD3_k127_966518_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000001527 117.0
HKD3_k127_966518_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000006944 106.0
HKD3_k127_966518_12 - - - - 0.000000000000002134 87.0
HKD3_k127_966518_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 401.0
HKD3_k127_966518_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 369.0
HKD3_k127_966518_4 Sec-independent protein translocase protein (TatC) K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 318.0
HKD3_k127_966518_5 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 321.0
HKD3_k127_966518_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 291.0
HKD3_k127_966518_7 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000000008008 198.0
HKD3_k127_966518_8 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000000000003162 175.0
HKD3_k127_966518_9 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000000000000005807 136.0